FF:10835-111D7: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet= | |DRA_sample_Accession=CAGE@SAMD00005061 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |accession_numbers=CAGE;DRX007817;DRR008689;DRZ000114;DRZ001499;DRZ011464;DRZ012849 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:8692 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0101883,FF:0100740 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score=chr3:128212033..128212051,-!p1@GATA2!2.56!363.32!GATA2;;chr12:54694758..54694805,-!p1@NFE2!1.88!90.20!NFE2;;chr18:77155922..77155939,+!p1@NFATC1!1.81!165.93!NFATC1;;chr3:128206762..128206781,-!p2@GATA2!1.72!304.85!GATA2;;chr13:72441315..72441454,-!p1@DACH1!1.70!94.94!DACH1;;chr9:135854091..135854159,+!p1@GFI1B!1.68!46.77!GFI1B;;chr7:137620684..137620711,-!p4@CREB3L2!1.61!40.09!CREB3L2;;chr6:135502501..135502546,+!p1@MYB!1.60!46.49!MYB;;chr17:40441354..40441410,+!p2@STAT5A!1.60!38.42!STAT5A;;chr12:54694807..54694832,-!p3@NFE2!1.59!37.86!NFE2;;chr7:137620650..137620677,-!p3@CREB3L2!1.56!35.64!CREB3L2;;chr6:135502408..135502459,+!p2@MYB!1.54!39.26!MYB;;chrX:48650688..48650735,+!p5@GATA1!1.48!28.95!GATA1;;chr19:46367576..46367592,+!p1@FOXA3!1.43!25.61!FOXA3;;chr19:13213511..13213545,-!p2@LYL1!1.40!26.45!LYL1;;chr12:54694653..54694672,-!p2@NFE2!1.25!16.70!NFE2;;chr17:40440177..40440190,+!p6@STAT5A!1.24!16.43!STAT5A;;chr11:44331576..44331650,-!p1@ALX4!1.23!15.87!ALX4;;chrY:21906594..21906622,-!p1@KDM5D!1.22!15.59!KDM5D;;chr20:61051039..61051057,-!p1@GATA5!1.16!13.36!GATA5;;chr9:20382446..20382493,-!p4@MLLT3!1.14!12.81!MLLT3;;chrX:131624056..131624069,-!p2@MBNL3!1.13!16.98!MBNL3;;chr4:81118647..81118666,+!p1@PRDM8!1.13!16.43!PRDM8;;chr11:44331679..44331702,-!p2@ALX4!1.13!12.53!ALX4;;chr12:54689532..54689551,-!p4@NFE2!1.11!11.97!NFE2;;chr9:127269661..127269719,-!p1@NR5A1!1.11!11.97!NR5A1;;chr21:36421535..36421610,-!p2@RUNX1!1.10!41.48!RUNX1;;chr16:68119324..68119364,+!p1@NFATC3!1.09!50.67!NFATC3;;chr1:25291475..25291511,-!p2@RUNX3!1.07!10.86!RUNX3;;chr11:113930425..113930471,+!p1@ZBTB16!1.06!15.03!ZBTB16;;chr7:50343634..50343717,+!p2@IKZF1!1.04!10.02!IKZF1;;chr8:37963466..37963506,+!p3@ASH2L!1.03!12.25!ASH2L;;chr10:124895472..124895508,+!p1@HMX3!1.03!9.74!HMX3;;chr13:72441074..72441172,-!p2@DACH1!1.03!9.74!DACH1;;chr11:32457103..32457123,-!p3@WT1!1.01!9.19!WT1;;chr13:79177703..79177729,-!p2@POU4F1!1.01!9.19!POU4F1;;chr8:80679993..80680011,-!p1@HEY1!0.99!12.81!HEY1;;chr9:135853402..135853417,+!p4@GFI1B!0.98!8.63!GFI1B;;chr2:239148671..239148686,-!p1@HES6!0.97!31.18!HES6;;chr1:158978768..158978800,+!p8@IFI16!0.97!8.35!IFI16;;chr6:20402102..20402152,+!p1@E2F3!0.96!34.24!E2F3;;chr11:113930291..113930339,+!p2@ZBTB16!0.96!13.64!ZBTB16;;chr10:94449703..94449718,+!p1@HHEX!0.95!31.18!HHEX;;chr13:79177674..79177701,-!p1@POU4F1!0.94!7.80!POU4F1;;chrY:2803415..2803468,+!p1@ZFY!0.94!7.80!ZFY;;chr10:35484053..35484076,+!p1@CREM!0.93!19.21!CREM;;chr11:32457075..32457095,-!p1@WT1!0.93!7.52!WT1;;chr2:219849897..219849928,-!p2@FEV!0.93!7.52!FEV;;chr6:135502472..135502489,+!p3@MYB!0.92!7.24!MYB;;chr17:41277372..41277418,-!p1@BRCA1!0.89!25.89!BRCA1;;chr11:63684602..63684664,-!p1@RCOR2!0.88!13.36!RCOR2;;chr17:41623692..41623715,-!p1@ETV4!0.87!28.68!ETV4;;chr6:28304275..28304282,-!p7@ZNF323!0.87!6.40!ZNF323;;chr1:3569072..3569093,+!p1@TP73!0.87!6.40!TP73;;chr8:22550982..22550999,-!p1@EGR3!0.86!18.37!EGR3;;chr16:88519743..88519754,+!p2@ZFPM1!0.85!6.68!ZFPM1;;chr3:69788576..69788648,+!p1@MITF!0.84!33.13!MITF;;chr5:137804405..137804444,+!p3@EGR1!0.84!7.24!EGR1;;chr20:42295745..42295765,+!p1@MYBL2!0.83!99.95!MYBL2;;chr4:53206..53260,+!p1@ZNF595,p1@ZNF718!0.83!58.47!ZNF595;;chr16:68118689..68118733,+!p3@NFATC3!0.83!15.31!NFATC3;;chr2:200322654..200322707,-!p2@SATB2!0.82!8.35!SATB2;;chr9:135854074..135854089,+!p2@GFI1B!0.82!5.57!GFI1B;;chr19:13213662..13213686,-!p1@LYL1!0.80!8.07!LYL1;;chr6:126070769..126070801,+!p1@HEY2!0.80!6.12!HEY2;;chr1:47697881..47697910,-!p4@TAL1!0.80!5.29!TAL1;;chr5:88178983..88179012,-!p1@MEF2C!0.79!43.15!MEF2C;;chr16:29818160..29818188,+!p6@MAZ!0.78!25.61!MAZ;;chr8:145669791..145669834,-!p1@TONSL!0.78!15.59!TONSL;;chr1:45805872..45805900,+!p2@TOE1!0.78!13.09!TOE1;;chr2:200323414..200323455,-!p1@SATB2!0.77!11.14!SATB2;;chr7:50344289..50344323,+!p1@IKZF1!0.76!4.73!IKZF1;;chr7:50348268..50348366,+!p4@IKZF1!0.76!4.73!IKZF1;;chr11:128457446..128457461,-!p4@ETS1!0.76!4.73!ETS1;;chr17:40440446..40440464,+!p5@STAT5A!0.76!4.73!STAT5A;;chr19:12998003..12998021,-!p1@KLF1!0.76!4.73!KLF1;;chr20:42295713..42295738,+!p2@MYBL2!0.75!30.35!MYBL2;;chr17:41622925..41622976,-!p3@ETV4!0.75!7.24!ETV4;;chr19:13213555..13213568,-!p5@LYL1!0.74!4.45!LYL1;;chr1:47691303..47691319,-!p5@TAL1!0.74!4.45!TAL1;;chr3:141747459..141747475,-!p1@TFDP2!0.73!40.37!TFDP2;;chr7:148581360..148581425,-!p1@EZH2!0.73!23.94!EZH2;;chr20:31350184..31350200,+!p1@DNMT3B!0.73!9.74!DNMT3B;;chr1:158985493..158985535,+!p4@IFI16!0.73!6.96!IFI16;;chr12:54785074..54785122,-!p2@ZNF385A!0.72!6.96!ZNF385A;;chr2:70314240..70314256,+!p4@PCBP1!0.71!9.19!PCBP1;;chrX:70316005..70316034,+!p2@FOXO4!0.71!8.07!FOXO4;;chrX:84499081..84499115,+!p2@ZNF711!0.71!6.40!ZNF711;;chr21:36260980..36261011,-!p1@RUNX1!0.70!133.36!RUNX1;;chr6:144329384..144329405,-!p1@PLAGL1!0.70!52.34!PLAGL1;;chr1:47779762..47779827,-!p1@STIL,p1@TAL1!0.70!20.32!TAL1;;chr2:74229812..74229867,+!p1@TET3!0.70!11.14!TET3;;chr19:12203100..12203132,+!p1@ZNF788!0.69!8.63!ZNF788;;chr11:19262421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| |||
|ffid_belonging_in_development=CL:0000049,CL:0000134 | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
Line 34: | Line 41: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M6%2529%2520cell%2520line%253aEEB.CNhs13059.10835-111D7.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M6%2529%2520cell%2520line%253aEEB.CNhs13059.10835-111D7.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M6%2529%2520cell%2520line%253aEEB.CNhs13059.10835-111D7.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M6%2529%2520cell%2520line%253aEEB.CNhs13059.10835-111D7.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M6%2529%2520cell%2520line%253aEEB.CNhs13059.10835-111D7.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10835-111D7 | |id=FF:10835-111D7 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0000210;;FF:0101883 | ||
|is_obsolete= | |||
|library_id=CNhs13059 | |||
|library_id_phase_based=2:CNhs13059 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10835 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10835 | |||
|name=acute myeloid leukemia (FAB M6) cell line:EEB | |name=acute myeloid leukemia (FAB M6) cell line:EEB | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
Line 41: | Line 60: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs13059,LSID1000,release012,COMPLETED | |profile_hcage=CNhs13059,LSID1000,release012,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,-0.160318030086386,0,0.0982919666886326,0.430146359046465,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.153323010348428,0,0,0,0.450460744394337,0,-0.0979578962680575,0,0,0.336695093018448,0,0,0,0,0,0,0.34499548838219,0,0,0,0,0,0.0338688485646987,0.0100771753469981,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0,0,-0.0499632213353613,0,-0.0969923612426051,0,0,0.09489264031293,0,0,0,0,0,0,0,0,0.106668859343321,0,0,0,0,0.192236267526027,0,0,0,0,0,0,0,0,0,0,-0.06817035280481,0,0,0,0.190097149815417,-0.0486834653984819,0.0533344296716605,0,0,0,-0.0980353512377064,0.251007402460986,0,0,0,0,0,0,0,0,0,0,0.2586320710604,0,0,0,0,0,0,0.0354702978952906,0.192236267526027,0,0,0.0265622025646352,0.072653466283317,0,0,0.0784638700555491,0,0,0 | |||
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| |||
|rna_box=111 | |rna_box=111 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
Line 56: | Line 78: | ||
|rna_weight_ug=143 | |rna_weight_ug=143 | ||
|sample_age=49 | |sample_age=49 | ||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB2345 | |sample_cell_catalog=RCB2345 | ||
|sample_cell_line=EEB | |sample_cell_line=EEB | ||
Line 68: | Line 91: | ||
|sample_ethnicity=unknown | |sample_ethnicity=unknown | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;7.76695641351219e-282!GO:0043226;organelle;7.14320101756769e-234!GO:0043229;intracellular organelle;3.21203255618767e-233!GO:0043227;membrane-bound organelle;1.32491775810309e-231!GO:0043231;intracellular membrane-bound organelle;3.16504328887916e-231!GO:0044422;organelle part;2.70026055924445e-184!GO:0044446;intracellular organelle part;7.42428336771246e-183!GO:0005737;cytoplasm;3.36500113208123e-174!GO:0044444;cytoplasmic part;7.35420198534395e-129!GO:0032991;macromolecular complex;1.45864307774871e-123!GO:0044237;cellular metabolic process;2.42913178156645e-119!GO:0005634;nucleus;1.04082405661601e-114!GO:0044238;primary metabolic process;4.2044646583259e-113!GO:0030529;ribonucleoprotein complex;2.22548370501499e-106!GO:0043170;macromolecule metabolic process;7.49150324929045e-105!GO:0044428;nuclear part;1.27371714196312e-100!GO:0003723;RNA binding;3.22382820101748e-95!GO:0043233;organelle lumen;3.74405279877048e-95!GO:0031974;membrane-enclosed lumen;3.74405279877048e-95!GO:0005739;mitochondrion;1.76258236538657e-86!GO:0006396;RNA processing;3.36483038553161e-66!GO:0043283;biopolymer metabolic process;8.99237715893498e-64!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.23286171326311e-63!GO:0043234;protein complex;9.61768226318241e-62!GO:0031981;nuclear lumen;1.6518742411241e-61!GO:0006412;translation;1.43113735568556e-60!GO:0005840;ribosome;5.43194160822376e-60!GO:0005515;protein binding;4.27141575896877e-58!GO:0044429;mitochondrial part;8.9526752494184e-58!GO:0006259;DNA metabolic process;8.9526752494184e-58!GO:0010467;gene expression;1.08750577962998e-55!GO:0031967;organelle envelope;1.63821355866931e-52!GO:0031975;envelope;4.17015229815132e-52!GO:0003735;structural constituent of ribosome;4.35070107163731e-52!GO:0016071;mRNA metabolic process;4.28084998552114e-51!GO:0009058;biosynthetic process;5.86882116952184e-51!GO:0009059;macromolecule biosynthetic process;6.5011156045789e-49!GO:0044249;cellular biosynthetic process;7.61849629820735e-49!GO:0031090;organelle membrane;9.24578439521098e-49!GO:0019538;protein metabolic process;1.95628421161812e-47!GO:0043228;non-membrane-bound organelle;2.15081657093639e-47!GO:0043232;intracellular non-membrane-bound organelle;2.15081657093639e-47!GO:0006996;organelle organization and biogenesis;1.79951704078698e-46!GO:0008380;RNA splicing;3.3265505570794e-45!GO:0016043;cellular component organization and biogenesis;1.57976615137596e-44!GO:0033279;ribosomal subunit;2.18834121097069e-44!GO:0006397;mRNA processing;2.82814174836795e-44!GO:0044267;cellular protein metabolic process;2.34381701895072e-43!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.73427703871163e-43!GO:0044260;cellular macromolecule metabolic process;9.00628509149441e-43!GO:0003676;nucleic acid binding;9.11534155039234e-43!GO:0007049;cell cycle;3.48009336024881e-42!GO:0005829;cytosol;4.75678741721628e-42!GO:0033036;macromolecule localization;5.06221760639129e-40!GO:0065003;macromolecular complex assembly;2.70499614980781e-39!GO:0015031;protein transport;6.51167275237372e-39!GO:0005654;nucleoplasm;6.0808231468127e-38!GO:0000166;nucleotide binding;2.0836060551664e-37!GO:0005740;mitochondrial envelope;9.24170101297088e-37!GO:0019866;organelle inner membrane;6.56814483136707e-36!GO:0008104;protein localization;3.36199398861612e-35!GO:0045184;establishment of protein localization;3.4973084918613e-35!GO:0046907;intracellular transport;3.98119184332131e-35!GO:0031966;mitochondrial membrane;3.22567951300204e-34!GO:0022607;cellular component assembly;3.96373729444959e-34!GO:0005681;spliceosome;7.38036811242635e-34!GO:0006974;response to DNA damage stimulus;8.13815579196677e-34!GO:0005743;mitochondrial inner membrane;7.6702951365385e-33!GO:0022402;cell cycle process;3.98592850177712e-32!GO:0005694;chromosome;1.52013229276455e-31!GO:0005830;cytosolic ribosome (sensu Eukaryota);3.71070439476879e-31!GO:0006281;DNA repair;3.93218884993676e-31!GO:0044445;cytosolic part;1.97019188306538e-29!GO:0000278;mitotic cell cycle;2.53246008706389e-29!GO:0006886;intracellular protein transport;4.7476456849887e-29!GO:0016462;pyrophosphatase activity;5.24364150945908e-29!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;7.50507564120531e-29!GO:0016817;hydrolase activity, acting on acid anhydrides;1.02537927733044e-28!GO:0044451;nucleoplasm part;1.21483979575308e-28!GO:0017111;nucleoside-triphosphatase activity;2.49588285928225e-28!GO:0016070;RNA metabolic process;1.77219446756956e-27!GO:0044427;chromosomal part;1.95280462815115e-27!GO:0051276;chromosome organization and biogenesis;2.79504189325942e-27!GO:0005730;nucleolus;1.88200865151052e-26!GO:0032553;ribonucleotide binding;5.42051468129571e-26!GO:0032555;purine ribonucleotide binding;5.42051468129571e-26!GO:0017076;purine nucleotide binding;7.59678386130552e-26!GO:0022403;cell cycle phase;2.39684846017265e-25!GO:0031980;mitochondrial lumen;2.70485312273945e-25!GO:0005759;mitochondrial matrix;2.70485312273945e-25!GO:0051649;establishment of cellular localization;9.63805142980469e-25!GO:0000087;M phase of mitotic cell cycle;1.64482115077733e-24!GO:0044455;mitochondrial membrane part;2.78103346483339e-24!GO:0006260;DNA replication;3.07233714338082e-24!GO:0007067;mitosis;3.95117195698232e-24!GO:0051641;cellular localization;4.08852120585083e-24!GO:0009719;response to endogenous stimulus;8.59093330178411e-24!GO:0022618;protein-RNA complex assembly;1.81484279182575e-23!GO:0005524;ATP binding;2.34813757352455e-23!GO:0015935;small ribosomal subunit;2.41139198558098e-23!GO:0051301;cell division;4.27295481208665e-23!GO:0032559;adenyl ribonucleotide binding;4.63307155862944e-23!GO:0006119;oxidative phosphorylation;5.35383951333493e-23!GO:0030554;adenyl nucleotide binding;1.12673259393586e-22!GO:0015934;large ribosomal subunit;3.04397426086385e-22!GO:0000279;M phase;3.60786641470025e-22!GO:0016874;ligase activity;2.42764546727719e-21!GO:0044265;cellular macromolecule catabolic process;4.50979108128609e-21!GO:0016887;ATPase activity;1.92922528514074e-20!GO:0042254;ribosome biogenesis and assembly;1.98213222740288e-20!GO:0006325;establishment and/or maintenance of chromatin architecture;2.09816200691875e-20!GO:0006323;DNA packaging;1.07282623241826e-19!GO:0042623;ATPase activity, coupled;1.44581672313351e-19!GO:0006512;ubiquitin cycle;4.03170894884532e-19!GO:0006457;protein folding;7.11929929280075e-19!GO:0012505;endomembrane system;2.5284002884806e-18!GO:0005746;mitochondrial respiratory chain;3.82496262092719e-18!GO:0008135;translation factor activity, nucleic acid binding;5.84496488861078e-18!GO:0016604;nuclear body;6.24209908000403e-18!GO:0051186;cofactor metabolic process;1.09780059438473e-17!GO:0009057;macromolecule catabolic process;1.35998504707906e-17!GO:0000398;nuclear mRNA splicing, via spliceosome;3.12459851795556e-17!GO:0000375;RNA splicing, via transesterification reactions;3.12459851795556e-17!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;3.12459851795556e-17!GO:0044248;cellular catabolic process;3.65070173592562e-17!GO:0005761;mitochondrial ribosome;4.90738092886323e-17!GO:0000313;organellar ribosome;4.90738092886323e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;6.78219310129669e-17!GO:0004386;helicase activity;1.20202644714808e-16!GO:0000502;proteasome complex (sensu Eukaryota);1.22692717251534e-16!GO:0043285;biopolymer catabolic process;1.37945801343911e-16!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.41705822659151e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;3.06854058879713e-16!GO:0019941;modification-dependent protein catabolic process;3.13157897639489e-16!GO:0043632;modification-dependent macromolecule catabolic process;3.13157897639489e-16!GO:0065004;protein-DNA complex assembly;5.36082120230283e-16!GO:0050136;NADH dehydrogenase (quinone) activity;5.36918029241548e-16!GO:0003954;NADH dehydrogenase activity;5.36918029241548e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;5.36918029241548e-16!GO:0044257;cellular protein catabolic process;5.48013597034545e-16!GO:0006333;chromatin assembly or disassembly;7.02271397372645e-16!GO:0006511;ubiquitin-dependent protein catabolic process;7.02271397372645e-16!GO:0044453;nuclear membrane part;7.0402443493266e-16!GO:0005635;nuclear envelope;8.0361776124144e-16!GO:0006399;tRNA metabolic process;2.48735942732195e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.75253213251386e-15!GO:0003743;translation initiation factor activity;3.38659040708709e-15!GO:0051726;regulation of cell cycle;8.99279781115498e-15!GO:0006413;translational initiation;9.23730767628649e-15!GO:0000074;regulation of progression through cell cycle;1.34193457362904e-14!GO:0006605;protein targeting;1.38437906422331e-14!GO:0031965;nuclear membrane;2.2605145170227e-14!GO:0016607;nuclear speck;2.91085623955826e-14!GO:0006364;rRNA processing;3.39225786234961e-14!GO:0008026;ATP-dependent helicase activity;3.48701451657208e-14!GO:0000785;chromatin;3.60632261018671e-14!GO:0042775;organelle ATP synthesis coupled electron transport;3.70436406965063e-14!GO:0042773;ATP synthesis coupled electron transport;3.70436406965063e-14!GO:0050657;nucleic acid transport;3.85315474375754e-14!GO:0051236;establishment of RNA localization;3.85315474375754e-14!GO:0050658;RNA transport;3.85315474375754e-14!GO:0030964;NADH dehydrogenase complex (quinone);4.86978818986156e-14!GO:0045271;respiratory chain complex I;4.86978818986156e-14!GO:0005747;mitochondrial respiratory chain complex I;4.86978818986156e-14!GO:0048770;pigment granule;5.42959635253553e-14!GO:0042470;melanosome;5.42959635253553e-14!GO:0008134;transcription factor binding;7.05718263815207e-14!GO:0006732;coenzyme metabolic process;7.93553929455828e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;9.284068952154e-14!GO:0016072;rRNA metabolic process;9.7838591431446e-14!GO:0006403;RNA localization;1.04347470790389e-13!GO:0005643;nuclear pore;1.2332269900604e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.46261845493469e-13!GO:0043412;biopolymer modification;1.64754989075959e-13!GO:0051082;unfolded protein binding;3.26162183126951e-13!GO:0006261;DNA-dependent DNA replication;7.20590502166269e-13!GO:0006446;regulation of translational initiation;8.89147518135534e-13!GO:0006334;nucleosome assembly;9.78650417519145e-13!GO:0030163;protein catabolic process;1.0695840085174e-12!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.27830830346743e-12!GO:0031497;chromatin assembly;3.47712629027031e-12!GO:0065002;intracellular protein transport across a membrane;3.58902108851929e-12!GO:0015630;microtubule cytoskeleton;4.00701078928764e-12!GO:0051028;mRNA transport;4.17635374121548e-12!GO:0016568;chromatin modification;5.70903593382308e-12!GO:0046930;pore complex;6.07789120767462e-12!GO:0003697;single-stranded DNA binding;7.42440228172268e-12!GO:0006913;nucleocytoplasmic transport;1.03208753457773e-11!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.20419364464528e-11!GO:0004812;aminoacyl-tRNA ligase activity;1.20419364464528e-11!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.20419364464528e-11!GO:0043566;structure-specific DNA binding;1.59754109523759e-11!GO:0051169;nuclear transport;2.1806579980718e-11!GO:0044432;endoplasmic reticulum part;2.41606295383502e-11!GO:0000775;chromosome, pericentric region;2.45175799110193e-11!GO:0048193;Golgi vesicle transport;2.94893607161194e-11!GO:0043038;amino acid activation;4.34147405538453e-11!GO:0006418;tRNA aminoacylation for protein translation;4.34147405538453e-11!GO:0043039;tRNA aminoacylation;4.34147405538453e-11!GO:0006464;protein modification process;5.86104998617487e-11!GO:0016779;nucleotidyltransferase activity;8.89265550658285e-11!GO:0008565;protein transporter activity;9.36421411057825e-11!GO:0005819;spindle;1.28423780036357e-10!GO:0030532;small nuclear ribonucleoprotein complex;1.289478015786e-10!GO:0016787;hydrolase activity;1.41333476703144e-10!GO:0051188;cofactor biosynthetic process;1.58273912678094e-10!GO:0003712;transcription cofactor activity;1.90957907951921e-10!GO:0006163;purine nucleotide metabolic process;2.53437663353847e-10!GO:0009259;ribonucleotide metabolic process;3.35274798098391e-10!GO:0005783;endoplasmic reticulum;6.65370198744403e-10!GO:0009056;catabolic process;6.6940206262711e-10!GO:0005813;centrosome;1.0002973000949e-09!GO:0006164;purine nucleotide biosynthetic process;1.10554724075997e-09!GO:0005815;microtubule organizing center;1.79386620455386e-09!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.35439905038631e-09!GO:0043687;post-translational protein modification;2.77778601866302e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;3.01490148950695e-09!GO:0016740;transferase activity;3.15812390270811e-09!GO:0009260;ribonucleotide biosynthetic process;3.34226054368417e-09!GO:0009150;purine ribonucleotide metabolic process;3.78818887192719e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;4.55591259150694e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;4.885174315532e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;8.57122265576929e-09!GO:0007005;mitochondrion organization and biogenesis;9.72111595903931e-09!GO:0009055;electron carrier activity;1.01115901052946e-08!GO:0017038;protein import;1.09683980352086e-08!GO:0005789;endoplasmic reticulum membrane;1.10786294681256e-08!GO:0016192;vesicle-mediated transport;1.30612803722235e-08!GO:0008639;small protein conjugating enzyme activity;1.49149851774747e-08!GO:0009152;purine ribonucleotide biosynthetic process;1.69931665891363e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.04858321012237e-08!GO:0015078;hydrogen ion transmembrane transporter activity;2.20768485535415e-08!GO:0009060;aerobic respiration;2.3312974661169e-08!GO:0012501;programmed cell death;2.67560351989035e-08!GO:0006915;apoptosis;3.13044127843012e-08!GO:0006366;transcription from RNA polymerase II promoter;3.37643719283252e-08!GO:0015986;ATP synthesis coupled proton transport;3.39103146563549e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;3.39103146563549e-08!GO:0003899;DNA-directed RNA polymerase activity;4.05248099695974e-08!GO:0004842;ubiquitin-protein ligase activity;4.12393426122456e-08!GO:0009141;nucleoside triphosphate metabolic process;4.19267676660948e-08!GO:0009199;ribonucleoside triphosphate metabolic process;4.34326510967446e-08!GO:0000245;spliceosome assembly;4.79898738647751e-08!GO:0007051;spindle organization and biogenesis;4.82465943146406e-08!GO:0032446;protein modification by small protein conjugation;5.226291923853e-08!GO:0019829;cation-transporting ATPase activity;5.60730720954842e-08!GO:0006461;protein complex assembly;6.31420764044278e-08!GO:0019787;small conjugating protein ligase activity;7.26981298393717e-08!GO:0005657;replication fork;7.47383312530676e-08!GO:0051329;interphase of mitotic cell cycle;8.00581767023551e-08!GO:0005794;Golgi apparatus;8.58502471522317e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;9.37286520710196e-08!GO:0009144;purine nucleoside triphosphate metabolic process;9.37286520710196e-08!GO:0009142;nucleoside triphosphate biosynthetic process;9.80864763948197e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;9.80864763948197e-08!GO:0000075;cell cycle checkpoint;1.10345509258434e-07!GO:0051325;interphase;1.10902238508143e-07!GO:0016567;protein ubiquitination;1.31121932554578e-07!GO:0046034;ATP metabolic process;1.36869138312234e-07!GO:0008094;DNA-dependent ATPase activity;1.51321003554126e-07!GO:0016881;acid-amino acid ligase activity;1.53951085541387e-07!GO:0009108;coenzyme biosynthetic process;1.58491558466784e-07!GO:0008219;cell death;1.90741197150853e-07!GO:0016265;death;1.90741197150853e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.17269551481621e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.17269551481621e-07!GO:0006084;acetyl-CoA metabolic process;2.17269551481621e-07!GO:0045333;cellular respiration;2.25795826253978e-07!GO:0006754;ATP biosynthetic process;2.28134956972123e-07!GO:0006753;nucleoside phosphate metabolic process;2.28134956972123e-07!GO:0006099;tricarboxylic acid cycle;2.69227102485375e-07!GO:0046356;acetyl-CoA catabolic process;2.69227102485375e-07!GO:0009117;nucleotide metabolic process;2.85214811214619e-07!GO:0015077;monovalent inorganic cation transmembrane transporter activity;3.20554866186301e-07!GO:0006302;double-strand break repair;3.68059121311148e-07!GO:0006310;DNA recombination;4.31540255361903e-07!GO:0006752;group transfer coenzyme metabolic process;4.65795967866869e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;4.99949206732536e-07!GO:0045259;proton-transporting ATP synthase complex;5.07948343028421e-07!GO:0003724;RNA helicase activity;5.62784986052529e-07!GO:0016491;oxidoreductase activity;7.91380980061188e-07!GO:0000151;ubiquitin ligase complex;8.06626456215098e-07!GO:0006888;ER to Golgi vesicle-mediated transport;8.6491313062186e-07!GO:0000786;nucleosome;8.65650119042642e-07!GO:0048475;coated membrane;8.89089964481838e-07!GO:0030117;membrane coat;8.89089964481838e-07!GO:0005839;proteasome core complex (sensu Eukaryota);9.42749456431512e-07!GO:0006091;generation of precursor metabolites and energy;1.23374319003448e-06!GO:0003684;damaged DNA binding;1.23374319003448e-06!GO:0030120;vesicle coat;1.85222032150037e-06!GO:0030662;coated vesicle membrane;1.85222032150037e-06!GO:0051246;regulation of protein metabolic process;1.91123494021222e-06!GO:0005667;transcription factor complex;2.11595531379919e-06!GO:0044452;nucleolar part;2.14909931574995e-06!GO:0016469;proton-transporting two-sector ATPase complex;2.44231597395378e-06!GO:0009109;coenzyme catabolic process;2.79974518545922e-06!GO:0000776;kinetochore;2.84013969451716e-06!GO:0005762;mitochondrial large ribosomal subunit;3.10326758393565e-06!GO:0000315;organellar large ribosomal subunit;3.10326758393565e-06!GO:0003690;double-stranded DNA binding;3.33573042428625e-06!GO:0016741;transferase activity, transferring one-carbon groups;3.3460881082197e-06!GO:0004298;threonine endopeptidase activity;3.77476367561129e-06!GO:0045786;negative regulation of progression through cell cycle;4.05515058117673e-06!GO:0008168;methyltransferase activity;4.23488876260177e-06!GO:0005768;endosome;5.12405015499195e-06!GO:0003924;GTPase activity;5.47470065805158e-06!GO:0003713;transcription coactivator activity;6.72169243290736e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;6.7371214618275e-06!GO:0004518;nuclease activity;6.96039296346102e-06!GO:0051427;hormone receptor binding;7.69037856841876e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;8.93115765873221e-06!GO:0015399;primary active transmembrane transporter activity;8.93115765873221e-06!GO:0000314;organellar small ribosomal subunit;8.97341147207099e-06!GO:0005763;mitochondrial small ribosomal subunit;8.97341147207099e-06!GO:0008033;tRNA processing;1.02435582891666e-05!GO:0051187;cofactor catabolic process;1.03244282583444e-05!GO:0051168;nuclear export;1.03857128654679e-05!GO:0051170;nuclear import;1.1147288673385e-05!GO:0019843;rRNA binding;1.50394760706633e-05!GO:0004527;exonuclease activity;1.52628074292254e-05!GO:0051052;regulation of DNA metabolic process;1.53552633035498e-05!GO:0035257;nuclear hormone receptor binding;1.81891985027353e-05!GO:0016853;isomerase activity;2.22313191584086e-05!GO:0007059;chromosome segregation;2.23435718513619e-05!GO:0006383;transcription from RNA polymerase III promoter;2.4076123690019e-05!GO:0006613;cotranslational protein targeting to membrane;2.41993703972288e-05!GO:0006793;phosphorus metabolic process;2.55716621204578e-05!GO:0006796;phosphate metabolic process;2.55716621204578e-05!GO:0003678;DNA helicase activity;2.6560697959966e-05!GO:0043021;ribonucleoprotein binding;2.79533024988375e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;3.08945083814835e-05!GO:0006606;protein import into nucleus;3.12035619540393e-05!GO:0008186;RNA-dependent ATPase activity;3.21716979835402e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;3.47487467536243e-05!GO:0019222;regulation of metabolic process;3.67675020782282e-05!GO:0006402;mRNA catabolic process;3.81327545403005e-05!GO:0003729;mRNA binding;3.81327545403005e-05!GO:0006352;transcription initiation;4.17417159473705e-05!GO:0043623;cellular protein complex assembly;4.23176576593306e-05!GO:0016563;transcription activator activity;4.3981538997572e-05!GO:0042981;regulation of apoptosis;4.76673387793824e-05!GO:0005525;GTP binding;4.82138657447197e-05!GO:0016363;nuclear matrix;4.97508277570059e-05!GO:0044440;endosomal part;5.69422793928837e-05!GO:0010008;endosome membrane;5.69422793928837e-05!GO:0043067;regulation of programmed cell death;5.77923051860742e-05!GO:0043069;negative regulation of programmed cell death;5.77923051860742e-05!GO:0006916;anti-apoptosis;5.97573060884895e-05!GO:0006401;RNA catabolic process;6.11867122287721e-05!GO:0003682;chromatin binding;6.4461824392225e-05!GO:0006839;mitochondrial transport;6.57732340680077e-05!GO:0005770;late endosome;7.03834223774455e-05!GO:0045454;cell redox homeostasis;7.23442223704531e-05!GO:0006818;hydrogen transport;7.49335990286297e-05!GO:0043066;negative regulation of apoptosis;7.91935836801964e-05!GO:0043681;protein import into mitochondrion;8.02488115837196e-05!GO:0006626;protein targeting to mitochondrion;8.03279244799211e-05!GO:0007093;mitotic cell cycle checkpoint;8.17207257519432e-05!GO:0032508;DNA duplex unwinding;8.44227547657677e-05!GO:0032392;DNA geometric change;8.44227547657677e-05!GO:0008654;phospholipid biosynthetic process;8.65263137727904e-05!GO:0015992;proton transport;9.09497368304609e-05!GO:0005798;Golgi-associated vesicle;9.27024323277114e-05!GO:0022890;inorganic cation transmembrane transporter activity;9.42744682208827e-05!GO:0004004;ATP-dependent RNA helicase activity;0.000101522323041627!GO:0005793;ER-Golgi intermediate compartment;0.000102491957614225!GO:0009165;nucleotide biosynthetic process;0.000102876501530689!GO:0007088;regulation of mitosis;0.00010685980712195!GO:0006284;base-excision repair;0.00010829263494507!GO:0046483;heterocycle metabolic process;0.000108474598131474!GO:0005874;microtubule;0.000116256021904152!GO:0043492;ATPase activity, coupled to movement of substances;0.000121104877442034!GO:0019752;carboxylic acid metabolic process;0.000126334939603437!GO:0031072;heat shock protein binding;0.000128744059528795!GO:0031252;leading edge;0.000135634074178027!GO:0006414;translational elongation;0.000141421859847346!GO:0006082;organic acid metabolic process;0.000145975066749362!GO:0006268;DNA unwinding during replication;0.000151615375282644!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000163234432738981!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000163647138535694!GO:0006405;RNA export from nucleus;0.000165122759263661!GO:0007017;microtubule-based process;0.000165466037597018!GO:0030880;RNA polymerase complex;0.000179799637231072!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000205666354265206!GO:0007052;mitotic spindle organization and biogenesis;0.000214622735235927!GO:0031988;membrane-bound vesicle;0.000250576359394003!GO:0006270;DNA replication initiation;0.000290647332559787!GO:0019899;enzyme binding;0.000307914177859039!GO:0016310;phosphorylation;0.000308384439904567!GO:0016859;cis-trans isomerase activity;0.000341558780627434!GO:0050794;regulation of cellular process;0.000347275260493724!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000361751571684076!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000364061236564337!GO:0031982;vesicle;0.00037500902740724!GO:0006289;nucleotide-excision repair;0.00037723863797899!GO:0000922;spindle pole;0.000391428368517934!GO:0000049;tRNA binding;0.000414794858635792!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.000454904920148394!GO:0005684;U2-dependent spliceosome;0.000473792703420378!GO:0006612;protein targeting to membrane;0.000473792703420378!GO:0044431;Golgi apparatus part;0.000474279021727116!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000474279021727116!GO:0000428;DNA-directed RNA polymerase complex;0.000474279021727116!GO:0006520;amino acid metabolic process;0.000478878498466858!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.000479985479898015!GO:0031324;negative regulation of cellular metabolic process;0.00051955433154799!GO:0000819;sister chromatid segregation;0.00053129846047153!GO:0050662;coenzyme binding;0.000541973551648099!GO:0016023;cytoplasmic membrane-bound vesicle;0.00056767741650717!GO:0032561;guanyl ribonucleotide binding;0.000569255940925976!GO:0019001;guanyl nucleotide binding;0.000569255940925976!GO:0031968;organelle outer membrane;0.000590702636429899!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000590702636429899!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000590702636429899!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000606357901164565!GO:0000059;protein import into nucleus, docking;0.000640361613202757!GO:0019867;outer membrane;0.000647340412579218!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00066685691390223!GO:0005885;Arp2/3 protein complex;0.000672140431668118!GO:0006950;response to stress;0.000684302791855901!GO:0032200;telomere organization and biogenesis;0.000684302791855901!GO:0000723;telomere maintenance;0.000684302791855901!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.000728206579418148!GO:0051252;regulation of RNA metabolic process;0.000751950429576455!GO:0048523;negative regulation of cellular process;0.000789815128278232!GO:0009892;negative regulation of metabolic process;0.00080928321828391!GO:0000070;mitotic sister chromatid segregation;0.000839134819169139!GO:0048037;cofactor binding;0.000848706022590679!GO:0044262;cellular carbohydrate metabolic process;0.000862219942672101!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000862219942672101!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000862219942672101!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000862219942672101!GO:0031410;cytoplasmic vesicle;0.000884647978130152!GO:0051920;peroxiredoxin activity;0.00089465965093007!GO:0030658;transport vesicle membrane;0.000911321694690349!GO:0005788;endoplasmic reticulum lumen;0.000920803780424774!GO:0005637;nuclear inner membrane;0.000984934200996897!GO:0005048;signal sequence binding;0.00101084784963987!GO:0005741;mitochondrial outer membrane;0.00107038055948283!GO:0007006;mitochondrial membrane organization and biogenesis;0.00109029524802973!GO:0000725;recombinational repair;0.00109029524802973!GO:0000724;double-strand break repair via homologous recombination;0.00109029524802973!GO:0032259;methylation;0.00109303347584424!GO:0006779;porphyrin biosynthetic process;0.00109303347584424!GO:0033014;tetrapyrrole biosynthetic process;0.00109303347584424!GO:0000228;nuclear chromosome;0.00110339351086705!GO:0006118;electron transport;0.00112341155817476!GO:0031323;regulation of cellular metabolic process;0.00119759892753613!GO:0006730;one-carbon compound metabolic process;0.00125023323289852!GO:0043596;nuclear replication fork;0.00126734620963206!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00126734620963206!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00126734620963206!GO:0005769;early endosome;0.00128083271576599!GO:0043414;biopolymer methylation;0.00143068323120287!GO:0005758;mitochondrial intermembrane space;0.00147005750330073!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00159626067965415!GO:0015980;energy derivation by oxidation of organic compounds;0.0017116804560731!GO:0005876;spindle microtubule;0.00171697691469407!GO:0006007;glucose catabolic process;0.00173034294179973!GO:0007010;cytoskeleton organization and biogenesis;0.00173865416777493!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.00173865416777493!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00175124044249318!GO:0006275;regulation of DNA replication;0.0017810170438033!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00183228590801077!GO:0030118;clathrin coat;0.00185197293836505!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00191820124347658!GO:0015002;heme-copper terminal oxidase activity;0.00191820124347658!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00191820124347658!GO:0004129;cytochrome-c oxidase activity;0.00191820124347658!GO:0000287;magnesium ion binding;0.00193363295171779!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00194252466556188!GO:0003714;transcription corepressor activity;0.0020066765583264!GO:0006350;transcription;0.00205674852865149!GO:0004003;ATP-dependent DNA helicase activity;0.00206070536497888!GO:0048500;signal recognition particle;0.00215582496671725!GO:0000082;G1/S transition of mitotic cell cycle;0.002223834196775!GO:0015631;tubulin binding;0.00224206934317733!GO:0030660;Golgi-associated vesicle membrane;0.0023461946454624!GO:0016564;transcription repressor activity;0.00234629937187431!GO:0004674;protein serine/threonine kinase activity;0.00247094808515635!GO:0051087;chaperone binding;0.00255825204677391!GO:0009451;RNA modification;0.00257917300293826!GO:0051053;negative regulation of DNA metabolic process;0.00261869434462778!GO:0031970;organelle envelope lumen;0.00269491560886855!GO:0046474;glycerophospholipid biosynthetic process;0.002723305541902!GO:0000910;cytokinesis;0.0027339972243122!GO:0006778;porphyrin metabolic process;0.00291675648215932!GO:0033013;tetrapyrrole metabolic process;0.00291675648215932!GO:0000339;RNA cap binding;0.00292563363931151!GO:0051540;metal cluster binding;0.00295779827082587!GO:0051536;iron-sulfur cluster binding;0.00295779827082587!GO:0016251;general RNA polymerase II transcription factor activity;0.00295838342578467!GO:0003711;transcription elongation regulator activity;0.0030426405123221!GO:0006611;protein export from nucleus;0.00306790482809428!GO:0000781;chromosome, telomeric region;0.00309701944704495!GO:0047485;protein N-terminus binding;0.0031754521162296!GO:0006338;chromatin remodeling;0.00324168957828093!GO:0044450;microtubule organizing center part;0.00330260275852385!GO:0030176;integral to endoplasmic reticulum membrane;0.00331651184095838!GO:0016272;prefoldin complex;0.00336290735364478!GO:0048471;perinuclear region of cytoplasm;0.0034087917088688!GO:0048519;negative regulation of biological process;0.00345805122381936!GO:0008250;oligosaccharyl transferase complex;0.0034820128478578!GO:0008312;7S RNA binding;0.00348872059083843!GO:0031570;DNA integrity checkpoint;0.00351166118955554!GO:0009112;nucleobase metabolic process;0.00351262598143752!GO:0008139;nuclear localization sequence binding;0.00351262598143752!GO:0051287;NAD binding;0.00368373964245736!GO:0030867;rough endoplasmic reticulum membrane;0.00368373964245736!GO:0043284;biopolymer biosynthetic process;0.00368373964245736!GO:0051539;4 iron, 4 sulfur cluster binding;0.00369733766332223!GO:0008408;3'-5' exonuclease activity;0.00375763157892401!GO:0032984;macromolecular complex disassembly;0.00381021363004299!GO:0006595;polyamine metabolic process;0.00392932769263412!GO:0004576;oligosaccharyl transferase activity;0.00402035807358109!GO:0043601;nuclear replisome;0.00408485356101628!GO:0030894;replisome;0.00408485356101628!GO:0006144;purine base metabolic process;0.00408870184750319!GO:0001726;ruffle;0.00429942853662062!GO:0035258;steroid hormone receptor binding;0.0043578859910885!GO:0007050;cell cycle arrest;0.00438297987258223!GO:0003677;DNA binding;0.00446474487822189!GO:0000139;Golgi membrane;0.00456501185592423!GO:0031124;mRNA 3'-end processing;0.00460587583719975!GO:0030119;AP-type membrane coat adaptor complex;0.0047565765843229!GO:0043488;regulation of mRNA stability;0.00477016134201226!GO:0043487;regulation of RNA stability;0.00477016134201226!GO:0042770;DNA damage response, signal transduction;0.00489811340350496!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00493771130391246!GO:0042393;histone binding;0.00500451541261028!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0050528900629992!GO:0046489;phosphoinositide biosynthetic process;0.00508359136684003!GO:0006783;heme biosynthetic process;0.00517408288347819!GO:0000178;exosome (RNase complex);0.0052238350078116!GO:0006740;NADPH regeneration;0.00532303337953692!GO:0006098;pentose-phosphate shunt;0.00532303337953692!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00547007043566342!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00547007043566342!GO:0045047;protein targeting to ER;0.00547007043566342!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00556190257036763!GO:0005669;transcription factor TFIID complex;0.00572731500103249!GO:0022411;cellular component disassembly;0.00607292541969301!GO:0008022;protein C-terminus binding;0.00607321722870798!GO:0045045;secretory pathway;0.00621487928398443!GO:0051348;negative regulation of transferase activity;0.00628808916043899!GO:0000726;non-recombinational repair;0.00629556904089768!GO:0016584;nucleosome positioning;0.00629714278717977!GO:0006891;intra-Golgi vesicle-mediated transport;0.00638069160451761!GO:0030131;clathrin adaptor complex;0.00639443714703429!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.00647489441348363!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00656884172475112!GO:0030663;COPI coated vesicle membrane;0.00670534370051648!GO:0030126;COPI vesicle coat;0.00670534370051648!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.00676472854960612!GO:0043241;protein complex disassembly;0.00679002547536515!GO:0033673;negative regulation of kinase activity;0.0068005215419363!GO:0006469;negative regulation of protein kinase activity;0.0068005215419363!GO:0006519;amino acid and derivative metabolic process;0.00708510183107622!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00733328568126854!GO:0030134;ER to Golgi transport vesicle;0.00742765115121677!GO:0005996;monosaccharide metabolic process;0.00755462042764707!GO:0043624;cellular protein complex disassembly;0.00763145996800599!GO:0019318;hexose metabolic process;0.00820056174881005!GO:0009303;rRNA transcription;0.00824727560230279!GO:0046365;monosaccharide catabolic process;0.00828839354883382!GO:0006497;protein amino acid lipidation;0.00832500397626396!GO:0004532;exoribonuclease activity;0.00843517187997308!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00843517187997308!GO:0043022;ribosome binding;0.0084452718720751!GO:0009081;branched chain family amino acid metabolic process;0.00868352463933083!GO:0005832;chaperonin-containing T-complex;0.0093227922397763!GO:0051789;response to protein stimulus;0.00936092808848488!GO:0006986;response to unfolded protein;0.00936092808848488!GO:0046966;thyroid hormone receptor binding;0.00940019778427169!GO:0008610;lipid biosynthetic process;0.00981329076262043!GO:0042158;lipoprotein biosynthetic process;0.00984565364363683!GO:0022406;membrane docking;0.0101436378383722!GO:0048278;vesicle docking;0.0101436378383722!GO:0008156;negative regulation of DNA replication;0.0102494680212816!GO:0003725;double-stranded RNA binding;0.0103039249647628!GO:0019372;lipoxygenase pathway;0.0103042833619364!GO:0000792;heterochromatin;0.0103144965371119!GO:0030127;COPII vesicle coat;0.0103144965371119!GO:0012507;ER to Golgi transport vesicle membrane;0.0103144965371119!GO:0006406;mRNA export from nucleus;0.0103144965371119!GO:0042802;identical protein binding;0.0103752258235658!GO:0010468;regulation of gene expression;0.0105563250680093!GO:0046164;alcohol catabolic process;0.0106135259747677!GO:0046467;membrane lipid biosynthetic process;0.0106686126662677!GO:0006417;regulation of translation;0.0106686126662677!GO:0030137;COPI-coated vesicle;0.0107720407984781!GO:0006506;GPI anchor biosynthetic process;0.0109268037386993!GO:0051297;centrosome organization and biogenesis;0.0109533961206127!GO:0031023;microtubule organizing center organization and biogenesis;0.0109533961206127!GO:0030384;phosphoinositide metabolic process;0.0109533961206127!GO:0000096;sulfur amino acid metabolic process;0.0109748954137979!GO:0031123;RNA 3'-end processing;0.0111612455251221!GO:0048487;beta-tubulin binding;0.0113137451621429!GO:0043407;negative regulation of MAP kinase activity;0.0116301708700788!GO:0008276;protein methyltransferase activity;0.0116421006032999!GO:0030508;thiol-disulfide exchange intermediate activity;0.0117176264462961!GO:0007004;telomere maintenance via telomerase;0.0117462347095838!GO:0006220;pyrimidine nucleotide metabolic process;0.0119382727735513!GO:0006376;mRNA splice site selection;0.011976790873452!GO:0000389;nuclear mRNA 3'-splice site recognition;0.011976790873452!GO:0006400;tRNA modification;0.011976790873452!GO:0035267;NuA4 histone acetyltransferase complex;0.0122404442318701!GO:0050178;phenylpyruvate tautomerase activity;0.0122737643752524!GO:0042168;heme metabolic process;0.01256385324617!GO:0000209;protein polyubiquitination;0.0126039299315423!GO:0019320;hexose catabolic process;0.0129842816816743!GO:0040029;regulation of gene expression, epigenetic;0.013123006713548!GO:0016407;acetyltransferase activity;0.013276157381436!GO:0006368;RNA elongation from RNA polymerase II promoter;0.013295305239086!GO:0031577;spindle checkpoint;0.0133981946675909!GO:0016126;sterol biosynthetic process;0.0134274612491555!GO:0043189;H4/H2A histone acetyltransferase complex;0.0134877704389512!GO:0005663;DNA replication factor C complex;0.0136445442612201!GO:0004523;ribonuclease H activity;0.0143093433643404!GO:0018196;peptidyl-asparagine modification;0.0143279143798406!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0143279143798406!GO:0006505;GPI anchor metabolic process;0.0150923229626771!GO:0006378;mRNA polyadenylation;0.0152298951342814!GO:0006807;nitrogen compound metabolic process;0.0152298951342814!GO:0032774;RNA biosynthetic process;0.015369839259968!GO:0000077;DNA damage checkpoint;0.0154449692451777!GO:0008629;induction of apoptosis by intracellular signals;0.015658817965506!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0156993700928621!GO:0003887;DNA-directed DNA polymerase activity;0.015882292764281!GO:0009308;amine metabolic process;0.0160451648340234!GO:0009066;aspartate family amino acid metabolic process;0.0162293592220018!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0170848789702564!GO:0030521;androgen receptor signaling pathway;0.0174223845955419!GO:0044454;nuclear chromosome part;0.0174682837778766!GO:0030133;transport vesicle;0.0174754353125159!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0181809924656087!GO:0006904;vesicle docking during exocytosis;0.018268368496932!GO:0006695;cholesterol biosynthetic process;0.0182783623971927!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0183825301617784!GO:0006351;transcription, DNA-dependent;0.0191135901061382!GO:0031625;ubiquitin protein ligase binding;0.0193564579093669!GO:0031901;early endosome membrane;0.0194165315326898!GO:0008017;microtubule binding;0.0195035661010432!GO:0016481;negative regulation of transcription;0.0199180426202628!GO:0003746;translation elongation factor activity;0.0200096214085954!GO:0000793;condensed chromosome;0.020161818574139!GO:0000152;nuclear ubiquitin ligase complex;0.0204024062027011!GO:0019783;small conjugating protein-specific protease activity;0.0207311043462243!GO:0046112;nucleobase biosynthetic process;0.0209264768698054!GO:0006278;RNA-dependent DNA replication;0.0209446705380622!GO:0042026;protein refolding;0.0213322749847421!GO:0000123;histone acetyltransferase complex;0.0214733368209127!GO:0006607;NLS-bearing substrate import into nucleus;0.0219474882960532!GO:0016790;thiolester hydrolase activity;0.0221097957544462!GO:0012506;vesicle membrane;0.0221671058558195!GO:0008180;signalosome;0.0222450223186275!GO:0006360;transcription from RNA polymerase I promoter;0.0222892967003705!GO:0006672;ceramide metabolic process;0.0223560067580452!GO:0000080;G1 phase of mitotic cell cycle;0.0225837082051486!GO:0006650;glycerophospholipid metabolic process;0.0233005637014089!GO:0030132;clathrin coat of coated pit;0.0233408853858099!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0234096455629891!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.0236424016048544!GO:0008320;protein transmembrane transporter activity;0.0237111292972118!GO:0031326;regulation of cellular biosynthetic process;0.0237111292972118!GO:0005773;vacuole;0.023857484068267!GO:0005732;small nucleolar ribonucleoprotein complex;0.0239475547663862!GO:0004843;ubiquitin-specific protease activity;0.0243034576867502!GO:0015036;disulfide oxidoreductase activity;0.0245824278434905!GO:0006733;oxidoreduction coenzyme metabolic process;0.0249675337841358!GO:0031902;late endosome membrane;0.0253351331749697!GO:0005869;dynactin complex;0.0254864929810809!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0257984119390384!GO:0045039;protein import into mitochondrial inner membrane;0.0257984119390384!GO:0051656;establishment of organelle localization;0.0259703580533703!GO:0001832;blastocyst growth;0.0259975636875613!GO:0006096;glycolysis;0.0261236107266994!GO:0009083;branched chain family amino acid catabolic process;0.026212540477448!GO:0000118;histone deacetylase complex;0.0263028590518681!GO:0016788;hydrolase activity, acting on ester bonds;0.0264128808767951!GO:0051320;S phase;0.0268951283599652!GO:0030518;steroid hormone receptor signaling pathway;0.0269101780319047!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.027436586312059!GO:0008652;amino acid biosynthetic process;0.0274636329995736!GO:0006979;response to oxidative stress;0.027597143518854!GO:0044275;cellular carbohydrate catabolic process;0.0277214212359725!GO:0008538;proteasome activator activity;0.0277398976219872!GO:0030659;cytoplasmic vesicle membrane;0.0277398976219872!GO:0006892;post-Golgi vesicle-mediated transport;0.0277958658412384!GO:0008632;apoptotic program;0.028276909283169!GO:0000930;gamma-tubulin complex;0.0286249088041951!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0288241327738971!GO:0006301;postreplication repair;0.0290470641130121!GO:0019206;nucleoside kinase activity;0.0290889460565386!GO:0031371;ubiquitin conjugating enzyme complex;0.0291767738439221!GO:0007346;regulation of progression through mitotic cell cycle;0.0291767738439221!GO:0016605;PML body;0.0292575346882097!GO:0006541;glutamine metabolic process;0.0292596964423418!GO:0009067;aspartate family amino acid biosynthetic process;0.0296247158596338!GO:0042769;DNA damage response, detection of DNA damage;0.0300719992742626!GO:0004540;ribonuclease activity;0.0301499263844955!GO:0008637;apoptotic mitochondrial changes;0.030172966863784!GO:0043086;negative regulation of catalytic activity;0.0303611792088957!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0307581059452522!GO:0004177;aminopeptidase activity;0.0309559870413501!GO:0030125;clathrin vesicle coat;0.0319222964292435!GO:0030665;clathrin coated vesicle membrane;0.0319222964292435!GO:0005652;nuclear lamina;0.0327061178251712!GO:0005938;cell cortex;0.0327577525480864!GO:0050789;regulation of biological process;0.0334407304867263!GO:0009262;deoxyribonucleotide metabolic process;0.0335316904215295!GO:0004239;methionyl aminopeptidase activity;0.0335497541971804!GO:0044433;cytoplasmic vesicle part;0.0341677340763469!GO:0004221;ubiquitin thiolesterase activity;0.0348860953923512!GO:0009124;nucleoside monophosphate biosynthetic process;0.0351795409223824!GO:0009123;nucleoside monophosphate metabolic process;0.0351795409223824!GO:0004520;endodeoxyribonuclease activity;0.0358288252839351!GO:0000086;G2/M transition of mitotic cell cycle;0.0359366567393726!GO:0001725;stress fiber;0.0363935343474502!GO:0032432;actin filament bundle;0.0363935343474502!GO:0033116;ER-Golgi intermediate compartment membrane;0.036405201853164!GO:0000175;3'-5'-exoribonuclease activity;0.0367161904664654!GO:0005528;FK506 binding;0.0378463375173056!GO:0005527;macrolide binding;0.0378463375173056!GO:0016197;endosome transport;0.0378468676999069!GO:0006767;water-soluble vitamin metabolic process;0.0380707012164704!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0389611046714214!GO:0009116;nucleoside metabolic process;0.0394249468033762!GO:0007098;centrosome cycle;0.0394927140178915!GO:0030496;midbody;0.0396770413468922!GO:0051318;G1 phase;0.0398626080692131!GO:0030911;TPR domain binding;0.0399989823317183!GO:0030261;chromosome condensation;0.040047199569819!GO:0019104;DNA N-glycosylase activity;0.0408068705480979!GO:0006518;peptide metabolic process;0.0413531345587315!GO:0008213;protein amino acid alkylation;0.0415667355549419!GO:0006479;protein amino acid methylation;0.0415667355549419!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0416534500045722!GO:0010257;NADH dehydrogenase complex assembly;0.0416534500045722!GO:0033108;mitochondrial respiratory chain complex assembly;0.0416534500045722!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.042083354231986!GO:0016835;carbon-oxygen lyase activity;0.0422102185000388!GO:0006303;double-strand break repair via nonhomologous end joining;0.0424494657204779!GO:0030174;regulation of DNA replication initiation;0.0424494657204779!GO:0000323;lytic vacuole;0.0430442395984074!GO:0005764;lysosome;0.0430442395984074!GO:0051045;negative regulation of membrane protein ectodomain proteolysis;0.0433004523246336!GO:0051043;regulation of membrane protein ectodomain proteolysis;0.0433004523246336!GO:0031647;regulation of protein stability;0.0441031520069487!GO:0007040;lysosome organization and biogenesis;0.0441821184337811!GO:0004659;prenyltransferase activity;0.04430507801098!GO:0005784;translocon complex;0.0450523995358335!GO:0032040;small subunit processome;0.0453800041318416!GO:0030218;erythrocyte differentiation;0.0458000706058376!GO:0022884;macromolecule transmembrane transporter activity;0.0458000706058376!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0458000706058376!GO:0033170;DNA-protein loading ATPase activity;0.0458000706058376!GO:0003689;DNA clamp loader activity;0.0458000706058376!GO:0035303;regulation of dephosphorylation;0.0458241456714073!GO:0030036;actin cytoskeleton organization and biogenesis;0.0470221464181479!GO:0005791;rough endoplasmic reticulum;0.0471428217337669!GO:0016791;phosphoric monoester hydrolase activity;0.0471438988965178!GO:0008536;Ran GTPase binding;0.0473019757612385!GO:0008143;poly(A) binding;0.0482489233859723!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.048564200469692!GO:0017134;fibroblast growth factor binding;0.0485746652598336!GO:0030833;regulation of actin filament polymerization;0.0487629465223547!GO:0007021;tubulin folding;0.0487629465223547!GO:0050681;androgen receptor binding;0.0489901204220212!GO:0008234;cysteine-type peptidase activity;0.0496054817631419!GO:0016581;NuRD complex;0.0497834988083854!GO:0007033;vacuole organization and biogenesis;0.0499185948703769 | |||
|sample_id=10835 | |sample_id=10835 | ||
|sample_note= | |sample_note= | ||
Line 75: | Line 99: | ||
|sample_tissue=blood | |sample_tissue=blood | ||
|top_motifs=GATA6:2.92175110642;NR5A1,2:2.58656873144;PPARG:2.3416045645;RXR{A,B,G}_{NR1H2,PPAR}dimers:2.03308540285;ELK1,4_GABP{A,B1}:2.02079309428;E2F1..5:1.82705251336;MYB:1.69098769565;POU3F1..4:1.42931040574;ZNF143:1.12789128869;PAX8:1.11685843724;NRF1:1.08499081552;NFY{A,B,C}:1.05873561453;BREu{core}:1.03930734286;ELF1,2,4:0.869973186403;SOX{8,9,10}:0.833372092464;NFE2:0.819070081919;YY1:0.79910319268;POU2F1..3:0.787711455109;CRX:0.765563709131;HOXA9_MEIS1:0.72814997546;PBX1:0.725488578625;STAT5{A,B}:0.72104631617;CUX2:0.707617690731;ZBTB16:0.630428889973;GFI1:0.49926453252;NKX2-3_NKX2-5:0.473430746478;ARID5B:0.473046957105;ALX1:0.441838724088;RORA:0.432668964408;EN1,2:0.383154115417;NKX2-1,4:0.363744503181;PRRX1,2:0.359843860287;NANOG:0.348486113999;NANOG{mouse}:0.347993597087;AR:0.318004022688;NKX3-2:0.292950098994;PAX2:0.277777155492;HOX{A6,A7,B6,B7}:0.272285226446;POU6F1:0.270817762847;TFAP4:0.247126439018;ZNF148:0.240089141012;HES1:0.231028412523;OCT4_SOX2{dimer}:0.213290501921;ONECUT1,2:0.18680623414;NFE2L2:0.175961823857;PAX6:0.152958084224;AHR_ARNT_ARNT2:0.151851049063;RUNX1..3:0.139062511231;ATF5_CREB3:0.123112018992;HOX{A5,B5}:0.105153058905;HNF4A_NR2F1,2:0.0877713290021;CREB1:0.0709181238953;bHLH_family:0.0489494202225;NR6A1:0.0458649671523;FOXD3:0.0263549850617;IKZF2:0.0159080163857;ESRRA:0.0150456201528;TFDP1:0.00113487906585;HBP1_HMGB_SSRP1_UBTF:-0.00716849902804;TEF:-0.0251031351942;POU1F1:-0.0262068145126;SPI1:-0.032794163893;BACH2:-0.0607781066762;FOSL2:-0.0687367879719;NFE2L1:-0.0966585489871;SPIB:-0.0974201867008;TLX2:-0.103401438895;RBPJ:-0.110488546135;SREBF1,2:-0.116416308372;AIRE:-0.123936875788;MEF2{A,B,C,D}:-0.13160664967;HOX{A4,D4}:-0.150218994225;FOXM1:-0.153676156172;SMAD1..7,9:-0.172616056394;SNAI1..3:-0.189367419718;TOPORS:-0.195441161075;SOX5:-0.201586018529;ETS1,2:-0.204208059022;NFKB1_REL_RELA:-0.215200395813;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.221606538051;LEF1_TCF7_TCF7L1,2:-0.225715906234;MAFB:-0.241523558381;EGR1..3:-0.243884264509;NKX3-1:-0.244310578434;FOXA2:-0.253075593764;SOX17:-0.261860930262;HNF1A:-0.272243662154;CDX1,2,4:-0.282497794183;ZEB1:-0.285397446594;REST:-0.287567653312;FOS_FOS{B,L1}_JUN{B,D}:-0.28924555045;RFX1:-0.300749578298;PITX1..3:-0.316397892828;BPTF:-0.342373817765;PAX3,7:-0.345439362699;NKX6-1,2:-0.366340771283;FOX{F1,F2,J1}:-0.374868175863;VSX1,2:-0.376524815975;FOXQ1:-0.376741950356;NFIX:-0.403509640302;HAND1,2:-0.408062198214;PAX1,9:-0.424829857783;HLF:-0.43043147474;ATF4:-0.43233861133;KLF4:-0.434291619313;EP300:-0.437292360702;ZFP161:-0.454491078044;ADNP_IRX_SIX_ZHX:-0.465347896968;GATA4:-0.466974652131;NHLH1,2:-0.468355510001;NKX2-2,8:-0.469187453059;FOX{I1,J2}:-0.474701961631;EVI1:-0.483415504029;STAT1,3:-0.494837324439;FOXN1:-0.498484933646;GTF2A1,2:-0.504673904989;RFX2..5_RFXANK_RFXAP:-0.514168254346;MYOD1:-0.516899188986;FOXP1:-0.529100121467;NR1H4:-0.536724250334;PAX5:-0.545667953087;UFEwm:-0.546683706438;PRDM1:-0.551184106837;FOXP3:-0.557931005177;NR3C1:-0.565458822729;ZIC1..3:-0.574044705081;IRF1,2:-0.604237161164;TBP:-0.611031835355;GCM1,2:-0.626330826564;IRF7:-0.629653207089;DMAP1_NCOR{1,2}_SMARC:-0.630471227416;ZNF238:-0.635535855398;POU5F1:-0.652324792234;ZNF384:-0.666467535323;PAX4:-0.680341514519;CEBPA,B_DDIT3:-0.68345781834;DBP:-0.744206367134;FOX{D1,D2}:-0.754663571946;HMX1:-0.772011820987;TGIF1:-0.778793417517;RXRA_VDR{dimer}:-0.809095232912;MED-1{core}:-0.830483512607;GTF2I:-0.858418288814;ZBTB6:-0.858457933593;NFIL3:-0.858833703283;TP53:-0.8794951201;SRF:-0.908026079314;SPZ1:-0.911134777386;RREB1:-0.918573853736;NFATC1..3:-0.91891589082;FOXL1:-0.953554157636;ATF2:-0.957043100962;JUN:-0.962114447481;LMO2:-0.963655496294;TBX4,5:-0.966794995633;ATF6:-0.966999803407;STAT2,4,6:-0.976488262896;TEAD1:-0.976610841471;MTF1:-0.981215254442;T:-0.98161255402;IKZF1:-1.01460773841;ESR1:-1.04245771581;MAZ:-1.0476040887;CDC5L:-1.06121262071;PATZ1:-1.07247577631;MYBL2:-1.09565963735;MYFfamily:-1.09699657099;HMGA1,2:-1.13659535039;SOX2:-1.13801775913;LHX3,4:-1.1645328978;RXR{A,B,G}:-1.20928146866;GZF1:-1.21523333666;SP1:-1.24711057647;MZF1:-1.26686396405;XCPE1{core}:-1.27814329804;HIC1:-1.27988052143;XBP1:-1.2851701497;HIF1A:-1.30982488661;TLX1..3_NFIC{dimer}:-1.31102003605;GFI1B:-1.33637790891;ALX4:-1.34250062169;PDX1:-1.35441106775;HSF1,2:-1.35902968527;TFAP2B:-1.45650631907;GLI1..3:-1.51189960417;TAL1_TCF{3,4,12}:-1.57244948821;FOXO1,3,4:-1.59584573288;ZNF423:-1.61609133994;EBF1:-1.62526195005;TFAP2{A,C}:-1.64203934401;MTE{core}:-1.87029774926;TFCP2:-1.88181826841 | |top_motifs=GATA6:2.92175110642;NR5A1,2:2.58656873144;PPARG:2.3416045645;RXR{A,B,G}_{NR1H2,PPAR}dimers:2.03308540285;ELK1,4_GABP{A,B1}:2.02079309428;E2F1..5:1.82705251336;MYB:1.69098769565;POU3F1..4:1.42931040574;ZNF143:1.12789128869;PAX8:1.11685843724;NRF1:1.08499081552;NFY{A,B,C}:1.05873561453;BREu{core}:1.03930734286;ELF1,2,4:0.869973186403;SOX{8,9,10}:0.833372092464;NFE2:0.819070081919;YY1:0.79910319268;POU2F1..3:0.787711455109;CRX:0.765563709131;HOXA9_MEIS1:0.72814997546;PBX1:0.725488578625;STAT5{A,B}:0.72104631617;CUX2:0.707617690731;ZBTB16:0.630428889973;GFI1:0.49926453252;NKX2-3_NKX2-5:0.473430746478;ARID5B:0.473046957105;ALX1:0.441838724088;RORA:0.432668964408;EN1,2:0.383154115417;NKX2-1,4:0.363744503181;PRRX1,2:0.359843860287;NANOG:0.348486113999;NANOG{mouse}:0.347993597087;AR:0.318004022688;NKX3-2:0.292950098994;PAX2:0.277777155492;HOX{A6,A7,B6,B7}:0.272285226446;POU6F1:0.270817762847;TFAP4:0.247126439018;ZNF148:0.240089141012;HES1:0.231028412523;OCT4_SOX2{dimer}:0.213290501921;ONECUT1,2:0.18680623414;NFE2L2:0.175961823857;PAX6:0.152958084224;AHR_ARNT_ARNT2:0.151851049063;RUNX1..3:0.139062511231;ATF5_CREB3:0.123112018992;HOX{A5,B5}:0.105153058905;HNF4A_NR2F1,2:0.0877713290021;CREB1:0.0709181238953;bHLH_family:0.0489494202225;NR6A1:0.0458649671523;FOXD3:0.0263549850617;IKZF2:0.0159080163857;ESRRA:0.0150456201528;TFDP1:0.00113487906585;HBP1_HMGB_SSRP1_UBTF:-0.00716849902804;TEF:-0.0251031351942;POU1F1:-0.0262068145126;SPI1:-0.032794163893;BACH2:-0.0607781066762;FOSL2:-0.0687367879719;NFE2L1:-0.0966585489871;SPIB:-0.0974201867008;TLX2:-0.103401438895;RBPJ:-0.110488546135;SREBF1,2:-0.116416308372;AIRE:-0.123936875788;MEF2{A,B,C,D}:-0.13160664967;HOX{A4,D4}:-0.150218994225;FOXM1:-0.153676156172;SMAD1..7,9:-0.172616056394;SNAI1..3:-0.189367419718;TOPORS:-0.195441161075;SOX5:-0.201586018529;ETS1,2:-0.204208059022;NFKB1_REL_RELA:-0.215200395813;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.221606538051;LEF1_TCF7_TCF7L1,2:-0.225715906234;MAFB:-0.241523558381;EGR1..3:-0.243884264509;NKX3-1:-0.244310578434;FOXA2:-0.253075593764;SOX17:-0.261860930262;HNF1A:-0.272243662154;CDX1,2,4:-0.282497794183;ZEB1:-0.285397446594;REST:-0.287567653312;FOS_FOS{B,L1}_JUN{B,D}:-0.28924555045;RFX1:-0.300749578298;PITX1..3:-0.316397892828;BPTF:-0.342373817765;PAX3,7:-0.345439362699;NKX6-1,2:-0.366340771283;FOX{F1,F2,J1}:-0.374868175863;VSX1,2:-0.376524815975;FOXQ1:-0.376741950356;NFIX:-0.403509640302;HAND1,2:-0.408062198214;PAX1,9:-0.424829857783;HLF:-0.43043147474;ATF4:-0.43233861133;KLF4:-0.434291619313;EP300:-0.437292360702;ZFP161:-0.454491078044;ADNP_IRX_SIX_ZHX:-0.465347896968;GATA4:-0.466974652131;NHLH1,2:-0.468355510001;NKX2-2,8:-0.469187453059;FOX{I1,J2}:-0.474701961631;EVI1:-0.483415504029;STAT1,3:-0.494837324439;FOXN1:-0.498484933646;GTF2A1,2:-0.504673904989;RFX2..5_RFXANK_RFXAP:-0.514168254346;MYOD1:-0.516899188986;FOXP1:-0.529100121467;NR1H4:-0.536724250334;PAX5:-0.545667953087;UFEwm:-0.546683706438;PRDM1:-0.551184106837;FOXP3:-0.557931005177;NR3C1:-0.565458822729;ZIC1..3:-0.574044705081;IRF1,2:-0.604237161164;TBP:-0.611031835355;GCM1,2:-0.626330826564;IRF7:-0.629653207089;DMAP1_NCOR{1,2}_SMARC:-0.630471227416;ZNF238:-0.635535855398;POU5F1:-0.652324792234;ZNF384:-0.666467535323;PAX4:-0.680341514519;CEBPA,B_DDIT3:-0.68345781834;DBP:-0.744206367134;FOX{D1,D2}:-0.754663571946;HMX1:-0.772011820987;TGIF1:-0.778793417517;RXRA_VDR{dimer}:-0.809095232912;MED-1{core}:-0.830483512607;GTF2I:-0.858418288814;ZBTB6:-0.858457933593;NFIL3:-0.858833703283;TP53:-0.8794951201;SRF:-0.908026079314;SPZ1:-0.911134777386;RREB1:-0.918573853736;NFATC1..3:-0.91891589082;FOXL1:-0.953554157636;ATF2:-0.957043100962;JUN:-0.962114447481;LMO2:-0.963655496294;TBX4,5:-0.966794995633;ATF6:-0.966999803407;STAT2,4,6:-0.976488262896;TEAD1:-0.976610841471;MTF1:-0.981215254442;T:-0.98161255402;IKZF1:-1.01460773841;ESR1:-1.04245771581;MAZ:-1.0476040887;CDC5L:-1.06121262071;PATZ1:-1.07247577631;MYBL2:-1.09565963735;MYFfamily:-1.09699657099;HMGA1,2:-1.13659535039;SOX2:-1.13801775913;LHX3,4:-1.1645328978;RXR{A,B,G}:-1.20928146866;GZF1:-1.21523333666;SP1:-1.24711057647;MZF1:-1.26686396405;XCPE1{core}:-1.27814329804;HIC1:-1.27988052143;XBP1:-1.2851701497;HIF1A:-1.30982488661;TLX1..3_NFIC{dimer}:-1.31102003605;GFI1B:-1.33637790891;ALX4:-1.34250062169;PDX1:-1.35441106775;HSF1,2:-1.35902968527;TFAP2B:-1.45650631907;GLI1..3:-1.51189960417;TAL1_TCF{3,4,12}:-1.57244948821;FOXO1,3,4:-1.59584573288;ZNF423:-1.61609133994;EBF1:-1.62526195005;TFAP2{A,C}:-1.64203934401;MTE{core}:-1.87029774926;TFCP2:-1.88181826841 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10835-111D7;search_select_hide=table117:FF:10835-111D7 | |||
}} | }} |
Latest revision as of 15:08, 3 June 2020
Name: | acute myeloid leukemia (FAB M6) cell line:EEB |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13059 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13059
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13059
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0588 |
10 | 10 | 0.0243 |
100 | 100 | 0.518 |
101 | 101 | 0.735 |
102 | 102 | 0.332 |
103 | 103 | 0.584 |
104 | 104 | 0.829 |
105 | 105 | 0.722 |
106 | 106 | 0.0585 |
107 | 107 | 0.0367 |
108 | 108 | 0.405 |
109 | 109 | 0.0322 |
11 | 11 | 0.178 |
110 | 110 | 0.338 |
111 | 111 | 0.123 |
112 | 112 | 0.995 |
113 | 113 | 0.0858 |
114 | 114 | 0.15 |
115 | 115 | 0.452 |
116 | 116 | 0.139 |
117 | 117 | 0.0174 |
118 | 118 | 0.309 |
119 | 119 | 0.352 |
12 | 12 | 0.324 |
120 | 120 | 0.514 |
121 | 121 | 0.769 |
122 | 122 | 0.114 |
123 | 123 | 0.142 |
124 | 124 | 0.389 |
125 | 125 | 0.326 |
126 | 126 | 0.756 |
127 | 127 | 0.24 |
128 | 128 | 0.139 |
129 | 129 | 0.227 |
13 | 13 | 0.0621 |
130 | 130 | 0.17 |
131 | 131 | 0.522 |
132 | 132 | 0.138 |
133 | 133 | 0.958 |
134 | 134 | 0.689 |
135 | 135 | 0.821 |
136 | 136 | 0.0972 |
137 | 137 | 0.23 |
138 | 138 | 0.905 |
139 | 139 | 0.222 |
14 | 14 | 0.922 |
140 | 140 | 0.773 |
141 | 141 | 0.204 |
142 | 142 | 0.878 |
143 | 143 | 0.78 |
144 | 144 | 0.552 |
145 | 145 | 0.807 |
146 | 146 | 0.954 |
147 | 147 | 0.117 |
148 | 148 | 0.26 |
149 | 149 | 0.0632 |
15 | 15 | 0.0374 |
150 | 150 | 0.906 |
151 | 151 | 0.628 |
152 | 152 | 0.0196 |
153 | 153 | 0.499 |
154 | 154 | 0.42 |
155 | 155 | 0.054 |
156 | 156 | 0.119 |
157 | 157 | 0.685 |
158 | 158 | 0.658 |
159 | 159 | 0.141 |
16 | 16 | 0.995 |
160 | 160 | 0.947 |
161 | 161 | 0.122 |
162 | 162 | 0.671 |
163 | 163 | 0.632 |
164 | 164 | 0.85 |
165 | 165 | 0.829 |
166 | 166 | 0.0727 |
167 | 167 | 0.335 |
168 | 168 | 0.216 |
169 | 169 | 0.913 |
17 | 17 | 0.838 |
18 | 18 | 0.966 |
19 | 19 | 0.743 |
2 | 2 | 0.261 |
20 | 20 | 0.221 |
21 | 21 | 0.415 |
22 | 22 | 0.894 |
23 | 23 | 0.0816 |
24 | 24 | 0.0269 |
25 | 25 | 0.0908 |
26 | 26 | 0.0505 |
27 | 27 | 0.588 |
28 | 28 | 0.411 |
29 | 29 | 0.0705 |
3 | 3 | 0.537 |
30 | 30 | 0.0817 |
31 | 31 | 0.626 |
32 | 32 | 0.166 |
33 | 33 | 0.0429 |
34 | 34 | 0.741 |
35 | 35 | 0.273 |
36 | 36 | 0.0214 |
37 | 37 | 0.618 |
38 | 38 | 0.299 |
39 | 39 | 0.116 |
4 | 4 | 0.067 |
40 | 40 | 0.411 |
41 | 41 | 0.924 |
42 | 42 | 0.325 |
43 | 43 | 0.819 |
44 | 44 | 0.514 |
45 | 45 | 0.358 |
46 | 46 | 0.518 |
47 | 47 | 0.0442 |
48 | 48 | 0.267 |
49 | 49 | 0.391 |
5 | 5 | 0.922 |
50 | 50 | 0.375 |
51 | 51 | 0.769 |
52 | 52 | 0.048 |
53 | 53 | 0.923 |
54 | 54 | 0.441 |
55 | 55 | 0.477 |
56 | 56 | 0.658 |
57 | 57 | 0.253 |
58 | 58 | 0.275 |
59 | 59 | 0.811 |
6 | 6 | 0.254 |
60 | 60 | 0.561 |
61 | 61 | 0.242 |
62 | 62 | 0.315 |
63 | 63 | 0.537 |
64 | 64 | 0.622 |
65 | 65 | 0.551 |
66 | 66 | 1.16577e-5 |
67 | 67 | 0.651 |
68 | 68 | 0.501 |
69 | 69 | 0.658 |
7 | 7 | 0.0394 |
70 | 70 | 0.34 |
71 | 71 | 0.222 |
72 | 72 | 0.573 |
73 | 73 | 0.726 |
74 | 74 | 0.701 |
75 | 75 | 0.0086 |
76 | 76 | 0.215 |
77 | 77 | 0.17 |
78 | 78 | 0.0161 |
79 | 79 | 0.0685 |
8 | 8 | 0.422 |
80 | 80 | 0.181 |
81 | 81 | 0.47 |
82 | 82 | 0.77 |
83 | 83 | 0.155 |
84 | 84 | 0.22 |
85 | 85 | 0.0556 |
86 | 86 | 0.605 |
87 | 87 | 0.076 |
88 | 88 | 0.575 |
89 | 89 | 0.467 |
9 | 9 | 0.615 |
90 | 90 | 0.176 |
91 | 91 | 0.15 |
92 | 92 | 0.438 |
93 | 93 | 0.551 |
94 | 94 | 0.902 |
95 | 95 | 0.0255 |
96 | 96 | 0.438 |
97 | 97 | 0.962 |
98 | 98 | 0.146 |
99 | 99 | 0.288 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13059
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101883 acute myeloid leukemia cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0101883 (acute myeloid leukemia cell line sample)
0100740 (myeloid leukemia cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)