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Coexpression cluster:C1799

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Full id: C1799_occipital_duodenum_temporal_Wilms_brain_pineal_parietal



Phase1 CAGE Peaks

Hg19::chr18:43913919..43913967,+p2@RNF165
Hg19::chr18:43913973..43914005,+p1@RNF165
Hg19::chr18:43914019..43914036,+p4@RNF165
Hg19::chr18:43914051..43914066,+p5@RNF165
Hg19::chr18:43914159..43914222,+p3@RNF165


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
central nervous system3.09e-3182
regional part of nervous system2.63e-3094
nervous system2.63e-3094
neural tube5.34e-2757
neural rod5.34e-2757
future spinal cord5.34e-2757
neural keel5.34e-2757
brain2.06e-2669
future brain2.06e-2669
adult organism7.69e-26115
regional part of brain7.45e-2559
neurectoderm4.38e-2390
neural plate1.32e-2286
presumptive neural plate1.32e-2286
anterior neural tube1.58e-2242
regional part of forebrain1.69e-2241
forebrain1.69e-2241
future forebrain1.69e-2241
ectoderm4.63e-21173
presumptive ectoderm4.63e-21173
ectoderm-derived structure1.91e-20169
telencephalon4.36e-1934
cerebral hemisphere7.39e-1932
gray matter8.84e-1934
brain grey matter8.84e-1934
regional part of telencephalon1.90e-1833
pre-chordal neural plate2.84e-1761
anterior region of body5.25e-16129
craniocervical region5.25e-16129
regional part of cerebral cortex1.89e-1522
cerebral cortex2.06e-1525
pallium2.06e-1525
head2.78e-15123
neocortex2.69e-1420
organ part6.97e-11219
embryo2.97e-08612
respiratory tract6.21e-0853
embryonic structure9.11e-07605
developing anatomical structure9.11e-07605


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.