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MCL coexpression mm9:363

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:116661302..116661324,+p@chr10:116661302..116661324
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Mm9::chr11:109512773..109512784,+p@chr11:109512773..109512784
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Mm9::chr11:23206302..23206316,-p@chr11:23206302..23206316
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Mm9::chr11:68912249..68912254,-p@chr11:68912249..68912254
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Mm9::chr12:112680511..112680520,-p@chr12:112680511..112680520
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Mm9::chr13:81024809..81024820,-p3@ENSMUST00000161006
Mm9::chr14:122504223..122504252,+p@chr14:122504223..122504252
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Mm9::chr15:79518396..79518423,+p@chr15:79518396..79518423
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Mm9::chr17:48548802..48548850,-p@chr17:48548802..48548850
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Mm9::chr17:48548913..48548924,-p@chr17:48548913..48548924
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Mm9::chr18:3337339..3337397,-p5@Crem
Mm9::chr1:31006709..31006727,+p@chr1:31006709..31006727
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Mm9::chr1:31007100..31007109,+p@chr1:31007100..31007109
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Mm9::chr2:121275931..121275949,-p@chr2:121275931..121275949
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Mm9::chr4:109157479..109157491,+p@chr4:109157479..109157491
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Mm9::chr4:132909391..132909420,-p9@Wdtc1
Mm9::chr7:148042635..148042666,+p8@Ric8
Mm9::chr7:52494411..52494436,-p5@Cd37
Mm9::chr8:4678338..4678356,-p1@Gm7461
Mm9::chr8:4678528..4678538,+p6@ENSMUST00000105524
Mm9::chr9:108552145..108552149,+p@chr9:108552145..108552149
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0001965G-protein alpha-subunit binding0.0226799604204372



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
lymphoid lineage restricted progenitor cell4.82e-1612
hematopoietic cell6.17e-1532
hematopoietic oligopotent progenitor cell6.17e-1532
hematopoietic stem cell6.17e-1532
angioblastic mesenchymal cell6.17e-1532
hematopoietic multipotent progenitor cell6.17e-1532
T cell1.21e-1411
pro-T cell1.21e-1411
lymphocyte1.52e-1413
common lymphoid progenitor1.52e-1413
nucleate cell6.08e-1316
mature alpha-beta T cell9.08e-139
alpha-beta T cell9.08e-139
immature T cell9.08e-139
mature T cell9.08e-139
immature alpha-beta T cell9.08e-139
CD4-positive, alpha-beta T cell1.73e-118
hematopoietic lineage restricted progenitor cell3.99e-1125
intestinal epithelial cell8.04e-119
epithelial cell of alimentary canal8.04e-119
leukocyte2.46e-1017
nongranular leukocyte2.46e-1017
connective tissue cell9.28e-1046
mesenchymal cell9.28e-1046
thymocyte7.42e-096
double negative thymocyte7.42e-096
naive T cell7.42e-096
double-positive, alpha-beta thymocyte7.42e-096
CD4-positive, alpha-beta thymocyte7.42e-096
naive thymus-derived CD4-positive, alpha-beta T cell7.42e-096
DN4 thymocyte7.42e-096
DN1 thymic pro-T cell7.42e-096
DN2 thymocyte7.42e-096
DN3 thymocyte7.42e-096
immature single positive thymocyte7.42e-096
early T lineage precursor7.42e-096
mature CD4 single-positive thymocyte7.42e-096
resting double-positive thymocyte7.42e-096
double-positive blast7.42e-096
CD69-positive double-positive thymocyte7.42e-096
CD69-positive, CD4-positive single-positive thymocyte7.42e-096
CD4-positive, CD8-intermediate double-positive thymocyte7.42e-096
CD24-positive, CD4 single-positive thymocyte7.42e-096
epithelial cell1.20e-0825
columnar/cuboidal epithelial cell2.13e-087
somatic cell2.23e-08118
motile cell1.97e-0754
brush border epithelial cell2.17e-076
gut absorptive cell2.17e-076
absorptive cell2.17e-076
enterocyte2.17e-076
stem cell3.63e-0797
endo-epithelial cell4.55e-0715


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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