FF:11388-118C2: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet=UBERON: | |DRA_sample_Accession=CAGE@SAMD00004845 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |DRA_sample_Accession_RNASeq=sRNA-Seq@SAMD00004845 | ||
|accession_numbers=CAGE;DRX008403;DRR009275;DRZ000700;DRZ002085;DRZ012050;DRZ013435 | |||
|accession_numbers_RNASeq=sRNA-Seq;DRX037061;DRR041427;DRZ007069 | |||
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0000178,UBERON:0004120,UBERON:0000061,UBERON:0000465,UBERON:0000179,UBERON:0000463,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0010317,UBERON:0002390,UBERON:0004535,UBERON:0002193,UBERON:0001009 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000219,CL:0000738,CL:0002087,CL:0000255,CL:0000226,CL:0000080,CL:0000842 | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000135 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!2.35!224.98!PLEK;;chr1:25256756..25256774,-!p1@RUNX3!2.17!268.21!RUNX3;;chr11:47400078..47400106,-!p1@SPI1!2.17!145.36!SPI1;;chr2:157189180..157189290,-!p1@NR4A2!2.05!546.23!NR4A2;;chr16:85932760..85932775,+!p1@IRF8!1.97!92.11!IRF8;;chr12:54778471..54778528,-!p1@ZNF385A!1.93!83.99!ZNF385A;;chr19:54058073..54058088,+!p1@ZNF331!1.91!80.58!ZNF331;;chr19:54041669..54041697,+!p2@ZNF331!1.89!77.38!ZNF331;;chr7:50343634..50343717,+!p2@IKZF1!1.85!69.05!IKZF1;;chr2:192015701..192015743,-!p1@STAT4!1.83!89.44!STAT4;;chr20:50159198..50159299,-!p1@NFATC2!1.79!87.84!NFATC2;;chr17:45810594..45810608,+!p1@TBX21!1.79!61.15!TBX21;;chr5:133451294..133451310,+!p2@TCF7!1.78!58.91!TCF7;;chr9:102584262..102584276,+!p1@NR4A3!1.76!123.16!NR4A3;;chr9:117150254..117150271,-!p1@AKNA!1.69!128.07!AKNA;;chr14:35873947..35873965,-!p1@NFKBIA!1.63!2494.65!NFKBIA;;chr5:133450365..133450444,+!p1@TCF7!1.63!182.82!TCF7;;chr3:63953435..63953499,+!p1@ATXN7!1.63!41.41!ATXN7;;chr6:91006518..91006570,-!p1@BACH2!1.58!82.50!BACH2;;chr11:47400062..47400077,-!p2@SPI1!1.55!34.15!SPI1;;chr11:47399947..47399961,-!p3@SPI1!1.54!33.62!SPI1;;chr6:391743..391759,+!p1@IRF4!1.54!33.62!IRF4;;chr7:50344289..50344323,+!p1@IKZF1!1.54!33.51!IKZF1;;chrY:21906594..21906622,-!p1@KDM5D!1.53!32.98!KDM5D;;chr3:39195075..39195088,-!p1@CSRNP1!1.52!195.42!CSRNP1;;chr2:231090433..231090469,+!p1@SP140!1.52!32.45!SP140;;chr8:123793988..123794016,+!p1@ZHX2!1.50!52.94!ZHX2;;chr4:109087445..109087463,-!p1@LEF1!1.49!29.88!LEF1;;chr19:45971246..45971265,+!p1@FOSB!1.48!523.71!FOSB;;chr15:60884706..60884743,-!p1@RORA!1.48!146.86!RORA;;chr9:102584241..102584261,+!p4@NR4A3!1.47!43.65!NR4A3;;chr6:106546808..106546833,+!p3@PRDM1!1.47!35.86!PRDM1;;chr19:12902289..12902307,+!p1@JUNB!1.46!6111.86!JUNB;;chr2:145277640..145277771,-!p1@ZEB2!1.45!350.39!ZEB2;;chr14:75745523..75745537,+!p1@FOS!1.44!3053.90!FOS;;chr3:101546827..101546847,+!p2@NFKBIZ!1.43!36.39!NFKBIZ;;chr12:72056800..72056834,+!p1@THAP2!1.42!34.15!THAP2;;chrX:106960285..106960299,-!p1@TSC22D3!1.40!616.78!TSC22D3;;chr10:35484053..35484076,+!p1@CREM!1.39!57.21!CREM;;chr9:102584159..102584174,+!p2@NR4A3!1.39!41.62!NR4A3;;chr19:36391434..36391450,-!p1@NFKBID!1.38!44.61!NFKBID;;chr19:16435625..16435682,+!p1@KLF2!1.37!700.77!KLF2;;chr2:61108695..61108753,+!p1@REL!1.37!149.74!REL;;chr14:35872453..35872485,-!p2@NFKBIA!1.37!53.90!NFKBIA;;chr3:71355163..71355209,-!p5@FOXP1!1.37!31.16!FOXP1;;chr19:54041645..54041661,+!p5@ZNF331!1.37!22.52!ZNF331;;chr19:50922187..50922204,+!p1@SPIB!1.36!21.88!SPIB;;chr20:56195474..56195506,-!p1@ZBP1!1.36!21.88!ZBP1;;chrX:106960180..106960197,-!p2@TSC22D3!1.34!77.48!TSC22D3;;chr14:35872962..35873025,-!p3@NFKBIA!1.34!51.98!NFKBIA;;chr12:52445218..52445237,+!p1@NR4A1!1.33!246.75!NR4A1;;chr4:103422499..103422632,+!p1@NFKB1!1.32!402.15!NFKB1;;chr20:39317868..39317884,-!p1@MAFB!1.32!226.69!MAFB;;chr3:18486354..18486377,-!p2@SATB1!1.32!24.65!SATB1;;chr7:115670804..115670825,-!p1@TFEC!1.32!19.96!TFEC;;chr11:47399996..47400014,-!p4@SPI1!1.32!19.85!SPI1;;chr2:68592394..68592405,+!p2@PLEK!1.30!19.10!PLEK;;chr3:39195037..39195069,-!p2@CSRNP1!1.29!111.32!CSRNP1;;chr2:192015750..192015793,-!p2@STAT4!1.29!24.65!STAT4;;chr2:43453734..43453751,-!p1@ZFP36L2!1.27!1837.10!ZFP36L2;;chr3:101568349..101568365,+!p1@NFKBIZ!1.27!893.52!NFKBIZ;;chr5:131826457..131826514,-!p1@IRF1!1.26!657.66!IRF1;;chr6:106534192..106534224,+!p1@PRDM1!1.26!47.92!PRDM1;;chr10:8096631..8096660,+!p1@GATA3!1.24!19.96!GATA3;;chr12:54778351..54778378,-!p6@ZNF385A!1.24!16.22!ZNF385A;;chr2:70142232..70142251,+!p1@MXD1!1.23!89.22!MXD1;;chrX:106960221..106960236,-!p3@TSC22D3!1.22!42.48!TSC22D3;;chr6:91006575..91006602,-!p2@BACH2!1.22!23.27!BACH2;;chr2:61108878..61108891,+!p5@REL!1.22!15.69!REL;;chr2:157189617..157189667,-!p4@NR4A2!1.22!15.58!NR4A2;;chr19:45252008..45252024,+!p2@BCL3!1.21!50.27!BCL3;;chr7:50344251..50344288,+!p3@IKZF1!1.21!15.16!IKZF1;;chr6:12011943..12012015,+!p2@HIVEP1!1.20!47.28!HIVEP1;;chr3:5020939..5020952,+!p2@BHLHE40!1.20!46.00!BHLHE40;;chr9:102584128..102584144,+!p3@NR4A3!1.20!28.28!NR4A3;;chr8:67525443..67525459,-!p2@MYBL1!1.20!22.20!MYBL1;;chr3:71542615..71542644,-!p12@FOXP1!1.20!14.73!FOXP1;;chr10:8096772..8096787,+!p2@GATA3!1.19!17.29!GATA3;;chr2:231090471..231090504,+!p2@SP140!1.19!14.62!SP140;;chrY:2803415..2803468,+!p1@ZFY!1.19!14.62!ZFY;;chr6:106534230..106534254,+!p2@PRDM1!1.18!35.65!PRDM1;;chr8:81397820..81397836,+!p2@ZBTB10!1.18!17.72!ZBTB10;;chr6:106546834..106546850,+!p4@PRDM1!1.18!14.19!PRDM1;;chr9:102584278..102584285,+!p5@NR4A3!1.18!14.09!NR4A3;;chr3:23986824..23986848,+!p2@NR1D2!1.17!76.20!NR1D2;;chr21:36421535..36421610,-!p2@RUNX1!1.17!48.45!RUNX1;;chr14:35872926..35872951,-!p4@NFKBIA!1.17!19.42!NFKBIA;;chr2:61108808..61108821,+!p3@REL!1.17!17.29!REL;;chr13:74707894..74707947,-!p6@KLF12!1.17!15.26!KLF12;;chr11:47400032..47400043,-!p5@SPI1!1.16!13.45!SPI1;;chr4:109090075..109090095,-!p2@LEF1!1.16!13.45!LEF1;;chr2:97202480..97202499,+!p1@ARID5A!1.15!131.92!ARID5A;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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000842;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390 | |||
|ffid_belonging_in_development=CL:0000134 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 34: | Line 44: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Peripheral%2520Blood%2520Mononuclear%2520Cells%252c%2520donor3.CNhs12002.11388-118C2.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Peripheral%2520Blood%2520Mononuclear%2520Cells%252c%2520donor3.CNhs12002.11388-118C2.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Peripheral%2520Blood%2520Mononuclear%2520Cells%252c%2520donor3.CNhs12002.11388-118C2.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Peripheral%2520Blood%2520Mononuclear%2520Cells%252c%2520donor3.CNhs12002.11388-118C2.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Peripheral%2520Blood%2520Mononuclear%2520Cells%252c%2520donor3.CNhs12002.11388-118C2.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11388-118C2 | |id=FF:11388-118C2 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0000135 | ||
|is_obsolete= | |||
|library_id=CNhs12002 | |||
|library_id_phase_based=2:CNhs12002 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11388 | |||
|microRNAs_nonnovel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer/#/human#srna;sample;SRhi10005.ACTTGA.11388 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11388 | |||
|microRNAs_novel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer_novel/#/human#srna;sample;SRhi10005.ACTTGA.11388 | |||
|name=Peripheral Blood Mononuclear Cells, donor3 | |name=Peripheral Blood Mononuclear Cells, donor3 | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
Line 41: | Line 65: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs12002,LSID837,release011,COMPLETED | |profile_hcage=CNhs12002,LSID837,release011,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=SRhi10005,,, | |profile_srnaseq=SRhi10005,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0.00383844486744114,0.337260166188229,0.0603170143018365,0.0809264162802909,0,0.0840237168815831,0.120634028603673,0.10774964149524,0.337260166188229,0.062024612031302,0.467286751206154,0,0,0,0.0440407241264263,0,0,0,0,0,0,0.268067671581626,0,0,0.0323997907210197,0,0,0,0.121157999970798,0,0.298970907696164,0,0.0640322205040047,0.299634479874615,0,0,0,0,0,0.0420118584407915,0,0.21494058611927,0,0.0840237168815831,0.0440407241264263,0,0.121450345705599,0.185722801069447,0.120634028603673,0,0,0,0,0.0440407241264263,0,0.174249380869276,0,0,0,0.154396651940988,0,0,0.0440407241264263,0.280943424740641,0,0.510716377126755,0.1449723727285,0,0.485502831182371,0,0,0,0,0.185722801069447,0,0.120634028603673,0,0.315398374083619,0,0,0.415125886667995,0,0,0,0,0.0220203620632132,0,0,0,0,0,-0.019383951250715,0,0,0,0.208514060017288,0.411184999151176,0.0220203620632132,0,0.306132212046779,0,0.334555718415771,0.358931819271599,0,0,0.119210184411286,0,0,0.22469047929786,0.0440407241264263,0,0,0,0,0,0.0640322205040047,0,0,0,0,-0.00351219338773731,0.154396651940988,0,0,0.0843581865368086,0.12712067038516,0.0840237168815831,0,0.127935253862379,0,0,0 | |||
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| |||
|rna_box=118 | |rna_box=118 | ||
|rna_catalog_number=3H100-10-10 | |rna_catalog_number=3H100-10-10 | ||
Line 55: | Line 82: | ||
|rna_tube_id=118C2 | |rna_tube_id=118C2 | ||
|rna_weight_ug=10 | |rna_weight_ug=10 | ||
|rnaseq_library_id=SRhi10005.ACTTGA | |||
|sample_age=46 | |sample_age=46 | ||
|sample_category=primary cells | |||
|sample_cell_catalog=N/A | |sample_cell_catalog=N/A | ||
|sample_cell_line= | |sample_cell_line= | ||
Line 68: | Line 97: | ||
|sample_ethnicity=C | |sample_ethnicity=C | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;4.65931183639571e-221!GO:0043227;membrane-bound organelle;2.69539927700168e-160!GO:0043231;intracellular membrane-bound organelle;4.40478100067648e-160!GO:0043226;organelle;5.06653182398363e-149!GO:0043229;intracellular organelle;2.40932637858623e-148!GO:0005737;cytoplasm;6.78631752795855e-126!GO:0005634;nucleus;3.31272925900273e-87!GO:0043170;macromolecule metabolic process;2.35114080665041e-86!GO:0044422;organelle part;7.68443857665779e-83!GO:0044237;cellular metabolic process;1.10259333487693e-81!GO:0044446;intracellular organelle part;2.12407906859786e-81!GO:0044238;primary metabolic process;5.87297132846124e-81!GO:0005515;protein binding;6.35475132537947e-78!GO:0044444;cytoplasmic part;2.41475385931045e-77!GO:0032991;macromolecular complex;1.61484087630173e-69!GO:0044428;nuclear part;1.22679549836019e-65!GO:0003723;RNA binding;7.03158894866987e-65!GO:0043283;biopolymer metabolic process;2.65555222830915e-60!GO:0030529;ribonucleoprotein complex;7.37570106831587e-56!GO:0010467;gene expression;7.31126843662836e-51!GO:0043233;organelle lumen;7.4962437941608e-51!GO:0031974;membrane-enclosed lumen;7.4962437941608e-51!GO:0019538;protein metabolic process;1.04184293223352e-48!GO:0044267;cellular protein metabolic process;5.6157074430727e-46!GO:0044260;cellular macromolecule metabolic process;2.30002441798395e-45!GO:0033036;macromolecule localization;4.11182825036562e-45!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;9.08833275615786e-44!GO:0015031;protein transport;9.08833275615786e-44!GO:0045184;establishment of protein localization;1.84155763749234e-42!GO:0006412;translation;6.7813697270193e-42!GO:0008104;protein localization;1.37684685533626e-41!GO:0031981;nuclear lumen;1.8321134390087e-41!GO:0016071;mRNA metabolic process;1.53890965141665e-36!GO:0006396;RNA processing;2.49064151312904e-36!GO:0043234;protein complex;3.88233253113966e-36!GO:0016043;cellular component organization and biogenesis;8.75635645777024e-33!GO:0008380;RNA splicing;1.97016935768077e-31!GO:0012501;programmed cell death;3.21026828779991e-31!GO:0006915;apoptosis;3.31746502434433e-31!GO:0003676;nucleic acid binding;3.31746502434433e-31!GO:0005829;cytosol;1.2163377523421e-30!GO:0031090;organelle membrane;1.89367480615353e-30!GO:0009059;macromolecule biosynthetic process;3.26188752331088e-30!GO:0046907;intracellular transport;3.60376186676869e-30!GO:0008219;cell death;1.15949394634787e-29!GO:0016265;death;1.15949394634787e-29!GO:0005739;mitochondrion;2.00115388225885e-29!GO:0006397;mRNA processing;2.10729436915576e-29!GO:0006886;intracellular protein transport;4.55855647242734e-29!GO:0005840;ribosome;8.09126007272866e-29!GO:0016070;RNA metabolic process;3.26522362095022e-28!GO:0031967;organelle envelope;5.16180439807211e-28!GO:0031975;envelope;8.64852373550624e-28!GO:0005654;nucleoplasm;2.8657780573619e-27!GO:0000166;nucleotide binding;1.02818044416946e-25!GO:0003735;structural constituent of ribosome;2.07823598601866e-25!GO:0065003;macromolecular complex assembly;4.30566621890281e-25!GO:0033279;ribosomal subunit;5.71505485781891e-24!GO:0050794;regulation of cellular process;1.2043625657986e-23!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.32194768111464e-23!GO:0044249;cellular biosynthetic process;1.97678867167968e-23!GO:0005681;spliceosome;2.00323298529571e-23!GO:0043412;biopolymer modification;2.04489893857222e-23!GO:0051641;cellular localization;2.9940369499885e-23!GO:0051649;establishment of cellular localization;3.28098223406993e-23!GO:0008134;transcription factor binding;5.38876882351275e-23!GO:0009058;biosynthetic process;5.9434258991623e-23!GO:0044451;nucleoplasm part;6.39701158947727e-23!GO:0006259;DNA metabolic process;2.37133669135637e-22!GO:0022607;cellular component assembly;3.35209918558414e-22!GO:0044429;mitochondrial part;6.99586583636182e-22!GO:0006512;ubiquitin cycle;1.11997398353219e-21!GO:0042981;regulation of apoptosis;1.41998178007916e-21!GO:0044445;cytosolic part;2.69598327232704e-21!GO:0043067;regulation of programmed cell death;2.96549951017404e-21!GO:0006464;protein modification process;3.51125945825264e-21!GO:0043687;post-translational protein modification;3.91694948581247e-21!GO:0006996;organelle organization and biogenesis;1.32449307096784e-20!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.92674342395834e-20!GO:0032553;ribonucleotide binding;2.28589155586198e-19!GO:0032555;purine ribonucleotide binding;2.28589155586198e-19!GO:0050789;regulation of biological process;1.71428973632357e-18!GO:0044265;cellular macromolecule catabolic process;2.71685318691033e-18!GO:0017076;purine nucleotide binding;3.87790400336401e-18!GO:0002376;immune system process;1.73538773972966e-17!GO:0019941;modification-dependent protein catabolic process;2.45566216731472e-17!GO:0043632;modification-dependent macromolecule catabolic process;2.45566216731472e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;2.69465875641539e-17!GO:0006511;ubiquitin-dependent protein catabolic process;2.99293453506601e-17!GO:0006913;nucleocytoplasmic transport;3.40764361268027e-17!GO:0048523;negative regulation of cellular process;3.45655154905679e-17!GO:0044257;cellular protein catabolic process;6.32905151295133e-17!GO:0051169;nuclear transport;7.57510559412556e-17!GO:0017111;nucleoside-triphosphatase activity;1.09567302111856e-16!GO:0006605;protein targeting;1.36446158603484e-16!GO:0016462;pyrophosphatase activity;1.36446158603484e-16!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.51739614705752e-16!GO:0016817;hydrolase activity, acting on acid anhydrides;2.13756980100881e-16!GO:0016874;ligase activity;2.18886271975031e-16!GO:0016604;nuclear body;2.70875252493755e-16!GO:0005740;mitochondrial envelope;4.42847950378921e-16!GO:0007243;protein kinase cascade;7.40687612043893e-16!GO:0043285;biopolymer catabolic process;1.08061816085797e-15!GO:0019222;regulation of metabolic process;1.29289050354998e-15!GO:0031966;mitochondrial membrane;1.29289050354998e-15!GO:0022618;protein-RNA complex assembly;2.09936221541583e-15!GO:0005524;ATP binding;2.88561365207623e-15!GO:0006793;phosphorus metabolic process;3.57998369837872e-15!GO:0006796;phosphate metabolic process;3.57998369837872e-15!GO:0016192;vesicle-mediated transport;4.24166156595234e-15!GO:0019866;organelle inner membrane;4.77264966115309e-15!GO:0007242;intracellular signaling cascade;5.73624310778675e-15!GO:0048519;negative regulation of biological process;5.86817943523493e-15!GO:0032559;adenyl ribonucleotide binding;6.35201968012448e-15!GO:0003712;transcription cofactor activity;2.00028839647882e-14!GO:0006366;transcription from RNA polymerase II promoter;2.31966754765493e-14!GO:0065007;biological regulation;2.70510827763157e-14!GO:0006119;oxidative phosphorylation;4.36400024116678e-14!GO:0005730;nucleolus;8.40933537961575e-14!GO:0009057;macromolecule catabolic process;9.39345644755229e-14!GO:0048770;pigment granule;1.15196931695648e-13!GO:0042470;melanosome;1.15196931695648e-13!GO:0030554;adenyl nucleotide binding;1.22090768429499e-13!GO:0016607;nuclear speck;1.52655432473456e-13!GO:0006325;establishment and/or maintenance of chromatin architecture;2.11929518319588e-13!GO:0016310;phosphorylation;2.46634669224083e-13!GO:0007249;I-kappaB kinase/NF-kappaB cascade;3.89441577983505e-13!GO:0008135;translation factor activity, nucleic acid binding;4.3841602011476e-13!GO:0005635;nuclear envelope;6.93659004040195e-13!GO:0007049;cell cycle;7.63179166195251e-13!GO:0051246;regulation of protein metabolic process;9.44181095793685e-13!GO:0015935;small ribosomal subunit;1.07749320430911e-12!GO:0006955;immune response;1.16851202700637e-12!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.30777649576285e-12!GO:0006323;DNA packaging;1.34139461758704e-12!GO:0005743;mitochondrial inner membrane;1.39840699618394e-12!GO:0030163;protein catabolic process;1.59327766429631e-12!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.82440265246839e-12!GO:0031323;regulation of cellular metabolic process;2.05488435463737e-12!GO:0015934;large ribosomal subunit;2.37040961783917e-12!GO:0051276;chromosome organization and biogenesis;2.93908002304753e-12!GO:0012505;endomembrane system;4.33531224591227e-12!GO:0065009;regulation of a molecular function;4.3942950022889e-12!GO:0043228;non-membrane-bound organelle;5.23654031400248e-12!GO:0043232;intracellular non-membrane-bound organelle;5.23654031400248e-12!GO:0043069;negative regulation of programmed cell death;5.81003584155368e-12!GO:0017038;protein import;7.67707496647682e-12!GO:0043066;negative regulation of apoptosis;8.6984043668687e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.13609289568226e-11!GO:0044248;cellular catabolic process;1.27058553305987e-11!GO:0031965;nuclear membrane;1.35754978542693e-11!GO:0005794;Golgi apparatus;2.34270073770564e-11!GO:0016568;chromatin modification;2.38360088569639e-11!GO:0008639;small protein conjugating enzyme activity;4.00912156698053e-11!GO:0005768;endosome;4.69427734470547e-11!GO:0006916;anti-apoptosis;4.85876338606771e-11!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;5.36826346151942e-11!GO:0000398;nuclear mRNA splicing, via spliceosome;5.36826346151942e-11!GO:0000375;RNA splicing, via transesterification reactions;5.36826346151942e-11!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;5.36826346151942e-11!GO:0004842;ubiquitin-protein ligase activity;6.33220315614759e-11!GO:0031324;negative regulation of cellular metabolic process;8.85171157787203e-11!GO:0000502;proteasome complex (sensu Eukaryota);1.21048437323478e-10!GO:0019787;small conjugating protein ligase activity;1.50330400082836e-10!GO:0044455;mitochondrial membrane part;1.92154667968724e-10!GO:0010468;regulation of gene expression;2.5299308626621e-10!GO:0006606;protein import into nucleus;2.58946054762817e-10!GO:0051170;nuclear import;2.71226471366347e-10!GO:0003743;translation initiation factor activity;2.96725805587649e-10!GO:0048522;positive regulation of cellular process;4.62495381184532e-10!GO:0045321;leukocyte activation;5.36778224390608e-10!GO:0016564;transcription repressor activity;5.93314354056718e-10!GO:0006350;transcription;6.11454356544091e-10!GO:0004386;helicase activity;6.19353709113605e-10!GO:0051726;regulation of cell cycle;6.46772893021558e-10!GO:0006413;translational initiation;6.48719337136638e-10!GO:0006457;protein folding;6.56154147617374e-10!GO:0044453;nuclear membrane part;6.56813584124022e-10!GO:0006446;regulation of translational initiation;7.60973659704491e-10!GO:0006974;response to DNA damage stimulus;8.85611935275861e-10!GO:0005773;vacuole;1.14853919998852e-09!GO:0000074;regulation of progression through cell cycle;1.19387907546224e-09!GO:0009892;negative regulation of metabolic process;1.55584030509445e-09!GO:0016887;ATPase activity;1.68895237921795e-09!GO:0043065;positive regulation of apoptosis;1.74227301688115e-09!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.94020645069669e-09!GO:0048193;Golgi vesicle transport;1.96121957329393e-09!GO:0046649;lymphocyte activation;1.96121957329393e-09!GO:0042623;ATPase activity, coupled;1.96121957329393e-09!GO:0016563;transcription activator activity;2.25102220785069e-09!GO:0043068;positive regulation of programmed cell death;2.78584432585867e-09!GO:0005746;mitochondrial respiratory chain;3.34044666548308e-09!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.44469978147691e-09!GO:0003713;transcription coactivator activity;4.45925477505849e-09!GO:0019899;enzyme binding;4.8686996304902e-09!GO:0006917;induction of apoptosis;6.86917131988024e-09!GO:0007264;small GTPase mediated signal transduction;7.1225886061538e-09!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.28561502610113e-09!GO:0000323;lytic vacuole;7.70265205237014e-09!GO:0005764;lysosome;7.70265205237014e-09!GO:0016481;negative regulation of transcription;8.42218625871928e-09!GO:0048518;positive regulation of biological process;8.79720698529366e-09!GO:0008026;ATP-dependent helicase activity;9.22708701971907e-09!GO:0012502;induction of programmed cell death;1.2901469765274e-08!GO:0050136;NADH dehydrogenase (quinone) activity;1.34099838629452e-08!GO:0003954;NADH dehydrogenase activity;1.34099838629452e-08!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.34099838629452e-08!GO:0006417;regulation of translation;1.38400301256844e-08!GO:0050657;nucleic acid transport;1.53892765709236e-08!GO:0051236;establishment of RNA localization;1.53892765709236e-08!GO:0050658;RNA transport;1.53892765709236e-08!GO:0016881;acid-amino acid ligase activity;1.72450789613612e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.8136268079314e-08!GO:0006403;RNA localization;2.01450976431531e-08!GO:0022402;cell cycle process;2.37113879743898e-08!GO:0042110;T cell activation;2.72287854160378e-08!GO:0005643;nuclear pore;3.30228999250268e-08!GO:0009967;positive regulation of signal transduction;3.38224490025396e-08!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;4.19658668191594e-08!GO:0031980;mitochondrial lumen;5.04134075766342e-08!GO:0005759;mitochondrial matrix;5.04134075766342e-08!GO:0001775;cell activation;5.18137450063785e-08!GO:0045786;negative regulation of progression through cell cycle;5.5167855784718e-08!GO:0050790;regulation of catalytic activity;5.74932858339143e-08!GO:0009966;regulation of signal transduction;7.87413105923653e-08!GO:0019829;cation-transporting ATPase activity;1.06865724357488e-07!GO:0006357;regulation of transcription from RNA polymerase II promoter;1.23314247520159e-07!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.43791377374857e-07!GO:0006950;response to stress;1.7011731179008e-07!GO:0006281;DNA repair;1.77369133406257e-07!GO:0005783;endoplasmic reticulum;1.84881012811485e-07!GO:0042775;organelle ATP synthesis coupled electron transport;1.92739265678324e-07!GO:0042773;ATP synthesis coupled electron transport;1.92739265678324e-07!GO:0045449;regulation of transcription;1.93267172620877e-07!GO:0051082;unfolded protein binding;2.00972208462778e-07!GO:0051186;cofactor metabolic process;2.12566358566046e-07!GO:0032774;RNA biosynthetic process;2.24295348979879e-07!GO:0006351;transcription, DNA-dependent;2.32660887092997e-07!GO:0016787;hydrolase activity;2.59124040851238e-07!GO:0006333;chromatin assembly or disassembly;2.68701204344784e-07!GO:0031326;regulation of cellular biosynthetic process;2.74690789635298e-07!GO:0032446;protein modification by small protein conjugation;2.82452454349542e-07!GO:0030695;GTPase regulator activity;3.1152570826139e-07!GO:0008565;protein transporter activity;3.16900487031545e-07!GO:0016740;transferase activity;3.88301757165036e-07!GO:0005770;late endosome;4.00399910523557e-07!GO:0030964;NADH dehydrogenase complex (quinone);4.03800909260293e-07!GO:0045271;respiratory chain complex I;4.03800909260293e-07!GO:0005747;mitochondrial respiratory chain complex I;4.03800909260293e-07!GO:0009889;regulation of biosynthetic process;4.23251223750666e-07!GO:0016567;protein ubiquitination;5.13221351698639e-07!GO:0003924;GTPase activity;5.13221351698639e-07!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;5.26571471658066e-07!GO:0051028;mRNA transport;5.31852468330887e-07!GO:0006461;protein complex assembly;6.34233346960691e-07!GO:0004674;protein serine/threonine kinase activity;7.06895269134403e-07!GO:0005694;chromosome;7.16245762198498e-07!GO:0009615;response to virus;7.70932120763583e-07!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;7.97640287102012e-07!GO:0003714;transcription corepressor activity;8.54817201316411e-07!GO:0005525;GTP binding;9.57161260355764e-07!GO:0043566;structure-specific DNA binding;1.0427787847592e-06!GO:0065004;protein-DNA complex assembly;1.04675333418058e-06!GO:0008047;enzyme activator activity;1.16899588788243e-06!GO:0003697;single-stranded DNA binding;1.23634569668769e-06!GO:0060090;molecular adaptor activity;1.51967334419494e-06!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.68674019601678e-06!GO:0046930;pore complex;1.69820401515269e-06!GO:0048468;cell development;1.77992133389553e-06!GO:0042254;ribosome biogenesis and assembly;1.78624549305309e-06!GO:0009259;ribonucleotide metabolic process;2.14008506686747e-06!GO:0005793;ER-Golgi intermediate compartment;2.23098553667958e-06!GO:0009056;catabolic process;2.59501092900005e-06!GO:0008270;zinc ion binding;2.7404835806238e-06!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;3.0060133692223e-06!GO:0001772;immunological synapse;3.04616551473027e-06!GO:0065002;intracellular protein transport across a membrane;3.21102577545031e-06!GO:0015986;ATP synthesis coupled proton transport;3.38874836638992e-06!GO:0015985;energy coupled proton transport, down electrochemical gradient;3.38874836638992e-06!GO:0009260;ribonucleotide biosynthetic process;3.73397887518117e-06!GO:0009152;purine ribonucleotide biosynthetic process;4.14934619970096e-06!GO:0006401;RNA catabolic process;4.24024210226692e-06!GO:0044432;endoplasmic reticulum part;4.27271113068453e-06!GO:0044440;endosomal part;4.48091198889448e-06!GO:0010008;endosome membrane;4.48091198889448e-06!GO:0030532;small nuclear ribonucleoprotein complex;4.58999655833584e-06!GO:0000151;ubiquitin ligase complex;4.68664361582096e-06!GO:0006164;purine nucleotide biosynthetic process;4.78703172840097e-06!GO:0007265;Ras protein signal transduction;5.23126120002965e-06!GO:0009150;purine ribonucleotide metabolic process;5.39568046262714e-06!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;5.44318095231871e-06!GO:0006732;coenzyme metabolic process;5.62271380759051e-06!GO:0008632;apoptotic program;5.69564352069817e-06!GO:0006163;purine nucleotide metabolic process;5.74728082580381e-06!GO:0045892;negative regulation of transcription, DNA-dependent;6.21233104271613e-06!GO:0006355;regulation of transcription, DNA-dependent;7.28243544795539e-06!GO:0016301;kinase activity;7.61472605622163e-06!GO:0009719;response to endogenous stimulus;7.96827174673484e-06!GO:0000785;chromatin;8.41254062290489e-06!GO:0030097;hemopoiesis;9.12070934769718e-06!GO:0044427;chromosomal part;9.66572738529866e-06!GO:0005839;proteasome core complex (sensu Eukaryota);1.2127067492188e-05!GO:0051168;nuclear export;1.24726484828292e-05!GO:0003724;RNA helicase activity;1.37470134994519e-05!GO:0016773;phosphotransferase activity, alcohol group as acceptor;1.37470134994519e-05!GO:0048475;coated membrane;1.52468134952766e-05!GO:0030117;membrane coat;1.52468134952766e-05!GO:0005083;small GTPase regulator activity;1.65726397625045e-05!GO:0032561;guanyl ribonucleotide binding;1.67248922353441e-05!GO:0019001;guanyl nucleotide binding;1.67248922353441e-05!GO:0002757;immune response-activating signal transduction;1.73970933671709e-05!GO:0009060;aerobic respiration;1.90443900596712e-05!GO:0005096;GTPase activator activity;2.09508311981837e-05!GO:0030120;vesicle coat;2.14308621097322e-05!GO:0030662;coated vesicle membrane;2.14308621097322e-05!GO:0016469;proton-transporting two-sector ATPase complex;2.29454581943911e-05!GO:0006402;mRNA catabolic process;2.41399791308925e-05!GO:0005057;receptor signaling protein activity;2.45481089688365e-05!GO:0015078;hydrogen ion transmembrane transporter activity;2.67039482516832e-05!GO:0002764;immune response-regulating signal transduction;2.81710998501729e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;2.9814354853161e-05!GO:0006754;ATP biosynthetic process;3.06787901287252e-05!GO:0006753;nucleoside phosphate metabolic process;3.06787901287252e-05!GO:0005070;SH3/SH2 adaptor activity;3.16871782458798e-05!GO:0006888;ER to Golgi vesicle-mediated transport;3.25737878412775e-05!GO:0016197;endosome transport;3.34624422989881e-05!GO:0009142;nucleoside triphosphate biosynthetic process;3.36027615728729e-05!GO:0009201;ribonucleoside triphosphate biosynthetic process;3.36027615728729e-05!GO:0051336;regulation of hydrolase activity;4.03236218406799e-05!GO:0031252;leading edge;4.04205506099496e-05!GO:0000245;spliceosome assembly;4.05372446325474e-05!GO:0009199;ribonucleoside triphosphate metabolic process;4.22210063092714e-05!GO:0006468;protein amino acid phosphorylation;4.3993607635166e-05!GO:0051251;positive regulation of lymphocyte activation;4.74689688106744e-05!GO:0004298;threonine endopeptidase activity;5.23707583015016e-05!GO:0002429;immune response-activating cell surface receptor signaling pathway;5.32830927317435e-05!GO:0046034;ATP metabolic process;5.44256226568708e-05!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;5.44256226568708e-05!GO:0009145;purine nucleoside triphosphate biosynthetic process;5.44256226568708e-05!GO:0042175;nuclear envelope-endoplasmic reticulum network;5.50279148655354e-05!GO:0045259;proton-transporting ATP synthase complex;5.71139393046268e-05!GO:0009893;positive regulation of metabolic process;6.1438908716212e-05!GO:0005774;vacuolar membrane;6.2847336125578e-05!GO:0009205;purine ribonucleoside triphosphate metabolic process;6.63878602584384e-05!GO:0009144;purine nucleoside triphosphate metabolic process;6.63878602584384e-05!GO:0005789;endoplasmic reticulum membrane;6.88371861098799e-05!GO:0002520;immune system development;7.80538072578819e-05!GO:0002768;immune response-regulating cell surface receptor signaling pathway;8.50649151670977e-05!GO:0009141;nucleoside triphosphate metabolic process;8.70881229570563e-05!GO:0046822;regulation of nucleocytoplasmic transport;9.41694694836459e-05!GO:0008234;cysteine-type peptidase activity;0.000105139104797005!GO:0051090;regulation of transcription factor activity;0.000106457970209089!GO:0016363;nuclear matrix;0.000106937553286827!GO:0006260;DNA replication;0.00010901503572278!GO:0016044;membrane organization and biogenesis;0.000111341976420888!GO:0006613;cotranslational protein targeting to membrane;0.000113816680458791!GO:0042101;T cell receptor complex;0.000115121243783889!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000122384770444152!GO:0051188;cofactor biosynthetic process;0.000125263260305366!GO:0031982;vesicle;0.000131574243648991!GO:0016072;rRNA metabolic process;0.000133731195850861!GO:0006364;rRNA processing;0.000139581431262876!GO:0005813;centrosome;0.000166299776428424!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.000178429038990874!GO:0005765;lysosomal membrane;0.00017869286424379!GO:0051223;regulation of protein transport;0.000183424031055037!GO:0008186;RNA-dependent ATPase activity;0.000196073268423664!GO:0051338;regulation of transferase activity;0.000196531777190874!GO:0001816;cytokine production;0.000208124653071586!GO:0005769;early endosome;0.000228327590693123!GO:0005761;mitochondrial ribosome;0.000228327590693123!GO:0000313;organellar ribosome;0.000228327590693123!GO:0044431;Golgi apparatus part;0.000228708310506294!GO:0022415;viral reproductive process;0.000235947873959446!GO:0045333;cellular respiration;0.000239163299087507!GO:0001819;positive regulation of cytokine production;0.000252199503709116!GO:0005885;Arp2/3 protein complex;0.000253719079676588!GO:0044437;vacuolar part;0.00025551515793901!GO:0045941;positive regulation of transcription;0.000256483259899502!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.000257857078645073!GO:0004812;aminoacyl-tRNA ligase activity;0.000257857078645073!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.000257857078645073!GO:0051427;hormone receptor binding;0.000257857078645073!GO:0046983;protein dimerization activity;0.000266822145735638!GO:0031902;late endosome membrane;0.000268644874234534!GO:0002521;leukocyte differentiation;0.00030325102483206!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000325939943065015!GO:0043623;cellular protein complex assembly;0.000332588985076888!GO:0043549;regulation of kinase activity;0.000333210023849924!GO:0048534;hemopoietic or lymphoid organ development;0.000336225323674959!GO:0000278;mitotic cell cycle;0.000336225323674959!GO:0007005;mitochondrion organization and biogenesis;0.000364288119853149!GO:0031497;chromatin assembly;0.000370402220049023!GO:0005667;transcription factor complex;0.000374288811229869!GO:0016779;nucleotidyltransferase activity;0.000414840339086157!GO:0045893;positive regulation of transcription, DNA-dependent;0.000443942644546117!GO:0046914;transition metal ion binding;0.000443942644546117!GO:0006399;tRNA metabolic process;0.000444888566959309!GO:0031410;cytoplasmic vesicle;0.000448928686361953!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000456102375398877!GO:0050865;regulation of cell activation;0.000456102375398877!GO:0009108;coenzyme biosynthetic process;0.000456182826739886!GO:0035257;nuclear hormone receptor binding;0.000474747915909653!GO:0007050;cell cycle arrest;0.000476319352405104!GO:0003729;mRNA binding;0.000489835860530925!GO:0043038;amino acid activation;0.000507868736376093!GO:0006418;tRNA aminoacylation for protein translation;0.000507868736376093!GO:0043039;tRNA aminoacylation;0.000507868736376093!GO:0006334;nucleosome assembly;0.000528503108797572!GO:0006099;tricarboxylic acid cycle;0.000528503108797572!GO:0046356;acetyl-CoA catabolic process;0.000528503108797572!GO:0051249;regulation of lymphocyte activation;0.00053781231349892!GO:0048471;perinuclear region of cytoplasm;0.000555034455119883!GO:0009055;electron carrier activity;0.000561164212198395!GO:0004004;ATP-dependent RNA helicase activity;0.000571755237194449!GO:0005798;Golgi-associated vesicle;0.00058818301590152!GO:0032940;secretion by cell;0.000611635555331103!GO:0006607;NLS-bearing substrate import into nucleus;0.000639666611187524!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.000660579710925571!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0006984373453378!GO:0015399;primary active transmembrane transporter activity;0.0006984373453378!GO:0008654;phospholipid biosynthetic process;0.0006984373453378!GO:0018193;peptidyl-amino acid modification;0.000715492479603268!GO:0005815;microtubule organizing center;0.000722302174324506!GO:0031325;positive regulation of cellular metabolic process;0.000751575073345317!GO:0045859;regulation of protein kinase activity;0.000776407947323076!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.000791124651731424!GO:0042802;identical protein binding;0.000796586756289357!GO:0006919;caspase activation;0.00082696497088608!GO:0031988;membrane-bound vesicle;0.00082696497088608!GO:0005637;nuclear inner membrane;0.000834114242995273!GO:0050851;antigen receptor-mediated signaling pathway;0.000858317469774676!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000858317469774676!GO:0009607;response to biotic stimulus;0.000865091689279484!GO:0006752;group transfer coenzyme metabolic process;0.000894853085194118!GO:0004715;non-membrane spanning protein tyrosine kinase activity;0.000919681421048173!GO:0001817;regulation of cytokine production;0.000929840217406984!GO:0003677;DNA binding;0.000970141879716101!GO:0043087;regulation of GTPase activity;0.00100776667872001!GO:0006612;protein targeting to membrane;0.00106925581635355!GO:0030099;myeloid cell differentiation;0.00114952498727057!GO:0033157;regulation of intracellular protein transport;0.00117393210522318!GO:0042306;regulation of protein import into nucleus;0.00117393210522318!GO:0050870;positive regulation of T cell activation;0.00122837005092672!GO:0006611;protein export from nucleus;0.00124743127016563!GO:0006084;acetyl-CoA metabolic process;0.00138517854574202!GO:0030036;actin cytoskeleton organization and biogenesis;0.00141315346936576!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00149328121023457!GO:0043280;positive regulation of caspase activity;0.00153182119521367!GO:0007034;vacuolar transport;0.00159913085800854!GO:0003690;double-stranded DNA binding;0.001600913899261!GO:0043281;regulation of caspase activity;0.00163072333618075!GO:0030217;T cell differentiation;0.00163072333618075!GO:0016023;cytoplasmic membrane-bound vesicle;0.00165227000851577!GO:0042113;B cell activation;0.00165227000851577!GO:0017091;AU-rich element binding;0.00169910081226139!GO:0050779;RNA destabilization;0.00169910081226139!GO:0000289;poly(A) tail shortening;0.00169910081226139!GO:0019904;protein domain specific binding;0.00169910081226139!GO:0051092;activation of NF-kappaB transcription factor;0.00175297468365568!GO:0005741;mitochondrial outer membrane;0.00180145181530574!GO:0030658;transport vesicle membrane;0.00206264158792764!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00207540244513745!GO:0030098;lymphocyte differentiation;0.00210317515680542!GO:0019221;cytokine and chemokine mediated signaling pathway;0.00212020384290261!GO:0045637;regulation of myeloid cell differentiation;0.00219053238073308!GO:0051187;cofactor catabolic process;0.00229250786526075!GO:0050863;regulation of T cell activation;0.00237663837566124!GO:0006891;intra-Golgi vesicle-mediated transport;0.00243415784838202!GO:0004672;protein kinase activity;0.00245419495049771!GO:0015631;tubulin binding;0.00250732760187651!GO:0042287;MHC protein binding;0.00266841878543814!GO:0001726;ruffle;0.00276984971297338!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00278072829317594!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.00288057969537657!GO:0051252;regulation of RNA metabolic process;0.00288057969537657!GO:0006352;transcription initiation;0.0029433349653873!GO:0043021;ribonucleoprotein binding;0.00309060508230226!GO:0043492;ATPase activity, coupled to movement of substances;0.00309060508230226!GO:0043488;regulation of mRNA stability;0.00309060508230226!GO:0043487;regulation of RNA stability;0.00309060508230226!GO:0045045;secretory pathway;0.00313917710548836!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00317047025962078!GO:0019783;small conjugating protein-specific protease activity;0.00319425679608446!GO:0019867;outer membrane;0.00319557890977738!GO:0030384;phosphoinositide metabolic process;0.00322342751931444!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00325486394180025!GO:0042990;regulation of transcription factor import into nucleus;0.00325486394180025!GO:0042991;transcription factor import into nucleus;0.00325486394180025!GO:0050871;positive regulation of B cell activation;0.0032962408551534!GO:0005099;Ras GTPase activator activity;0.00339950602024478!GO:0008287;protein serine/threonine phosphatase complex;0.0034067343043999!GO:0032318;regulation of Ras GTPase activity;0.00341679705932713!GO:0006650;glycerophospholipid metabolic process;0.00341679705932713!GO:0000139;Golgi membrane;0.00343146724610419!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00343470428639483!GO:0043433;negative regulation of transcription factor activity;0.00351328325583585!GO:0009109;coenzyme catabolic process;0.00360892396137385!GO:0008624;induction of apoptosis by extracellular signals;0.00363019299698242!GO:0031968;organelle outer membrane;0.00363461788394376!GO:0016311;dephosphorylation;0.00364028352412871!GO:0002252;immune effector process;0.00377542808766314!GO:0031625;ubiquitin protein ligase binding;0.00378615511048654!GO:0004843;ubiquitin-specific protease activity;0.00382243022506165!GO:0016791;phosphoric monoester hydrolase activity;0.00382695578694167!GO:0006261;DNA-dependent DNA replication;0.00417036490786905!GO:0042613;MHC class II protein complex;0.00417922010664547!GO:0006897;endocytosis;0.00427433819659182!GO:0010324;membrane invagination;0.00427433819659182!GO:0005852;eukaryotic translation initiation factor 3 complex;0.0043611364342064!GO:0019843;rRNA binding;0.00452531599125385!GO:0016251;general RNA polymerase II transcription factor activity;0.00454925162225095!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00455471529379626!GO:0045058;T cell selection;0.00475008955068428!GO:0030660;Golgi-associated vesicle membrane;0.00500320025643901!GO:0004722;protein serine/threonine phosphatase activity;0.00501941248202635!GO:0005048;signal sequence binding;0.00503132492416871!GO:0030218;erythrocyte differentiation;0.00505309271530734!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00518627837933383!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00518627837933383!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00518627837933383!GO:0006338;chromatin remodeling;0.00521988760118139!GO:0016584;nucleosome positioning;0.00526580144137236!GO:0006414;translational elongation;0.00539325634060125!GO:0007041;lysosomal transport;0.00547669965177089!GO:0030258;lipid modification;0.00547669965177089!GO:0009117;nucleotide metabolic process;0.00550513393937098!GO:0051098;regulation of binding;0.00554276060584017!GO:0051049;regulation of transport;0.00568694183722045!GO:0030118;clathrin coat;0.00575076609019145!GO:0051091;positive regulation of transcription factor activity;0.0057675539334439!GO:0003725;double-stranded RNA binding;0.00588098818832649!GO:0002440;production of molecular mediator of immune response;0.00591150547160734!GO:0033116;ER-Golgi intermediate compartment membrane;0.00591537810147741!GO:0051329;interphase of mitotic cell cycle;0.00593633960986777!GO:0051235;maintenance of localization;0.0060564981908818!GO:0002274;myeloid leukocyte activation;0.00628702945291594!GO:0000118;histone deacetylase complex;0.00656682821065277!GO:0008139;nuclear localization sequence binding;0.00657564454865637!GO:0006310;DNA recombination;0.00662049232563473!GO:0046519;sphingoid metabolic process;0.00676771365134916!GO:0015630;microtubule cytoskeleton;0.0068902339815256!GO:0004221;ubiquitin thiolesterase activity;0.0068902339815256!GO:0043085;positive regulation of catalytic activity;0.00723738770913193!GO:0019901;protein kinase binding;0.00729659750255187!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0073122795407765!GO:0006672;ceramide metabolic process;0.00731911642613688!GO:0045646;regulation of erythrocyte differentiation;0.00736924136509622!GO:0046966;thyroid hormone receptor binding;0.00748462060412054!GO:0032386;regulation of intracellular transport;0.00749690091516204!GO:0008017;microtubule binding;0.007581177208649!GO:0051789;response to protein stimulus;0.00781859687511749!GO:0006986;response to unfolded protein;0.00781859687511749!GO:0030518;steroid hormone receptor signaling pathway;0.00781859687511749!GO:0019079;viral genome replication;0.00781859687511749!GO:0048487;beta-tubulin binding;0.0078455486228217!GO:0051056;regulation of small GTPase mediated signal transduction;0.0079902141700225!GO:0019058;viral infectious cycle;0.00816015571070413!GO:0004428;inositol or phosphatidylinositol kinase activity;0.00834325971648984!GO:0031072;heat shock protein binding;0.00867875132956896!GO:0051325;interphase;0.00891845864600605!GO:0008637;apoptotic mitochondrial changes;0.00895697294406815!GO:0003746;translation elongation factor activity;0.00907152946228849!GO:0019882;antigen processing and presentation;0.00917877786367115!GO:0045603;positive regulation of endothelial cell differentiation;0.00925966716258244!GO:0006818;hydrogen transport;0.00940070770479844!GO:0043621;protein self-association;0.00940070770479844!GO:0030041;actin filament polymerization;0.00941396667244266!GO:0046578;regulation of Ras protein signal transduction;0.00950401918850205!GO:0006405;RNA export from nucleus;0.00962464211137818!GO:0005684;U2-dependent spliceosome;0.00967966775431387!GO:0000082;G1/S transition of mitotic cell cycle;0.00977204662897707!GO:0008629;induction of apoptosis by intracellular signals;0.0098390268831026!GO:0002443;leukocyte mediated immunity;0.00995756236034397!GO:0007259;JAK-STAT cascade;0.0101171425072688!GO:0019220;regulation of phosphate metabolic process;0.0103647384810378!GO:0051174;regulation of phosphorus metabolic process;0.0103647384810378!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0106643079580168!GO:0002819;regulation of adaptive immune response;0.0106643079580168!GO:0045792;negative regulation of cell size;0.0109488546699865!GO:0015992;proton transport;0.0109897301858495!GO:0033673;negative regulation of kinase activity;0.0111936436038388!GO:0006469;negative regulation of protein kinase activity;0.0111936436038388!GO:0030029;actin filament-based process;0.0113663157483961!GO:0031098;stress-activated protein kinase signaling pathway;0.0114912166064887!GO:0047485;protein N-terminus binding;0.0114982964320582!GO:0016585;chromatin remodeling complex;0.0114982964320582!GO:0030521;androgen receptor signaling pathway;0.011578950384492!GO:0043300;regulation of leukocyte degranulation;0.0116329033302523!GO:0051059;NF-kappaB binding;0.0120749234673584!GO:0045576;mast cell activation;0.0125271670099802!GO:0045926;negative regulation of growth;0.0125483994626545!GO:0003702;RNA polymerase II transcription factor activity;0.0128842870635706!GO:0051345;positive regulation of hydrolase activity;0.0131540610847815!GO:0016605;PML body;0.0131671500273716!GO:0006643;membrane lipid metabolic process;0.0132576211270656!GO:0048500;signal recognition particle;0.0134502404431214!GO:0046467;membrane lipid biosynthetic process;0.0135511277533089!GO:0030127;COPII vesicle coat;0.0135986899421819!GO:0012507;ER to Golgi transport vesicle membrane;0.0135986899421819!GO:0051348;negative regulation of transferase activity;0.0136730128280527!GO:0030308;negative regulation of cell growth;0.0137316508123426!GO:0015923;mannosidase activity;0.0137965515722622!GO:0000165;MAPKKK cascade;0.0143715538758751!GO:0043299;leukocyte degranulation;0.0144311938236894!GO:0005669;transcription factor TFIID complex;0.0148055370063587!GO:0045746;negative regulation of Notch signaling pathway;0.0148325531945533!GO:0045069;regulation of viral genome replication;0.0148620913292745!GO:0030674;protein binding, bridging;0.0148671817666834!GO:0031901;early endosome membrane;0.0148799061655128!GO:0030867;rough endoplasmic reticulum membrane;0.0157066452753777!GO:0040029;regulation of gene expression, epigenetic;0.016944456707756!GO:0006984;ER-nuclear signaling pathway;0.0170116660397972!GO:0000209;protein polyubiquitination;0.017336100478515!GO:0003711;transcription elongation regulator activity;0.0173455134884365!GO:0004185;serine carboxypeptidase activity;0.0173455134884365!GO:0050900;leukocyte migration;0.0174087236491296!GO:0006595;polyamine metabolic process;0.0175981991657459!GO:0022890;inorganic cation transmembrane transporter activity;0.0179892749664739!GO:0004197;cysteine-type endopeptidase activity;0.017998940645019!GO:0019900;kinase binding;0.018490937527041!GO:0004177;aminopeptidase activity;0.0187762320037377!GO:0005521;lamin binding;0.0187762320037377!GO:0006376;mRNA splice site selection;0.0189317897456556!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0189317897456556!GO:0030134;ER to Golgi transport vesicle;0.0190195627524126!GO:0051051;negative regulation of transport;0.0191870745263217!GO:0007040;lysosome organization and biogenesis;0.0192109501058227!GO:0006968;cellular defense response;0.019273226728969!GO:0022403;cell cycle phase;0.0192870364523671!GO:0043414;biopolymer methylation;0.0193830110043816!GO:0046474;glycerophospholipid biosynthetic process;0.0198199746994732!GO:0019210;kinase inhibitor activity;0.0198638151688715!GO:0003682;chromatin binding;0.0202764312117232!GO:0004721;phosphoprotein phosphatase activity;0.0207597460475053!GO:0001516;prostaglandin biosynthetic process;0.0210701169254123!GO:0046457;prostanoid biosynthetic process;0.0210701169254123!GO:0017166;vinculin binding;0.0217779613976881!GO:0004860;protein kinase inhibitor activity;0.0217779613976881!GO:0030176;integral to endoplasmic reticulum membrane;0.0217779613976881!GO:0050811;GABA receptor binding;0.0218812972727289!GO:0007254;JNK cascade;0.0220572277636279!GO:0003899;DNA-directed RNA polymerase activity;0.0222134827769677!GO:0030522;intracellular receptor-mediated signaling pathway;0.0226329122856525!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0226560836592762!GO:0045047;protein targeting to ER;0.0226560836592762!GO:0033549;MAP kinase phosphatase activity;0.0229271186646778!GO:0017017;MAP kinase tyrosine/serine/threonine phosphatase activity;0.0229271186646778!GO:0045185;maintenance of protein localization;0.0229582178125877!GO:0050864;regulation of B cell activation;0.0230476781895167!GO:0046489;phosphoinositide biosynthetic process;0.0231069047328316!GO:0043022;ribosome binding;0.0239935166725623!GO:0043681;protein import into mitochondrion;0.0244774604268716!GO:0046854;phosphoinositide phosphorylation;0.0245070352653532!GO:0006470;protein amino acid dephosphorylation;0.0246933345335289!GO:0003678;DNA helicase activity;0.0250331644085003!GO:0022411;cellular component disassembly;0.0254951991552031!GO:0030119;AP-type membrane coat adaptor complex;0.0256765907745317!GO:0001667;ameboidal cell migration;0.0257289486273556!GO:0032027;myosin light chain binding;0.0257289486273556!GO:0005791;rough endoplasmic reticulum;0.0257374867518418!GO:0019883;antigen processing and presentation of endogenous antigen;0.0260387995284826!GO:0006383;transcription from RNA polymerase III promoter;0.0260710668879896!GO:0051052;regulation of DNA metabolic process;0.0264092060602095!GO:0030027;lamellipodium;0.0268878403808291!GO:0002467;germinal center formation;0.0270484487317834!GO:0016790;thiolester hydrolase activity;0.0272302392539267!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0280548978038902!GO:0000060;protein import into nucleus, translocation;0.0280737521052334!GO:0008312;7S RNA binding;0.0281524749494451!GO:0006367;transcription initiation from RNA polymerase II promoter;0.028478856115887!GO:0016788;hydrolase activity, acting on ester bonds;0.0285434559894069!GO:0032763;regulation of mast cell cytokine production;0.0286908345974115!GO:0032762;mast cell cytokine production;0.0286908345974115!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0300629241341014!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0300629241341014!GO:0007006;mitochondrial membrane organization and biogenesis;0.0300719024911111!GO:0000303;response to superoxide;0.0301086076936576!GO:0032507;maintenance of cellular protein localization;0.0304282175353354!GO:0002444;myeloid leukocyte mediated immunity;0.0305505259386485!GO:0009299;mRNA transcription;0.0306289705657867!GO:0032200;telomere organization and biogenesis;0.0315332110455098!GO:0000723;telomere maintenance;0.0315332110455098!GO:0045454;cell redox homeostasis;0.0319267163679459!GO:0006354;RNA elongation;0.0319267163679459!GO:0033367;protein localization in mast cell secretory granule;0.0319267163679459!GO:0033365;protein localization in organelle;0.0319267163679459!GO:0033371;T cell secretory granule organization and biogenesis;0.0319267163679459!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0319267163679459!GO:0033375;protease localization in T cell secretory granule;0.0319267163679459!GO:0042629;mast cell granule;0.0319267163679459!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0319267163679459!GO:0033364;mast cell secretory granule organization and biogenesis;0.0319267163679459!GO:0033380;granzyme B localization in T cell secretory granule;0.0319267163679459!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0319267163679459!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0319267163679459!GO:0033368;protease localization in mast cell secretory granule;0.0319267163679459!GO:0033366;protein localization in secretory granule;0.0319267163679459!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0319267163679459!GO:0033374;protein localization in T cell secretory granule;0.0319267163679459!GO:0008154;actin polymerization and/or depolymerization;0.0321585422984338!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.03216203041628!GO:0006914;autophagy;0.032358520832977!GO:0042108;positive regulation of cytokine biosynthetic process;0.0328801581437299!GO:0045086;positive regulation of interleukin-2 biosynthetic process;0.0329251390107439!GO:0046426;negative regulation of JAK-STAT cascade;0.0334936362237105!GO:0043304;regulation of mast cell degranulation;0.0334936362237105!GO:0030131;clathrin adaptor complex;0.0336152207973058!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0337823689250528!GO:0007033;vacuole organization and biogenesis;0.0337984755559857!GO:0001836;release of cytochrome c from mitochondria;0.0342008170067874!GO:0000287;magnesium ion binding;0.0342008170067874!GO:0030833;regulation of actin filament polymerization;0.0343547732551464!GO:0050671;positive regulation of lymphocyte proliferation;0.0354845028039364!GO:0032946;positive regulation of mononuclear cell proliferation;0.0354845028039364!GO:0002218;activation of innate immune response;0.0354845028039364!GO:0002758;innate immune response-activating signal transduction;0.0354845028039364!GO:0005762;mitochondrial large ribosomal subunit;0.0354845028039364!GO:0000315;organellar large ribosomal subunit;0.0354845028039364!GO:0051087;chaperone binding;0.0359441500542857!GO:0032623;interleukin-2 production;0.0361017544502265!GO:0030125;clathrin vesicle coat;0.0362216727721751!GO:0030665;clathrin coated vesicle membrane;0.0362216727721751!GO:0030149;sphingolipid catabolic process;0.0362433559604298!GO:0030133;transport vesicle;0.0363956817802468!GO:0046834;lipid phosphorylation;0.0366249551540262!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0366893715897112!GO:0008276;protein methyltransferase activity;0.0367579531522849!GO:0008286;insulin receptor signaling pathway;0.0369787119697403!GO:0043506;regulation of JNK activity;0.0369787119697403!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0370979118473023!GO:0002448;mast cell mediated immunity;0.037569327398964!GO:0043303;mast cell degranulation;0.037569327398964!GO:0046979;TAP2 binding;0.0376472573229935!GO:0046977;TAP binding;0.0376472573229935!GO:0046978;TAP1 binding;0.0376472573229935!GO:0050857;positive regulation of antigen receptor-mediated signaling pathway;0.0378494693898739!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.038016147896641!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0380545595121017!GO:0042608;T cell receptor binding;0.0383244684313851!GO:0045309;protein phosphorylated amino acid binding;0.0387501523243491!GO:0050792;regulation of viral reproduction;0.0387877666380258!GO:0048872;homeostasis of number of cells;0.039186155183526!GO:0051101;regulation of DNA binding;0.0392654905132856!GO:0033239;negative regulation of amine metabolic process;0.0392654905132856!GO:0045763;negative regulation of amino acid metabolic process;0.0392654905132856!GO:0001933;negative regulation of protein amino acid phosphorylation;0.0392654905132856!GO:0005869;dynactin complex;0.0393963554788488!GO:0035258;steroid hormone receptor binding;0.0396358311281936!GO:0045647;negative regulation of erythrocyte differentiation;0.0397434917204454!GO:0042348;NF-kappaB import into nucleus;0.0403651590425461!GO:0042345;regulation of NF-kappaB import into nucleus;0.0403651590425461!GO:0002250;adaptive immune response;0.040519030632691!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.040519030632691!GO:0048002;antigen processing and presentation of peptide antigen;0.0406983740155863!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.0419722140849001!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0423059250601048!GO:0006302;double-strand break repair;0.0430341783250729!GO:0006213;pyrimidine nucleoside metabolic process;0.043346925063328!GO:0000781;chromosome, telomeric region;0.0438862492672312!GO:0051050;positive regulation of transport;0.0439187794160805!GO:0015980;energy derivation by oxidation of organic compounds;0.0442247248431147!GO:0016569;covalent chromatin modification;0.0442247248431147!GO:0031461;cullin-RING ubiquitin ligase complex;0.0442627621157891!GO:0043407;negative regulation of MAP kinase activity;0.0448068229415175!GO:0044262;cellular carbohydrate metabolic process;0.0454204175134942!GO:0050852;T cell receptor signaling pathway;0.0457104342891651!GO:0006013;mannose metabolic process;0.0457104342891651!GO:0001562;response to protozoan;0.0462189931568721!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0463692751287139!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0463692751287139!GO:0000339;RNA cap binding;0.0465191790033148!GO:0032508;DNA duplex unwinding;0.0466179429185264!GO:0032392;DNA geometric change;0.0466179429185264!GO:0016505;apoptotic protease activator activity;0.0467431551837839!GO:0005085;guanyl-nucleotide exchange factor activity;0.047885914177099!GO:0051539;4 iron, 4 sulfur cluster binding;0.047885914177099!GO:0008383;manganese superoxide dismutase activity;0.047885914177099!GO:0001315;age-dependent response to reactive oxygen species;0.047885914177099!GO:0051707;response to other organism;0.0482730719660269!GO:0002718;regulation of cytokine production during immune response;0.0484315471619686!GO:0002367;cytokine production during immune response;0.0484315471619686!GO:0002700;regulation of production of molecular mediator of immune response;0.0484315471619686!GO:0045947;negative regulation of translational initiation;0.048445561590847!GO:0045621;positive regulation of lymphocyte differentiation;0.0484783175547351!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0486525848416412!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0486525848416412!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0486525848416412!GO:0000049;tRNA binding;0.0486838213247134!GO:0006661;phosphatidylinositol biosynthetic process;0.0488604867465852!GO:0002449;lymphocyte mediated immunity;0.048923443040112!GO:0001776;leukocyte homeostasis;0.0494764023538784!GO:0001784;phosphotyrosine binding;0.0495139924844702 | |||
|sample_id=11388 | |sample_id=11388 | ||
|sample_note= | |sample_note= | ||
Line 75: | Line 105: | ||
|sample_tissue=blood | |sample_tissue=blood | ||
|top_motifs=PAX3,7:3.00618570612;ETS1,2:2.83160872023;NFKB1_REL_RELA:2.80055860987;RUNX1..3:2.73121596299;SPI1:2.63976606098;SPIB:2.43342029018;PAX2:2.42596737591;ATF5_CREB3:2.34055939932;ATF4:2.23236494904;CREB1:2.15301038268;ELF1,2,4:1.96887715035;NFIL3:1.93893733008;FOS_FOS{B,L1}_JUN{B,D}:1.81147710931;BACH2:1.70619271693;RXRA_VDR{dimer}:1.70259733751;NANOG{mouse}:1.66221224243;NFATC1..3:1.6517417755;IRF1,2:1.64784583694;CEBPA,B_DDIT3:1.63692845273;MAFB:1.63458823966;HIF1A:1.62569468886;DMAP1_NCOR{1,2}_SMARC:1.59498747829;TGIF1:1.56754446028;FOSL2:1.53896413857;NFE2:1.52358226252;HLF:1.4798992947;JUN:1.41818156055;HMX1:1.40357229981;FOXN1:1.38313315983;FOX{D1,D2}:1.32416163891;T:1.28893187279;FOXO1,3,4:1.18085509366;TLX2:1.17055002923;FOXP3:1.06944152451;BREu{core}:0.97839517259;IRF7:0.953565958123;RORA:0.929059562358;EP300:0.92199758083;EGR1..3:0.80431888194;RFX2..5_RFXANK_RFXAP:0.729258518129;ATF6:0.698081389673;SREBF1,2:0.694272187959;PITX1..3:0.67613037312;BPTF:0.674626800115;NFE2L1:0.671286644759;ATF2:0.662315796579;STAT2,4,6:0.648873726716;IKZF2:0.641999374448;RBPJ:0.36947569922;PAX6:0.3323084541;SMAD1..7,9:0.318918413746;HMGA1,2:0.302278691486;FOX{F1,F2,J1}:0.283813096494;POU2F1..3:0.274685893838;NFE2L2:0.194955904162;NKX2-1,4:0.190067054353;MYFfamily:0.15294435014;SPZ1:0.122104218864;ESR1:0.0664846262652;ZBTB16:0.0112192750968;STAT1,3:0.0106563850168;FOXP1:0.00833502897151;GLI1..3:-0.0128632090486;TBX4,5:-0.0197794971486;MYB:-0.0556764119817;GATA4:-0.0965569434427;PAX8:-0.151425278354;GATA6:-0.180874237687;GCM1,2:-0.189946724384;TFAP4:-0.206372371004;SOX2:-0.215221628084;TOPORS:-0.220783517065;HSF1,2:-0.239923669553;PPARG:-0.252008863433;CDX1,2,4:-0.258621836122;PDX1:-0.26250475337;MTE{core}:-0.281531078078;POU5F1:-0.292134897475;TFCP2:-0.297637993838;ALX4:-0.312323729661;AHR_ARNT_ARNT2:-0.318821793273;PATZ1:-0.339318700086;ZEB1:-0.355102608419;XBP1:-0.37077592685;FOXM1:-0.386660761757;NANOG:-0.396463300576;MZF1:-0.398981751004;HES1:-0.416698536177;MYOD1:-0.425773964595;OCT4_SOX2{dimer}:-0.434311681523;NHLH1,2:-0.444389986374;RREB1:-0.44529927158;TFAP2B:-0.457283379197;MEF2{A,B,C,D}:-0.480854281077;TFDP1:-0.511957478123;MED-1{core}:-0.517865405336;TFAP2{A,C}:-0.528706617518;HNF4A_NR2F1,2:-0.536351502863;ZFP161:-0.547395851396;STAT5{A,B}:-0.563144041473;PAX5:-0.589212311307;NR1H4:-0.594540623394;MTF1:-0.596614783122;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.600510176565;FOXD3:-0.611546232966;SP1:-0.642238521498;HBP1_HMGB_SSRP1_UBTF:-0.650830997838;RXR{A,B,G}:-0.65623744016;HIC1:-0.694065856414;SRF:-0.699016366671;ZNF148:-0.701315399199;SNAI1..3:-0.708026832402;PAX4:-0.709600289554;HOXA9_MEIS1:-0.712718747311;AIRE:-0.713217769336;TAL1_TCF{3,4,12}:-0.713710184034;ZNF384:-0.716131620396;E2F1..5:-0.731296733495;NR5A1,2:-0.737698656501;EN1,2:-0.770507240786;FOXA2:-0.78769090005;FOXL1:-0.795977819437;REST:-0.805823338026;LEF1_TCF7_TCF7L1,2:-0.822069992141;NKX3-1:-0.836052628408;ZNF423:-0.879711998724;PRRX1,2:-0.893665167484;XCPE1{core}:-0.898820670776;CUX2:-0.903466747959;HNF1A:-0.908337611366;PRDM1:-0.913633902268;MAZ:-0.965886445104;CRX:-0.990533167169;NKX6-1,2:-0.998428608123;ESRRA:-1.0242659669;ZNF238:-1.04577366178;IKZF1:-1.05491576758;LMO2:-1.0690125674;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-1.06950003624;HOX{A5,B5}:-1.08592553497;FOXQ1:-1.08877104747;NFY{A,B,C}:-1.09328133579;ELK1,4_GABP{A,B1}:-1.1057410402;VSX1,2:-1.12939938738;SOX5:-1.15960972069;EBF1:-1.19933099326;bHLH_family:-1.20411793646;TBP:-1.21587135418;DBP:-1.22444640524;SOX{8,9,10}:-1.2358527416;NR6A1:-1.26924042405;NRF1:-1.2719835334;RFX1:-1.27915441604;GZF1:-1.31503903606;ZBTB6:-1.3308857103;AR:-1.3706026287;EVI1:-1.40792724549;GTF2I:-1.42597326168;ZIC1..3:-1.48074616721;ADNP_IRX_SIX_ZHX:-1.54166049411;ALX1:-1.60639174452;TLX1..3_NFIC{dimer}:-1.61855078012;GTF2A1,2:-1.62267483073;FOX{I1,J2}:-1.63879074714;NFIX:-1.64298354138;PBX1:-1.66396114964;HOX{A6,A7,B6,B7}:-1.67571376752;ZNF143:-1.67915022011;CDC5L:-1.69304696795;TP53:-1.71995741556;POU6F1:-1.72926972283;NR3C1:-1.74246764834;TEAD1:-1.75541968115;YY1:-1.76834391871;POU3F1..4:-1.80801250495;NKX2-3_NKX2-5:-1.81680469376;UFEwm:-1.87863740851;MYBL2:-1.91757145394;GFI1B:-1.93238198469;NKX2-2,8:-1.96225449219;LHX3,4:-1.96861370164;TEF:-2.02646818626;HAND1,2:-2.0713221971;KLF4:-2.11035762823;SOX17:-2.11106245363;ARID5B:-2.16219560069;NKX3-2:-2.17083933528;GFI1:-2.1818639458;PAX1,9:-2.23088776998;POU1F1:-2.24406424223;ONECUT1,2:-2.3184344461;HOX{A4,D4}:-2.56906730897 | |top_motifs=PAX3,7:3.00618570612;ETS1,2:2.83160872023;NFKB1_REL_RELA:2.80055860987;RUNX1..3:2.73121596299;SPI1:2.63976606098;SPIB:2.43342029018;PAX2:2.42596737591;ATF5_CREB3:2.34055939932;ATF4:2.23236494904;CREB1:2.15301038268;ELF1,2,4:1.96887715035;NFIL3:1.93893733008;FOS_FOS{B,L1}_JUN{B,D}:1.81147710931;BACH2:1.70619271693;RXRA_VDR{dimer}:1.70259733751;NANOG{mouse}:1.66221224243;NFATC1..3:1.6517417755;IRF1,2:1.64784583694;CEBPA,B_DDIT3:1.63692845273;MAFB:1.63458823966;HIF1A:1.62569468886;DMAP1_NCOR{1,2}_SMARC:1.59498747829;TGIF1:1.56754446028;FOSL2:1.53896413857;NFE2:1.52358226252;HLF:1.4798992947;JUN:1.41818156055;HMX1:1.40357229981;FOXN1:1.38313315983;FOX{D1,D2}:1.32416163891;T:1.28893187279;FOXO1,3,4:1.18085509366;TLX2:1.17055002923;FOXP3:1.06944152451;BREu{core}:0.97839517259;IRF7:0.953565958123;RORA:0.929059562358;EP300:0.92199758083;EGR1..3:0.80431888194;RFX2..5_RFXANK_RFXAP:0.729258518129;ATF6:0.698081389673;SREBF1,2:0.694272187959;PITX1..3:0.67613037312;BPTF:0.674626800115;NFE2L1:0.671286644759;ATF2:0.662315796579;STAT2,4,6:0.648873726716;IKZF2:0.641999374448;RBPJ:0.36947569922;PAX6:0.3323084541;SMAD1..7,9:0.318918413746;HMGA1,2:0.302278691486;FOX{F1,F2,J1}:0.283813096494;POU2F1..3:0.274685893838;NFE2L2:0.194955904162;NKX2-1,4:0.190067054353;MYFfamily:0.15294435014;SPZ1:0.122104218864;ESR1:0.0664846262652;ZBTB16:0.0112192750968;STAT1,3:0.0106563850168;FOXP1:0.00833502897151;GLI1..3:-0.0128632090486;TBX4,5:-0.0197794971486;MYB:-0.0556764119817;GATA4:-0.0965569434427;PAX8:-0.151425278354;GATA6:-0.180874237687;GCM1,2:-0.189946724384;TFAP4:-0.206372371004;SOX2:-0.215221628084;TOPORS:-0.220783517065;HSF1,2:-0.239923669553;PPARG:-0.252008863433;CDX1,2,4:-0.258621836122;PDX1:-0.26250475337;MTE{core}:-0.281531078078;POU5F1:-0.292134897475;TFCP2:-0.297637993838;ALX4:-0.312323729661;AHR_ARNT_ARNT2:-0.318821793273;PATZ1:-0.339318700086;ZEB1:-0.355102608419;XBP1:-0.37077592685;FOXM1:-0.386660761757;NANOG:-0.396463300576;MZF1:-0.398981751004;HES1:-0.416698536177;MYOD1:-0.425773964595;OCT4_SOX2{dimer}:-0.434311681523;NHLH1,2:-0.444389986374;RREB1:-0.44529927158;TFAP2B:-0.457283379197;MEF2{A,B,C,D}:-0.480854281077;TFDP1:-0.511957478123;MED-1{core}:-0.517865405336;TFAP2{A,C}:-0.528706617518;HNF4A_NR2F1,2:-0.536351502863;ZFP161:-0.547395851396;STAT5{A,B}:-0.563144041473;PAX5:-0.589212311307;NR1H4:-0.594540623394;MTF1:-0.596614783122;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.600510176565;FOXD3:-0.611546232966;SP1:-0.642238521498;HBP1_HMGB_SSRP1_UBTF:-0.650830997838;RXR{A,B,G}:-0.65623744016;HIC1:-0.694065856414;SRF:-0.699016366671;ZNF148:-0.701315399199;SNAI1..3:-0.708026832402;PAX4:-0.709600289554;HOXA9_MEIS1:-0.712718747311;AIRE:-0.713217769336;TAL1_TCF{3,4,12}:-0.713710184034;ZNF384:-0.716131620396;E2F1..5:-0.731296733495;NR5A1,2:-0.737698656501;EN1,2:-0.770507240786;FOXA2:-0.78769090005;FOXL1:-0.795977819437;REST:-0.805823338026;LEF1_TCF7_TCF7L1,2:-0.822069992141;NKX3-1:-0.836052628408;ZNF423:-0.879711998724;PRRX1,2:-0.893665167484;XCPE1{core}:-0.898820670776;CUX2:-0.903466747959;HNF1A:-0.908337611366;PRDM1:-0.913633902268;MAZ:-0.965886445104;CRX:-0.990533167169;NKX6-1,2:-0.998428608123;ESRRA:-1.0242659669;ZNF238:-1.04577366178;IKZF1:-1.05491576758;LMO2:-1.0690125674;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-1.06950003624;HOX{A5,B5}:-1.08592553497;FOXQ1:-1.08877104747;NFY{A,B,C}:-1.09328133579;ELK1,4_GABP{A,B1}:-1.1057410402;VSX1,2:-1.12939938738;SOX5:-1.15960972069;EBF1:-1.19933099326;bHLH_family:-1.20411793646;TBP:-1.21587135418;DBP:-1.22444640524;SOX{8,9,10}:-1.2358527416;NR6A1:-1.26924042405;NRF1:-1.2719835334;RFX1:-1.27915441604;GZF1:-1.31503903606;ZBTB6:-1.3308857103;AR:-1.3706026287;EVI1:-1.40792724549;GTF2I:-1.42597326168;ZIC1..3:-1.48074616721;ADNP_IRX_SIX_ZHX:-1.54166049411;ALX1:-1.60639174452;TLX1..3_NFIC{dimer}:-1.61855078012;GTF2A1,2:-1.62267483073;FOX{I1,J2}:-1.63879074714;NFIX:-1.64298354138;PBX1:-1.66396114964;HOX{A6,A7,B6,B7}:-1.67571376752;ZNF143:-1.67915022011;CDC5L:-1.69304696795;TP53:-1.71995741556;POU6F1:-1.72926972283;NR3C1:-1.74246764834;TEAD1:-1.75541968115;YY1:-1.76834391871;POU3F1..4:-1.80801250495;NKX2-3_NKX2-5:-1.81680469376;UFEwm:-1.87863740851;MYBL2:-1.91757145394;GFI1B:-1.93238198469;NKX2-2,8:-1.96225449219;LHX3,4:-1.96861370164;TEF:-2.02646818626;HAND1,2:-2.0713221971;KLF4:-2.11035762823;SOX17:-2.11106245363;ARID5B:-2.16219560069;NKX3-2:-2.17083933528;GFI1:-2.1818639458;PAX1,9:-2.23088776998;POU1F1:-2.24406424223;ONECUT1,2:-2.3184344461;HOX{A4,D4}:-2.56906730897 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11388-118C2;search_select_hide=table117:FF:11388-118C2 | |||
}} | }} |
Latest revision as of 17:57, 4 June 2020
Name: | Peripheral Blood Mononuclear Cells, donor3 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs12002 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12002
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12002
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.471 |
10 | 10 | 0.0141 |
100 | 100 | 0.545 |
101 | 101 | 0.796 |
102 | 102 | 0.784 |
103 | 103 | 0.66 |
104 | 104 | 0.503 |
105 | 105 | 0.0937 |
106 | 106 | 5.49434e-4 |
107 | 107 | 0.959 |
108 | 108 | 0.649 |
109 | 109 | 0.26 |
11 | 11 | 0.324 |
110 | 110 | 0.913 |
111 | 111 | 0.12 |
112 | 112 | 0.508 |
113 | 113 | 0.0883 |
114 | 114 | 0.208 |
115 | 115 | 0.307 |
116 | 116 | 0.659 |
117 | 117 | 0.0171 |
118 | 118 | 0.268 |
119 | 119 | 0.624 |
12 | 12 | 0.242 |
120 | 120 | 0.749 |
121 | 121 | 0.374 |
122 | 122 | 0.281 |
123 | 123 | 0.00893 |
124 | 124 | 0.548 |
125 | 125 | 0.531 |
126 | 126 | 0.206 |
127 | 127 | 0.526 |
128 | 128 | 0.0741 |
129 | 129 | 0.886 |
13 | 13 | 0.492 |
130 | 130 | 0.338 |
131 | 131 | 0.679 |
132 | 132 | 0.103 |
133 | 133 | 0.599 |
134 | 134 | 0.809 |
135 | 135 | 0.548 |
136 | 136 | 0.945 |
137 | 137 | 0.00499 |
138 | 138 | 0.211 |
139 | 139 | 0.0359 |
14 | 14 | 0.326 |
140 | 140 | 0.3 |
141 | 141 | 0.615 |
142 | 142 | 0.359 |
143 | 143 | 0.00192 |
144 | 144 | 0.596 |
145 | 145 | 0.664 |
146 | 146 | 0.72 |
147 | 147 | 0.16 |
148 | 148 | 0.066 |
149 | 149 | 0.716 |
15 | 15 | 0.173 |
150 | 150 | 0.686 |
151 | 151 | 0.141 |
152 | 152 | 0.255 |
153 | 153 | 0.665 |
154 | 154 | 0.352 |
155 | 155 | 0.201 |
156 | 156 | 0.77 |
157 | 157 | 0.952 |
158 | 158 | 0.0308 |
159 | 159 | 0.164 |
16 | 16 | 0.982 |
160 | 160 | 0.796 |
161 | 161 | 0.499 |
162 | 162 | 0.0537 |
163 | 163 | 0.346 |
164 | 164 | 0.0632 |
165 | 165 | 0.372 |
166 | 166 | 0.547 |
167 | 167 | 0.319 |
168 | 168 | 0.0126 |
169 | 169 | 0.376 |
17 | 17 | 0.442 |
18 | 18 | 0.349 |
19 | 19 | 0.528 |
2 | 2 | 0.853 |
20 | 20 | 0.465 |
21 | 21 | 0.81 |
22 | 22 | 0.513 |
23 | 23 | 0.129 |
24 | 24 | 0.689 |
25 | 25 | 0.199 |
26 | 26 | 0.382 |
27 | 27 | 0.841 |
28 | 28 | 0.367 |
29 | 29 | 0.123 |
3 | 3 | 0.319 |
30 | 30 | 0.309 |
31 | 31 | 0.931 |
32 | 32 | 0.0195 |
33 | 33 | 0.511 |
34 | 34 | 0.697 |
35 | 35 | 0.0997 |
36 | 36 | 0.26 |
37 | 37 | 0.18 |
38 | 38 | 0.593 |
39 | 39 | 0.941 |
4 | 4 | 0.996 |
40 | 40 | 0.653 |
41 | 41 | 0.00988 |
42 | 42 | 0.372 |
43 | 43 | 0.0493 |
44 | 44 | 0.557 |
45 | 45 | 0.926 |
46 | 46 | 0.411 |
47 | 47 | 0.825 |
48 | 48 | 0.718 |
49 | 49 | 0.14 |
5 | 5 | 0.329 |
50 | 50 | 0.769 |
51 | 51 | 0.478 |
52 | 52 | 0.546 |
53 | 53 | 0.175 |
54 | 54 | 0.592 |
55 | 55 | 0.924 |
56 | 56 | 0.831 |
57 | 57 | 0.892 |
58 | 58 | 0.103 |
59 | 59 | 0.339 |
6 | 6 | 0.92 |
60 | 60 | 0.0903 |
61 | 61 | 0.183 |
62 | 62 | 0.0818 |
63 | 63 | 0.889 |
64 | 64 | 0.464 |
65 | 65 | 0.351 |
66 | 66 | 0.0404 |
67 | 67 | 0.454 |
68 | 68 | 0.208 |
69 | 69 | 0.428 |
7 | 7 | 0.343 |
70 | 70 | 0.13 |
71 | 71 | 0.0908 |
72 | 72 | 0.184 |
73 | 73 | 0.219 |
74 | 74 | 0.225 |
75 | 75 | 0.109 |
76 | 76 | 0.123 |
77 | 77 | 0.805 |
78 | 78 | 0.255 |
79 | 79 | 0.912 |
8 | 8 | 0.752 |
80 | 80 | 0.023 |
81 | 81 | 0.44 |
82 | 82 | 0.175 |
83 | 83 | 0.678 |
84 | 84 | 0.0435 |
85 | 85 | 0.0964 |
86 | 86 | 0.0158 |
87 | 87 | 0.398 |
88 | 88 | 0.712 |
89 | 89 | 0.597 |
9 | 9 | 0.318 |
90 | 90 | 0.203 |
91 | 91 | 0.484 |
92 | 92 | 0.338 |
93 | 93 | 0.753 |
94 | 94 | 0.138 |
95 | 95 | 0.14 |
96 | 96 | 0.712 |
97 | 97 | 0.966 |
98 | 98 | 0.168 |
99 | 99 | 9.43601e-4 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12002
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000135 human peripheral blood mononuclear cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000219 (motile cell)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0000255 (eukaryotic cell)
0000226 (single nucleate cell)
0000080 (circulating cell)
0000842 (mononuclear cell)
UBERON: Anatomy
0000468 (multi-cellular organism)
0000178 (blood)
0004120 (mesoderm-derived structure)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000179 (haemolymphatic fluid)
0000463 (organism substance)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0010317 (germ layer / neural crest derived structure)
0002390 (hematopoietic system)
0004535 (cardiovascular system)
0002193 (hemolymphoid system)
0001009 (circulatory system)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000135 (human peripheral blood mononuclear cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)