FF:11458-119A9: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005619 | ||
|accession_numbers=CAGE;DRX008259;DRR009131;DRZ000556;DRZ001941;DRZ011906;DRZ013291 | |||
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002097,UBERON:0002199,UBERON:0002384,UBERON:0000479,UBERON:0000064,UBERON:0010314,UBERON:0000062,UBERON:0004120,UBERON:0000061,UBERON:0000465,UBERON:0004923,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0003102,UBERON:0010317,UBERON:0002067,UBERON:0002416 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0002320,CL:0002371,CL:0000255,CL:0000057,CL:0002620,CL:0002551 | |||
| | |||
|ancestors_in_anatomy_facet=UBERON: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000057,FF:0000250,FF:0000001,FF:0000062 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr7:19157248..19157268,-!p1@TWIST1!1.79!162.22!TWIST1;;chr1:170633348..170633399,+!p2@PRRX1!1.64!57.87!PRRX1;;chr1:170632285..170632309,+!p1@PRRX1!1.57!40.45!PRRX1;;chr6:34204921..34204939,+!p3@HMGA1!1.54!963.35!HMGA1;;chr12:66218255..66218304,+!p3@HMGA2!1.54!86.94!HMGA2;;chr12:66218598..66218645,+!p2@HMGA2!1.48!131.18!HMGA2;;chr12:54410664..54410684,+!p1@HOXC4,p1@HOXC5,p1@HOXC6!1.43!25.84!HOXC5;;chr1:170633262..170633285,+!p3@PRRX1!1.42!28.93!PRRX1;;chr5:2751762..2751784,-!p1@IRX2!1.39!23.46!IRX2;;chr12:66218183..66218209,+!p4@HMGA2!1.38!43.54!HMGA2;;chr12:66218212..66218244,+!p5@HMGA2!1.37!32.02!HMGA2;;chr19:46801639..46801699,+!p1@HIF3A!1.37!22.33!HIF3A;;chr15:57511609..57511651,+!p2@TCF12!1.33!34.27!TCF12;;chr20:55204351..55204377,+!p1@TFAP2C!1.27!22.33!TFAP2C;;chr2:239756671..239756732,+!p1@TWIST2!1.25!52.81!TWIST2;;chr17:46675558..46675577,-!p2@HOXB6!1.24!16.43!HOXB6;;chr2:239756739..239756755,+!p2@TWIST2!1.23!26.97!TWIST2;;chr2:102091566..102091581,-!p1@RFX8!1.19!14.47!RFX8;;chr6:85474299..85474324,-!p1@TBX18!1.17!24.72!TBX18;;chr2:5832508..5832524,+!p1@SOX11!1.12!12.22!SOX11;;chr12:66218378..66218401,+!p6@HMGA2!1.09!17.42!HMGA2;;chr15:83953397..83953425,-!p1@BNC1!1.07!12.50!BNC1;;chr12:54402745..54402788,+!p1@HOXC8!1.07!10.81!HOXC8;;chr3:147127142..147127168,+!p1@ZIC1!1.03!9.83!ZIC1;;chr18:52969844..52969895,-!p27@TCF4!1.03!9.69!TCF4;;chr2:176994408..176994492,+!p1@HOXD8!1.02!9.55!HOXD8;;chr18:52969674..52969685,-!p24@TCF4!1.00!8.99!TCF4;;chr17:41622765..41622821,-!p2@ETV4!0.99!13.48!ETV4;;chr12:66218573..66218596,+!p7@HMGA2!0.99!13.34!HMGA2;;chr1:170632137..170632172,+!p10@PRRX1!0.97!8.29!PRRX1;;chr20:42543441..42543497,+!p1@TOX2!0.94!35.53!TOX2;;chr2:223163706..223163730,-!p1@PAX3!0.93!7.44!PAX3;;chr5:3595977..3595999,+!p1@IRX1!0.93!7.44!IRX1;;chr2:19558373..19558392,-!p1@OSR1!0.92!20.51!OSR1;;chr2:200322654..200322707,-!p2@SATB2!0.90!10.39!SATB2;;chr5:158526917..158526932,-!p1@EBF1!0.89!17.70!EBF1;;chr17:46675420..46675465,-!p3@HOXB6!0.89!7.87!HOXB6;;chr17:46682321..46682362,-!p1@HOXB6!0.89!6.74!HOXB6;;chr12:66218420..66218439,+!p12@HMGA2!0.89!6.74!HMGA2;;chr1:170632250..170632277,+!p7@PRRX1!0.89!6.74!PRRX1;;chr17:41623009..41623053,-!p4@ETV4!0.88!10.96!ETV4;;chr1:170632477..170632506,+!p6@PRRX1!0.88!6.60!PRRX1;;chrY:21906594..21906622,-!p1@KDM5D!0.88!6.60!KDM5D;;chr12:66218469..66218477,+!p16@HMGA2!0.87!6.46!HMGA2;;chr7:14029283..14029311,-!p1@ETV1!0.86!35.11!ETV1;;chr3:12329358..12329393,+!p3@PPARG!0.86!16.15!PPARG;;chr20:42543506..42543549,+!p2@TOX2!0.86!15.59!TOX2;;chr12:54447637..54447659,+!p4@HOXC4!0.86!6.32!HOXC4;;chr1:54204818..54204870,-!p@chr1:54204818..54204870,-!0.84!6.32!GLIS1;;chr1:170632439..170632465,+!p11@PRRX1!0.84!5.90!PRRX1;;chr12:2986206..2986258,-!p2@FOXM1!0.83!37.22!FOXM1;;chr11:65686802..65686818,+!p6@DRAP1!0.83!10.39!DRAP1;;chr5:2751785..2751808,-!p2@IRX2!0.83!5.76!IRX2;;chr16:86544113..86544145,+!p1@FOXF1!0.82!7.16!FOXF1;;chr11:65686732..65686756,+!p2@DRAP1!0.81!24.86!DRAP1;;chr17:46622205..46622218,-!p3@HOXB2!0.81!6.32!HOXB2;;chr12:66218152..66218174,+!p10@HMGA2!0.81!5.90!HMGA2;;chr2:119605214..119605230,-!p1@EN1!0.81!5.48!EN1;;chr3:157823517..157823562,-!p1@SHOX2!0.80!5.76!SHOX2;;chr17:46671108..46671147,-!p1@HOXB5!0.80!5.34!HOXB5;;chr8:93074803..93074845,-!p1@RUNX1T1!0.80!5.34!RUNX1T1;;chr1:170632723..170632739,+!p8@PRRX1!0.80!5.34!PRRX1;;chr17:46687959..46688007,-!p2@HOXB7!0.79!7.30!HOXB7;;chr12:66218443..66218461,+!p8@HMGA2!0.79!6.74!HMGA2;;chr12:54379029..54379057,+!p2@HOXC10!0.78!5.06!HOXC10;;chr1:170632115..170632136,+!p9@PRRX1!0.78!5.06!PRRX1;;chr10:119303078..119303169,+!p2@EMX2!0.77!4.92!EMX2;;chr3:147111231..147111281,+!p3@ZIC1!0.77!4.92!ZIC1;;chr11:65667846..65667868,-!p1@FOSL1!0.76!139.05!FOSL1;;chr19:42636586..42636607,-!p1@POU2F2!0.76!14.19!POU2F2;;chr17:46667594..46667619,-!p1@HOXB3!0.76!4.78!HOXB3;;chr17:46667628..46667642,-!p2@HOXB3!0.76!4.78!HOXB3;;chr17:41277372..41277418,-!p1@BRCA1!0.75!18.12!BRCA1;;chr17:46622114..46622138,-!p4@HOXB2!0.75!7.44!HOXB2;;chr17:46675539..46675551,-!p7@HOXB6!0.75!4.63!HOXB6;;chr17:46690839..46690884,-!p1@HOXB8!0.75!4.63!HOXB8;;chr12:54422217..54422239,+!p3@HOXC6!0.75!4.63!HOXC6;;chr4:299227..299272,-!p1@ZNF732!0.75!4.63!ZNF732;;chr1:47779762..47779827,-!p1@STIL,p1@TAL1!0.74!22.61!TAL1;;chr5:321810..321877,+!p1@AHRR!0.74!15.59!AHRR;;chr17:46688334..46688385,-!p1@HOXB7!0.74!6.74!HOXB7;;chr17:46675586..46675600,-!p6@HOXB6!0.74!4.49!HOXB6;;chr4:4861385..4861398,+!p1@MSX1!0.73!14.19!MSX1;;chr3:12329397..12329433,+!p2@PPARG!0.73!10.81!PPARG;;chr12:54378923..54378966,+!p1@HOXC10!0.73!4.35!HOXC10;;chr17:41623692..41623715,-!p1@ETV4!0.72!20.22!ETV4;;chr12:66358080..66358094,+!p15@HMGA2!0.72!4.21!HMGA2;;chr19:22817119..22817145,+!p1@ZNF492!0.71!7.30!ZNF492;;chr5:3595961..3595975,+!p3@IRX1!0.71!4.07!IRX1;;chr12:96588143..96588185,+!p1@ELK3!0.70!55.90!ELK3;;chr6:31126291..31126399,+!p1@TCF19!0.70!43.40!TCF19;;chr5:72744594..72744609,-!p1@FOXD1!0.70!20.79!FOXD1;;chr17:46622070..46622109,-!p1@HOXB2!0.70!9.83!HOXB2;;chr11:46299539..46299620,+!p2@CREB3L1!0.70!7.30!CREB3L1;;chr3:141121847..141121868,+!p5@ZBTB38!0.69!6.32!ZBTB38;;chr12:54447599..54447630,+!p3@HOXC4!0.69!4.92!HOXC4;;chr4:174450089..174450153,-!p2@HAND2!0.69!3.93!HAND2;;chr5:3595934..3595957,+!p2@IRX1!0.69!3.93!IRX1;;chr16:86612320..86612394,+!p1@FOXL1!0.69!3.93!FOXL1;;chr11:46299199..46299233,+!p1@CREB3L1!0.68!22.05!CREB3L1;;chr6:45390025..45390076,+!p2@RUNX2!0.68!10.11!RUNX2;;chr6:85473156..85473210,-!p2@TBX18!0.68!4.78!TBX18;;chr7:27205106..27205134,-!p2@HOXA9!0.68!3.79!HOXA9;;chr12:54380404..54380433,+!p3@HOXC10!0.68!3.79!HOXC10;;chr12:54393880..54393962,+!p1@HOXC9!0.68!3.79!HOXC9;;chr12:54402790..54402805,+!p2@HOXC8!0.68!3.79!HOXC8;;chr12:54410639..54410659,+!p2@HOXC4,p2@HOXC5,p2@HOXC6!0.68!3.79!HOXC5;;chr8:49833978..49833996,-!p1@SNAI2!0.67!87.92!SNAI2;;chr1:170632959..170632987,+!p4@PRRX1!0.67!4.07!PRRX1;;chr4:174451370..174451387,-!p1@HAND2!0.67!3.65!HAND2;;chr6:34204672..34204692,+!p1@HMGA1!0.65!464.61!HMGA1;;chr12:66218836..66218888,+!p1@HMGA2!0.65!38.06!HMGA2;;chr8:49833948..49833973,-!p2@SNAI2!0.65!25.28!SNAI2;;chr9:132427972..132428056,+!p1@PRRX2!0.65!4.78!PRRX2;;chr8:93074848..93074871,-!p3@RUNX1T1!0.65!3.51!RUNX1T1;;chrY:2803415..2803468,+!p1@ZFY!0.64!3.37!ZFY;;chr2:119604456..119604501,-!p2@EN1!0.64!3.37!EN1;;chr3:157824001..157824078,-!p2@SHOX2!0.64!3.37!SHOX2;;chr17:59477233..59477263,+!p1@TBX2!0.63!11.66!TBX2;;chr7:42276787..42276815,-!p1@GLI3!0.63!9.97!GLI3;;chr7:27205136..27205164,-!p1@HOXA9!0.63!3.23!HOXA9;;chr17:41622731..41622764,-!p5@ETV4!0.63!3.23!ETV4;;chr2:102091144..102091183,-!p2@RFX8!0.63!3.23!RFX8;;chr2:102091478..102091490,-!p3@RFX8!0.63!3.23!RFX8;;chr20:32274179..32274213,-!p1@E2F1!0.61!24.02!E2F1;;chr6:85474198..85474212,-!p3@TBX18!0.61!3.09!TBX18;;chr12:54447686..54447704,+!p5@HOXC4!0.61!3.09!HOXC4;;chr19:38720294..38720348,-!p1@DPF1!0.60!3.93!DPF1;;chr17:46622440..46622477,-!p5@HOXB2!0.60!3.37!HOXB2;;chr2:102091590..102091601,-!p5@RFX8!0.60!2.95!RFX8;;chr5:138609782..138609826,+!p5@MATR3!0.59!22.61!MATR3;;chr16:86600426..86600441,+!p1@FOXC2!0.59!8.15!FOXC2;;chr1:8926441..8926473,-!p10@ENO1!0.59!4.78!ENO1;;chr17:46655704..46655718,-!p2@HOXB4!0.59!4.63!HOXB4;;chr12:115121962..115121987,-!p1@TBX3!0.58!28.79!TBX3;;chr14:55493763..55493824,-!p1@WDHD1!0.58!25.70!WDHD1;;chr6:45390077..45390105,+!p9@RUNX2!0.58!3.79!RUNX2;;chr3:12329320..12329338,+!p4@PPARG!0.58!3.09!PPARG;;chr12:54402729..54402743,+!p3@HOXC8!0.58!2.81!HOXC8;;chr17:46655672..46655697,-!p3@HOXB4!0.58!2.81!HOXB4;;chr5:158527139..158527161,-!p5@EBF1!0.58!2.81!EBF1;;chr8:25902876..25902936,-!p1@EBF2!0.58!2.81!EBF2;;chr8:93074872..93074884,-!p10@RUNX1T1!0.58!2.81!RUNX1T1;;chr6:34204973..34204990,+!p4@HMGA1!0.57!45.08!HMGA1;;chr21:47063625..47063658,+!p1@PCBP3!0.57!14.19!PCBP3;;chr7:19157043..19157088,-!p2@TWIST1!0.57!8.01!TWIST1;;chr2:169312600..169312606,+!p2@CERS6!0.57!4.63!CERS6;;chr12:66218003..66218018,+!p9@HMGA2!0.57!3.51!HMGA2;;chr3:21792585..21792625,-!p2@ZNF385D!0.57!3.09!ZNF385D;;chr17:41623667..41623682,-!p8@ETV4!0.57!2.95!ETV4;;chr16:54320675..54320715,-!p1@IRX3!0.56!6.46!IRX3;;chr17:46622229..46622257,-!p6@HOXB2!0.56!3.23!HOXB2;;chr17:46691732..46691766,-!p4@HOXB8!0.56!2.67!HOXB8;;chr3:21792631..21792665,-!p3@ZNF385D!0.56!2.67!ZNF385D;;chr20:42295745..42295765,+!p1@MYBL2!0.55!52.25!MYBL2;;chr9:4300050..4300118,-!p1@GLIS3!0.55!20.51!GLIS3;;chr1:8934931..8934947,-!p4@ENO1!0.55!9.97!ENO1;;chr7:42276822..42276895,-!p2@GLI3!0.55!8.99!GLI3;;chr4:26322267..26322334,+!p3@RBPJ!0.55!7.16!RBPJ;;chr2:200323414..200323455,-!p1@SATB2!0.55!6.32!SATB2;;chr2:175199675..175199688,+!p1@SP9!0.55!2.53!SP9;;chr3:147127177..147127194,+!p2@ZIC1!0.55!2.53!ZIC1;;chr5:158527104..158527135,-!p4@EBF1!0.55!2.53!EBF1;;chr6:85473227..85473243,-!p5@TBX18!0.55!2.53!TBX18;;chr1:170633058..170633084,+!p5@PRRX1!0.55!2.53!PRRX1;;chr20:42295713..42295738,+!p2@MYBL2!0.54!17.98!MYBL2;;chr4:206390..206444,+!p1@ZNF876P!0.54!5.06!ZNF876P;;chr19:23299814..23299844,+!p1@ZNF730!0.54!3.23!ZNF730;;chr7:44143925..44143970,+!p1@AEBP1!0.53!68.26!AEBP1;;chr12:77459306..77459365,-!p1@E2F7!0.53!38.34!E2F7;;chr4:1873100..1873152,+!p1@WHSC1!0.53!23.31!WHSC1;;chr17:41622925..41622976,-!p3@ETV4!0.53!3.93!ETV4;;chr4:109089095..109089144,-!p6@LEF1!0.53!2.39!LEF1;;chr1:119530493..119530572,-!p1@TBX15!0.53!2.39!TBX15;;chr1:170632647..170632659,+!p17@PRRX1!0.53!2.39!PRRX1;;chr5:176738887..176738934,-!p1@MXD3!0.52!19.52!MXD3;;chr10:114710244..114710257,+!p3@TCF7L2!0.52!7.58!TCF7L2;;chr7:44143978..44143989,+!p2@AEBP1!0.52!4.92!AEBP1;;chr2:185463247..185463263,+!p1@ZNF804A!0.52!4.63!ZNF804A;;chr8:128748308..128748324,+!p2@MYC!0.51!82.16!MYC;;chr12:2986275..2986363,-!p1@FOXM1!0.51!29.35!FOXM1;;chr1:247171347..247171366,-!p2@ZNF695!0.51!4.78!ZNF695;;chr15:57210759..57210775,+!p7@TCF12!0.51!3.65!TCF12;;chr3:147111198..147111225,+!p4@ZIC1!0.51!2.25!ZIC1;;chr4:111558135..111558198,-!p2@PITX2!0.51!2.25!PITX2;;chr10:119302232..119302265,+!p1@EMX2!0.51!2.25!EMX2;;chr12:54410948..54410992,+!p3@HOXC5!0.51!2.25!HOXC5;;ch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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000057;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0002551;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0002620;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002067;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002097;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002416 | |||
|ffid_belonging_in_development=CL:0000134 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Dermal%252c%2520donor6.CNhs12059.11458-119A9.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Dermal%252c%2520donor6.CNhs12059.11458-119A9.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Dermal%252c%2520donor6.CNhs12059.11458-119A9.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Dermal%252c%2520donor6.CNhs12059.11458-119A9.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Dermal%252c%2520donor6.CNhs12059.11458-119A9.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11458-119A9 | |||
|is_a=EFO:0002091;;FF:0000062 | |||
|is_obsolete= | |||
|library_id=CNhs12059 | |||
|library_id_phase_based=2:CNhs12059 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11458 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11458 | |||
|name=Fibroblast - Dermal, donor6 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs12059,LSID838,release011,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=119 | |||
|rna_catalog_number=SC2305 | |||
|rna_concentration=0.64 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-isopropanol-v1.0 | |||
|rna_lot_number=4828 | |||
|rna_od260/230= | |||
|rna_od260/280= | |||
|rna_position=A9 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=119A9 | |||
|rna_weight_ug=10 | |||
|sample_age=fetal | |||
|sample_category=primary cells | |||
|sample_cell_catalog=N/A | |||
|sample_cell_line= | |||
|sample_cell_lot=N/A | |||
|sample_cell_type=fibroblast | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=Sciencell/3H | |||
|sample_description= | |||
|sample_dev_stage=fetus | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.13386606867131e-281!GO:0043226;organelle;2.5023470823282e-231!GO:0043229;intracellular organelle;6.87427090900436e-231!GO:0043231;intracellular membrane-bound organelle;1.89247533117687e-227!GO:0043227;membrane-bound organelle;2.07910576956561e-227!GO:0005737;cytoplasm;2.18451784183171e-184!GO:0044422;organelle part;8.46256601403792e-171!GO:0044446;intracellular organelle part;5.07802140978699e-169!GO:0044444;cytoplasmic part;6.2058796628442e-127!GO:0032991;macromolecular complex;8.04594640958767e-120!GO:0044237;cellular metabolic process;3.84561721172461e-109!GO:0005634;nucleus;4.20853465041762e-109!GO:0044238;primary metabolic process;1.80528755520667e-108!GO:0030529;ribonucleoprotein complex;7.96925784511912e-104!GO:0043170;macromolecule metabolic process;6.16474701176828e-101!GO:0044428;nuclear part;4.25858140042027e-91!GO:0043233;organelle lumen;2.60228244186138e-86!GO:0031974;membrane-enclosed lumen;2.60228244186138e-86!GO:0003723;RNA binding;2.19683408465416e-82!GO:0005739;mitochondrion;2.40486035449566e-74!GO:0005515;protein binding;6.17521268547662e-69!GO:0043283;biopolymer metabolic process;1.98636679563128e-62!GO:0005840;ribosome;8.18283972375703e-62!GO:0006396;RNA processing;3.79517786979449e-61!GO:0043234;protein complex;5.45903177823884e-60!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.5562732603738e-59!GO:0006412;translation;9.69181278361566e-56!GO:0010467;gene expression;1.92792719771733e-55!GO:0003735;structural constituent of ribosome;2.3090937324586e-54!GO:0016043;cellular component organization and biogenesis;6.991524510079e-53!GO:0031981;nuclear lumen;7.97291512688771e-53!GO:0044429;mitochondrial part;1.07822634592827e-50!GO:0031090;organelle membrane;5.32766861423278e-50!GO:0019538;protein metabolic process;1.62878728088948e-48!GO:0043228;non-membrane-bound organelle;1.42521354111873e-47!GO:0043232;intracellular non-membrane-bound organelle;1.42521354111873e-47!GO:0031967;organelle envelope;2.20406096492266e-47!GO:0031975;envelope;6.13732584816287e-47!GO:0033279;ribosomal subunit;3.11132212419294e-46!GO:0009058;biosynthetic process;5.70649725013444e-46!GO:0016071;mRNA metabolic process;5.03373011377169e-45!GO:0006259;DNA metabolic process;1.00414729541334e-43!GO:0044249;cellular biosynthetic process;1.52429950982736e-43!GO:0044260;cellular macromolecule metabolic process;3.30635334171608e-43!GO:0044267;cellular protein metabolic process;5.4606556940896e-43!GO:0006996;organelle organization and biogenesis;1.61352698805393e-42!GO:0008380;RNA splicing;4.16763479962039e-42!GO:0015031;protein transport;4.65905665479282e-42!GO:0033036;macromolecule localization;1.01668540619325e-41!GO:0005829;cytosol;1.17280952423164e-41!GO:0009059;macromolecule biosynthetic process;2.81070811325967e-41!GO:0006397;mRNA processing;4.22080371069802e-39!GO:0003676;nucleic acid binding;5.81063057721902e-39!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.28789945905392e-38!GO:0045184;establishment of protein localization;3.28521634742895e-38!GO:0008104;protein localization;8.64213150862751e-38!GO:0065003;macromolecular complex assembly;2.2689022990878e-36!GO:0046907;intracellular transport;2.90805110270079e-36!GO:0007049;cell cycle;4.97683042943957e-34!GO:0005830;cytosolic ribosome (sensu Eukaryota);6.30548933212174e-33!GO:0022607;cellular component assembly;1.69052513792993e-32!GO:0005654;nucleoplasm;4.13667441442404e-32!GO:0005740;mitochondrial envelope;1.44916843558317e-31!GO:0005681;spliceosome;6.11620385832164e-30!GO:0006886;intracellular protein transport;6.86648303611101e-30!GO:0031966;mitochondrial membrane;2.33350976469447e-29!GO:0000166;nucleotide binding;3.83466695027293e-29!GO:0019866;organelle inner membrane;2.70198099264745e-28!GO:0000278;mitotic cell cycle;7.98520605134466e-28!GO:0022402;cell cycle process;1.0724486209618e-26!GO:0016070;RNA metabolic process;1.98092422486099e-26!GO:0006974;response to DNA damage stimulus;3.09221353616901e-26!GO:0005694;chromosome;3.17620284880414e-26!GO:0005743;mitochondrial inner membrane;4.45970816428905e-26!GO:0044445;cytosolic part;4.90145514932723e-26!GO:0044451;nucleoplasm part;1.44502522671917e-25!GO:0015934;large ribosomal subunit;1.00823000692473e-23!GO:0044427;chromosomal part;1.11127911632986e-23!GO:0015935;small ribosomal subunit;1.23223430065307e-23!GO:0022403;cell cycle phase;1.90964876032927e-23!GO:0016462;pyrophosphatase activity;4.11124302705914e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;5.33158690330771e-23!GO:0031980;mitochondrial lumen;6.48117937184363e-23!GO:0005759;mitochondrial matrix;6.48117937184363e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;9.21759597639154e-23!GO:0000087;M phase of mitotic cell cycle;1.01380226770952e-22!GO:0006119;oxidative phosphorylation;1.02868470470878e-22!GO:0051649;establishment of cellular localization;1.55658311555828e-22!GO:0006281;DNA repair;1.70321136671042e-22!GO:0051641;cellular localization;2.15534052885243e-22!GO:0017111;nucleoside-triphosphatase activity;2.17061019032459e-22!GO:0007067;mitosis;2.97130799390916e-22!GO:0005730;nucleolus;1.29285619877989e-21!GO:0044455;mitochondrial membrane part;2.07259817907507e-21!GO:0012505;endomembrane system;2.63069771309379e-21!GO:0006457;protein folding;1.31264773580828e-20!GO:0051301;cell division;1.70785382440313e-20!GO:0022618;protein-RNA complex assembly;3.05602677577941e-20!GO:0017076;purine nucleotide binding;4.99241586438182e-20!GO:0032553;ribonucleotide binding;5.74568370926978e-20!GO:0032555;purine ribonucleotide binding;5.74568370926978e-20!GO:0000279;M phase;7.17404643847297e-20!GO:0016874;ligase activity;1.49916351019516e-19!GO:0051276;chromosome organization and biogenesis;2.29784661341552e-19!GO:0006260;DNA replication;3.38986280880167e-19!GO:0042254;ribosome biogenesis and assembly;5.49577128571716e-19!GO:0009719;response to endogenous stimulus;1.30014820332403e-18!GO:0005524;ATP binding;3.04276245379435e-18!GO:0006512;ubiquitin cycle;3.74778013292659e-18!GO:0005761;mitochondrial ribosome;8.10925402380153e-18!GO:0000313;organellar ribosome;8.10925402380153e-18!GO:0048770;pigment granule;9.37289457159787e-18!GO:0042470;melanosome;9.37289457159787e-18!GO:0005746;mitochondrial respiratory chain;1.07169658854348e-17!GO:0032559;adenyl ribonucleotide binding;1.09647010434863e-17!GO:0008135;translation factor activity, nucleic acid binding;1.19804163171118e-17!GO:0030554;adenyl nucleotide binding;1.45633230908955e-17!GO:0044265;cellular macromolecule catabolic process;3.36191282262772e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;4.14707966559753e-17!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);8.67625729606976e-17!GO:0043285;biopolymer catabolic process;9.54359505423633e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;1.02161237810747e-16!GO:0006511;ubiquitin-dependent protein catabolic process;1.57737119181192e-16!GO:0019941;modification-dependent protein catabolic process;1.63583468964989e-16!GO:0043632;modification-dependent macromolecule catabolic process;1.63583468964989e-16!GO:0005635;nuclear envelope;1.81145856139968e-16!GO:0051186;cofactor metabolic process;2.38011298204323e-16!GO:0044257;cellular protein catabolic process;2.99698896296059e-16!GO:0000398;nuclear mRNA splicing, via spliceosome;3.05540063415496e-16!GO:0000375;RNA splicing, via transesterification reactions;3.05540063415496e-16!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;3.05540063415496e-16!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);3.30042709703105e-16!GO:0050136;NADH dehydrogenase (quinone) activity;4.31631355767866e-16!GO:0003954;NADH dehydrogenase activity;4.31631355767866e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;4.31631355767866e-16!GO:0000502;proteasome complex (sensu Eukaryota);7.21575505093681e-16!GO:0005783;endoplasmic reticulum;7.9376149128368e-16!GO:0044453;nuclear membrane part;1.28333214386308e-15!GO:0031965;nuclear membrane;1.97353833497398e-15!GO:0009057;macromolecule catabolic process;2.03905363852548e-15!GO:0006605;protein targeting;2.75343260472236e-15!GO:0042775;organelle ATP synthesis coupled electron transport;1.698690495174e-14!GO:0042773;ATP synthesis coupled electron transport;1.698690495174e-14!GO:0006325;establishment and/or maintenance of chromatin architecture;2.14530192663149e-14!GO:0030163;protein catabolic process;2.19035154173246e-14!GO:0030964;NADH dehydrogenase complex (quinone);3.01548406458632e-14!GO:0045271;respiratory chain complex I;3.01548406458632e-14!GO:0005747;mitochondrial respiratory chain complex I;3.01548406458632e-14!GO:0044432;endoplasmic reticulum part;4.00273965052527e-14!GO:0048193;Golgi vesicle transport;5.69624462543399e-14!GO:0003743;translation initiation factor activity;6.43664245380486e-14!GO:0044248;cellular catabolic process;7.32080637462646e-14!GO:0006323;DNA packaging;7.99954024886636e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;8.18594859848988e-14!GO:0008134;transcription factor binding;1.08073223897545e-13!GO:0051082;unfolded protein binding;1.31475811398259e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.80984291928457e-13!GO:0006399;tRNA metabolic process;1.92193024188262e-13!GO:0043412;biopolymer modification;2.68652668698732e-13!GO:0005643;nuclear pore;4.0292336490968e-13!GO:0005794;Golgi apparatus;4.9305417221352e-13!GO:0006413;translational initiation;7.48753218748976e-13!GO:0004386;helicase activity;7.84270761024055e-13!GO:0016887;ATPase activity;8.55265153794107e-13!GO:0006364;rRNA processing;9.43903007979152e-13!GO:0042623;ATPase activity, coupled;1.01518136383321e-12!GO:0016604;nuclear body;1.12773040794278e-12!GO:0006732;coenzyme metabolic process;1.6605162232693e-12!GO:0016072;rRNA metabolic process;3.93999269626309e-12!GO:0065004;protein-DNA complex assembly;6.10809921188561e-12!GO:0000785;chromatin;6.16586583466482e-12!GO:0051726;regulation of cell cycle;1.30886786659881e-11!GO:0015630;microtubule cytoskeleton;1.32370314012979e-11!GO:0000074;regulation of progression through cell cycle;1.3264347018271e-11!GO:0065002;intracellular protein transport across a membrane;1.36916218580317e-11!GO:0006464;protein modification process;1.83796453201938e-11!GO:0006913;nucleocytoplasmic transport;1.94442958927443e-11!GO:0005793;ER-Golgi intermediate compartment;2.17678568864101e-11!GO:0009055;electron carrier activity;2.31520289437549e-11!GO:0009259;ribonucleotide metabolic process;2.40939318134274e-11!GO:0006333;chromatin assembly or disassembly;2.47370443838846e-11!GO:0050657;nucleic acid transport;2.89012120044968e-11!GO:0051236;establishment of RNA localization;2.89012120044968e-11!GO:0050658;RNA transport;2.89012120044968e-11!GO:0046930;pore complex;3.43482318334115e-11!GO:0006403;RNA localization;3.75343060063477e-11!GO:0051169;nuclear transport;4.64298838534707e-11!GO:0000775;chromosome, pericentric region;8.06520581800677e-11!GO:0008026;ATP-dependent helicase activity;8.24000531249742e-11!GO:0006163;purine nucleotide metabolic process;8.84576403608239e-11!GO:0006446;regulation of translational initiation;1.0655822885523e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;2.66197236773904e-10!GO:0009150;purine ribonucleotide metabolic process;4.81780450771557e-10!GO:0008565;protein transporter activity;4.85624698137369e-10!GO:0043687;post-translational protein modification;4.85946424932942e-10!GO:0016607;nuclear speck;5.5768608308597e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;6.50731355738173e-10!GO:0004812;aminoacyl-tRNA ligase activity;6.50731355738173e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;6.50731355738173e-10!GO:0008639;small protein conjugating enzyme activity;7.22762023424587e-10!GO:0009260;ribonucleotide biosynthetic process;7.7995426782572e-10!GO:0030532;small nuclear ribonucleoprotein complex;8.28796861172847e-10!GO:0005789;endoplasmic reticulum membrane;8.37965778306299e-10!GO:0006164;purine nucleotide biosynthetic process;9.48592017291091e-10!GO:0016192;vesicle-mediated transport;1.34160702242835e-09!GO:0005819;spindle;1.38831928007744e-09!GO:0003697;single-stranded DNA binding;1.45883528335298e-09!GO:0043038;amino acid activation;1.57594626295709e-09!GO:0006418;tRNA aminoacylation for protein translation;1.57594626295709e-09!GO:0043039;tRNA aminoacylation;1.57594626295709e-09!GO:0051028;mRNA transport;1.63854840102784e-09!GO:0006261;DNA-dependent DNA replication;1.72126698736719e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.8107091796935e-09!GO:0004842;ubiquitin-protein ligase activity;1.8140104594505e-09!GO:0006334;nucleosome assembly;2.01339242515986e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;3.02795979473435e-09!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;3.12383190064979e-09!GO:0009060;aerobic respiration;3.33417943675697e-09!GO:0006461;protein complex assembly;3.33507664294799e-09!GO:0043566;structure-specific DNA binding;3.36938979605854e-09!GO:0016779;nucleotidyltransferase activity;3.56834911072718e-09!GO:0009152;purine ribonucleotide biosynthetic process;4.93353686486867e-09!GO:0019787;small conjugating protein ligase activity;5.15660806083569e-09!GO:0009199;ribonucleoside triphosphate metabolic process;5.53318529227527e-09!GO:0050794;regulation of cellular process;5.68906808582303e-09!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;6.28469416759072e-09!GO:0031497;chromatin assembly;6.59028658739093e-09!GO:0009141;nucleoside triphosphate metabolic process;6.77799414077857e-09!GO:0005813;centrosome;6.98124286613643e-09!GO:0003712;transcription cofactor activity;7.57647874279716e-09!GO:0006888;ER to Golgi vesicle-mediated transport;8.58263629767835e-09!GO:0016740;transferase activity;8.89342906180364e-09!GO:0017038;protein import;1.11941217231284e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.30020285875114e-08!GO:0009144;purine nucleoside triphosphate metabolic process;1.30020285875114e-08!GO:0045333;cellular respiration;1.54882555970779e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.7056841742759e-08!GO:0051188;cofactor biosynthetic process;2.04800101124416e-08!GO:0005815;microtubule organizing center;2.15308750422916e-08!GO:0051329;interphase of mitotic cell cycle;3.64974256335022e-08!GO:0006366;transcription from RNA polymerase II promoter;4.14010286450824e-08!GO:0016881;acid-amino acid ligase activity;5.83761967471268e-08!GO:0006099;tricarboxylic acid cycle;6.05618702688969e-08!GO:0046356;acetyl-CoA catabolic process;6.05618702688969e-08!GO:0009056;catabolic process;6.23139972682089e-08!GO:0030120;vesicle coat;6.7496693413337e-08!GO:0030662;coated vesicle membrane;6.7496693413337e-08!GO:0005657;replication fork;7.5887608240078e-08!GO:0046034;ATP metabolic process;7.95726350989349e-08!GO:0005667;transcription factor complex;8.98151637723725e-08!GO:0051325;interphase;9.38662974351876e-08!GO:0003899;DNA-directed RNA polymerase activity;9.72470920908163e-08!GO:0009142;nucleoside triphosphate biosynthetic process;1.0327076200743e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.0327076200743e-07!GO:0015986;ATP synthesis coupled proton transport;1.0327076200743e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.0327076200743e-07!GO:0007051;spindle organization and biogenesis;1.03719980665774e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.2225408587328e-07!GO:0007005;mitochondrion organization and biogenesis;1.4319081531087e-07!GO:0006084;acetyl-CoA metabolic process;1.51834362061933e-07!GO:0009117;nucleotide metabolic process;1.64092333015162e-07!GO:0009109;coenzyme catabolic process;1.83121856658567e-07!GO:0016568;chromatin modification;1.98207468895678e-07!GO:0008094;DNA-dependent ATPase activity;2.17251395454259e-07!GO:0012501;programmed cell death;2.30436770376997e-07!GO:0019829;cation-transporting ATPase activity;2.46578992482327e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.47086351542866e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.47086351542866e-07!GO:0051187;cofactor catabolic process;3.37067325888041e-07!GO:0048475;coated membrane;3.44214561504024e-07!GO:0030117;membrane coat;3.44214561504024e-07!GO:0006915;apoptosis;3.48038374326756e-07!GO:0000075;cell cycle checkpoint;4.10388473293105e-07!GO:0000245;spliceosome assembly;4.19284019529411e-07!GO:0015078;hydrogen ion transmembrane transporter activity;4.19284019529411e-07!GO:0003924;GTPase activity;6.69106619826966e-07!GO:0016469;proton-transporting two-sector ATPase complex;7.34269038390998e-07!GO:0005762;mitochondrial large ribosomal subunit;7.49246970395863e-07!GO:0000315;organellar large ribosomal subunit;7.49246970395863e-07!GO:0032446;protein modification by small protein conjugation;8.54455965642837e-07!GO:0016567;protein ubiquitination;1.32460313226822e-06!GO:0006754;ATP biosynthetic process;1.4305002092226e-06!GO:0006753;nucleoside phosphate metabolic process;1.4305002092226e-06!GO:0045259;proton-transporting ATP synthase complex;1.44708066729943e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.47786669512057e-06!GO:0019222;regulation of metabolic process;1.48036152144349e-06!GO:0000151;ubiquitin ligase complex;1.56624760683377e-06!GO:0009108;coenzyme biosynthetic process;1.57754752364694e-06!GO:0005788;endoplasmic reticulum lumen;1.64668913877912e-06!GO:0044431;Golgi apparatus part;2.05053558149318e-06!GO:0043623;cellular protein complex assembly;2.07804034996395e-06!GO:0016853;isomerase activity;2.09970513986579e-06!GO:0008219;cell death;2.26298030524172e-06!GO:0016265;death;2.26298030524172e-06!GO:0016491;oxidoreductase activity;2.69600658575877e-06!GO:0006752;group transfer coenzyme metabolic process;2.95078854847892e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;3.16286815657186e-06!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;3.23572983729575e-06!GO:0008654;phospholipid biosynthetic process;4.05786592448668e-06!GO:0051170;nuclear import;4.23545983971523e-06!GO:0048523;negative regulation of cellular process;4.60582716636211e-06!GO:0005768;endosome;4.85906211440199e-06!GO:0005798;Golgi-associated vesicle;5.85462403120258e-06!GO:0016859;cis-trans isomerase activity;5.90966016174398e-06!GO:0019843;rRNA binding;6.36202364373153e-06!GO:0006613;cotranslational protein targeting to membrane;6.71574718996903e-06!GO:0006302;double-strand break repair;6.77952803849321e-06!GO:0005839;proteasome core complex (sensu Eukaryota);7.15057882259165e-06!GO:0051246;regulation of protein metabolic process;7.37942429083604e-06!GO:0006606;protein import into nucleus;8.0690130070885e-06!GO:0003724;RNA helicase activity;8.14143293533335e-06!GO:0006793;phosphorus metabolic process;8.48741975844557e-06!GO:0006796;phosphate metabolic process;8.48741975844557e-06!GO:0000314;organellar small ribosomal subunit;9.45122862274572e-06!GO:0005763;mitochondrial small ribosomal subunit;9.45122862274572e-06!GO:0007059;chromosome segregation;1.15945314449407e-05!GO:0016787;hydrolase activity;1.34905892285145e-05!GO:0007010;cytoskeleton organization and biogenesis;1.35981491798032e-05!GO:0000776;kinetochore;1.57250522136677e-05!GO:0031252;leading edge;2.07692943377257e-05!GO:0050789;regulation of biological process;2.36992220956184e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.37353145209575e-05!GO:0008033;tRNA processing;2.37641610643393e-05!GO:0006091;generation of precursor metabolites and energy;2.37641610643393e-05!GO:0016126;sterol biosynthetic process;2.54837692931364e-05!GO:0006310;DNA recombination;2.61475003360689e-05!GO:0005525;GTP binding;2.66890304799383e-05!GO:0044440;endosomal part;2.70736388904274e-05!GO:0010008;endosome membrane;2.70736388904274e-05!GO:0043021;ribonucleoprotein binding;3.17218175578091e-05!GO:0004298;threonine endopeptidase activity;3.34523940495168e-05!GO:0003684;damaged DNA binding;3.46013206314716e-05!GO:0016563;transcription activator activity;3.77793618394375e-05!GO:0031324;negative regulation of cellular metabolic process;4.08856036708619e-05!GO:0044452;nucleolar part;4.12799906768752e-05!GO:0003713;transcription coactivator activity;4.14021351254314e-05!GO:0000786;nucleosome;4.61098815897041e-05!GO:0045454;cell redox homeostasis;4.64663670150325e-05!GO:0000139;Golgi membrane;4.76886076117915e-05!GO:0016741;transferase activity, transferring one-carbon groups;5.45302605672408e-05!GO:0051427;hormone receptor binding;5.58933559295702e-05!GO:0016310;phosphorylation;5.71390690331341e-05!GO:0008168;methyltransferase activity;5.87830934646181e-05!GO:0015980;energy derivation by oxidation of organic compounds;5.95836568597906e-05!GO:0016363;nuclear matrix;6.43271513696763e-05!GO:0030867;rough endoplasmic reticulum membrane;6.54195041339573e-05!GO:0000059;protein import into nucleus, docking;7.69832484864059e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;8.01468753707204e-05!GO:0031968;organelle outer membrane;8.33896461708768e-05!GO:0006383;transcription from RNA polymerase III promoter;8.39230714214432e-05!GO:0003682;chromatin binding;8.77869131147611e-05!GO:0051052;regulation of DNA metabolic process;8.90390353147242e-05!GO:0051168;nuclear export;9.14168606655336e-05!GO:0005769;early endosome;9.35615037646875e-05!GO:0048519;negative regulation of biological process;9.45965419194523e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;9.46614440363799e-05!GO:0019867;outer membrane;0.000104543690104677!GO:0035257;nuclear hormone receptor binding;0.000121087162911077!GO:0006626;protein targeting to mitochondrion;0.000123275740402591!GO:0031323;regulation of cellular metabolic process;0.000123305392257456!GO:0007088;regulation of mitosis;0.000128890781217775!GO:0031988;membrane-bound vesicle;0.000128931379853373!GO:0009165;nucleotide biosynthetic process;0.000145260331841724!GO:0006916;anti-apoptosis;0.000149095226867062!GO:0003690;double-stranded DNA binding;0.000150219484374204!GO:0045786;negative regulation of progression through cell cycle;0.000150802178284337!GO:0003678;DNA helicase activity;0.000158325688190806!GO:0005874;microtubule;0.000166384652682122!GO:0007093;mitotic cell cycle checkpoint;0.000166384652682122!GO:0007052;mitotic spindle organization and biogenesis;0.000174612369564881!GO:0016023;cytoplasmic membrane-bound vesicle;0.000180243327494042!GO:0004527;exonuclease activity;0.000181441356380084!GO:0005048;signal sequence binding;0.000184912712426765!GO:0005791;rough endoplasmic reticulum;0.00018682848164912!GO:0003729;mRNA binding;0.000195617919406403!GO:0019899;enzyme binding;0.000211129112461722!GO:0046474;glycerophospholipid biosynthetic process;0.000217557227482383!GO:0006695;cholesterol biosynthetic process;0.000229260484639614!GO:0043681;protein import into mitochondrion;0.000239233720802068!GO:0006612;protein targeting to membrane;0.000245675667151688!GO:0032561;guanyl ribonucleotide binding;0.000248453847538782!GO:0019001;guanyl nucleotide binding;0.000248453847538782!GO:0006350;transcription;0.000249764099534367!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000319006697159238!GO:0008186;RNA-dependent ATPase activity;0.000354167013770418!GO:0051252;regulation of RNA metabolic process;0.000355914272393339!GO:0043069;negative regulation of programmed cell death;0.000358061114789973!GO:0005741;mitochondrial outer membrane;0.000368690946649501!GO:0009892;negative regulation of metabolic process;0.000371554527219203!GO:0016564;transcription repressor activity;0.00039270827215788!GO:0004576;oligosaccharyl transferase activity;0.000395137404395108!GO:0043066;negative regulation of apoptosis;0.000434348949807008!GO:0008250;oligosaccharyl transferase complex;0.00045553232541218!GO:0033116;ER-Golgi intermediate compartment membrane;0.000455679978016522!GO:0030880;RNA polymerase complex;0.000462634567070104!GO:0051789;response to protein stimulus;0.000471580076822958!GO:0006986;response to unfolded protein;0.000471580076822958!GO:0007017;microtubule-based process;0.000474989120605054!GO:0006414;translational elongation;0.000479359142846885!GO:0005885;Arp2/3 protein complex;0.000489691904253088!GO:0005684;U2-dependent spliceosome;0.000506364754236474!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.000506364754236474!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000509831275735779!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000521798520520296!GO:0005770;late endosome;0.000534608507105023!GO:0042981;regulation of apoptosis;0.000544432563786354!GO:0006839;mitochondrial transport;0.000544432563786354!GO:0051540;metal cluster binding;0.000559828223762893!GO:0051536;iron-sulfur cluster binding;0.000559828223762893!GO:0030133;transport vesicle;0.00057589669217753!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000582347674823787!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000594982703470905!GO:0003714;transcription corepressor activity;0.000617908002390009!GO:0031982;vesicle;0.000663476159879361!GO:0005905;coated pit;0.000666751817952148!GO:0043067;regulation of programmed cell death;0.000668425590509333!GO:0008610;lipid biosynthetic process;0.0007096914264846!GO:0046467;membrane lipid biosynthetic process;0.000718445918500924!GO:0006402;mRNA catabolic process;0.000724536625700251!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000726789811750888!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000734384804263411!GO:0000082;G1/S transition of mitotic cell cycle;0.000740083803450693!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000764122587177743!GO:0015631;tubulin binding;0.000774416916299236!GO:0030663;COPI coated vesicle membrane;0.000783243651440888!GO:0030126;COPI vesicle coat;0.000783243651440888!GO:0030036;actin cytoskeleton organization and biogenesis;0.000823067245635419!GO:0007006;mitochondrial membrane organization and biogenesis;0.000849643265609959!GO:0051920;peroxiredoxin activity;0.000958980396381699!GO:0004004;ATP-dependent RNA helicase activity;0.000965913821590922!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000967450923335178!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000967450923335178!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000967450923335178!GO:0016481;negative regulation of transcription;0.000969607055259938!GO:0031410;cytoplasmic vesicle;0.000989926671014937!GO:0043596;nuclear replication fork;0.00103805680987062!GO:0000922;spindle pole;0.00104055765440793!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00107953055439282!GO:0000428;DNA-directed RNA polymerase complex;0.00107953055439282!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00108739894349148!GO:0004518;nuclease activity;0.00108911389817878!GO:0031072;heat shock protein binding;0.00109293791476994!GO:0006401;RNA catabolic process;0.00109590387243895!GO:0032508;DNA duplex unwinding;0.00110404104943142!GO:0032392;DNA geometric change;0.00110404104943142!GO:0048500;signal recognition particle;0.0011162100499265!GO:0005876;spindle microtubule;0.00112471798909097!GO:0006891;intra-Golgi vesicle-mediated transport;0.00116956790804786!GO:0000049;tRNA binding;0.00121572445696211!GO:0006275;regulation of DNA replication;0.00123358433286869!GO:0000228;nuclear chromosome;0.00128128948514107!GO:0048471;perinuclear region of cytoplasm;0.00134121986344025!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00134811353766887!GO:0042802;identical protein binding;0.00135812748083338!GO:0018196;peptidyl-asparagine modification;0.0013995503657476!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0013995503657476!GO:0006352;transcription initiation;0.00142244825407808!GO:0008312;7S RNA binding;0.00162609250374442!GO:0030658;transport vesicle membrane;0.00167886390702605!GO:0000910;cytokinesis;0.00169117561750625!GO:0006268;DNA unwinding during replication;0.00169799033242649!GO:0010468;regulation of gene expression;0.0019380400268624!GO:0030137;COPI-coated vesicle;0.00199102332116801!GO:0008139;nuclear localization sequence binding;0.00202630321189542!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.00203275292484653!GO:0031124;mRNA 3'-end processing;0.00203616501408196!GO:0035258;steroid hormone receptor binding;0.00203895543874177!GO:0009112;nucleobase metabolic process;0.00205402076127701!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00206555078098049!GO:0051287;NAD binding;0.00214140115768103!GO:0043284;biopolymer biosynthetic process;0.00214651436685361!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00220523332132914!GO:0031570;DNA integrity checkpoint;0.00225265431188388!GO:0046489;phosphoinositide biosynthetic process;0.0024726579527262!GO:0006595;polyamine metabolic process;0.00258713710696206!GO:0030134;ER to Golgi transport vesicle;0.00263417256298714!GO:0008180;signalosome;0.00264083868638444!GO:0043488;regulation of mRNA stability;0.00267896589959852!GO:0043487;regulation of RNA stability;0.00267896589959852!GO:0050662;coenzyme binding;0.00273376806761094!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00289632906661715!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00289632906661715!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00298888742540515!GO:0045047;protein targeting to ER;0.00298888742540515!GO:0005637;nuclear inner membrane;0.00302415196126624!GO:0003677;DNA binding;0.00308359246452867!GO:0032984;macromolecular complex disassembly;0.00316398954502815!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00316614731663178!GO:0006520;amino acid metabolic process;0.00321169992876598!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00329063217343301!GO:0005096;GTPase activator activity;0.00329063217343301!GO:0006289;nucleotide-excision repair;0.00331780932913188!GO:0031901;early endosome membrane;0.00335213991429798!GO:0030127;COPII vesicle coat;0.00337901666124515!GO:0012507;ER to Golgi transport vesicle membrane;0.00337901666124515!GO:0051539;4 iron, 4 sulfur cluster binding;0.00343463713027164!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.00378896853081022!GO:0000725;recombinational repair;0.00383630321946398!GO:0000724;double-strand break repair via homologous recombination;0.00383630321946398!GO:0030132;clathrin coat of coated pit;0.00392953937435831!GO:0051087;chaperone binding;0.00393438711529316!GO:0043601;nuclear replisome;0.00395823258089021!GO:0030894;replisome;0.00395823258089021!GO:0046483;heterocycle metabolic process;0.00400371795890909!GO:0030029;actin filament-based process;0.00408599277122735!GO:0001726;ruffle;0.00413971738303177!GO:0004003;ATP-dependent DNA helicase activity;0.00439270822359022!GO:0006144;purine base metabolic process;0.00451282500405199!GO:0006220;pyrimidine nucleotide metabolic process;0.00451282500405199!GO:0004674;protein serine/threonine kinase activity;0.00488456817370431!GO:0006611;protein export from nucleus;0.0050127149896272!GO:0030660;Golgi-associated vesicle membrane;0.00502081417321563!GO:0003711;transcription elongation regulator activity;0.00513049692248327!GO:0006405;RNA export from nucleus;0.00520551816099948!GO:0043624;cellular protein complex disassembly;0.00522270147249533!GO:0030521;androgen receptor signaling pathway;0.00525654425313626!GO:0042770;DNA damage response, signal transduction;0.00533545531133878!GO:0043241;protein complex disassembly;0.00536619326506043!GO:0017166;vinculin binding;0.00542996856808501!GO:0006270;DNA replication initiation;0.00543146839166966!GO:0016272;prefoldin complex;0.00556756953404562!GO:0000070;mitotic sister chromatid segregation;0.00568746901667958!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00573038736403005!GO:0019752;carboxylic acid metabolic process;0.00573197534879118!GO:0000792;heterochromatin;0.00574234190766641!GO:0009116;nucleoside metabolic process;0.00576815022417759!GO:0006284;base-excision repair;0.00588618158936061!GO:0006082;organic acid metabolic process;0.00608210930489328!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.00609683938398159!GO:0030118;clathrin coat;0.00621863382639452!GO:0005758;mitochondrial intermembrane space;0.0063274694055798!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00634928111529642!GO:0000819;sister chromatid segregation;0.00650387515824259!GO:0003746;translation elongation factor activity;0.00672143883968561!GO:0008047;enzyme activator activity;0.006872188095663!GO:0016251;general RNA polymerase II transcription factor activity;0.006872188095663!GO:0032774;RNA biosynthetic process;0.00692351652018147!GO:0000339;RNA cap binding;0.00717988313347118!GO:0008652;amino acid biosynthetic process;0.00721213166482482!GO:0032200;telomere organization and biogenesis;0.00751120122560019!GO:0000723;telomere maintenance;0.00751120122560019!GO:0009303;rRNA transcription;0.00759769239789195!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00765410280067114!GO:0016408;C-acyltransferase activity;0.00771531592311429!GO:0008022;protein C-terminus binding;0.00778082396283375!GO:0031123;RNA 3'-end processing;0.00781874035977597!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00797729368712589!GO:0007346;regulation of progression through mitotic cell cycle;0.008014474975939!GO:0005832;chaperonin-containing T-complex;0.0080428215632715!GO:0030027;lamellipodium;0.0081361360553962!GO:0043022;ribosome binding;0.00824904214733489!GO:0000178;exosome (RNase complex);0.00843321712255639!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.00846302118436441!GO:0000077;DNA damage checkpoint;0.0087350550709705!GO:0031970;organelle envelope lumen;0.0087350550709705!GO:0006351;transcription, DNA-dependent;0.00877117361817494!GO:0019206;nucleoside kinase activity;0.00902022218074407!GO:0008361;regulation of cell size;0.00946922541333317!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0100250645747282!GO:0015002;heme-copper terminal oxidase activity;0.0100250645747282!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0100250645747282!GO:0004129;cytochrome-c oxidase activity;0.0100250645747282!GO:0030176;integral to endoplasmic reticulum membrane;0.0101298345455679!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0101425489636251!GO:0015992;proton transport;0.0103763144566208!GO:0016049;cell growth;0.0105394464359368!GO:0000084;S phase of mitotic cell cycle;0.0106381645138797!GO:0051053;negative regulation of DNA metabolic process;0.0107835375075062!GO:0006818;hydrogen transport;0.0110128487959731!GO:0006378;mRNA polyadenylation;0.0110128487959731!GO:0008408;3'-5' exonuclease activity;0.011053482778262!GO:0048037;cofactor binding;0.0110820086745438!GO:0000096;sulfur amino acid metabolic process;0.0113493294289289!GO:0007021;tubulin folding;0.011578364830271!GO:0009451;RNA modification;0.0117642854183781!GO:0008092;cytoskeletal protein binding;0.0120162904118131!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0121985641475358!GO:0006541;glutamine metabolic process;0.0123254243292496!GO:0016197;endosome transport;0.012499323924783!GO:0044454;nuclear chromosome part;0.0125636625542804!GO:0022411;cellular component disassembly;0.0128215012002669!GO:0030496;midbody;0.0132490419168794!GO:0006497;protein amino acid lipidation;0.0135927641164959!GO:0007050;cell cycle arrest;0.0137972931638607!GO:0009124;nucleoside monophosphate biosynthetic process;0.0141135449686574!GO:0009123;nucleoside monophosphate metabolic process;0.0141135449686574!GO:0005100;Rho GTPase activator activity;0.0141309596899761!GO:0005869;dynactin complex;0.0141549044518907!GO:0048487;beta-tubulin binding;0.0141549044518907!GO:0006740;NADPH regeneration;0.0145580636039281!GO:0006098;pentose-phosphate shunt;0.0145580636039281!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0145747138910631!GO:0015399;primary active transmembrane transporter activity;0.0145747138910631!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0148773708684208!GO:0030145;manganese ion binding;0.0151582011570084!GO:0065007;biological regulation;0.0151582011570084!GO:0043189;H4/H2A histone acetyltransferase complex;0.0151906293160664!GO:0004532;exoribonuclease activity;0.0153392067648243!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0153392067648243!GO:0000209;protein polyubiquitination;0.0156571063001334!GO:0031625;ubiquitin protein ligase binding;0.0158732952624824!GO:0042393;histone binding;0.0159855764461988!GO:0005663;DNA replication factor C complex;0.0162695237384322!GO:0051320;S phase;0.0163417134454658!GO:0006650;glycerophospholipid metabolic process;0.0166057549772705!GO:0035267;NuA4 histone acetyltransferase complex;0.0167713857295667!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0173243299082869!GO:0000287;magnesium ion binding;0.0175839829625156!GO:0006778;porphyrin metabolic process;0.0177585786089139!GO:0033013;tetrapyrrole metabolic process;0.0177585786089139!GO:0065009;regulation of a molecular function;0.0177635486633438!GO:0006338;chromatin remodeling;0.0178436974719648!GO:0016407;acetyltransferase activity;0.0180761359463473!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0181162563803699!GO:0030119;AP-type membrane coat adaptor complex;0.0181162563803699!GO:0030041;actin filament polymerization;0.0184968908058124!GO:0005862;muscle thin filament tropomyosin;0.0185650953028884!GO:0046112;nucleobase biosynthetic process;0.0189988463332405!GO:0022890;inorganic cation transmembrane transporter activity;0.0194833657543639!GO:0000781;chromosome, telomeric region;0.0196603355653096!GO:0000152;nuclear ubiquitin ligase complex;0.0196603355653096!GO:0000726;non-recombinational repair;0.0196603355653096!GO:0016584;nucleosome positioning;0.0196882080758336!GO:0030659;cytoplasmic vesicle membrane;0.0196882080758336!GO:0006506;GPI anchor biosynthetic process;0.0197187517539864!GO:0008299;isoprenoid biosynthetic process;0.0199873049123889!GO:0006950;response to stress;0.0200445024439092!GO:0016044;membrane organization and biogenesis;0.0200561475392821!GO:0050681;androgen receptor binding;0.0200561475392821!GO:0006779;porphyrin biosynthetic process;0.0200739921515838!GO:0033014;tetrapyrrole biosynthetic process;0.0200739921515838!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0201969524321474!GO:0004523;ribonuclease H activity;0.0205645782014113!GO:0030125;clathrin vesicle coat;0.020672569884738!GO:0030665;clathrin coated vesicle membrane;0.020672569884738!GO:0016125;sterol metabolic process;0.0209172928557247!GO:0044262;cellular carbohydrate metabolic process;0.020945006170765!GO:0004177;aminopeptidase activity;0.021133961115729!GO:0006007;glucose catabolic process;0.0218719697420282!GO:0005669;transcription factor TFIID complex;0.022236441957906!GO:0006376;mRNA splice site selection;0.0224901446548913!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0224901446548913!GO:0008234;cysteine-type peptidase activity;0.0228757567338229!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0231997773957238!GO:0045449;regulation of transcription;0.0232055054358423!GO:0001558;regulation of cell growth;0.023295970750003!GO:0045892;negative regulation of transcription, DNA-dependent;0.0240233995624557!GO:0046128;purine ribonucleoside metabolic process;0.024248350104002!GO:0042278;purine nucleoside metabolic process;0.024248350104002!GO:0048522;positive regulation of cellular process;0.0245473813613489!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0249153038303736!GO:0006509;membrane protein ectodomain proteolysis;0.0250716947653908!GO:0033619;membrane protein proteolysis;0.0250716947653908!GO:0019783;small conjugating protein-specific protease activity;0.0252839401579615!GO:0009262;deoxyribonucleotide metabolic process;0.0252949313208182!GO:0030508;thiol-disulfide exchange intermediate activity;0.0253875347234066!GO:0031371;ubiquitin conjugating enzyme complex;0.0258326980422791!GO:0006505;GPI anchor metabolic process;0.0262819030839746!GO:0006607;NLS-bearing substrate import into nucleus;0.0264079691129635!GO:0030032;lamellipodium biogenesis;0.0265300454046075!GO:0003756;protein disulfide isomerase activity;0.0265587419869126!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0265587419869126!GO:0008243;plasminogen activator activity;0.0267661120375848!GO:0016581;NuRD complex;0.0267661120375848!GO:0000793;condensed chromosome;0.026924353608084!GO:0004448;isocitrate dehydrogenase activity;0.0270735057669593!GO:0008632;apoptotic program;0.0274800831961706!GO:0051537;2 iron, 2 sulfur cluster binding;0.0275854405800073!GO:0003887;DNA-directed DNA polymerase activity;0.0278891468427185!GO:0031529;ruffle organization and biogenesis;0.0287686190503069!GO:0009161;ribonucleoside monophosphate metabolic process;0.0287686190503069!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0287686190503069!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0294983690283324!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0297592554134691!GO:0031577;spindle checkpoint;0.0298146281078753!GO:0000118;histone deacetylase complex;0.0303867267061784!GO:0000123;histone acetyltransferase complex;0.0303867267061784!GO:0009225;nucleotide-sugar metabolic process;0.0304094789895578!GO:0008276;protein methyltransferase activity;0.0304940597450194!GO:0004843;ubiquitin-specific protease activity;0.0305472248871413!GO:0030384;phosphoinositide metabolic process;0.0305487907729835!GO:0032259;methylation;0.0307690919703541!GO:0008017;microtubule binding;0.0310301121104812!GO:0030131;clathrin adaptor complex;0.0311431623141543!GO:0030911;TPR domain binding;0.0322702250743124!GO:0006221;pyrimidine nucleotide biosynthetic process;0.0323390947414862!GO:0007004;telomere maintenance via telomerase;0.0325949913348535!GO:0005875;microtubule associated complex;0.0329060946559808!GO:0008156;negative regulation of DNA replication;0.0334743477412251!GO:0048146;positive regulation of fibroblast proliferation;0.03377669513647!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0340430663522769!GO:0010257;NADH dehydrogenase complex assembly;0.0340430663522769!GO:0033108;mitochondrial respiratory chain complex assembly;0.0340430663522769!GO:0005881;cytoplasmic microtubule;0.0340815316279181!GO:0006400;tRNA modification;0.0341165388360354!GO:0043130;ubiquitin binding;0.0342700269798471!GO:0032182;small conjugating protein binding;0.0342700269798471!GO:0042158;lipoprotein biosynthetic process;0.0344803928896494!GO:0006266;DNA ligation;0.0346522007376483!GO:0005784;translocon complex;0.0351239146587307!GO:0030518;steroid hormone receptor signaling pathway;0.0354177192608287!GO:0006360;transcription from RNA polymerase I promoter;0.0356095730989918!GO:0012506;vesicle membrane;0.0364846901545286!GO:0007264;small GTPase mediated signal transduction;0.0365040102446592!GO:0045941;positive regulation of transcription;0.0370314272586264!GO:0033673;negative regulation of kinase activity;0.0370616829819234!GO:0006469;negative regulation of protein kinase activity;0.0370616829819234!GO:0005773;vacuole;0.0377508330085512!GO:0044450;microtubule organizing center part;0.0377698856108448!GO:0008287;protein serine/threonine phosphatase complex;0.0385432726034356!GO:0006596;polyamine biosynthetic process;0.0385432726034356!GO:0005680;anaphase-promoting complex;0.0392454975620651!GO:0043414;biopolymer methylation;0.0392770504894369!GO:0048144;fibroblast proliferation;0.0393895628299701!GO:0048145;regulation of fibroblast proliferation;0.0393895628299701!GO:0044433;cytoplasmic vesicle part;0.0396806653424125!GO:0008143;poly(A) binding;0.0397565387383671!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.039991903773293!GO:0045039;protein import into mitochondrial inner membrane;0.039991903773293!GO:0042026;protein refolding;0.0400675317408941!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0406078553369374!GO:0051348;negative regulation of transferase activity;0.0409016110561964!GO:0016301;kinase activity;0.0412701461462446!GO:0009067;aspartate family amino acid biosynthetic process;0.0414494798218807!GO:0008097;5S rRNA binding;0.041513583988994!GO:0006739;NADP metabolic process;0.0418093646089989!GO:0004221;ubiquitin thiolesterase activity;0.0422995112443317!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0423497536181664!GO:0045893;positive regulation of transcription, DNA-dependent;0.0430316715978842!GO:0050178;phenylpyruvate tautomerase activity;0.0430453762367523!GO:0016417;S-acyltransferase activity;0.0437312065752486!GO:0009119;ribonucleoside metabolic process;0.0445156777681066!GO:0005652;nuclear lamina;0.0445253801059277!GO:0006118;electron transport;0.0445253801059277!GO:0009066;aspartate family amino acid metabolic process;0.0445253801059277!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0445667344525301!GO:0007034;vacuolar transport;0.0448571690314183!GO:0042168;heme metabolic process;0.0448656559699216!GO:0030433;ER-associated protein catabolic process;0.0451733376952622!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0451733376952622!GO:0004722;protein serine/threonine phosphatase activity;0.0453645624728412!GO:0004239;methionyl aminopeptidase activity;0.0456372241445367!GO:0017134;fibroblast growth factor binding;0.0456848921400941!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0457993069211662!GO:0016790;thiolester hydrolase activity;0.0461575580676626!GO:0005732;small nucleolar ribonucleoprotein complex;0.046165142757915!GO:0006301;postreplication repair;0.0478298766627681!GO:0003985;acetyl-CoA C-acetyltransferase activity;0.048108213223169!GO:0008629;induction of apoptosis by intracellular signals;0.0482256028492579!GO:0001832;blastocyst growth;0.0482256028492579!GO:0030866;cortical actin cytoskeleton organization and biogenesis;0.0491369761777516!GO:0006892;post-Golgi vesicle-mediated transport;0.0491736785980967 | |||
|sample_id=11458 | |||
|sample_note= | |||
|sample_sex=unknown | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=skin | |||
|top_motifs=TFDP1:1.85119842042;NKX3-1:1.68580618085;PAX8:1.49827492548;POU1F1:1.40405748577;E2F1..5:1.39729099531;GFI1:1.33078992701;NFY{A,B,C}:1.13793638375;TOPORS:1.10305413785;NKX2-2,8:1.09100315953;PDX1:1.01365362616;ALX4:0.973164212003;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.955474767123;EN1,2:0.914915320169;NR3C1:0.890573970933;MYB:0.88632299984;HOXA9_MEIS1:0.88234759705;ZNF143:0.847472444356;ZNF238:0.791805027672;NRF1:0.736511081121;GZF1:0.658287751904;NANOG{mouse}:0.654566602939;PAX4:0.611493379521;SOX17:0.606945677553;GFI1B:0.6047734169;YY1:0.598908850088;ELK1,4_GABP{A,B1}:0.595829977871;ZIC1..3:0.595047573482;POU2F1..3:0.563138243953;HES1:0.559660683767;POU3F1..4:0.515088041857;PRRX1,2:0.499654536241;PBX1:0.492083627222;PITX1..3:0.480091653842;HOX{A5,B5}:0.475774665316;UFEwm:0.446830862506;FOXP1:0.444978959914;NKX2-3_NKX2-5:0.426156985841;NFIX:0.409727047765;RXR{A,B,G}:0.399111403984;HBP1_HMGB_SSRP1_UBTF:0.387071817708;CDC5L:0.382682279228;PAX3,7:0.381571233059;BREu{core}:0.372517542072;TEAD1:0.360595204;NKX6-1,2:0.345392429889;FOXD3:0.343008125968;KLF4:0.339809680697;GCM1,2:0.339568798089;BACH2:0.339348458879;MZF1:0.329916140165;CRX:0.317033467501;T:0.311883983963;SPZ1:0.292338621315;LEF1_TCF7_TCF7L1,2:0.287058926326;AHR_ARNT_ARNT2:0.286509916213;AIRE:0.260188901806;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.256023403464;ONECUT1,2:0.253993198169;XCPE1{core}:0.251796896229;TEF:0.25177893935;TFAP2{A,C}:0.244408640165;FOS_FOS{B,L1}_JUN{B,D}:0.232925365775;PAX5:0.219897039374;EVI1:0.208430731177;XBP1:0.196666906085;MYBL2:0.17695718018;PRDM1:0.168329026034;AR:0.14908266644;NR1H4:0.147234146863;ATF6:0.146966252148;PAX1,9:0.140706438501;CREB1:0.125646029652;NKX2-1,4:0.119893148935;TBX4,5:0.116217254544;TAL1_TCF{3,4,12}:0.101603098793;ZBTB16:0.0776652710525;SRF:0.069386525003;HOX{A4,D4}:0.0546922521836;TFAP4:0.0523396543469;HSF1,2:0.0441713263257;STAT5{A,B}:0.0436822198071;GATA4:0.0420362387204;NFE2L2:0.0269526739497;TP53:0.0156254779891;LHX3,4:0.0125519087514;HIC1:0.0116829047386;FOSL2:-0.00874351867525;ELF1,2,4:-0.016993955662;SOX5:-0.0229688356421;SOX{8,9,10}:-0.0248189920543;FOXM1:-0.0305919151226;HNF1A:-0.0481404312435;NFATC1..3:-0.0531014957243;NANOG:-0.0539696065486;GTF2I:-0.0568614848234;TLX1..3_NFIC{dimer}:-0.0599450499672;ALX1:-0.0615436052848;NKX3-2:-0.0797810193367;TGIF1:-0.109887874106;TFAP2B:-0.112077769842;HLF:-0.112641224927;NR5A1,2:-0.121122595053;HNF4A_NR2F1,2:-0.129289715086;IKZF1:-0.138253119738;CEBPA,B_DDIT3:-0.145748714321;ESR1:-0.15458561831;HIF1A:-0.160095971034;VSX1,2:-0.175478297005;bHLH_family:-0.180096707926;HOX{A6,A7,B6,B7}:-0.206654136204;FOXL1:-0.206915287056;ZFP161:-0.212675610398;MTF1:-0.214151807997;FOX{I1,J2}:-0.219681628569;RFX1:-0.22188007399;ZNF384:-0.230049903231;NFE2:-0.230166330071;RUNX1..3:-0.236888499484;ZBTB6:-0.250007328164;STAT1,3:-0.257779140816;DMAP1_NCOR{1,2}_SMARC:-0.259533401282;GATA6:-0.270167098612;POU6F1:-0.285009684539;IKZF2:-0.288101877566;NFE2L1:-0.289545386138;GTF2A1,2:-0.291738321703;SOX2:-0.294018313368;ESRRA:-0.298114176995;OCT4_SOX2{dimer}:-0.303084208188;MEF2{A,B,C,D}:-0.311890585694;DBP:-0.313613972495;TBP:-0.314476976457;EGR1..3:-0.325311241232;MTE{core}:-0.327276761853;REST:-0.333822832371;NFKB1_REL_RELA:-0.337904146821;SP1:-0.338568307572;ATF4:-0.346252884996;PAX2:-0.348637967051;SPI1:-0.34938699292;PATZ1:-0.35063820187;CDX1,2,4:-0.353806703378;HAND1,2:-0.35593490577;ADNP_IRX_SIX_ZHX:-0.356955218944;ARID5B:-0.358024978114;ATF5_CREB3:-0.36873012717;RFX2..5_RFXANK_RFXAP:-0.369699900777;MED-1{core}:-0.374779463545;NHLH1,2:-0.376878653536;FOXQ1:-0.387998015737;POU5F1:-0.402537983297;FOXA2:-0.421959909552;HMGA1,2:-0.424589995017;STAT2,4,6:-0.444551610865;CUX2:-0.475788976462;NR6A1:-0.508135039962;SPIB:-0.516937989325;MAZ:-0.527578677232;BPTF:-0.554312612391;JUN:-0.56041203314;TFCP2:-0.570003628639;PPARG:-0.581227159168;RXRA_VDR{dimer}:-0.589138514084;ETS1,2:-0.601925180214;ZNF148:-0.612225472895;ZNF423:-0.625030017863;EP300:-0.636669690558;RBPJ:-0.649002977578;RREB1:-0.664590563314;MYFfamily:-0.664816463977;ATF2:-0.668352796524;FOXO1,3,4:-0.676460518409;GLI1..3:-0.677371292648;FOXN1:-0.707717376253;SMAD1..7,9:-0.708458006884;FOXP3:-0.711543051443;PAX6:-0.713717544094;EBF1:-0.751562178714;MAFB:-0.751983250077;NFIL3:-0.761042611558;SNAI1..3:-0.770849438154;FOX{F1,F2,J1}:-0.772503738979;IRF1,2:-0.817506239682;HMX1:-0.860408985643;IRF7:-0.872004733985;SREBF1,2:-0.984949202263;LMO2:-0.999940612369;MYOD1:-1.02069896287;ZEB1:-1.02391647086;TLX2:-1.02852399625;RORA:-1.04802800544;FOX{D1,D2}:-1.17415576506 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11458-119A9;search_select_hide=table117:FF:11458-119A9 | |||
}} | }} |
Latest revision as of 18:02, 4 June 2020
Name: | Fibroblast - Dermal, donor6 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs12059 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12059
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12059
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.706 |
10 | 10 | 0.204 |
100 | 100 | 0.601 |
101 | 101 | 0.381 |
102 | 102 | 0.346 |
103 | 103 | 0.0767 |
104 | 104 | 0.987 |
105 | 105 | 0.708 |
106 | 106 | 5.97005e-4 |
107 | 107 | 0.171 |
108 | 108 | 0.216 |
109 | 109 | 0.908 |
11 | 11 | 0.784 |
110 | 110 | 0.484 |
111 | 111 | 0.521 |
112 | 112 | 0.0534 |
113 | 113 | 0.0279 |
114 | 114 | 0.25 |
115 | 115 | 0.776 |
116 | 116 | 0.432 |
117 | 117 | 0.674 |
118 | 118 | 0.896 |
119 | 119 | 0.126 |
12 | 12 | 0.483 |
120 | 120 | 0.241 |
121 | 121 | 0.994 |
122 | 122 | 0.11 |
123 | 123 | 0.784 |
124 | 124 | 0.392 |
125 | 125 | 0.569 |
126 | 126 | 0.851 |
127 | 127 | 0.619 |
128 | 128 | 0.0171 |
129 | 129 | 0.144 |
13 | 13 | 0.684 |
130 | 130 | 0.0186 |
131 | 131 | 0.766 |
132 | 132 | 0.934 |
133 | 133 | 0.74 |
134 | 134 | 0.582 |
135 | 135 | 0.0106 |
136 | 136 | 0.5 |
137 | 137 | 0.179 |
138 | 138 | 0.251 |
139 | 139 | 9.22491e-6 |
14 | 14 | 0.179 |
140 | 140 | 0.839 |
141 | 141 | 0.701 |
142 | 142 | 0.536 |
143 | 143 | 0.335 |
144 | 144 | 0.683 |
145 | 145 | 0.397 |
146 | 146 | 0.717 |
147 | 147 | 0.539 |
148 | 148 | 0.338 |
149 | 149 | 0.208 |
15 | 15 | 0.283 |
150 | 150 | 0.982 |
151 | 151 | 0.418 |
152 | 152 | 0.0618 |
153 | 153 | 0.261 |
154 | 154 | 0.427 |
155 | 155 | 0.0826 |
156 | 156 | 0.684 |
157 | 157 | 0.183 |
158 | 158 | 0.0292 |
159 | 159 | 0.0295 |
16 | 16 | 0.626 |
160 | 160 | 0.523 |
161 | 161 | 0.458 |
162 | 162 | 0.815 |
163 | 163 | 0.904 |
164 | 164 | 0.76 |
165 | 165 | 0.255 |
166 | 166 | 0.87 |
167 | 167 | 0.576 |
168 | 168 | 0.445 |
169 | 169 | 0.104 |
17 | 17 | 0.399 |
18 | 18 | 0.817 |
19 | 19 | 0.515 |
2 | 2 | 0.559 |
20 | 20 | 0.21 |
21 | 21 | 0.0442 |
22 | 22 | 0.241 |
23 | 23 | 0.0351 |
24 | 24 | 0.439 |
25 | 25 | 0.988 |
26 | 26 | 0.327 |
27 | 27 | 0.471 |
28 | 28 | 0.554 |
29 | 29 | 0.983 |
3 | 3 | 0.691 |
30 | 30 | 0.383 |
31 | 31 | 0.489 |
32 | 32 | 0.605 |
33 | 33 | 0.426 |
34 | 34 | 0.263 |
35 | 35 | 0.453 |
36 | 36 | 0.874 |
37 | 37 | 0.448 |
38 | 38 | 0.41 |
39 | 39 | 0.933 |
4 | 4 | 0.138 |
40 | 40 | 0.539 |
41 | 41 | 0.135 |
42 | 42 | 0.979 |
43 | 43 | 0.222 |
44 | 44 | 0.766 |
45 | 45 | 0.0648 |
46 | 46 | 0.498 |
47 | 47 | 0.833 |
48 | 48 | 0.573 |
49 | 49 | 0.3 |
5 | 5 | 0.162 |
50 | 50 | 0.614 |
51 | 51 | 0.661 |
52 | 52 | 0.0932 |
53 | 53 | 0.547 |
54 | 54 | 0.499 |
55 | 55 | 0.708 |
56 | 56 | 0.753 |
57 | 57 | 0.54 |
58 | 58 | 0.126 |
59 | 59 | 0.226 |
6 | 6 | 0.748 |
60 | 60 | 0.0177 |
61 | 61 | 0.963 |
62 | 62 | 0.177 |
63 | 63 | 0.862 |
64 | 64 | 0.932 |
65 | 65 | 0.158 |
66 | 66 | 0.057 |
67 | 67 | 0.788 |
68 | 68 | 0.994 |
69 | 69 | 0.743 |
7 | 7 | 0.495 |
70 | 70 | 0.00218 |
71 | 71 | 0.96 |
72 | 72 | 0.179 |
73 | 73 | 0.468 |
74 | 74 | 0.143 |
75 | 75 | 0.597 |
76 | 76 | 0.703 |
77 | 77 | 0.544 |
78 | 78 | 0.834 |
79 | 79 | 0.597 |
8 | 8 | 0.965 |
80 | 80 | 0.0292 |
81 | 81 | 0.357 |
82 | 82 | 0.0126 |
83 | 83 | 0.385 |
84 | 84 | 0.778 |
85 | 85 | 0.00614 |
86 | 86 | 0.426 |
87 | 87 | 0.176 |
88 | 88 | 0.379 |
89 | 89 | 0.1 |
9 | 9 | 0.531 |
90 | 90 | 0.62 |
91 | 91 | 0.545 |
92 | 92 | 0.176 |
93 | 93 | 0.826 |
94 | 94 | 0.863 |
95 | 95 | 0.249 |
96 | 96 | 0.369 |
97 | 97 | 0.752 |
98 | 98 | 0.448 |
99 | 99 | 0.0789 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12059
FANTOM5 (FF) ontology
Direct parent terms
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0002320 (connective tissue cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
0000057 (fibroblast)
0002620 (skin fibroblast)
0002551 (fibroblast of dermis)
UBERON: Anatomy
0000468 (multi-cellular organism)
0002097 (skin of body)
0002199 (integument)
0002384 (connective tissue)
0000479 (tissue)
0000064 (organ part)
0010314 (structure with developmental contribution from neural crest)
0000062 (organ)
0004120 (mesoderm-derived structure)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0004923 (organ component layer)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0003102 (surface structure)
0010317 (germ layer / neural crest derived structure)
0002067 (dermis)
0002416 (integumental system)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000057 (fibroblast sample)
0000250 (human fibroblast of skin sample)
0000001 (sample)
0000062 (human dermal fibroblast sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)