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MCL coexpression mm9:1004

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Phase1 CAGE Peaks

 Short description
Mm9::chr9:98855201..98855222,-p@chr9:98855201..98855222
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Mm9::chr9:98855692..98855710,+p2@Foxl2
Mm9::chr9:98855721..98855732,-p2@Foxl2os
Mm9::chr9:98855759..98855767,-p3@Foxl2os
Mm9::chr9:98855847..98855866,+p3@Foxl2
Mm9::chr9:98855868..98855895,+p1@Foxl2
Mm9::chr9:98855944..98855971,+p4@Foxl2
Mm9::chr9:98857712..98857715,-p@chr9:98857712..98857715
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0019101female somatic sex determination0.00169835095600723
GO:0030237female sex determination0.00169835095600723
GO:0060014granulosa cell differentiation0.00169835095600723
GO:0018993somatic sex determination0.00254752643401085
GO:0048048embryonic eye morphogenesis0.00611406344162603
GO:0001541ovarian follicle development0.0134654968654859
GO:0048562embryonic organ morphogenesis0.0134654968654859
GO:0007530sex determination0.0134654968654859
GO:0022601menstrual cycle phase0.0134654968654859
GO:0022602menstrual cycle process0.0134654968654859
GO:0008585female gonad development0.0134654968654859
GO:0046545development of primary female sexual characteristics0.0134654968654859
GO:0046660female sex differentiation0.0134654968654859
GO:0048568embryonic organ development0.0134654968654859
GO:0042698menstrual cycle0.0135868076480578
GO:0048592eye morphogenesis0.0136929545828083
GO:0008406gonad development0.0150021001113972
GO:0048608reproductive structure development0.0150021001113972
GO:0045137development of primary sexual characteristics0.0155533192813294
GO:0048609reproductive process in a multicellular organism0.0169063117893447
GO:0032504multicellular organism reproduction0.0169063117893447
GO:0007548sex differentiation0.0169063117893447
GO:0003006reproductive developmental process0.0190510672456463
GO:0001654eye development0.022078562428094
GO:0006917induction of apoptosis0.0252793007682615
GO:0012502induction of programmed cell death0.0252793007682615
GO:0043065positive regulation of apoptosis0.0300244186865564
GO:0043068positive regulation of programmed cell death0.0300244186865564
GO:0007423sensory organ development0.0326786149466219
GO:0045944positive regulation of transcription from RNA polymerase II promoter0.0327994028378897
GO:0048598embryonic morphogenesis0.0327994028378897
GO:0022414reproductive process0.0327994028378897
GO:0045893positive regulation of transcription, DNA-dependent0.0364373477834279
GO:0045941positive regulation of transcription0.0417794335177779
GO:0045935positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0417794335177779
GO:0031325positive regulation of cellular metabolic process0.0484030022462061
GO:0009893positive regulation of metabolic process0.0484030022462061
GO:0042981regulation of apoptosis0.0484030022462061
GO:0043067regulation of programmed cell death0.0484030022462061
GO:0006357regulation of transcription from RNA polymerase II promoter0.0484030022462061



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
pituitary gland6.12e-138
gland of diencephalon6.12e-138
neuroendocrine gland6.12e-138
pre-chordal neural plate7.27e-1349
diencephalon2.33e-1210
future diencephalon2.33e-1210
female reproductive system1.54e-119
neurectoderm6.35e-1164
neural plate6.35e-1164
presumptive neural plate6.35e-1164
female reproductive organ5.06e-108
female organism4.40e-0911
reproductive structure8.80e-0926
reproductive system8.80e-0926
ecto-epithelium1.16e-0873
eye2.00e-089
camera-type eye2.00e-089
simple eye2.00e-089
immature eye2.00e-089
ocular region2.00e-089
visual system2.00e-089
face2.00e-089
optic cup2.00e-089
optic vesicle2.00e-089
eye primordium2.00e-089
reproductive organ3.45e-0824
regional part of forebrain1.33e-0739
forebrain1.33e-0739
future forebrain1.33e-0739
regional part of brain1.81e-0746
anterior neural tube2.66e-0740
brain3.31e-0747
future brain3.31e-0747
neural tube8.85e-0752
neural rod8.85e-0752
future spinal cord8.85e-0752
neural keel8.85e-0752


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.45843
MA0004.10.434673
MA0006.10.271714
MA0007.10.419994
MA0009.10.870101
MA0014.14.06656
MA0017.10.804572
MA0019.10.688051
MA0024.10.826339
MA0025.11.10341
MA0027.12.51754
MA0028.10.281528
MA0029.10.804619
MA0030.10.811181
MA0031.10.775627
MA0038.10.577528
MA0040.10.882616
MA0041.10.360875
MA0042.10.348174
MA0043.10.966833
MA0046.10.906029
MA0048.10.102483
MA0050.10.472794
MA0051.10.586414
MA0052.10.890676
MA0055.10.0283571
MA0056.10
MA0057.11.58436
MA0058.10.341628
MA0059.10.353484
MA0060.10.197678
MA0061.10.224905
MA0063.10
MA0066.10.566617
MA0067.11.21448
MA0068.10.319589
MA0069.10.891016
MA0070.10.881319
MA0071.10.471969
MA0072.10.872842
MA0073.10.082812
MA0074.10.531046
MA0076.10.315013
MA0077.10.851175
MA0078.10.61926
MA0081.10.980744
MA0083.10.96604
MA0084.11.54225
MA0087.10.922929
MA0088.10.064239
MA0089.10
MA0090.11.82869
MA0091.10.447561
MA0092.10.401504
MA0093.10.289361
MA0095.10
MA0098.10
MA0100.10.519598
MA0101.10.362124
MA0103.10.307078
MA0105.10.133231
MA0106.10.626997
MA0107.10.301222
MA0108.20.710846
MA0109.10
MA0111.10.415012
MA0113.10.598933
MA0114.11.18683
MA0115.10.969632
MA0116.10.27152
MA0117.10.937363
MA0119.10.362692
MA0122.10.957212
MA0124.11.16127
MA0125.11.0872
MA0130.10
MA0131.10.683521
MA0132.10
MA0133.10
MA0135.11.00325
MA0136.10.550755
MA0139.11.55504
MA0140.10.519484
MA0141.10.325895
MA0142.10.761136
MA0143.10.615203
MA0144.10.225588
MA0145.10.900473
MA0146.13.23209
MA0147.10.236889
MA0148.10.450593
MA0149.10.367458
MA0062.20.137653
MA0035.20.524137
MA0039.22.43328
MA0138.20.675599
MA0002.20.172399
MA0137.20.32312
MA0104.20.18504
MA0047.20.576767
MA0112.20.2464
MA0065.20.902537
MA0150.10.419883
MA0151.10
MA0152.10.576873
MA0153.11.01988
MA0154.12.91306
MA0155.10.978338
MA0156.10.314185
MA0157.10.729116
MA0158.10
MA0159.10.688775
MA0160.10.453546
MA0161.10
MA0162.11.4435
MA0163.10.669601
MA0164.10.551114
MA0080.20.302064
MA0018.20.560731
MA0099.20.669311
MA0079.210.1641
MA0102.21.59466
MA0258.10.210437
MA0259.10.227035
MA0442.10
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