FF:11555-120C7: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005869 | ||
| | |accession_numbers=CAGE;DRX008289;DRR009161;DRZ000586;DRZ001971;DRZ011936;DRZ013321 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002097,UBERON:0002199,UBERON:0002384,UBERON:0000479,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0003102,UBERON:0002416 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0002320,CL:0002371,CL:0000255,CL:0000057,CL:0002620 | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000057,FF:0000250,FF:0000001,FF:0000251 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr1:197886461..197886558,+!p1@LHX9!2.39!246.23!LHX9;;chr2:239756671..239756732,+!p1@TWIST2!1.87!227.73!TWIST2;;chr4:174451370..174451387,-!p1@HAND2!1.72!51.73!HAND2;;chr7:19157248..19157268,-!p1@TWIST1!1.71!134.30!TWIST1;;chr12:54410664..54410684,+!p1@HOXC4,p1@HOXC5,p1@HOXC6!1.71!50.35!HOXC5;;chr15:57511609..57511651,+!p2@TCF12!1.62!66.55!TCF12;;chr2:239756739..239756755,+!p2@TWIST2!1.61!66.92!TWIST2;;chr9:132427883..132427951,+!p2@PRRX2!1.57!35.81!PRRX2;;chr10:119303078..119303169,+!p2@EMX2!1.54!33.97!EMX2;;chr10:119302232..119302265,+!p1@EMX2!1.49!29.64!EMX2;;chr11:46299199..46299233,+!p1@CREB3L1!1.45!134.39!CREB3L1;;chr5:72744594..72744609,-!p1@FOXD1!1.42!113.31!FOXD1;;chr9:132427972..132428056,+!p1@PRRX2!1.42!32.86!PRRX2;;chr1:170632285..170632309,+!p1@PRRX1!1.39!26.69!PRRX1;;chr10:28034739..28034756,-!p1@MKX!1.39!23.75!MKX;;chr4:174450089..174450153,-!p2@HAND2!1.38!23.10!HAND2;;chr18:53068911..53068935,-!p4@TCF4!1.31!22.00!TCF4;;chr8:93074803..93074845,-!p1@RUNX1T1!1.30!18.78!RUNX1T1;;chr7:27224842..27224872,-!p1@HOXA11!1.27!17.67!HOXA11;;chr5:2751762..2751784,-!p1@IRX2!1.26!17.40!IRX2;;chr7:27224795..27224840,-!p2@HOXA11!1.26!17.21!HOXA11;;chr2:19558373..19558392,-!p1@OSR1!1.25!45.29!OSR1;;chr19:13134772..13134822,+!p2@NFIX!1.25!24.39!NFIX;;chr12:54402745..54402788,+!p1@HOXC8!1.22!15.46!HOXC8;;chr2:176969097..176969109,+!p3@HOXD11!1.17!13.62!HOXD11;;chr12:54410639..54410659,+!p2@HOXC4,p2@HOXC5,p2@HOXC6!1.16!13.35!HOXC5;;chr1:170633348..170633399,+!p2@PRRX1!1.15!17.86!PRRX1;;chr10:63809013..63809041,+!p3@ARID5B!1.14!70.23!ARID5B;;chr7:27205136..27205164,-!p1@HOXA9!1.14!12.70!HOXA9;;chr7:27213893..27213954,-!p1@HOXA10!1.09!11.23!HOXA10;;chr3:157823517..157823562,-!p1@SHOX2!1.06!11.23!SHOX2;;chrY:2803415..2803468,+!p1@ZFY!1.06!10.49!ZFY;;chr1:197886665..197886732,+!p3@LHX9!1.06!10.49!LHX9;;chr5:72744445..72744466,-!p2@FOXD1!1.05!17.21!FOXD1;;chr4:174451350..174451363,-!p3@HAND2!1.04!10.03!HAND2;;chr8:93074848..93074871,-!p3@RUNX1T1!1.04!9.94!RUNX1T1;;chr3:141121847..141121868,+!p5@ZBTB38!1.03!15.00!ZBTB38;;chr20:55204351..55204377,+!p1@TFAP2C!1.03!12.43!TFAP2C;;chrY:21906594..21906622,-!p1@KDM5D!1.03!9.67!KDM5D;;chr1:197886421..197886432,+!p2@LHX9!1.02!9.57!LHX9;;chr2:176994408..176994492,+!p1@HOXD8!1.02!9.48!HOXD8;;chr7:27192185..27192209,-!p1@HOXA3!1.02!9.48!HOXA3;;chr2:176969124..176969155,+!p5@HOXD11!1.01!9.20!HOXD11;;chr8:99956662..99956684,+!p1@OSR2!0.98!13.26!OSR2;;chr16:86544113..86544145,+!p1@FOXF1!0.98!10.68!FOXF1;;chr7:27205106..27205134,-!p2@HOXA9!0.98!8.65!HOXA9;;chr5:321810..321877,+!p1@AHRR!0.97!27.43!AHRR;;chr2:176969228..176969260,+!p1@HOXD11!0.97!8.28!HOXD11;;chr10:63809106..63809127,+!p1@ARID5B!0.96!112.67!ARID5B;;chr6:134210243..134210257,+!p1@TCF21!0.96!8.19!TCF21;;chr2:176969179..176969226,+!p2@HOXD11!0.96!8.10!HOXD11;;chr3:147111231..147111281,+!p3@ZIC1!0.96!8.10!ZIC1;;chr7:42276787..42276815,-!p1@GLI3!0.95!21.72!GLI3;;chr1:54204818..54204870,-!p@chr1:54204818..54204870,-!0.95!8.47!GLIS1;;chr10:119302645..119302712,+!p3@EMX2!0.95!8.01!EMX2;;chr16:31076332..31076388,-!p3@ZNF668!0.94!7.64!ZNF668;;chr3:147111198..147111225,+!p4@ZIC1!0.93!7.46!ZIC1;;chr7:44143925..44143970,+!p1@AEBP1!0.92!170.20!AEBP1;;chr11:46299539..46299620,+!p2@CREB3L1!0.92!12.79!CREB3L1;;chr10:63809077..63809089,+!p5@ARID5B!0.88!14.82!ARID5B;;chr16:54964740..54964789,+!p1@IRX5!0.88!9.67!IRX5;;chr10:119302508..119302559,+!p5@EMX2!0.88!6.63!EMX2;;chr10:31610110..31610159,+!p2@ZEB1!0.88!6.54!ZEB1;;chr15:37390850..37390909,-!p3@MEIS2!0.87!13.07!MEIS2;;chr19:13135386..13135435,+!p4@NFIX!0.87!6.44!NFIX;;chr10:119302268..119302282,+!p4@EMX2!0.87!6.44!EMX2;;chr8:49833978..49833996,-!p1@SNAI2!0.86!135.22!SNAI2;;chr6:85474299..85474324,-!p1@TBX18!0.86!11.60!TBX18;;chr15:37392724..37392757,-!p1@MEIS2!0.85!29.64!MEIS2;;chr6:19837592..19837621,+!p1@ID4!0.84!38.29!ID4;;chr22:19748231..19748317,+!p1@TBX1!0.84!5.89!TBX1;;chr10:28032421..28032494,-!p2@MKX!0.84!5.89!MKX;;chr8:49833948..49833973,-!p2@SNAI2!0.83!39.31!SNAI2;;chr15:42749722..42749739,-!p2@ZFP106!0.83!10.86!ZFP106;;chr1:170632959..170632987,+!p4@PRRX1!0.83!6.44!PRRX1;;chr14:24837368..24837401,+!p1@NFATC4!0.82!13.90!NFATC4;;chr14:75894714..75894733,+!p1@JDP2!0.81!167.44!JDP2;;chr12:53614115..53614154,-!p1@RARG!0.81!31.20!RARG;;chr7:44143978..44143989,+!p2@AEBP1!0.81!10.49!AEBP1;;chr15:83953397..83953425,-!p1@BNC1!0.81!6.35!BNC1;;chr5:3595934..3595957,+!p2@IRX1!0.81!5.43!IRX1;;chr3:138665937..138665968,-!p1@FOXL2!0.81!5.43!FOXL2;;chr15:57511589..57511608,+!p4@TCF12!0.80!5.34!TCF12;;chr3:21792585..21792625,-!p2@ZNF385D!0.79!5.89!ZNF385D;;chr5:158526917..158526932,-!p1@EBF1!0.78!13.44!EBF1;;chr6:10415276..10415341,-!p2@TFAP2A!0.78!6.26!TFAP2A;;chr19:13135582..13135600,+!p3@NFIX!0.78!4.97!NFIX;;chr15:37392616..37392638,-!p2@MEIS2!0.77!16.66!MEIS2;;chr5:2751785..2751808,-!p2@IRX2!0.77!4.88!IRX2;;chr19:47523058..47523114,+!p1@NPAS1!0.77!4.88!NPAS1;;chr1:158969752..158969780,+!p6@IFI16!0.76!8.65!IFI16;;chr12:54402790..54402805,+!p2@HOXC8!0.76!4.79!HOXC8;;chr13:45151259..45151326,-!p2@TSC22D1!0.75!30.47!TSC22D1;;chr2:102091566..102091581,-!p1@RFX8!0.75!4.60!RFX8;;chr4:4861385..4861398,+!p1@MSX1!0.74!14.45!MSX1;;chr6:10412600..10412637,-!p1@TFAP2A!0.74!7.92!TFAP2A;;chr12:80085061..80085119,-!p6@PAWR!0.74!7.46!PAWR;;chr7:27196267..27196311,-!p1@HOXA7!0.74!4.51!HOXA7;;chr9:2015335..2015370,+!p1@SMARCA2!0.73!59.28!SMARCA2;;chr14:62162285..62162296,+!p3@HIF1A!0.73!25.31!HIF1A;;chr11:65687362..65687436,+!p3@DRAP1!0.73!22.00!DRAP1;;chr9:2015306..2015323,+!p3@SMARCA2!0.72!12.06!SMARCA2;;chr1:170633262..170633285,+!p3@PRRX1!0.72!4.97!PRRX1;;chr12:54393880..54393962,+!p1@HOXC9!0.72!4.23!HOXC9;;chr14:62162258..62162269,+!p2@HIF1A!0.71!44.74!HIF1A;;chr3:24536253..24536328,-!p1@THRB!0.71!8.28!THRB;;chr6:85473156..85473210,-!p2@TBX18!0.71!5.25!TBX18;;chr14:61116183..61116208,-!p1@SIX1!0.70!17.03!SIX1;;chr10:119302182..119302196,+!p6@EMX2!0.70!4.05!EMX2;;chr1:119530493..119530572,-!p1@TBX15!0.70!4.05!TBX15;;chr8:93115274..93115323,-!p4@RUNX1T1!0.70!3.96!RUNX1T1;;chr10:119301928..119301955,+!p7@EMX2!0.70!3.96!EMX2;;chr2:119604456..119604501,-!p2@EN1!0.70!3.96!EN1;;chr3:147110055..147110129,-!p1@ZIC4!0.70!3.96!ZIC4;;chr19:13106214..13106382,+!p1@NFIX!0.69!104.02!NFIX;;chr7:19157043..19157088,-!p2@TWIST1!0.69!10.68!TWIST1;;chr1:23696448..23696453,-!p5@ZNF436!0.69!4.97!ZNF436;;chr5:142780189..142780223,-!p6@NR3C1!0.69!3.87!NR3C1;;chr10:31607702..31607755,+!p3@ZEB1!0.68!4.51!ZEB1;;chr1:170632250..170632277,+!p7@PRRX1!0.68!3.77!PRRX1;;chr12:115121962..115121987,-!p1@TBX3!0.67!35.35!TBX3;;chr6:1389789..1389821,+!p1@FOXF2!0.67!5.25!FOXF2;;chr5:72744562..72744573,-!p3@FOXD1!0.67!4.79!FOXD1;;chr6:100912785..100912822,-!p1@SIM1!0.67!3.68!SIM1;;chr3:141121820..141121838,+!p9@ZBTB38!0.67!3.68!ZBTB38;;chr10:28035133..28035148,-!p3@MKX!0.67!3.68!MKX;;chr12:54394309..54394336,+!p2@HOXC9!0.67!3.68!HOXC9;;chr18:22932080..22932170,-!p1@ZNF521!0.66!17.31!ZNF521;;chr21:36421535..36421610,-!p2@RUNX1!0.66!14.54!RUNX1;;chr15:37390482..37390572,-!p7@MEIS2!0.66!5.15!MEIS2;;chr1:170633058..170633084,+!p5@PRRX1!0.66!3.59!PRRX1;;chr12:114843940..114843955,-!p2@TBX5!0.66!3.59!TBX5;;chr10:114709999..114710031,+!p1@TCF7L2!0.65!96.56!TCF7L2;;chr10:63853436..63853442,+!p4@ARID5B!0.65!21.54!ARID5B;;chr1:170632723..170632739,+!p8@PRRX1!0.65!3.50!PRRX1;;chr2:46524537..46524553,+!p1@EPAS1!0.63!384.77!EPAS1;;chr16:54320101..54320125,-!p4@IRX3!0.63!4.88!IRX3;;chr7:44143997..44144008,+!p3@AEBP1!0.63!4.42!AEBP1;;chr3:157824001..157824078,-!p2@SHOX2!0.63!3.31!SHOX2;;chr4:111558135..111558198,-!p2@PITX2!0.63!3.22!PITX2;;chr1:119530857..119530884,-!p4@TBX15!0.63!3.22!TBX15;;chr10:31607811..31607837,+!p6@ZEB1!0.63!3.22!ZEB1;;chr5:142783175..142783297,-!p1@NR3C1!0.62!52.19!NR3C1;;chr3:128206762..128206781,-!p2@GATA2!0.62!23.01!GATA2;;chr13:41635067..41635100,-!p5@ELF1!0.62!6.54!ELF1;;chr15:37392703..37392717,-!p8@MEIS2!0.62!4.79!MEIS2;;chr3:128212033..128212051,-!p1@GATA2!0.62!3.13!GATA2;;chr1:170632115..170632136,+!p9@PRRX1!0.62!3.13!PRRX1;;chr2:191878874..191878938,-!p1@STAT1!0.61!202.23!STAT1;;chr1:164528410..164528428,+!p1@PBX1!0.61!27.52!PBX1;;chr1:200379104..200379128,-!p2@ZNF281!0.61!8.56!ZNF281;;chr10:77161504..77161530,-!p1@ZNF503!0.60!48.42!ZNF503;;chr1:158979872..158979898,+!p3@IFI16!0.60!10.68!IFI16;;chr15:37392576..37392589,-!p12@MEIS2!0.60!3.77!MEIS2;;chr15:37392534..37392562,-!p10@MEIS2!0.60!3.31!MEIS2;;chr1:119530706..119530736,-!p3@TBX15!0.59!2.85!TBX15;;chr12:54410948..54410992,+!p3@HOXC5!0.59!2.85!HOXC5;;chr2:172950227..172950249,+!p2@DLX1!0.59!2.85!DLX1;;chr3:138665969..138665993,-!p2@FOXL2!0.59!2.85!FOXL2;;chr3:141121871..141121885,+!p13@ZBTB38!0.59!2.85!ZBTB38;;chr5:142780237..142780261,-!p7@NR3C1!0.59!2.85!NR3C1;;chr12:48298785..48298828,-!p1@VDR!0.58!17.86!VDR;;chr8:116681409..116681431,-!p2@TRPS1!0.58!8.84!TRPS1;;chr12:48298765..48298783,-!p2@VDR!0.58!6.72!VDR;;chr2:191878812..191878823,-!p2@STAT1!0.58!3.77!STAT1;;chr3:147111505..147111529,+!p6@ZIC1!0.58!2.76!ZIC1;;chr3:147127142..147127168,+!p1@ZIC1!0.58!2.76!ZIC1;;chr12:54402729..54402743,+!p3@HOXC8!0.58!2.76!HOXC8;;chr2:145275162..145275202,-!p2@ZEB2!0.57!19.33!ZEB2;;chr7:42276822..42276895,-!p2@GLI3!0.57!9.67!GLI3;;chr5:139487608..139487663,+!p3@PURA!0.57!6.72!PURA;;chr10:63661437..63661465,+!p2@ARID5B!0.56!62.87!ARID5B;;chr3:178789522..178789564,-!p2@ZMAT3!0.56!24.03!ZMAT3;;chr13:45151403..45151433,-!p5@TSC22D1!0.56!6.63!TSC22D1;;chr2:28618532..28618610,+!p4@FOSL2!0.56!5.06!FOSL2;;chr11:12696071..12696086,+!p3@TEAD1!0.56!3.68!TEAD1;;chr8:72756213..72756243,-!p5@MSC!0.56!3.59!MSC;;chr11:46299443..46299459,+!p4@CREB3L1!0.56!2.67!CREB3L1;;chr12:114845810..114845824,-!p1@TBX5!0.56!2.67!TBX5;;chr12:57914286..57914304,-!p1@DDIT3!0.55!117.27!DDIT3;;chr21:36260980..36261011,-!p1@RUNX1!0.55!93.15!RUNX1;;chr19:13136130..13136165,+!p6@NFIX!0.55!3.59!NFIX;;chr5:3595977..3595999,+!p1@IRX1!0.55!2.58!IRX1;;chr8:93115584..93115642,-!p5@RUNX1T1!0.55!2.58!RUNX1T1;;chr3:24536332..24536358,-!p2@THRB!0.55!2.58!THRB;;chr2:71127699..71127744,+!p1@VAX2!0.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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000057;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0002620;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002097;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002416 | |||
|ffid_belonging_in_development=CL:0000134 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520spinal%2520muscular%2520atrophy%252c%2520donor1.CNhs11074.11555-120C7.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520spinal%2520muscular%2520atrophy%252c%2520donor1.CNhs11074.11555-120C7.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520spinal%2520muscular%2520atrophy%252c%2520donor1.CNhs11074.11555-120C7.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520spinal%2520muscular%2520atrophy%252c%2520donor1.CNhs11074.11555-120C7.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520spinal%2520muscular%2520atrophy%252c%2520donor1.CNhs11074.11555-120C7.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11555-120C7 | |||
|is_a=EFO:0002091;;FF:0000251 | |||
|is_obsolete= | |||
|library_id=CNhs11074 | |||
|library_id_phase_based=2:CNhs11074 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11555 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11555 | |||
|name=Fibroblast - skin spinal muscular atrophy, donor1 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11074,LSID723,release008,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.0191212414416402,0,0,0,0,-0.0869297233215061,0,-0.20144499144121,-0.282403560576942,0,0,0,0.190975487341205,0,0,0,0,0,0,0,0,0,-0.0799347035835476,0,0,0,0,0,-0.0979578962680575,0,0,-0.132956589778862,0,0,0,0,0,0,0,0,0,0,0.07338830676488,0,-0.113204448940105,0,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0.215994075261499,0,0,0,-0.0969923612426051,0,0,-0.023955320448217,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0191212414416402,0,0.019760631540928,0,0,0,0,0.0382424828832804,0,0,-0.0117007141189789,-0.0146030490788059,0.0191212414416402,0.323169315074425,0,0.136149457396536,-0.059792868354426,-0.138477200800895,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.496818962931377,0,0,0,-0.0875274356726945,-0.0558891073597955,0,0,-0.0302099898629903,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0,-0.059792868354426,0,0.136149457396536,0,0,0.0382424828832804,0.0382424828832804,0.0382424828832804,0,0.323169315074425,0,0,0.233560540179631,0.0449608797854786,-0.0206152949136605,-0.143515142523472,0,0,0.00529177382854935,0,0.0382424828832804,0,0.0256710797723414,0,0,0,0.0382424828832804,0,0.5830329346848,0,0.0857369058072216,0,0.07338830676488,0.105901621330139,0,0.0431996302347084,0.0877164763357185,0,-0.0223848420317294,0.193738611059787,0,0,0,0,0.164994776802625,0,0.0152699736027959,0.293993347334812,-0.0306361007616017,0.0510700812638465,-0.00856217600909964,0,0,0,0.112517209593678,0.207771840035332,0,0,0.305899248851868,0.130701944999835,0,0,1.25859838017783,0,-0.0689178689900356,0.070601694171707,0,0,0,0,0,0,0,0,0,0,0,0,0,0.477941163287358,0.014772007571019,0,0,0.0382424828832804,0,0.017350207289791,0,0,-0.157292080695068,0.255392296750808,-0.00230056934392425,-0.298703033530955,0,-0.229001420245033,-0.0606030394850665,0.0040620599310425,-0.0117007141189789,0.406165308749104,0.31641473478375,0,-0.0616080861138347,0.0220021000370617,-0.0204808502525383,-0.0432986646128537,-0.0129534513898698,0.0419546509831625,-0.169957921003584,0,0,0.00091086761766146,0.127601352090924,0,0.0207018775548593,0.258266757877938,-0.087812396130401,0.187763534082089,0.0940406565253202,0.0051829442180167,0.106604598930322,0.16250579081713,0.26142177053677,0.00857822918904895,0.278767831016366,0,0,0,0.0537881859563426,0.0694460941001621,-0.376176598818284,0.00274508326196807,0.0582685938051889,0.0678051963191683,0.0632407586383198,0.0459114887765006,-0.12187109781556,0,0.0382424828832804,0.162409443801896,0.07338830676488,0,0,0.011140827660851,0,-0.129657369076344,0.0666361670175004,-0.0684284973683387,0,-0.0506879673146645,0.0545563453398317,-0.155579039205222,0,-0.0815216062667746,0.236995774776936,-0.0359912802241373,-0.0432997911201112,0,-0.0434056598512411,0.249015510647663,0.0115168178434832,-0.0292060981576117,-0.0584468268118252,-0.124343623728064,-0.0643513141883426,0.0744144325645939,0.410267539000699,0.116377973720948,0.979233763294866,0,0.276000944058166,-0.488522644280319,-0.00555555234510452,-0.0365105062585001,0,0.175768744194035,0,-0.0880212842356012,0,-0.264047989382197,0.0556789464342209,-0.30313991718415,-0.27416543889867,0,-0.0489290020009965,0.282639552691451,0,-0.0610151310644134,0,0,0.153379354900921,-0.0272649332229655,-0.122005463817079,0.108879572193949,0,0.141789013463307,0,0.136149457396536,0.0205084715558315,-0.0710489735771826,0.0382424828832804,-0.144377081726322,-0.128463498748201,-0.320801958900565,-0.0777285905516537,0,0,0.0807289745631092,0,0.480739415465195,-0.500026442487891,0.136149457396536,0.0835248700832619,0.106262258862995,0,0.0989516460531785,0,0,0.038466309296323,0,0.149661250265261,0,0,-0.050765131831978,0,0,0,0.07338830676488,0.0191212414416402,0.0382424828832804,0,0,0,0.0191212414416402,0,0.0298938889908214,-0.158244693461356,-0.01307272596646,0,0,0,0,0,0,0,0,0,0.409061679605454,1.08205220552277,0,0.0131320417201162,0,0,0,0,-0.215723402553475,-0.203236562094724,0.0382424828832804,-0.0936202236143513,0,0,0,0,0.019760631540928,0,0,0,0.0529508106650695,0.0481711642764754,-0.387919449698278,0,0,0,-0.27695440160179,0,0,0.164427064187206,0.042112638722705,-0.12832823507566,0,0,0.277556868914361,0,0.067699133182835,-0.0815818795468414,0,0.101375845865932,0.574395193958427,0.0215047173941012,0,0,-0.261347131789888,0,0.0700591698442712,-0.000541036001370898,-0.0441277400823859,0,0.0591159101920632,0,0,0,0,0,0,0.210060398186965,0.170880302124994,0,0,0,0,0,0,0.239649574360395,0,0,0,0.083617903146023,-0.0922240566585104,0.07338830676488,0,0,0,0,0,0,-0.0241060230789031,-0.126135882840681,0,0,0,0,0,0,0,0,-0.0782372324291163,0,0,0,0,0,-0.0969923612426051,0,0,0,0.0382424828832804,-0.564807121153884,0,0,-0.171460510863375,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0174174647053084,-0.279377335436949,0,0,0,0,0,0,0,-0.20144499144121,0,0,0,0,-0.0756418908256968,0,0,0,0.254792215560595,0,-0.0869297233215061,0,0,0,0,0,0.0684676568136192,0,0,0,0,0,0,0,0,0,0,0,0.0191212414416402,0,0,0,0.562665054162792,0.0208847817919349,0.0382424828832804,0.0247953908666888,0,0,0.141562383544314,0,0,0,0,0,0,0.00535372935391295,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0332166848931799,0,0,0,0,0.136149457396536,0,0,-0.0979578962680575,0,0.300018583473329,-0.0729115683588859,0,0,0,0,0,0,0.246118117746202,0.393686685719386,0.0141736524229621,0,0,0,0.125408727692421,0.215994075261499,0,0,0,0.413962028046294,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0799347035835476,0,0,0,0,0,0,0,0,0,0,0,0,0.068074728698268,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.105901621330139,0,0,0,0,0,0,0.0382424828832804,-0.0148901218337763,0.0382424828832804,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0800184682686384,0,0,0,-0.0769367722605072,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.07338830676488,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.269279409553858,0,0,0,0,0,0,0,0,0.07338830676488,0,0,0,0,-0.0482220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| |||
|rna_box=120 | |||
|rna_catalog_number=custom | |||
|rna_concentration=0.881 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-ethanol-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=1.9 | |||
|rna_od260/280=2.12 | |||
|rna_position=C7 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=120C7 | |||
|rna_weight_ug=118.9053 | |||
|sample_age=3 year old child | |||
|sample_category=primary cells | |||
|sample_cell_catalog=N/A | |||
|sample_cell_line= | |||
|sample_cell_lot=GM03813 | |||
|sample_cell_type=fibroblast | |||
|sample_collaboration=Splicing (contact: Al Forrest) | |||
|sample_company=Coriell | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=SPINAL MUSCULAR ATROPHY I; SMA1 | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=C | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;8.07261400065504e-216!GO:0043226;organelle;2.81324215794875e-172!GO:0043229;intracellular organelle;7.03903966639067e-172!GO:0043231;intracellular membrane-bound organelle;2.03829783862358e-170!GO:0043227;membrane-bound organelle;3.14418034017271e-170!GO:0005737;cytoplasm;1.86667721920394e-165!GO:0044444;cytoplasmic part;1.56976836537826e-119!GO:0044422;organelle part;7.85771306738794e-113!GO:0044446;intracellular organelle part;2.21783644557124e-111!GO:0044238;primary metabolic process;2.27934175109789e-79!GO:0044237;cellular metabolic process;6.33433609916302e-79!GO:0032991;macromolecular complex;1.73052395210752e-78!GO:0043170;macromolecule metabolic process;5.20358263491755e-78!GO:0005515;protein binding;5.47461446026385e-75!GO:0030529;ribonucleoprotein complex;5.25234491487198e-74!GO:0005634;nucleus;2.95435171976622e-67!GO:0043233;organelle lumen;1.49622975642945e-63!GO:0031974;membrane-enclosed lumen;1.49622975642945e-63!GO:0044428;nuclear part;1.05427926538776e-60!GO:0003723;RNA binding;2.23831307972115e-60!GO:0005739;mitochondrion;1.05834762040023e-54!GO:0019538;protein metabolic process;7.25054684114783e-46!GO:0016043;cellular component organization and biogenesis;3.27888286766337e-45!GO:0005840;ribosome;6.29260772589785e-44!GO:0033036;macromolecule localization;1.02812506933291e-43!GO:0015031;protein transport;1.98282081335004e-43!GO:0010467;gene expression;2.78368593951818e-43!GO:0006412;translation;3.87334902256836e-43!GO:0043283;biopolymer metabolic process;2.24663580286476e-42!GO:0031090;organelle membrane;3.69370712696993e-42!GO:0006396;RNA processing;2.0587642065324e-41!GO:0044260;cellular macromolecule metabolic process;1.15822065464412e-40!GO:0008104;protein localization;1.84005897703125e-40!GO:0045184;establishment of protein localization;8.77654522667854e-40!GO:0044267;cellular protein metabolic process;1.11202292688814e-39!GO:0003735;structural constituent of ribosome;7.31006554736381e-39!GO:0043234;protein complex;4.22476755178715e-38!GO:0031981;nuclear lumen;5.50192916429613e-38!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.74927719655038e-37!GO:0044429;mitochondrial part;6.99760888745659e-36!GO:0016071;mRNA metabolic process;2.69683023965693e-35!GO:0005829;cytosol;8.15852752864015e-34!GO:0046907;intracellular transport;1.24243554100467e-33!GO:0033279;ribosomal subunit;1.24243554100467e-33!GO:0009059;macromolecule biosynthetic process;8.78127214346788e-33!GO:0008380;RNA splicing;1.90267482458905e-32!GO:0009058;biosynthetic process;2.63297679584171e-32!GO:0031967;organelle envelope;4.9181248823167e-32!GO:0031975;envelope;8.60328197380434e-32!GO:0044249;cellular biosynthetic process;2.75496915197115e-31!GO:0006397;mRNA processing;1.31877202555169e-30!GO:0006886;intracellular protein transport;2.65194124668822e-29!GO:0065003;macromolecular complex assembly;6.7166576069827e-28!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.83044901247233e-25!GO:0022607;cellular component assembly;5.55634493342073e-25!GO:0022613;ribonucleoprotein complex biogenesis and assembly;6.96111903755813e-25!GO:0005654;nucleoplasm;2.07565695935358e-24!GO:0006996;organelle organization and biogenesis;2.22014756294284e-24!GO:0003676;nucleic acid binding;2.42658526675326e-23!GO:0005681;spliceosome;7.08785326171319e-23!GO:0005740;mitochondrial envelope;1.06167251086734e-22!GO:0043228;non-membrane-bound organelle;3.95185381370168e-22!GO:0043232;intracellular non-membrane-bound organelle;3.95185381370168e-22!GO:0031966;mitochondrial membrane;1.21615911011154e-21!GO:0019866;organelle inner membrane;1.93572621426521e-21!GO:0016070;RNA metabolic process;7.44703990190645e-21!GO:0051649;establishment of cellular localization;1.95288716334864e-20!GO:0051641;cellular localization;2.06288676625029e-20!GO:0005743;mitochondrial inner membrane;4.40408548652184e-20!GO:0044451;nucleoplasm part;4.84869132103276e-20!GO:0044445;cytosolic part;1.81616038778777e-19!GO:0006457;protein folding;2.33349747559136e-19!GO:0006119;oxidative phosphorylation;5.67145691961849e-19!GO:0048770;pigment granule;1.18619274543637e-18!GO:0042470;melanosome;1.18619274543637e-18!GO:0005783;endoplasmic reticulum;2.16536264767669e-18!GO:0015935;small ribosomal subunit;4.24252770475108e-18!GO:0000166;nucleotide binding;5.98253401075126e-18!GO:0016462;pyrophosphatase activity;1.04744351551765e-17!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.16305887027515e-17!GO:0016817;hydrolase activity, acting on acid anhydrides;1.8534189545771e-17!GO:0008134;transcription factor binding;3.10124691342293e-17!GO:0022618;protein-RNA complex assembly;3.48786812226519e-17!GO:0016874;ligase activity;3.98588320760209e-17!GO:0017111;nucleoside-triphosphatase activity;3.98588320760209e-17!GO:0012505;endomembrane system;4.84116085509528e-17!GO:0006512;ubiquitin cycle;9.222978759375e-17!GO:0006259;DNA metabolic process;9.78770039313345e-17!GO:0044455;mitochondrial membrane part;1.57433549337521e-16!GO:0015934;large ribosomal subunit;1.58656447751039e-16!GO:0005794;Golgi apparatus;5.3601071990234e-16!GO:0031980;mitochondrial lumen;8.45756117087218e-16!GO:0005759;mitochondrial matrix;8.45756117087218e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;8.83869556030643e-16!GO:0048193;Golgi vesicle transport;1.87324891610997e-15!GO:0019941;modification-dependent protein catabolic process;1.87621004868172e-15!GO:0043632;modification-dependent macromolecule catabolic process;1.87621004868172e-15!GO:0006511;ubiquitin-dependent protein catabolic process;2.43662253136079e-15!GO:0044257;cellular protein catabolic process;3.07985761789909e-15!GO:0044265;cellular macromolecule catabolic process;3.77660161589981e-15!GO:0043285;biopolymer catabolic process;5.08391466659302e-15!GO:0008135;translation factor activity, nucleic acid binding;7.38140220786389e-15!GO:0044432;endoplasmic reticulum part;1.28136477732934e-14!GO:0005746;mitochondrial respiratory chain;3.68434366478176e-14!GO:0005730;nucleolus;3.74535492962613e-14!GO:0006605;protein targeting;3.7681173946587e-14!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;5.97518750981703e-14!GO:0000502;proteasome complex (sensu Eukaryota);9.85771598770057e-14!GO:0051082;unfolded protein binding;1.02204700800524e-13!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.19842822565779e-13!GO:0030163;protein catabolic process;1.2880985851012e-13!GO:0009057;macromolecule catabolic process;1.88638044574323e-13!GO:0016192;vesicle-mediated transport;2.4105155059031e-13!GO:0051186;cofactor metabolic process;3.42061570536729e-13!GO:0050136;NADH dehydrogenase (quinone) activity;1.37539247953836e-12!GO:0003954;NADH dehydrogenase activity;1.37539247953836e-12!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.37539247953836e-12!GO:0005761;mitochondrial ribosome;1.79797976539569e-12!GO:0000313;organellar ribosome;1.79797976539569e-12!GO:0032553;ribonucleotide binding;2.48268295866316e-12!GO:0032555;purine ribonucleotide binding;2.48268295866316e-12!GO:0003712;transcription cofactor activity;2.52656876333597e-12!GO:0017076;purine nucleotide binding;2.65368238833418e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);5.38353927455731e-12!GO:0050794;regulation of cellular process;8.58863427376023e-12!GO:0005793;ER-Golgi intermediate compartment;9.04637610328418e-12!GO:0003743;translation initiation factor activity;1.48636193759936e-11!GO:0044248;cellular catabolic process;1.63217763272266e-11!GO:0007049;cell cycle;1.77336964833878e-11!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.18982181477964e-11!GO:0000398;nuclear mRNA splicing, via spliceosome;2.49778949772186e-11!GO:0000375;RNA splicing, via transesterification reactions;2.49778949772186e-11!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.49778949772186e-11!GO:0006413;translational initiation;4.34081336888803e-11!GO:0042775;organelle ATP synthesis coupled electron transport;5.6833238036133e-11!GO:0042773;ATP synthesis coupled electron transport;5.6833238036133e-11!GO:0030964;NADH dehydrogenase complex (quinone);6.87018275955453e-11!GO:0045271;respiratory chain complex I;6.87018275955453e-11!GO:0005747;mitochondrial respiratory chain complex I;6.87018275955453e-11!GO:0043412;biopolymer modification;1.10076001027485e-10!GO:0006974;response to DNA damage stimulus;1.17269541835492e-10!GO:0016604;nuclear body;1.61458222644518e-10!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.77616070832805e-10!GO:0006446;regulation of translational initiation;2.26463435795684e-10!GO:0006732;coenzyme metabolic process;2.32483046664342e-10!GO:0008639;small protein conjugating enzyme activity;3.77306204180866e-10!GO:0005635;nuclear envelope;5.59969285000292e-10!GO:0004842;ubiquitin-protein ligase activity;6.62766478618782e-10!GO:0009055;electron carrier activity;6.75669719408767e-10!GO:0006913;nucleocytoplasmic transport;8.09058456836178e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;8.38940474618985e-10!GO:0019787;small conjugating protein ligase activity;8.61442930559745e-10!GO:0006464;protein modification process;1.32142250104695e-09!GO:0012501;programmed cell death;1.34851390399555e-09!GO:0006366;transcription from RNA polymerase II promoter;1.52893505669845e-09!GO:0051169;nuclear transport;1.53264073542198e-09!GO:0031965;nuclear membrane;1.68710801791178e-09!GO:0048523;negative regulation of cellular process;2.18548054427571e-09!GO:0005789;endoplasmic reticulum membrane;2.29350017076372e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.41844790180449e-09!GO:0008565;protein transporter activity;2.8945793006164e-09!GO:0009259;ribonucleotide metabolic process;2.97266495924555e-09!GO:0005524;ATP binding;3.40684690481237e-09!GO:0006915;apoptosis;3.46793564304378e-09!GO:0016607;nuclear speck;3.55428310363371e-09!GO:0032559;adenyl ribonucleotide binding;4.97599074229347e-09!GO:0006461;protein complex assembly;6.35595680681886e-09!GO:0030554;adenyl nucleotide binding;6.57785041505496e-09!GO:0008219;cell death;9.0428935855752e-09!GO:0016265;death;9.0428935855752e-09!GO:0006163;purine nucleotide metabolic process;1.03038645466444e-08!GO:0009150;purine ribonucleotide metabolic process;1.04576601230158e-08!GO:0016881;acid-amino acid ligase activity;1.05539738292043e-08!GO:0006888;ER to Golgi vesicle-mediated transport;1.1489504498412e-08!GO:0042254;ribosome biogenesis and assembly;1.1489504498412e-08!GO:0050789;regulation of biological process;1.38789041117496e-08!GO:0022402;cell cycle process;1.68722876744178e-08!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.91590092643803e-08!GO:0003924;GTPase activity;2.22214896536937e-08!GO:0004386;helicase activity;2.45232208844308e-08!GO:0042623;ATPase activity, coupled;2.45232208844308e-08!GO:0016887;ATPase activity;2.45678171483434e-08!GO:0043687;post-translational protein modification;2.73484226768373e-08!GO:0009260;ribonucleotide biosynthetic process;3.12692396340066e-08!GO:0030120;vesicle coat;3.32406547836489e-08!GO:0030662;coated vesicle membrane;3.32406547836489e-08!GO:0009152;purine ribonucleotide biosynthetic process;3.32406547836489e-08!GO:0006164;purine nucleotide biosynthetic process;3.42083131562402e-08!GO:0009060;aerobic respiration;3.89588981546942e-08!GO:0005768;endosome;3.94972538829209e-08!GO:0044453;nuclear membrane part;4.24957726768066e-08!GO:0045333;cellular respiration;5.17723411764371e-08!GO:0005788;endoplasmic reticulum lumen;5.64929456941893e-08!GO:0006281;DNA repair;5.70347400721155e-08!GO:0009719;response to endogenous stimulus;6.33191610506289e-08!GO:0017038;protein import;7.50124811826473e-08!GO:0009199;ribonucleoside triphosphate metabolic process;7.50293661056826e-08!GO:0006399;tRNA metabolic process;7.60021901166057e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;8.07928338260974e-08!GO:0008026;ATP-dependent helicase activity;8.11312443374724e-08!GO:0048519;negative regulation of biological process;8.48818698237289e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;8.5755169135062e-08!GO:0009144;purine nucleoside triphosphate metabolic process;8.5755169135062e-08!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;9.66244225308859e-08!GO:0004812;aminoacyl-tRNA ligase activity;9.66244225308859e-08!GO:0016875;ligase activity, forming carbon-oxygen bonds;9.66244225308859e-08!GO:0009141;nucleoside triphosphate metabolic process;1.30627839257626e-07!GO:0048475;coated membrane;1.33205619919825e-07!GO:0030117;membrane coat;1.33205619919825e-07!GO:0043038;amino acid activation;1.49281610600457e-07!GO:0006418;tRNA aminoacylation for protein translation;1.49281610600457e-07!GO:0043039;tRNA aminoacylation;1.49281610600457e-07!GO:0051246;regulation of protein metabolic process;2.08708571165484e-07!GO:0015986;ATP synthesis coupled proton transport;2.2322855514187e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.2322855514187e-07!GO:0019222;regulation of metabolic process;2.99368393355467e-07!GO:0065002;intracellular protein transport across a membrane;3.97655780149737e-07!GO:0009142;nucleoside triphosphate biosynthetic process;4.25809876206572e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;4.25809876206572e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;4.93758055538344e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;4.93758055538344e-07!GO:0046034;ATP metabolic process;5.87199613421467e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;6.07198885900747e-07!GO:0006325;establishment and/or maintenance of chromatin architecture;7.05424720423235e-07!GO:0000074;regulation of progression through cell cycle;7.9049010979743e-07!GO:0051726;regulation of cell cycle;8.05649083411044e-07!GO:0003714;transcription corepressor activity;8.12941042298462e-07!GO:0006099;tricarboxylic acid cycle;8.65275329611263e-07!GO:0046356;acetyl-CoA catabolic process;8.65275329611263e-07!GO:0051187;cofactor catabolic process;9.35152963505734e-07!GO:0019829;cation-transporting ATPase activity;1.1019777075295e-06!GO:0006916;anti-apoptosis;1.2396665030526e-06!GO:0031252;leading edge;1.30320064335998e-06!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.34326969064154e-06!GO:0009109;coenzyme catabolic process;1.41613243229042e-06!GO:0009056;catabolic process;1.41814391368159e-06!GO:0000278;mitotic cell cycle;1.41814391368159e-06!GO:0043069;negative regulation of programmed cell death;1.42213233720198e-06!GO:0000151;ubiquitin ligase complex;1.42663956512367e-06!GO:0016491;oxidoreductase activity;1.48617246536837e-06!GO:0030036;actin cytoskeleton organization and biogenesis;1.61966042589344e-06!GO:0005643;nuclear pore;1.68760658727813e-06!GO:0015078;hydrogen ion transmembrane transporter activity;1.70262086581886e-06!GO:0006323;DNA packaging;1.73496259616951e-06!GO:0031324;negative regulation of cellular metabolic process;1.92067409242338e-06!GO:0044431;Golgi apparatus part;1.95840110926541e-06!GO:0051276;chromosome organization and biogenesis;2.13330948411595e-06!GO:0043067;regulation of programmed cell death;2.41657781078313e-06!GO:0050657;nucleic acid transport;2.45093497243085e-06!GO:0051236;establishment of RNA localization;2.45093497243085e-06!GO:0050658;RNA transport;2.45093497243085e-06!GO:0008361;regulation of cell size;2.48499712268629e-06!GO:0032446;protein modification by small protein conjugation;2.53583066355666e-06!GO:0005798;Golgi-associated vesicle;2.6667997696701e-06!GO:0006403;RNA localization;2.72985012665835e-06!GO:0043066;negative regulation of apoptosis;2.77785973153381e-06!GO:0042981;regulation of apoptosis;2.81923810671332e-06!GO:0006754;ATP biosynthetic process;2.94970198888347e-06!GO:0006753;nucleoside phosphate metabolic process;2.94970198888347e-06!GO:0051789;response to protein stimulus;2.96798653306951e-06!GO:0006986;response to unfolded protein;2.96798653306951e-06!GO:0016567;protein ubiquitination;3.38203748466899e-06!GO:0016049;cell growth;3.49997992378182e-06!GO:0016564;transcription repressor activity;3.51586661238201e-06!GO:0006084;acetyl-CoA metabolic process;3.86903574994899e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;3.87394273948706e-06!GO:0030532;small nuclear ribonucleoprotein complex;4.44990906504343e-06!GO:0005839;proteasome core complex (sensu Eukaryota);4.57449756381566e-06!GO:0051188;cofactor biosynthetic process;4.60857333334576e-06!GO:0016469;proton-transporting two-sector ATPase complex;5.61394955139662e-06!GO:0044440;endosomal part;6.14910512531385e-06!GO:0010008;endosome membrane;6.14910512531385e-06!GO:0003713;transcription coactivator activity;6.37410131482873e-06!GO:0031988;membrane-bound vesicle;6.563213566406e-06!GO:0005525;GTP binding;7.12392974755732e-06!GO:0016023;cytoplasmic membrane-bound vesicle;7.57658559784115e-06!GO:0000245;spliceosome assembly;8.02519694111995e-06!GO:0006613;cotranslational protein targeting to membrane;9.59577533000995e-06!GO:0007005;mitochondrion organization and biogenesis;9.68373087852795e-06!GO:0051170;nuclear import;1.05257733196787e-05!GO:0009117;nucleotide metabolic process;1.06216694923997e-05!GO:0045786;negative regulation of progression through cell cycle;1.15418264689507e-05!GO:0005667;transcription factor complex;1.19239257787215e-05!GO:0003697;single-stranded DNA binding;1.20450494891503e-05!GO:0065004;protein-DNA complex assembly;1.40443265549514e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.45438214460943e-05!GO:0046930;pore complex;1.45657415325965e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.60585351118944e-05!GO:0006606;protein import into nucleus;1.60585351118944e-05!GO:0045259;proton-transporting ATP synthase complex;1.62320747459487e-05!GO:0043566;structure-specific DNA binding;1.62741501563322e-05!GO:0009892;negative regulation of metabolic process;1.70454594352416e-05!GO:0003724;RNA helicase activity;1.7246182900318e-05!GO:0031982;vesicle;1.97750484601303e-05!GO:0030029;actin filament-based process;2.11540326509292e-05!GO:0001558;regulation of cell growth;2.14629016318999e-05!GO:0004298;threonine endopeptidase activity;2.27049807724284e-05!GO:0031410;cytoplasmic vesicle;2.57861090032029e-05!GO:0005769;early endosome;2.64992054957289e-05!GO:0006364;rRNA processing;2.94448396574325e-05!GO:0016563;transcription activator activity;3.33977384251138e-05!GO:0030133;transport vesicle;3.38815867100077e-05!GO:0005770;late endosome;3.44426398164643e-05!GO:0015980;energy derivation by oxidation of organic compounds;3.66706585728108e-05!GO:0032561;guanyl ribonucleotide binding;3.67156685952837e-05!GO:0019001;guanyl nucleotide binding;3.67156685952837e-05!GO:0030867;rough endoplasmic reticulum membrane;3.78634875867871e-05!GO:0016853;isomerase activity;3.93420573237171e-05!GO:0005773;vacuole;4.01726867058529e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;4.33871351511791e-05!GO:0016072;rRNA metabolic process;4.38438639447621e-05!GO:0006752;group transfer coenzyme metabolic process;4.52689055814173e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;4.72627554036928e-05!GO:0065007;biological regulation;4.92555558223761e-05!GO:0016568;chromatin modification;5.46853073473168e-05!GO:0051028;mRNA transport;5.72827074265585e-05!GO:0015630;microtubule cytoskeleton;6.27411759429357e-05!GO:0009108;coenzyme biosynthetic process;6.43469892448087e-05!GO:0005791;rough endoplasmic reticulum;6.44496428834265e-05!GO:0016859;cis-trans isomerase activity;6.66777243070128e-05!GO:0019843;rRNA binding;6.83325617359972e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;7.08865069040782e-05!GO:0031323;regulation of cellular metabolic process;7.22270234062516e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;8.01423370626499e-05!GO:0005905;coated pit;9.03381100066099e-05!GO:0016481;negative regulation of transcription;9.29280211990841e-05!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;0.000102363831829528!GO:0005694;chromosome;0.00010882473060131!GO:0045454;cell redox homeostasis;0.00010882473060131!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.000117891856461897!GO:0019899;enzyme binding;0.000117891856461897!GO:0006260;DNA replication;0.000119893062764922!GO:0000139;Golgi membrane;0.000127743380169213!GO:0007010;cytoskeleton organization and biogenesis;0.000161180455266285!GO:0005762;mitochondrial large ribosomal subunit;0.000164712828949075!GO:0000315;organellar large ribosomal subunit;0.000164712828949075!GO:0008654;phospholipid biosynthetic process;0.000172680894134545!GO:0043021;ribonucleoprotein binding;0.000188416301792695!GO:0006091;generation of precursor metabolites and energy;0.00019898735923909!GO:0005813;centrosome;0.000200705446455863!GO:0006350;transcription;0.000226698283614452!GO:0030663;COPI coated vesicle membrane;0.000239673091655277!GO:0030126;COPI vesicle coat;0.000239673091655277!GO:0006333;chromatin assembly or disassembly;0.000253835840656002!GO:0006612;protein targeting to membrane;0.000258988444593914!GO:0000323;lytic vacuole;0.000271560287329379!GO:0005764;lysosome;0.000271560287329379!GO:0016310;phosphorylation;0.000295075178729573!GO:0008092;cytoskeletal protein binding;0.000320680222054818!GO:0033116;ER-Golgi intermediate compartment membrane;0.000351145523998341!GO:0043623;cellular protein complex assembly;0.000363340093129154!GO:0006793;phosphorus metabolic process;0.000421525761948484!GO:0006796;phosphate metabolic process;0.000421525761948484!GO:0022403;cell cycle phase;0.000422324075383734!GO:0048522;positive regulation of cellular process;0.000424061277071147!GO:0006891;intra-Golgi vesicle-mediated transport;0.000432555290238602!GO:0005815;microtubule organizing center;0.000445227737584176!GO:0008250;oligosaccharyl transferase complex;0.00045271513686514!GO:0051427;hormone receptor binding;0.000472441875504489!GO:0005885;Arp2/3 protein complex;0.000481340368618646!GO:0016787;hydrolase activity;0.000502643605473836!GO:0010468;regulation of gene expression;0.00050592328889306!GO:0030137;COPI-coated vesicle;0.000527275015159627!GO:0005048;signal sequence binding;0.000558353617317245!GO:0004576;oligosaccharyl transferase activity;0.000640435542624248!GO:0000314;organellar small ribosomal subunit;0.000640435542624248!GO:0005763;mitochondrial small ribosomal subunit;0.000640435542624248!GO:0031968;organelle outer membrane;0.000651915538081822!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000657665382762282!GO:0044427;chromosomal part;0.000670959360765866!GO:0051168;nuclear export;0.000751150402164875!GO:0008186;RNA-dependent ATPase activity;0.000781767045787476!GO:0019867;outer membrane;0.000823220332350479!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000826650276544236!GO:0035257;nuclear hormone receptor binding;0.000860971734518932!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000876283670496675!GO:0030027;lamellipodium;0.000898348579010923!GO:0007243;protein kinase cascade;0.000900973731427055!GO:0000087;M phase of mitotic cell cycle;0.000902239803695469!GO:0016779;nucleotidyltransferase activity;0.000962549109334919!GO:0007050;cell cycle arrest;0.000989409514073061!GO:0051301;cell division;0.000997463043668209!GO:0051920;peroxiredoxin activity;0.00102852255551094!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00104490773449719!GO:0016363;nuclear matrix;0.0010469208245789!GO:0007067;mitosis;0.00117579985161565!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00119170626414106!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.00144039477423565!GO:0004177;aminopeptidase activity;0.00144321588625504!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0014656752592286!GO:0000785;chromatin;0.00158043753587031!GO:0051252;regulation of RNA metabolic process;0.00164153515579116!GO:0005741;mitochondrial outer membrane;0.00167570209185557!GO:0016740;transferase activity;0.00172270151234864!GO:0018196;peptidyl-asparagine modification;0.00176469310400083!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00176469310400083!GO:0003729;mRNA binding;0.0017885961535118!GO:0051329;interphase of mitotic cell cycle;0.00179868460003373!GO:0007264;small GTPase mediated signal transduction;0.0018254721748038!GO:0048500;signal recognition particle;0.00186524564060131!GO:0040008;regulation of growth;0.00188069463434018!GO:0043284;biopolymer biosynthetic process;0.00188069463434018!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00189212671469896!GO:0001726;ruffle;0.001898011445639!GO:0003899;DNA-directed RNA polymerase activity;0.00200055700335845!GO:0044262;cellular carbohydrate metabolic process;0.00202574850790228!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00208466745829341!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00208466745829341!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00208466745829341!GO:0046489;phosphoinositide biosynthetic process;0.00208872264869458!GO:0004004;ATP-dependent RNA helicase activity;0.00212990225089623!GO:0046474;glycerophospholipid biosynthetic process;0.00213526061123984!GO:0030658;transport vesicle membrane;0.00213918225915297!GO:0006414;translational elongation;0.00215478096353897!GO:0030521;androgen receptor signaling pathway;0.00221324239436227!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00225715237586414!GO:0043681;protein import into mitochondrion;0.00249914580933173!GO:0048471;perinuclear region of cytoplasm;0.00255373300164709!GO:0006402;mRNA catabolic process;0.00323239513199809!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.00337568259980468!GO:0045892;negative regulation of transcription, DNA-dependent;0.00340448050022187!GO:0003690;double-stranded DNA binding;0.00351300359215288!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00351735171631802!GO:0030134;ER to Golgi transport vesicle;0.00415402544458838!GO:0030132;clathrin coat of coated pit;0.00425077660532969!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00445278648922003!GO:0045047;protein targeting to ER;0.00445278648922003!GO:0032774;RNA biosynthetic process;0.00462188747209369!GO:0006383;transcription from RNA polymerase III promoter;0.00467461235648071!GO:0043488;regulation of mRNA stability;0.0046913184869331!GO:0043487;regulation of RNA stability;0.0046913184869331!GO:0031072;heat shock protein binding;0.0046986167751037!GO:0051128;regulation of cellular component organization and biogenesis;0.00479983886849878!GO:0003746;translation elongation factor activity;0.00484700691921895!GO:0016044;membrane organization and biogenesis;0.0048621168655557!GO:0009165;nucleotide biosynthetic process;0.00492670867697588!GO:0030127;COPII vesicle coat;0.00492670867697588!GO:0012507;ER to Golgi transport vesicle membrane;0.00492670867697588!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0049986756750617!GO:0015399;primary active transmembrane transporter activity;0.0049986756750617!GO:0008154;actin polymerization and/or depolymerization;0.00504766440300779!GO:0051325;interphase;0.00504950759336838!GO:0006351;transcription, DNA-dependent;0.00509753029694482!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00518117877977714!GO:0006352;transcription initiation;0.00518117877977714!GO:0051087;chaperone binding;0.005191098921183!GO:0006334;nucleosome assembly;0.00521765191862585!GO:0003711;transcription elongation regulator activity;0.00523060798552084!GO:0030041;actin filament polymerization;0.00529307099262515!GO:0031901;early endosome membrane;0.00546886330426548!GO:0006626;protein targeting to mitochondrion;0.00636898614658692!GO:0005869;dynactin complex;0.00639484937650318!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00647836281087524!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00656779103939161!GO:0030660;Golgi-associated vesicle membrane;0.00656837345836803!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0065914285144823!GO:0008312;7S RNA binding;0.00673789671524484!GO:0030118;clathrin coat;0.00682756001277292!GO:0000049;tRNA binding;0.00686848355881057!GO:0045941;positive regulation of transcription;0.00691464679996909!GO:0006289;nucleotide-excision repair;0.00707180264190221!GO:0017166;vinculin binding;0.00722942621725074!GO:0030880;RNA polymerase complex;0.00748794682076789!GO:0030833;regulation of actin filament polymerization;0.00749372109712716!GO:0045893;positive regulation of transcription, DNA-dependent;0.00753372078473814!GO:0045045;secretory pathway;0.00758795854741933!GO:0051287;NAD binding;0.00758795854741933!GO:0050811;GABA receptor binding;0.00814472452298316!GO:0006740;NADPH regeneration;0.00824479335775692!GO:0006098;pentose-phosphate shunt;0.00824479335775692!GO:0046914;transition metal ion binding;0.00824479335775692!GO:0000059;protein import into nucleus, docking;0.00869815213492489!GO:0045449;regulation of transcription;0.00883346430237772!GO:0006509;membrane protein ectodomain proteolysis;0.00883346430237772!GO:0033619;membrane protein proteolysis;0.00883346430237772!GO:0048487;beta-tubulin binding;0.00891528477762153!GO:0003684;damaged DNA binding;0.00891604727017909!GO:0006892;post-Golgi vesicle-mediated transport;0.00900610808432657!GO:0008047;enzyme activator activity;0.00905350209985134!GO:0016197;endosome transport;0.00917658659719482!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00933009546986546!GO:0001527;microfibril;0.00941534784259367!GO:0006354;RNA elongation;0.00960333801451793!GO:0016251;general RNA polymerase II transcription factor activity;0.00962487669028735!GO:0008180;signalosome;0.00964083659074651!GO:0031497;chromatin assembly;0.00967273013212615!GO:0032984;macromolecular complex disassembly;0.0100995598506434!GO:0031625;ubiquitin protein ligase binding;0.0104635980689785!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0108885870850877!GO:0008139;nuclear localization sequence binding;0.0110049598516663!GO:0015631;tubulin binding;0.0111322620771275!GO:0006839;mitochondrial transport;0.0111728168597645!GO:0007179;transforming growth factor beta receptor signaling pathway;0.0111992367775993!GO:0006497;protein amino acid lipidation;0.0111992367775993!GO:0051540;metal cluster binding;0.0111992367775993!GO:0051536;iron-sulfur cluster binding;0.0111992367775993!GO:0022408;negative regulation of cell-cell adhesion;0.011238544708259!GO:0050681;androgen receptor binding;0.0120322455526714!GO:0007006;mitochondrial membrane organization and biogenesis;0.0121486362713729!GO:0048518;positive regulation of biological process;0.0121980896108724!GO:0035258;steroid hormone receptor binding;0.012883512652806!GO:0046483;heterocycle metabolic process;0.0137841565519022!GO:0030518;steroid hormone receptor signaling pathway;0.013897591016286!GO:0009116;nucleoside metabolic process;0.013897591016286!GO:0000209;protein polyubiquitination;0.0141039433384027!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0141340641426129!GO:0000428;DNA-directed RNA polymerase complex;0.0141340641426129!GO:0048468;cell development;0.0144403050700231!GO:0000339;RNA cap binding;0.0145127561773021!GO:0043433;negative regulation of transcription factor activity;0.0145584815827627!GO:0045792;negative regulation of cell size;0.0150225431129247!GO:0006401;RNA catabolic process;0.0150911251611714!GO:0043624;cellular protein complex disassembly;0.0153164750610032!GO:0009967;positive regulation of signal transduction;0.0153834278274668!GO:0008022;protein C-terminus binding;0.0154786199483401!GO:0005583;fibrillar collagen;0.0155032265167259!GO:0051493;regulation of cytoskeleton organization and biogenesis;0.0155480713614224!GO:0033043;regulation of organelle organization and biogenesis;0.0155480713614224!GO:0031124;mRNA 3'-end processing;0.0155674167649335!GO:0001953;negative regulation of cell-matrix adhesion;0.0156352774909316!GO:0030384;phosphoinositide metabolic process;0.0161848583727795!GO:0031543;peptidyl-proline dioxygenase activity;0.0163671584770777!GO:0000279;M phase;0.0163671584770777!GO:0000082;G1/S transition of mitotic cell cycle;0.0165676405577607!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0171039074176781!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0171039074176781!GO:0009112;nucleobase metabolic process;0.017128023090082!GO:0065009;regulation of a molecular function;0.0175725159083856!GO:0005862;muscle thin filament tropomyosin;0.0178841496248585!GO:0003779;actin binding;0.0178946155574253!GO:0042802;identical protein binding;0.0181458244423135!GO:0006650;glycerophospholipid metabolic process;0.0181515597641048!GO:0001952;regulation of cell-matrix adhesion;0.0183284214665947!GO:0031529;ruffle organization and biogenesis;0.0184791974453718!GO:0043241;protein complex disassembly;0.0185080068380187!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0185080068380187!GO:0015002;heme-copper terminal oxidase activity;0.0185080068380187!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0185080068380187!GO:0004129;cytochrome-c oxidase activity;0.0185080068380187!GO:0030176;integral to endoplasmic reticulum membrane;0.0189086605224774!GO:0008270;zinc ion binding;0.0190001812601137!GO:0030308;negative regulation of cell growth;0.0191611540610404!GO:0003702;RNA polymerase II transcription factor activity;0.020010661457151!GO:0006506;GPI anchor biosynthetic process;0.0202408210238091!GO:0008064;regulation of actin polymerization and/or depolymerization;0.0202408210238091!GO:0033673;negative regulation of kinase activity;0.0206750949555947!GO:0006469;negative regulation of protein kinase activity;0.0206750949555947!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.0206750949555947!GO:0003756;protein disulfide isomerase activity;0.0217058774477741!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0217058774477741!GO:0043022;ribosome binding;0.0217916709404!GO:0017015;regulation of transforming growth factor beta receptor signaling pathway;0.0221179893355526!GO:0030125;clathrin vesicle coat;0.0226945640044728!GO:0030665;clathrin coated vesicle membrane;0.0226945640044728!GO:0005595;collagen type XII;0.0227539631823565!GO:0016272;prefoldin complex;0.0230820913190889!GO:0050662;coenzyme binding;0.0233191668557431!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0238191078049958!GO:0030032;lamellipodium biogenesis;0.0238376228777499!GO:0005684;U2-dependent spliceosome;0.0242669236082952!GO:0006302;double-strand break repair;0.0244147410555869!GO:0031418;L-ascorbic acid binding;0.0251218349060644!GO:0051539;4 iron, 4 sulfur cluster binding;0.0258813519243855!GO:0043492;ATPase activity, coupled to movement of substances;0.0260240400221948!GO:0030119;AP-type membrane coat adaptor complex;0.0261491295109005!GO:0015992;proton transport;0.0262227606719315!GO:0005832;chaperonin-containing T-complex;0.0262227606719315!GO:0006376;mRNA splice site selection;0.0266885595270613!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0266885595270613!GO:0006979;response to oxidative stress;0.0267287775014455!GO:0035035;histone acetyltransferase binding;0.0267379466383194!GO:0044420;extracellular matrix part;0.0267571651777689!GO:0007021;tubulin folding;0.0274242404737305!GO:0006505;GPI anchor metabolic process;0.0274242404737305!GO:0005586;collagen type III;0.0280516913454655!GO:0004674;protein serine/threonine kinase activity;0.0280516913454655!GO:0006595;polyamine metabolic process;0.0280805703309057!GO:0030659;cytoplasmic vesicle membrane;0.0283257336518721!GO:0005581;collagen;0.0285284198079894!GO:0006984;ER-nuclear signaling pathway;0.0285432731737594!GO:0006818;hydrogen transport;0.0285432731737594!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0286172355560994!GO:0022890;inorganic cation transmembrane transporter activity;0.0287371250399489!GO:0001872;zymosan binding;0.0287934578174384!GO:0001878;response to yeast;0.0287934578174384!GO:0042158;lipoprotein biosynthetic process;0.0288961012107902!GO:0006607;NLS-bearing substrate import into nucleus;0.0291579913452687!GO:0051348;negative regulation of transferase activity;0.0293078376329261!GO:0007030;Golgi organization and biogenesis;0.0293078376329261!GO:0008033;tRNA processing;0.0294477129953427!GO:0030865;cortical cytoskeleton organization and biogenesis;0.030205841599715!GO:0008632;apoptotic program;0.031049799171966!GO:0044452;nucleolar part;0.031299988849657!GO:0005637;nuclear inner membrane;0.0317387912299387!GO:0031902;late endosome membrane;0.0319226925582883!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0320019753996453!GO:0016860;intramolecular oxidoreductase activity;0.0320019753996453!GO:0043065;positive regulation of apoptosis;0.0320904959876522!GO:0006611;protein export from nucleus;0.0323103591615089!GO:0019798;procollagen-proline dioxygenase activity;0.0323898885399591!GO:0003678;DNA helicase activity;0.032613522865733!GO:0016408;C-acyltransferase activity;0.0328358172037047!GO:0046467;membrane lipid biosynthetic process;0.0336028842237896!GO:0051271;negative regulation of cell motility;0.0340897614626996!GO:0006405;RNA export from nucleus;0.034477771909125!GO:0019752;carboxylic acid metabolic process;0.0349075511978566!GO:0006739;NADP metabolic process;0.0352943486536786!GO:0008234;cysteine-type peptidase activity;0.0360256495599641!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0366729504864426!GO:0043068;positive regulation of programmed cell death;0.0368436899835064!GO:0003682;chromatin binding;0.0372415085296929!GO:0008097;5S rRNA binding;0.0373035233806024!GO:0008610;lipid biosynthetic process;0.0373035233806024!GO:0006417;regulation of translation;0.0374829056234111!GO:0006082;organic acid metabolic process;0.0380820047393704!GO:0016126;sterol biosynthetic process;0.0383724857733148!GO:0006355;regulation of transcription, DNA-dependent;0.0384675645344673!GO:0007178;transmembrane receptor protein serine/threonine kinase signaling pathway;0.0386288264821246!GO:0005819;spindle;0.0386474893978847!GO:0007265;Ras protein signal transduction;0.0389751943912472!GO:0005801;cis-Golgi network;0.0393187213557334!GO:0031272;regulation of pseudopodium formation;0.0395847502139836!GO:0031269;pseudopodium formation;0.0395847502139836!GO:0031344;regulation of cell projection organization and biogenesis;0.0395847502139836!GO:0031268;pseudopodium organization and biogenesis;0.0395847502139836!GO:0031346;positive regulation of cell projection organization and biogenesis;0.0395847502139836!GO:0031274;positive regulation of pseudopodium formation;0.0395847502139836!GO:0051101;regulation of DNA binding;0.0405488731853215!GO:0000096;sulfur amino acid metabolic process;0.0405500743651759!GO:0031461;cullin-RING ubiquitin ligase complex;0.0407777184069919!GO:0051052;regulation of DNA metabolic process;0.040999197230528!GO:0005669;transcription factor TFIID complex;0.0410270233672283!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0414421235939986!GO:0005096;GTPase activator activity;0.0415856117245746!GO:0031123;RNA 3'-end processing;0.0416570928108849!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0420850783005277!GO:0006144;purine base metabolic process;0.0422827714486177!GO:0030131;clathrin adaptor complex;0.0422827714486177!GO:0048144;fibroblast proliferation;0.0424998313419063!GO:0048145;regulation of fibroblast proliferation;0.0424998313419063!GO:0017134;fibroblast growth factor binding;0.0426455189488923!GO:0004656;procollagen-proline 4-dioxygenase activity;0.0426455189488923!GO:0031545;peptidyl-proline 4-dioxygenase activity;0.0426455189488923!GO:0051045;negative regulation of membrane protein ectodomain proteolysis;0.0433600596336351!GO:0051043;regulation of membrane protein ectodomain proteolysis;0.0433600596336351!GO:0005874;microtubule;0.0433921338493601!GO:0004287;prolyl oligopeptidase activity;0.0438713247716316!GO:0006007;glucose catabolic process;0.0443574364946586!GO:0003923;GPI-anchor transamidase activity;0.0444119012350524!GO:0016255;attachment of GPI anchor to protein;0.0444119012350524!GO:0042765;GPI-anchor transamidase complex;0.0444119012350524!GO:0007160;cell-matrix adhesion;0.0444526924103324!GO:0016584;nucleosome positioning;0.0446634527140229!GO:0007034;vacuolar transport;0.0446962534174607!GO:0008320;protein transmembrane transporter activity;0.0447268547356589!GO:0006701;progesterone biosynthetic process;0.044736270222007!GO:0030522;intracellular receptor-mediated signaling pathway;0.0449401283737098!GO:0008475;procollagen-lysine 5-dioxygenase activity;0.0453179633292982!GO:0030508;thiol-disulfide exchange intermediate activity;0.0456235651550349!GO:0030145;manganese ion binding;0.0463460857950617!GO:0044433;cytoplasmic vesicle part;0.0466181733423018!GO:0008484;sulfuric ester hydrolase activity;0.04664450176678!GO:0006378;mRNA polyadenylation;0.0467295941843414!GO:0007040;lysosome organization and biogenesis;0.0467295941843414!GO:0031589;cell-substrate adhesion;0.0472695519712509!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0473441957224992!GO:0006635;fatty acid beta-oxidation;0.0473847402260871!GO:0000118;histone deacetylase complex;0.0473847402260871!GO:0032940;secretion by cell;0.0478124587195556!GO:0045936;negative regulation of phosphate metabolic process;0.0479752577040704!GO:0048146;positive regulation of fibroblast proliferation;0.0484028912883472!GO:0006261;DNA-dependent DNA replication;0.0494822655708588 | |||
|sample_id=11555 | |||
|sample_note= | |||
|sample_sex=M | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=skin | |||
|top_motifs=HBP1_HMGB_SSRP1_UBTF:2.23979697424;NKX2-2,8:2.04619402822;ZNF238:2.03848161531;GZF1:2.01960393322;NKX3-1:1.80534133482;HMGA1,2:1.78894932405;TAL1_TCF{3,4,12}:1.56022178647;MYBL2:1.55352029768;HIF1A:1.39201375776;ESR1:1.35692681081;TFAP4:1.33079986281;XBP1:1.32402917541;NKX3-2:1.30214803187;TEAD1:1.30006237637;NR3C1:1.22594586691;NFIX:1.14274231881;KLF4:1.10094062528;FOXD3:1.059977559;HOX{A5,B5}:1.05937085812;FOXL1:1.02792002873;GFI1B:1.02741963886;TEF:1.02231702162;NANOG{mouse}:1.00376983054;ATF6:0.985684879869;HSF1,2:0.978431529808;DBP:0.957787021903;UFEwm:0.936093882882;TP53:0.925758016977;NKX2-3_NKX2-5:0.915955470332;EVI1:0.915621897755;LHX3,4:0.904474041149;MZF1:0.903338777416;SRF:0.901195051383;SOX17:0.883480990183;EN1,2:0.871795709568;HAND1,2:0.86885364377;MAFB:0.868046512639;HOX{A4,D4}:0.805174140992;ALX4:0.793277627023;GTF2I:0.782957697919;TFAP2{A,C}:0.773704996893;MAZ:0.76118273557;ZNF384:0.752514253648;NFATC1..3:0.749836353201;GTF2A1,2:0.732888779696;GCM1,2:0.72443453554;RXR{A,B,G}:0.704787373146;PATZ1:0.698613690997;PRDM1:0.685029706433;NKX6-1,2:0.683426490689;PDX1:0.649933212019;BPTF:0.647032674072;NFE2L1:0.630516213065;HMX1:0.61332927997;SPZ1:0.605456732674;PAX1,9:0.598362579238;STAT5{A,B}:0.588067178105;TLX1..3_NFIC{dimer}:0.584575866201;ADNP_IRX_SIX_ZHX:0.580206801692;GATA4:0.576932335101;HES1:0.519434544261;NR6A1:0.515751346957;PRRX1,2:0.507819854035;GLI1..3:0.503587914361;MTE{core}:0.500578994894;HLF:0.479919833776;T:0.479871901601;FOXO1,3,4:0.473718114419;RXRA_VDR{dimer}:0.470498162865;STAT1,3:0.458662876186;IKZF1:0.424174149144;TFAP2B:0.418846093072;CDC5L:0.40686796035;NR1H4:0.399612525059;TBX4,5:0.396569364836;CRX:0.395920010959;PAX5:0.395222152698;POU5F1:0.378517552133;GFI1:0.377932750277;MYFfamily:0.375310146321;AIRE:0.373221623092;AHR_ARNT_ARNT2:0.348761691241;YY1:0.336380420348;FOX{I1,J2}:0.336309563575;EBF1:0.331998143723;TFCP2:0.330455518184;IRF1,2:0.317400252143;CEBPA,B_DDIT3:0.310446230235;SOX5:0.304557321401;PAX8:0.261440480429;FOXA2:0.261060927838;DMAP1_NCOR{1,2}_SMARC:0.252353062245;XCPE1{core}:0.226215075056;NFE2L2:0.205481525559;HOX{A6,A7,B6,B7}:0.180736173561;HIC1:0.179372521064;EGR1..3:0.179352145574;SMAD1..7,9:0.177045482475;ZNF148:0.163519181323;POU3F1..4:0.157199989495;ELK1,4_GABP{A,B1}:0.151250564908;MTF1:0.137370910075;EP300:0.136612019334;FOX{D1,D2}:0.115677123422;BACH2:0.109719916777;TFDP1:0.107321426691;STAT2,4,6:0.107133782789;NFE2:0.103232323648;RREB1:0.095764945259;RUNX1..3:0.0893081500213;MEF2{A,B,C,D}:0.0860062368058;ZFP161:0.0734367379234;ZIC1..3:0.0681492382393;NRF1:0.047962654754;NHLH1,2:0.0462710115701;ZBTB6:0.0458031630972;VSX1,2:0.0399474317903;ZNF143:0.0318155520713;HNF1A:0.0256405194487;TBP:0.0204803277459;TOPORS:0.0152482025781;MED-1{core}:0.00342155333633;LEF1_TCF7_TCF7L1,2:-0.0230052750459;FOS_FOS{B,L1}_JUN{B,D}:-0.0706373685838;SP1:-0.07660807924;POU1F1:-0.100985419454;RFX1:-0.10242962106;bHLH_family:-0.143664738561;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.152106110929;CDX1,2,4:-0.152662063066;ARID5B:-0.175440809686;REST:-0.190506400624;PAX3,7:-0.215689551558;ZNF423:-0.224187845762;MYB:-0.246342601193;NKX2-1,4:-0.248822714834;FOSL2:-0.250671911065;RBPJ:-0.280529870859;POU6F1:-0.289397181334;SOX2:-0.294364186676;ALX1:-0.312842614226;ATF5_CREB3:-0.34143724727;TGIF1:-0.357052026864;FOXM1:-0.365851338811;PAX4:-0.405414503275;SREBF1,2:-0.409728969438;HNF4A_NR2F1,2:-0.419775249329;E2F1..5:-0.430599398767;ATF4:-0.434047247419;CREB1:-0.441972344257;SPI1:-0.456173842696;NFKB1_REL_RELA:-0.45689427562;ETS1,2:-0.505931981606;JUN:-0.512513063522;ZBTB16:-0.516705156705;FOXN1:-0.533934142671;FOXP3:-0.537510887507;ATF2:-0.547769525438;TLX2:-0.558056586431;ELF1,2,4:-0.570729992981;IRF7:-0.572375899589;FOXP1:-0.578742939001;AR:-0.579355194354;NFIL3:-0.580076987212;SPIB:-0.589477032691;FOXQ1:-0.607209574932;PAX2:-0.613659204447;CUX2:-0.665025418095;PAX6:-0.665467184012;ONECUT1,2:-0.680971025791;RFX2..5_RFXANK_RFXAP:-0.695256920473;PBX1:-0.723176695235;ESRRA:-0.728396726906;GATA6:-0.732477166817;PPARG:-0.736761306173;IKZF2:-0.754716586208;BREu{core}:-0.760604724727;NFY{A,B,C}:-0.829541903058;FOX{F1,F2,J1}:-0.848760349797;OCT4_SOX2{dimer}:-0.848849913558;ZEB1:-0.850213702126;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.883805504519;POU2F1..3:-0.97263359835;RORA:-0.992041679705;PITX1..3:-0.995585912847;SNAI1..3:-1.00380873299;NANOG:-1.02476929313;NR5A1,2:-1.06397021496;SOX{8,9,10}:-1.15528631658;LMO2:-1.23749165898;HOXA9_MEIS1:-1.43309536516;MYOD1:-1.65849037737 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11555-120C7;search_select_hide=table117:FF:11555-120C7 | |||
}} | }} |
Latest revision as of 18:08, 4 June 2020
Name: | Fibroblast - skin spinal muscular atrophy, donor1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11074 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11074
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11074
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.293 |
10 | 10 | 0.629 |
100 | 100 | 0.707 |
101 | 101 | 0.236 |
102 | 102 | 0.00565 |
103 | 103 | 0.776 |
104 | 104 | 0.498 |
105 | 105 | 0.664 |
106 | 106 | 0.2 |
107 | 107 | 0.938 |
108 | 108 | 0.924 |
109 | 109 | 0.158 |
11 | 11 | 0.264 |
110 | 110 | 0.432 |
111 | 111 | 0.0647 |
112 | 112 | 0.7 |
113 | 113 | 0.00194 |
114 | 114 | 0.64 |
115 | 115 | 0.717 |
116 | 116 | 0.424 |
117 | 117 | 0.109 |
118 | 118 | 0.285 |
119 | 119 | 0.227 |
12 | 12 | 0.327 |
120 | 120 | 0.959 |
121 | 121 | 0.518 |
122 | 122 | 0.114 |
123 | 123 | 2.73148e-4 |
124 | 124 | 0.634 |
125 | 125 | 0.873 |
126 | 126 | 0.858 |
127 | 127 | 0.385 |
128 | 128 | 0.471 |
129 | 129 | 0.305 |
13 | 13 | 0.207 |
130 | 130 | 0.132 |
131 | 131 | 0.909 |
132 | 132 | 0.264 |
133 | 133 | 0.546 |
134 | 134 | 0.342 |
135 | 135 | 0.29 |
136 | 136 | 0.0152 |
137 | 137 | 0.442 |
138 | 138 | 0.521 |
139 | 139 | 0.393 |
14 | 14 | 0.357 |
140 | 140 | 0.431 |
141 | 141 | 0.104 |
142 | 142 | 0.661 |
143 | 143 | 0.453 |
144 | 144 | 0.185 |
145 | 145 | 0.572 |
146 | 146 | 0.936 |
147 | 147 | 0.161 |
148 | 148 | 0.0614 |
149 | 149 | 0.0333 |
15 | 15 | 0.15 |
150 | 150 | 0.721 |
151 | 151 | 0.493 |
152 | 152 | 0.479 |
153 | 153 | 0.0549 |
154 | 154 | 0.927 |
155 | 155 | 0.0197 |
156 | 156 | 0.79 |
157 | 157 | 0.308 |
158 | 158 | 3.81296e-4 |
159 | 159 | 0.299 |
16 | 16 | 0.31 |
160 | 160 | 0.841 |
161 | 161 | 0.167 |
162 | 162 | 0.781 |
163 | 163 | 0.452 |
164 | 164 | 0.888 |
165 | 165 | 0.522 |
166 | 166 | 0.0142 |
167 | 167 | 0.217 |
168 | 168 | 0.837 |
169 | 169 | 0.443 |
17 | 17 | 0.555 |
18 | 18 | 0.29 |
19 | 19 | 0.0555 |
2 | 2 | 0.756 |
20 | 20 | 0.436 |
21 | 21 | 0.0326 |
22 | 22 | 0.465 |
23 | 23 | 0.639 |
24 | 24 | 0.277 |
25 | 25 | 0.231 |
26 | 26 | 0.804 |
27 | 27 | 0.981 |
28 | 28 | 0.256 |
29 | 29 | 0.634 |
3 | 3 | 0.941 |
30 | 30 | 0.242 |
31 | 31 | 0.851 |
32 | 32 | 9.20699e-10 |
33 | 33 | 0.469 |
34 | 34 | 0.904 |
35 | 35 | 0.755 |
36 | 36 | 0.0645 |
37 | 37 | 0.433 |
38 | 38 | 0.286 |
39 | 39 | 0.367 |
4 | 4 | 0.286 |
40 | 40 | 0.0292 |
41 | 41 | 0.966 |
42 | 42 | 0.478 |
43 | 43 | 0.573 |
44 | 44 | 0.437 |
45 | 45 | 0.613 |
46 | 46 | 0.616 |
47 | 47 | 0.241 |
48 | 48 | 0.31 |
49 | 49 | 0.235 |
5 | 5 | 0.693 |
50 | 50 | 0.881 |
51 | 51 | 0.688 |
52 | 52 | 0.879 |
53 | 53 | 0.163 |
54 | 54 | 0.988 |
55 | 55 | 0.0999 |
56 | 56 | 0.783 |
57 | 57 | 0.942 |
58 | 58 | 0.115 |
59 | 59 | 0.772 |
6 | 6 | 0.891 |
60 | 60 | 0.175 |
61 | 61 | 0.416 |
62 | 62 | 0.306 |
63 | 63 | 0.629 |
64 | 64 | 0.309 |
65 | 65 | 0.881 |
66 | 66 | 0.299 |
67 | 67 | 0.459 |
68 | 68 | 0.924 |
69 | 69 | 0.693 |
7 | 7 | 0.0879 |
70 | 70 | 0.887 |
71 | 71 | 0.69 |
72 | 72 | 0.788 |
73 | 73 | 0.624 |
74 | 74 | 0.165 |
75 | 75 | 0.21 |
76 | 76 | 0.797 |
77 | 77 | 0.432 |
78 | 78 | 0.06 |
79 | 79 | 0.13 |
8 | 8 | 0.63 |
80 | 80 | 0.621 |
81 | 81 | 0.646 |
82 | 82 | 0.801 |
83 | 83 | 0.258 |
84 | 84 | 0.423 |
85 | 85 | 0.659 |
86 | 86 | 0.736 |
87 | 87 | 0.709 |
88 | 88 | 0.38 |
89 | 89 | 0.63 |
9 | 9 | 0.843 |
90 | 90 | 0.889 |
91 | 91 | 0.799 |
92 | 92 | 0.635 |
93 | 93 | 0.782 |
94 | 94 | 0.692 |
95 | 95 | 0.901 |
96 | 96 | 0.914 |
97 | 97 | 0.517 |
98 | 98 | 0.0581 |
99 | 99 | 0.00849 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11074
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000251 human fibroblast - skin spinal muscular atrophy sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0002320 (connective tissue cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
0000057 (fibroblast)
0002620 (skin fibroblast)
UBERON: Anatomy
0000468 (multi-cellular organism)
0002097 (skin of body)
0002199 (integument)
0002384 (connective tissue)
0000479 (tissue)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0003102 (surface structure)
0002416 (integumental system)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000057 (fibroblast sample)
0000250 (human fibroblast of skin sample)
0000001 (sample)
0000251 (human fibroblast - skin spinal muscular atrophy sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)