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{{Coexpression_clusters
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|full_id=C1849_anaplastic_cord_hairy_mycosis_adult_myeloma_NK
|id=C1849
}}

Latest revision as of 11:53, 17 September 2013


Full id: C1849_anaplastic_cord_hairy_mycosis_adult_myeloma_NK



Phase1 CAGE Peaks

Hg19::chr1:212873200..212873230,-p5@BATF3
Hg19::chr1:212873267..212873332,-p1@BATF3
Hg19::chr3:118905564..118905595,+p4@UPK1B
Hg19::chr3:16563124..16563137,+p@chr3:16563124..16563137
+
Hg19::chr3:186150363..186150372,+p@chr3:186150363..186150372
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen
chorionic membrane mesenchymal stem cell2.78e-203
circulating cell7.28e-116
antibody secreting cell1.18e-071
plasma cell1.18e-071
plasmablast1.18e-071
Uber Anatomy
Ontology termp-valuen
acellular anatomical structure2.78e-203
egg chorion2.78e-203
chorion5.08e-157
extraembryonic structure1.06e-1224
primary palate mesenchyme5.70e-081
pneumatized bone5.70e-081
subdivision of skeleton5.70e-081
intramembranous bone5.70e-081
head bone5.70e-081
dermal bone5.70e-081
irregular bone5.70e-081
mesenchyme derived from head neural crest5.70e-081
facial mesenchyme5.70e-081
head or neck bone5.70e-081
embryonic nasal process5.70e-081
cranial neural crest5.70e-081
roof of mouth5.70e-081
mesenchyme of upper jaw5.70e-081
mesenchyme from rhombencephalic neural crest5.70e-081
membrane bone5.70e-081
pharyngeal arch mesenchymal region5.70e-081
1st arch mesenchyme5.70e-081
1st arch maxillary mesenchyme5.70e-081
1st arch mesenchyme from neural crest5.70e-081
pharyngeal arch mesenchyme from neural crest5.70e-081
maxillary process mesenchyme5.70e-081
maxilla5.70e-081
dermatocranium5.70e-081
skeleton of upper jaw5.70e-081
upper jaw region5.70e-081
frontonasal prominence5.70e-081
premaxilla5.70e-081
primary palate5.70e-081
pharyngeal arch 15.70e-081
dermal skeleton5.70e-081
entire pharyngeal arch associated mesenchyme5.70e-081
maxillary prominence5.70e-081
1st arch maxillary component5.70e-081
skeleton5.70e-081
medial nasal prominence5.70e-081
maxillary process mesenchyme from neural crest5.70e-081
rhombencephalon neural crest5.70e-081
1st arch maxillary mesenchyme from neural crest5.70e-081
extraembryonic membrane1.41e-0714
membranous layer1.41e-0714
tonsil1.87e-071
mucosa-associated lymphoid tissue1.87e-071
lymphoid tissue1.87e-071
tonsillar ring1.87e-071
thymus2.84e-074
hemolymphoid system gland2.84e-074
thymic region2.84e-074
pharyngeal gland2.84e-074
thymus primordium2.84e-074
Disease
Ontology termp-valuen
non-Hodgkin lymphoma3.32e-081
cutaneous T cell lymphoma3.32e-081
mycosis fungoides3.32e-081
vascular disease7.97e-081
ischemia7.97e-081
extrinsic cardiomyopathy7.97e-081
myocardial ischemia7.97e-081
myocardial infarction7.97e-081


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.737422
MA0004.11.51734
MA0006.11.14863
MA0007.10.606704
MA0009.11.11255
MA0014.11.9468
MA0017.10.496101
MA0019.10.784036
MA0024.11.00439
MA0025.11.24931
MA0027.12.73598
MA0028.10.470679
MA0029.11.02437
MA0030.11.01252
MA0031.10.945567
MA0038.10.736268
MA0040.11.03042
MA0041.10.64667
MA0042.10.612397
MA0043.11.11288
MA0046.11.10134
MA0048.10.195817
MA0050.10.613347
MA0051.11.73592
MA0052.11.03442
MA0055.10.288856
MA0056.10
MA0057.10.189508
MA0058.13.29768
MA0059.12.23433
MA0060.10.321781
MA0061.10.291022
MA0063.10
MA0066.10.736721
MA0067.11.43651
MA0068.10.247962
MA0069.11.09737
MA0070.11.08584
MA0071.10.695094
MA0072.11.0812
MA0073.10.0469445
MA0074.10.730989
MA0076.10.540943
MA0077.11.07324
MA0078.10.836493
MA0081.10.522409
MA0083.12.53033
MA0084.11.62584
MA0087.11.07867
MA0088.10.412364
MA0089.10
MA0090.11.36977
MA0091.10.629594
MA0092.10.588959
MA0093.12.99362
MA0095.10
MA0098.10
MA0100.10.750974
MA0101.12.02769
MA0103.10.442769
MA0105.10.175503
MA0106.10.779931
MA0107.11.74965
MA0108.20.94238
MA0109.10
MA0111.11.40074
MA0113.10.797251
MA0114.10.372523
MA0115.11.35895
MA0116.11.76306
MA0117.11.1512
MA0119.10.504689
MA0122.11.17777
MA0124.11.31673
MA0125.11.23103
MA0130.10
MA0131.10.855546
MA0132.10
MA0133.10
MA0135.11.14377
MA0136.10.743749
MA0139.10.277033
MA0140.10.692258
MA0141.10.520334
MA0142.10.912455
MA0143.10.797437
MA0144.13.47082
MA0145.10.143698
MA0146.10.333008
MA0147.10.386018
MA0148.10.653474
MA0149.10.681935
MA0062.20.284987
MA0035.20.691506
MA0039.21.92202
MA0138.20.837782
MA0002.20.30855
MA0137.23.09133
MA0104.21.54865
MA0047.20.767096
MA0112.20.136971
MA0065.20.146576
MA0150.10.550239
MA0151.10
MA0152.10.69926
MA0153.11.21379
MA0154.10.172764
MA0155.10.130813
MA0156.10.480289
MA0157.10.883854
MA0158.10
MA0159.10.386729
MA0160.10.669748
MA0161.10
MA0162.11.72541
MA0163.10.680296
MA0164.10.810347
MA0080.20.456437
MA0018.20.781393
MA0099.20.699641
MA0079.21.27276
MA0102.21.66336
MA0258.10.345771
MA0259.10.395396
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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