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Coexpression cluster:C828

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Full id: C828_diaphragm_tongue_throat_Fibroblast_pituitary_cerebellum_testicular



Phase1 CAGE Peaks

Hg19::chr14:101292448..101292462,+p1@MEG3
Hg19::chr14:101295039..101295051,+p32@MEG3
Hg19::chr14:101295407..101295466,-p@chr14:101295407..101295466
-
Hg19::chr14:101295520..101295544,+p10@MEG3
Hg19::chr14:101295725..101295752,+p19@MEG3
Hg19::chr14:101295859..101295881,+p17@MEG3
Hg19::chr14:101296006..101296031,+p37@MEG3
Hg19::chr14:101297740..101297760,+p40@MEG3
Hg19::chr14:101416170..101416174,+p1@SNORD114-1
Hg19::chr14:101442373..101442374,+p1@SNORD114-19


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube1.10e-3456
neural rod1.10e-3456
future spinal cord1.10e-3456
neural keel1.10e-3456
regional part of nervous system6.46e-3353
regional part of brain6.46e-3353
brain4.51e-2968
future brain4.51e-2968
central nervous system4.34e-2881
nervous system2.80e-2789
neurectoderm6.68e-2786
regional part of forebrain1.27e-2641
forebrain1.27e-2641
anterior neural tube1.27e-2641
future forebrain1.27e-2641
neural plate2.18e-2582
presumptive neural plate2.18e-2582
brain grey matter3.31e-2434
gray matter3.31e-2434
telencephalon3.32e-2334
cerebral hemisphere7.08e-2332
regional part of telencephalon9.56e-2332
ectoderm-derived structure7.21e-21171
ectoderm7.21e-21171
presumptive ectoderm7.21e-21171
structure with developmental contribution from neural crest1.21e-18132
cerebral cortex2.79e-1825
pallium2.79e-1825
regional part of cerebral cortex1.20e-1722
pre-chordal neural plate4.16e-1761
ecto-epithelium5.70e-17104
neocortex5.14e-1620
adult organism6.09e-16114
organ system subdivision3.42e-11223
multi-cellular organism3.28e-09656
posterior neural tube3.93e-0915
chordal neural plate3.93e-0915
organ part6.55e-08218
basal ganglion1.15e-079
nuclear complex of neuraxis1.15e-079
aggregate regional part of brain1.15e-079
collection of basal ganglia1.15e-079
cerebral subcortex1.15e-079
segmental subdivision of hindbrain1.70e-0712
hindbrain1.70e-0712
presumptive hindbrain1.70e-0712
neural nucleus2.31e-079
nucleus of brain2.31e-079
anatomical conduit4.27e-07240
multi-tissue structure6.72e-07342
organ8.57e-07503
anatomical system8.61e-07624
temporal lobe8.90e-076


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.