MCL coexpression mm9:1375
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr15:78240169..78240178,+ | p9@Mpst |
| Mm9::chr19:32669903..32669938,+ | p5@Papss2 |
| Mm9::chr3:98084350..98084367,+ | p1@Hmgcs2 |
| Mm9::chr7:133819942..133819953,- | p2@Sult1a1 |
| Mm9::chr7:90780497..90780532,+ | p1@Stard5 |
| Mm9::chr8:120225837..120225856,+ | p1@Hsd17b2 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0008202 | steroid metabolic process | 4.52099326239946e-06 |
| GO:0006694 | steroid biosynthetic process | 4.71792564992609e-05 |
| GO:0044255 | cellular lipid metabolic process | 0.000256852910400137 |
| GO:0006629 | lipid metabolic process | 0.000335389894977196 |
| GO:0008610 | lipid biosynthetic process | 0.000763104595152154 |
| GO:0016782 | transferase activity, transferring sulfur-containing groups | 0.00174788185367212 |
| GO:0016784 | 3-mercaptopyruvate sulfurtransferase activity | 0.00432022915998153 |
| GO:0004779 | sulfate adenylyltransferase activity | 0.00503957698138634 |
| GO:0017067 | tyrosine-ester sulfotransferase activity | 0.00503957698138634 |
| GO:0004781 | sulfate adenylyltransferase (ATP) activity | 0.00503957698138634 |
| GO:0004421 | hydroxymethylglutaryl-CoA synthase activity | 0.00503957698138634 |
| GO:0004020 | adenylylsulfate kinase activity | 0.00503957698138634 |
| GO:0050327 | testosterone 17-beta-dehydrogenase activity | 0.00668680369197086 |
| GO:0016740 | transferase activity | 0.00668680369197086 |
| GO:0004062 | aryl sulfotransferase activity | 0.00671759538684697 |
| GO:0006791 | sulfur utilization | 0.00671759538684697 |
| GO:0004792 | thiosulfate sulfurtransferase activity | 0.00671759538684697 |
| GO:0000103 | sulfate assimilation | 0.00671759538684697 |
| GO:0016783 | sulfurtransferase activity | 0.00755625970617706 |
| GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer | 0.00755625970617706 |
| GO:0005743 | mitochondrial inner membrane | 0.00906493270344742 |
| GO:0017127 | cholesterol transporter activity | 0.00906493270344742 |
| GO:0015248 | sterol transporter activity | 0.00906493270344742 |
| GO:0019866 | organelle inner membrane | 0.00906493270344742 |
| GO:0004303 | estradiol 17-beta-dehydrogenase activity | 0.00906493270344742 |
| GO:0015485 | cholesterol binding | 0.00906493270344742 |
| GO:0031966 | mitochondrial membrane | 0.00906493270344742 |
| GO:0005740 | mitochondrial envelope | 0.0101810170544678 |
| GO:0008272 | sulfate transport | 0.0124949266956514 |
| GO:0009058 | biosynthetic process | 0.012702024894884 |
| GO:0044429 | mitochondrial part | 0.012702024894884 |
| GO:0032934 | sterol binding | 0.0132071635044364 |
| GO:0008299 | isoprenoid biosynthetic process | 0.0155449035455494 |
| GO:0031975 | envelope | 0.0157144263002789 |
| GO:0031967 | organelle envelope | 0.0157144263002789 |
| GO:0016229 | steroid dehydrogenase activity | 0.0175926767312476 |
| GO:0006695 | cholesterol biosynthetic process | 0.0179298479355187 |
| GO:0006720 | isoprenoid metabolic process | 0.0224012732010386 |
| GO:0016126 | sterol biosynthetic process | 0.0224012732010386 |
| GO:0031090 | organelle membrane | 0.0260908927637333 |
| GO:0008146 | sulfotransferase activity | 0.0322638411090593 |
| GO:0005319 | lipid transporter activity | 0.0328471924877397 |
| GO:0005496 | steroid binding | 0.0328471924877397 |
| GO:0044237 | cellular metabolic process | 0.0397355137963694 |
| GO:0006790 | sulfur metabolic process | 0.039997660765998 |
| GO:0008203 | cholesterol metabolic process | 0.0417138401059138 |
| GO:0016125 | sterol metabolic process | 0.0452483082324079 |
| GO:0006869 | lipid transport | 0.0461587442985047 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.135108 |
| MA0004.1 | 0.536396 |
| MA0006.1 | 0.359699 |
| MA0007.1 | 1.29371 |
| MA0009.1 | 0.987341 |
| MA0014.1 | 0.0315641 |
| MA0017.1 | 0.387481 |
| MA0019.1 | 0.800946 |
| MA0024.1 | 0.942716 |
| MA0025.1 | 1.22395 |
| MA0027.1 | 2.64231 |
| MA0028.1 | 0.370592 |
| MA0029.1 | 0.920529 |
| MA0030.1 | 0.927235 |
| MA0031.1 | 0.890871 |
| MA0038.1 | 0.686534 |
| MA0040.1 | 1.00009 |
| MA0041.1 | 0.457338 |
| MA0042.1 | 1.12834 |
| MA0043.1 | 1.08567 |
| MA0046.1 | 1.02391 |
| MA0048.1 | 0.161427 |
| MA0050.1 | 0.57678 |
| MA0051.1 | 0.695779 |
| MA0052.1 | 1.00829 |
| MA0055.1 | 0.212634 |
| MA0056.1 | 0 |
| MA0057.1 | 0.457693 |
| MA0058.1 | 0.436487 |
| MA0059.1 | 0.449345 |
| MA0060.1 | 0.757042 |
| MA0061.1 | 0.307097 |
| MA0063.1 | 0 |
| MA0066.1 | 0.675169 |
| MA0067.1 | 1.33603 |
| MA0068.1 | 0.153907 |
| MA0069.1 | 1.00864 |
| MA0070.1 | 0.998765 |
| MA0071.1 | 0.575909 |
| MA0072.1 | 0.990133 |
| MA0073.1 | 0.0477423 |
| MA0074.1 | 0.638014 |
| MA0076.1 | 0.407465 |
| MA0077.1 | 0.968053 |
| MA0078.1 | 0.729877 |
| MA0081.1 | 0.473489 |
| MA0083.1 | 1.08487 |
| MA0084.1 | 1.66561 |
| MA0087.1 | 1.04109 |
| MA0088.1 | 0.358337 |
| MA0089.1 | 0 |
| MA0090.1 | 0.500693 |
| MA0091.1 | 0.55008 |
| MA0092.1 | 1.25163 |
| MA0093.1 | 0.379257 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.626021 |
| MA0101.1 | 0.458688 |
| MA0103.1 | 0.398766 |
| MA0105.1 | 0.199622 |
| MA0106.1 | 0.737893 |
| MA0107.1 | 0.392331 |
| MA0108.2 | 0.824407 |
| MA0109.1 | 0 |
| MA0111.1 | 0.515457 |
| MA0113.1 | 1.68825 |
| MA0114.1 | 0.822296 |
| MA0115.1 | 1.08851 |
| MA0116.1 | 0.359483 |
| MA0117.1 | 1.05576 |
| MA0119.1 | 1.16221 |
| MA0122.1 | 1.07591 |
| MA0124.1 | 1.28237 |
| MA0125.1 | 1.20757 |
| MA0130.1 | 0 |
| MA0131.1 | 0.796279 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.1226 |
| MA0136.1 | 0.658622 |
| MA0139.1 | 0.682297 |
| MA0140.1 | 0.625902 |
| MA0141.1 | 0.419361 |
| MA0142.1 | 0.876028 |
| MA0143.1 | 0.725672 |
| MA0144.1 | 0.307873 |
| MA0145.1 | 0.119202 |
| MA0146.1 | 0.0392287 |
| MA0147.1 | 0.320675 |
| MA0148.1 | 1.3627 |
| MA0149.1 | 0.464445 |
| MA0062.2 | 0.204999 |
| MA0035.2 | 0.630778 |
| MA0039.2 | 0.328366 |
| MA0138.2 | 0.788113 |
| MA0002.2 | 0.689262 |
| MA0137.2 | 0.416331 |
| MA0104.2 | 0.261255 |
| MA0047.2 | 0.685741 |
| MA0112.2 | 0.119197 |
| MA0065.2 | 0.763394 |
| MA0150.1 | 1.29346 |
| MA0151.1 | 0 |
| MA0152.1 | 0.685852 |
| MA0153.1 | 1.13945 |
| MA0154.1 | 0.159217 |
| MA0155.1 | 0.132921 |
| MA0156.1 | 0.406559 |
| MA0157.1 | 0.843181 |
| MA0158.1 | 0 |
| MA0159.1 | 0.331229 |
| MA0160.1 | 0.556423 |
| MA0161.1 | 0 |
| MA0162.1 | 0.176524 |
| MA0163.1 | 0.0423021 |
| MA0164.1 | 1.58466 |
| MA0080.2 | 0.393257 |
| MA0018.2 | 0.669032 |
| MA0099.2 | 0.781628 |
| MA0079.2 | 0.0121017 |
| MA0102.2 | 1.7182 |
| MA0258.1 | 0.290587 |
| MA0259.1 | 0.309517 |
| MA0442.1 | 0 |
