UBERON:0000074

Name:	renal glomerulus
Definition:	"A capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney[GO]." [MP:0005325, Wikipedia:Glomerulus]
Xrefs:	Expandlinks: AAO:0010388 BTO:0000530 EFO:0003667 EV:0100386 FMA:15624 [1] [ 200px-Gray1130.svg.png] MA:0001657 MESH:A.05.810.453.736.520 ncithesaurus:Glomerulus XAO:0000146 ZFA:0001288
Synonyms:	"glomerular capillary tuft" RELATED [ZFA:0001288] "glomerular tuft" RELATED [] "glomerulus" BROAD [] "malphigian glomerulus" RELATED [BTO:0000530] "renal corpuscle" RELATED []
Comments:	ZFA - The multi-tissue structure where the glomerular basement membrane supported by mesonephric podocytes filters blood from the glomerular capillaries. TODO - split glomerulus and glomerular tuft? DONE. GUDMAP: 'Together, the Bowman窶冱 capsule and the glomerulus comprise the definitive renal corpuscle.' - here the glomerulus is part of the capsule?
Subset:	vertebrate_core
Created by:	Melissa Haendel
Creation date:	2009-06-18T09:26:37Z

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

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Parents

is_a:	UBERON:0000064(organ part),UBERON:0004120(mesoderm-derived structure)
develops_from:	UBERON:0003220(metanephric mesenchyme),UBERON:0005749(glomerular tuft)
part_of:	UBERON:0001229(renal corpuscle)

Children

part of:	CL:0002188 (glomerular endothelial cell),UBERON:0002319 (mesangium),CL:1000746 (glomerular cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

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Human (Homo sapiens)

• 11514-119H2 (Renal Glomerular Endothelial Cells, donor1)
• 11518-119H6 (Renal Mesangial Cells, donor1)
• 11590-120G6 (Alveolar Epithelial Cells, donor2)
• 11594-120H1 (Renal Glomerular Endothelial Cells, donor2)
• 11598-120H5 (Renal Mesangial Cells, donor2)
• 11675-122H1 (Renal Glomerular Endothelial Cells, donor3)
• 11679-122H5 (Renal Mesangial Cells, donor3)
• 11783-124B1 (Renal Glomerular Endothelial Cells, donor4)

Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000074 (renal glomerulus), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

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P-value	FFCP	Short description

P-value	FFCP	Short description
6.87e-64	FFCP PHASE2:Hg19::chr2:120409486..120409492,+	p@chr2:120409486..120409492, +
6.87e-64	FFCP PHASE1:Hg19::chr2:120409486..120409492,+	p@chr2:120409486..120409492, +
9.62e-40	FFCP PHASE1:Hg19::chr1:94713418..94713436,+	p1@ENST00000413103
9.62e-40	FFCP PHASE2:Hg19::chr1:94713418..94713436,+	p1@ENST00000413103
1.16e-36	FFCP PHASE2:Hg19::chr17:79426453..79426462,+	p@chr17:79426453..79426462, +
1.16e-36	FFCP PHASE1:Hg19::chr17:79426453..79426462,+	p@chr17:79426453..79426462, +
1.31e-36	FFCP PHASE1:Hg19::chr8:77557753..77557755,-	p@chr8:77557753..77557755, -
1.31e-36	FFCP PHASE2:Hg19::chr8:77557753..77557755,-	p@chr8:77557753..77557755, -
5.58e-32	FFCP PHASE2:Hg19::chr1:32042764..32042776,+	p6@TINAGL1
5.58e-32	FFCP PHASE1:Hg19::chr1:32042764..32042776,+	p6@TINAGL1
1.53e-30	FFCP PHASE1:Hg19::chr15:91416076..91416089,+	p9@FURIN
1.53e-30	FFCP PHASE2:Hg19::chr15:91416076..91416089,+	p9@FURIN
3.83e-30	FFCP PHASE2:Hg19::chr20:6034598..6034603,-	p7@LRRN4
3.83e-30	FFCP PHASE1:Hg19::chr20:6034598..6034603,-	p7@LRRN4
1.78e-29	FFCP PHASE1:Hg19::chr22:47030082..47030087,+	p@chr22:47030082..47030087, +
1.78e-29	FFCP PHASE2:Hg19::chr1:42777312..42777314,+	p@chr1:42777312..42777314, +
1.78e-29	FFCP PHASE2:Hg19::chr2:26700984..26700993,-	p7@OTOF
1.78e-29	FFCP PHASE2:Hg19::chr6:18225523..18225534,-	p@chr6:18225523..18225534, -
1.78e-29	FFCP PHASE2:Hg19::chr2:26700331..26700340,-	p@chr2:26700331..26700340, -
1.78e-29	FFCP PHASE1:Hg19::chr1:42777312..42777314,+	p@chr1:42777312..42777314, +
1.78e-29	FFCP PHASE1:Hg19::chr2:26700984..26700993,-	p7@OTOF
1.78e-29	FFCP PHASE1:Hg19::chr6:18225523..18225534,-	p@chr6:18225523..18225534, -
1.78e-29	FFCP PHASE2:Hg19::chr22:47030082..47030087,+	p@chr22:47030082..47030087, +
1.78e-29	FFCP PHASE1:Hg19::chr2:26700331..26700340,-	p@chr2:26700331..26700340, -
7.96e-27	FFCP PHASE2:Hg19::chr10:3477893..3477912,-	p@chr10:3477893..3477912, -
7.96e-27	FFCP PHASE1:Hg19::chr10:3477893..3477912,-	p@chr10:3477893..3477912, -
6.29e-26	FFCP PHASE1:Hg19::chr1:172926077..172926120,-	p@chr1:172926077..172926120, -
6.29e-26	FFCP PHASE2:Hg19::chr1:172926077..172926120,-	p@chr1:172926077..172926120, -
6.32e-26	FFCP PHASE1:Hg19::chrX:128782722..128782738,-	p5@APLN
6.32e-26	FFCP PHASE2:Hg19::chrX:128782722..128782738,-	p5@APLN
9.89e-26	FFCP PHASE1:Hg19::chr2:693380..693398,+	p@chr2:693380..693398, +
9.89e-26	FFCP PHASE2:Hg19::chr2:693380..693398,+	p@chr2:693380..693398, +
1.28e-23	FFCP PHASE2:Hg19::chr6:84849252..84849259,+	p@chr6:84849252..84849259, +
1.28e-23	FFCP PHASE2:Hg19::chr2:133426030..133426041,-	p@chr2:133426030..133426041, -
1.28e-23	FFCP PHASE1:Hg19::chr6:84849252..84849259,+	p@chr6:84849252..84849259, +
1.28e-23	FFCP PHASE1:Hg19::chr2:133426030..133426041,-	p@chr2:133426030..133426041, -
1.44e-23	FFCP PHASE2:Hg19::chr1:51791596..51791607,-	p23@TTC39A
1.44e-23	FFCP PHASE2:Hg19::chr7:28998254..28998261,-	p10@TRIL
1.44e-23	FFCP PHASE1:Hg19::chr1:51791596..51791607,-	p23@TTC39A
1.44e-23	FFCP PHASE1:Hg19::chr7:28998254..28998261,-	p10@TRIL
1.61e-23	FFCP PHASE1:Hg19::chr7:4051097..4051112,+	p@chr7:4051097..4051112, +
1.61e-23	FFCP PHASE1:Hg19::chr15:85403302..85403304,+	p@chr15:85403302..85403304, +
1.61e-23	FFCP PHASE2:Hg19::chr7:4051097..4051112,+	p@chr7:4051097..4051112, +
1.61e-23	FFCP PHASE2:Hg19::chr15:85403302..85403304,+	p@chr15:85403302..85403304, +
1.8e-23	FFCP PHASE1:Hg19::chr16:2141529..2141537,+	p@chr16:2141529..2141537, +
1.8e-23	FFCP PHASE2:Hg19::chr16:2141529..2141537,+	p@chr16:2141529..2141537, +
2.92e-22	FFCP PHASE2:Hg19::chr5:74244100..74244117,+	p@chr5:74244100..74244117, +
2.92e-22	FFCP PHASE1:Hg19::chr5:74244100..74244117,+	p@chr5:74244100..74244117, +
5.69e-22	FFCP PHASE2:Hg19::chr5:148651758..148651769,-	p@chr5:148651758..148651769, -
5.69e-22	FFCP PHASE1:Hg19::chr5:148651758..148651769,-	p@chr5:148651758..148651769, -
2.9e-21	FFCP PHASE2:Hg19::chr16:86768403..86768437,+	p@chr16:86768403..86768437, +
2.9e-21	FFCP PHASE1:Hg19::chr16:86768403..86768437,+	p@chr16:86768403..86768437, +
4.78e-21	FFCP PHASE2:Hg19::chr17:2076002..2076026,-	p@chr17:2076002..2076026, -
4.78e-21	FFCP PHASE1:Hg19::chr17:2076002..2076026,-	p@chr17:2076002..2076026, -
1.26e-20	FFCP PHASE1:Hg19::chr1:32712897..32712909,+	p3@FAM167B
1.26e-20	FFCP PHASE2:Hg19::chr1:32712897..32712909,+	p3@FAM167B
2.32e-20	FFCP PHASE1:Hg19::chr11:124628392..124628427,-	p@chr11:124628392..124628427, -
2.32e-20	FFCP PHASE2:Hg19::chr11:124628392..124628427,-	p@chr11:124628392..124628427, -
3.42e-20	FFCP PHASE1:Hg19::chr3:98591021..98591026,-	p1@ENST00000487339
3.42e-20	FFCP PHASE2:Hg19::chr3:98591021..98591026,-	p1@ENST00000487339
3.44e-20	FFCP PHASE2:Hg19::chr19:47231340..47231383,-	p@chr19:47231340..47231383, -
3.44e-20	FFCP PHASE1:Hg19::chr19:47231340..47231383,-	p@chr19:47231340..47231383, -
3.58e-20	FFCP PHASE1:Hg19::chr19:1826957..1826984,-	p@chr19:1826957..1826984, -
3.58e-20	FFCP PHASE2:Hg19::chr19:1826957..1826984,-	p@chr19:1826957..1826984, -
4.39e-20	FFCP PHASE1:Hg19::chr4:38057595..38057624,-	p@chr4:38057595..38057624, -
4.39e-20	FFCP PHASE2:Hg19::chr4:38057595..38057624,-	p@chr4:38057595..38057624, -
7.13e-20	FFCP PHASE1:Hg19::chr2:133426106..133426117,-	p@chr2:133426106..133426117, -
7.13e-20	FFCP PHASE2:Hg19::chr2:133426106..133426117,-	p@chr2:133426106..133426117, -
7.84e-20	FFCP PHASE2:Hg19::chr9:35753821..35753835,-	p@chr9:35753821..35753835, -
7.84e-20	FFCP PHASE1:Hg19::chr15:36653709..36653720,-	p@chr15:36653709..36653720, -
7.84e-20	FFCP PHASE2:Hg19::chr15:36653709..36653720,-	p@chr15:36653709..36653720, -
7.84e-20	FFCP PHASE1:Hg19::chr9:35753821..35753835,-	p@chr9:35753821..35753835, -
8.62e-20	FFCP PHASE2:Hg19::chr4:145568170..145568180,-	p@chr4:145568170..145568180, -
8.62e-20	FFCP PHASE1:Hg19::chr4:145568170..145568180,-	p@chr4:145568170..145568180, -
1.04e-19	FFCP PHASE1:Hg19::chr19:38397228..38397266,-	p1@WDR87
1.04e-19	FFCP PHASE2:Hg19::chr19:38397228..38397266,-	p1@WDR87
1.15e-19	FFCP PHASE1:Hg19::chr14:91270270..91270281,-	p@chr14:91270270..91270281, -
1.15e-19	FFCP PHASE2:Hg19::chr14:91270270..91270281,-	p@chr14:91270270..91270281, -
2.44e-19	FFCP PHASE1:Hg19::chr12:52306196..52306215,+	p6@ACVRL1
2.44e-19	FFCP PHASE2:Hg19::chr12:52306196..52306215,+	p6@ACVRL1
3.27e-19	FFCP PHASE1:Hg19::chr3:43538305..43538325,-	p@chr3:43538305..43538325, -
3.27e-19	FFCP PHASE2:Hg19::chr3:43538305..43538325,-	p@chr3:43538305..43538325, -
4.64e-19	FFCP PHASE2:Hg19::chr17:171147..171161,+	p@chr17:171147..171161, +
4.64e-19	FFCP PHASE1:Hg19::chr17:171147..171161,+	p@chr17:171147..171161, +
5.39e-19	FFCP PHASE2:Hg19::chr1:22211913..22211920,+	p@chr1:22211913..22211920, +
5.39e-19	FFCP PHASE1:Hg19::chr1:22211913..22211920,+	p@chr1:22211913..22211920, +
1.99e-18	FFCP PHASE1:Hg19::chr7:27219833..27219845,-	p7@HOXA10
1.99e-18	FFCP PHASE2:Hg19::chr7:27219833..27219845,-	p7@HOXA10
2.69e-18	FFCP PHASE1:Hg19::chr1:32041957..32041990,+	p3@TINAGL1
2.69e-18	FFCP PHASE2:Hg19::chr1:32041957..32041990,+	p3@TINAGL1
4.1e-18	FFCP PHASE2:Hg19::chr6:132270228..132270243,-	p17@CTGF
4.1e-18	FFCP PHASE1:Hg19::chr6:132270228..132270243,-	p17@CTGF
5.7e-18	FFCP PHASE1:Hg19::chr11:940729..940745,+	p5@AP2A2
5.7e-18	FFCP PHASE2:Hg19::chr11:940729..940745,+	p5@AP2A2
6.5e-18	FFCP PHASE1:Hg19::chr19:42007093..42007107,-	p@chr19:42007093..42007107, -
6.5e-18	FFCP PHASE2:Hg19::chr19:42007093..42007107,-	p@chr19:42007093..42007107, -
6.99e-18	FFCP PHASE1:Hg19::chrX:128781853..128781866,-	p@chrX:128781853..128781866, -
6.99e-18	FFCP PHASE2:Hg19::chrX:128781853..128781866,-	p@chrX:128781853..128781866, -
1.24e-17	FFCP PHASE2:Hg19::chr16:86604624..86604648,+	p@chr16:86604624..86604648, +
1.24e-17	FFCP PHASE1:Hg19::chr16:86604624..86604648,+	p@chr16:86604624..86604648, +

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