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Coexpression cluster:C518

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Full id: C518_sacrococcigeal_Prostate_Mesenchymal_Fibroblast_tridermal_Hair_placenta



Phase1 CAGE Peaks

Hg19::chr22:45898754..45898771,+p1@FBLN1
Hg19::chr22:45928975..45928998,+p5@FBLN1
Hg19::chr22:45929702..45929734,+p3@FBLN1
Hg19::chr22:45938067..45938094,+p@chr22:45938067..45938094
+
Hg19::chr22:45938119..45938132,+p@chr22:45938119..45938132
+
Hg19::chr22:45939285..45939335,+p@chr22:45939285..45939335
+
Hg19::chr22:45939339..45939352,+p@chr22:45939339..45939352
+
Hg19::chr22:45939357..45939377,+p@chr22:45939357..45939377
+
Hg19::chr22:45942994..45943026,+p@chr22:45942994..45943026
+
Hg19::chr22:45943028..45943051,+p@chr22:45943028..45943051
+
Hg19::chr22:45944499..45944509,+p@chr22:45944499..45944509
+
Hg19::chr22:45944516..45944530,+p@chr22:45944516..45944530
+
Hg19::chr22:45946433..45946447,+p@chr22:45946433..45946447
+
Hg19::chr22:45958815..45958838,+p@chr22:45958815..45958838
+
Hg19::chr22:45958840..45958880,+p@chr22:45958840..45958880
+
Hg19::chr22:45958878..45958908,-p@chr22:45958878..45958908
-
Hg19::chr22:45958896..45958922,+p@chr22:45958896..45958922
+
Hg19::chr22:45996721..45996735,+p2@FBLN1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
non-terminally differentiated cell7.03e-22180
fibroblast2.96e-1475
Uber Anatomy
Ontology termp-valuen
multi-tissue structure7.42e-24347
organism subdivision2.61e-20365
multi-cellular organism1.09e-19659
surface structure2.75e-1595
mesenchyme1.83e-13238
entire embryonic mesenchyme1.83e-13238
anatomical system6.08e-13625
anatomical group1.19e-12626
embryo1.57e-12612
organ part2.20e-12219
organ5.06e-12511
trunk mesenchyme3.44e-11143
endoderm-derived structure6.69e-11169
endoderm6.69e-11169
presumptive endoderm6.69e-11169
embryonic structure8.15e-11605
developing anatomical structure8.15e-11605
germ layer1.65e-10604
embryonic tissue1.65e-10604
presumptive structure1.65e-10604
epiblast (generic)1.65e-10604
trunk2.47e-10216
cell layer4.13e-10312
digestive system6.31e-10155
digestive tract6.31e-10155
primitive gut6.31e-10155
somite6.91e-1083
paraxial mesoderm6.91e-1083
presomitic mesoderm6.91e-1083
presumptive segmental plate6.91e-1083
trunk paraxial mesoderm6.91e-1083
presumptive paraxial mesoderm6.91e-1083
epithelium1.68e-09309
organ component layer6.86e-0957
multilaminar epithelium1.95e-0882
ectoderm4.65e-08173
presumptive ectoderm4.65e-08173
dermomyotome5.14e-0870
ectoderm-derived structure5.80e-08169
anatomical cluster7.83e-08286
subdivision of head1.08e-0748
integument2.35e-0745
integumental system2.35e-0745
mixed endoderm/mesoderm-derived structure8.09e-07130
organ segment9.62e-0797


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.