FF:10765-110E9: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005633 | ||
| | |accession_numbers=CAGE;DRX007805;DRR008677;DRZ000102;DRZ001487;DRZ011452;DRZ012837 | ||
| | |ancestors_in_anatomy_facet= | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | ||
| | |ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:8692 | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0101883,FF:0100740 | |||
| | |comment= | ||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
| | |datafreeze_phase=2 | ||
| | |def= | ||
| | |expression_enrichment_score=chr9:96717629..96717644,-!p1@BARX1!2.26!180.99!BARX1;;chr2:68592406..68592424,+!p1@PLEK!2.02!102.93!PLEK;;chr19:50922187..50922204,+!p1@SPIB!2.02!102.93!SPIB;;chr10:131762504..131762555,-!p1@EBF3!1.89!76.00!EBF3;;chr1:92949331..92949377,-!p2@GFI1!1.87!72.35!GFI1;;chr16:85932760..85932775,+!p1@IRF8!1.86!70.75!IRF8;;chr7:50344289..50344323,+!p1@IKZF1!1.82!65.28!IKZF1;;chr6:135502501..135502546,+!p1@MYB!1.79!72.35!MYB;;chr20:62680984..62680999,-!p1@SOX18!1.76!73.95!SOX18;;chr11:47400078..47400106,-!p1@SPI1!1.75!54.78!SPI1;;chr19:33793430..33793447,-!p1@CEBPA!1.73!210.66!CEBPA;;chr21:34442439..34442455,+!p1@OLIG1!1.67!45.65!OLIG1;;chr6:135502408..135502459,+!p2@MYB!1.64!49.53!MYB;;chr3:18486354..18486377,-!p2@SATB1!1.56!43.36!SATB1;;chr7:50344251..50344288,+!p3@IKZF1!1.54!34.01!IKZF1;;chr19:13213662..13213686,-!p1@LYL1!1.51!46.10!LYL1;;chr7:27205136..27205164,-!p1@HOXA9!1.47!28.76!HOXA9;;chr2:100759037..100759058,-!p2@AFF3!1.47!28.30!AFF3;;chr2:100759010..100759035,-!p1@AFF3!1.46!27.84!AFF3;;chr3:157824202..157824211,-!p3@SHOX2!1.41!24.88!SHOX2;;chr7:50343634..50343717,+!p2@IKZF1!1.39!23.74!IKZF1;;chr2:60780607..60780624,-!p2@BCL11A!1.33!60.71!BCL11A;;chr3:157824001..157824078,-!p2@SHOX2!1.33!20.31!SHOX2;;chr2:145277640..145277771,-!p1@ZEB2!1.32!258.13!ZEB2;;chr2:223163706..223163730,-!p1@PAX3!1.29!18.72!PAX3;;chr12:54778471..54778528,-!p1@ZNF385A!1.29!18.72!ZNF385A;;chrX:66764343..66764362,+!p4@AR!1.28!18.03!AR;;chr11:47400062..47400077,-!p2@SPI1!1.27!17.80!SPI1;;chr7:64126535..64126559,+!p2@ZNF107!1.26!36.06!ZNF107;;chr6:135502472..135502489,+!p3@MYB!1.26!17.35!MYB;;chr11:32457075..32457095,-!p1@WT1!1.26!17.12!WT1;;chr5:88178983..88179012,-!p1@MEF2C!1.23!120.74!MEF2C;;chr9:117150254..117150271,-!p1@AKNA!1.19!39.71!AKNA;;chr19:13213954..13214021,-!p4@LYL1!1.19!14.61!LYL1;;chr11:47399996..47400014,-!p4@SPI1!1.18!14.15!SPI1;;chr1:156470515..156470542,-!p2@MEF2D!1.16!70.30!MEF2D;;chr3:71631151..71631194,-!p15@FOXP1!1.14!14.38!FOXP1;;chr7:27205106..27205134,-!p2@HOXA9!1.14!12.78!HOXA9;;chr19:13213704..13213726,-!p3@LYL1!1.13!16.43!LYL1;;chr10:131762385..131762398,-!p4@EBF3!1.13!12.55!EBF3;;chr2:68592394..68592405,+!p2@PLEK!1.13!12.55!PLEK;;chr2:185463247..185463263,+!p1@ZNF804A!1.11!21.23!ZNF804A;;chrX:66763856..66763896,+!p1@AR!1.10!16.66!AR;;chr7:137620650..137620677,-!p3@CREB3L2!1.09!11.41!CREB3L2;;chr7:137620684..137620711,-!p4@CREB3L2!1.09!11.41!CREB3L2;;chr18:72922811..72922827,+!p1@TSHZ1!1.08!55.46!TSHZ1;;chr16:68119324..68119364,+!p1@NFATC3!1.07!48.16!NFATC3;;chr15:76629123..76629151,+!p1@ISL2!1.07!11.87!ISL2;;chr19:45579725..45579743,-!p1@ZNF296!1.06!47.24!ZNF296;;chr10:94449703..94449718,+!p1@HHEX!1.04!39.03!HHEX;;chr21:36260980..36261011,-!p1@RUNX1!1.02!277.76!RUNX1;;chr13:41593425..41593480,-!p1@ELF1!1.02!60.94!ELF1;;chr18:72922743..72922761,+!p3@TSHZ1!1.02!31.50!TSHZ1;;chr1:92951607..92951661,-!p1@GFI1!1.02!9.36!GFI1;;chr2:60780753..60780800,-!p1@BCL11A!1.01!45.88!BCL11A;;chr4:87857474..87857489,+!p7@AFF1!1.01!16.20!AFF1;;chr1:156470494..156470505,-!p3@MEF2D!1.01!13.47!MEF2D;;chr2:60778035..60778060,-!p4@BCL11A!1.00!10.73!BCL11A;;chr11:32457103..32457123,-!p3@WT1!1.00!8.90!WT1;;chrX:66763815..66763854,+!p2@AR!0.99!11.64!AR;;chr14:75988771..75988826,+!p1@BATF!0.98!11.64!BATF;;chr2:200320768..200320800,-!p4@SATB2!0.96!8.22!SATB2;;chr21:36421535..36421610,-!p2@RUNX1!0.95!28.99!RUNX1;;chr6:21593973..21593988,+!p1@SOX4!0.94!289.86!SOX4;;chr11:128563948..128564003,+!p1@FLI1!0.94!96.32!FLI1;;chr8:145669791..145669834,-!p1@TONSL!0.94!23.05!TONSL;;chr8:116673894..116673913,-!p12@TRPS1!0.94!7.76!TRPS1;;chr2:100758991..100759009,-!p3@AFF3!0.94!7.76!AFF3;;chr2:185463521..185463557,+!p3@ZNF804A!0.94!7.76!ZNF804A;;chr11:47399947..47399961,-!p3@SPI1!0.93!7.53!SPI1;;chr2:200323414..200323455,-!p1@SATB2!0.92!16.20!SATB2;;chr1:221052994..221053008,+!p6@HLX!0.92!8.67!HLX;;chr10:131762410..131762436,-!p2@EBF3!0.92!7.30!EBF3;;chr5:176738887..176738934,-!p1@MXD3!0.91!49.98!MXD3;;chr12:54694758..54694805,-!p1@NFE2!0.89!8.22!NFE2;;chr7:27213893..27213954,-!p1@HOXA10!0.89!6.85!HOXA10;;chr21:34442540..34442560,+!p2@OLIG1!0.89!6.85!OLIG1;;chr1:25256756..25256774,-!p1@RUNX3!0.88!12.78!RUNX3;;chr19:22817119..22817145,+!p1@ZNF492!0.88!11.41!ZNF492;;chr16:79634624..79634642,-!p1@MAF!0.87!26.48!MAF;;chr5:88179195..88179224,-!p3@MEF2C!0.87!10.50!MEF2C;;chr7:100076723..100076737,-!p3@TSC22D4!0.87!10.50!TSC22D4;;chr3:71631248..71631268,-!p26@FOXP1!0.87!6.39!FOXP1;;chr2:25475120..25475176,-!p2@DNMT3A!0.86!8.67!DNMT3A;;chr3:157823517..157823562,-!p1@SHOX2!0.85!6.62!SHOX2;;chr12:54380036..54380091,+!p4@HOXC10!0.84!5.93!HOXC10;;chr12:54380112..54380126,+!p5@HOXC10!0.84!5.93!HOXC10;;chr10:94449675..94449694,+!p2@HHEX!0.83!16.43!HHEX;;chr15:100106670..100106697,+!p4@MEF2A!0.83!9.81!MEF2A;;chrX:131623932..131623964,-!p7@MBNL3!0.83!8.44!MBNL3;;chr1:92952473..92952489,-!p3@GFI1!0.83!5.71!GFI1;;chr19:2867298..2867317,+!p2@ZNF556!0.83!5.71!ZNF556;;chr17:42295777..42295816,-!p7@UBTF!0.82!6.85!UBTF;;chr6:21597765..21597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| ||
| | |ffid_belonging_in_development=CL:0000049,CL:0000134 | ||
| | |||
| | |||
| | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M2%2529%2520cell%2520line%253aNKM-1.CNhs11864.10765-110E9.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M2%2529%2520cell%2520line%253aNKM-1.CNhs11864.10765-110E9.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M2%2529%2520cell%2520line%253aNKM-1.CNhs11864.10765-110E9.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M2%2529%2520cell%2520line%253aNKM-1.CNhs11864.10765-110E9.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M2%2529%2520cell%2520line%253aNKM-1.CNhs11864.10765-110E9.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10765-110E9 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0101883 | |||
|is_obsolete= | |||
|library_id=CNhs11864 | |||
|library_id_phase_based=2:CNhs11864 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10765 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10765 | |||
|name=acute myeloid leukemia (FAB M2) cell line:NKM-1 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11864,LSID830,release010,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0.0892813554627994,0,0,0,-0.0710366746235867,0.0892813554627994,-0.188080776730715,0.115515518183947,0,0,0,0,0,0,0,0,0,0.964563598081671,0.226523616575823,0.0892813554627994,0,0.221316853713586,0,0,0,0,0.163301352154438,0.569658924193656,0,0,-0.0436752343160629,0,0,0,0,0,0,0,0,0,0,0,0,0.0766014875980134,0.163301352154438,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0.81141629162035,0,0,0,0.233659477240319,0,0,0.0659577249413412,0,0,0,0,0,0,0,0,0.0892813554627994,0,0.0892813554627994,0,0,0,0,0,0,0,0,0,0,0.0157193228284032,0,0,-0.163334838071297,0,0,0,0.0308345286509742,0.142937573363678,0,0,0,0,-0.0980353512377064,0.0840240037631308,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.483798325716919,0,0,0,-0.0270351810347199,-0.169812993378831,0,0,0.158892436546947,0.0446406777313997,0,0 | |||
|repeat_enrich_byname=0,0,0,0,-0.0980353512377064,0,0,0.226523616575823,0,0,0,0,0,0,0,0,-0.247178875285564,0.104738124148278,-0.384804863289209,-0.0542337870606725,0,0.163301352154438,-0.261953167668108,0,0,0,0,0,0,0,0,0,-0.128119866952565,0.0892813554627994,0.0388688038734845,0,0.0892813554627994,0,0,0.0119311958591078,0.402797721220687,0,-0.060996252861598,-0.0683442610773682,0,0,0,0,-0.180959313871525,0,-0.120879483793741,0.0805811838310209,-0.221611588102807,-0.018887916780121,-0.04680465889238,0,0,0,-0.294256086539005,0.205589039700294,0,0,0.150909676284728,-0.181349618560659,0,0,-0.391044581551635,0,-0.0749171495317966,-0.0604397418968705,0,0.292765221267932,0,0,0,0,0,0.281701056973614,0,0,0,0,0,-0.0128527890900369,0.318779416714504,0.0172284238409883,0,0,0,-0.595373292884913,0,0,-0.373286155956567,-0.0431083599090373,-0.0119113545490792,-0.00493348179086206,0,0.386029164423698,-0.0538124286818197,-0.310298717039652,0.117612440160859,-0.147401849371139,-0.189981719549847,-0.0668516436262052,0.155263519273464,-0.0978537376804,-0.0485791842354198,-0.236859288807407,-0.0103120305062796,-0.170756167931021,-0.0955830754169289,0,0,0,-0.434491948754505,0,0,-0.11547485041476,0.1198872690148,-0.557725628187798,-0.074398753274993,-0.278538689270627,0.284794844257994,-0.0395325284566706,-0.175735395922981,-0.0161608355348131,-0.4215723249037,-0.265301860140723,0,-0.054071732094866,-0.0154886510536806,0.0550780970752489,0.399433877580952,0,0.114490303052285,-0.0683442610773682,0.081650676077219,-0.469003399929283,0.0888262671970326,0,-0.00627221232639885,0.129492721247682,0,0,0.33141740628484,0,0,0.19618774125276,-0.539492143030166,0.218297759564528,0,0.0515981793946205,0,-0.0245965523159848,0,0.0379422241826912,-0.0388694094563673,0,0.0380180338866887,0,0.0125221375840054,0.288895628373281,-0.0757093408762034,0.285875146727356,0.0308345286509742,0.303518094013044,0.146674059302207,-0.295060126119158,-0.788939864790226,0,-0.0881268324752877,-0.110208527796259,-0.88354475051838,0.00892075981208729,-0.015199239001535,-0.357953243669535,0,-0.399268555987854,0,-0.0631256951226669,0.0373332156633624,0.383571366893458,-0.125854327972597,1.22094978521875,0.142165504126966,0,0.241182363614462,-0.698849582311175,0,-0.0464417883839826,-0.116015197172458,0,0.0761565332411842,-0.152316910439379,0.607285184988551,-0.138989456679195,0,-0.790080158389657,0,0,-0.287745797080938,0.362991727098877,0,0.113953778550822,-0.010735149350131,0.315045657660643,0.335182247685139,0.281701056973614,0,-0.645700337992725,0,0.0892813554627994,-0.275276225335106,-0.0881786368623698,0.15989705585339,0.732231155834639,0.087334700320867,-0.108622809454255,0,0,-0.0882464105023763,1.11715319090911,0.225400324552929,0,0,-0.00743880898375401,-0.116628112990133,0,0.0446406777313997,0,0,0,0,0,0,0,0,0,0.355410775506251,-0.128309713640624,0,0.120803534542947,0,0,0,0,0,0,0,0,-0.69762495187177,-0.00264604157303449,-0.12301741567642,0,0,0,0,0.158916461508539,0.31294790163365,0.281701056973614,0.0314386456568065,0,0.0446406777313997,0,0,0.0771603623652268,0,0,0,0.140850528486807,-0.057730457053664,-0.000489667589322493,0,0,0,0.00474665537182367,0,0,0,0,-0.142967778186647,0,0,-0.257290309324366,0,-0.185068781629008,-0.0815818795468414,0,0.089270409804241,-0.346960996592965,-0.642003520186748,0,0,-0.0980457796354494,0,0,0.169895553622516,0,0.163301352154438,0,0,0,0,0,0,0,0.654363481906304,0,0,0,0,0,0,0,0,0,0,0,-0.173297459300891,-0.00294270119571104,-0.00755331597184164,0,0,0,0,0,0,-0.0241060230789031,0.0995934090455002,0,0,0,0,0,0.0892813554627994,0.0446406777313997,0,0.339990351957107,0,0,0.0446406777313997,0,0,0.233659477240319,0,0.0892813554627994,0,0,0.231031036367895,0,0,-0.188080776730715,0,0,0,0,0,0,0.0517565950354459,0,0,0,0,0,0,0.158381970938166,-0.442147443370583,0,0.0892813554627994,0,0,0,0.0892813554627994,0,0.210051677024048,0,0,0,0,0.112639242866846,0,0,0,0.309783038711486,0,-0.0710366746235867,0,0,0,0,0,0,0.165325919241463,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.143261469703871,0,-0.0579446339310554,0,0,0,-0.232628352633041,0,0,0,0,0,0,0.050310252048692,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.067075380864435,0,0,0,0,0,0,0,0.569658924193656,0,0,0.102879674564605,0,0,0.0365280733370972,0,0,0,-0.122650921415247,-0.238579722091748,0.0622322903274392,0,0,0,0.132934359548552,0.81141629162035,0,0,0,-0.0667773874189013,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0892813554627994,0.221316853713586,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0446406777313997,0,0,0,0,0,0,0,0,0,0,0,0.0552699921873828,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0446406777313997,0,0,0,0,0.163301352154438,0.0832828838857998,0,0,0,-0.213086229657044,0,0,0,0,0,0,0.163301352154438,0,0.163301352154438,0,0,0,0,0,0,0,0,0,0,0,0.163301352154438,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.178905250374571,0,0,0,0,0,0,0,0,0,0,0,0,0,0.115079276915384,0,0.00490472323277226,0,0,0.0892813554627994,0,0,0,0,0,0,0,0,0.163301352154438,0,0,0,1.04306055974802,0.588781165983156,0,0,0,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| |||
|rna_box=110 | |||
|rna_catalog_number= | |||
|rna_concentration=0.60557 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.06 | |||
|rna_od260/280=2.17 | |||
|rna_position=E9 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=1.10E+11 | |||
|rna_weight_ug=27.25065 | |||
|sample_age=33 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=ifo50476 | |||
|sample_cell_line=NKM-1 | |||
|sample_cell_lot= | |||
|sample_cell_type=myeloid progenitor cell | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=JAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=acute myeloid leukemia (FAB M2) | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=J | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;6.18909354114845e-254!GO:0043227;membrane-bound organelle;1.55647246414413e-219!GO:0043231;intracellular membrane-bound organelle;2.84357770833016e-219!GO:0043226;organelle;5.55024273845313e-210!GO:0043229;intracellular organelle;1.38011125308337e-209!GO:0005737;cytoplasm;2.40168495799064e-160!GO:0044422;organelle part;7.18358528493689e-153!GO:0044446;intracellular organelle part;2.49350589536296e-151!GO:0044444;cytoplasmic part;1.99258522684115e-117!GO:0044237;cellular metabolic process;1.48952526137117e-116!GO:0032991;macromolecular complex;4.8756687658073e-115!GO:0044238;primary metabolic process;2.1719793769277e-112!GO:0005634;nucleus;6.61692510393867e-107!GO:0043170;macromolecule metabolic process;7.33777579414341e-104!GO:0030529;ribonucleoprotein complex;6.12374104891105e-97!GO:0044428;nuclear part;2.34257610169101e-93!GO:0003723;RNA binding;7.49789378097571e-87!GO:0043233;organelle lumen;1.58570480587514e-84!GO:0031974;membrane-enclosed lumen;1.58570480587514e-84!GO:0005739;mitochondrion;9.09029325678333e-80!GO:0043283;biopolymer metabolic process;4.81906421683572e-66!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.90142805237346e-61!GO:0006396;RNA processing;2.98365282098434e-61!GO:0006412;translation;1.37350556433102e-59!GO:0043234;protein complex;8.02611121973203e-58!GO:0005515;protein binding;2.30352533289976e-56!GO:0010467;gene expression;8.59691848453425e-56!GO:0005840;ribosome;9.99300858573827e-55!GO:0031981;nuclear lumen;6.9790021692804e-54!GO:0044429;mitochondrial part;1.28111895131643e-53!GO:0006259;DNA metabolic process;4.24693767546537e-51!GO:0019538;protein metabolic process;4.58547448002803e-51!GO:0016071;mRNA metabolic process;2.24255447895676e-48!GO:0031967;organelle envelope;5.79266031915712e-48!GO:0031975;envelope;1.39349681509674e-47!GO:0044267;cellular protein metabolic process;2.02163660002227e-47!GO:0003735;structural constituent of ribosome;2.84906769259389e-47!GO:0044260;cellular macromolecule metabolic process;3.67742027072193e-47!GO:0044249;cellular biosynthetic process;4.31207896165564e-46!GO:0009058;biosynthetic process;4.29009632640969e-45!GO:0009059;macromolecule biosynthetic process;3.71788071628421e-44!GO:0031090;organelle membrane;8.91242441041735e-44!GO:0016043;cellular component organization and biogenesis;5.6957870663876e-42!GO:0008380;RNA splicing;2.16442618539431e-41!GO:0033036;macromolecule localization;3.33280170713338e-41!GO:0006397;mRNA processing;4.7135129727897e-41!GO:0033279;ribosomal subunit;5.51883531397121e-40!GO:0015031;protein transport;7.59917370181424e-40!GO:0003676;nucleic acid binding;2.09172335630351e-39!GO:0045184;establishment of protein localization;2.57224925481874e-37!GO:0006996;organelle organization and biogenesis;3.06892902328646e-37!GO:0022613;ribonucleoprotein complex biogenesis and assembly;8.80062433549786e-37!GO:0008104;protein localization;9.71430577541167e-37!GO:0005829;cytosol;2.08331493978698e-36!GO:0046907;intracellular transport;6.04910158767272e-35!GO:0005654;nucleoplasm;1.87045895021658e-34!GO:0065003;macromolecular complex assembly;2.02081824508469e-34!GO:0043228;non-membrane-bound organelle;5.02541916454058e-34!GO:0043232;intracellular non-membrane-bound organelle;5.02541916454058e-34!GO:0005740;mitochondrial envelope;7.42244080571033e-33!GO:0019866;organelle inner membrane;2.88242596992486e-32!GO:0000166;nucleotide binding;3.43977271682528e-32!GO:0007049;cell cycle;9.42598855751346e-32!GO:0031966;mitochondrial membrane;1.24895566214103e-31!GO:0006886;intracellular protein transport;2.95042975872074e-31!GO:0005681;spliceosome;1.88699981210415e-30!GO:0022607;cellular component assembly;3.81754824593898e-30!GO:0005743;mitochondrial inner membrane;1.24814449384832e-29!GO:0005694;chromosome;1.70238838815275e-29!GO:0006974;response to DNA damage stimulus;1.98043420179559e-28!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.19792425905186e-28!GO:0051649;establishment of cellular localization;4.43186420722445e-27!GO:0016070;RNA metabolic process;1.3473532928798e-26!GO:0051641;cellular localization;1.63637186355636e-26!GO:0044445;cytosolic part;1.00755450147037e-25!GO:0044451;nucleoplasm part;1.04424317947436e-25!GO:0022402;cell cycle process;1.53844386989094e-25!GO:0031980;mitochondrial lumen;2.42219063271883e-25!GO:0005759;mitochondrial matrix;2.42219063271883e-25!GO:0006281;DNA repair;7.63777985233352e-25!GO:0044427;chromosomal part;1.04737703762419e-24!GO:0006119;oxidative phosphorylation;2.95432248020851e-24!GO:0000278;mitotic cell cycle;4.56081482481699e-24!GO:0051276;chromosome organization and biogenesis;6.01680109404402e-24!GO:0016874;ligase activity;2.83777193170554e-23!GO:0005524;ATP binding;5.37085121646738e-23!GO:0044455;mitochondrial membrane part;7.36986627170726e-23!GO:0032553;ribonucleotide binding;1.43779203840488e-22!GO:0032555;purine ribonucleotide binding;1.43779203840488e-22!GO:0032559;adenyl ribonucleotide binding;1.51169079568766e-22!GO:0017076;purine nucleotide binding;3.10611232069946e-22!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;4.17508556102243e-22!GO:0016817;hydrolase activity, acting on acid anhydrides;4.34120916037208e-22!GO:0016462;pyrophosphatase activity;4.52893654851889e-22!GO:0030554;adenyl nucleotide binding;6.00590590049881e-22!GO:0017111;nucleoside-triphosphatase activity;1.89844933749394e-21!GO:0015934;large ribosomal subunit;6.30895275614103e-21!GO:0044265;cellular macromolecule catabolic process;7.29585375150152e-21!GO:0006512;ubiquitin cycle;8.74028734864488e-21!GO:0022618;protein-RNA complex assembly;3.02768452958334e-20!GO:0015935;small ribosomal subunit;3.1419294886243e-20!GO:0005730;nucleolus;3.38483487728738e-20!GO:0006325;establishment and/or maintenance of chromatin architecture;9.48795492637715e-20!GO:0009719;response to endogenous stimulus;1.9412464934677e-19!GO:0022403;cell cycle phase;2.73103401790874e-19!GO:0006323;DNA packaging;5.35982737624861e-19!GO:0006260;DNA replication;6.15235151641688e-19!GO:0042623;ATPase activity, coupled;7.37031219418186e-19!GO:0043285;biopolymer catabolic process;7.37031219418186e-19!GO:0005746;mitochondrial respiratory chain;7.74998817280479e-19!GO:0016887;ATPase activity;1.29471725925715e-18!GO:0000087;M phase of mitotic cell cycle;3.54287009938875e-18!GO:0009057;macromolecule catabolic process;6.47946507371371e-18!GO:0007067;mitosis;8.39821402899498e-18!GO:0044248;cellular catabolic process;9.76593553598156e-18!GO:0043412;biopolymer modification;1.51778222840695e-17!GO:0006605;protein targeting;1.70115656256603e-17!GO:0042254;ribosome biogenesis and assembly;2.6291625179153e-17!GO:0051186;cofactor metabolic process;6.38755730127297e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;2.90249657220466e-16!GO:0019941;modification-dependent protein catabolic process;3.09266708036996e-16!GO:0043632;modification-dependent macromolecule catabolic process;3.09266708036996e-16!GO:0050136;NADH dehydrogenase (quinone) activity;3.14339990925336e-16!GO:0003954;NADH dehydrogenase activity;3.14339990925336e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.14339990925336e-16!GO:0006511;ubiquitin-dependent protein catabolic process;3.68225891078526e-16!GO:0051301;cell division;3.71827956725663e-16!GO:0006457;protein folding;3.72443803042381e-16!GO:0000502;proteasome complex (sensu Eukaryota);3.99822884289264e-16!GO:0031965;nuclear membrane;4.9184166163923e-16!GO:0044257;cellular protein catabolic process;5.65582412503474e-16!GO:0005635;nuclear envelope;8.28774079454301e-16!GO:0008135;translation factor activity, nucleic acid binding;1.02456165099566e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.03145774262944e-15!GO:0000279;M phase;1.41275249216781e-15!GO:0005761;mitochondrial ribosome;1.55350708013377e-15!GO:0000313;organellar ribosome;1.55350708013377e-15!GO:0048770;pigment granule;2.82608074308373e-15!GO:0042470;melanosome;2.82608074308373e-15!GO:0016604;nuclear body;2.96740333502518e-15!GO:0044453;nuclear membrane part;3.07572165373634e-15!GO:0008134;transcription factor binding;3.14497795758143e-15!GO:0012505;endomembrane system;3.98743481783904e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;4.07840382492722e-15!GO:0000375;RNA splicing, via transesterification reactions;4.07840382492722e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;4.07840382492722e-15!GO:0006913;nucleocytoplasmic transport;4.80054709884301e-15!GO:0004386;helicase activity;4.9127623706781e-15!GO:0042775;organelle ATP synthesis coupled electron transport;1.10155541098401e-14!GO:0042773;ATP synthesis coupled electron transport;1.10155541098401e-14!GO:0000785;chromatin;1.15129118953998e-14!GO:0051169;nuclear transport;1.15724858648034e-14!GO:0006464;protein modification process;1.2364630319932e-14!GO:0016568;chromatin modification;1.99063696658912e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.11449725563648e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.23354710337201e-14!GO:0030964;NADH dehydrogenase complex (quinone);2.96231767651964e-14!GO:0045271;respiratory chain complex I;2.96231767651964e-14!GO:0005747;mitochondrial respiratory chain complex I;2.96231767651964e-14!GO:0006732;coenzyme metabolic process;5.01949459321003e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.00618823636068e-13!GO:0051726;regulation of cell cycle;1.20185837360227e-13!GO:0030163;protein catabolic process;2.08972249131518e-13!GO:0000074;regulation of progression through cell cycle;2.14435746625063e-13!GO:0006399;tRNA metabolic process;2.47559700855046e-13!GO:0043687;post-translational protein modification;3.9893624380992e-13!GO:0006333;chromatin assembly or disassembly;5.42877309876353e-13!GO:0009259;ribonucleotide metabolic process;6.75342860641748e-13!GO:0050657;nucleic acid transport;6.75342860641748e-13!GO:0051236;establishment of RNA localization;6.75342860641748e-13!GO:0050658;RNA transport;6.75342860641748e-13!GO:0006446;regulation of translational initiation;6.79465586941258e-13!GO:0003743;translation initiation factor activity;6.92216145836761e-13!GO:0008026;ATP-dependent helicase activity;7.05557242176275e-13!GO:0051082;unfolded protein binding;7.3824587918384e-13!GO:0006413;translational initiation;8.06682217502785e-13!GO:0006403;RNA localization;8.61784990781602e-13!GO:0006163;purine nucleotide metabolic process;1.02322606327439e-12!GO:0005643;nuclear pore;1.62996197656448e-12!GO:0006164;purine nucleotide biosynthetic process;2.2887792609394e-12!GO:0009260;ribonucleotide biosynthetic process;4.73913245712986e-12!GO:0017038;protein import;4.89894220322421e-12!GO:0006364;rRNA processing;7.28361189647384e-12!GO:0016607;nuclear speck;9.56260093456738e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.16156808096479e-11!GO:0012501;programmed cell death;1.26706359068584e-11!GO:0016072;rRNA metabolic process;1.26706359068584e-11!GO:0016787;hydrolase activity;1.27226361112731e-11!GO:0009150;purine ribonucleotide metabolic process;1.29300063932373e-11!GO:0006915;apoptosis;1.63490526862942e-11!GO:0065002;intracellular protein transport across a membrane;1.98081942255128e-11!GO:0009152;purine ribonucleotide biosynthetic process;2.87582632445211e-11!GO:0016779;nucleotidyltransferase activity;3.23790647562885e-11!GO:0051028;mRNA transport;4.37071010349805e-11!GO:0065004;protein-DNA complex assembly;6.14514160369473e-11!GO:0046930;pore complex;6.45284154493547e-11!GO:0016879;ligase activity, forming carbon-nitrogen bonds;6.55273068063605e-11!GO:0009056;catabolic process;6.8161851811661e-11!GO:0044432;endoplasmic reticulum part;1.47189616538596e-10!GO:0016192;vesicle-mediated transport;1.97810567955837e-10!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.98124088732483e-10!GO:0016740;transferase activity;2.09828461410037e-10!GO:0009060;aerobic respiration;2.51845276138719e-10!GO:0008639;small protein conjugating enzyme activity;2.8255354067309e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;3.4396323255349e-10!GO:0008219;cell death;3.69208627453809e-10!GO:0016265;death;3.69208627453809e-10!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;5.14735970804518e-10!GO:0043566;structure-specific DNA binding;5.4008297501967e-10!GO:0005783;endoplasmic reticulum;6.30908410799632e-10!GO:0004842;ubiquitin-protein ligase activity;8.15563146691628e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;8.25438435555152e-10!GO:0004812;aminoacyl-tRNA ligase activity;8.25438435555152e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;8.25438435555152e-10!GO:0030532;small nuclear ribonucleoprotein complex;9.17480709299363e-10!GO:0019787;small conjugating protein ligase activity;1.12735645741991e-09!GO:0019829;cation-transporting ATPase activity;1.12735645741991e-09!GO:0009055;electron carrier activity;1.18773082831895e-09!GO:0051188;cofactor biosynthetic process;1.19258698823783e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.24340114927162e-09!GO:0006261;DNA-dependent DNA replication;1.36362738655188e-09!GO:0048193;Golgi vesicle transport;1.39001135547275e-09!GO:0006366;transcription from RNA polymerase II promoter;1.60371379634112e-09!GO:0045333;cellular respiration;2.45195811438034e-09!GO:0043038;amino acid activation;2.46772401931028e-09!GO:0006418;tRNA aminoacylation for protein translation;2.46772401931028e-09!GO:0043039;tRNA aminoacylation;2.46772401931028e-09!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;3.61540459515051e-09!GO:0008565;protein transporter activity;3.70892096074591e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;5.4161335776197e-09!GO:0003697;single-stranded DNA binding;5.43352227730856e-09!GO:0005819;spindle;6.09910034779902e-09!GO:0015986;ATP synthesis coupled proton transport;6.96851581828162e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;6.96851581828162e-09!GO:0009141;nucleoside triphosphate metabolic process;7.98844771110702e-09!GO:0009199;ribonucleoside triphosphate metabolic process;8.06183160139542e-09!GO:0009142;nucleoside triphosphate biosynthetic process;8.18934931982076e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;8.18934931982076e-09!GO:0006606;protein import into nucleus;9.73195182732953e-09!GO:0051170;nuclear import;1.10189021387396e-08!GO:0006461;protein complex assembly;1.11566768315203e-08!GO:0009117;nucleotide metabolic process;1.16496086557118e-08!GO:0003712;transcription cofactor activity;1.20674250650938e-08!GO:0000775;chromosome, pericentric region;1.34371333176272e-08!GO:0016881;acid-amino acid ligase activity;1.42562198389633e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.79329691027284e-08!GO:0009144;purine nucleoside triphosphate metabolic process;1.79329691027284e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.90509427316872e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.90509427316872e-08!GO:0050794;regulation of cellular process;2.05192024223537e-08!GO:0051246;regulation of protein metabolic process;2.06216416819999e-08!GO:0005789;endoplasmic reticulum membrane;2.07324419978344e-08!GO:0015630;microtubule cytoskeleton;4.29147643906711e-08!GO:0015078;hydrogen ion transmembrane transporter activity;4.59806090416097e-08!GO:0006310;DNA recombination;5.29477157320997e-08!GO:0006754;ATP biosynthetic process;5.53667275357223e-08!GO:0006753;nucleoside phosphate metabolic process;5.53667275357223e-08!GO:0031497;chromatin assembly;5.79753309950743e-08!GO:0006084;acetyl-CoA metabolic process;6.57451111514923e-08!GO:0006099;tricarboxylic acid cycle;6.65890549874073e-08!GO:0046356;acetyl-CoA catabolic process;6.65890549874073e-08!GO:0046034;ATP metabolic process;7.36051041385887e-08!GO:0006793;phosphorus metabolic process;7.93606227280193e-08!GO:0006796;phosphate metabolic process;7.93606227280193e-08!GO:0003899;DNA-directed RNA polymerase activity;8.97913885749059e-08!GO:0051329;interphase of mitotic cell cycle;9.32980238863016e-08!GO:0006752;group transfer coenzyme metabolic process;9.39816216802827e-08!GO:0016469;proton-transporting two-sector ATPase complex;9.39816216802827e-08!GO:0005839;proteasome core complex (sensu Eukaryota);9.40641382740212e-08!GO:0006334;nucleosome assembly;1.09186343922404e-07!GO:0009108;coenzyme biosynthetic process;1.51718714618203e-07!GO:0051325;interphase;1.51845750844593e-07!GO:0016310;phosphorylation;1.59175531686808e-07!GO:0032446;protein modification by small protein conjugation;1.64095853271256e-07!GO:0005813;centrosome;1.75377853184805e-07!GO:0005815;microtubule organizing center;2.17610770001424e-07!GO:0016567;protein ubiquitination;3.50254494737075e-07!GO:0045259;proton-transporting ATP synthase complex;3.97263469294029e-07!GO:0004298;threonine endopeptidase activity;4.06121705794214e-07!GO:0009109;coenzyme catabolic process;4.4918158418156e-07!GO:0007005;mitochondrion organization and biogenesis;4.69711407684425e-07!GO:0000245;spliceosome assembly;4.77433660376845e-07!GO:0006401;RNA catabolic process;6.45798030545075e-07!GO:0019222;regulation of metabolic process;7.88032197770113e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;7.88631635924604e-07!GO:0008094;DNA-dependent ATPase activity;8.00121948227427e-07!GO:0005657;replication fork;9.88943975144069e-07!GO:0005794;Golgi apparatus;9.92623275757383e-07!GO:0003724;RNA helicase activity;1.60203364098493e-06!GO:0009165;nucleotide biosynthetic process;1.6182360252753e-06!GO:0042981;regulation of apoptosis;1.65789314439433e-06!GO:0005768;endosome;2.12517029192346e-06!GO:0043067;regulation of programmed cell death;2.21355818030213e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.42039525780766e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;2.83121826672459e-06!GO:0015399;primary active transmembrane transporter activity;2.83121826672459e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;2.91883434939326e-06!GO:0000151;ubiquitin ligase complex;3.06106637584063e-06!GO:0051187;cofactor catabolic process;3.06276856221084e-06!GO:0005762;mitochondrial large ribosomal subunit;3.47281358429079e-06!GO:0000315;organellar large ribosomal subunit;3.47281358429079e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;3.78397620532498e-06!GO:0003682;chromatin binding;3.98076256491737e-06!GO:0016741;transferase activity, transferring one-carbon groups;4.47415821846922e-06!GO:0008168;methyltransferase activity;4.4746712704715e-06!GO:0000075;cell cycle checkpoint;5.13305713073838e-06!GO:0051168;nuclear export;5.31095990235973e-06!GO:0006302;double-strand break repair;5.5795845077769e-06!GO:0005793;ER-Golgi intermediate compartment;5.73161979092852e-06!GO:0004518;nuclease activity;6.39954224423457e-06!GO:0005773;vacuole;6.73584334721104e-06!GO:0000323;lytic vacuole;8.31912243203408e-06!GO:0005764;lysosome;8.31912243203408e-06!GO:0048475;coated membrane;8.54294220532404e-06!GO:0030117;membrane coat;8.54294220532404e-06!GO:0050789;regulation of biological process;8.75147384934682e-06!GO:0003713;transcription coactivator activity;1.14342137362491e-05!GO:0007051;spindle organization and biogenesis;1.22040677901255e-05!GO:0006613;cotranslational protein targeting to membrane;1.27131551775549e-05!GO:0005667;transcription factor complex;1.28017782326567e-05!GO:0003678;DNA helicase activity;1.57929546325821e-05!GO:0045786;negative regulation of progression through cell cycle;1.88936266873264e-05!GO:0051427;hormone receptor binding;1.89412901059282e-05!GO:0031323;regulation of cellular metabolic process;1.92677388806846e-05!GO:0031324;negative regulation of cellular metabolic process;1.98896336811956e-05!GO:0048523;negative regulation of cellular process;2.01791412625342e-05!GO:0003690;double-stranded DNA binding;2.08227610616137e-05!GO:0006091;generation of precursor metabolites and energy;2.61550562852512e-05!GO:0006402;mRNA catabolic process;2.80713932784201e-05!GO:0003729;mRNA binding;2.80713932784201e-05!GO:0016491;oxidoreductase activity;2.87627078818575e-05!GO:0008033;tRNA processing;3.06244027570759e-05!GO:0043623;cellular protein complex assembly;3.12025002787143e-05!GO:0043492;ATPase activity, coupled to movement of substances;3.19817573733866e-05!GO:0007088;regulation of mitosis;3.36652113699715e-05!GO:0030120;vesicle coat;3.36652113699715e-05!GO:0030662;coated vesicle membrane;3.36652113699715e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.55512715522784e-05!GO:0016363;nuclear matrix;3.80580254678948e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;3.87613219986552e-05!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;4.11659624132771e-05!GO:0035257;nuclear hormone receptor binding;4.12798231777944e-05!GO:0044452;nucleolar part;4.20723383892064e-05!GO:0005770;late endosome;4.20723383892064e-05!GO:0065009;regulation of a molecular function;4.24254366151875e-05!GO:0003684;damaged DNA binding;6.50475350577623e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;6.95269868699852e-05!GO:0006818;hydrogen transport;7.29043624492354e-05!GO:0015992;proton transport;7.49014878655473e-05!GO:0019899;enzyme binding;7.75882195555811e-05!GO:0006414;translational elongation;7.95331736109102e-05!GO:0006888;ER to Golgi vesicle-mediated transport;8.25574816447577e-05!GO:0006612;protein targeting to membrane;8.25687642574889e-05!GO:0008186;RNA-dependent ATPase activity;8.48737641159629e-05!GO:0000314;organellar small ribosomal subunit;8.74632457735417e-05!GO:0005763;mitochondrial small ribosomal subunit;8.74632457735417e-05!GO:0006950;response to stress;9.01903631616595e-05!GO:0000786;nucleosome;0.000107018333061606!GO:0043021;ribonucleoprotein binding;0.000124206233435325!GO:0015980;energy derivation by oxidation of organic compounds;0.000126488289661383!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.000126558932353269!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000127844821719922!GO:0006417;regulation of translation;0.000136330024492073!GO:0032508;DNA duplex unwinding;0.000144066171504686!GO:0032392;DNA geometric change;0.000144066171504686!GO:0007059;chromosome segregation;0.000155272460176803!GO:0006383;transcription from RNA polymerase III promoter;0.000155655158331874!GO:0043069;negative regulation of programmed cell death;0.000159829192014196!GO:0030880;RNA polymerase complex;0.000165279784085265!GO:0006916;anti-apoptosis;0.000166647062967786!GO:0046483;heterocycle metabolic process;0.000169168636943621!GO:0004527;exonuclease activity;0.000184637471678529!GO:0016853;isomerase activity;0.000184808008787708!GO:0043066;negative regulation of apoptosis;0.000199835269986997!GO:0043681;protein import into mitochondrion;0.00020542105275169!GO:0051052;regulation of DNA metabolic process;0.00020683064601763!GO:0005885;Arp2/3 protein complex;0.000207411460409077!GO:0048519;negative regulation of biological process;0.000245474578960906!GO:0007006;mitochondrial membrane organization and biogenesis;0.000258759707133125!GO:0004004;ATP-dependent RNA helicase activity;0.000263610033607007!GO:0005798;Golgi-associated vesicle;0.000267377229057824!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000276166500906452!GO:0008654;phospholipid biosynthetic process;0.000298347154181047!GO:0006352;transcription initiation;0.000310561802868198!GO:0031968;organelle outer membrane;0.000317764248286926!GO:0000776;kinetochore;0.000319660763710212!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.000319660763710212!GO:0006350;transcription;0.000321407448786688!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000327552197644265!GO:0016563;transcription activator activity;0.000341743489143145!GO:0006268;DNA unwinding during replication;0.000345176598099557!GO:0005769;early endosome;0.000355240329787364!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000355774900041946!GO:0000428;DNA-directed RNA polymerase complex;0.000355774900041946!GO:0016481;negative regulation of transcription;0.000364807864820623!GO:0016564;transcription repressor activity;0.000377979470259724!GO:0045454;cell redox homeostasis;0.000391319924618283!GO:0019752;carboxylic acid metabolic process;0.000406185371264468!GO:0006338;chromatin remodeling;0.000406185371264468!GO:0006626;protein targeting to mitochondrion;0.000410169833803194!GO:0000118;histone deacetylase complex;0.000416335818843327!GO:0019867;outer membrane;0.000429563708597245!GO:0006082;organic acid metabolic process;0.000454058802656455!GO:0009892;negative regulation of metabolic process;0.000459229364471694!GO:0016251;general RNA polymerase II transcription factor activity;0.000469187573147264!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000471813400127764!GO:0006405;RNA export from nucleus;0.000475665956768224!GO:0009124;nucleoside monophosphate biosynthetic process;0.000483988773019361!GO:0009123;nucleoside monophosphate metabolic process;0.000483988773019361!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000500084064889431!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.000593388303212553!GO:0000082;G1/S transition of mitotic cell cycle;0.000600631860230251!GO:0031326;regulation of cellular biosynthetic process;0.00060346759080501!GO:0007093;mitotic cell cycle checkpoint;0.000604915510886875!GO:0006284;base-excision repair;0.000608028609158205!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000631530384844375!GO:0010468;regulation of gene expression;0.000679805826158249!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000682417263064324!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000682417263064324!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000682417263064324!GO:0005684;U2-dependent spliceosome;0.000750770932835654!GO:0006839;mitochondrial transport;0.000797229467475265!GO:0004674;protein serine/threonine kinase activity;0.00080681305214149!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.000826768679209635!GO:0000287;magnesium ion binding;0.00093454807685984!GO:0000922;spindle pole;0.000935423154617028!GO:0031072;heat shock protein binding;0.00102636186012075!GO:0005741;mitochondrial outer membrane;0.00110883822073494!GO:0000228;nuclear chromosome;0.00115008837889761!GO:0005637;nuclear inner membrane;0.00116628105988193!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00116628105988193!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00116628105988193!GO:0009161;ribonucleoside monophosphate metabolic process;0.00121354627209817!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.00121354627209817!GO:0000049;tRNA binding;0.00123095069594439!GO:0030384;phosphoinositide metabolic process;0.00142002556041951!GO:0006650;glycerophospholipid metabolic process;0.0015083426453344!GO:0043414;biopolymer methylation;0.00155294156216117!GO:0005774;vacuolar membrane;0.00156423663153422!GO:0006520;amino acid metabolic process;0.00163106625812167!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00167858569657649!GO:0048500;signal recognition particle;0.00175689952236846!GO:0006289;nucleotide-excision repair;0.00184072895926652!GO:0008047;enzyme activator activity;0.00184248739108399!GO:0044440;endosomal part;0.00185606450914245!GO:0010008;endosome membrane;0.00185606450914245!GO:0046474;glycerophospholipid biosynthetic process;0.0019205361932827!GO:0051252;regulation of RNA metabolic process;0.00193064610284682!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00193064610284682!GO:0009112;nucleobase metabolic process;0.00194162390868566!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00204882760308927!GO:0032259;methylation;0.00216219458822406!GO:0032200;telomere organization and biogenesis;0.00224393687317808!GO:0000723;telomere maintenance;0.00224393687317808!GO:0016197;endosome transport;0.00225114419621879!GO:0051287;NAD binding;0.00236115420382993!GO:0042393;histone binding;0.0023694264326939!GO:0005876;spindle microtubule;0.0023727884015024!GO:0042802;identical protein binding;0.00242777800957555!GO:0046822;regulation of nucleocytoplasmic transport;0.00248700217542145!GO:0000792;heterochromatin;0.00256130395605127!GO:0006730;one-carbon compound metabolic process;0.00256992428693412!GO:0000059;protein import into nucleus, docking;0.00263012819361661!GO:0004003;ATP-dependent DNA helicase activity;0.0027019387048151!GO:0003677;DNA binding;0.00272471839664756!GO:0047485;protein N-terminus binding;0.00276585683272226!GO:0009451;RNA modification;0.00282124271043361!GO:0005788;endoplasmic reticulum lumen;0.00282222003965664!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.00283031393664047!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.00283031393664047!GO:0009126;purine nucleoside monophosphate metabolic process;0.00283031393664047!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.00283031393664047!GO:0009615;response to virus;0.00290648823076247!GO:0008312;7S RNA binding;0.0029456151578225!GO:0008632;apoptotic program;0.00303508780799867!GO:0050790;regulation of catalytic activity;0.00304769393919736!GO:0044431;Golgi apparatus part;0.00306569034619664!GO:0003725;double-stranded RNA binding;0.00306935608224286!GO:0003887;DNA-directed DNA polymerase activity;0.00306935608224286!GO:0046489;phosphoinositide biosynthetic process;0.00306935608224286!GO:0005048;signal sequence binding;0.00311925603543545!GO:0009889;regulation of biosynthetic process;0.00311925603543545!GO:0044437;vacuolar part;0.00335270451274355!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00341163017283693!GO:0043596;nuclear replication fork;0.00343470973936195!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00344080273007543!GO:0031124;mRNA 3'-end processing;0.0034483678720994!GO:0003711;transcription elongation regulator activity;0.0035487891561632!GO:0006611;protein export from nucleus;0.00361768549692099!GO:0044262;cellular carbohydrate metabolic process;0.00363764816962983!GO:0031982;vesicle;0.00363764816962983!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00405446474546903!GO:0007243;protein kinase cascade;0.00415867066257353!GO:0022890;inorganic cation transmembrane transporter activity;0.00421918181054558!GO:0015631;tubulin binding;0.00432617927299898!GO:0005525;GTP binding;0.0044373423138427!GO:0051539;4 iron, 4 sulfur cluster binding;0.00445025330789637!GO:0043284;biopolymer biosynthetic process;0.00471497193745539!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00478957335958242!GO:0045047;protein targeting to ER;0.00478957335958242!GO:0006270;DNA replication initiation;0.00480100839469693!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00488647805493023!GO:0003714;transcription corepressor activity;0.00492080556309815!GO:0008234;cysteine-type peptidase activity;0.00495029474796155!GO:0065007;biological regulation;0.00502826063320796!GO:0040029;regulation of gene expression, epigenetic;0.00504138462292903!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00506105549637413!GO:0050662;coenzyme binding;0.00518410135033093!GO:0030118;clathrin coat;0.00526621434073562!GO:0005874;microtubule;0.00531592809934319!GO:0000152;nuclear ubiquitin ligase complex;0.00531592809934319!GO:0031988;membrane-bound vesicle;0.00541693020779539!GO:0035258;steroid hormone receptor binding;0.0056007158275006!GO:0051920;peroxiredoxin activity;0.00560929693022663!GO:0008276;protein methyltransferase activity;0.00574415354824434!GO:0008408;3'-5' exonuclease activity;0.00576450743103587!GO:0016569;covalent chromatin modification;0.00580373604139154!GO:0006144;purine base metabolic process;0.00611250705712512!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00617171288208901!GO:0015002;heme-copper terminal oxidase activity;0.00617171288208901!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00617171288208901!GO:0004129;cytochrome-c oxidase activity;0.00617171288208901!GO:0005765;lysosomal membrane;0.00620356037552515!GO:0006595;polyamine metabolic process;0.0062688784869711!GO:0016407;acetyltransferase activity;0.00629660758186595!GO:0030176;integral to endoplasmic reticulum membrane;0.00637379283345184!GO:0007052;mitotic spindle organization and biogenesis;0.00637456307605758!GO:0048471;perinuclear region of cytoplasm;0.00639506576732528!GO:0051540;metal cluster binding;0.00647044548512603!GO:0051536;iron-sulfur cluster binding;0.00647044548512603!GO:0045045;secretory pathway;0.00647808532644343!GO:0008139;nuclear localization sequence binding;0.00654624979180661!GO:0006607;NLS-bearing substrate import into nucleus;0.0068509452881076!GO:0031410;cytoplasmic vesicle;0.00699749273472161!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00713402429803478!GO:0046966;thyroid hormone receptor binding;0.00737943131332699!GO:0016584;nucleosome positioning;0.00783226118670788!GO:0016859;cis-trans isomerase activity;0.00783226118670788!GO:0043488;regulation of mRNA stability;0.00784043078628326!GO:0043487;regulation of RNA stability;0.00784043078628326!GO:0004177;aminopeptidase activity;0.00784493149949688!GO:0006220;pyrimidine nucleotide metabolic process;0.00792026999963088!GO:0000339;RNA cap binding;0.00793326043394894!GO:0000910;cytokinesis;0.00798604509922944!GO:0003924;GTPase activity;0.00812232281179942!GO:0030867;rough endoplasmic reticulum membrane;0.00814671515793971!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00829488097275135!GO:0016272;prefoldin complex;0.00849082571705508!GO:0022415;viral reproductive process;0.00858190106349496!GO:0007017;microtubule-based process;0.00866721251353786!GO:0006891;intra-Golgi vesicle-mediated transport;0.00882598946830548!GO:0004532;exoribonuclease activity;0.00890826237897308!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00890826237897308!GO:0015036;disulfide oxidoreductase activity;0.00897465816727991!GO:0000726;non-recombinational repair;0.00910864602046482!GO:0043065;positive regulation of apoptosis;0.00926361849557784!GO:0016023;cytoplasmic membrane-bound vesicle;0.00936478877273804!GO:0030521;androgen receptor signaling pathway;0.00945032298545212!GO:0030119;AP-type membrane coat adaptor complex;0.00946919434549161!GO:0000178;exosome (RNase complex);0.00950620946404599!GO:0032981;mitochondrial respiratory chain complex I assembly;0.00964386396309755!GO:0010257;NADH dehydrogenase complex assembly;0.00964386396309755!GO:0033108;mitochondrial respiratory chain complex assembly;0.00964386396309755!GO:0016408;C-acyltransferase activity;0.00967295609958992!GO:0009303;rRNA transcription;0.00967600211433308!GO:0031123;RNA 3'-end processing;0.010367340012571!GO:0030131;clathrin adaptor complex;0.010489033548213!GO:0031570;DNA integrity checkpoint;0.0105272485824369!GO:0019783;small conjugating protein-specific protease activity;0.0105272485824369!GO:0051087;chaperone binding;0.0106163798566408!GO:0030658;transport vesicle membrane;0.0108965941947437!GO:0030663;COPI coated vesicle membrane;0.0110962749900035!GO:0030126;COPI vesicle coat;0.0110962749900035!GO:0005832;chaperonin-containing T-complex;0.0112814089856549!GO:0008017;microtubule binding;0.0113362636281098!GO:0043068;positive regulation of programmed cell death;0.01139154201797!GO:0030518;steroid hormone receptor signaling pathway;0.0113980103706411!GO:0007040;lysosome organization and biogenesis;0.0113980103706411!GO:0009081;branched chain family amino acid metabolic process;0.0115012831947592!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0118092491755495!GO:0032774;RNA biosynthetic process;0.011910045544851!GO:0000781;chromosome, telomeric region;0.0120120720618352!GO:0051098;regulation of binding;0.0120500598763213!GO:0004540;ribonuclease activity;0.0120832644399787!GO:0032940;secretion by cell;0.0123495605192978!GO:0003702;RNA polymerase II transcription factor activity;0.0123495605192978!GO:0005669;transcription factor TFIID complex;0.0125441770953936!GO:0004843;ubiquitin-specific protease activity;0.0128120041034387!GO:0048487;beta-tubulin binding;0.0129075926538501!GO:0043022;ribosome binding;0.0129553466248595!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0130492601261757!GO:0006733;oxidoreduction coenzyme metabolic process;0.0130975634040245!GO:0051789;response to protein stimulus;0.0132156073069769!GO:0006986;response to unfolded protein;0.0132156073069769!GO:0007050;cell cycle arrest;0.0132172269021234!GO:0043601;nuclear replisome;0.0132408104799392!GO:0030894;replisome;0.0132408104799392!GO:0006779;porphyrin biosynthetic process;0.013459264951884!GO:0033014;tetrapyrrole biosynthetic process;0.013459264951884!GO:0006406;mRNA export from nucleus;0.0134964755847651!GO:0006118;electron transport;0.0135714832253529!GO:0006740;NADPH regeneration;0.0135714832253529!GO:0006098;pentose-phosphate shunt;0.0135714832253529!GO:0030132;clathrin coat of coated pit;0.0137105860325373!GO:0051053;negative regulation of DNA metabolic process;0.0137273433894393!GO:0016790;thiolester hydrolase activity;0.01373213289507!GO:0006351;transcription, DNA-dependent;0.0139634083906491!GO:0030137;COPI-coated vesicle;0.0142522223758066!GO:0019843;rRNA binding;0.0143582434606121!GO:0033116;ER-Golgi intermediate compartment membrane;0.0143582434606121!GO:0031647;regulation of protein stability;0.0145391279013575!GO:0018193;peptidyl-amino acid modification;0.0145391279013575!GO:0030433;ER-associated protein catabolic process;0.0147689213279164!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0147689213279164!GO:0000725;recombinational repair;0.0149694265325277!GO:0000724;double-strand break repair via homologous recombination;0.0149694265325277!GO:0016570;histone modification;0.0151937805014786!GO:0019206;nucleoside kinase activity;0.0155461340553178!GO:0009116;nucleoside metabolic process;0.0161587572354678!GO:0005652;nuclear lamina;0.016415196371612!GO:0006917;induction of apoptosis;0.0167465457643232!GO:0043189;H4/H2A histone acetyltransferase complex;0.0172482081423448!GO:0030660;Golgi-associated vesicle membrane;0.0173327351059223!GO:0031252;leading edge;0.0173724828334631!GO:0046112;nucleobase biosynthetic process;0.0174119830289537!GO:0000123;histone acetyltransferase complex;0.0175202573418579!GO:0008022;protein C-terminus binding;0.0175325226347471!GO:0044454;nuclear chromosome part;0.0176268122466005!GO:0006376;mRNA splice site selection;0.0177793632627428!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0177793632627428!GO:0006275;regulation of DNA replication;0.0177793632627428!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0178658906334733!GO:0035267;NuA4 histone acetyltransferase complex;0.0178658906334733!GO:0048037;cofactor binding;0.0180718338629969!GO:0046983;protein dimerization activity;0.0182225202850544!GO:0050851;antigen receptor-mediated signaling pathway;0.0183292766884174!GO:0004576;oligosaccharyl transferase activity;0.0185163699586308!GO:0007033;vacuole organization and biogenesis;0.0185287580286715!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0186399352115783!GO:0003746;translation elongation factor activity;0.0193803128130333!GO:0051223;regulation of protein transport;0.0193854991662185!GO:0006378;mRNA polyadenylation;0.0193854991662185!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.0194043339776611!GO:0006497;protein amino acid lipidation;0.0196587519090169!GO:0006672;ceramide metabolic process;0.0197841313400507!GO:0051656;establishment of organelle localization;0.0197989590622665!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0204141669218298!GO:0006767;water-soluble vitamin metabolic process;0.0204575238654866!GO:0012502;induction of programmed cell death;0.0206093169523177!GO:0007021;tubulin folding;0.0207338121822627!GO:0045947;negative regulation of translational initiation;0.020948987182414!GO:0000139;Golgi membrane;0.0210577626811454!GO:0000018;regulation of DNA recombination;0.0211487853132381!GO:0006506;GPI anchor biosynthetic process;0.0213367943556598!GO:0030041;actin filament polymerization;0.0220400895816955!GO:0031577;spindle checkpoint;0.0224031724268323!GO:0048522;positive regulation of cellular process;0.0224277907214657!GO:0006007;glucose catabolic process;0.0226186448191077!GO:0004221;ubiquitin thiolesterase activity;0.0231460924254319!GO:0008250;oligosaccharyl transferase complex;0.0233673139475899!GO:0045892;negative regulation of transcription, DNA-dependent;0.0237628724293935!GO:0002757;immune response-activating signal transduction;0.0239927068998443!GO:0031902;late endosome membrane;0.0246831188704439!GO:0005092;GDP-dissociation inhibitor activity;0.0250923074185789!GO:0008538;proteasome activator activity;0.0255857548825393!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.025689664415012!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0259913465046813!GO:0005096;GTPase activator activity;0.0260207656217141!GO:0006400;tRNA modification;0.0260816102070866!GO:0042770;DNA damage response, signal transduction;0.0261680886715131!GO:0004428;inositol or phosphatidylinositol kinase activity;0.0266785908885567!GO:0032561;guanyl ribonucleotide binding;0.0268232870808539!GO:0019001;guanyl nucleotide binding;0.0268232870808539!GO:0005680;anaphase-promoting complex;0.0268232870808539!GO:0005663;DNA replication factor C complex;0.0269168493580903!GO:0004448;isocitrate dehydrogenase activity;0.0269454202394625!GO:0005996;monosaccharide metabolic process;0.0270720066934703!GO:0005869;dynactin complex;0.0271454253442581!GO:0046467;membrane lipid biosynthetic process;0.0273395459951212!GO:0000819;sister chromatid segregation;0.0276445516142849!GO:0006519;amino acid and derivative metabolic process;0.0281021157344809!GO:0032039;integrator complex;0.0282899065729657!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0284511863905265!GO:0046519;sphingoid metabolic process;0.0284511863905265!GO:0004722;protein serine/threonine phosphatase activity;0.0290357317577259!GO:0000077;DNA damage checkpoint;0.0291443443226328!GO:0006505;GPI anchor metabolic process;0.0291771752098868!GO:0016044;membrane organization and biogenesis;0.0294511540187986!GO:0006778;porphyrin metabolic process;0.0297829606670959!GO:0033013;tetrapyrrole metabolic process;0.0297829606670959!GO:0005758;mitochondrial intermembrane space;0.0298672649016353!GO:0051320;S phase;0.0301831246467995!GO:0008097;5S rRNA binding;0.0303405799318547!GO:0019318;hexose metabolic process;0.0303405799318547!GO:0046426;negative regulation of JAK-STAT cascade;0.030506408801007!GO:0033558;protein deacetylase activity;0.0306968575445045!GO:0042826;histone deacetylase binding;0.0307660358142939!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0307705633179086!GO:0000070;mitotic sister chromatid segregation;0.0307718438765618!GO:0044450;microtubule organizing center part;0.031011485988692!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0314599266140601!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.0317339378140909!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.031822010696071!GO:0008213;protein amino acid alkylation;0.0318992700151257!GO:0006479;protein amino acid methylation;0.0318992700151257!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0333014288349772!GO:0045449;regulation of transcription;0.0333746759816751!GO:0009083;branched chain family amino acid catabolic process;0.0336241216765109!GO:0045815;positive regulation of gene expression, epigenetic;0.0337020490509797!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0337431356036385!GO:0008170;N-methyltransferase activity;0.0345059711407321!GO:0004407;histone deacetylase activity;0.0346470130147797!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0349469864686617!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0349469864686617!GO:0005784;translocon complex;0.0368662259231956!GO:0002764;immune response-regulating signal transduction;0.0377698401886526!GO:0030522;intracellular receptor-mediated signaling pathway;0.0381374918244323!GO:0031371;ubiquitin conjugating enzyme complex;0.0381374918244323!GO:0046365;monosaccharide catabolic process;0.0381374918244323!GO:0008180;signalosome;0.0381374918244323!GO:0051235;maintenance of localization;0.0382395459482773!GO:0042158;lipoprotein biosynthetic process;0.0387467428729699!GO:0051640;organelle localization;0.0388974720184044!GO:0030508;thiol-disulfide exchange intermediate activity;0.0390410216392672!GO:0030911;TPR domain binding;0.0391410756562327!GO:0000790;nuclear chromatin;0.0392922852243917!GO:0007034;vacuolar transport;0.0394031052627299!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0396053490794978!GO:0019213;deacetylase activity;0.0396568538961013!GO:0019079;viral genome replication;0.0398760067310664!GO:0030134;ER to Golgi transport vesicle;0.0405946493561358!GO:0000175;3'-5'-exoribonuclease activity;0.0406888907872544!GO:0005905;coated pit;0.0407475962550008!GO:0006695;cholesterol biosynthetic process;0.0407700500474873!GO:0008143;poly(A) binding;0.0414004282580078!GO:0008637;apoptotic mitochondrial changes;0.0419667981072703!GO:0004659;prenyltransferase activity;0.0429263702667444!GO:0000209;protein polyubiquitination;0.0435509390234876!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.043641620477538!GO:0050681;androgen receptor binding;0.043641620477538!GO:0031970;organelle envelope lumen;0.0446621603107634!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0447341219506996!GO:0007242;intracellular signaling cascade;0.0450135362173546!GO:0016581;NuRD complex;0.0450686158787313!GO:0006635;fatty acid beta-oxidation;0.0451080327228508!GO:0017134;fibroblast growth factor binding;0.0455620504400773!GO:0050853;B cell receptor signaling pathway;0.0455653473158024!GO:0006596;polyamine biosynthetic process;0.0461477407730795!GO:0005850;eukaryotic translation initiation factor 2 complex;0.046176468708046!GO:0007004;telomere maintenance via telomerase;0.0463917470673069!GO:0051452;cellular pH reduction;0.0463917470673069!GO:0051453;regulation of cellular pH;0.0463917470673069!GO:0045851;pH reduction;0.0463917470673069!GO:0044438;microbody part;0.0463917470673069!GO:0044439;peroxisomal part;0.0463917470673069!GO:0008652;amino acid biosynthetic process;0.0465883245117893!GO:0051338;regulation of transferase activity;0.0466568592893351!GO:0016788;hydrolase activity, acting on ester bonds;0.0470553546222082!GO:0033157;regulation of intracellular protein transport;0.048183914698613!GO:0042306;regulation of protein import into nucleus;0.048183914698613!GO:0004519;endonuclease activity;0.0482953905921819!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0483693162488567!GO:0045039;protein import into mitochondrial inner membrane;0.0483693162488567!GO:0008156;negative regulation of DNA replication;0.0489057871067598!GO:0004239;methionyl aminopeptidase activity;0.0491105063945015!GO:0008537;proteasome activator complex;0.0496131971899215 | |||
|sample_id=10765 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=MYB:2.2417740596;PITX1..3:2.0482046284;TOPORS:1.94426275848;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.84783971164;FOXP1:1.53750124017;E2F1..5:1.3361348304;AIRE:1.27209333471;HOXA9_MEIS1:1.15589866305;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.15316318796;YY1:1.15301478208;POU1F1:1.13077549015;ELF1,2,4:1.05926096914;RUNX1..3:1.0511382386;NKX6-1,2:0.989074886919;SPIB:0.939089211339;SPI1:0.930478793421;DMAP1_NCOR{1,2}_SMARC:0.87237887064;BREu{core}:0.863701933856;ZBTB16:0.816593710842;FOXP3:0.789582567378;POU2F1..3:0.743567014652;CUX2:0.704688721733;SOX{8,9,10}:0.684502345915;FOXD3:0.673585459367;T:0.639037534917;ZNF143:0.576094836984;NANOG:0.567464095455;IKZF2:0.556017254612;NR5A1,2:0.548511558484;PPARG:0.535515375155;FOXA2:0.529887161128;ELK1,4_GABP{A,B1}:0.514950299331;FOXQ1:0.499500019624;ETS1,2:0.489008826209;NFY{A,B,C}:0.485102775128;HOX{A6,A7,B6,B7}:0.461223227235;PRRX1,2:0.446848734354;CDX1,2,4:0.424888878078;CRX:0.411631020162;HES1:0.376904062635;TEF:0.370788249276;ZNF384:0.353957338459;NKX2-3_NKX2-5:0.326213631177;NR6A1:0.307819898495;IRF1,2:0.304511133927;CREB1:0.299522654847;ARID5B:0.299512541578;POU3F1..4:0.287595830671;HOX{A4,D4}:0.282824969105;HBP1_HMGB_SSRP1_UBTF:0.273105664375;EVI1:0.236057631722;ESR1:0.235953381173;NRF1:0.235669992593;GATA6:0.190289853956;POU5F1:0.142305961138;TFDP1:0.140242241597;ALX1:0.114696654599;NKX2-2,8:0.114690415061;NKX3-1:0.111470053874;OCT4_SOX2{dimer}:0.109493461218;HAND1,2:0.0827543522744;PBX1:0.0769342683535;bHLH_family:0.0581579048038;BPTF:0.0506765705882;ATF5_CREB3:0.0455943270617;IRF7:0.044166703519;VSX1,2:0.0289780251092;EN1,2:0.0123398994847;SOX17:0.00198609728427;AR:0.000246504072033;RFX2..5_RFXANK_RFXAP:-0.0135644929733;PAX2:-0.0403644157551;ZNF238:-0.056535805182;DBP:-0.0737995930664;SREBF1,2:-0.07472449316;MYOD1:-0.0796717149466;HNF4A_NR2F1,2:-0.0939320640969;GFI1:-0.0970076722816;GCM1,2:-0.105472784231;NKX2-1,4:-0.139892071209;POU6F1:-0.139972599203;FOXM1:-0.146155049752;FOXO1,3,4:-0.150302078331;GATA4:-0.157759922703;PAX4:-0.160175193244;KLF4:-0.16857921636;SMAD1..7,9:-0.171976107727;ONECUT1,2:-0.182332158247;MEF2{A,B,C,D}:-0.186454379739;MYBL2:-0.193473128871;RORA:-0.204070615976;PAX3,7:-0.205117336694;FOXL1:-0.206852042041;NFKB1_REL_RELA:-0.211811525671;ZEB1:-0.213848634386;STAT1,3:-0.215101262261;NANOG{mouse}:-0.243177030832;HNF1A:-0.2502212659;TGIF1:-0.263979310428;RXR{A,B,G}:-0.277799010276;LHX3,4:-0.28951523044;FOX{F1,F2,J1}:-0.335558735245;REST:-0.346791475263;NFIL3:-0.349849877224;CEBPA,B_DDIT3:-0.361535213161;TLX2:-0.384529785141;PAX5:-0.399512757963;SOX5:-0.411025010979;MTF1:-0.474557873959;HMGA1,2:-0.485747244887;SOX2:-0.492215855407;NFE2:-0.501023464093;CDC5L:-0.506405375702;MYFfamily:-0.51438006906;UFEwm:-0.520993440177;FOX{I1,J2}:-0.521123189365;GTF2A1,2:-0.531844428419;RXRA_VDR{dimer}:-0.55527017473;FOS_FOS{B,L1}_JUN{B,D}:-0.558711800921;ZFP161:-0.60598911753;LMO2:-0.606383368515;FOSL2:-0.623067451716;STAT5{A,B}:-0.628978211166;NKX3-2:-0.633363901459;GZF1:-0.637025844548;PRDM1:-0.639179933985;HOX{A5,B5}:-0.644650766823;EP300:-0.647562489629;ATF4:-0.652612232152;MZF1:-0.652791638443;RBPJ:-0.663214481343;PDX1:-0.670844620464;FOXN1:-0.689247826836;NHLH1,2:-0.692986341551;ZNF148:-0.704258253981;EBF1:-0.709930385507;SNAI1..3:-0.710752078928;PAX6:-0.728790281891;AHR_ARNT_ARNT2:-0.731890318261;BACH2:-0.74845416868;NR1H4:-0.758588741277;TFAP4:-0.766342201586;HLF:-0.793962869948;SRF:-0.795777234914;ADNP_IRX_SIX_ZHX:-0.801935775433;TFAP2{A,C}:-0.828443918728;TP53:-0.834483556431;ALX4:-0.85823276519;XBP1:-0.885932335109;PAX8:-0.922564730057;GTF2I:-0.941764209131;ESRRA:-0.946882257694;HIF1A:-0.957315354699;TBP:-0.96228843207;LEF1_TCF7_TCF7L1,2:-0.963132251382;TFAP2B:-0.969100386109;EGR1..3:-0.981143399058;FOX{D1,D2}:-0.990490175856;HSF1,2:-1.00017136119;XCPE1{core}:-1.01202720273;MTE{core}:-1.01502471102;ZNF423:-1.02552432446;ZIC1..3:-1.03020359355;IKZF1:-1.03689982234;RREB1:-1.03961156169;MED-1{core}:-1.04514953506;HIC1:-1.04770307879;TAL1_TCF{3,4,12}:-1.04774246895;PATZ1:-1.07931053642;STAT2,4,6:-1.11009797505;MAZ:-1.11041900189;NFE2L2:-1.11338495984;ZBTB6:-1.16662216664;RFX1:-1.17177779631;ATF2:-1.18706183498;TLX1..3_NFIC{dimer}:-1.19439912796;TEAD1:-1.32204660731;NFIX:-1.3279331707;GLI1..3:-1.37568968569;MAFB:-1.42552408386;SP1:-1.44407185355;HMX1:-1.45582196207;GFI1B:-1.49467948135;TFCP2:-1.54638463661;NFE2L1:-1.59807684361;PAX1,9:-1.64178329185;SPZ1:-1.67580829611;ATF6:-1.69403577052;TBX4,5:-1.9519782545;NFATC1..3:-1.96773408795;NR3C1:-2.00324738844;JUN:-2.25133369619 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10765-110E9;search_select_hide=table117:FF:10765-110E9 | |||
}} | }} |
Latest revision as of 15:03, 3 June 2020
Name: | acute myeloid leukemia (FAB M2) cell line:NKM-1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11864 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11864
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11864
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0304 |
10 | 10 | 0.0141 |
100 | 100 | 0.178 |
101 | 101 | 0.0622 |
102 | 102 | 0.738 |
103 | 103 | 0.689 |
104 | 104 | 0.876 |
105 | 105 | 0.93 |
106 | 106 | 0.627 |
107 | 107 | 0.903 |
108 | 108 | 0.738 |
109 | 109 | 0.141 |
11 | 11 | 0.0423 |
110 | 110 | 0.127 |
111 | 111 | 0.273 |
112 | 112 | 0.589 |
113 | 113 | 0.522 |
114 | 114 | 0.261 |
115 | 115 | 0.34 |
116 | 116 | 0.216 |
117 | 117 | 0.00442 |
118 | 118 | 0.186 |
119 | 119 | 0.173 |
12 | 12 | 0.78 |
120 | 120 | 0.203 |
121 | 121 | 0.936 |
122 | 122 | 0.907 |
123 | 123 | 2.72946e-5 |
124 | 124 | 0.108 |
125 | 125 | 0.362 |
126 | 126 | 0.631 |
127 | 127 | 0.343 |
128 | 128 | 0.671 |
129 | 129 | 0.296 |
13 | 13 | 0.0254 |
130 | 130 | 0.938 |
131 | 131 | 0.533 |
132 | 132 | 0.967 |
133 | 133 | 0.94 |
134 | 134 | 0.541 |
135 | 135 | 0.343 |
136 | 136 | 0.358 |
137 | 137 | 0.894 |
138 | 138 | 0.551 |
139 | 139 | 0.239 |
14 | 14 | 0.526 |
140 | 140 | 0.38 |
141 | 141 | 0.478 |
142 | 142 | 0.307 |
143 | 143 | 0.235 |
144 | 144 | 0.947 |
145 | 145 | 0.297 |
146 | 146 | 0.98 |
147 | 147 | 0.406 |
148 | 148 | 0.0376 |
149 | 149 | 0.832 |
15 | 15 | 0.196 |
150 | 150 | 0.583 |
151 | 151 | 0.411 |
152 | 152 | 0.27 |
153 | 153 | 0.961 |
154 | 154 | 0.666 |
155 | 155 | 0.111 |
156 | 156 | 0.437 |
157 | 157 | 0.397 |
158 | 158 | 0.96 |
159 | 159 | 0.521 |
16 | 16 | 0.956 |
160 | 160 | 0.285 |
161 | 161 | 0.12 |
162 | 162 | 0.436 |
163 | 163 | 0.221 |
164 | 164 | 0.327 |
165 | 165 | 0.569 |
166 | 166 | 0.746 |
167 | 167 | 0.179 |
168 | 168 | 0.441 |
169 | 169 | 0.102 |
17 | 17 | 0.705 |
18 | 18 | 0.751 |
19 | 19 | 0.574 |
2 | 2 | 0.545 |
20 | 20 | 0.523 |
21 | 21 | 0.0882 |
22 | 22 | 0.69 |
23 | 23 | 0.133 |
24 | 24 | 0.597 |
25 | 25 | 0.223 |
26 | 26 | 0.0176 |
27 | 27 | 0.453 |
28 | 28 | 0.842 |
29 | 29 | 0.0515 |
3 | 3 | 0.0824 |
30 | 30 | 0.136 |
31 | 31 | 0.84 |
32 | 32 | 0.399 |
33 | 33 | 0.647 |
34 | 34 | 0.776 |
35 | 35 | 0.127 |
36 | 36 | 0.0376 |
37 | 37 | 0.18 |
38 | 38 | 0.488 |
39 | 39 | 0.603 |
4 | 4 | 0.053 |
40 | 40 | 0.466 |
41 | 41 | 0.988 |
42 | 42 | 0.142 |
43 | 43 | 0.369 |
44 | 44 | 0.392 |
45 | 45 | 0.345 |
46 | 46 | 0.0572 |
47 | 47 | 0.0263 |
48 | 48 | 0.041 |
49 | 49 | 0.0533 |
5 | 5 | 0.988 |
50 | 50 | 0.916 |
51 | 51 | 0.739 |
52 | 52 | 0.617 |
53 | 53 | 0.0815 |
54 | 54 | 0.988 |
55 | 55 | 0.916 |
56 | 56 | 0.659 |
57 | 57 | 0.101 |
58 | 58 | 0.254 |
59 | 59 | 0.645 |
6 | 6 | 0.299 |
60 | 60 | 0.713 |
61 | 61 | 0.0966 |
62 | 62 | 0.208 |
63 | 63 | 0.318 |
64 | 64 | 0.201 |
65 | 65 | 0.988 |
66 | 66 | 0.167 |
67 | 67 | 0.82 |
68 | 68 | 0.844 |
69 | 69 | 0.155 |
7 | 7 | 0.114 |
70 | 70 | 0.288 |
71 | 71 | 0.0866 |
72 | 72 | 0.827 |
73 | 73 | 0.474 |
74 | 74 | 0.98 |
75 | 75 | 0.0182 |
76 | 76 | 0.0898 |
77 | 77 | 0.827 |
78 | 78 | 0.031 |
79 | 79 | 0.553 |
8 | 8 | 0.0731 |
80 | 80 | 0.361 |
81 | 81 | 0.208 |
82 | 82 | 0.4 |
83 | 83 | 0.86 |
84 | 84 | 0.621 |
85 | 85 | 0.528 |
86 | 86 | 0.117 |
87 | 87 | 0.0961 |
88 | 88 | 0.468 |
89 | 89 | 0.191 |
9 | 9 | 0.862 |
90 | 90 | 0.181 |
91 | 91 | 0.651 |
92 | 92 | 0.655 |
93 | 93 | 0.576 |
94 | 94 | 0.498 |
95 | 95 | 0.0795 |
96 | 96 | 0.604 |
97 | 97 | 0.357 |
98 | 98 | 0.299 |
99 | 99 | 0.675 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11864
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101883 acute myeloid leukemia cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0101883 (acute myeloid leukemia cell line sample)
0100740 (myeloid leukemia cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)