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{{Coexpression_clusters
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27111,0.259989,0.390754,0.0725176,0.279739,0.108118,0.259901,0.139723,0.0708274,0.0710478,0.196248,0.102645,0.0539258,0.0709978,0.401939,0.332746,0.271338,0.242121,0.298673,0.244395,0.106889,0.128632,0.0845989,0.159153,0.0842401,0.13698,0.0874421,0.100355,0.167854,0.142846,0.0583767,0.088258,0.117657,0.0486914,0.175784,0.262778,0.373453,0.362662,0.433518,0.184359,0.00831677,0.325785,0.257476,0.291176,0.376537,0.322827,0.229571,0.0739466,0.335984,0.0156657,0.0233701,0.265058,0.256405,0.0756763,0.302133,0.0976762,0.151361,0.279606,0.286696,0.150674,0.251128,0.246177,0.35674,0.35852,0.0571822,0.213257,0.287217,0.122782,0.410951,0.289049,0.266974,0.125746,0.112897,0.398354,0.222091,0.205977,0.0675312,0.0936726,0.0671916,0.132374,0.285122,0.0280766,0.203996,0.276721,0.321965,0.264707,0.450113|tfbs_overrepresentation_for_novel_motifs=0.590005,1.54039,0.581696,0.741427,1.32255,0.739643,0.821651,1.02453,0.392841,0.151681,0.706765,0.867962,0.905351,0.809319,1.31925,0.559384,1.05593,0.471262,0.938585,0.635753,0.581762,0.975621,0.731221,0.528529,0.632849,0.892087,0.316693,0.728867,0.537869,0.297585,0.682839,1.09415,0.433165,0.911389,0.49475,0.0842336,0.491074,0.740899,2.0411,0.371755,0.493145,0.66492,0.539378,0.53106,0.314427,0.61613,0.822818,0.694903,0.173425,1.33034,0.90714,0.83543,0.699149,1.17354,1.33024,0.812467,0.54284,0.777235,0.297448,0.776148,1.13655,0.825354,1.0193,1.02706,0.844545,0.991076,1.42026,1.79268,1.08337,1.62905,0.650393,1.03936,0.248021,1.32819,0.336329,1.54953,0.305238,1.00941,1.08,0.62601,0.362435,1.02594,0.844168,1.03184,1.27559,0.109222,0.221873,0.291738,0.934646,1.89266,1.51507,1.24792,1.11156,0.441618,0.535192,0.456994,0.934671,1.15558,0.939507,0.272395,0.465545,1.1057,1.14983,1.05974,0.979006,0.701817,1.04326,0.805616,0.632569,0.516141,0.594299,1.14697,0.575476,0.717043,1.46636,0.489254,0.393155,0.681522,0.988625,1.97727,1.31973,0.932085,0.736652,0.856196,1.57854,1.0102,0.814847,1.11673,1.36323,1.15964,1.24863,0.68598,1.37788,0.852645,1.52813,0.283547,0.676268,0.729481,1.48509,2.34913,1.94535,1.44718,1.91113,1.15194,0.980848,0.768101,0.963351,2.1895,1.58937,0.437774,0.234974,0.175846,1.24902,0.383416,0.824835,1.65997,0.917558,1.28873,0.632914,0.600782,1.44595,1.23002,1.07918,0.604379,0.997702,0.843324,0.423521,0.820225,0.0401987|tfbs_overrepresentation_jaspar=MA0003.1;0.233555,MA0004.1;0.71247,MA0006.1;0.532262,MA0007.1;1.65296,MA0009.1;1.20602,MA0014.1;0.0695829,MA0017.1;0.577281,MA0019.1;0.873355,MA0024.1;1.09684,MA0025.1;1.34373,MA0027.1;2.83281,MA0028.1;0.550763,MA0029.1;1.11704,MA0030.1;1.10506,MA0031.1;1.03735,MA0038.1;0.824639,MA0040.1;1.12314,MA0041.1;0.732902,MA0042.1;0.697662,MA0043.1;1.20635,MA0046.1;1.19471,MA0048.1;0.25531,MA0050.1;0.69864,MA0051.1;0.820063,MA0052.1;1.12718,MA0055.1;3.24355,MA0056.1;0,MA0057.1;0.248209,MA0058.1;0.605914,MA0059.1;0.604454,MA0060.1;1.01899,MA0061.1;0.360128,MA0063.1;0,MA0066.1;0.825101,MA0067.1;1.53181,MA0068.1;0.841508,MA0069.1;1.19071,MA0070.1;1.17908,MA0071.1;0.782546,MA0072.1;1.1744,MA0073.1;2.83685,MA0074.1;0.819248,MA0076.1;0.623864,MA0077.1;1.16637,MA0078.1;0.926725,MA0081.1;0.604638,MA0083.1;1.21381,MA0084.1;1.72172,MA0087.1;1.17185,MA0088.1;0.536981,MA0089.1;0,MA0090.1;0.640115,MA0091.1;0.715356,MA0092.1;0.673508,MA0093.1;0.535768,MA0095.1;0,MA0098.1;0,MA0100.1;0.83965,MA0101.1;0.539569,MA0103.1;1.29536,MA0105.1;0.232357,MA0106.1;0.869173,MA0107.1;0.453492,MA0108.2;1.03412,MA0109.1;0,MA0111.1;0.655276,MA0113.1;0.886811,MA0114.1;0.447443,MA0115.1;1.45393,MA0116.1;0.457606,MA0117.1;1.24497,MA0119.1;0.586221,MA0122.1;1.27173,MA0124.1;1.41151,MA0125.1;1.32534,MA0130.1;0,MA0131.1;0.94608,MA0132.1;0,MA0133.1;0,MA0135.1;1.23748,MA0136.1;0.832277,MA0139.1;0.344952,MA0140.1;0.779643,MA0141.1;0.602484,MA0142.1;1.00381,MA0143.1;0.887001,MA0144.1;0.430413,MA0145.1;0.569905,MA0146.1;0.8309,MA0147.1;0.46175,MA0148.1;0.739888,MA0149.1;0.769072,MA0062.2;0.353589,MA0035.2;0.778873,MA0039.2;1.5472,MA0138.2;0.928035,MA0002.2;0.379056,MA0137.2;0.558189,MA0104.2;0.392359,MA0047.2;0.856092,MA0112.2;2.35508,MA0065.2;0.577908,MA0150.1;0.633493,MA0151.1;0,MA0152.1;0.78681,MA0153.1;1.30799,MA0154.1;1.21162,MA0155.1;2.30186,MA0156.1;0.560797,MA0157.1;0.97481,MA0158.1;0,MA0159.1;0.462502,MA0160.1;0.756582,MA0161.1;0,MA0162.1;0.0928415,MA0163.1;0.0725493,MA0164.1;0.90014,MA0080.2;1.32578,MA0018.2;0.870662,MA0099.2;0.7872,MA0079.2;0.20937,MA0102.2;1.75932,MA0258.1;1.07498,MA0259.1;0.471671,MA0442.1;0}}
|full_id=C2610_smallcell_Neutrophils_Eosinophils_Whole_CD19_CD14_placenta
|id=C2610
|ontology_enrichment_celltype=CL:0000037!3.23e-69!172;CL:0000566!3.23e-69!172;CL:0002032!5.51e-64!165;CL:0000837!5.51e-64!165;CL:0000988!1.10e-62!182;CL:0000738!1.11e-57!140;CL:0002087!7.77e-50!119;CL:0002031!4.40e-47!124;CL:0000763!4.26e-40!112;CL:0000049!4.26e-40!112;CL:0002057!1.54e-32!42;CL:0000766!3.50e-30!76;CL:0000860!3.32e-29!45;CL:0002009!4.67e-27!65;CL:0002194!3.33e-26!63;CL:0000576!3.33e-26!63;CL:0000040!3.33e-26!63;CL:0000559!3.33e-26!63;CL:0000839!3.08e-25!70;CL:0000557!3.21e-25!71;CL:0000542!2.74e-20!53;CL:0000051!2.74e-20!53;CL:0000838!1.21e-19!52;CL:0000945!7.83e-16!24;CL:0000826!7.83e-16!24;CL:0000134!2.07e-13!358;CL:0002320!2.02e-12!365;CL:0000236!9.05e-12!14;CL:0000219!2.33e-09!390;CL:0000094!1.73e-08!8
|ontology_enrichment_disease=DOID:2531!8.83e-12!51;DOID:0060083!8.83e-12!51;DOID:1240!3.44e-10!39;DOID:8692!6.49e-08!31
|ontology_enrichment_uberon=UBERON:0002390!5.37e-33!102;UBERON:0003061!5.37e-33!102;UBERON:0002193!5.43e-30!112;UBERON:0002371!3.00e-22!80;UBERON:0001474!3.59e-20!86;UBERON:0002405!9.47e-17!115;UBERON:0004765!2.43e-14!101;UBERON:0001434!2.43e-14!101;UBERON:0002384!1.86e-11!375;UBERON:0000178!3.49e-09!15;UBERON:0000179!3.49e-09!15;UBERON:0000463!3.49e-09!15
}}

Latest revision as of 12:09, 17 September 2013


Full id: C2610_smallcell_Neutrophils_Eosinophils_Whole_CD19_CD14_placenta



Phase1 CAGE Peaks

Hg19::chr20:2310953..2310974,+p@chr20:2310953..2310974
+
Hg19::chr6:41159227..41159256,-p1@AJ420509
Hg19::chr6:41168804..41168831,-p3@TREML2
Hg19::chr6:41168834..41168853,-p2@TREML2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen
hematopoietic stem cell7.29e-58168
angioblastic mesenchymal cell7.29e-58168
hematopoietic oligopotent progenitor cell1.71e-55161
hematopoietic multipotent progenitor cell1.71e-55161
hematopoietic cell2.37e-53177
leukocyte2.45e-52136
nongranular leukocyte2.98e-51115
hematopoietic lineage restricted progenitor cell4.41e-45120
classical monocyte7.68e-3642
CD14-positive, CD16-negative classical monocyte7.68e-3642
myeloid cell1.23e-35108
common myeloid progenitor1.23e-35108
myeloid leukocyte2.80e-3472
monopoietic cell9.92e-3159
monocyte9.92e-3159
monoblast9.92e-3159
promonocyte9.92e-3159
defensive cell9.48e-3048
phagocyte9.48e-3048
macrophage dendritic cell progenitor2.86e-2961
myeloid lineage restricted progenitor cell3.62e-2966
granulocyte monocyte progenitor cell2.01e-2567
lymphocyte of B lineage1.81e-1924
pro-B cell1.81e-1924
nucleate cell7.77e-1955
lymphocyte4.10e-1753
common lymphoid progenitor4.10e-1753
B cell2.54e-1614
lymphoid lineage restricted progenitor cell2.61e-1652
mesenchymal cell2.44e-12354
connective tissue cell1.32e-11361
stuff accumulating cell3.28e-1187
motile cell4.31e-09386
granulocyte6.23e-098
intermediate monocyte4.51e-079
CD14-positive, CD16-positive monocyte4.51e-079
Uber Anatomy
Ontology termp-valuen
hematopoietic system6.64e-3598
blood island6.64e-3598
hemolymphoid system1.15e-32108
immune system2.94e-2293
bone marrow4.99e-2276
bone element1.98e-1982
skeletal element1.56e-1690
skeletal system1.31e-13100
blood3.85e-1315
haemolymphatic fluid3.85e-1315
organism substance3.85e-1315
connective tissue4.81e-11371
lateral plate mesoderm1.45e-09203
Disease
Ontology termp-valuen
leukemia5.74e-0939
hematologic cancer9.97e-0951
immune system cancer9.97e-0951


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.233555
MA0004.10.71247
MA0006.10.532262
MA0007.11.65296
MA0009.11.20602
MA0014.10.0695829
MA0017.10.577281
MA0019.10.873355
MA0024.11.09684
MA0025.11.34373
MA0027.12.83281
MA0028.10.550763
MA0029.11.11704
MA0030.11.10506
MA0031.11.03735
MA0038.10.824639
MA0040.11.12314
MA0041.10.732902
MA0042.10.697662
MA0043.11.20635
MA0046.11.19471
MA0048.10.25531
MA0050.10.69864
MA0051.10.820063
MA0052.11.12718
MA0055.13.24355
MA0056.10
MA0057.10.248209
MA0058.10.605914
MA0059.10.604454
MA0060.11.01899
MA0061.10.360128
MA0063.10
MA0066.10.825101
MA0067.11.53181
MA0068.10.841508
MA0069.11.19071
MA0070.11.17908
MA0071.10.782546
MA0072.11.1744
MA0073.12.83685
MA0074.10.819248
MA0076.10.623864
MA0077.11.16637
MA0078.10.926725
MA0081.10.604638
MA0083.11.21381
MA0084.11.72172
MA0087.11.17185
MA0088.10.536981
MA0089.10
MA0090.10.640115
MA0091.10.715356
MA0092.10.673508
MA0093.10.535768
MA0095.10
MA0098.10
MA0100.10.83965
MA0101.10.539569
MA0103.11.29536
MA0105.10.232357
MA0106.10.869173
MA0107.10.453492
MA0108.21.03412
MA0109.10
MA0111.10.655276
MA0113.10.886811
MA0114.10.447443
MA0115.11.45393
MA0116.10.457606
MA0117.11.24497
MA0119.10.586221
MA0122.11.27173
MA0124.11.41151
MA0125.11.32534
MA0130.10
MA0131.10.94608
MA0132.10
MA0133.10
MA0135.11.23748
MA0136.10.832277
MA0139.10.344952
MA0140.10.779643
MA0141.10.602484
MA0142.11.00381
MA0143.10.887001
MA0144.10.430413
MA0145.10.569905
MA0146.10.8309
MA0147.10.46175
MA0148.10.739888
MA0149.10.769072
MA0062.20.353589
MA0035.20.778873
MA0039.21.5472
MA0138.20.928035
MA0002.20.379056
MA0137.20.558189
MA0104.20.392359
MA0047.20.856092
MA0112.22.35508
MA0065.20.577908
MA0150.10.633493
MA0151.10
MA0152.10.78681
MA0153.11.30799
MA0154.11.21162
MA0155.12.30186
MA0156.10.560797
MA0157.10.97481
MA0158.10
MA0159.10.462502
MA0160.10.756582
MA0161.10
MA0162.10.0928415
MA0163.10.0725493
MA0164.10.90014
MA0080.21.32578
MA0018.20.870662
MA0099.20.7872
MA0079.20.20937
MA0102.21.75932
MA0258.11.07498
MA0259.10.471671
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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