MCL coexpression mm9:818
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr13:93125094..93125131,+ | p2@Dhfr |
| Mm9::chr14:30823509..30823529,+ | p@chr14:30823509..30823529 + |
| Mm9::chr14:56097704..56097751,+ | p1@Dhrs4 |
| Mm9::chr14:56097761..56097778,+ | p@chr14:56097761..56097778 + |
| Mm9::chr15:10911502..10911520,+ | p2@Amacr |
| Mm9::chr19:10678843..10678857,- | p3@Dak |
| Mm9::chr1:164744073..164744084,- | p1@Fmo4 |
| Mm9::chr4:40090113..40090140,+ | p4@Aco1 |
| Mm9::chr6:85087737..85087775,- | p1@Spr |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0006720 | isoprenoid metabolic process | 0.00921864035950844 |
| GO:0008111 | alpha-methylacyl-CoA racemase activity | 0.0107482502539566 |
| GO:0006545 | glycine biosynthetic process | 0.0107482502539566 |
| GO:0004371 | glycerone kinase activity | 0.0107482502539566 |
| GO:0004146 | dihydrofolate reductase activity | 0.0107482502539566 |
| GO:0008300 | isoprenoid catabolic process | 0.0107482502539566 |
| GO:0042579 | microbody | 0.0107482502539566 |
| GO:0005777 | peroxisome | 0.0107482502539566 |
| GO:0003994 | aconitate hydratase activity | 0.0135507654932865 |
| GO:0030350 | iron-responsive element binding | 0.0135507654932865 |
| GO:0050662 | coenzyme binding | 0.0135507654932865 |
| GO:0004995 | tachykinin receptor activity | 0.0173476077320651 |
| GO:0016829 | lyase activity | 0.0182546376454438 |
| GO:0001758 | retinal dehydrogenase activity | 0.0182546376454438 |
| GO:0004090 | carbonyl reductase (NADPH) activity | 0.0182546376454438 |
| GO:0048037 | cofactor binding | 0.0182546376454438 |
| GO:0043288 | apocarotenoid metabolic process | 0.0182546376454438 |
| GO:0042574 | retinal metabolic process | 0.0182546376454438 |
| GO:0004499 | flavin-containing monooxygenase activity | 0.0182546376454438 |
| GO:0016491 | oxidoreductase activity | 0.0198160634969006 |
| GO:0009070 | serine family amino acid biosynthetic process | 0.0198160634969006 |
| GO:0006544 | glycine metabolic process | 0.0252121552214093 |
| GO:0050661 | NADP binding | 0.029694797603961 |
| GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor | 0.029694797603961 |
| GO:0016854 | racemase and epimerase activity | 0.029694797603961 |
| GO:0048265 | response to pain | 0.029694797603961 |
| GO:0016101 | diterpenoid metabolic process | 0.029694797603961 |
| GO:0001523 | retinoid metabolic process | 0.029694797603961 |
| GO:0006721 | terpenoid metabolic process | 0.0334383196327042 |
| GO:0006776 | vitamin A metabolic process | 0.0369292419083422 |
| GO:0009069 | serine family amino acid metabolic process | 0.0379653600349381 |
| GO:0051539 | 4 iron, 4 sulfur cluster binding | 0.0395410453392476 |
| GO:0006071 | glycerol metabolic process | 0.0395410453392476 |
| GO:0019751 | polyol metabolic process | 0.0395410453392476 |
| GO:0016645 | oxidoreductase activity, acting on the CH-NH group of donors | 0.0395410453392476 |
| GO:0006775 | fat-soluble vitamin metabolic process | 0.0399409936252014 |
| GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen | 0.0399409936252014 |
| GO:0006099 | tricarboxylic acid cycle | 0.0399409936252014 |
| GO:0055072 | iron ion homeostasis | 0.0399409936252014 |
| GO:0006879 | cellular iron ion homeostasis | 0.0399409936252014 |
| GO:0033555 | multicellular organismal response to stress | 0.0399409936252014 |
| GO:0046356 | acetyl-CoA catabolic process | 0.0399409936252014 |
| GO:0044248 | cellular catabolic process | 0.0399409936252014 |
| GO:0006091 | generation of precursor metabolites and energy | 0.0399409936252014 |
| GO:0009060 | aerobic respiration | 0.0399409936252014 |
| GO:0044242 | cellular lipid catabolic process | 0.0414499359845858 |
| GO:0009109 | coenzyme catabolic process | 0.0414499359845858 |
| GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | 0.0414499359845858 |
| GO:0045333 | cellular respiration | 0.0414499359845858 |
| GO:0003729 | mRNA binding | 0.0414499359845858 |
| GO:0051187 | cofactor catabolic process | 0.0433320978832634 |
| GO:0006084 | acetyl-CoA metabolic process | 0.045140128544238 |
| GO:0008652 | amino acid biosynthetic process | 0.0455835397780651 |
| GO:0016903 | oxidoreductase activity, acting on the aldehyde or oxo group of donors | 0.0471976368569752 |
| GO:0044255 | cellular lipid metabolic process | 0.0471976368569752 |
| GO:0042923 | neuropeptide binding | 0.0471976368569752 |
| GO:0008188 | neuropeptide receptor activity | 0.0471976368569752 |
| GO:0009056 | catabolic process | 0.0485941260019537 |
| GO:0051536 | iron-sulfur cluster binding | 0.0485941260019537 |
| GO:0019748 | secondary metabolic process | 0.0485941260019537 |
| GO:0051540 | metal cluster binding | 0.0485941260019537 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| epithelial cell | 8.90e-07 | 25 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.662116 |
| MA0004.1 | 0.394951 |
| MA0006.1 | 0.238555 |
| MA0007.1 | 0.38073 |
| MA0009.1 | 0.82278 |
| MA0014.1 | 0.119217 |
| MA0017.1 | 0.726051 |
| MA0019.1 | 0.642876 |
| MA0024.1 | 3.05882 |
| MA0025.1 | 1.05446 |
| MA0027.1 | 2.46647 |
| MA0028.1 | 0.24786 |
| MA0029.1 | 0.757957 |
| MA0030.1 | 0.764448 |
| MA0031.1 | 0.729293 |
| MA0038.1 | 0.534262 |
| MA0040.1 | 0.835181 |
| MA0041.1 | 0.323687 |
| MA0042.1 | 0.311486 |
| MA0043.1 | 0.918718 |
| MA0046.1 | 0.858391 |
| MA0048.1 | 0.993388 |
| MA0050.1 | 0.431976 |
| MA0051.1 | 0.542972 |
| MA0052.1 | 0.84317 |
| MA0055.1 | 0.221677 |
| MA0056.1 | 0 |
| MA0057.1 | 0.258928 |
| MA0058.1 | 0.305206 |
| MA0059.1 | 0.316585 |
| MA0060.1 | 0.169058 |
| MA0061.1 | 0.194456 |
| MA0063.1 | 0 |
| MA0066.1 | 0.523573 |
| MA0067.1 | 1.16502 |
| MA0068.1 | 0.077274 |
| MA0069.1 | 1.96621 |
| MA0070.1 | 0.833895 |
| MA0071.1 | 0.431174 |
| MA0072.1 | 0.825495 |
| MA0073.1 | 0.00108891 |
| MA0074.1 | 0.488775 |
| MA0076.1 | 0.279739 |
| MA0077.1 | 0.804033 |
| MA0078.1 | 0.575205 |
| MA0081.1 | 0.338098 |
| MA0083.1 | 0.917931 |
| MA0084.1 | 1.49188 |
| MA0087.1 | 0.87515 |
| MA0088.1 | 0.728131 |
| MA0089.1 | 0 |
| MA0090.1 | 0.362551 |
| MA0091.1 | 0.407455 |
| MA0092.1 | 0.362847 |
| MA0093.1 | 0.2553 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 1.20151 |
| MA0101.1 | 0.324888 |
| MA0103.1 | 0.272167 |
| MA0105.1 | 0.35523 |
| MA0106.1 | 0.582805 |
| MA0107.1 | 0.266586 |
| MA0108.2 | 0.665343 |
| MA0109.1 | 0 |
| MA0111.1 | 0.375908 |
| MA0113.1 | 0.555251 |
| MA0114.1 | 1.68389 |
| MA0115.1 | 0.921497 |
| MA0116.1 | 0.238371 |
| MA0117.1 | 0.88947 |
| MA0119.1 | 0.325434 |
| MA0122.1 | 0.909168 |
| MA0124.1 | 1.11203 |
| MA0125.1 | 1.03833 |
| MA0130.1 | 0 |
| MA0131.1 | 0.638414 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 0.954884 |
| MA0136.1 | 0.508047 |
| MA0139.1 | 0.867077 |
| MA0140.1 | 0.477483 |
| MA0141.1 | 0.29014 |
| MA0142.1 | 0.714976 |
| MA0143.1 | 0.571221 |
| MA0144.1 | 0.568165 |
| MA0145.1 | 0.200183 |
| MA0146.1 | 1.46813 |
| MA0147.1 | 0.205697 |
| MA0148.1 | 0.410398 |
| MA0149.1 | 0.330018 |
| MA0062.2 | 1.21132 |
| MA0035.2 | 0.482026 |
| MA0039.2 | 1.67243 |
| MA0138.2 | 1.52535 |
| MA0002.2 | 0.145685 |
| MA0137.2 | 0.287486 |
| MA0104.2 | 0.157347 |
| MA0047.2 | 0.533516 |
| MA0112.2 | 0.200175 |
| MA0065.2 | 0.200864 |
| MA0150.1 | 0.380623 |
| MA0151.1 | 0 |
| MA0152.1 | 0.53362 |
| MA0153.1 | 0.971406 |
| MA0154.1 | 0.0809407 |
| MA0155.1 | 0.845235 |
| MA0156.1 | 0.763978 |
| MA0157.1 | 0.683365 |
| MA0158.1 | 0 |
| MA0159.1 | 0.214506 |
| MA0160.1 | 0.413266 |
| MA0161.1 | 0 |
| MA0162.1 | 0.348617 |
| MA0163.1 | 0.0600297 |
| MA0164.1 | 0.508398 |
| MA0080.2 | 0.737531 |
| MA0018.2 | 0.51781 |
| MA0099.2 | 0.624421 |
| MA0079.2 | 0.33524 |
| MA0102.2 | 1.5442 |
| MA0258.1 | 0.180934 |
| MA0259.1 | 0.196451 |
| MA0442.1 | 0 |
