MCL coexpression mm9:1324

Phase1 CAGE Peaks

	Short description
Mm9::chr12:36719487..36719504,+	p1@Agr2
Mm9::chr3:116414693..116414702,-	p13@Slc35a3
Mm9::chr3:116414738..116414765,-	p6@Slc35a3
Mm9::chr3:116414767..116414783,-	p8@Slc35a3
Mm9::chr3:116414784..116414800,-	p5@Slc35a3
Mm9::chr7:133904212..133904258,+	p4@Mapk3

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0015780	nucleotide-sugar transport	0.0228469674105612
GO:0005338	nucleotide-sugar transmembrane transporter activity	0.0228469674105612
GO:0001784	phosphotyrosine binding	0.0228469674105612
GO:0045309	protein phosphorylated amino acid binding	0.0228469674105612
GO:0043330	response to exogenous dsRNA	0.0228469674105612
GO:0031663	lipopolysaccharide-mediated signaling pathway	0.0228469674105612
GO:0032496	response to lipopolysaccharide	0.0228469674105612
GO:0051219	phosphoprotein binding	0.0228469674105612
GO:0004707	MAP kinase activity	0.0228469674105612
GO:0043331	response to dsRNA	0.0228469674105612
GO:0002237	response to molecule of bacterial origin	0.0271547771255137
GO:0019233	sensory perception of pain	0.0365896572455163
GO:0005351	sugar:hydrogen ion symporter activity	0.045628859221562
GO:0051119	sugar transmembrane transporter activity	0.045628859221562
GO:0015144	carbohydrate transmembrane transporter activity	0.045628859221562
GO:0004702	receptor signaling protein serine/threonine kinase activity	0.0495272551654839
GO:0051216	cartilage development	0.0495272551654839

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
gastrointestinal system	8.23e-22	47
intestine	2.82e-17	31
mucosa	1.70e-09	15
intestinal mucosa	5.83e-08	13
anatomical wall	5.83e-08	13
wall of intestine	5.83e-08	13
gastrointestinal system mucosa	5.83e-08	13
digestive system	2.55e-07	116
digestive tract	2.55e-07	116
primitive gut	2.55e-07	116
endoderm-derived structure	7.06e-07	118
endoderm	7.06e-07	118
presumptive endoderm	7.06e-07	118

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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