FF:10815-111B5: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005891 | ||
| | |accession_numbers=CAGE;DRX007882;DRR008754;DRZ000179;DRZ001564;DRZ011529;DRZ012914 | ||
| | |ancestors_in_anatomy_facet= | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0000255 | ||
| | |ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:305 | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100297,FF:0101120,FF:0011472 | |||
|comment= | |||
|created_by= | |||
| | |creation_date= | ||
| | |data_phase=2 | ||
| | |datafreeze_phase=2 | ||
| | |def= | ||
| | |expression_enrichment_score=chr6:10415484..10415508,-!p3@TFAP2A!1.73!52.73!TFAP2A;;chr6:10412600..10412637,-!p1@TFAP2A!1.53!54.38!TFAP2A;;chr6:10415276..10415341,-!p2@TFAP2A!1.49!36.19!TFAP2A;;chr17:8027418..8027432,-!p1@HES7!1.48!29.22!HES7;;chr5:134369905..134369972,-!p1@PITX1!1.42!38.80!PITX1;;chr12:85673868..85673881,+!p2@ALX1!1.40!24.09!ALX1;;chr13:73633131..73633149,+!p1@KLF5!1.35!221.18!KLF5;;chr17:26697276..26697303,-!p2@SEBOX,p2@VTN!1.34!20.71!SEBOX;;chr5:134369879..134369898,-!p2@PITX1!1.29!18.58!PITX1;;chr18:55102598..55102623,+!p1@ONECUT2!1.29!18.29!ONECUT2;;chr18:55102628..55102646,+!p2@ONECUT2!1.29!18.29!ONECUT2;;chr3:128207349..128207386,-!p3@GATA2!1.28!18.19!GATA2;;chr2:45236540..45236577,-!p1@SIX2!1.28!18.00!SIX2;;chr10:35484053..35484076,+!p1@CREM!1.23!39.57!CREM;;chr1:201979743..201979762,+!p1@ELF3!1.23!16.16!ELF3;;chr6:1312325..1312340,+!p1@FOXQ1!1.20!24.19!FOXQ1;;chr3:12330560..12330579,+!p1@PPARG!1.20!17.03!PPARG;;chr12:85673977..85674015,+!p1@ALX1!1.19!14.51!ALX1;;chr3:128206762..128206781,-!p2@GATA2!1.18!86.40!GATA2;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.17!13.74!ZBED1;;chrX:131624056..131624069,-!p2@MBNL3!1.15!18.00!MBNL3;;chr6:1389789..1389821,+!p1@FOXF2!1.15!18.00!FOXF2;;chr1:201979703..201979721,+!p2@ELF3!1.15!13.26!ELF3;;chr15:96875657..96875760,+!p14@NR2F2!1.10!19.25!NR2F2;;chr20:55204351..55204377,+!p1@TFAP2C!1.09!14.61!TFAP2C;;chr5:170736243..170736279,+!p1@TLX3!1.09!11.42!TLX3;;chr12:54378923..54378966,+!p1@HOXC10!1.08!11.03!HOXC10;;chr8:128748308..128748324,+!p2@MYC!1.07!297.14!MYC;;chr3:114790132..114790174,-!p18@ZBTB20!1.07!10.74!ZBTB20;;chr17:26697304..26697335,-!p1@SEBOX,p1@VTN!1.07!10.64!SEBOX;;chr6:126240380..126240430,+!p2@NCOA7!1.06!27.67!NCOA7;;chr6:10412392..10412409,-!p4@TFAP2A!1.06!11.90!TFAP2A;;chr3:169381420..169381535,-!p1@MECOM!1.05!12.00!MECOM;;chr12:54380404..54380433,+!p3@HOXC10!1.04!9.97!HOXC10;;chr17:46682321..46682362,-!p1@HOXB6!1.01!9.19!HOXB6;;chr12:54366894..54366922,+!p2@HOXC11!0.98!8.61!HOXC11;;chr7:73038839..73038862,-!p1@MLXIPL!0.96!8.22!MLXIPL;;chr12:2986275..2986363,-!p1@FOXM1!0.95!82.15!FOXM1;;chr17:46687959..46688007,-!p2@HOXB7!0.94!10.74!HOXB7;;chr6:1389989..1390019,+!p2@FOXF2!0.93!7.45!FOXF2;;chr11:31832658..31832681,-!p1@PAX6!0.93!7.45!PAX6;;chr12:85674018..85674039,+!p3@ALX1!0.93!7.45!ALX1;;chr17:46688334..46688385,-!p1@HOXB7!0.92!10.84!HOXB7;;chrX:131623044..131623089,-!p1@MBNL3!0.91!30.96!MBNL3;;chr9:126774018..126774055,+!p1@LHX2!0.90!6.97!LHX2;;chr3:69915385..69915438,+!p3@MITF!0.90!6.97!MITF;;chr6:20402102..20402152,+!p1@E2F3!0.89!28.93!E2F3;;chr12:54332608..54332636,+!p1@HOXC13!0.89!6.68!HOXC13;;chr6:126240442..126240459,+!p4@NCOA7!0.87!8.32!NCOA7;;chr6:10412576..10412599,-!p5@TFAP2A!0.87!6.48!TFAP2A;;chr8:10588010..10588030,-!p1@SOX7!0.87!6.39!SOX7;;chr17:41277372..41277418,-!p1@BRCA1!0.86!24.00!BRCA1;;chr1:23857698..23857733,-!p1@E2F2!0.85!11.51!E2F2;;chr12:54379136..54379150,+!p4@HOXC5!0.85!6.10!HOXC5;;chr1:151804244..151804310,-!p1@RORC!0.84!5.90!RORC;;chr20:42295745..42295765,+!p1@MYBL2!0.83!100.34!MYBL2;;chr8:128747661..128747703,+!p6@MYC!0.83!8.03!MYC;;chr1:23857325..23857416,-!p2@E2F2!0.83!6.87!E2F2;;chr7:27196267..27196311,-!p1@HOXA7!0.83!5.71!HOXA7;;chr12:54393880..54393962,+!p1@HOXC9!0.83!5.71!HOXC9;;chr12:115121962..115121987,-!p1@TBX3!0.82!50.12!TBX3;;chr5:92918919..92918942,+!p1@NR2F1!0.82!27.09!NR2F1;;chr20:42295713..42295738,+!p2@MYBL2!0.81!34.83!MYBL2;;chr2:46524897..46524911,+!p2@EPAS1!0.81!16.06!EPAS1;;chr15:66994663..66994680,+!p1@SMAD6!0.81!13.55!SMAD6;;chr3:32023232..32023273,+!p1@ZNF860!0.81!7.93!ZNF860;;chr8:55370487..55370503,+!p1@SOX17!0.81!5.42!SOX17;;chr1:44513995..44514031,+!p1@KLF17!0.81!5.42!KLF17;;chrX:131622958..131622978,-!p3@MBNL3!0.80!6.87!MBNL3;;chr6:126240356..126240379,+!p7@NCOA7!0.80!6.68!NCOA7;;chr13:100623375..100623425,-!p1@ZIC5!0.80!5.32!ZIC5;;chr21:38071430..38071456,+!p1@SIM2!0.79!5.22!SIM2;;chr12:54332652..54332671,+!p2@HOXC13!0.79!5.13!HOXC13;;chr1:117602932..117602973,+!p1@TTF2!0.78!20.32!TTF2;;chr3:138665937..138665968,-!p1@FOXL2!0.78!5.03!FOXL2;;chr1:23885981..23886002,-!p1@ID3!0.77!941.54!ID3;;chr12:52445218..52445237,+!p1@NR4A1!0.77!68.21!NR4A1;;chr12:54410664..54410684,+!p1@HOXC4,p1@HOXC5,p1@HOXC6!0.77!4.93!HOXC5;;chr12:54366949..54366973,+!p3@HOXC11!0.76!4.74!HOXC11;;chr20:32274179..32274213,-!p1@E2F1!0.75!33.96!E2F1;;chr20:32274150..32274166,-!p2@E2F1!0.74!8.90!E2F1;;chr19:2867325..2867348,+!p1@ZNF556!0.74!4.45!ZNF556;;chr9:99180617..99180658,-!p1@ZNF367!0.73!10.16!ZNF367;;chr13:73636516..73636532,+!p3@KLF5!0.73!5.13!KLF5;;chr6:126240463..126240489,+!p6@NCOA7!0.72!4.84!NCOA7;;chr15:66994615..66994630,+!p3@SMAD6!0.71!6.19!SMAD6;;chr3:69915369..69915381,+!p4@MITF!0.71!4.16!MITF;;chr1:45805872..45805900,+!p2@TOE1!0.70!10.64!TOE1;;chr15:41913690..41913753,+!p2@MGA!0.70!10.55!MGA;;chr16:29818199..29818216,+!p11@MAZ!0.70!6.97!MAZ;;chr13:73636252..73636307,+!p2@KLF5!0.70!4.74!KLF5;;chr5:134369643..134369675,-!p4@PITX1!0.70!4.06!PITX1;;chr5:170736216..170736238,+!p2@TLX3!0.70!4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|fonse_cell_line=FF:0101120 | |fonse_cell_line=FF:0101120 | ||
|fonse_cell_line_closure=FF:0101120 | |fonse_cell_line_closure=FF:0101120 | ||
Line 66: | Line 39: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/epitheloid%2520carcinoma%2520cell%2520line%253a%2520HelaS3%2520ENCODE%252c%2520biol_rep1.CNhs12325.10815-111B5.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/epitheloid%2520carcinoma%2520cell%2520line%253a%2520HelaS3%2520ENCODE%252c%2520biol_rep1.CNhs12325.10815-111B5.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/epitheloid%2520carcinoma%2520cell%2520line%253a%2520HelaS3%2520ENCODE%252c%2520biol_rep1.CNhs12325.10815-111B5.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/epitheloid%2520carcinoma%2520cell%2520line%253a%2520HelaS3%2520ENCODE%252c%2520biol_rep1.CNhs12325.10815-111B5.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/epitheloid%2520carcinoma%2520cell%2520line%253a%2520HelaS3%2520ENCODE%252c%2520biol_rep1.CNhs12325.10815-111B5.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10815-111B5 | |||
|is_a=EFO:0002091;;FF:0011472 | |||
|is_obsolete= | |||
|library_id=CNhs12325 | |||
|library_id_phase_based=2:CNhs12325 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10815 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10815 | |||
|name=epitheloid carcinoma cell line: HelaS3 ENCODE, biol_rep1 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs12325,LSID913,release011,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.0200550750766617,0,0,0,0,-0.0182336393265531,0.248966015065766,-0.167093955755268,0.502941110114757,0,0,0,0,0,0,0,0,0,0,0,0.0768270310165508,0,0.0180469873752344,0,0,0,0,0,0.291446536051737,0,0,0.273260099751048,0,0,0,0,0,0,0,0,0,0,0,0,-0.0963289888768802,0.135793824031289,0,0,0,0,0,0,0,0.0614699777489965,0,0,0,0,0,0,0.0401101501533233,0.384720070519709,0,0,0.0740263705105651,0,0,0,0,0,0,0,0,0.0401101501533233,0,0,0,0,0,0,0,0,0,0.055340130488326,0,0.0559434009706216,0,0,0,-0.0900487628078253,0,0,0,0.096984025047889,-0.155857272207543,0.0200550750766617,0,0,0,0.173993630730781,0.492773068013623,0,0,0,0.0401101501533233,0,0,0.0401101501533233,0,0,0,0,0,0,0,0,0,0,0.462171552796053,0.612381429029588,0,0,-0.010279483345994,-0.0981813543558379,0,0,0.156955386540382,0,0,0 | |||
|repeat_enrich_byname=0,0.334670035345502,0,0.0401101501533233,0.173993630730781,0,0,0.272028981968487,0,0,0,0,0.0768270310165508,0,0,0,-0.136498614308913,0,0.186777766499144,0.128513839445015,0,0,0.127609163095278,0,0.110680260976652,0,0,0,0,0.0401101501533233,0,0,-0.0880097167992414,0,0.148392386843301,0,0,0,0,-0.0186252810838506,-0.305472230898407,0,-0.0382435701652662,0.0423359998992834,0,0,0,0,-0.0375913124101235,0,-0.010199222817089,0.0886498294002448,-0.221611588102807,-0.645892176970687,-0.055712496781182,0,0,0,-0.524115055874225,0.255852042666383,0,0,-0.121779851751874,-0.181349618560659,0,0,-0.391044581551635,0,-0.14237998026273,-0.059654134622041,0,0.268039462816123,0,0,0,0,0,0,0,0,0,0,0,-0.0574934668214365,0.563596896929361,0.0388100699961874,0,0,0,-0.189397054582214,0,0,0.558527235025305,-0.0787070313283715,-0.0517626490836696,-0.165203077291803,0,-0.302389727009913,-0.182999649075866,-0.302865729204774,0.121854540700307,-0.147401849371139,-0.189981719549847,0,-0.0100721879515431,-0.396868196794218,0.020583437272594,-0.0900487628078253,-0.0178780244078962,-0.608887899510698,0.172934195290384,0,0,0.0401101501533233,-0.0606701661654071,0,0,0.0184682773294901,-0.066598809691714,-0.162776572218938,-0.121796093820284,0.206925961502256,-0.251691193816511,-0.0395325284566706,-0.315352062136762,0,-0.210371175061768,0,0,-0.0476412755493996,0.0239832769455781,0.52060963244983,-0.281156137833177,0,0.0113780329091429,-0.0683442610773682,0,-0.106173871751029,-0.245614510472201,0,-0.0025139767375435,-0.125708177887989,0,0,0.243195134165073,0,0.0401101501533233,0.242692636546898,-0.133275453500256,-0.0340506231229288,0,0.079219648295696,0.000421542977618816,0.160619197918451,0,0.0677438096672832,-0.0914905006341539,0.0556175305978602,-0.181953543619584,0,0.16893842523216,0.244874731322372,0.0117794574274503,-0.311714544415086,0.0836375639480078,0.083449877780588,-0.0567898328790502,0.096984025047889,-0.366537565106362,-0.0525020596952186,-0.0881268324752877,-0.0568806519758174,-0.843434600365057,0.0721122574711749,0,-0.227183076978773,0,-0.384820610930369,0,0.17687663800284,0.0200550750766617,-0.0115616568863041,0.0919947147320305,-0.00128307126552868,0.296932226824669,0,-0.298582240429413,-0.494202221649235,0,0,0,0,-0.150367083334639,0.181940610097492,-0.191595352787927,-0.0029749656949511,0.0637369392888353,-0.322453316284046,0,0,-0.181739694981152,0.285943454873776,0.0401101501533233,-0.227674212206498,-0.186800614529532,-0.310287325070555,-0.115971073434934,0.110680260976652,0,0.341432552926566,0,0,0.523812302074705,0,-0.57967317380531,-0.213216191333432,-0.0855950638182295,-0.108622809454255,0,0,0.331055225841088,0.0401101501533233,-0.447048393117662,0,0.0401101501533233,-0.0645034230281784,0,0,0,0,0,0,0,0,0,0,0,0,-0.228021947527303,0.411417114273009,0,0,0,0.0768270310165508,0,0,0.0401101501533233,-0.00957768809788515,0,0,-0.186142463282538,-0.115525012587001,-0.082907265523097,0,0,0,0,0.279632092166649,-0.0925563011180722,0,0.162066009627108,0,0,0,0,0.0559434009706216,0,0,0,0.0384135155082754,-0.0176203069003407,-0.0987515946302595,0,0,0,0.61363109200654,0,0,0,0,-0.137303408584277,0,0,-0.023280662930528,0,-0.0914287107301113,0.0290983814298102,0,0.15689265183584,-0.293184699168462,-0.0490093557117532,0,0,0.092344551169265,0,0,0.217693078272283,-0.00554319194911546,0.371915044020705,0,0,0,0,0,0.0401101501533233,0,0.0796142037249836,0,0,0.036166267391685,0,0,0,0,0.0401101501533233,0,0,0,-0.227613078469715,0.132385219371943,0.0401101501533233,0,0,0,0,0,0,0.0343625675060339,0.147932935564066,0,0,0.0200550750766617,0,0,0.0401101501533233,0,0,0.198517341321433,0,0,0,0,0,0.384720070519709,0,0,0,0.0401101501533233,0.807077281796897,0,0,-0.135277741433681,0,0.0316608211632443,0,0,0,0,0.0401101501533233,0.0401101501533233,0,0,0.0293966087849567,0,0,0.125646929030319,-0.167093955755268,0,0.110680260976652,0,0,0,0.248966015065766,0,-0.19800626718954,0,0.198804938432616,0,0,0.0282000170508558,0,0,0,-0.0646862346358331,0,-0.0182336393265531,0,0,0,0,0,0.0401101501533233,0.0384135155082754,0,0,0,0,0,0,0,0,0,0,0,0.185957522010353,0,0,-0.153059755211347,0,-0.145123125213077,0,0,0,0.068371580712575,0,0,0,0,0,0,0.054344574833304,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.00292595888539873,0,0,0.612381429029588,0,0,0,0,0,0,0.0638512226574735,0,0,0,0,0,0,0,0.291446536051737,0,0,-0.0920328098005262,0,0,0.0156334605591747,0.0768270310165508,0,0,-0.120332072153156,0.032993833279488,-0.0486878312525318,0,0,0.0401101501533233,-0.0159720569741796,0,0,0,0.0401101501533233,0.0100496435976495,0,0,0,0,0,0,0,0,0.0401101501533233,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0584685905849371,0,0,0,0,0.0180469873752344,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0910972704565782,0,0,0,0,0,0,0.122058202785489,0,0,0.0401101501533233,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0401101501533233,0.234758477087397,0,0,0,-0.136259198640493,0,0,0,0,0,0,0.0401101501533233,0,0.495355494720124,0,0,0,0,0,0,0,0,0,0,0.622520608776406,0.0401101501533233,0,0,0,0,0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| |||
|rna_box=111 | |||
|rna_catalog_number= | |||
|rna_concentration=0.76591 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.13 | |||
|rna_od260/280=2.02 | |||
|rna_position=B5 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=111B5 | |||
|rna_weight_ug=38.2955 | |||
|sample_age= | |||
|sample_category=cell lines | |||
|sample_cell_catalog= | |||
|sample_cell_line=HelaS3 | |||
|sample_cell_lot= | |||
|sample_cell_type=epithelial cell | |||
|sample_collaboration=Carrie Davis (Cold spring Harbor Laboratories) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.20938270214917e-281!GO:0043226;organelle;7.17260051869375e-236!GO:0043229;intracellular organelle;2.78323382341384e-235!GO:0043227;membrane-bound organelle;1.79540440679134e-234!GO:0043231;intracellular membrane-bound organelle;1.79540440679134e-234!GO:0005737;cytoplasm;9.51444955918604e-188!GO:0044422;organelle part;6.33817174875765e-185!GO:0044446;intracellular organelle part;5.3246301637839e-183!GO:0044444;cytoplasmic part;1.31016261737962e-133!GO:0032991;macromolecular complex;4.41459691237111e-124!GO:0044237;cellular metabolic process;1.79461603271622e-110!GO:0005634;nucleus;4.59872149974805e-110!GO:0030529;ribonucleoprotein complex;9.50408468481755e-106!GO:0044238;primary metabolic process;1.37936611887301e-105!GO:0044428;nuclear part;3.49861990141842e-103!GO:0043233;organelle lumen;1.12835472458265e-98!GO:0031974;membrane-enclosed lumen;1.12835472458265e-98!GO:0043170;macromolecule metabolic process;6.07520243725918e-95!GO:0003723;RNA binding;5.06473820586438e-91!GO:0005739;mitochondrion;8.74782473799091e-88!GO:0005515;protein binding;2.27346695980488e-72!GO:0006396;RNA processing;1.20679761533993e-68!GO:0031981;nuclear lumen;3.67644913825898e-62!GO:0043234;protein complex;6.5070462943365e-62!GO:0005840;ribosome;2.94848465764489e-61!GO:0006412;translation;6.42921212151432e-60!GO:0044429;mitochondrial part;3.90945223053948e-58!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.02665349736093e-57!GO:0043283;biopolymer metabolic process;5.24725782007154e-57!GO:0031967;organelle envelope;2.9690519615268e-54!GO:0031975;envelope;4.91534293136488e-54!GO:0031090;organelle membrane;7.37984988921387e-53!GO:0006259;DNA metabolic process;9.74396134290789e-53!GO:0003735;structural constituent of ribosome;3.65009640159953e-52!GO:0010467;gene expression;8.99769817159191e-52!GO:0044249;cellular biosynthetic process;1.80362904319773e-51!GO:0016043;cellular component organization and biogenesis;9.56918645485806e-49!GO:0043228;non-membrane-bound organelle;1.28200944228935e-48!GO:0043232;intracellular non-membrane-bound organelle;1.28200944228935e-48!GO:0019538;protein metabolic process;1.69906445257258e-48!GO:0016071;mRNA metabolic process;2.57274535191459e-48!GO:0009058;biosynthetic process;1.16395957638311e-47!GO:0008380;RNA splicing;2.33230552049299e-44!GO:0044267;cellular protein metabolic process;3.79247616815815e-44!GO:0033279;ribosomal subunit;3.79247616815815e-44!GO:0044260;cellular macromolecule metabolic process;1.15879246117189e-43!GO:0006397;mRNA processing;3.21986209620701e-43!GO:0006996;organelle organization and biogenesis;5.29947657580145e-43!GO:0009059;macromolecule biosynthetic process;4.18345274597453e-41!GO:0033036;macromolecule localization;1.43332899982314e-40!GO:0015031;protein transport;3.84419014000516e-40!GO:0005829;cytosol;4.95798539007061e-40!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.39843494026433e-38!GO:0005654;nucleoplasm;3.65189762025739e-37!GO:0007049;cell cycle;4.75766667968214e-37!GO:0005740;mitochondrial envelope;7.98153018308748e-37!GO:0019866;organelle inner membrane;2.54529688768425e-36!GO:0008104;protein localization;5.20842128200256e-36!GO:0045184;establishment of protein localization;5.25400124853321e-36!GO:0065003;macromolecular complex assembly;1.27119704824212e-35!GO:0031966;mitochondrial membrane;5.5557039927864e-35!GO:0003676;nucleic acid binding;2.27093543604153e-34!GO:0046907;intracellular transport;4.24925944072138e-34!GO:0005743;mitochondrial inner membrane;8.23975836410149e-34!GO:0000166;nucleotide binding;1.41278421172699e-33!GO:0005681;spliceosome;1.7213311292888e-32!GO:0022607;cellular component assembly;8.80802378249707e-32!GO:0006974;response to DNA damage stimulus;2.37485377194988e-31!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.75451198773059e-30!GO:0005694;chromosome;6.78168548460984e-30!GO:0000278;mitotic cell cycle;5.3869376188719e-29!GO:0044451;nucleoplasm part;6.38804488125297e-29!GO:0022402;cell cycle process;1.082436851696e-27!GO:0005730;nucleolus;1.2035768700077e-27!GO:0006281;DNA repair;3.12430084259989e-27!GO:0006886;intracellular protein transport;3.71035173692741e-27!GO:0031980;mitochondrial lumen;9.73618712527881e-27!GO:0005759;mitochondrial matrix;9.73618712527881e-27!GO:0044427;chromosomal part;1.60956162667415e-26!GO:0044445;cytosolic part;4.83252992749615e-26!GO:0016462;pyrophosphatase activity;6.37614783647889e-26!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;6.87447434187571e-26!GO:0016817;hydrolase activity, acting on acid anhydrides;1.11557834246421e-25!GO:0017111;nucleoside-triphosphatase activity;4.66022739726187e-25!GO:0006119;oxidative phosphorylation;7.73158156643965e-25!GO:0044455;mitochondrial membrane part;9.56332311827578e-25!GO:0006260;DNA replication;3.90813766507042e-24!GO:0006457;protein folding;4.26230918364032e-24!GO:0022403;cell cycle phase;1.3355230010519e-23!GO:0016874;ligase activity;1.56666503800069e-23!GO:0015934;large ribosomal subunit;2.01926880448164e-23!GO:0016070;RNA metabolic process;2.61417711403143e-23!GO:0009719;response to endogenous stimulus;3.39609274550494e-23!GO:0032553;ribonucleotide binding;5.36649664124645e-23!GO:0032555;purine ribonucleotide binding;5.36649664124645e-23!GO:0017076;purine nucleotide binding;1.13490676585626e-22!GO:0000087;M phase of mitotic cell cycle;1.26924220752255e-22!GO:0005524;ATP binding;1.26924220752255e-22!GO:0032559;adenyl ribonucleotide binding;1.73001558111494e-22!GO:0051276;chromosome organization and biogenesis;2.03089776638884e-22!GO:0007067;mitosis;3.25246263580485e-22!GO:0015935;small ribosomal subunit;7.62358209613323e-22!GO:0030554;adenyl nucleotide binding;7.7449359765152e-22!GO:0051649;establishment of cellular localization;1.74285572752153e-21!GO:0051641;cellular localization;4.18353465365435e-21!GO:0042254;ribosome biogenesis and assembly;2.58655412593724e-20!GO:0012505;endomembrane system;6.52637706663138e-20!GO:0051301;cell division;2.10654324925166e-19!GO:0000279;M phase;3.25835170726921e-19!GO:0005746;mitochondrial respiratory chain;3.4200656185904e-19!GO:0022618;protein-RNA complex assembly;4.39917236482862e-19!GO:0051186;cofactor metabolic process;7.55259818216652e-19!GO:0005783;endoplasmic reticulum;1.39318229959309e-18!GO:0044265;cellular macromolecule catabolic process;1.92124035795336e-18!GO:0006512;ubiquitin cycle;1.97016967162049e-18!GO:0016887;ATPase activity;1.97016967162049e-18!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;3.27958727463741e-18!GO:0000502;proteasome complex (sensu Eukaryota);5.9978574661257e-18!GO:0005761;mitochondrial ribosome;7.6924231384334e-18!GO:0000313;organellar ribosome;7.6924231384334e-18!GO:0044453;nuclear membrane part;8.21870278495565e-18!GO:0005635;nuclear envelope;1.05667822956621e-17!GO:0042623;ATPase activity, coupled;1.97527195683735e-17!GO:0008134;transcription factor binding;2.0821077108739e-17!GO:0031965;nuclear membrane;2.2640822572065e-17!GO:0008135;translation factor activity, nucleic acid binding;3.71272725293179e-17!GO:0006399;tRNA metabolic process;4.24582491076129e-17!GO:0050136;NADH dehydrogenase (quinone) activity;4.25626988787856e-17!GO:0003954;NADH dehydrogenase activity;4.25626988787856e-17!GO:0008137;NADH dehydrogenase (ubiquinone) activity;4.25626988787856e-17!GO:0044432;endoplasmic reticulum part;4.53085741587771e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;4.97279251240621e-17!GO:0019941;modification-dependent protein catabolic process;9.01768536486273e-17!GO:0043632;modification-dependent macromolecule catabolic process;9.01768536486273e-17!GO:0006511;ubiquitin-dependent protein catabolic process;1.12606046814394e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;1.24341321563928e-16!GO:0044257;cellular protein catabolic process;1.56848417924388e-16!GO:0051082;unfolded protein binding;1.94427594724742e-16!GO:0044248;cellular catabolic process;1.95273294007825e-16!GO:0000398;nuclear mRNA splicing, via spliceosome;2.59828165770363e-16!GO:0000375;RNA splicing, via transesterification reactions;2.59828165770363e-16!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.59828165770363e-16!GO:0006323;DNA packaging;3.3526467155056e-16!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);4.62426171778237e-16!GO:0005643;nuclear pore;6.84838841404961e-16!GO:0043285;biopolymer catabolic process;9.38038075955921e-16!GO:0006605;protein targeting;1.3103613368224e-15!GO:0006732;coenzyme metabolic process;1.337685049785e-15!GO:0042775;organelle ATP synthesis coupled electron transport;1.70906401065622e-15!GO:0042773;ATP synthesis coupled electron transport;1.70906401065622e-15!GO:0009057;macromolecule catabolic process;4.97849079328043e-15!GO:0030964;NADH dehydrogenase complex (quinone);5.11449251128565e-15!GO:0045271;respiratory chain complex I;5.11449251128565e-15!GO:0005747;mitochondrial respiratory chain complex I;5.11449251128565e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);6.27352132775799e-15!GO:0004386;helicase activity;9.56984439097421e-15!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.46141543401999e-14!GO:0050657;nucleic acid transport;2.31181874070311e-14!GO:0051236;establishment of RNA localization;2.31181874070311e-14!GO:0050658;RNA transport;2.31181874070311e-14!GO:0006364;rRNA processing;2.62415635067348e-14!GO:0006403;RNA localization;2.76661868349903e-14!GO:0016604;nuclear body;4.34780341237539e-14!GO:0000785;chromatin;6.14399628775293e-14!GO:0016072;rRNA metabolic process;8.08203147182551e-14!GO:0046930;pore complex;8.71586251167354e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.58551002564291e-13!GO:0065002;intracellular protein transport across a membrane;1.84481399016237e-13!GO:0042175;nuclear envelope-endoplasmic reticulum network;3.33630019022756e-13!GO:0048770;pigment granule;4.88349931000864e-13!GO:0042470;melanosome;4.88349931000864e-13!GO:0005789;endoplasmic reticulum membrane;5.83031294066461e-13!GO:0043412;biopolymer modification;7.8386503079005e-13!GO:0003743;translation initiation factor activity;8.9455187016242e-13!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.07183614062024e-12!GO:0051726;regulation of cell cycle;1.41184683875031e-12!GO:0006366;transcription from RNA polymerase II promoter;1.47690676464574e-12!GO:0006333;chromatin assembly or disassembly;1.81255758102669e-12!GO:0030163;protein catabolic process;1.87995774382885e-12!GO:0006913;nucleocytoplasmic transport;1.95852447180886e-12!GO:0065004;protein-DNA complex assembly;2.26693985252757e-12!GO:0000074;regulation of progression through cell cycle;2.36864361934613e-12!GO:0051028;mRNA transport;2.5455265258106e-12!GO:0008026;ATP-dependent helicase activity;5.86620293448492e-12!GO:0051169;nuclear transport;6.0552920983592e-12!GO:0006261;DNA-dependent DNA replication;7.8967926398079e-12!GO:0012501;programmed cell death;9.82463153155241e-12!GO:0009055;electron carrier activity;1.10595583370274e-11!GO:0003712;transcription cofactor activity;1.43946280887917e-11!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.7347146817378e-11!GO:0004812;aminoacyl-tRNA ligase activity;1.7347146817378e-11!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.7347146817378e-11!GO:0006915;apoptosis;1.81150087957728e-11!GO:0006413;translational initiation;2.12394301821343e-11!GO:0009259;ribonucleotide metabolic process;2.88031265097553e-11!GO:0016879;ligase activity, forming carbon-nitrogen bonds;3.07153527519562e-11!GO:0048193;Golgi vesicle transport;3.07794260536988e-11!GO:0016607;nuclear speck;3.26667439658304e-11!GO:0051188;cofactor biosynthetic process;3.90237914566067e-11!GO:0043038;amino acid activation;3.90237914566067e-11!GO:0006418;tRNA aminoacylation for protein translation;3.90237914566067e-11!GO:0043039;tRNA aminoacylation;3.90237914566067e-11!GO:0016568;chromatin modification;4.95892241766806e-11!GO:0006163;purine nucleotide metabolic process;5.3226974495127e-11!GO:0000775;chromosome, pericentric region;5.85048398203047e-11!GO:0016779;nucleotidyltransferase activity;1.62156827810331e-10!GO:0043566;structure-specific DNA binding;1.82992618659589e-10!GO:0006446;regulation of translational initiation;2.08104881263112e-10!GO:0008219;cell death;2.93510561694849e-10!GO:0016265;death;2.93510561694849e-10!GO:0006464;protein modification process;3.01285810966467e-10!GO:0006164;purine nucleotide biosynthetic process;3.96890431586032e-10!GO:0003697;single-stranded DNA binding;5.68310597783128e-10!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;5.82460757831826e-10!GO:0009260;ribonucleotide biosynthetic process;5.96272718058904e-10!GO:0007005;mitochondrion organization and biogenesis;6.23966422779583e-10!GO:0009150;purine ribonucleotide metabolic process;8.95360133363623e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.0357969186777e-09!GO:0008565;protein transporter activity;1.16836479483587e-09!GO:0009108;coenzyme biosynthetic process;1.55499635628815e-09!GO:0005819;spindle;1.90816590813308e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.05342266957507e-09!GO:0008639;small protein conjugating enzyme activity;2.14028849588818e-09!GO:0015630;microtubule cytoskeleton;2.32755378235151e-09!GO:0006461;protein complex assembly;2.59059718538006e-09!GO:0017038;protein import;2.90650216444372e-09!GO:0043687;post-translational protein modification;3.05038507587632e-09!GO:0016787;hydrolase activity;3.60823502630122e-09!GO:0030532;small nuclear ribonucleoprotein complex;5.29214640804134e-09!GO:0009060;aerobic respiration;5.50374760309012e-09!GO:0004842;ubiquitin-protein ligase activity;6.29182239223806e-09!GO:0009152;purine ribonucleotide biosynthetic process;6.77309418283571e-09!GO:0019787;small conjugating protein ligase activity;7.00088998657226e-09!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;7.32331213601485e-09!GO:0015986;ATP synthesis coupled proton transport;9.86435881951036e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;9.86435881951036e-09!GO:0016192;vesicle-mediated transport;9.92615538062025e-09!GO:0009199;ribonucleoside triphosphate metabolic process;9.92615538062025e-09!GO:0051325;interphase;1.02634963629041e-08!GO:0051329;interphase of mitotic cell cycle;1.04904235234502e-08!GO:0009141;nucleoside triphosphate metabolic process;1.14139057872132e-08!GO:0045333;cellular respiration;1.18511103333616e-08!GO:0005794;Golgi apparatus;1.29534615033643e-08!GO:0009056;catabolic process;1.30982716515364e-08!GO:0007051;spindle organization and biogenesis;1.64549853116389e-08!GO:0005657;replication fork;1.85144674355429e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.41105183231392e-08!GO:0009144;purine nucleoside triphosphate metabolic process;2.41105183231392e-08!GO:0009142;nucleoside triphosphate biosynthetic process;2.60997572084071e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.60997572084071e-08!GO:0006752;group transfer coenzyme metabolic process;2.68765715102098e-08!GO:0015078;hydrogen ion transmembrane transporter activity;2.68765715102098e-08!GO:0016881;acid-amino acid ligase activity;3.15408691143045e-08!GO:0016740;transferase activity;4.14903619290484e-08!GO:0046034;ATP metabolic process;4.29741327708225e-08!GO:0006334;nucleosome assembly;5.14608785823124e-08!GO:0005667;transcription factor complex;6.33107410089839e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;6.69535774611259e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;6.69535774611259e-08!GO:0031497;chromatin assembly;7.21538790439932e-08!GO:0005793;ER-Golgi intermediate compartment;7.74275101867215e-08!GO:0019829;cation-transporting ATPase activity;7.9930520541248e-08!GO:0006754;ATP biosynthetic process;8.6183420432895e-08!GO:0006753;nucleoside phosphate metabolic process;8.6183420432895e-08!GO:0043623;cellular protein complex assembly;1.18144991295313e-07!GO:0008094;DNA-dependent ATPase activity;1.29029945150172e-07!GO:0016469;proton-transporting two-sector ATPase complex;1.35940326071715e-07!GO:0009117;nucleotide metabolic process;1.46229538244393e-07!GO:0000245;spliceosome assembly;1.67553463513423e-07!GO:0003899;DNA-directed RNA polymerase activity;2.05855601646744e-07!GO:0000075;cell cycle checkpoint;2.37742235318451e-07!GO:0008033;tRNA processing;2.5993286033635e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;3.25036697917343e-07!GO:0006099;tricarboxylic acid cycle;3.29914403787125e-07!GO:0046356;acetyl-CoA catabolic process;3.29914403787125e-07!GO:0005839;proteasome core complex (sensu Eukaryota);3.52712400835458e-07!GO:0005813;centrosome;3.64788284528708e-07!GO:0045259;proton-transporting ATP synthase complex;4.34655443892106e-07!GO:0016741;transferase activity, transferring one-carbon groups;4.97245276674795e-07!GO:0003713;transcription coactivator activity;5.14794770525769e-07!GO:0042981;regulation of apoptosis;5.5158703316156e-07!GO:0008168;methyltransferase activity;5.586645617769e-07!GO:0006084;acetyl-CoA metabolic process;6.01694315668708e-07!GO:0032446;protein modification by small protein conjugation;6.52699773388839e-07!GO:0006302;double-strand break repair;7.10835209611053e-07!GO:0043067;regulation of programmed cell death;7.17926802241894e-07!GO:0005768;endosome;7.31664014090391e-07!GO:0005815;microtubule organizing center;7.48210904426358e-07!GO:0016567;protein ubiquitination;9.49991033485593e-07!GO:0003724;RNA helicase activity;1.17391029063885e-06!GO:0044452;nucleolar part;1.24896060019354e-06!GO:0016853;isomerase activity;1.31386669127255e-06!GO:0004298;threonine endopeptidase activity;1.64649831790606e-06!GO:0051170;nuclear import;1.97645572084511e-06!GO:0016491;oxidoreductase activity;2.06871038158447e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;2.06878195985053e-06!GO:0003682;chromatin binding;2.07855372423104e-06!GO:0005762;mitochondrial large ribosomal subunit;2.50255585170907e-06!GO:0000315;organellar large ribosomal subunit;2.50255585170907e-06!GO:0051427;hormone receptor binding;2.84921787278419e-06!GO:0006414;translational elongation;3.06526219390193e-06!GO:0051187;cofactor catabolic process;3.40095403120548e-06!GO:0009109;coenzyme catabolic process;3.94978713864992e-06!GO:0006888;ER to Golgi vesicle-mediated transport;4.04807962436019e-06!GO:0016564;transcription repressor activity;4.52289955750752e-06!GO:0007059;chromosome segregation;4.89817783123954e-06!GO:0000151;ubiquitin ligase complex;5.17097911374438e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;5.71014718044099e-06!GO:0030120;vesicle coat;6.37639644195512e-06!GO:0030662;coated vesicle membrane;6.37639644195512e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;6.58758317487143e-06!GO:0035257;nuclear hormone receptor binding;6.62701157537098e-06!GO:0051168;nuclear export;6.78646661607658e-06!GO:0000776;kinetochore;7.56523294479763e-06!GO:0000079;regulation of cyclin-dependent protein kinase activity;7.80866699600387e-06!GO:0006606;protein import into nucleus;7.89733332397217e-06!GO:0048475;coated membrane;8.13449978972976e-06!GO:0030117;membrane coat;8.13449978972976e-06!GO:0051246;regulation of protein metabolic process;8.13449978972976e-06!GO:0046483;heterocycle metabolic process;8.48710640026573e-06!GO:0006091;generation of precursor metabolites and energy;9.63174426386702e-06!GO:0006613;cotranslational protein targeting to membrane;9.99597130589044e-06!GO:0000314;organellar small ribosomal subunit;1.0012175979669e-05!GO:0005763;mitochondrial small ribosomal subunit;1.0012175979669e-05!GO:0043069;negative regulation of programmed cell death;1.06325255881656e-05!GO:0008654;phospholipid biosynthetic process;1.07283068072256e-05!GO:0006916;anti-apoptosis;1.08226274015616e-05!GO:0019752;carboxylic acid metabolic process;1.20081624168108e-05!GO:0003690;double-stranded DNA binding;1.21066111341061e-05!GO:0006082;organic acid metabolic process;1.40638605273397e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;1.44455296662659e-05!GO:0043066;negative regulation of apoptosis;1.4961191496124e-05!GO:0006793;phosphorus metabolic process;1.54182027869571e-05!GO:0006796;phosphate metabolic process;1.54182027869571e-05!GO:0006310;DNA recombination;1.6001477314555e-05!GO:0005788;endoplasmic reticulum lumen;1.60312893361315e-05!GO:0051052;regulation of DNA metabolic process;1.6214392735168e-05!GO:0016859;cis-trans isomerase activity;1.83924499180497e-05!GO:0050794;regulation of cellular process;2.08973444779103e-05!GO:0004518;nuclease activity;2.53837495390126e-05!GO:0006839;mitochondrial transport;2.63916031547415e-05!GO:0031324;negative regulation of cellular metabolic process;2.71849572142451e-05!GO:0016363;nuclear matrix;2.95117825057156e-05!GO:0006626;protein targeting to mitochondrion;3.14213692326552e-05!GO:0004527;exonuclease activity;3.58921388861894e-05!GO:0000226;microtubule cytoskeleton organization and biogenesis;3.72870867475413e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;3.86217721120069e-05!GO:0003684;damaged DNA binding;4.05346521835697e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;4.35194622352312e-05!GO:0015399;primary active transmembrane transporter activity;4.35194622352312e-05!GO:0006352;transcription initiation;4.67065740068122e-05!GO:0000059;protein import into nucleus, docking;5.23549537352875e-05!GO:0008186;RNA-dependent ATPase activity;5.5353317692302e-05!GO:0007088;regulation of mitosis;5.85643824099668e-05!GO:0009165;nucleotide biosynthetic process;6.46423295062067e-05!GO:0016563;transcription activator activity;6.65788339275664e-05!GO:0045454;cell redox homeostasis;7.30160729972195e-05!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;7.31324402825575e-05!GO:0000786;nucleosome;7.55309311417433e-05!GO:0043021;ribonucleoprotein binding;7.9394746835982e-05!GO:0031072;heat shock protein binding;8.47629716269238e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;8.81369888211844e-05!GO:0048523;negative regulation of cellular process;8.81369888211844e-05!GO:0006270;DNA replication initiation;9.05719027785967e-05!GO:0005770;late endosome;9.28007793340025e-05!GO:0043681;protein import into mitochondrion;9.46348370934569e-05!GO:0005753;mitochondrial proton-transporting ATP synthase complex;9.86467654711151e-05!GO:0003714;transcription corepressor activity;0.000101866378929964!GO:0007052;mitotic spindle organization and biogenesis;0.000105563720316811!GO:0044440;endosomal part;0.0001132444113314!GO:0010008;endosome membrane;0.0001132444113314!GO:0003924;GTPase activity;0.000120441302454679!GO:0016310;phosphorylation;0.000123333401225325!GO:0003678;DNA helicase activity;0.000131454003779097!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.000153861532910066!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.000156447417722298!GO:0004004;ATP-dependent RNA helicase activity;0.000170040687147308!GO:0003729;mRNA binding;0.000176079981056113!GO:0030880;RNA polymerase complex;0.000193014962478499!GO:0015980;energy derivation by oxidation of organic compounds;0.000199192421772055!GO:0032508;DNA duplex unwinding;0.000200954952019164!GO:0032392;DNA geometric change;0.000200954952019164!GO:0019222;regulation of metabolic process;0.000204806185046824!GO:0005798;Golgi-associated vesicle;0.000205053602375638!GO:0043596;nuclear replication fork;0.000220074014472099!GO:0009892;negative regulation of metabolic process;0.00024060862147006!GO:0009112;nucleobase metabolic process;0.000242959162330448!GO:0006402;mRNA catabolic process;0.000254808031919898!GO:0006612;protein targeting to membrane;0.000259696969554491!GO:0042802;identical protein binding;0.000291930264633302!GO:0051789;response to protein stimulus;0.000305217489301119!GO:0006986;response to unfolded protein;0.000305217489301119!GO:0045786;negative regulation of progression through cell cycle;0.000315284072858184!GO:0016251;general RNA polymerase II transcription factor activity;0.000315284072858184!GO:0006284;base-excision repair;0.000333462312432765!GO:0046474;glycerophospholipid biosynthetic process;0.000362802835917278!GO:0000049;tRNA binding;0.00037362730154257!GO:0006401;RNA catabolic process;0.000398331880187129!GO:0048471;perinuclear region of cytoplasm;0.000398913963384644!GO:0005791;rough endoplasmic reticulum;0.000402963184681341!GO:0005684;U2-dependent spliceosome;0.000409766107538167!GO:0050662;coenzyme binding;0.000452138059056428!GO:0006520;amino acid metabolic process;0.000454507360099515!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000471856884934905!GO:0000428;DNA-directed RNA polymerase complex;0.000471856884934905!GO:0051920;peroxiredoxin activity;0.000474199036208431!GO:0006268;DNA unwinding during replication;0.000491716573089202!GO:0030867;rough endoplasmic reticulum membrane;0.000496278882837902!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000503287614084213!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000506098127956729!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000506098127956729!GO:0019867;outer membrane;0.000523305676544694!GO:0003711;transcription elongation regulator activity;0.000547167743189169!GO:0031968;organelle outer membrane;0.000549375981170801!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.000574537573598109!GO:0000819;sister chromatid segregation;0.000588499160404258!GO:0000070;mitotic sister chromatid segregation;0.00060935047308496!GO:0006950;response to stress;0.000617331952273233!GO:0005048;signal sequence binding;0.000622100195065465!GO:0006405;RNA export from nucleus;0.000681500277282649!GO:0043492;ATPase activity, coupled to movement of substances;0.000681500277282649!GO:0007093;mitotic cell cycle checkpoint;0.000689336310703929!GO:0051252;regulation of RNA metabolic process;0.000689336310703929!GO:0019899;enzyme binding;0.00070062967637826!GO:0003746;translation elongation factor activity;0.000722956441954249!GO:0006275;regulation of DNA replication;0.000726631885248675!GO:0033116;ER-Golgi intermediate compartment membrane;0.000771360114527234!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000771360114527234!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000771360114527234!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000771360114527234!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000826665790306094!GO:0043601;nuclear replisome;0.000849038892678499!GO:0030894;replisome;0.000849038892678499!GO:0007017;microtubule-based process;0.000924397934568245!GO:0046489;phosphoinositide biosynthetic process;0.000930125190139892!GO:0006383;transcription from RNA polymerase III promoter;0.000930125190139892!GO:0043284;biopolymer biosynthetic process;0.000941462043380853!GO:0005874;microtubule;0.000954433590445406!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000958000373123482!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000980165108337657!GO:0019843;rRNA binding;0.000990119274570391!GO:0005773;vacuole;0.00101522778287251!GO:0048519;negative regulation of biological process;0.00102249329912037!GO:0015631;tubulin binding;0.00102249329912037!GO:0022890;inorganic cation transmembrane transporter activity;0.00105506331208173!GO:0006595;polyamine metabolic process;0.00114324596898517!GO:0005741;mitochondrial outer membrane;0.00114657268567958!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00114737949493125!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00114737949493125!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00115405171824623!GO:0005876;spindle microtubule;0.00115829458069396!GO:0051087;chaperone binding;0.0011651075187013!GO:0000096;sulfur amino acid metabolic process;0.00117892617517346!GO:0000228;nuclear chromosome;0.00121919108814149!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00127133074589334!GO:0007010;cytoskeleton organization and biogenesis;0.00127591433146578!GO:0000922;spindle pole;0.00129437135058761!GO:0048037;cofactor binding;0.00133281416285204!GO:0003702;RNA polymerase II transcription factor activity;0.00138907376940151!GO:0043414;biopolymer methylation;0.00143692682596733!GO:0009451;RNA modification;0.0014575851153703!GO:0008312;7S RNA binding;0.0014594697152184!GO:0005637;nuclear inner membrane;0.00153654128514753!GO:0048500;signal recognition particle;0.00160165546312449!GO:0015992;proton transport;0.0016214238188347!GO:0044431;Golgi apparatus part;0.00162474413183404!GO:0008022;protein C-terminus binding;0.00166399435589886!GO:0016481;negative regulation of transcription;0.00171628981902655!GO:0048487;beta-tubulin binding;0.00173622303894127!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00174763538358317!GO:0005885;Arp2/3 protein complex;0.00176084545746156!GO:0008408;3'-5' exonuclease activity;0.00183652226244046!GO:0009116;nucleoside metabolic process;0.00184251762923264!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00184304967934632!GO:0006818;hydrogen transport;0.00185064900510735!GO:0032259;methylation;0.00188522763100235!GO:0016272;prefoldin complex;0.00192137060943816!GO:0051540;metal cluster binding;0.00204656974654736!GO:0051536;iron-sulfur cluster binding;0.00204656974654736!GO:0051287;NAD binding;0.00211054120041264!GO:0006289;nucleotide-excision repair;0.00211706463521245!GO:0042393;histone binding;0.00219033744802397!GO:0006144;purine base metabolic process;0.00219033744802397!GO:0005769;early endosome;0.00228190658050225!GO:0042770;DNA damage response, signal transduction;0.00228243483855621!GO:0007006;mitochondrial membrane organization and biogenesis;0.00235285016571269!GO:0008250;oligosaccharyl transferase complex;0.00250829022499661!GO:0005525;GTP binding;0.00265408563296476!GO:0004576;oligosaccharyl transferase activity;0.00267265035073622!GO:0035258;steroid hormone receptor binding;0.00267986858691968!GO:0032200;telomere organization and biogenesis;0.002717523125884!GO:0000723;telomere maintenance;0.002717523125884!GO:0030521;androgen receptor signaling pathway;0.00275696719396658!GO:0000323;lytic vacuole;0.00278359929860545!GO:0005764;lysosome;0.00278359929860545!GO:0031124;mRNA 3'-end processing;0.00280407809522893!GO:0006519;amino acid and derivative metabolic process;0.00286477892161062!GO:0008139;nuclear localization sequence binding;0.00297075118545117!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00317668434675441!GO:0031252;leading edge;0.00337025181572457!GO:0000082;G1/S transition of mitotic cell cycle;0.00338234434403394!GO:0016126;sterol biosynthetic process;0.00339589941480481!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00352847388783936!GO:0000178;exosome (RNase complex);0.00354705740005562!GO:0065009;regulation of a molecular function;0.00355505769804853!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00355777456162088!GO:0000725;recombinational repair;0.0037133257143475!GO:0000724;double-strand break repair via homologous recombination;0.0037133257143475!GO:0046966;thyroid hormone receptor binding;0.0037378695822387!GO:0006611;protein export from nucleus;0.00376383450431112!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00396974655855517!GO:0048522;positive regulation of cellular process;0.00414191475075213!GO:0008610;lipid biosynthetic process;0.00414347916480397!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00431522203976862!GO:0045047;protein targeting to ER;0.00431522203976862!GO:0043488;regulation of mRNA stability;0.00434583912487168!GO:0043487;regulation of RNA stability;0.00434583912487168!GO:0008276;protein methyltransferase activity;0.00436836985722408!GO:0006338;chromatin remodeling;0.00446291186549796!GO:0008632;apoptotic program;0.00449138620347827!GO:0006650;glycerophospholipid metabolic process;0.00465319744731758!GO:0000086;G2/M transition of mitotic cell cycle;0.00473845680660357!GO:0005758;mitochondrial intermembrane space;0.00484173310764085!GO:0006695;cholesterol biosynthetic process;0.004870696528993!GO:0030658;transport vesicle membrane;0.00496539291656125!GO:0003725;double-stranded RNA binding;0.0052345781976256!GO:0031323;regulation of cellular metabolic process;0.00526136520088934!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00535441800603109!GO:0046467;membrane lipid biosynthetic process;0.0058719926897095!GO:0005669;transcription factor TFIID complex;0.00596007165788242!GO:0006506;GPI anchor biosynthetic process;0.0059688098834738!GO:0006400;tRNA modification;0.00602245056369208!GO:0008180;signalosome;0.00617526522377453!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00619540938818575!GO:0009124;nucleoside monophosphate biosynthetic process;0.00630639902331689!GO:0009123;nucleoside monophosphate metabolic process;0.00630639902331689!GO:0006118;electron transport;0.00636972909478898!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00649882956702692!GO:0051053;negative regulation of DNA metabolic process;0.00657306558895017!GO:0030384;phosphoinositide metabolic process;0.00657480838105595!GO:0050789;regulation of biological process;0.0066841411905576!GO:0043624;cellular protein complex disassembly;0.00708973388307343!GO:0006378;mRNA polyadenylation;0.00708973388307343!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00712768813393388!GO:0015002;heme-copper terminal oxidase activity;0.00712768813393388!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00712768813393388!GO:0004129;cytochrome-c oxidase activity;0.00712768813393388!GO:0000781;chromosome, telomeric region;0.00735901496382197!GO:0000287;magnesium ion binding;0.00770951244083185!GO:0031123;RNA 3'-end processing;0.00790149316691016!GO:0004674;protein serine/threonine kinase activity;0.00794507245349068!GO:0000339;RNA cap binding;0.00800038772580718!GO:0043022;ribosome binding;0.00800570193088474!GO:0031570;DNA integrity checkpoint;0.00803772731912571!GO:0005832;chaperonin-containing T-complex;0.00814305340417655!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00817665344940977!GO:0004003;ATP-dependent DNA helicase activity;0.00824736505410263!GO:0003887;DNA-directed DNA polymerase activity;0.00830496652880936!GO:0006505;GPI anchor metabolic process;0.00831366807000649!GO:0040029;regulation of gene expression, epigenetic;0.00834228175534501!GO:0030663;COPI coated vesicle membrane;0.00857963781914756!GO:0030126;COPI vesicle coat;0.00857963781914756!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00864628556413343!GO:0005663;DNA replication factor C complex;0.00877236663139586!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00879765508493883!GO:0022411;cellular component disassembly;0.00893486941777873!GO:0030660;Golgi-associated vesicle membrane;0.00896613393626599!GO:0006376;mRNA splice site selection;0.00958359799615358!GO:0000389;nuclear mRNA 3'-splice site recognition;0.00958359799615358!GO:0018196;peptidyl-asparagine modification;0.00969926007909502!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00969926007909502!GO:0043065;positive regulation of apoptosis;0.00974276438188333!GO:0006891;intra-Golgi vesicle-mediated transport;0.00975947133076837!GO:0032984;macromolecular complex disassembly;0.00997952408828322!GO:0009119;ribonucleoside metabolic process;0.0101778416895209!GO:0006497;protein amino acid lipidation;0.0104202140101347!GO:0030118;clathrin coat;0.0104701370476931!GO:0006730;one-carbon compound metabolic process;0.0105631592374067!GO:0016197;endosome transport;0.0106463879891006!GO:0030132;clathrin coat of coated pit;0.0110825447619188!GO:0031988;membrane-bound vesicle;0.0113040364154682!GO:0004532;exoribonuclease activity;0.0113777204081468!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0113777204081468!GO:0030176;integral to endoplasmic reticulum membrane;0.0114422993544303!GO:0051539;4 iron, 4 sulfur cluster binding;0.0114818690672305!GO:0000792;heterochromatin;0.0121949550322229!GO:0007021;tubulin folding;0.0123139752146717!GO:0030137;COPI-coated vesicle;0.0126122697782986!GO:0000139;Golgi membrane;0.0127470138199982!GO:0006767;water-soluble vitamin metabolic process;0.0129910137360607!GO:0006596;polyamine biosynthetic process;0.0132183563431471!GO:0000080;G1 phase of mitotic cell cycle;0.0132255031185518!GO:0008017;microtubule binding;0.0132846064696494!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0133531516533655!GO:0043068;positive regulation of programmed cell death;0.0133762306895862!GO:0004523;ribonuclease H activity;0.0134084447304428!GO:0005905;coated pit;0.0134729082241147!GO:0043241;protein complex disassembly;0.0134858767432092!GO:0031970;organelle envelope lumen;0.0138471484300064!GO:0008637;apoptotic mitochondrial changes;0.0138471484300064!GO:0009161;ribonucleoside monophosphate metabolic process;0.0139758184476508!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0139758184476508!GO:0030518;steroid hormone receptor signaling pathway;0.0141446469997578!GO:0016788;hydrolase activity, acting on ester bonds;0.0142381029868345!GO:0000910;cytokinesis;0.0145822959303233!GO:0032561;guanyl ribonucleotide binding;0.0146952864640084!GO:0019001;guanyl nucleotide binding;0.0146952864640084!GO:0046983;protein dimerization activity;0.0146954039488419!GO:0006007;glucose catabolic process;0.0148253073653857!GO:0008170;N-methyltransferase activity;0.0151297539949908!GO:0000726;non-recombinational repair;0.0151786333467211!GO:0016023;cytoplasmic membrane-bound vesicle;0.0154032244626649!GO:0050681;androgen receptor binding;0.0154032244626649!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.015801269937587!GO:0046112;nucleobase biosynthetic process;0.0159279056085534!GO:0007004;telomere maintenance via telomerase;0.0159640375069752!GO:0005869;dynactin complex;0.0160179736318246!GO:0009303;rRNA transcription;0.0164417700807969!GO:0007034;vacuolar transport;0.0166260087271239!GO:0006417;regulation of translation;0.0168200473564105!GO:0030134;ER to Golgi transport vesicle;0.0169659005993301!GO:0006360;transcription from RNA polymerase I promoter;0.017069238673457!GO:0016790;thiolester hydrolase activity;0.0175734775092295!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0179125269889664!GO:0035267;NuA4 histone acetyltransferase complex;0.0182674554005763!GO:0044454;nuclear chromosome part;0.0185089692311278!GO:0008361;regulation of cell size;0.0185604278751359!GO:0019783;small conjugating protein-specific protease activity;0.0185604278751359!GO:0008538;proteasome activator activity;0.0186492588711212!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.0186867936902141!GO:0006350;transcription;0.0189256235722479!GO:0046982;protein heterodimerization activity;0.0190071822078182!GO:0016407;acetyltransferase activity;0.0190071822078182!GO:0031577;spindle checkpoint;0.0193515521743469!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0201351395585195!GO:0008156;negative regulation of DNA replication;0.020407330656565!GO:0017166;vinculin binding;0.0205901658973209!GO:0006213;pyrimidine nucleoside metabolic process;0.0205901658973209!GO:0043433;negative regulation of transcription factor activity;0.0207494801809161!GO:0004659;prenyltransferase activity;0.0210651868613056!GO:0031902;late endosome membrane;0.0212955319335918!GO:0006541;glutamine metabolic process;0.0217473712076499!GO:0006733;oxidoreduction coenzyme metabolic process;0.0224347880072699!GO:0004540;ribonuclease activity;0.022516887997474!GO:0005732;small nucleolar ribonucleoprotein complex;0.0229931907769057!GO:0043189;H4/H2A histone acetyltransferase complex;0.0234368021804326!GO:0007050;cell cycle arrest;0.0239186866318082!GO:0044438;microbody part;0.0239819119745094!GO:0044439;peroxisomal part;0.0239819119745094!GO:0000152;nuclear ubiquitin ligase complex;0.0241684365760866!GO:0005862;muscle thin filament tropomyosin;0.0245478699294215!GO:0031982;vesicle;0.024669727711085!GO:0004843;ubiquitin-specific protease activity;0.0251577156253302!GO:0047485;protein N-terminus binding;0.0251917342611585!GO:0030433;ER-associated protein catabolic process;0.0254671086929346!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0254671086929346!GO:0006354;RNA elongation;0.0256340463919406!GO:0005658;alpha DNA polymerase:primase complex;0.0256762933735297!GO:0004536;deoxyribonuclease activity;0.0257290123584393!GO:0008234;cysteine-type peptidase activity;0.0258613619152285!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0261740307361091!GO:0010257;NADH dehydrogenase complex assembly;0.0261740307361091!GO:0033108;mitochondrial respiratory chain complex assembly;0.0261740307361091!GO:0030508;thiol-disulfide exchange intermediate activity;0.0262638600906442!GO:0004526;ribonuclease P activity;0.0264668773558238!GO:0008320;protein transmembrane transporter activity;0.026535394015425!GO:0006807;nitrogen compound metabolic process;0.026535394015425!GO:0016049;cell growth;0.0268619023380469!GO:0051059;NF-kappaB binding;0.0269947290912035!GO:0006740;NADPH regeneration;0.0274347183557729!GO:0006098;pentose-phosphate shunt;0.0274347183557729!GO:0000097;sulfur amino acid biosynthetic process;0.0274718260600054!GO:0043154;negative regulation of caspase activity;0.0276768775031815!GO:0006458;'de novo' protein folding;0.0276768775031815!GO:0051084;'de novo' posttranslational protein folding;0.0276768775031815!GO:0006778;porphyrin metabolic process;0.0277017712997978!GO:0033013;tetrapyrrole metabolic process;0.0277017712997978!GO:0051716;cellular response to stimulus;0.0278045472428114!GO:0042158;lipoprotein biosynthetic process;0.0278045472428114!GO:0006509;membrane protein ectodomain proteolysis;0.0278045472428114!GO:0033619;membrane protein proteolysis;0.0278045472428114!GO:0007243;protein kinase cascade;0.0278045472428114!GO:0030261;chromosome condensation;0.0283007171349167!GO:0046128;purine ribonucleoside metabolic process;0.0287074697040664!GO:0042278;purine nucleoside metabolic process;0.0287074697040664!GO:0004549;tRNA-specific ribonuclease activity;0.0288785350953982!GO:0042054;histone methyltransferase activity;0.029226406859621!GO:0006406;mRNA export from nucleus;0.0293969034303625!GO:0031326;regulation of cellular biosynthetic process;0.0294320409757617!GO:0051318;G1 phase;0.0294353378796177!GO:0033170;DNA-protein loading ATPase activity;0.0296642608940317!GO:0003689;DNA clamp loader activity;0.0296642608940317!GO:0016044;membrane organization and biogenesis;0.0296642608940317!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0297674679387351!GO:0045039;protein import into mitochondrial inner membrane;0.0297674679387351!GO:0045892;negative regulation of transcription, DNA-dependent;0.0299052083222643!GO:0046519;sphingoid metabolic process;0.0303239799063338!GO:0016408;C-acyltransferase activity;0.0303245441729115!GO:0000175;3'-5'-exoribonuclease activity;0.0303568303051525!GO:0008629;induction of apoptosis by intracellular signals;0.0303568303051525!GO:0044450;microtubule organizing center part;0.0305271274460758!GO:0009889;regulation of biosynthetic process;0.0308251975362197!GO:0022884;macromolecule transmembrane transporter activity;0.0309943569745353!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0309943569745353!GO:0032039;integrator complex;0.0313145750441212!GO:0000077;DNA damage checkpoint;0.0314527273261374!GO:0000123;histone acetyltransferase complex;0.0314527273261374!GO:0044262;cellular carbohydrate metabolic process;0.0315609320291968!GO:0030125;clathrin vesicle coat;0.0315713452243867!GO:0030665;clathrin coated vesicle membrane;0.0315713452243867!GO:0008097;5S rRNA binding;0.0316438101867966!GO:0006278;RNA-dependent DNA replication;0.0317168955566117!GO:0006301;postreplication repair;0.0317252202811312!GO:0005784;translocon complex;0.0318404593149011!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0322758865729474!GO:0031625;ubiquitin protein ligase binding;0.0323918588894139!GO:0043631;RNA polyadenylation;0.032528016760114!GO:0008652;amino acid biosynthetic process;0.0328236448797984!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0328236448797984!GO:0005487;nucleocytoplasmic transporter activity;0.0333124207313984!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0333651076391909!GO:0000793;condensed chromosome;0.0339574781932019!GO:0006379;mRNA cleavage;0.0342262869740635!GO:0015036;disulfide oxidoreductase activity;0.0343361949542734!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0345831560370036!GO:0042026;protein refolding;0.0347687034988476!GO:0031410;cytoplasmic vesicle;0.0347687034988476!GO:0030127;COPII vesicle coat;0.0347687034988476!GO:0012507;ER to Golgi transport vesicle membrane;0.0347687034988476!GO:0050790;regulation of catalytic activity;0.0351073586832221!GO:0007041;lysosomal transport;0.0351867984372356!GO:0000119;mediator complex;0.035347600516733!GO:0031903;microbody membrane;0.0353760317378163!GO:0005778;peroxisomal membrane;0.0353760317378163!GO:0001522;pseudouridine synthesis;0.0358114179847664!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0359219227327894!GO:0051320;S phase;0.0359983753121011!GO:0007346;regulation of progression through mitotic cell cycle;0.0363167931057644!GO:0033673;negative regulation of kinase activity;0.0363167931057644!GO:0006469;negative regulation of protein kinase activity;0.0363167931057644!GO:0001558;regulation of cell growth;0.036392047612897!GO:0004861;cyclin-dependent protein kinase inhibitor activity;0.0365647629485447!GO:0017134;fibroblast growth factor binding;0.0365701674467474!GO:0030503;regulation of cell redox homeostasis;0.0375324011582443!GO:0008426;protein kinase C inhibitor activity;0.0375776277817232!GO:0006672;ceramide metabolic process;0.0378618427739491!GO:0006220;pyrimidine nucleotide metabolic process;0.0381260347992682!GO:0051338;regulation of transferase activity;0.0381947542884514!GO:0000030;mannosyltransferase activity;0.0387514547835353!GO:0030119;AP-type membrane coat adaptor complex;0.0391793729508033!GO:0042769;DNA damage response, detection of DNA damage;0.0393929533583033!GO:0004221;ubiquitin thiolesterase activity;0.0394326843581287!GO:0004722;protein serine/threonine phosphatase activity;0.0397471485997386!GO:0000118;histone deacetylase complex;0.040233874669167!GO:0022406;membrane docking;0.040233874669167!GO:0048278;vesicle docking;0.040233874669167!GO:0051348;negative regulation of transferase activity;0.0403388644185101!GO:0030131;clathrin adaptor complex;0.0403695381380223!GO:0003923;GPI-anchor transamidase activity;0.0403695381380223!GO:0016255;attachment of GPI anchor to protein;0.0403695381380223!GO:0042765;GPI-anchor transamidase complex;0.0403695381380223!GO:0031371;ubiquitin conjugating enzyme complex;0.0409353133457058!GO:0031529;ruffle organization and biogenesis;0.0409353133457058!GO:0008287;protein serine/threonine phosphatase complex;0.0410042728365593!GO:0017056;structural constituent of nuclear pore;0.0413934845868151!GO:0006979;response to oxidative stress;0.0414948713575353!GO:0019206;nucleoside kinase activity;0.0416408580597082!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.042769677612044!GO:0016569;covalent chromatin modification;0.0429356987590564!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.0429828907690623!GO:0000303;response to superoxide;0.0433561340422289!GO:0030659;cytoplasmic vesicle membrane;0.0438986194826322!GO:0007040;lysosome organization and biogenesis;0.043970456850672!GO:0006779;porphyrin biosynthetic process;0.0443224971001492!GO:0033014;tetrapyrrole biosynthetic process;0.0443224971001492!GO:0051085;chaperone cofactor-dependent protein folding;0.0445823810115!GO:0005652;nuclear lamina;0.0449393599699926!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0459045793592369!GO:0008537;proteasome activator complex;0.0460527375661865!GO:0009308;amine metabolic process;0.0461899801654502!GO:0000305;response to oxygen radical;0.0464664902898725!GO:0030262;apoptotic nuclear changes;0.046595964096095!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0468104516194516!GO:0045936;negative regulation of phosphate metabolic process;0.0471050526738169!GO:0043549;regulation of kinase activity;0.0471515245368921!GO:0000209;protein polyubiquitination;0.0472679450335577!GO:0009066;aspartate family amino acid metabolic process;0.04735794937696!GO:0030036;actin cytoskeleton organization and biogenesis;0.0474421356322688!GO:0001889;liver development;0.0481695257016053!GO:0050811;GABA receptor binding;0.0489357556640408!GO:0003893;epsilon DNA polymerase activity;0.049777356863792!GO:0019318;hexose metabolic process;0.0498288212123871!GO:0005996;monosaccharide metabolic process;0.0498288212123871!GO:0009113;purine base biosynthetic process;0.0498757564937827 | |||
|sample_id=10815 | |||
|sample_note= | |||
|sample_sex=female | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=cervix | |||
|top_motifs=ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:2.14952121247;E2F1..5:1.97048122569;FOXD3:1.66725221359;ELK1,4_GABP{A,B1}:1.51501290189;YY1:1.48694692831;NFY{A,B,C}:1.3958210405;FOXQ1:1.37176949599;PITX1..3:1.36345349252;ZNF143:1.30297748185;HOX{A6,A7,B6,B7}:1.28737933867;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.26919241033;TFDP1:1.23739219526;ESRRA:1.15221271079;TOPORS:1.12628103504;NRF1:1.10167114362;POU2F1..3:1.09062211436;ZNF148:1.04344284586;MYB:1.03103971824;bHLH_family:1.02181878413;AIRE:0.981607582385;PAX8:0.89249533351;ZBTB16:0.886447207952;NR5A1,2:0.868342710845;NR6A1:0.837139198133;TEF:0.816235726017;PPARG:0.803118810256;FOX{I1,J2}:0.793900144953;POU3F1..4:0.792025134995;GFI1:0.771811871384;VSX1,2:0.759980328746;ARID5B:0.736404665759;SOX{8,9,10}:0.710305216463;HNF4A_NR2F1,2:0.619264674755;PAX1,9:0.607702829915;NKX3-2:0.594640695386;FOXN1:0.508167880096;FOXP1:0.486700468297;POU1F1:0.482536017456;CDX1,2,4:0.473422014736;IKZF1:0.471660083112;FOXM1:0.462254982996;HBP1_HMGB_SSRP1_UBTF:0.438059197223;BREu{core}:0.435096075722;CUX2:0.413789961006;PAX3,7:0.405390108059;NFIX:0.366624279527;ELF1,2,4:0.366045421443;PAX4:0.349707444934;NKX2-1,4:0.344783049682;EVI1:0.343438407529;STAT5{A,B}:0.335269326167;HOXA9_MEIS1:0.309670011126;TLX2:0.303564247576;ZNF384:0.301079254473;RFX2..5_RFXANK_RFXAP:0.295928648727;PBX1:0.291462572791;NKX3-1:0.249571883241;NFE2L2:0.244656783965;HES1:0.241542428541;RORA:0.237840317758;SNAI1..3:0.224831879888;TEAD1:0.22406168165;HSF1,2:0.21891532701;ZEB1:0.214216443049;OCT4_SOX2{dimer}:0.206680976745;FOXA2:0.194930475925;CDC5L:0.185688658417;PDX1:0.180589913613;MYOD1:0.156219644075;ALX1:0.145845467296;UFEwm:0.130532093057;GCM1,2:0.128028239204;NR1H4:0.12143213003;TBX4,5:0.104541877288;ATF5_CREB3:0.0768675644776;NKX6-1,2:0.0764467424395;IRF7:0.0706461861426;NFE2L1:0.0615952683637;HOX{A5,B5}:0.0516206046689;PRRX1,2:0.023681021549;FOXL1:0.017936136984;FOX{F1,F2,J1}:-0.000878984018486;NFE2:-0.00687820290691;CEBPA,B_DDIT3:-0.0204030354501;GTF2A1,2:-0.0238463291874;IKZF2:-0.0328353324875;BPTF:-0.0631298968686;AHR_ARNT_ARNT2:-0.0635413542976;AR:-0.0704071793165;BACH2:-0.0855207460534;POU6F1:-0.0864946266332;RXRA_VDR{dimer}:-0.0883817469914;HNF1A:-0.0902818715955;GFI1B:-0.107096031699;CREB1:-0.118027066185;EN1,2:-0.120156947737;ZNF423:-0.127049769662;HLF:-0.13967521776;PAX2:-0.144712667972;DBP:-0.147780961419;GATA6:-0.148715674254;LMO2:-0.173482595432;KLF4:-0.174545177469;FOS_FOS{B,L1}_JUN{B,D}:-0.185258148394;ESR1:-0.198605101639;EP300:-0.220956841478;MYBL2:-0.226663602345;ONECUT1,2:-0.228482764007;ZBTB6:-0.229519784204;TLX1..3_NFIC{dimer}:-0.239804858161;RFX1:-0.245666907282;GZF1:-0.254795694028;JUN:-0.267580159009;HOX{A4,D4}:-0.296046297584;LHX3,4:-0.297303194072;ATF4:-0.312619663837;FOSL2:-0.317376871901;POU5F1:-0.332301054587;LEF1_TCF7_TCF7L1,2:-0.345470799649;FOXO1,3,4:-0.35218855877;TBP:-0.353701822193;PAX5:-0.386882649179;RBPJ:-0.389091937711;MEF2{A,B,C,D}:-0.405070617447;HIF1A:-0.40974924137;NFKB1_REL_RELA:-0.411629560591;FOXP3:-0.440217662787;SPIB:-0.451985789355;STAT2,4,6:-0.45372576311;MTF1:-0.453773921176;ZFP161:-0.463680705144;NANOG:-0.471052791531;RXR{A,B,G}:-0.477491041121;TP53:-0.484479748434;HAND1,2:-0.48691041142;SOX5:-0.513390225547;NR3C1:-0.523849809856;SPI1:-0.548685631019;EBF1:-0.554518099624;DMAP1_NCOR{1,2}_SMARC:-0.56034257566;NFIL3:-0.574316852502;MED-1{core}:-0.578031831008;HIC1:-0.585700279219;GTF2I:-0.614220459803;FOX{D1,D2}:-0.617824004051;CRX:-0.623164735329;XCPE1{core}:-0.6322729962;SREBF1,2:-0.638750695595;HMGA1,2:-0.642733416461;GLI1..3:-0.653306172557;RUNX1..3:-0.657936174059;IRF1,2:-0.667830540742;ADNP_IRX_SIX_ZHX:-0.668241286788;ALX4:-0.679129125467;PAX6:-0.684295812649;GATA4:-0.706824488922;REST:-0.709191145793;TFAP2B:-0.715184833067;TAL1_TCF{3,4,12}:-0.723793623075;STAT1,3:-0.756066394596;SOX2:-0.79194507576;ETS1,2:-0.811572768784;NKX2-3_NKX2-5:-0.815583069984;PRDM1:-0.852223650594;TFAP2{A,C}:-0.864192440032;RREB1:-0.901697842045;NKX2-2,8:-0.909639516016;NHLH1,2:-0.921053562486;SOX17:-0.921859197366;SP1:-0.930323655799;ZIC1..3:-0.935589358822;PATZ1:-0.970028657375;EGR1..3:-0.999563353087;MYFfamily:-1.03980730703;MAZ:-1.08207348806;XBP1:-1.08215442952;SRF:-1.09012020469;TFCP2:-1.09207056449;ATF2:-1.13587848064;ZNF238:-1.14990025174;NANOG{mouse}:-1.15317968598;NFATC1..3:-1.28043777082;T:-1.29279748632;MZF1:-1.29608592694;ATF6:-1.30297655627;MTE{core}:-1.30504244266;MAFB:-1.34316132169;TGIF1:-1.39299748478;TFAP4:-1.46725303281;SMAD1..7,9:-1.74895544139;SPZ1:-1.95557361612;HMX1:-2.26897926699 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10815-111B5;search_select_hide=table117:FF:10815-111B5 | |||
}} | }} |
Latest revision as of 15:06, 3 June 2020
Name: | epitheloid carcinoma cell line: HelaS3 ENCODE, biol_rep1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs12325 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12325
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12325
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.131 |
10 | 10 | 0.0463 |
100 | 100 | 0.0497 |
101 | 101 | 0.895 |
102 | 102 | 0.94 |
103 | 103 | 0.188 |
104 | 104 | 0.932 |
105 | 105 | 0.369 |
106 | 106 | 0.0523 |
107 | 107 | 0.105 |
108 | 108 | 0.444 |
109 | 109 | 0.0349 |
11 | 11 | 0.796 |
110 | 110 | 0.193 |
111 | 111 | 0.552 |
112 | 112 | 0.00609 |
113 | 113 | 0.0216 |
114 | 114 | 0.715 |
115 | 115 | 0.787 |
116 | 116 | 0.433 |
117 | 117 | 0.058 |
118 | 118 | 0.829 |
119 | 119 | 0.873 |
12 | 12 | 0.912 |
120 | 120 | 0.465 |
121 | 121 | 0.621 |
122 | 122 | 0.569 |
123 | 123 | 0.457 |
124 | 124 | 0.29 |
125 | 125 | 0.665 |
126 | 126 | 0.898 |
127 | 127 | 0.888 |
128 | 128 | 0.0127 |
129 | 129 | 0.407 |
13 | 13 | 4.79676e-5 |
130 | 130 | 0.109 |
131 | 131 | 0.0682 |
132 | 132 | 0.948 |
133 | 133 | 0.281 |
134 | 134 | 0.25 |
135 | 135 | 0.0751 |
136 | 136 | 0.0201 |
137 | 137 | 0.177 |
138 | 138 | 0.596 |
139 | 139 | 0.532 |
14 | 14 | 0.349 |
140 | 140 | 0.7 |
141 | 141 | 0.32 |
142 | 142 | 0.446 |
143 | 143 | 0.683 |
144 | 144 | 0.768 |
145 | 145 | 0.407 |
146 | 146 | 0.375 |
147 | 147 | 0.42 |
148 | 148 | 0.525 |
149 | 149 | 0.0894 |
15 | 15 | 0.954 |
150 | 150 | 0.666 |
151 | 151 | 0.888 |
152 | 152 | 0.0895 |
153 | 153 | 0.249 |
154 | 154 | 0.87 |
155 | 155 | 0.523 |
156 | 156 | 0.529 |
157 | 157 | 0.347 |
158 | 158 | 0.166 |
159 | 159 | 0.278 |
16 | 16 | 0.6 |
160 | 160 | 0.866 |
161 | 161 | 0.186 |
162 | 162 | 0.343 |
163 | 163 | 0.923 |
164 | 164 | 0.573 |
165 | 165 | 0.679 |
166 | 166 | 0.312 |
167 | 167 | 0.139 |
168 | 168 | 0.487 |
169 | 169 | 0.621 |
17 | 17 | 0.709 |
18 | 18 | 0.105 |
19 | 19 | 0.488 |
2 | 2 | 0.0985 |
20 | 20 | 0.03 |
21 | 21 | 0.763 |
22 | 22 | 0.689 |
23 | 23 | 0.0012 |
24 | 24 | 0.269 |
25 | 25 | 0.542 |
26 | 26 | 0.36 |
27 | 27 | 0.218 |
28 | 28 | 0.553 |
29 | 29 | 0.0316 |
3 | 3 | 0.903 |
30 | 30 | 0.0669 |
31 | 31 | 0.295 |
32 | 32 | 0.202 |
33 | 33 | 0.386 |
34 | 34 | 0.158 |
35 | 35 | 0.879 |
36 | 36 | 0.132 |
37 | 37 | 0.522 |
38 | 38 | 0.715 |
39 | 39 | 0.826 |
4 | 4 | 0.345 |
40 | 40 | 0.0554 |
41 | 41 | 0.175 |
42 | 42 | 0.559 |
43 | 43 | 0.591 |
44 | 44 | 0.87 |
45 | 45 | 0.327 |
46 | 46 | 0.861 |
47 | 47 | 0.4 |
48 | 48 | 0.434 |
49 | 49 | 0.867 |
5 | 5 | 0.466 |
50 | 50 | 0.907 |
51 | 51 | 0.408 |
52 | 52 | 0.145 |
53 | 53 | 0.66 |
54 | 54 | 0.518 |
55 | 55 | 0.0476 |
56 | 56 | 0.646 |
57 | 57 | 0.453 |
58 | 58 | 0.833 |
59 | 59 | 0.46 |
6 | 6 | 0.492 |
60 | 60 | 0.234 |
61 | 61 | 0.154 |
62 | 62 | 0.836 |
63 | 63 | 0.545 |
64 | 64 | 0.641 |
65 | 65 | 0.145 |
66 | 66 | 1.06875e-6 |
67 | 67 | 0.707 |
68 | 68 | 0.778 |
69 | 69 | 0.641 |
7 | 7 | 0.122 |
70 | 70 | 0.247 |
71 | 71 | 0.034 |
72 | 72 | 0.404 |
73 | 73 | 0.919 |
74 | 74 | 0.594 |
75 | 75 | 0.0361 |
76 | 76 | 0.178 |
77 | 77 | 0.755 |
78 | 78 | 0.212 |
79 | 79 | 0.461 |
8 | 8 | 0.457 |
80 | 80 | 0.0378 |
81 | 81 | 0.699 |
82 | 82 | 0.0506 |
83 | 83 | 0.501 |
84 | 84 | 0.508 |
85 | 85 | 0.0795 |
86 | 86 | 0.67 |
87 | 87 | 0.0428 |
88 | 88 | 0.587 |
89 | 89 | 0.13 |
9 | 9 | 0.246 |
90 | 90 | 0.074 |
91 | 91 | 0.00601 |
92 | 92 | 0.0984 |
93 | 93 | 0.901 |
94 | 94 | 0.265 |
95 | 95 | 0.0351 |
96 | 96 | 0.216 |
97 | 97 | 0.654 |
98 | 98 | 0.663 |
99 | 99 | 0.605 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12325
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011472 human epitheloid carcinoma cell line: HelaS3 ENCODE sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
305 (carcinoma)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100297 (carcinoma cell line sample)
0101120 (epithelial cell line sample)
0011472 (human epitheloid carcinoma cell line: HelaS3 ENCODE sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
NA