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UBERON:0001066

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Name:intervertebral disk
Definition:"A pad of fibrocartilage between the articular surfaces of two successive vertebral centra which has nucleus pulposus at its core." [ISBN10:0073040584, Wikipedia:Intervertebral_disk]
Xrefs:
links:

BTO:0003625
EFO:0001370
FMA:10446
GAID:105
[ 200px-Gray301.png 200px-Gray301.png]
MA:0000110
MESH:A.02.165.410
ncithesaurus:Intervertebral_Disc
OpenCyc:Mx4rv11AcpwpEbGdrcN5Y29ycA

SCTID:244570000
Synonyms: "discus intervertebralis" EXACT [FMA:10446, FMA:TA]
"intervertebral disc" EXACT []
"intervertebral fibrocartilage" RELATED [BTO:0003625]
"spinal disc" EXACT [Wikipedia:Spinal_disc]
"spinal disk" RELATED [BTO:0003625]
Comments:Taxon/Terminology notes: strictly speaking the term intervertebral disk [applies to intervertebral cartilage] whose gel-like core is nucleus puloposus, by this definition only in mammals
Alt_id: UBERON:FMA_10446-MA_0000110
Subset: uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0011135(intervertebral cartilage)



Children

part of:UBERON:0002242 (nucleus pulposus),UBERON:0004715 (annulus fibrosus disci intervertebralis)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001066 (intervertebral disk), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
1.25e-162FFCP PHASE1:Hg19::chr3:174737010..174737023,+#_f44e5139bae3beeb1f84528294b0c9f7p@chr3:174737010..174737023, +
1.25e-162FFCP PHASE2:Hg19::chr3:174737010..174737023,+#_f44e5139bae3beeb1f84528294b0c9f7p@chr3:174737010..174737023, +
3.92e-140FFCP PHASE2:Hg19::chr20:21687193..21687206,+#_d374b5525b9af3646ed9b0929b3355ccp4@PAX1
3.92e-140FFCP PHASE1:Hg19::chr20:21687193..21687206,+#_d374b5525b9af3646ed9b0929b3355ccp4@PAX1
4.22e-99FFCP PHASE2:Hg19::chr5:30104176..30104187,-#_ccecfca0a8b013df13b1f6872d22b982p@chr5:30104176..30104187, -
4.22e-99FFCP PHASE1:Hg19::chr5:30104176..30104187,-#_ccecfca0a8b013df13b1f6872d22b982p@chr5:30104176..30104187, -
1.06e-78FFCP PHASE2:Hg19::chr4:13546130..13546145,-#_64642679cccfb2997649790ac3fb5ac4p4@NKX3-2
1.06e-78FFCP PHASE1:Hg19::chr4:13546130..13546145,-#_64642679cccfb2997649790ac3fb5ac4p4@NKX3-2
2.52e-71FFCP PHASE2:Hg19::chr9:114135497..114135526,-#_976d67289c1f679bdf563ce0668ada77p@chr9:114135497..114135526, -
2.52e-71FFCP PHASE1:Hg19::chr9:114135497..114135526,-#_976d67289c1f679bdf563ce0668ada77p@chr9:114135497..114135526, -
7.4e-71FFCP PHASE1:Hg19::chr2:241897125..241897142,-#_a506377f4c19092be2dbc8c18ee4a715p@chr2:241897125..241897142, -
7.4e-71FFCP PHASE2:Hg19::chr2:241897125..241897142,-#_a506377f4c19092be2dbc8c18ee4a715p@chr2:241897125..241897142, -
6.33e-70FFCP PHASE1:Hg19::chr3:80727046..80727051,-#_4d603d1ce18b78f20202d3287e5b6105p@chr3:80727046..80727051, -
6.33e-70FFCP PHASE2:Hg19::chr3:80727046..80727051,-#_4d603d1ce18b78f20202d3287e5b6105p@chr3:80727046..80727051, -
4.8e-67FFCP PHASE2:Hg19::chr2:242004292..242004308,+#_a1bb90b83937581f00d0367a6eac70b0p15@SNED1
4.8e-67FFCP PHASE1:Hg19::chr2:242004292..242004308,+#_a1bb90b83937581f00d0367a6eac70b0p15@SNED1
1.24e-66FFCP PHASE1:Hg19::chr1:19811132..19811155,-#_ce0c2d57f5c2a03828a1fbf5b892fa6dp20@CAPZB
1.24e-66FFCP PHASE2:Hg19::chr1:19811132..19811155,-#_ce0c2d57f5c2a03828a1fbf5b892fa6dp20@CAPZB
1.26e-62FFCP PHASE1:Hg19::chr1:19778678..19778689,-#_0d6b0b4c2761d54ff3839d268d7a378ap@chr1:19778678..19778689, -
1.26e-62FFCP PHASE2:Hg19::chr1:19778678..19778689,-#_0d6b0b4c2761d54ff3839d268d7a378ap@chr1:19778678..19778689, -
1.1e-59FFCP PHASE1:Hg19::chr2:241897189..241897221,-#_5d7e02311951cfba3a6de06c447fd70cp@chr2:241897189..241897221, -
1.1e-59FFCP PHASE2:Hg19::chr2:241897189..241897221,-#_5d7e02311951cfba3a6de06c447fd70cp@chr2:241897189..241897221, -
1.55e-57FFCP PHASE1:Hg19::chr14:23574186..23574212,-#_a331fd2f1c3debf89cfcfe791a7264aap1@uc010aki.1
1.55e-57FFCP PHASE2:Hg19::chr14:23574186..23574212,-#_a331fd2f1c3debf89cfcfe791a7264aap1@uc010aki.1
4.09e-56FFCP PHASE1:Hg19::chr14:61190754..61190776,-#_b534b41da81c13ce6de7570e7dafa56dp6@SIX4
4.09e-56FFCP PHASE2:Hg19::chr14:61190754..61190776,-#_b534b41da81c13ce6de7570e7dafa56dp6@SIX4
3.74e-53FFCP PHASE1:Hg19::chr14:23574164..23574179,-#_cc7cc354c15127618342bcd8a4ed6820p3@uc010aki.1
3.74e-53FFCP PHASE2:Hg19::chr14:23574164..23574179,-#_cc7cc354c15127618342bcd8a4ed6820p3@uc010aki.1
1.15e-51FFCP PHASE1:Hg19::chr20:21687260..21687270,+#_a9ffaf2be11085ec68c5e8c4730ef5d2p3@PAX1
1.15e-51FFCP PHASE2:Hg19::chr20:21687260..21687270,+#_a9ffaf2be11085ec68c5e8c4730ef5d2p3@PAX1
2.3e-51FFCP PHASE2:Hg19::chr10:81923378..81923389,-#_b69d6d8afd1a22a6f5b4567cbc99ae2ep@chr10:81923378..81923389, -
2.3e-51FFCP PHASE1:Hg19::chr10:81923378..81923389,-#_b69d6d8afd1a22a6f5b4567cbc99ae2ep@chr10:81923378..81923389, -
3.24e-51FFCP PHASE2:Hg19::chr2:12248310..12248334,-#_d0372fa1f7be2280b28cc8b0603e9a6dp@chr2:12248310..12248334, -
3.24e-51FFCP PHASE1:Hg19::chr2:12248310..12248334,-#_d0372fa1f7be2280b28cc8b0603e9a6dp@chr2:12248310..12248334, -
8.0e-51FFCP PHASE1:Hg19::chr7:18832913..18832946,+#_4371e688c332abd6ad5aac385b0f6dc2p19@HDAC9
8.0e-51FFCP PHASE2:Hg19::chr7:18832913..18832946,+#_4371e688c332abd6ad5aac385b0f6dc2p19@HDAC9
5.06e-49FFCP PHASE1:Hg19::chr7:158224707..158224729,-#_a0d3d55ea4e09d98fcc78fbe2ffbbb5bp@chr7:158224707..158224729, -
5.06e-49FFCP PHASE2:Hg19::chr7:158224707..158224729,-#_a0d3d55ea4e09d98fcc78fbe2ffbbb5bp@chr7:158224707..158224729, -
5.24e-48FFCP PHASE1:Hg19::chr1:65888177..65888194,+#_d70fa75fa58095d3ea0e530bc8a7bd2ap@chr1:65888177..65888194, +
5.24e-48FFCP PHASE2:Hg19::chr1:65888177..65888194,+#_d70fa75fa58095d3ea0e530bc8a7bd2ap@chr1:65888177..65888194, +
2.98e-45FFCP PHASE2:Hg19::chr4:13546583..13546593,-#_8843d8fd77d7ddca669c7e828fcf666bp3@NKX3-2
2.98e-45FFCP PHASE1:Hg19::chr4:13546583..13546593,-#_8843d8fd77d7ddca669c7e828fcf666bp3@NKX3-2
2.92e-44FFCP PHASE1:Hg19::chr1:78695274..78695292,+#_6b5064f6f9a31f7e0da49a2c5c5d5e8dp1@MGC27382
2.92e-44FFCP PHASE2:Hg19::chr1:78695274..78695292,+#_6b5064f6f9a31f7e0da49a2c5c5d5e8dp1@MGC27382
1.71e-43FFCP PHASE1:Hg19::chr7:18832834..18832859,+#_fa8e4c739a40a9360fd599f9b1ce0d45p18@HDAC9
1.71e-43FFCP PHASE2:Hg19::chr7:18832834..18832859,+#_fa8e4c739a40a9360fd599f9b1ce0d45p18@HDAC9
1.48e-40FFCP PHASE2:Hg19::chr9:33028063..33028067,-#_77d92016a3a09ba5be83a2854d85be12p@chr9:33028063..33028067, -
1.48e-40FFCP PHASE1:Hg19::chr9:33028063..33028067,-#_77d92016a3a09ba5be83a2854d85be12p@chr9:33028063..33028067, -
1.48e-40FFCP PHASE1:Hg19::chr13:24914614..24914622,-#_77d92016a3a09ba5be83a2854d85be12p@chr13:24914614..24914622, -
1.48e-40FFCP PHASE2:Hg19::chr13:24914614..24914622,-#_77d92016a3a09ba5be83a2854d85be12p@chr13:24914614..24914622, -
1.64e-40FFCP PHASE2:Hg19::chr20:21686317..21686350,+#_4846cff8daee7328f4a3f63bae0dc572p1@PAX1
1.64e-40FFCP PHASE1:Hg19::chr20:21686317..21686350,+#_4846cff8daee7328f4a3f63bae0dc572p1@PAX1
1.81e-40FFCP PHASE2:Hg19::chr1:78769549..78769554,+#_a6da34f909ffd76f093df2fe7e393e26p5@PTGFR
1.81e-40FFCP PHASE1:Hg19::chr1:78769549..78769554,+#_a6da34f909ffd76f093df2fe7e393e26p5@PTGFR
2.13e-40FFCP PHASE1:Hg19::chr2:241897363..241897398,+#_dc21ddd42e5f6800365a3902bbba7cf8p@chr2:241897363..241897398, +
2.13e-40FFCP PHASE2:Hg19::chr2:241897363..241897398,+#_dc21ddd42e5f6800365a3902bbba7cf8p@chr2:241897363..241897398, +
3.04e-39FFCP PHASE1:Hg19::chr20:21686290..21686311,+#_d273976ab0a18b9e48acfa60e6a1c9fbp2@PAX1
3.04e-39FFCP PHASE2:Hg19::chr20:21686290..21686311,+#_d273976ab0a18b9e48acfa60e6a1c9fbp2@PAX1
7.19e-39FFCP PHASE1:Hg19::chr7:18832759..18832786,+#_e73b5dc87d4306b29a99a4360534f275p16@HDAC9
7.19e-39FFCP PHASE2:Hg19::chr7:18832759..18832786,+#_e73b5dc87d4306b29a99a4360534f275p16@HDAC9
7.19e-39FFCP PHASE2:Hg19::chr5:140887761..140887777,+#_e73b5dc87d4306b29a99a4360534f275p@chr5:140887761..140887777, +
7.19e-39FFCP PHASE1:Hg19::chr5:140887761..140887777,+#_e73b5dc87d4306b29a99a4360534f275p@chr5:140887761..140887777, +
1.24e-38FFCP PHASE2:Hg19::chr4:77068930..77068959,-#_7fff913b9fa8e6dd6fe690a262f1259bp4@NUP54
1.24e-38FFCP PHASE1:Hg19::chr4:77068930..77068959,-#_7fff913b9fa8e6dd6fe690a262f1259bp4@NUP54
2.08e-38FFCP PHASE1:Hg19::chr2:241938405..241938416,+#_be59670c9932f979a1e08c80f94a1e4cp@chr2:241938405..241938416, +
2.08e-38FFCP PHASE2:Hg19::chr2:241938405..241938416,+#_be59670c9932f979a1e08c80f94a1e4cp@chr2:241938405..241938416, +
3.34e-38FFCP PHASE2:Hg19::chr4:13546632..13546662,-#_ea060c514aac601df53800f635c36ffdp1@NKX3-2
3.34e-38FFCP PHASE1:Hg19::chr4:13546632..13546662,-#_ea060c514aac601df53800f635c36ffdp1@NKX3-2
3.68e-38FFCP PHASE1:Hg19::chr6:158490457..158490470,+#_8eb7419ef8f88abffd55381947bb7f46p10@SYNJ2
3.68e-38FFCP PHASE2:Hg19::chr6:158490457..158490470,+#_8eb7419ef8f88abffd55381947bb7f46p10@SYNJ2
5.39e-38FFCP PHASE2:Hg19::chr9:16138889..16138902,-#_750f71df064425496f128ca14d8694e6p@chr9:16138889..16138902, -
5.39e-38FFCP PHASE1:Hg19::chr9:16138889..16138902,-#_750f71df064425496f128ca14d8694e6p@chr9:16138889..16138902, -
8.66e-38FFCP PHASE2:Hg19::chr8:78311303..78311320,+#_21917a3c7ac00e6af16fc0eb0738cd52p2@ENST00000518706
8.66e-38FFCP PHASE1:Hg19::chr8:78311303..78311320,+#_21917a3c7ac00e6af16fc0eb0738cd52p2@ENST00000518706
2.96e-37FFCP PHASE1:Hg19::chr21:39705383..39705394,-#_23cc93890b2ea4c605e859f1c2137bdep1@ENST00000436845
2.96e-37FFCP PHASE2:Hg19::chr21:39705383..39705394,-#_23cc93890b2ea4c605e859f1c2137bdep1@ENST00000436845
6.92e-37FFCP PHASE2:Hg19::chr9:123239747..123239765,-#_e7b738b660a00850522dc1b665fb07f4p12@CDK5RAP2
6.92e-37FFCP PHASE1:Hg19::chr9:123239747..123239765,-#_e7b738b660a00850522dc1b665fb07f4p12@CDK5RAP2
3.28e-36FFCP PHASE1:Hg19::chr1:78695298..78695311,+#_4ea36373b8f73438c2e7c74f5295cb02p1@ENST00000413519
3.28e-36FFCP PHASE2:Hg19::chr1:78695298..78695311,+#_4ea36373b8f73438c2e7c74f5295cb02p1@ENST00000413519
9.62e-35FFCP PHASE1:Hg19::chr14:37126814..37126834,+#_dafeab5abc8807bbf5ec6483dd899e96p4@PAX9
9.62e-35FFCP PHASE2:Hg19::chr14:37126814..37126834,+#_dafeab5abc8807bbf5ec6483dd899e96p4@PAX9
1.8e-34FFCP PHASE1:Hg19::chr7:100202784..100202796,-#_c920ee3abfd2fd38eaf8bc175da8252cp@chr7:100202784..100202796, -
1.8e-34FFCP PHASE2:Hg19::chr7:100202784..100202796,-#_c920ee3abfd2fd38eaf8bc175da8252cp@chr7:100202784..100202796, -
3.69e-34FFCP PHASE1:Hg19::chr12:54422268..54422278,+#_84ffe853fe6702b5e7f125f1c6347ef8p8@HOXC6
3.69e-34FFCP PHASE2:Hg19::chr12:54422268..54422278,+#_84ffe853fe6702b5e7f125f1c6347ef8p8@HOXC6
5.52e-34FFCP PHASE2:Hg19::chr11:60610073..60610090,+#_adfad40cac0239c327ec8bbfc3411644p6@CCDC86
5.52e-34FFCP PHASE1:Hg19::chr11:60610073..60610090,+#_adfad40cac0239c327ec8bbfc3411644p6@CCDC86
1.43e-33FFCP PHASE2:Hg19::chr20:21695435..21695452,+#_4e10f1d03253c3e169c756f15543124ep@chr20:21695435..21695452, +
1.43e-33FFCP PHASE1:Hg19::chr20:21695435..21695452,+#_4e10f1d03253c3e169c756f15543124ep@chr20:21695435..21695452, +
5.36e-33FFCP PHASE1:Hg19::chr16:70795228..70795237,+#_cf6f55555cddcd168e3cc38397971564p@chr16:70795228..70795237, +
5.36e-33FFCP PHASE2:Hg19::chr16:70795228..70795237,+#_cf6f55555cddcd168e3cc38397971564p@chr16:70795228..70795237, +
1.05e-32FFCP PHASE1:Hg19::chr3:158384350..158384362,-#_c67c79b30ede90951c77c32b9b1416acp@chr3:158384350..158384362, -
1.05e-32FFCP PHASE2:Hg19::chr3:158384350..158384362,-#_c67c79b30ede90951c77c32b9b1416acp@chr3:158384350..158384362, -
1.7e-32FFCP PHASE2:Hg19::chr2:158345440..158345449,-#_ad96ef3ce12a02e6b2f082e1483a3b19p9@CYTIP
1.7e-32FFCP PHASE1:Hg19::chr2:158345440..158345449,-#_ad96ef3ce12a02e6b2f082e1483a3b19p9@CYTIP
2.34e-32FFCP PHASE1:Hg19::chr18:12012068..12012098,+#_8c3557615bed4f1744e8b83dcd2c0660p@chr18:12012068..12012098, +
2.34e-32FFCP PHASE2:Hg19::chr18:12012068..12012098,+#_8c3557615bed4f1744e8b83dcd2c0660p@chr18:12012068..12012098, +
2.79e-31FFCP PHASE1:Hg19::chr14:37126870..37126882,+#_d3b4676ad757f657b9c537cfbf1c6d44p1@ENST00000555639
2.79e-31FFCP PHASE2:Hg19::chr14:37126870..37126882,+#_d3b4676ad757f657b9c537cfbf1c6d44p1@ENST00000555639

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