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|gostat_on_coexpression_clusters=GO:0050528!acyloxyacyl hydrolase activity!0.00468032497350759!313$GO:0004465!lipoprotein lipase activity!0.00842260114111378!313$GO:0031348!negative regulation of defense response!0.00842260114111378!313$GO:0019841!retinol binding!0.00842260114111378!116362$GO:0050728!negative regulation of inflammatory response!0.00842260114111378!313$GO:0016918!retinal binding!0.00883645061134167!116362$GO:0008653!lipopolysaccharide metabolic process!0.00883645061134167!313$GO:0005501!retinoid binding!0.00883645061134167!116362$GO:0019840!isoprenoid binding!0.00883645061134167!116362$GO:0050727!regulation of inflammatory response!0.0106295889560112!313$GO:0031347!regulation of defense response!0.0106295889560112!313$GO:0048583!regulation of response to stimulus!0.0136372896623196!313$GO:0044264!cellular polysaccharide metabolic process!0.0286786892116701!313$GO:0005976!polysaccharide metabolic process!0.0286786892116701!313$GO:0016298!lipase activity!0.0438139912943119!313
|gostat_on_coexpression_clusters=GO:0050528!acyloxyacyl hydrolase activity!0.00468032497350759!313$GO:0004465!lipoprotein lipase activity!0.00842260114111378!313$GO:0031348!negative regulation of defense response!0.00842260114111378!313$GO:0019841!retinol binding!0.00842260114111378!116362$GO:0050728!negative regulation of inflammatory response!0.00842260114111378!313$GO:0016918!retinal binding!0.00883645061134167!116362$GO:0008653!lipopolysaccharide metabolic process!0.00883645061134167!313$GO:0005501!retinoid binding!0.00883645061134167!116362$GO:0019840!isoprenoid binding!0.00883645061134167!116362$GO:0050727!regulation of inflammatory response!0.0106295889560112!313$GO:0031347!regulation of defense response!0.0106295889560112!313$GO:0048583!regulation of response to stimulus!0.0136372896623196!313$GO:0044264!cellular polysaccharide metabolic process!0.0286786892116701!313$GO:0005976!polysaccharide metabolic process!0.0286786892116701!313$GO:0016298!lipase activity!0.0438139912943119!313
|id=C625
|id=C625
|ontology_enrichment_celltype=CL:0000037!2.13e-44!172;CL:0000566!2.13e-44!172;CL:0000738!1.02e-41!140;CL:0002032!1.14e-41!165;CL:0000837!1.14e-41!165;CL:0000988!6.76e-40!182;CL:0002087!2.28e-36!119;CL:0002031!7.57e-35!124;CL:0000763!8.20e-35!112;CL:0000049!8.20e-35!112;CL:0000766!1.17e-34!76;CL:0002009!1.10e-30!65;CL:0000557!1.19e-30!71;CL:0002194!1.71e-30!63;CL:0000576!1.71e-30!63;CL:0000040!1.71e-30!63;CL:0000559!1.71e-30!63;CL:0000839!1.45e-29!70;CL:0002057!9.95e-29!42;CL:0000860!5.53e-26!45;CL:0002393!7.85e-08!9;CL:0002397!7.85e-08!9;CL:0000838!3.47e-07!52;CL:0000542!3.97e-07!53;CL:0000051!3.97e-07!53;CL:0000084!7.77e-07!25;CL:0000827!7.77e-07!25
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002390!3.60e-33!102;UBERON:0003061!3.60e-33!102;UBERON:0002193!2.14e-32!112;UBERON:0007023!3.24e-30!115;UBERON:0002371!1.89e-25!80;UBERON:0002405!1.84e-23!115;UBERON:0001474!5.15e-23!86;UBERON:0004765!4.70e-16!101;UBERON:0001434!4.70e-16!101;UBERON:0003081!8.40e-11!216;UBERON:0001049!3.06e-09!57;UBERON:0005068!3.06e-09!57;UBERON:0006241!3.06e-09!57;UBERON:0007135!3.06e-09!57;UBERON:0003080!1.90e-07!42;UBERON:0002780!2.68e-07!41;UBERON:0001890!2.68e-07!41;UBERON:0006240!2.68e-07!41;UBERON:0002616!7.77e-07!59;UBERON:0000178!9.76e-07!15;UBERON:0000179!9.76e-07!15;UBERON:0000463!9.76e-07!15
}}
}}

Revision as of 14:55, 21 May 2012


Full id: C625_CD14_Neutrophils_Basophils_CD14CD16_Peripheral_Eosinophils_Macrophage



Phase1 CAGE Peaks

Hg19::chr12:133065321..133065365,+p@chr12:133065321..133065365
+
Hg19::chr12:69742296..69742328,-p@chr12:69742296..69742328
-
Hg19::chr12:69747672..69747700,-p2@ENST00000548626
Hg19::chr12:69747723..69747752,-p1@ENST00000548900
Hg19::chr17:7077743..7077758,-p@chr17:7077743..7077758
-
Hg19::chr17:7077765..7077789,-p@chr17:7077765..7077789
-
Hg19::chr1:10057107..10057116,+p5@RBP7
Hg19::chr22:41418135..41418155,+p@chr22:41418135..41418155
+
Hg19::chr7:36764004..36764059,-p1@AOAH
Hg19::chr7:36764062..36764124,-p2@AOAH
Hg19::chr7:36764142..36764157,-p6@AOAH
Hg19::chrX:152086373..152086414,+p3@ZNF185
Hg19::chrX:152086415..152086444,+p5@ZNF185
Hg19::chrX:152086449..152086473,+p4@ZNF185


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0050528acyloxyacyl hydrolase activity0.00468032497350759
GO:0004465lipoprotein lipase activity0.00842260114111378
GO:0031348negative regulation of defense response0.00842260114111378
GO:0019841retinol binding0.00842260114111378
GO:0050728negative regulation of inflammatory response0.00842260114111378
GO:0016918retinal binding0.00883645061134167
GO:0008653lipopolysaccharide metabolic process0.00883645061134167
GO:0005501retinoid binding0.00883645061134167
GO:0019840isoprenoid binding0.00883645061134167
GO:0050727regulation of inflammatory response0.0106295889560112
GO:0031347regulation of defense response0.0106295889560112
GO:0048583regulation of response to stimulus0.0136372896623196
GO:0044264cellular polysaccharide metabolic process0.0286786892116701
GO:0005976polysaccharide metabolic process0.0286786892116701
GO:0016298lipase activity0.0438139912943119



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
hematopoietic stem cell2.13e-44172
angioblastic mesenchymal cell2.13e-44172
leukocyte1.02e-41140
hematopoietic oligopotent progenitor cell1.14e-41165
hematopoietic multipotent progenitor cell1.14e-41165
hematopoietic cell6.76e-40182
nongranular leukocyte2.28e-36119
hematopoietic lineage restricted progenitor cell7.57e-35124
myeloid cell8.20e-35112
common myeloid progenitor8.20e-35112
myeloid leukocyte1.17e-3476
macrophage dendritic cell progenitor1.10e-3065
granulocyte monocyte progenitor cell1.19e-3071
monopoietic cell1.71e-3063
monocyte1.71e-3063
monoblast1.71e-3063
promonocyte1.71e-3063
myeloid lineage restricted progenitor cell1.45e-2970
CD14-positive, CD16-negative classical monocyte9.95e-2942
classical monocyte5.53e-2645
intermediate monocyte7.85e-089
CD14-positive, CD16-positive monocyte7.85e-089
lymphoid lineage restricted progenitor cell3.47e-0752
lymphocyte3.97e-0753
common lymphoid progenitor3.97e-0753
T cell7.77e-0725
pro-T cell7.77e-0725
Uber Anatomy
Ontology termp-valuen
hematopoietic system3.60e-33102
blood island3.60e-33102
hemolymphoid system2.14e-32112
adult organism3.24e-30115
bone marrow1.89e-2580
immune system1.84e-23115
bone element5.15e-2386
skeletal element4.70e-16101
skeletal system4.70e-16101
lateral plate mesoderm8.40e-11216
neural tube3.06e-0957
neural rod3.06e-0957
future spinal cord3.06e-0957
neural keel3.06e-0957
anterior neural tube1.90e-0742
regional part of forebrain2.68e-0741
forebrain2.68e-0741
future forebrain2.68e-0741
regional part of brain7.77e-0759
blood9.76e-0715
haemolymphatic fluid9.76e-0715
organism substance9.76e-0715


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.