MCL coexpression mm9:718: Difference between revisions
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{{MCL_coexpression_mm9 | 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processing and presentation of peptide antigen via MHC class I;0.00724505164829319;21356,14964!GO:0048002;antigen processing and presentation of peptide antigen;0.00924049014773828;21356,14964!GO:0019882;antigen processing and presentation;0.00924049014773828;21356,14964!GO:0050823;peptide antigen stabilization;0.00924049014773828;21356!GO:0045082;positive regulation of interleukin-10 biosynthetic process;0.00924049014773828;12051!GO:0002312;B cell activation during immune response;0.00924049014773828;12051!GO:0045074;regulation of interleukin-10 biosynthetic process;0.00924049014773828;12051!GO:0002315;marginal zone B cell differentiation;0.00924049014773828;12051!GO:0042536;negative regulation of tumor necrosis factor biosynthetic process;0.00924049014773828;12051!GO:0002313;mature B cell differentiation during immune response;0.00924049014773828;12051!GO:0042091;interleukin-10 biosynthetic process;0.00924049014773828;12051!GO:0050822;peptide stabilization;0.00924049014773828;21356!GO:0002266;follicular dendritic cell activation;0.0138580772896944;12051!GO:0002268;follicular dendritic cell differentiation;0.0138580772896944;12051!GO:0042832;defense response to protozoan;0.0138580772896944;12051!GO:0002335;mature B cell differentiation;0.0138580772896944;12051!GO:0001562;response to protozoan;0.0195605928569083;12051!GO:0045064;T-helper 2 cell differentiation;0.0211089724546047;12051!GO:0019883;antigen processing and presentation of endogenous antigen;0.0211089724546047;21356!GO:0002483;antigen processing and presentation of endogenous peptide antigen;0.0211089724546047;21356!GO:0019885;antigen processing and presentation of endogenous peptide antigen via MHC class I;0.0211089724546047;21356!GO:0032613;interleukin-10 production;0.0221431809126398;12051!GO:0019730;antimicrobial humoral response;0.0221431809126398;12051!GO:0042534;regulation of tumor necrosis factor biosynthetic process;0.0221431809126398;12051!GO:0042092;T-helper 2 type immune response;0.0221431809126398;12051!GO:0042533;tumor necrosis factor biosynthetic process;0.0221431809126398;12051!GO:0002376;immune system process;0.0221431809126398;12051,21356,14964!GO:0002467;germinal center formation;0.0221431809126398;12051!GO:0017127;cholesterol transporter activity;0.0221431809126398;59045!GO:0032729;positive regulation of interferon-gamma production;0.0221431809126398;12051!GO:0015248;sterol transporter activity;0.0221431809126398;59045!GO:0048536;spleen development;0.0221431809126398;12051!GO:0002294;CD4-positive, alpha-beta T cell differentiation during immune response;0.0221431809126398;12051!GO:0002292;T cell differentiation during immune response;0.0221431809126398;12051!GO:0042093;T-helper cell differentiation;0.0221431809126398;12051!GO:0002285;lymphocyte activation during immune response;0.0221431809126398;12051!GO:0015485;cholesterol binding;0.0221431809126398;59045!GO:0042088;T-helper 1 type immune response;0.0221431809126398;12051!GO:0002293;alpha-beta T cell differentiation during immune response;0.0221431809126398;12051!GO:0002286;T cell activation during immune response;0.0221431809126398;12051!GO:0006518;peptide metabolic process;0.0221431809126398;21356!GO:0002366;leukocyte activation during immune response;0.0221431809126398;12051!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0221431809126398;12051!GO:0032649;regulation of interferon-gamma production;0.0221431809126398;12051!GO:0002263;cell activation during immune response;0.0221431809126398;12051!GO:0042036;negative regulation of cytokine biosynthetic process;0.0240640605136774;12051!GO:0004179;membrane alanyl aminopeptidase activity;0.0248450617340259;16790!GO:0043367;CD4-positive, alpha beta T cell differentiation;0.0248450617340259;12051!GO:0016284;alanine aminopeptidase activity;0.0248450617340259;16790!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.028764067195156;12051!GO:0032934;sterol binding;0.0297795669440622;59045!GO:0006700;C21-steroid hormone biosynthetic process;0.0297795669440622;59045!GO:0032640;tumor necrosis factor production;0.0312986652257444;12051!GO:0032609;interferon-gamma production;0.0321650672965152;12051!GO:0042612;MHC class I protein complex;0.0321650672965152;14964!GO:0008630;DNA damage response, signal transduction resulting in induction of apoptosis;0.0329699268078963;12051!GO:0008207;C21-steroid hormone metabolic process;0.0329699268078963;59045!GO:0001819;positive regulation of cytokine production;0.0380974731358029;12051!GO:0046632;alpha-beta T cell differentiation;0.0393168040238089;12051!GO:0017148;negative regulation of translation;0.0459903513050557;12051!GO:0031327;negative regulation of cellular biosynthetic process;0.0470368520117554;12051!GO:0042611;MHC protein complex;0.0472862331522246;14964!GO:0005770;late endosome;0.0472862331522246;59045!|ontology_enrichment_celltype=CL:0000219!1.44e-09!54;CL:0002320!2.12e-09!46;CL:0000134!2.12e-09!46|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0004119!3.82e-15!118;UBERON:0000925!3.82e-15!118;UBERON:0006595!3.82e-15!118;UBERON:0001007!1.66e-14!116;UBERON:0001555!1.66e-14!116;UBERON:0007026!1.66e-14!116;UBERON:0004921!1.83e-13!114;UBERON:0002193!1.11e-11!48;UBERON:0002405!1.11e-11!48;UBERON:0002390!4.82e-10!45;UBERON:0003061!4.82e-10!45;UBERON:0002384!2.12e-09!46;UBERON:0004923!2.75e-09!24;UBERON:0000490!8.16e-09!66;UBERON:0000160!2.22e-08!31;UBERON:0000344!2.61e-08!15;UBERON:0003929!3.28e-08!55;UBERON:0005911!1.78e-07!69;UBERON:0005409!1.81e-07!47;UBERON:0002371!3.60e-07!16;UBERON:0001242!4.14e-07!13;UBERON:0000060!4.14e-07!13;UBERON:0001262!4.14e-07!13;UBERON:0004786!4.14e-07!13;UBERON:0002204!9.52e-07!32|tfbs_overrepresentation_for_novel_motifs=0.860199,0.883225,0.297937,0.360062,0.580303,0.373426,0.458558,0.392928,0.411053,1.53832,0.417132,0.447169,0.124608,0.470194,1.15381,0,0.656089,0.19356,0.113609,0.205418,0.26524,0.60924,0.469335,1.094,0.822446,1.24179,0.709649,1.01819,0.67135,0.572447,0.379806,0.754912,0.560002,0.31333,0.614653,0.0351598,0.184038,1.12869,0.166348,0.143746,0.196807,0.38461,0.56316,0.617704,0.434259,1.6507,0.578773,0.407653,0.772185,0.677281,0.639101,0.522137,0.550735,0.894161,0.911367,0.47699,0.249055,0.435119,0.68053,0.47505,0.735292,0.531188,0.854737,1.52021,0.487593,1.60248,1.04613,1.3932,0.730718,1.24673,0.76885,0.404236,0.356247,0.944464,0.320434,0.0893951,0.0942164,2.38336,0.718494,0.268962,0.129727,0.673009,0.529804,0.119727,0.830765,0.538155,0.182066,0.271714,0.583509,1.55487,1.11522,0.835661,0.767462,0.205117,0.163126,0.455999,0.122617,0.770215,0.57902,0.234357,0.541671,0.754637,0.87698,0.639679,0.638654,1.77029,0.696857,0.403887,0.750985,0.736223,0.845852,0.878738,0.26996,1.08155,1.12221,0.195318,0.409202,0.363536,1.58124,0.181004,0.949798,0.607824,0.498153,0.566919,1.17594,0.722111,0.466292,0.760818,1.04463,0.59809,0.86025,0.353344,1.01535,0.48999,1.14365,0.33206,0.877308,0.385921,1.09487,1.92247,1.5231,1.0508,0.509663,0.765172,0.632358,0.385031,0.581788,1.88287,0.331322,0.58382,0.0806411,0.305197,0.895708,0.46758,0.489108,0.976367,0.523103,0.224422,0.319291,0.328917,1.1043,0.829923,0.722546,0.841258,0.629147,0.482049,0.53929,0.445669,0.19482|tfbs_overrepresentation_jaspar=MA0003.1;1.53513,MA0004.1;0.360508,MA0006.1;0.604851,MA0007.1;0.346734,MA0009.1;0.780842,MA0014.1;2.6738,MA0017.1;0.233089,MA0019.1;0.603066,MA0024.1;0.737933,MA0025.1;1.01089,MA0027.1;2.42079,MA0028.1;2.57895,MA0029.1;0.716673,MA0030.1;0.723093,MA0031.1;0.688336,MA0038.1;0.496338,MA0040.1;0.79313,MA0041.1;0.291712,MA0042.1;0.279998,MA0043.1;0.875991,MA0046.1;0.816137,MA0048.1;0.236433,MA0050.1;2.71608,MA0051.1;4.34423,MA0052.1;0.801048,MA0055.1;2.04176,MA0056.1;0,MA0057.1;0.471918,MA0058.1;0.273976,MA0059.1;0.28489,MA0060.1;0.8754,MA0061.1;2.95057,MA0063.1;0,MA0066.1;0.485868,MA0067.1;1.12095,MA0068.1;0.484739,MA0069.1;0.801381,MA0070.1;0.791856,MA0071.1;1.02422,MA0072.1;0.783532,MA0073.1;1.78317,MA0074.1;0.451832,MA0076.1;3.65654,MA0077.1;0.762273,MA0078.1;0.536502,MA0081.1;0.305576,MA0083.1;0.875209,MA0084.1;1.44691,MA0087.1;0.832758,MA0088.1;0.0379749,MA0089.1;0,MA0090.1;0.329158,MA0091.1;0.372635,MA0092.1;0.329444,MA0093.1;0.226349,MA0095.1;0,MA0098.1;0,MA0100.1;0.440912,MA0101.1;2.21397,MA0103.1;0.67982,MA0105.1;2.13991,MA0106.1;0.543967,MA0107.1;4.46719,MA0108.2;0.625209,MA0109.1;0,MA0111.1;0.90605,MA0113.1;0.516916,MA0114.1;0.167085,MA0115.1;0.878749,MA0116.1;0.604438,MA0117.1;0.846964,MA0119.1;0.293392,MA0122.1;0.866511,MA0124.1;1.06819,MA0125.1;0.994853,MA0130.1;0,MA0131.1;1.45836,MA0132.1;0,MA0133.1;0,MA0135.1;0.911905,MA0136.1;1.18666,MA0139.1;0.121562,MA0140.1;0.440804,MA0141.1;0.259554,MA0142.1;0.674191,MA0143.1;0.53259,MA0144.1;0.169559,MA0145.1;0.163161,MA0146.1;0.412111,MA0147.1;0.530496,MA0148.1;0.375491,MA0149.1;0.2978,MA0062.2;3.53266,MA0035.2;0.44524,MA0039.2;1.66029,MA0138.2;0.590987,MA0002.2;0.781868,MA0137.2;0.257017,MA0104.2;0.418613,MA0047.2;0.495607,MA0112.2;0.163154,MA0065.2;0.163769,MA0150.1;0.916186,MA0151.1;0,MA0152.1;0.495709,MA0153.1;0.92832,MA0154.1;0.501928,MA0155.1;0.732931,MA0156.1;1.28579,MA0157.1;0.642984,MA0158.1;0,MA0159.1;0.550545,MA0160.1;0.378276,MA0161.1;0,MA0162.1;1.7893,MA0163.1;4.74746,MA0164.1;0.471016,MA0080.2;0.237846,MA0018.2;0.480226,MA0099.2;0.584892,MA0079.2;2.09889,MA0102.2;1.49914,MA0258.1;0.473611,MA0259.1;0.170828,MA0442.1;0}} 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| |||
|coexpression_dpi_cluster_scores_median=-0.322940775228237,1.16223949558923,1.11331230516791,0.794754493839761,0.805203483742826,0.535563142958274,0.526886264685519,0.313392366994083,0.563867322524815,0.586781764559116,0.240538330759363,0.347830703864758,0.295184111653205,0.289942536881565,0.225717413463866,0.209033458212431,0.0530938610966532,0.529079920076508,0.480777333207886,0.488610381338316,0.173762818451391,0.102928268328245,0.0161163929378376,0.696006617169758,0.682129543106145,1.00050182820942,0.968990812017521,0.903380897956433,0.527397640040864,0.432677759547794,0.687206930995706,-0.15932069516867,-0.132196572102655,-0.396878400286204,0.141093071512008,0.119382855106078,0.129519340420362,0.485261533921188,0.425331534244921,0.401689643711855,0.558807346020153,0.484338013625609,0.406828130465295,0.121624461055623,0.12115814066404,0.0367721768778499,0.520708126382696,-0.012584527638734,0.0911386176635214,0.0264221460779739,0.0150700687990852,0.0194766960963774,0.570100037120504,0.381723174178618,0.279405943886249,0.130519021007368,0.275984154740294,0.192295748354153,-0.243751173273545,-0.296816906336714,-0.268969191517448,0.128192966471069,0.262321882429918,1.02812149689223,1.13439213630696,1.07845945054984,0.577686988032812,0.489818919571237,-0.418970666031976,-0.401016239325791,-0.46740040521293,-0.173803142783802,-0.0393700885622726,-0.450274122857178,-0.496105795894158,-0.494361686739808,0.0253311190416989,-0.039870483527631,-0.11161852400041,-0.285060333845381,-0.25101616788944,-0.305826161359844,0.0202141534527503,-0.162024853887092,-0.0638952056626579,-0.112205925525966,-0.198155386477547,-0.191595873867153,-0.0185808803476532,0.220832934520525,0.337893608714659,0.142067890208248,0.287296386957061,0.263401678768948,0.409711243895285,0.306512881751814,0.245319937232506,0.0406982434809034,-0.0785653184016844,-0.0300136904558658,-0.278304922638901,0.0698778845826524,0.182776171182224,0.0454983957924694,0.124055892819796,0.144081142270854,0.17968464273652,0.445388363878338,0.715692615389101,0.327071502553842,-0.173600613869697,-0.0445304616048878,-0.0658753733200988,-0.0702120659127541,-0.0398326924157973,0.126126444276939,0.119347546204447,0.445585477140799,0.280862025453933,-0.0640348366488863,0.0904408413203979,0.0889482512879071,0.316320028811298,-0.17862720561564,-0.235603698307959,0.599249877875856,0.244062074348666,0.105665101787864,0.175113972789534,-0.22009083261858,-0.115396449762576,-0.366433279443312,-0.0736455606455052,-0.170012558041761,-0.145636516443259,-0.167816773749522,-0.000153607781629501,0.189886424046123,0.207605817727889,0.179591118301681,-0.285974807451106,-0.23449545242898,-0.254169434355955,-0.272954172231404,-0.165364337330791,-0.220877703134071,-0.194443209633789,0.0357935723557504,-0.212446600135168,-0.245402212568921,-0.173629202459294,-0.18299342166421,-0.212914358874343,-0.0931166001799723,-0.0946515252107376,-0.227990878726968,0.0571875937985628,0.100839397070023,0.178908134469417,-0.262702016850095,-0.201213557363065,-0.205600602953963,-0.223420257988113,-0.197419942653998,-0.180755142352033,-0.176797004194822,-0.0953151694007625,-0.152276045781628,-0.204939266110416,-0.06226214706134,0.039100328926437,0.0163192114874242,0.152536766906626,0.0788579988614524,-0.141178426444221,-0.239519552322904,0.671025923269581,0.413521917050989,-0.299127175503826,-0.259376891432199,-0.130980308672512,-0.0566767777517536,0.0691577699932938,0.195954560527908,0.424421089451098,0.200729598514492,0.171024990068464,0.302217087753911,0.253476454785293,0.539045275375907,0.390132291196717,0.408243843538502,-0.135400574887966,-0.201616805841869,-0.0456045355087266,-0.175854119556364,-0.168497226489457,-0.14512418006651,-0.102184008883188,0.0416676437418912,0.00598127538496862,0.0105969685883585,0.345660248077897,-0.174643496060246,-0.102749089419275,-0.104301807709954,-0.0875946988526715,-0.013077919019898,-0.0173552776221787,0.100147224870591,0.048744979427119,0.0220647415037151,0.165789989134354,0.331477088778176,0.14046490203967,0.283567191222897,0.143663153001951,0.166258323546515,0.445434919242952,-0.28772102060633,-0.287891794269748,-0.261598993501514,-0.231778014114481,-0.0331273529480889,0.0808263689673718,0.138797963093395,0.061176289053337,0.124565184840339,0.119855818157668,0.27667005903154,0.416656344216862,0.321889825324136,1.09370625791127,1.25188632904116,0.372784281782705,0.398547272667919,-0.130684102476437,-0.16114077530317,-0.0516086275995634,0.0252038347411721,-0.0893905172288678,-0.121033675554239,-0.185918861992666,-0.0807664240790342,0.00830313908819613,0.0875355783090614,-0.0341675323055637,-0.060643787173278,-0.110093866310642,-0.166002542120273,0.24350686463085,-0.0329240313557396,-0.064934887355293,0.300576231445524,0.200278270259449,-0.172816558444662,-0.264665797555029,-0.206868679274177,-0.0222391668451346,-0.0738509585301929,0.0863645730715386,-0.0980959470547676,-0.101063467347098,0.0932024567748566,0.115781258599469,0.0610171443438726,0.0103840549824213,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| |||
|gostat_on_MCL_coexpression=GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00724505164829319;21356,14964!GO:0048002;antigen processing and presentation of peptide antigen;0.00924049014773828;21356,14964!GO:0019882;antigen processing and presentation;0.00924049014773828;21356,14964!GO:0050823;peptide antigen stabilization;0.00924049014773828;21356!GO:0045082;positive regulation of interleukin-10 biosynthetic process;0.00924049014773828;12051!GO:0002312;B cell activation during immune response;0.00924049014773828;12051!GO:0045074;regulation of interleukin-10 biosynthetic process;0.00924049014773828;12051!GO:0002315;marginal zone B cell differentiation;0.00924049014773828;12051!GO:0042536;negative regulation of tumor necrosis factor biosynthetic process;0.00924049014773828;12051!GO:0002313;mature B cell differentiation during immune response;0.00924049014773828;12051!GO:0042091;interleukin-10 biosynthetic process;0.00924049014773828;12051!GO:0050822;peptide stabilization;0.00924049014773828;21356!GO:0002266;follicular dendritic cell activation;0.0138580772896944;12051!GO:0002268;follicular dendritic cell differentiation;0.0138580772896944;12051!GO:0042832;defense response to protozoan;0.0138580772896944;12051!GO:0002335;mature B cell differentiation;0.0138580772896944;12051!GO:0001562;response to protozoan;0.0195605928569083;12051!GO:0045064;T-helper 2 cell differentiation;0.0211089724546047;12051!GO:0019883;antigen processing and presentation of endogenous antigen;0.0211089724546047;21356!GO:0002483;antigen processing and presentation of endogenous peptide antigen;0.0211089724546047;21356!GO:0019885;antigen processing and presentation of endogenous peptide antigen via MHC class I;0.0211089724546047;21356!GO:0032613;interleukin-10 production;0.0221431809126398;12051!GO:0019730;antimicrobial humoral response;0.0221431809126398;12051!GO:0042534;regulation of tumor necrosis factor biosynthetic process;0.0221431809126398;12051!GO:0042092;T-helper 2 type immune response;0.0221431809126398;12051!GO:0042533;tumor necrosis factor biosynthetic process;0.0221431809126398;12051!GO:0002376;immune system process;0.0221431809126398;12051,21356,14964!GO:0002467;germinal center formation;0.0221431809126398;12051!GO:0017127;cholesterol transporter activity;0.0221431809126398;59045!GO:0032729;positive regulation of interferon-gamma production;0.0221431809126398;12051!GO:0015248;sterol transporter activity;0.0221431809126398;59045!GO:0048536;spleen development;0.0221431809126398;12051!GO:0002294;CD4-positive, alpha-beta T cell differentiation during immune response;0.0221431809126398;12051!GO:0002292;T cell differentiation during immune response;0.0221431809126398;12051!GO:0042093;T-helper cell differentiation;0.0221431809126398;12051!GO:0002285;lymphocyte activation during immune response;0.0221431809126398;12051!GO:0015485;cholesterol binding;0.0221431809126398;59045!GO:0042088;T-helper 1 type immune response;0.0221431809126398;12051!GO:0002293;alpha-beta T cell differentiation during immune response;0.0221431809126398;12051!GO:0002286;T cell activation during immune response;0.0221431809126398;12051!GO:0006518;peptide metabolic process;0.0221431809126398;21356!GO:0002366;leukocyte activation during immune response;0.0221431809126398;12051!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0221431809126398;12051!GO:0032649;regulation of interferon-gamma production;0.0221431809126398;12051!GO:0002263;cell activation during immune response;0.0221431809126398;12051!GO:0042036;negative regulation of cytokine biosynthetic process;0.0240640605136774;12051!GO:0004179;membrane alanyl aminopeptidase activity;0.0248450617340259;16790!GO:0043367;CD4-positive, alpha beta T cell differentiation;0.0248450617340259;12051!GO:0016284;alanine aminopeptidase activity;0.0248450617340259;16790!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.028764067195156;12051!GO:0032934;sterol binding;0.0297795669440622;59045!GO:0006700;C21-steroid hormone biosynthetic process;0.0297795669440622;59045!GO:0032640;tumor necrosis factor production;0.0312986652257444;12051!GO:0032609;interferon-gamma production;0.0321650672965152;12051!GO:0042612;MHC class I protein complex;0.0321650672965152;14964!GO:0008630;DNA damage response, signal transduction resulting in induction of apoptosis;0.0329699268078963;12051!GO:0008207;C21-steroid hormone metabolic process;0.0329699268078963;59045!GO:0001819;positive regulation of cytokine production;0.0380974731358029;12051!GO:0046632;alpha-beta T cell differentiation;0.0393168040238089;12051!GO:0017148;negative regulation of translation;0.0459903513050557;12051!GO:0031327;negative regulation of cellular biosynthetic process;0.0470368520117554;12051!GO:0042611;MHC protein complex;0.0472862331522246;14964!GO:0005770;late endosome;0.0472862331522246;59045! | |||
|ontology_enrichment_celltype=CL:0000219!1.44e-09!54;CL:0002320!2.12e-09!46;CL:0000134!2.12e-09!46 | |||
|ontology_enrichment_disease= | |||
|ontology_enrichment_uberon=UBERON:0004119!3.82e-15!118;UBERON:0000925!3.82e-15!118;UBERON:0006595!3.82e-15!118;UBERON:0001007!1.66e-14!116;UBERON:0001555!1.66e-14!116;UBERON:0007026!1.66e-14!116;UBERON:0004921!1.83e-13!114;UBERON:0002193!1.11e-11!48;UBERON:0002405!1.11e-11!48;UBERON:0002390!4.82e-10!45;UBERON:0003061!4.82e-10!45;UBERON:0002384!2.12e-09!46;UBERON:0004923!2.75e-09!24;UBERON:0000490!8.16e-09!66;UBERON:0000160!2.22e-08!31;UBERON:0000344!2.61e-08!15;UBERON:0003929!3.28e-08!55;UBERON:0005911!1.78e-07!69;UBERON:0005409!1.81e-07!47;UBERON:0002371!3.60e-07!16;UBERON:0001242!4.14e-07!13;UBERON:0000060!4.14e-07!13;UBERON:0001262!4.14e-07!13;UBERON:0004786!4.14e-07!13;UBERON:0002204!9.52e-07!32 | |||
}} |
Latest revision as of 15:46, 17 September 2013
Phase1 CAGE Peaks
Short description | |
---|---|
Mm9::chr11:98219716..98219771,+ | p1@Stard3 |
Mm9::chr13:24893063..24893082,+ | p1@BC005537 |
Mm9::chr15:76181104..76181175,- | p2@Sharpin |
Mm9::chr17:34056590..34056621,+ | p1@Tapbp |
Mm9::chr17:34056624..34056635,+ | p2@Tapbp |
Mm9::chr17:35400032..35400045,+ | p1@H2-D1 |
Mm9::chr5:34868446..34868518,+ | p1@Sh3bp2 |
Mm9::chr7:20408047..20408125,- | p1@Bcl3 |
Mm9::chr7:51809271..51809325,- | p1@Nr1h2 |
Mm9::chr7:86993077..86993110,- | p2@Anpep |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 0.00724505164829319 |
GO:0048002 | antigen processing and presentation of peptide antigen | 0.00924049014773828 |
GO:0019882 | antigen processing and presentation | 0.00924049014773828 |
GO:0050823 | peptide antigen stabilization | 0.00924049014773828 |
GO:0045082 | positive regulation of interleukin-10 biosynthetic process | 0.00924049014773828 |
GO:0002312 | B cell activation during immune response | 0.00924049014773828 |
GO:0045074 | regulation of interleukin-10 biosynthetic process | 0.00924049014773828 |
GO:0002315 | marginal zone B cell differentiation | 0.00924049014773828 |
GO:0042536 | negative regulation of tumor necrosis factor biosynthetic process | 0.00924049014773828 |
GO:0002313 | mature B cell differentiation during immune response | 0.00924049014773828 |
GO:0042091 | interleukin-10 biosynthetic process | 0.00924049014773828 |
GO:0050822 | peptide stabilization | 0.00924049014773828 |
GO:0002266 | follicular dendritic cell activation | 0.0138580772896944 |
GO:0002268 | follicular dendritic cell differentiation | 0.0138580772896944 |
GO:0042832 | defense response to protozoan | 0.0138580772896944 |
GO:0002335 | mature B cell differentiation | 0.0138580772896944 |
GO:0001562 | response to protozoan | 0.0195605928569083 |
GO:0045064 | T-helper 2 cell differentiation | 0.0211089724546047 |
GO:0019883 | antigen processing and presentation of endogenous antigen | 0.0211089724546047 |
GO:0002483 | antigen processing and presentation of endogenous peptide antigen | 0.0211089724546047 |
GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I | 0.0211089724546047 |
GO:0032613 | interleukin-10 production | 0.0221431809126398 |
GO:0019730 | antimicrobial humoral response | 0.0221431809126398 |
GO:0042534 | regulation of tumor necrosis factor biosynthetic process | 0.0221431809126398 |
GO:0042092 | T-helper 2 type immune response | 0.0221431809126398 |
GO:0042533 | tumor necrosis factor biosynthetic process | 0.0221431809126398 |
GO:0002376 | immune system process | 0.0221431809126398 |
GO:0002467 | germinal center formation | 0.0221431809126398 |
GO:0017127 | cholesterol transporter activity | 0.0221431809126398 |
GO:0032729 | positive regulation of interferon-gamma production | 0.0221431809126398 |
GO:0015248 | sterol transporter activity | 0.0221431809126398 |
GO:0048536 | spleen development | 0.0221431809126398 |
GO:0002294 | CD4-positive, alpha-beta T cell differentiation during immune response | 0.0221431809126398 |
GO:0002292 | T cell differentiation during immune response | 0.0221431809126398 |
GO:0042093 | T-helper cell differentiation | 0.0221431809126398 |
GO:0002285 | lymphocyte activation during immune response | 0.0221431809126398 |
GO:0015485 | cholesterol binding | 0.0221431809126398 |
GO:0042088 | T-helper 1 type immune response | 0.0221431809126398 |
GO:0002293 | alpha-beta T cell differentiation during immune response | 0.0221431809126398 |
GO:0002286 | T cell activation during immune response | 0.0221431809126398 |
GO:0006518 | peptide metabolic process | 0.0221431809126398 |
GO:0002366 | leukocyte activation during immune response | 0.0221431809126398 |
GO:0042771 | DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis | 0.0221431809126398 |
GO:0032649 | regulation of interferon-gamma production | 0.0221431809126398 |
GO:0002263 | cell activation during immune response | 0.0221431809126398 |
GO:0042036 | negative regulation of cytokine biosynthetic process | 0.0240640605136774 |
GO:0004179 | membrane alanyl aminopeptidase activity | 0.0248450617340259 |
GO:0043367 | CD4-positive, alpha beta T cell differentiation | 0.0248450617340259 |
GO:0016284 | alanine aminopeptidase activity | 0.0248450617340259 |
GO:0030330 | DNA damage response, signal transduction by p53 class mediator | 0.028764067195156 |
GO:0032934 | sterol binding | 0.0297795669440622 |
GO:0006700 | C21-steroid hormone biosynthetic process | 0.0297795669440622 |
GO:0032640 | tumor necrosis factor production | 0.0312986652257444 |
GO:0032609 | interferon-gamma production | 0.0321650672965152 |
GO:0042612 | MHC class I protein complex | 0.0321650672965152 |
GO:0008630 | DNA damage response, signal transduction resulting in induction of apoptosis | 0.0329699268078963 |
GO:0008207 | C21-steroid hormone metabolic process | 0.0329699268078963 |
GO:0001819 | positive regulation of cytokine production | 0.0380974731358029 |
GO:0046632 | alpha-beta T cell differentiation | 0.0393168040238089 |
GO:0017148 | negative regulation of translation | 0.0459903513050557 |
GO:0031327 | negative regulation of cellular biosynthetic process | 0.0470368520117554 |
GO:0042611 | MHC protein complex | 0.0472862331522246 |
GO:0005770 | late endosome | 0.0472862331522246 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
motile cell | 1.44e-09 | 54 |
connective tissue cell | 2.12e-09 | 46 |
mesenchymal cell | 2.12e-09 | 46 |
Ontology term | p-value | n |
---|---|---|
endoderm-derived structure | 3.82e-15 | 118 |
endoderm | 3.82e-15 | 118 |
presumptive endoderm | 3.82e-15 | 118 |
digestive system | 1.66e-14 | 116 |
digestive tract | 1.66e-14 | 116 |
primitive gut | 1.66e-14 | 116 |
subdivision of digestive tract | 1.83e-13 | 114 |
hemolymphoid system | 1.11e-11 | 48 |
immune system | 1.11e-11 | 48 |
hematopoietic system | 4.82e-10 | 45 |
blood island | 4.82e-10 | 45 |
connective tissue | 2.12e-09 | 46 |
organ component layer | 2.75e-09 | 24 |
unilaminar epithelium | 8.16e-09 | 66 |
intestine | 2.22e-08 | 31 |
mucosa | 2.61e-08 | 15 |
gut epithelium | 3.28e-08 | 55 |
endo-epithelium | 1.78e-07 | 69 |
gastrointestinal system | 1.81e-07 | 47 |
bone marrow | 3.60e-07 | 16 |
intestinal mucosa | 4.14e-07 | 13 |
anatomical wall | 4.14e-07 | 13 |
wall of intestine | 4.14e-07 | 13 |
gastrointestinal system mucosa | 4.14e-07 | 13 |
musculoskeletal system | 9.52e-07 | 32 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 1.53513 |
MA0004.1 | 0.360508 |
MA0006.1 | 0.604851 |
MA0007.1 | 0.346734 |
MA0009.1 | 0.780842 |
MA0014.1 | 2.6738 |
MA0017.1 | 0.233089 |
MA0019.1 | 0.603066 |
MA0024.1 | 0.737933 |
MA0025.1 | 1.01089 |
MA0027.1 | 2.42079 |
MA0028.1 | 2.57895 |
MA0029.1 | 0.716673 |
MA0030.1 | 0.723093 |
MA0031.1 | 0.688336 |
MA0038.1 | 0.496338 |
MA0040.1 | 0.79313 |
MA0041.1 | 0.291712 |
MA0042.1 | 0.279998 |
MA0043.1 | 0.875991 |
MA0046.1 | 0.816137 |
MA0048.1 | 0.236433 |
MA0050.1 | 2.71608 |
MA0051.1 | 4.34423 |
MA0052.1 | 0.801048 |
MA0055.1 | 2.04176 |
MA0056.1 | 0 |
MA0057.1 | 0.471918 |
MA0058.1 | 0.273976 |
MA0059.1 | 0.28489 |
MA0060.1 | 0.8754 |
MA0061.1 | 2.95057 |
MA0063.1 | 0 |
MA0066.1 | 0.485868 |
MA0067.1 | 1.12095 |
MA0068.1 | 0.484739 |
MA0069.1 | 0.801381 |
MA0070.1 | 0.791856 |
MA0071.1 | 1.02422 |
MA0072.1 | 0.783532 |
MA0073.1 | 1.78317 |
MA0074.1 | 0.451832 |
MA0076.1 | 3.65654 |
MA0077.1 | 0.762273 |
MA0078.1 | 0.536502 |
MA0081.1 | 0.305576 |
MA0083.1 | 0.875209 |
MA0084.1 | 1.44691 |
MA0087.1 | 0.832758 |
MA0088.1 | 0.0379749 |
MA0089.1 | 0 |
MA0090.1 | 0.329158 |
MA0091.1 | 0.372635 |
MA0092.1 | 0.329444 |
MA0093.1 | 0.226349 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.440912 |
MA0101.1 | 2.21397 |
MA0103.1 | 0.67982 |
MA0105.1 | 2.13991 |
MA0106.1 | 0.543967 |
MA0107.1 | 4.46719 |
MA0108.2 | 0.625209 |
MA0109.1 | 0 |
MA0111.1 | 0.90605 |
MA0113.1 | 0.516916 |
MA0114.1 | 0.167085 |
MA0115.1 | 0.878749 |
MA0116.1 | 0.604438 |
MA0117.1 | 0.846964 |
MA0119.1 | 0.293392 |
MA0122.1 | 0.866511 |
MA0124.1 | 1.06819 |
MA0125.1 | 0.994853 |
MA0130.1 | 0 |
MA0131.1 | 1.45836 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.911905 |
MA0136.1 | 1.18666 |
MA0139.1 | 0.121562 |
MA0140.1 | 0.440804 |
MA0141.1 | 0.259554 |
MA0142.1 | 0.674191 |
MA0143.1 | 0.53259 |
MA0144.1 | 0.169559 |
MA0145.1 | 0.163161 |
MA0146.1 | 0.412111 |
MA0147.1 | 0.530496 |
MA0148.1 | 0.375491 |
MA0149.1 | 0.2978 |
MA0062.2 | 3.53266 |
MA0035.2 | 0.44524 |
MA0039.2 | 1.66029 |
MA0138.2 | 0.590987 |
MA0002.2 | 0.781868 |
MA0137.2 | 0.257017 |
MA0104.2 | 0.418613 |
MA0047.2 | 0.495607 |
MA0112.2 | 0.163154 |
MA0065.2 | 0.163769 |
MA0150.1 | 0.916186 |
MA0151.1 | 0 |
MA0152.1 | 0.495709 |
MA0153.1 | 0.92832 |
MA0154.1 | 0.501928 |
MA0155.1 | 0.732931 |
MA0156.1 | 1.28579 |
MA0157.1 | 0.642984 |
MA0158.1 | 0 |
MA0159.1 | 0.550545 |
MA0160.1 | 0.378276 |
MA0161.1 | 0 |
MA0162.1 | 1.7893 |
MA0163.1 | 4.74746 |
MA0164.1 | 0.471016 |
MA0080.2 | 0.237846 |
MA0018.2 | 0.480226 |
MA0099.2 | 0.584892 |
MA0079.2 | 2.09889 |
MA0102.2 | 1.49914 |
MA0258.1 | 0.473611 |
MA0259.1 | 0.170828 |
MA0442.1 | 0 |