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Coexpression cluster:C919

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Full id: C919_Neurons_Neural_parietal_Astrocyte_duodenum_occipital_temporal



Phase1 CAGE Peaks

Hg19::chr17:49124024..49124036,-p10@SPAG9
Hg19::chr2:105467904..105467924,-p1@ENST00000413121
p1@ENST00000443988
p1@ENST00000458253
p1@uc002tck.1
Hg19::chr2:105470562..105470582,+p5@POU3F3
Hg19::chr2:105470599..105470610,+p6@POU3F3
Hg19::chr6:123101428..123101450,+p@chr6:123101428..123101450
+
Hg19::chr6:98264524..98264558,+p@chr6:98264524..98264558
+
Hg19::chr6:99282570..99282591,+p4@POU3F2
Hg19::chr6:99282592..99282616,+p3@POU3F2
Hg19::chr6:99283040..99283063,+p5@POU3F2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0021985neurohypophysis development0.00635789657521692
GO:0021979hypothalamus cell differentiation0.00635789657521692
GO:0021854hypothalamus development0.00635789657521692
GO:0014002astrocyte development0.00635789657521692
GO:0021761limbic system development0.00826417063337453
GO:0048708astrocyte differentiation0.00826417063337453
GO:0021983pituitary gland development0.00826417063337453
GO:0040018positive regulation of multicellular organism growth0.00826417063337453
GO:0021536diencephalon development0.00826417063337453
GO:0021782glial cell development0.00826417063337453
GO:0040014regulation of multicellular organism growth0.0108960427314122
GO:0045927positive regulation of growth0.0108960427314122
GO:0035264multicellular organism growth0.0108960427314122
GO:0001669acrosome0.0108960427314122
GO:0050770regulation of axonogenesis0.0110167854537886
GO:0010001glial cell differentiation0.0115194470888124
GO:0035270endocrine system development0.0123365310940337
GO:0042063gliogenesis0.0127094295453305
GO:0050767regulation of neurogenesis0.0127094295453305
GO:0030900forebrain development0.0139182114861477
GO:0048732gland development0.0139182114861477
GO:0007409axonogenesis0.0308770916361527
GO:0048667neuron morphogenesis during differentiation0.0308770916361527
GO:0048812neurite morphogenesis0.0308770916361527
GO:0000904cellular morphogenesis during differentiation0.0308770916361527
GO:0031175neurite development0.0308770916361527
GO:0008544epidermis development0.0308770916361527
GO:0007420brain development0.0308770916361527
GO:0045595regulation of cell differentiation0.0308770916361527
GO:0007398ectoderm development0.0308770916361527
GO:0048666neuron development0.0315146554353818
GO:0005764lysosome0.0335936865800335
GO:0040008regulation of growth0.0335936865800335
GO:0000323lytic vacuole0.0335936865800335
GO:0032990cell part morphogenesis0.0335936865800335
GO:0030030cell projection organization and biogenesis0.0335936865800335
GO:0048858cell projection morphogenesis0.0335936865800335
GO:0030182neuron differentiation0.0335936865800335
GO:0007283spermatogenesis0.0335936865800335
GO:0048232male gamete generation0.0335936865800335
GO:0005773vacuole0.0339849946966792
GO:0008284positive regulation of cell proliferation0.0339849946966792
GO:0007417central nervous system development0.0339849946966792
GO:0050793regulation of developmental process0.0339849946966792
GO:0048699generation of neurons0.0340715777262218
GO:0022008neurogenesis0.0355757701702134
GO:0007276gamete generation0.0355757701702134
GO:0009888tissue development0.040220148346657
GO:0019953sexual reproduction0.040685094257863
GO:0042802identical protein binding0.0460402262403028



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
neural cell8.55e-1025
neurectodermal cell5.28e-0859
oligodendrocyte8.82e-077
macroglial cell8.82e-077
astrocyte8.82e-077
oligodendrocyte precursor cell8.82e-077
Uber Anatomy
Ontology termp-valuen
central nervous system1.19e-4582
regional part of nervous system2.91e-4594
nervous system2.91e-4594
neural tube1.19e-3857
neural rod1.19e-3857
future spinal cord1.19e-3857
neural keel1.19e-3857
brain6.36e-3769
future brain6.36e-3769
regional part of brain3.33e-3559
neurectoderm3.71e-3290
ectoderm1.98e-31173
presumptive ectoderm1.98e-31173
neural plate5.27e-3086
presumptive neural plate5.27e-3086
ectoderm-derived structure1.91e-29169
regional part of forebrain1.04e-2841
forebrain1.04e-2841
future forebrain1.04e-2841
telencephalon1.11e-2734
anterior neural tube1.44e-2742
gray matter1.85e-2734
brain grey matter1.85e-2734
regional part of telencephalon8.09e-2733
cerebral hemisphere5.44e-2632
anterior region of body1.91e-25129
craniocervical region1.91e-25129
head7.71e-25123
adult organism1.81e-23115
pre-chordal neural plate1.80e-2261
cerebral cortex1.55e-2025
pallium1.55e-2025
regional part of cerebral cortex6.62e-1822
neocortex2.42e-1620
posterior neural tube4.85e-1215
chordal neural plate4.85e-1215
segmental subdivision of nervous system1.18e-1013
segmental subdivision of hindbrain6.99e-1012
hindbrain6.99e-1012
presumptive hindbrain6.99e-1012
organ part1.85e-09219
basal ganglion2.22e-089
nuclear complex of neuraxis2.22e-089
aggregate regional part of brain2.22e-089
collection of basal ganglia2.22e-089
cerebral subcortex2.22e-089
nucleus of brain2.43e-089
neural nucleus2.43e-089
regional part of metencephalon1.10e-079
metencephalon1.10e-079
future metencephalon1.10e-079
tube2.65e-07194
cavitated compound organ3.32e-0732
embryo6.90e-07612
telencephalic nucleus7.07e-077
organism subdivision9.91e-07365


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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