FF:11917-125G9: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005705 | ||
| | |accession_numbers=CAGE;DRX008189;DRR009061;DRZ000486;DRZ001871;DRZ011836;DRZ013221 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003 | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001 | ||
|comment=Changed from previous label. TODO: full classification | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr7:50343634..50343717,+!p2@IKZF1!1.82!65.22!IKZF1;;chr10:8096772..8096787,+!p2@GATA3!1.65!51.12!GATA3;;chr2:192015701..192015743,-!p1@STAT4!1.62!54.99!STAT4;;chr10:8096631..8096660,+!p1@GATA3!1.61!48.08!GATA3;;chr3:18486354..18486377,-!p2@SATB1!1.56!43.94!SATB1;;chr7:50344289..50344323,+!p1@IKZF1!1.55!34.54!IKZF1;;chr17:1959369..1959388,+!p2@HIC1!1.52!82.91!HIC1;;chr20:50159198..50159299,-!p1@NFATC2!1.51!45.60!NFATC2;;chr2:231090433..231090469,+!p1@SP140!1.45!27.36!SP140;;chr6:391743..391759,+!p1@IRF4!1.44!26.81!IRF4;;chr2:192015750..192015793,-!p2@STAT4!1.43!34.82!STAT4;;chr1:25291475..25291511,-!p2@RUNX3!1.43!25.70!RUNX3;;chr7:50344251..50344288,+!p3@IKZF1!1.42!25.42!IKZF1;;chr9:117150254..117150271,-!p1@AKNA!1.40!64.11!AKNA;;chr8:60031619..60031676,-!p1@TOX!1.40!51.40!TOX;;chr1:92951607..92951661,-!p1@GFI1!1.40!24.32!GFI1;;chr5:133450365..133450444,+!p1@TCF7!1.37!98.66!TCF7;;chr7:50343895..50343936,+!p5@IKZF1!1.34!20.73!IKZF1;;chr14:75988771..75988826,+!p1@BATF!1.33!26.81!BATF;;chr16:68119324..68119364,+!p1@NFATC3!1.32!86.50!NFATC3;;chrY:21906594..21906622,-!p1@KDM5D!1.31!19.34!KDM5D;;chr7:50348268..50348366,+!p4@IKZF1!1.29!18.52!IKZF1;;chr20:56195474..56195506,-!p1@ZBP1!1.28!17.96!ZBP1;;chr3:63953435..63953499,+!p1@ATXN7!1.22!15.75!ATXN7;;chr6:91006518..91006570,-!p1@BACH2!1.21!34.54!BACH2;;chr14:99738138..99738163,-!p1@BCL11B!1.19!14.37!BCL11B;;chr10:8095593..8095625,+!p3@GATA3!1.18!16.58!GATA3;;chr4:109087445..109087463,-!p1@LEF1!1.17!13.82!LEF1;;chr4:109089901..109089930,-!p3@LEF1!1.17!13.82!LEF1;;chr3:71355163..71355209,-!p5@FOXP1!1.16!18.79!FOXP1;;chr5:133451294..133451310,+!p2@TCF7!1.16!13.54!TCF7;;chr19:19729477..19729542,-!p1@PBX4!1.14!27.36!PBX4;;chr20:56195525..56195556,-!p2@ZBP1!1.10!11.61!ZBP1;;chr13:41593425..41593480,-!p1@ELF1!1.06!67.71!ELF1;;chr2:231090471..231090504,+!p2@SP140!0.99!8.84!SP140;;chr7:77428066..77428132,+!p2@PHTF2!0.97!55.27!PHTF2;;chr6:15401104..15401166,+!p5@JARID2!0.97!8.29!JARID2;;chr17:45810594..45810608,+!p1@TBX21!0.95!8.01!TBX21;;chr5:176738887..176738934,-!p1@MXD3!0.94!53.34!MXD3;;chr2:97202991..97203043,+!p3@ARID5A!0.94!7.74!ARID5A;;chr4:109090075..109090095,-!p2@LEF1!0.94!7.74!LEF1;;chr19:16435625..16435682,+!p1@KLF2!0.93!251.20!KLF2;;chr20:52226313..52226350,-!p3@ZNF217!0.93!7.46!ZNF217;;chr2:8822176..8822196,+!p1@ID2!0.92!1067.26!ID2;;chr3:18466787..18466839,-!p1@SATB1!0.92!33.71!SATB1;;chr1:25256756..25256774,-!p1@RUNX3!0.91!13.82!RUNX3;;chr17:46621146..46621180,-!p10@HOXB2!0.91!7.19!HOXB2;;chr3:71007344..71007348,-!p6@FOXP1!0.90!29.29!FOXP1;;chr21:36421535..36421610,-!p2@RUNX1!0.90!25.98!RUNX1;;chr2:214015343..214015366,-!p3@IKZF2!0.90!6.91!IKZF2;;chr3:18480217..18480239,-!p3@SATB1!0.90!6.91!SATB1;;chr11:47236584..47236679,+!p1@DDB2!0.89!77.10!DDB2;;chr5:131826457..131826514,-!p1@IRF1!0.88!274.14!IRF1;;chr16:79634595..79634620,-!p2@MAF!0.88!12.44!MAF;;chr12:56415246..56415286,+!p2@IKZF4!0.88!6.63!IKZF4;;chr1:92949331..92949377,-!p2@GFI1!0.87!6.36!GFI1;;chr4:109088089..109088101,-!p11@LEF1!0.87!6.36!LEF1;;chr11:128392085..128392232,-!p1@ETS1!0.85!218.87!ETS1;;chr10:35484053..35484076,+!p1@CREM!0.85!16.03!CREM;;chr1:23857698..23857733,-!p1@E2F2!0.85!11.61!E2F2;;chr3:71542684..71542720,-!p18@FOXP1!0.85!6.08!FOXP1;;chr7:137620650..137620677,-!p3@CREB3L2!0.85!6.08!CREB3L2;;chr8:60031563..60031574,-!p7@TOX!0.85!6.08!TOX;;chr14:99738059..99738086,-!p2@BCL11B!0.85!6.08!BCL11B;;chrX:49121165..49121179,-!p1@FOXP3!0.85!6.08!FOXP3;;chrX:134477924..134477988,-!p1@ZNF75D!0.84!23.77!ZNF75D;;chr6:45390269..45390298,+!p5@RUNX2!0.84!10.22!RUNX2;;chr11:128563948..128564003,+!p1@FLI1!0.83!73.79!FLI1;;chr16:79634624..79634642,-!p1@MAF!0.83!24.04!MAF;;chr6:106546808..106546833,+!p3@PRDM1!0.83!7.46!PRDM1;;chrY:2803415..2803468,+!p1@ZFY!0.83!5.80!ZFY;;chr5:321810..321877,+!p1@AHRR!0.82!18.79!AHRR;;chr16:89787937..89787971,+!p1@ZNF276!0.82!15.48!ZNF276;;chr17:46621101..46621143,-!p7@HOXB2!0.82!7.74!HOXB2;;chr16:88752889..88752921,-!p1@SNAI3!0.82!6.63!SNAI3;;chr11:113930425..113930471,+!p1@ZBTB16!0.81!8.01!ZBTB16;;chr3:18487057..18487105,-!p4@SATB1!0.80!5.25!SATB1;;chr4:109088940..109089037,-!p4@LEF1!0.80!5.25!LEF1;;chr17:38020392..38020477,-!p1@IKZF3!0.80!5.25!IKZF3;;chr7:137620684..137620711,-!p4@CREB3L2!0.80!5.25!CREB3L2;;chr6:15249128..15249177,+!p4@JARID2!0.79!9.67!JARID2;;chr7:128577972..128578047,+!p1@IRF5!0.79!8.57!IRF5;;chr7:50343864..50343888,+!p7@IKZF1!0.78!4.97!IKZF1;;chr21:36421147..36421193,-!p10@RUNX1!0.78!4.97!RUNX1;;chr17:56565257..56565283,-!p2@HSF5!0.78!4.97!HSF5;;chr3:71179699..71179744,-!p2@FOXP1!0.76!38.97!FOXP1;;chr14:64970670..64970712,-!p3@ZBTB25!0.76!11.05!ZBTB25;;chr4:109089996..109090012,-!p5@LEF1!0.76!4.70!LEF1;;chr14:99737850..99737852,-!p3@BCL11B!0.76!4.70!BCL11B;;chr15:60884706..60884743,-!p1@RORA!0.74!25.70!RORA;;chr2:214015111..214015179,-!p1@IKZF2!0.74!8.57!IKZF2;;chr17:40440481..40440550,+!p1@STAT5A!0.73!34.82!STAT5A;;chr14:64971288..64971316,-!p2@ZBTB25!0.73!14.92!ZBTB25;;chr2:148778973..148779035,+!p3@MBD5!0.73!12.44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2.49!ZNF644;;chr1:211433151..211433191,+!p5@RCOR3!0.20!2.21!RCOR3;;chr19:45004584..45004601,-!p2@ZNF180!0.20!1.93!ZNF180;;chr1:249153114..249153175,-!p3@ZNF692!0.20!1.93!ZNF692;;chr9:128509635..128509658,+!p2@PBX3!0.20!1.93!PBX3;;chr8:123793959..123793977,+!p4@ZHX2!0.20!1.93!ZHX2;;chr3:150126440..150126455,+!p9@TSC22D2!0.20!1.38!TSC22D2;;chr3:71632743..71632756,-!p16@FOXP1!0.20!1.38!FOXP1;;chr16:30569604..30569629,-!p3@ZNF764!0.20!1.38!ZNF764;;chr6:15249097..15249115,+!p7@JARID2!0.20!1.11!JARID2;;chr6:157099387..157099403,+!p8@ARID1B!0.20!1.11!ARID1B;;chr7:27835758..27835772,+!p3@TAX1BP1!0.20!1.11!TAX1BP1;;chrX:129402754..129402766,-!p3@ZNF280C!0.20!1.11!ZNF280C;;chr17:38497662..38497713,+!p4@RARA!0.20!0.83!RARA;;chr19:19779686..19779697,+!p3@ZNF101!0.20!0.83!ZNF101;;chr19:24269971..24269980,+!p6@ZNF254!0.20!0.83!ZNF254;;chr10:35416125..35416138,+!p10@CREM!0.20!0.83!CREM;;chr7:127032296..127032317,-!p4@ZNF800!0.20!0.83!ZNF800;;chr2:70314601..70314622,+!p1@PCBP1!0.19!325.54!PCBP1;;chr3:52008016..52008071,-!p1@ABHD14A-ACY1,p1@ABHD14B,p1@PCBP4!0.19!80.14!PCBP4;;chr17:7590797..7590815,-!p1@TP53!0.19!60.24!TP53;;chr19:10305581..10305646,-!p1@DNMT1!0.19!48.36!DNMT1;;chr17:56065540..56065627,-!p1@VEZF1!0.19!43.11!VEZF1;;chr8:41909496..41909512,-!p1@KAT6A!0.19!41.73!KAT6A;;chr1:22778337..22778356,+!p1@ZBTB40!0.19!16.30!ZBTB40;;chr20:62601243..62601291,-!p1@ZNF512B!0.19!13.26!ZNF512B;;chr12:51566849..51566927,-!p1@TFCP2!0.19!11.33!TFCP2;;chr1:8877692..8877732,-!p1@RERE!0.19!10.78!RERE;;chr16:58034520..58034622,-!p@chr16:58034520..58034622,-!0.19!10.22!ZNF319;;chr17:33288552..33288598,+!p1@ZNF830!0.19!10.22!ZNF830;;chr9:99540335..99540388,-!p1@ZNF510!0.19!9.67!ZNF510;;chr7:148936732..148936761,+!p1@ZNF212!0.19!9.12!ZNF212;;chr9:125667518..125667588,-!p1@RC3H2!0.19!8.57!RC3H2;;chr8:135725249..135725292,-!p1@ZFAT!0.19!8.29!ZFAT;;chr19:57831829..57831890,+!p1@ZNF543!0.19!8.01!ZNF543;;chr4:2263861..2263883,-!p2@MXD4!0.19!7.74!MXD4;;chr2:178257401..178257432,-!p4@NFE2L2!0.19!7.19!NFE2L2;;chr16:3285144..3285191,-!p1@ZNF200!0.19!6.08!ZNF200;;chr3:71179746..71179783,-!p7@FOXP1!0.19!3.87!FOXP1;;chr1:8585945..8586056,-!p3@RERE!0.19!3.87!RERE;;chr8:28748099..28748141,+!p2@HMBOX1!0.19!3.59!HMBOX1;;chr6:109804367..109804402,-!p2@ZBTB24!0.19!3.32!ZBTB24;;chr1:27022839..27022890,+!p3@ARID1A!0.19!3.32!ARID1A;;chr1:78444714..78444725,-!p3@FUBP1!0.19!3.04!FUBP1;;chr19:12721790..12721810,+!p2@ZNF791!0.19!3.04!ZNF791;;chr19:37862054..37862110,+!p1@ZNF527!0.19!3.04!ZNF527;;chr16:3185125..3185173,+!p1@ZNF213!0.19!2.76!ZNF213;;chr2:174830043..174830071,-!p6@SP3!0.19!2.21!SP3;;chr19:57752200..57752254,+!p3@ZNF805!0.19!1.93!ZNF805;;chr6:42419043..42419087,-!p2@TRERF1!0.19!1.93!TRERF1;;chr3:178789648..178789661,-!p4@ZMAT3!0.19!1.38!ZMAT3;;chr20:42143136..42143161,+!p3@L3MBTL1!0.19!1.38!L3MBTL;;chr12:8185346..8185360,+!p2@FOXJ2!0.19!1.38!FOXJ2;;chr7:21467746..21467758,+!p4@SP4!0.19!1.11!SP4;;chr9:99180662..99180690,-!p2@ZNF367!0.19!1.11!ZNF367;;chr19:18391652..18391669,-!p8@JUND!0.19!1.11!JUND;;chr1:158979680..158979683,+!p9@IFI16!0.19!1.11!IFI16;;chr1:45805735..45805743,+!p7@TOE1!0.19!0.83!TOE1;;chr11:130184623..130184634,-!p6@ZBTB44!0.19!0.83!ZBTB44;;chr13:41556186..41556208,-!p12@ELF1!0.19!0.83!ELF1;;chr10:104154415..104154434,+!p5@NFKB2!0.19!0.55!NFKB2;;chr10:135121763..135121783,+!p5@ZNF511!0.19!0.55!ZNF511;;chr10:35416172..35416184,+!p13@CREM!0.19!0.55!CREM;;chr11:128391908..128391913,-!p18@ETS1!0.19!0.55!ETS1;;chr11:128392258..128392264,-!p7@ETS1!0.19!0.55!ETS1;;chr12:103352277..103352324,+!p2@ASCL1!0.19!0.55!ASCL1;;chr12:48277143..48277154,-!p10@VDR!0.19!0.55!VDR;;chr12:69753583..69753598,+!p2@YEATS4!0.19!0.55!YEATS4;;chr12:72056897..72056908,+!p12@THAP2!0.19!0.55!THAP2;;chr12:95467222..95467233,-!p3@NR2C1!0.19!0.55!NR2C1;;chr13:41593392..41593403,-!p7@ELF1!0.19!0.55!ELF1;; | |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000084;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000542;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000624;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000789;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000893;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD4%252bCD25-CD45RA%252b%2520naive%2520conventional%2520T%2520cells%2520expanded%252c%2520donor3.CNhs13814.11917-125G9.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD4%252bCD25-CD45RA%252b%2520naive%2520conventional%2520T%2520cells%2520expanded%252c%2520donor3.CNhs13814.11917-125G9.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD4%252bCD25-CD45RA%252b%2520naive%2520conventional%2520T%2520cells%2520expanded%252c%2520donor3.CNhs13814.11917-125G9.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD4%252bCD25-CD45RA%252b%2520naive%2520conventional%2520T%2520cells%2520expanded%252c%2520donor3.CNhs13814.11917-125G9.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD4%252bCD25-CD45RA%252b%2520naive%2520conventional%2520T%2520cells%2520expanded%252c%2520donor3.CNhs13814.11917-125G9.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11917-125G9 | |||
|is_a=EFO:0002091;;FF:0000002;;FF:0000210 | |is_a=EFO:0002091;;FF:0000002;;FF:0000210 | ||
|is_obsolete= | |||
|library_id=CNhs13814 | |||
|library_id_phase_based=2:CNhs13814 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11917 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11917 | |||
|name=CD4+CD25-CD45RA+ naive conventional T cells expanded, donor3 | |||
|namespace= | |namespace= | ||
|part_of= | |part_of= | ||
|profile_cagescan= | |||
|profile_hcage=CNhs13814,LSID1092,release014,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq= | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.030769532867666,0.542470648920814,0.23177997534443,0.868652491367374,0,0,0,0,0,0,0,0,0,0,0.262225590440628,0.575591940894526,0,0.22357317975679,0,0,0,0,0,0.678329153955799,0,0,0.749704557374979,0,0,0,0,0,0,0,0,0,0,0,0,0.16192973095118,0.50661327355052,0,0,0,0,0,0,0,0.229091615662426,0,0,0,0,0,0,0,0.637135134184983,0,0,0.537757954666916,0,0,0,0,0,0,0,0,0.191087562954052,0,0.191087562954052,0,0,0.105969788764328,0,0,0,0,0,0,0,0.0296124282282102,0,-0.0093922743062369,-0.117376992543557,0,0,0,-0.217812482172458,0.137653015556417,0,0,0.131112795220314,0,0.164190239202922,0.824031939809079,0,0,0,0,0,0,0.105969788764328,0,0,0,0,0,0,0,0,0,0,-0.096373593922461,0.323334633274257,0,0,0.13616736863467,0.237257282454537,0,0.105969788764328,0.376896190105218,0,0,0 | |||
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| |||
|rna_box=125 | |||
|rna_catalog_number= | |||
|rna_concentration=0.51888 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=61-62 | |||
|rna_od260/230=1.35 | |||
|rna_od260/280=2.03 | |||
|rna_position=G9 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=125G9 | |||
|rna_weight_ug=5.1888 | |||
|sample_age=23 | |||
|sample_category=primary cells | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=T cell | |||
|sample_collaboration=Michael Rehli (University of Regensberg) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.84315137889694e-232!GO:0043227;membrane-bound organelle;8.22929445728282e-204!GO:0043231;intracellular membrane-bound organelle;1.8702359734326e-203!GO:0043226;organelle;2.73759618045461e-191!GO:0043229;intracellular organelle;1.41362248871836e-190!GO:0005737;cytoplasm;3.08723774894779e-152!GO:0044422;organelle part;3.20044237681282e-136!GO:0044446;intracellular organelle part;2.27002100681459e-134!GO:0044444;cytoplasmic part;3.35686092236969e-109!GO:0032991;macromolecular complex;9.79714457196181e-105!GO:0044237;cellular metabolic process;1.84450202624053e-99!GO:0005634;nucleus;2.21661438315862e-97!GO:0043170;macromolecule metabolic process;4.50869307081378e-95!GO:0044238;primary metabolic process;2.00506078026458e-94!GO:0030529;ribonucleoprotein complex;1.53280731955224e-88!GO:0044428;nuclear part;3.24804714140179e-75!GO:0003723;RNA binding;4.25765346999494e-72!GO:0005739;mitochondrion;1.92760044892131e-68!GO:0043233;organelle lumen;3.03837912814961e-67!GO:0031974;membrane-enclosed lumen;3.03837912814961e-67!GO:0043283;biopolymer metabolic process;1.19110736471418e-60!GO:0005515;protein binding;4.99226198822051e-56!GO:0006412;translation;1.0019362210355e-53!GO:0043234;protein complex;1.62539142877645e-53!GO:0005840;ribosome;6.9068054865632e-53!GO:0019538;protein metabolic process;1.32450515673646e-51!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;6.98728475274099e-51!GO:0006396;RNA processing;9.09863283411165e-50!GO:0044267;cellular protein metabolic process;3.59771400772782e-48!GO:0010467;gene expression;6.58440343064555e-48!GO:0033036;macromolecule localization;1.81938035403496e-47!GO:0044260;cellular macromolecule metabolic process;1.93752157041271e-47!GO:0044429;mitochondrial part;3.38933949886636e-47!GO:0003735;structural constituent of ribosome;9.72863940576462e-47!GO:0015031;protein transport;1.82652077377337e-45!GO:0008104;protein localization;4.90115872099051e-44!GO:0045184;establishment of protein localization;1.36157070085523e-43!GO:0031090;organelle membrane;1.4472839071583e-43!GO:0016071;mRNA metabolic process;1.48110479368694e-43!GO:0031967;organelle envelope;4.9816408588287e-43!GO:0031975;envelope;1.1729433886073e-42!GO:0031981;nuclear lumen;3.1933210533764e-42!GO:0006259;DNA metabolic process;1.91882394098052e-41!GO:0009059;macromolecule biosynthetic process;2.82855108511855e-41!GO:0033279;ribosomal subunit;4.64776006717479e-40!GO:0006397;mRNA processing;2.0708379469111e-37!GO:0008380;RNA splicing;4.9351823183614e-37!GO:0005829;cytosol;3.26624416156043e-36!GO:0044249;cellular biosynthetic process;3.39689935127693e-36!GO:0009058;biosynthetic process;7.32682865467236e-36!GO:0046907;intracellular transport;9.07298746427434e-35!GO:0016043;cellular component organization and biogenesis;1.97055418435628e-34!GO:0003676;nucleic acid binding;1.00019091089149e-33!GO:0006886;intracellular protein transport;4.24472728998842e-33!GO:0065003;macromolecular complex assembly;6.40547874279553e-33!GO:0005740;mitochondrial envelope;7.5854915742153e-30!GO:0007049;cell cycle;1.90742272372031e-29!GO:0019866;organelle inner membrane;2.35414704416388e-29!GO:0006996;organelle organization and biogenesis;3.44312508938639e-29!GO:0005830;cytosolic ribosome (sensu Eukaryota);7.34802679404079e-29!GO:0022607;cellular component assembly;8.68587880258693e-29!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.65037289071261e-28!GO:0043228;non-membrane-bound organelle;1.6698833723834e-28!GO:0043232;intracellular non-membrane-bound organelle;1.6698833723834e-28!GO:0031966;mitochondrial membrane;2.24348671704998e-28!GO:0005681;spliceosome;2.48143563844697e-28!GO:0000166;nucleotide binding;7.29397724467113e-28!GO:0005654;nucleoplasm;3.20445306870637e-27!GO:0005743;mitochondrial inner membrane;1.99124384166499e-26!GO:0051641;cellular localization;3.73251221259199e-26!GO:0051649;establishment of cellular localization;7.39200404179078e-26!GO:0044445;cytosolic part;2.07999904596541e-25!GO:0006974;response to DNA damage stimulus;8.98504558513987e-25!GO:0005694;chromosome;1.05995417756178e-24!GO:0012501;programmed cell death;1.99395399475948e-24!GO:0006915;apoptosis;2.17673122731671e-24!GO:0022402;cell cycle process;1.25096441437966e-23!GO:0008219;cell death;2.96707580066362e-23!GO:0016265;death;2.96707580066362e-23!GO:0044427;chromosomal part;3.33758827962075e-23!GO:0006512;ubiquitin cycle;1.05208597767414e-22!GO:0006119;oxidative phosphorylation;1.67498274758146e-22!GO:0016070;RNA metabolic process;4.22894273049036e-22!GO:0031980;mitochondrial lumen;3.26160219041881e-21!GO:0005759;mitochondrial matrix;3.26160219041881e-21!GO:0032553;ribonucleotide binding;3.6154071772035e-21!GO:0032555;purine ribonucleotide binding;3.6154071772035e-21!GO:0015935;small ribosomal subunit;5.71159984692946e-21!GO:0044455;mitochondrial membrane part;6.92333965082161e-21!GO:0017076;purine nucleotide binding;1.34899774890705e-20!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.60235186260393e-20!GO:0016462;pyrophosphatase activity;1.96960837718493e-20!GO:0016817;hydrolase activity, acting on acid anhydrides;2.12850434007943e-20!GO:0006281;DNA repair;2.41534366219559e-20!GO:0015934;large ribosomal subunit;2.72542420025411e-20!GO:0051276;chromosome organization and biogenesis;4.62571192922675e-20!GO:0044451;nucleoplasm part;5.36961953099347e-20!GO:0017111;nucleoside-triphosphatase activity;9.94370458355908e-20!GO:0000278;mitotic cell cycle;1.63031426098136e-19!GO:0005524;ATP binding;4.34482298244186e-19!GO:0016874;ligase activity;4.49429124623031e-19!GO:0044265;cellular macromolecule catabolic process;6.32851594726258e-19!GO:0022618;protein-RNA complex assembly;8.65344462613568e-19!GO:0043412;biopolymer modification;9.18308311877262e-19!GO:0032559;adenyl ribonucleotide binding;2.37907349972464e-18!GO:0030554;adenyl nucleotide binding;1.36059800202425e-17!GO:0042981;regulation of apoptosis;2.10128837801811e-17!GO:0005746;mitochondrial respiratory chain;2.68208645975375e-17!GO:0043067;regulation of programmed cell death;4.07280374409161e-17!GO:0006605;protein targeting;6.77927943317362e-17!GO:0006325;establishment and/or maintenance of chromatin architecture;8.37108000271349e-17!GO:0006464;protein modification process;1.04277675253498e-16!GO:0012505;endomembrane system;1.51254388815628e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.94372228518753e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;2.59769231984008e-16!GO:0006323;DNA packaging;2.98006658743586e-16!GO:0019941;modification-dependent protein catabolic process;2.98006658743586e-16!GO:0043632;modification-dependent macromolecule catabolic process;2.98006658743586e-16!GO:0050136;NADH dehydrogenase (quinone) activity;3.3365771627155e-16!GO:0003954;NADH dehydrogenase activity;3.3365771627155e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.3365771627155e-16!GO:0042623;ATPase activity, coupled;3.68788970919392e-16!GO:0022403;cell cycle phase;3.81846624281864e-16!GO:0016887;ATPase activity;5.95812045296952e-16!GO:0044257;cellular protein catabolic process;6.43190355180331e-16!GO:0006511;ubiquitin-dependent protein catabolic process;6.51704502074316e-16!GO:0006913;nucleocytoplasmic transport;6.7590729863501e-16!GO:0043285;biopolymer catabolic process;9.02838092557303e-16!GO:0005730;nucleolus;9.66855261960369e-16!GO:0000502;proteasome complex (sensu Eukaryota);1.12528499180361e-15!GO:0008135;translation factor activity, nucleic acid binding;1.2967484656115e-15!GO:0043687;post-translational protein modification;1.48934880392186e-15!GO:0009719;response to endogenous stimulus;1.50735412684662e-15!GO:0000785;chromatin;1.56338791320121e-15!GO:0051169;nuclear transport;1.61966506409593e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.95185799209403e-15!GO:0051726;regulation of cell cycle;2.07849940841452e-15!GO:0000087;M phase of mitotic cell cycle;2.75100747417502e-15!GO:0000074;regulation of progression through cell cycle;3.6952634348825e-15!GO:0005761;mitochondrial ribosome;3.82744351087639e-15!GO:0000313;organellar ribosome;3.82744351087639e-15!GO:0006457;protein folding;5.60971227221866e-15!GO:0007067;mitosis;5.69772992725953e-15!GO:0009057;macromolecule catabolic process;6.23386782055064e-15!GO:0016604;nuclear body;2.04162927643785e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.20017861025064e-14!GO:0006333;chromatin assembly or disassembly;2.23127857243926e-14!GO:0042775;organelle ATP synthesis coupled electron transport;3.80991704546542e-14!GO:0042773;ATP synthesis coupled electron transport;3.80991704546542e-14!GO:0005635;nuclear envelope;4.25850665668745e-14!GO:0030964;NADH dehydrogenase complex (quinone);4.36290964098709e-14!GO:0045271;respiratory chain complex I;4.36290964098709e-14!GO:0005747;mitochondrial respiratory chain complex I;4.36290964098709e-14!GO:0044248;cellular catabolic process;9.87375134290711e-14!GO:0065004;protein-DNA complex assembly;1.22841379132006e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.58170789234984e-13!GO:0008134;transcription factor binding;2.24024533939898e-13!GO:0048770;pigment granule;2.38720372201464e-13!GO:0042470;melanosome;2.38720372201464e-13!GO:0000398;nuclear mRNA splicing, via spliceosome;2.55302805139615e-13!GO:0000375;RNA splicing, via transesterification reactions;2.55302805139615e-13!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.55302805139615e-13!GO:0031965;nuclear membrane;3.84943618883338e-13!GO:0051186;cofactor metabolic process;3.97189662457564e-13!GO:0006260;DNA replication;8.80306293140795e-13!GO:0003743;translation initiation factor activity;9.81514217184597e-13!GO:0000279;M phase;1.05402468170556e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.72081086437856e-12!GO:0051301;cell division;1.75197695355025e-12!GO:0006413;translational initiation;2.39931085536843e-12!GO:0006334;nucleosome assembly;4.20758170718391e-12!GO:0044453;nuclear membrane part;4.36186512510732e-12!GO:0030163;protein catabolic process;6.82785011784659e-12!GO:0050794;regulation of cellular process;8.17739798795559e-12!GO:0006793;phosphorus metabolic process;1.05329916771966e-11!GO:0006796;phosphate metabolic process;1.05329916771966e-11!GO:0017038;protein import;1.62263549777606e-11!GO:0051082;unfolded protein binding;1.78509592075883e-11!GO:0031497;chromatin assembly;2.92448815338956e-11!GO:0004386;helicase activity;3.0029750629125e-11!GO:0048193;Golgi vesicle transport;5.40949336838233e-11!GO:0016607;nuclear speck;6.78836588921434e-11!GO:0006446;regulation of translational initiation;9.66597178226702e-11!GO:0042254;ribosome biogenesis and assembly;9.89627679662208e-11!GO:0008639;small protein conjugating enzyme activity;1.39897318955273e-10!GO:0006732;coenzyme metabolic process;2.36722547631193e-10!GO:0044432;endoplasmic reticulum part;3.05183169834549e-10!GO:0004842;ubiquitin-protein ligase activity;3.23724688630688e-10!GO:0009259;ribonucleotide metabolic process;3.75278808061018e-10!GO:0019787;small conjugating protein ligase activity;4.77211992348705e-10!GO:0016310;phosphorylation;6.4451912227497e-10!GO:0043566;structure-specific DNA binding;7.27015193900726e-10!GO:0003697;single-stranded DNA binding;7.74440362101767e-10!GO:0007249;I-kappaB kinase/NF-kappaB cascade;7.99163638027594e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;9.4639550961994e-10!GO:0005643;nuclear pore;9.71208044668853e-10!GO:0008026;ATP-dependent helicase activity;1.01939949362538e-09!GO:0006164;purine nucleotide biosynthetic process;1.08306830253526e-09!GO:0009260;ribonucleotide biosynthetic process;1.23838803035954e-09!GO:0016787;hydrolase activity;1.32378156780182e-09!GO:0006163;purine nucleotide metabolic process;1.32378156780182e-09!GO:0006916;anti-apoptosis;1.3505440212547e-09!GO:0005783;endoplasmic reticulum;1.39003066885581e-09!GO:0019829;cation-transporting ATPase activity;1.70797108898377e-09!GO:0005794;Golgi apparatus;1.72666407017646e-09!GO:0043069;negative regulation of programmed cell death;2.6431959972887e-09!GO:0016568;chromatin modification;2.72483103312973e-09!GO:0009152;purine ribonucleotide biosynthetic process;2.74539686884394e-09!GO:0009150;purine ribonucleotide metabolic process;3.5946157525665e-09!GO:0043066;negative regulation of apoptosis;3.67339220421438e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;4.26295473245352e-09!GO:0065002;intracellular protein transport across a membrane;4.3155522280109e-09!GO:0000786;nucleosome;4.50572540582445e-09!GO:0008565;protein transporter activity;5.96034312969924e-09!GO:0050657;nucleic acid transport;6.53085531156513e-09!GO:0051236;establishment of RNA localization;6.53085531156513e-09!GO:0050658;RNA transport;6.53085531156513e-09!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;6.84770983122209e-09!GO:0006403;RNA localization;6.97745514007367e-09!GO:0005839;proteasome core complex (sensu Eukaryota);7.62625135715208e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.0763533443734e-08!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.2059646341826e-08!GO:0006917;induction of apoptosis;1.75899572705356e-08!GO:0030532;small nuclear ribonucleoprotein complex;1.80100536084264e-08!GO:0046930;pore complex;1.89062160928674e-08!GO:0005789;endoplasmic reticulum membrane;1.89780936044897e-08!GO:0016881;acid-amino acid ligase activity;2.12970631311697e-08!GO:0003712;transcription cofactor activity;2.24024591910848e-08!GO:0006399;tRNA metabolic process;2.64363305612935e-08!GO:0051170;nuclear import;2.78111524715195e-08!GO:0051188;cofactor biosynthetic process;2.91654588498697e-08!GO:0012502;induction of programmed cell death;2.96543604562755e-08!GO:0015078;hydrogen ion transmembrane transporter activity;3.33628044376371e-08!GO:0007243;protein kinase cascade;3.65673421234655e-08!GO:0045786;negative regulation of progression through cell cycle;3.9880415546722e-08!GO:0004298;threonine endopeptidase activity;4.06344764670376e-08!GO:0006606;protein import into nucleus;4.25504735211754e-08!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;4.46954260546884e-08!GO:0016192;vesicle-mediated transport;4.55063024969806e-08!GO:0009055;electron carrier activity;4.61400641361316e-08!GO:0016740;transferase activity;6.08408513746602e-08!GO:0015986;ATP synthesis coupled proton transport;7.29476563685947e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;7.29476563685947e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;9.03576646663953e-08!GO:0048523;negative regulation of cellular process;1.01863775484817e-07!GO:0043065;positive regulation of apoptosis;1.04884830804287e-07!GO:0050789;regulation of biological process;1.15990963520296e-07!GO:0009060;aerobic respiration;1.29367850398741e-07!GO:0051246;regulation of protein metabolic process;1.67965413669528e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.75066922048368e-07!GO:0043068;positive regulation of programmed cell death;1.7635148047325e-07!GO:0016779;nucleotidyltransferase activity;1.78643865767685e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.9518879499019e-07!GO:0051028;mRNA transport;2.03677400682714e-07!GO:0006364;rRNA processing;2.23789242974817e-07!GO:0016072;rRNA metabolic process;2.2505560617147e-07!GO:0016469;proton-transporting two-sector ATPase complex;2.63071372233455e-07!GO:0009142;nucleoside triphosphate biosynthetic process;3.00171400725976e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;3.00171400725976e-07!GO:0065009;regulation of a molecular function;3.40906083616628e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;4.21655592303013e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;4.21655592303013e-07!GO:0005768;endosome;4.63900683104562e-07!GO:0009141;nucleoside triphosphate metabolic process;5.21393120663821e-07!GO:0009199;ribonucleoside triphosphate metabolic process;5.21442544408374e-07!GO:0006261;DNA-dependent DNA replication;5.21442544408374e-07!GO:0006754;ATP biosynthetic process;5.47180341798493e-07!GO:0006753;nucleoside phosphate metabolic process;5.47180341798493e-07!GO:0032446;protein modification by small protein conjugation;6.53508106258424e-07!GO:0019899;enzyme binding;7.16165963854828e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;7.25354551179325e-07!GO:0009144;purine nucleoside triphosphate metabolic process;7.25354551179325e-07!GO:0009056;catabolic process;8.44734710957887e-07!GO:0006461;protein complex assembly;8.75517343776776e-07!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;9.32076456145447e-07!GO:0015399;primary active transmembrane transporter activity;9.32076456145447e-07!GO:0006888;ER to Golgi vesicle-mediated transport;9.44391662221191e-07!GO:0048519;negative regulation of biological process;1.16281523924845e-06!GO:0008632;apoptotic program;1.30853117857135e-06!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.32098908898339e-06!GO:0004812;aminoacyl-tRNA ligase activity;1.32098908898339e-06!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.32098908898339e-06!GO:0016567;protein ubiquitination;1.32806936907008e-06!GO:0030120;vesicle coat;1.36665601806319e-06!GO:0030662;coated vesicle membrane;1.36665601806319e-06!GO:0046034;ATP metabolic process;1.43520517421762e-06!GO:0045333;cellular respiration;1.44332339949544e-06!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.53980397788862e-06!GO:0019222;regulation of metabolic process;1.69212999602316e-06!GO:0007005;mitochondrion organization and biogenesis;1.75637155996672e-06!GO:0045259;proton-transporting ATP synthase complex;1.88139390548662e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;2.64811316750854e-06!GO:0009117;nucleotide metabolic process;2.71079333020151e-06!GO:0051325;interphase;2.72163888762015e-06!GO:0000775;chromosome, pericentric region;2.72163888762015e-06!GO:0009108;coenzyme biosynthetic process;2.9775843738856e-06!GO:0043038;amino acid activation;3.18794870046149e-06!GO:0006418;tRNA aminoacylation for protein translation;3.18794870046149e-06!GO:0043039;tRNA aminoacylation;3.18794870046149e-06!GO:0006310;DNA recombination;3.27876432829311e-06!GO:0000245;spliceosome assembly;4.12936303169942e-06!GO:0048475;coated membrane;4.12936303169942e-06!GO:0030117;membrane coat;4.12936303169942e-06!GO:0051329;interphase of mitotic cell cycle;4.13098812180484e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;4.34646855731335e-06!GO:0006099;tricarboxylic acid cycle;4.53818157830143e-06!GO:0046356;acetyl-CoA catabolic process;4.53818157830143e-06!GO:0005762;mitochondrial large ribosomal subunit;4.65280732824997e-06!GO:0000315;organellar large ribosomal subunit;4.65280732824997e-06!GO:0000151;ubiquitin ligase complex;5.09854258315594e-06!GO:0005793;ER-Golgi intermediate compartment;5.19714373411932e-06!GO:0051168;nuclear export;5.42414507575627e-06!GO:0048522;positive regulation of cellular process;5.54391591996815e-06!GO:0004674;protein serine/threonine kinase activity;6.93343188934053e-06!GO:0005813;centrosome;7.05450642099597e-06!GO:0003713;transcription coactivator activity;8.49568452142612e-06!GO:0016563;transcription activator activity;8.69296926370954e-06!GO:0005819;spindle;9.00528071168476e-06!GO:0006084;acetyl-CoA metabolic process;9.81731514592572e-06!GO:0005815;microtubule organizing center;1.15104624451271e-05!GO:0006613;cotranslational protein targeting to membrane;1.26557386335241e-05!GO:0015630;microtubule cytoskeleton;1.56379425820082e-05!GO:0006401;RNA catabolic process;1.65080599742876e-05!GO:0006752;group transfer coenzyme metabolic process;1.75835280178791e-05!GO:0007242;intracellular signaling cascade;2.06825808076003e-05!GO:0000075;cell cycle checkpoint;2.20248827356508e-05!GO:0003724;RNA helicase activity;2.3940932961595e-05!GO:0043492;ATPase activity, coupled to movement of substances;2.48357776443567e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;2.53595977308341e-05!GO:0005657;replication fork;2.90561046162692e-05!GO:0003690;double-stranded DNA binding;2.90561046162692e-05!GO:0006366;transcription from RNA polymerase II promoter;2.97197528412194e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;3.36410562551496e-05!GO:0005773;vacuole;3.45739301757995e-05!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;3.52750909121566e-05!GO:0009109;coenzyme catabolic process;3.88902594677696e-05!GO:0007088;regulation of mitosis;3.8963595381385e-05!GO:0043623;cellular protein complex assembly;5.48452242293893e-05!GO:0006612;protein targeting to membrane;5.48936151462745e-05!GO:0051187;cofactor catabolic process;6.2993255050869e-05!GO:0031323;regulation of cellular metabolic process;6.422832356073e-05!GO:0006402;mRNA catabolic process;7.81457504254361e-05!GO:0031324;negative regulation of cellular metabolic process;0.000104361934177888!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000105910082421822!GO:0000314;organellar small ribosomal subunit;0.000121437766021783!GO:0005763;mitochondrial small ribosomal subunit;0.000121437766021783!GO:0003684;damaged DNA binding;0.000127151731616394!GO:0008094;DNA-dependent ATPase activity;0.00013069432554571!GO:0000323;lytic vacuole;0.000132266081058182!GO:0005764;lysosome;0.000132266081058182!GO:0050790;regulation of catalytic activity;0.000136457077490759!GO:0065007;biological regulation;0.000142402392847266!GO:0016363;nuclear matrix;0.000157678124954428!GO:0006818;hydrogen transport;0.000164336546080856!GO:0015992;proton transport;0.000164336546080856!GO:0005885;Arp2/3 protein complex;0.000191295460457982!GO:0044431;Golgi apparatus part;0.000201589262203647!GO:0003899;DNA-directed RNA polymerase activity;0.000204174419772333!GO:0005770;late endosome;0.000226475249140653!GO:0005525;GTP binding;0.000226640936486852!GO:0008186;RNA-dependent ATPase activity;0.000263685076896553!GO:0005798;Golgi-associated vesicle;0.000265741193386579!GO:0006302;double-strand break repair;0.000270072062098165!GO:0009967;positive regulation of signal transduction;0.000288715247514638!GO:0051427;hormone receptor binding;0.000304141049939317!GO:0008654;phospholipid biosynthetic process;0.000315402142008434!GO:0009615;response to virus;0.000316412305466208!GO:0005637;nuclear inner membrane;0.000361210434590499!GO:0048518;positive regulation of biological process;0.000377756557101173!GO:0043021;ribonucleoprotein binding;0.000391945363310471!GO:0030384;phosphoinositide metabolic process;0.000416846939025848!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000419107460462159!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000426310138432144!GO:0007006;mitochondrial membrane organization and biogenesis;0.000445447837315013!GO:0006350;transcription;0.000448278373138651!GO:0004518;nuclease activity;0.000450339708179891!GO:0044440;endosomal part;0.000471389940841714!GO:0010008;endosome membrane;0.000471389940841714!GO:0003729;mRNA binding;0.000528580494188617!GO:0051252;regulation of RNA metabolic process;0.000528894906220685!GO:0009892;negative regulation of metabolic process;0.00055730807319198!GO:0008234;cysteine-type peptidase activity;0.000573846132156471!GO:0043681;protein import into mitochondrion;0.000575996935084018!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000585507008763725!GO:0003924;GTPase activity;0.000592635223484153!GO:0016564;transcription repressor activity;0.000596505869170836!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000597477106658597!GO:0035257;nuclear hormone receptor binding;0.000597977169073228!GO:0009165;nucleotide biosynthetic process;0.00061543102746829!GO:0000287;magnesium ion binding;0.000742507600830141!GO:0006417;regulation of translation;0.00075688978825422!GO:0004004;ATP-dependent RNA helicase activity;0.000770929859563064!GO:0000082;G1/S transition of mitotic cell cycle;0.000890253399259009!GO:0006611;protein export from nucleus;0.00095111903207715!GO:0006414;translational elongation;0.000951953049250378!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000998119603974742!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000998119603974742!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000998119603974742!GO:0006289;nucleotide-excision repair;0.00100033763688664!GO:0007050;cell cycle arrest;0.0010181088444327!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00102982313372261!GO:0042110;T cell activation;0.00106913000408891!GO:0048468;cell development;0.0010796885320471!GO:0004527;exonuclease activity;0.00109549379704279!GO:0006891;intra-Golgi vesicle-mediated transport;0.00109549379704279!GO:0005667;transcription factor complex;0.00112785966131911!GO:0007093;mitotic cell cycle checkpoint;0.00118980967856624!GO:0005769;early endosome;0.00119793887319322!GO:0051052;regulation of DNA metabolic process;0.00133066243623899!GO:0006650;glycerophospholipid metabolic process;0.00136021561743336!GO:0000776;kinetochore;0.00136326246256185!GO:0007051;spindle organization and biogenesis;0.00137129958510308!GO:0046489;phosphoinositide biosynthetic process;0.00137336196372345!GO:0045454;cell redox homeostasis;0.00149456037035763!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00153692792545247!GO:0003678;DNA helicase activity;0.00160488487098668!GO:0019867;outer membrane;0.00166661711830587!GO:0003682;chromatin binding;0.00173375887056866!GO:0005741;mitochondrial outer membrane;0.00173422916973188!GO:0032561;guanyl ribonucleotide binding;0.00178380495107481!GO:0019001;guanyl nucleotide binding;0.00178380495107481!GO:0030658;transport vesicle membrane;0.00182954453004629!GO:0010468;regulation of gene expression;0.00186149705454579!GO:0031968;organelle outer membrane;0.00187669151823183!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0020130492473132!GO:0000139;Golgi membrane;0.00202094485456753!GO:0008270;zinc ion binding;0.00204943485577059!GO:0005684;U2-dependent spliceosome;0.00204943485577059!GO:0006091;generation of precursor metabolites and energy;0.00208331997030584!GO:0016853;isomerase activity;0.00222810738711164!GO:0031982;vesicle;0.00229803821294652!GO:0019843;rRNA binding;0.00238318449542895!GO:0022415;viral reproductive process;0.0024073307060547!GO:0007059;chromosome segregation;0.0024501660060813!GO:0006284;base-excision repair;0.0024501660060813!GO:0060090;molecular adaptor activity;0.00248939793299469!GO:0051920;peroxiredoxin activity;0.00253488566180543!GO:0022890;inorganic cation transmembrane transporter activity;0.00257440438620137!GO:0015631;tubulin binding;0.00257440438620137!GO:0051789;response to protein stimulus;0.00261343026089211!GO:0006986;response to unfolded protein;0.00261343026089211!GO:0031326;regulation of cellular biosynthetic process;0.00264281931769348!GO:0046474;glycerophospholipid biosynthetic process;0.00269117389640199!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00269117389640199!GO:0048500;signal recognition particle;0.00292935894029373!GO:0008033;tRNA processing;0.00298353251582892!GO:0042802;identical protein binding;0.0029916213733126!GO:0043281;regulation of caspase activity;0.0029916213733126!GO:0016741;transferase activity, transferring one-carbon groups;0.00299666140018859!GO:0008168;methyltransferase activity;0.00303846231279586!GO:0051223;regulation of protein transport;0.00318975664671245!GO:0044438;microbody part;0.00323071574429785!GO:0044439;peroxisomal part;0.00323071574429785!GO:0006352;transcription initiation;0.00324618236889677!GO:0031072;heat shock protein binding;0.00325294857497444!GO:0046822;regulation of nucleocytoplasmic transport;0.00343494509522826!GO:0005048;signal sequence binding;0.00344878167711749!GO:0003677;DNA binding;0.0036621791812801!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00367561304874572!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00367561304874572!GO:0032508;DNA duplex unwinding;0.00373453607331245!GO:0032392;DNA geometric change;0.00373453607331245!GO:0008637;apoptotic mitochondrial changes;0.00379388085961636!GO:0008624;induction of apoptosis by extracellular signals;0.00417199690747809!GO:0006383;transcription from RNA polymerase III promoter;0.00422604274059182!GO:0009124;nucleoside monophosphate biosynthetic process;0.00447351354156969!GO:0009123;nucleoside monophosphate metabolic process;0.00447351354156969!GO:0031903;microbody membrane;0.00447795644739285!GO:0005778;peroxisomal membrane;0.00447795644739285!GO:0019900;kinase binding;0.00449429563135054!GO:0030660;Golgi-associated vesicle membrane;0.00461478820452225!GO:0051251;positive regulation of lymphocyte activation;0.00471543190469897!GO:0019901;protein kinase binding;0.00479104483790526!GO:0031252;leading edge;0.00480518746571023!GO:0051336;regulation of hydrolase activity;0.00484517034909887!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00491585954607773!GO:0045047;protein targeting to ER;0.00491585954607773!GO:0006405;RNA export from nucleus;0.00509608790612001!GO:0016301;kinase activity;0.00513693156871854!GO:0008312;7S RNA binding;0.0052327612239089!GO:0043488;regulation of mRNA stability;0.0052327612239089!GO:0043487;regulation of RNA stability;0.0052327612239089!GO:0003711;transcription elongation regulator activity;0.00525675085134258!GO:0031988;membrane-bound vesicle;0.00545196640136739!GO:0007265;Ras protein signal transduction;0.00585228099484623!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0059156806662456!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00603684147029016!GO:0006268;DNA unwinding during replication;0.00610489717532966!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.00623541765746349!GO:0006839;mitochondrial transport;0.00625945955458788!GO:0031410;cytoplasmic vesicle;0.00629892237518811!GO:0000209;protein polyubiquitination;0.00642600118927281!GO:0016481;negative regulation of transcription;0.00660581808035814!GO:0006607;NLS-bearing substrate import into nucleus;0.00667034581384654!GO:0007264;small GTPase mediated signal transduction;0.00667323804754666!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00678672240853884!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00697024605008026!GO:0015002;heme-copper terminal oxidase activity;0.00697024605008026!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00697024605008026!GO:0004129;cytochrome-c oxidase activity;0.00697024605008026!GO:0047485;protein N-terminus binding;0.00723383805849893!GO:0051539;4 iron, 4 sulfur cluster binding;0.00724292930959119!GO:0030137;COPI-coated vesicle;0.00727636290628196!GO:0032259;methylation;0.00729176495211351!GO:0016311;dephosphorylation;0.00729210634798015!GO:0030118;clathrin coat;0.00731874140775973!GO:0051540;metal cluster binding;0.00743943237869202!GO:0051536;iron-sulfur cluster binding;0.00743943237869202!GO:0005774;vacuolar membrane;0.00748434879488117!GO:0045936;negative regulation of phosphate metabolic process;0.00750259486137353!GO:0030663;COPI coated vesicle membrane;0.00781756402811586!GO:0030126;COPI vesicle coat;0.00781756402811586!GO:0008629;induction of apoptosis by intracellular signals;0.00794215091864403!GO:0051087;chaperone binding;0.00799339647050279!GO:0030176;integral to endoplasmic reticulum membrane;0.00811027270931718!GO:0031124;mRNA 3'-end processing;0.00816746951960904!GO:0043596;nuclear replication fork;0.00816746951960904!GO:0006626;protein targeting to mitochondrion;0.00817374225172229!GO:0016788;hydrolase activity, acting on ester bonds;0.00828328411536615!GO:0016197;endosome transport;0.00833111948933085!GO:0006497;protein amino acid lipidation;0.00839172476849222!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00839172476849222!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00839452068293527!GO:0033116;ER-Golgi intermediate compartment membrane;0.00863223900617793!GO:0006506;GPI anchor biosynthetic process;0.00880443256932749!GO:0044452;nucleolar part;0.00887941990101629!GO:0001772;immunological synapse;0.00899420990713857!GO:0042770;DNA damage response, signal transduction;0.00921292256602833!GO:0016251;general RNA polymerase II transcription factor activity;0.00930877788098484!GO:0006505;GPI anchor metabolic process;0.00948184077765623!GO:0043621;protein self-association;0.00963929474514744!GO:0042393;histone binding;0.0099142870239385!GO:0003714;transcription corepressor activity;0.0099142870239385!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0099142870239385!GO:0010257;NADH dehydrogenase complex assembly;0.0099142870239385!GO:0033108;mitochondrial respiratory chain complex assembly;0.0099142870239385!GO:0042101;T cell receptor complex;0.00992648535264474!GO:0008139;nuclear localization sequence binding;0.00992648535264474!GO:0016584;nucleosome positioning;0.0099966641441047!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0100998480630571!GO:0000228;nuclear chromosome;0.0101160176955503!GO:0016605;PML body;0.0101501518851373!GO:0009161;ribonucleoside monophosphate metabolic process;0.010225579152313!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.010225579152313!GO:0006595;polyamine metabolic process;0.0103154127560264!GO:0048487;beta-tubulin binding;0.0105996198656947!GO:0043414;biopolymer methylation;0.0109807382276273!GO:0003746;translation elongation factor activity;0.011045306770367!GO:0016023;cytoplasmic membrane-bound vesicle;0.0113274353351163!GO:0015980;energy derivation by oxidation of organic compounds;0.0113292552583684!GO:0008022;protein C-terminus binding;0.0114053580959893!GO:0030518;steroid hormone receptor signaling pathway;0.0114760105887899!GO:0006338;chromatin remodeling;0.0115170382014807!GO:0046483;heterocycle metabolic process;0.0119119897181067!GO:0004177;aminopeptidase activity;0.0120043224168037!GO:0051092;activation of NF-kappaB transcription factor;0.0121323828282277!GO:0048471;perinuclear region of cytoplasm;0.0122787708762133!GO:0009889;regulation of biosynthetic process;0.0124164181973631!GO:0000059;protein import into nucleus, docking;0.0124446209517899!GO:0051881;regulation of mitochondrial membrane potential;0.0124481228694215!GO:0006919;caspase activation;0.012797063145374!GO:0016491;oxidoreductase activity;0.0132358213465905!GO:0032774;RNA biosynthetic process;0.0133832494714155!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.0134558461071327!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.0135006392266277!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0135006392266277!GO:0030880;RNA polymerase complex;0.0135006392266277!GO:0032940;secretion by cell;0.0137006680991044!GO:0016791;phosphoric monoester hydrolase activity;0.0137014525380197!GO:0031902;late endosome membrane;0.0137941513169902!GO:0019210;kinase inhibitor activity;0.0138249011952991!GO:0030127;COPII vesicle coat;0.0139786194381886!GO:0012507;ER to Golgi transport vesicle membrane;0.0139786194381886!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0143497869840537!GO:0006779;porphyrin biosynthetic process;0.0143497869840537!GO:0033014;tetrapyrrole biosynthetic process;0.0143497869840537!GO:0004532;exoribonuclease activity;0.014372051641449!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.014372051641449!GO:0016859;cis-trans isomerase activity;0.014372051641449!GO:0050870;positive regulation of T cell activation;0.0145765686516294!GO:0000049;tRNA binding;0.0146928998049847!GO:0044437;vacuolar part;0.0148239088320697!GO:0051235;maintenance of localization;0.0149720176071371!GO:0016272;prefoldin complex;0.0149825519283398!GO:0030134;ER to Golgi transport vesicle;0.0150872360589166!GO:0046914;transition metal ion binding;0.0151291530816195!GO:0005788;endoplasmic reticulum lumen;0.0152023153814318!GO:0006351;transcription, DNA-dependent;0.0153412082180559!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0155697617347465!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0156528586458906!GO:0005869;dynactin complex;0.0156795267812685!GO:0042326;negative regulation of phosphorylation;0.015751591209915!GO:0045045;secretory pathway;0.015751591209915!GO:0006950;response to stress;0.015751591209915!GO:0030521;androgen receptor signaling pathway;0.015751591209915!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0159255317750649!GO:0001836;release of cytochrome c from mitochondria;0.0159258734998551!GO:0009112;nucleobase metabolic process;0.0159762224325869!GO:0004576;oligosaccharyl transferase activity;0.016087273535541!GO:0046966;thyroid hormone receptor binding;0.01609865833384!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0161323832850548!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0161323832850548!GO:0009126;purine nucleoside monophosphate metabolic process;0.0161323832850548!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0161323832850548!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0162159930258162!GO:0006778;porphyrin metabolic process;0.01645278807521!GO:0033013;tetrapyrrole metabolic process;0.01645278807521!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.01645278807521!GO:0046467;membrane lipid biosynthetic process;0.016468820663958!GO:0005765;lysosomal membrane;0.0167703124368988!GO:0007052;mitotic spindle organization and biogenesis;0.0174346320279158!GO:0004860;protein kinase inhibitor activity;0.0174346320279158!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0176538139506093!GO:0030867;rough endoplasmic reticulum membrane;0.0176793309631685!GO:0005777;peroxisome;0.0176837785283949!GO:0042579;microbody;0.0176837785283949!GO:0045792;negative regulation of cell size;0.0178370655260126!GO:0008408;3'-5' exonuclease activity;0.017888052804136!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0186041564765249!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0186041564765249!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0186041564765249!GO:0046426;negative regulation of JAK-STAT cascade;0.0187611729146503!GO:0030308;negative regulation of cell growth;0.0190027021478137!GO:0019079;viral genome replication;0.0193298409184338!GO:0030125;clathrin vesicle coat;0.0195351715883199!GO:0030665;clathrin coated vesicle membrane;0.0195351715883199!GO:0000339;RNA cap binding;0.0195847661343931!GO:0031123;RNA 3'-end processing;0.0196412179051305!GO:0019904;protein domain specific binding;0.0200126024267092!GO:0009116;nucleoside metabolic process;0.02041829504121!GO:0005521;lamin binding;0.0204702537311091!GO:0045449;regulation of transcription;0.0205932504047433!GO:0051090;regulation of transcription factor activity;0.0206141037714737!GO:0019318;hexose metabolic process;0.0208385476407752!GO:0008017;microtubule binding;0.0213321596965716!GO:0035258;steroid hormone receptor binding;0.0215141378801952!GO:0005996;monosaccharide metabolic process;0.0217513576034133!GO:0046649;lymphocyte activation;0.0217914547013448!GO:0005070;SH3/SH2 adaptor activity;0.0219083334031053!GO:0043022;ribosome binding;0.0219083334031053!GO:0030695;GTPase regulator activity;0.0219668735827597!GO:0043280;positive regulation of caspase activity;0.0219946871946464!GO:0000922;spindle pole;0.0223290670045701!GO:0005669;transcription factor TFIID complex;0.0223290670045701!GO:0031625;ubiquitin protein ligase binding;0.0223761475125497!GO:0004722;protein serine/threonine phosphatase activity;0.022380927662301!GO:0019783;small conjugating protein-specific protease activity;0.0224305597621984!GO:0042158;lipoprotein biosynthetic process;0.0224366748608721!GO:0030522;intracellular receptor-mediated signaling pathway;0.0229671776597565!GO:0006914;autophagy;0.0237405254172449!GO:0051059;NF-kappaB binding;0.0237734475591804!GO:0004003;ATP-dependent DNA helicase activity;0.0239172037031512!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0241059855726646!GO:0000428;DNA-directed RNA polymerase complex;0.0241059855726646!GO:0051098;regulation of binding;0.0245481226333371!GO:0040029;regulation of gene expression, epigenetic;0.0248026394816787!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0249199369538228!GO:0008250;oligosaccharyl transferase complex;0.0249199369538228!GO:0006007;glucose catabolic process;0.0249199369538228!GO:0050865;regulation of cell activation;0.0249868891535949!GO:0044454;nuclear chromosome part;0.0249868891535949!GO:0008320;protein transmembrane transporter activity;0.0251176972492027!GO:0051249;regulation of lymphocyte activation;0.0256139761583006!GO:0004843;ubiquitin-specific protease activity;0.0259858216335145!GO:0016790;thiolester hydrolase activity;0.0260728077998165!GO:0030132;clathrin coat of coated pit;0.0260765793646578!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0261043024123186!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0261066002696119!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0261066002696119!GO:0044262;cellular carbohydrate metabolic process;0.0261317112751824!GO:0043601;nuclear replisome;0.0264147987237423!GO:0030894;replisome;0.0264147987237423!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0268076796944731!GO:0007259;JAK-STAT cascade;0.0270607364367161!GO:0045926;negative regulation of growth;0.0272612308012878!GO:0008047;enzyme activator activity;0.0278878974253387!GO:0018193;peptidyl-amino acid modification;0.0281177154047287!GO:0030433;ER-associated protein catabolic process;0.0283654575608825!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0283654575608825!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0283979046871364!GO:0050811;GABA receptor binding;0.0286128340703341!GO:0005031;tumor necrosis factor receptor activity;0.0289218118216731!GO:0006740;NADPH regeneration;0.029164109964535!GO:0006098;pentose-phosphate shunt;0.029164109964535!GO:0000792;heterochromatin;0.0294084224447471!GO:0048002;antigen processing and presentation of peptide antigen;0.0303604540163367!GO:0043284;biopolymer biosynthetic process;0.0305278330535153!GO:0030833;regulation of actin filament polymerization;0.0307208655860638!GO:0006984;ER-nuclear signaling pathway;0.0309625299601373!GO:0050852;T cell receptor signaling pathway;0.0312123796875316!GO:0022884;macromolecule transmembrane transporter activity;0.0316573433250658!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0316573433250658!GO:0017134;fibroblast growth factor binding;0.0318056791350634!GO:0004197;cysteine-type endopeptidase activity;0.0318558878430312!GO:0032200;telomere organization and biogenesis;0.0324812817346993!GO:0000723;telomere maintenance;0.0324812817346993!GO:0000178;exosome (RNase complex);0.0326431073018841!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0326431073018841!GO:0046979;TAP2 binding;0.0328470991657434!GO:0046977;TAP binding;0.0328470991657434!GO:0046978;TAP1 binding;0.0328470991657434!GO:0042608;T cell receptor binding;0.0328470991657434!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.0345000587405071!GO:0006635;fatty acid beta-oxidation;0.0347043483650467!GO:0050863;regulation of T cell activation;0.0351305253868404!GO:0009966;regulation of signal transduction;0.0354742319525409!GO:0006783;heme biosynthetic process;0.0361638603056225!GO:0000152;nuclear ubiquitin ligase complex;0.0361638603056225!GO:0006266;DNA ligation;0.0361638603056225!GO:0005083;small GTPase regulator activity;0.0363372008515388!GO:0030041;actin filament polymerization;0.0365188742738938!GO:0006144;purine base metabolic process;0.0365199464167947!GO:0005832;chaperonin-containing T-complex;0.0365339382570191!GO:0030258;lipid modification;0.0367207680755827!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0368173617009516!GO:0045061;thymic T cell selection;0.0368825503428643!GO:0022406;membrane docking;0.0368825503428643!GO:0048278;vesicle docking;0.0368825503428643!GO:0006378;mRNA polyadenylation;0.036902125604736!GO:0007034;vacuolar transport;0.0370835418156878!GO:0016569;covalent chromatin modification;0.0373276324853512!GO:0008276;protein methyltransferase activity;0.0376922923413515!GO:0004221;ubiquitin thiolesterase activity;0.0378976312971575!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0378976312971575!GO:0000738;DNA catabolic process, exonucleolytic;0.0379893290128052!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0380300414580361!GO:0006458;'de novo' protein folding;0.0381374955838291!GO:0051084;'de novo' posttranslational protein folding;0.0381374955838291!GO:0019058;viral infectious cycle;0.0385179004020239!GO:0048524;positive regulation of viral reproduction;0.0388460725012089!GO:0006376;mRNA splice site selection;0.0398876608138577!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0398876608138577!GO:0044450;microtubule organizing center part;0.0399724439843029!GO:0031647;regulation of protein stability;0.0400289042313713!GO:0016860;intramolecular oxidoreductase activity;0.0400519112792991!GO:0006013;mannose metabolic process;0.0403349904223471!GO:0042168;heme metabolic process;0.0405237975571097!GO:0005784;translocon complex;0.0409825282673395!GO:0030133;transport vesicle;0.0412339938823206!GO:0030119;AP-type membrane coat adaptor complex;0.04219724055177!GO:0000781;chromosome, telomeric region;0.0422626744008034!GO:0051452;cellular pH reduction;0.0426658963629572!GO:0051453;regulation of cellular pH;0.0426658963629572!GO:0045851;pH reduction;0.0426658963629572!GO:0000725;recombinational repair;0.0426658963629572!GO:0000724;double-strand break repair via homologous recombination;0.0426658963629572!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.042829950023118!GO:0006275;regulation of DNA replication;0.042829950023118!GO:0006672;ceramide metabolic process;0.043056006593542!GO:0008213;protein amino acid alkylation;0.0432793040171578!GO:0006479;protein amino acid methylation;0.0432793040171578!GO:0000910;cytokinesis;0.0439941355583093!GO:0000096;sulfur amino acid metabolic process;0.0441010933580129!GO:0000018;regulation of DNA recombination;0.0441806434159544!GO:0019976;interleukin-2 binding;0.0441806434159544!GO:0004911;interleukin-2 receptor activity;0.0441806434159544!GO:0043027;caspase inhibitor activity;0.0446085342595592!GO:0006904;vesicle docking during exocytosis;0.0448174799336807!GO:0030332;cyclin binding;0.0448405268722785!GO:0050178;phenylpyruvate tautomerase activity;0.0452307178205421!GO:0006470;protein amino acid dephosphorylation;0.045678712370554!GO:0006468;protein amino acid phosphorylation;0.0456886800098595!GO:0016408;C-acyltransferase activity;0.0458230976578377!GO:0005652;nuclear lamina;0.0458495999437187!GO:0003725;double-stranded RNA binding;0.0460668387588116!GO:0006270;DNA replication initiation;0.0460680649821879!GO:0004721;phosphoprotein phosphatase activity;0.0469712914466772!GO:0051219;phosphoprotein binding;0.0473233693673439!GO:0007346;regulation of progression through mitotic cell cycle;0.0475099240916917!GO:0031570;DNA integrity checkpoint;0.0475511911654065!GO:0030131;clathrin adaptor complex;0.0475679293851078!GO:0045309;protein phosphorylated amino acid binding;0.0477376720825551!GO:0051338;regulation of transferase activity;0.0478369454188074!GO:0045185;maintenance of protein localization;0.0483817617747148!GO:0001784;phosphotyrosine binding;0.0486357173155002!GO:0007040;lysosome organization and biogenesis;0.0486401248584397!GO:0003887;DNA-directed DNA polymerase activity;0.0496965867947433 | |||
|sample_id=11917 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=CDX1,2,4:3.11001094298;PAX4:2.24567056145;ZBTB16:2.06882886046;ELF1,2,4:1.99669613662;FOXP1:1.98069459248;IKZF2:1.97929463858;PAX3,7:1.83143189526;PITX1..3:1.81613952657;RUNX1..3:1.74351701807;NKX6-1,2:1.71357003498;TLX2:1.49197283798;POU1F1:1.43563262123;ETS1,2:1.39867365457;STAT1,3:1.2723543365;DMAP1_NCOR{1,2}_SMARC:1.27220492024;PDX1:1.15120933888;SPI1:1.14044712124;POU2F1..3:1.13756097294;TOPORS:1.07767323404;NKX3-1:1.02916555776;IRF1,2:1.01044144149;E2F1..5:0.992994841053;ELK1,4_GABP{A,B1}:0.979362537235;SPZ1:0.954752207834;PBX1:0.947806144289;NKX2-2,8:0.904170133495;RORA:0.87171974374;NKX2-1,4:0.845062640551;SPIB:0.838072080264;BREu{core}:0.742175412985;GATA6:0.710304527092;FOXO1,3,4:0.6554146712;YY1:0.646273417029;HOX{A6,A7,B6,B7}:0.630240929396;NANOG{mouse}:0.62289444935;TGIF1:0.605078344644;NFY{A,B,C}:0.562389491849;FOX{F1,F2,J1}:0.472325442893;ALX1:0.456495635592;BPTF:0.453554675956;AIRE:0.452055307798;FOX{I1,J2}:0.386005280518;LEF1_TCF7_TCF7L1,2:0.385954286243;FOX{D1,D2}:0.37008928713;FOXD3:0.336179469647;IRF7:0.328184768762;SOX5:0.3187559866;T:0.311811686534;RXRA_VDR{dimer}:0.25099675304;SNAI1..3:0.245135520067;OCT4_SOX2{dimer}:0.238137765252;CRX:0.198261457519;PAX6:0.193503691512;CREB1:0.180382742625;NFKB1_REL_RELA:0.180113713963;ZEB1:0.172584943493;MYOD1:0.136496045273;ATF5_CREB3:0.127950348461;MYB:0.109876270095;LMO2:0.0977499222588;STAT2,4,6:0.0890508075616;GFI1:0.0850977168369;POU3F1..4:0.0717969268294;NR5A1,2:0.061168449013;ATF6:0.0522310474888;FOXN1:0.0503205885551;NRF1:0.0453360708909;HAND1,2:0.0281572156595;PAX2:-0.00594804360111;FOXQ1:-0.0183270777757;HES1:-0.0445224668777;NR3C1:-0.0450826036895;FOXM1:-0.0595347419552;CUX2:-0.0622594499862;SREBF1,2:-0.0645757340713;HNF4A_NR2F1,2:-0.0859648393475;GCM1,2:-0.0893141070322;EVI1:-0.093912405077;ZNF143:-0.101732661089;AR:-0.109832898838;FOXA2:-0.126651266807;NFIL3:-0.159022292042;TFDP1:-0.223816588189;NFE2L1:-0.273335384181;DBP:-0.280221552958;ATF4:-0.290801805517;SOX{8,9,10}:-0.300820134186;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.318233387138;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.324735705239;AHR_ARNT_ARNT2:-0.328573746415;ZNF384:-0.334037220631;RFX2..5_RFXANK_RFXAP:-0.338792877308;STAT5{A,B}:-0.340714180584;HNF1A:-0.345182732721;HBP1_HMGB_SSRP1_UBTF:-0.345607848979;PAX8:-0.384956617103;SMAD1..7,9:-0.40304937948;NR1H4:-0.416563242358;JUN:-0.41757495625;GLI1..3:-0.424581128536;POU5F1:-0.43275589882;MYFfamily:-0.451892699804;RREB1:-0.458738065895;PRRX1,2:-0.461405448761;ATF2:-0.463838265069;ARID5B:-0.475603194238;NR6A1:-0.506771949522;HMX1:-0.527818714065;TP53:-0.557682912279;REST:-0.558234104763;TAL1_TCF{3,4,12}:-0.560134624293;NKX2-3_NKX2-5:-0.574494811374;NFATC1..3:-0.578242320309;ZNF148:-0.593035825082;SOX2:-0.59610098444;UFEwm:-0.599478695326;BACH2:-0.613319196495;CEBPA,B_DDIT3:-0.643153631689;SRF:-0.651002431067;EP300:-0.65704282654;FOXP3:-0.673996940863;ESR1:-0.681760756077;VSX1,2:-0.706351507603;ADNP_IRX_SIX_ZHX:-0.713487483384;ZNF238:-0.726934043441;PAX5:-0.727612733488;FOXL1:-0.745307415688;FOS_FOS{B,L1}_JUN{B,D}:-0.749233947189;TFAP4:-0.749442710679;CDC5L:-0.755637137949;ONECUT1,2:-0.763760493053;PPARG:-0.799562167712;NFE2:-0.812871405998;XCPE1{core}:-0.839655247377;MEF2{A,B,C,D}:-0.846061799344;HOXA9_MEIS1:-0.890922201911;MYBL2:-0.906169067591;EBF1:-0.914248311307;MED-1{core}:-0.932500425547;LHX3,4:-0.944473796622;ZFP161:-0.952750079969;HLF:-0.953157039253;FOSL2:-0.955523451731;MZF1:-0.971246562293;ALX4:-0.971955540351;TFCP2:-0.985014973194;RFX1:-0.985416416266;ZBTB6:-1.01330889874;EGR1..3:-1.01816939362;NFE2L2:-1.0301299113;NHLH1,2:-1.07361048123;PRDM1:-1.08179661201;SOX17:-1.0867782265;KLF4:-1.11585844216;ZNF423:-1.11960788867;bHLH_family:-1.12129077196;HIF1A:-1.12774722243;NANOG:-1.16110799894;TFAP2B:-1.16859003666;HIC1:-1.17519523581;POU6F1:-1.18198448797;HMGA1,2:-1.22265270572;GFI1B:-1.23314234608;GATA4:-1.24098725675;RBPJ:-1.24467086628;MTE{core}:-1.34840712545;NFIX:-1.36142140949;HOX{A4,D4}:-1.39938057426;MTF1:-1.40348774571;TEF:-1.42335028749;PATZ1:-1.44398686591;MAZ:-1.45261036449;TBX4,5:-1.4626081507;TBP:-1.47651277618;GZF1:-1.48479481773;GTF2I:-1.48957880873;GTF2A1,2:-1.50924049376;ESRRA:-1.52819434933;HSF1,2:-1.54115646063;MAFB:-1.58442779884;TFAP2{A,C}:-1.58581815647;PAX1,9:-1.60029227199;TEAD1:-1.63079560987;HOX{A5,B5}:-1.65898643318;RXR{A,B,G}:-1.6650163034;EN1,2:-1.73255511564;XBP1:-1.74976470712;ZIC1..3:-1.80225854276;SP1:-1.84249074056;IKZF1:-1.84738015723;NKX3-2:-1.93512863669;TLX1..3_NFIC{dimer}:-2.00325198928 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11917-125G9;search_select_hide=table117:FF:11917-125G9 | |||
}} | }} |
Latest revision as of 18:29, 4 June 2020
Name: | CD4+CD25-CD45RA+ naive conventional T cells expanded, donor3 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13814 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13814
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13814
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0806 |
10 | 10 | 0.00508 |
100 | 100 | 0.469 |
101 | 101 | 0.0952 |
102 | 102 | 0.473 |
103 | 103 | 0.799 |
104 | 104 | 0.589 |
105 | 105 | 0.255 |
106 | 106 | 0.41 |
107 | 107 | 0.462 |
108 | 108 | 0.846 |
109 | 109 | 0.108 |
11 | 11 | 0.0398 |
110 | 110 | 0.395 |
111 | 111 | 0.27 |
112 | 112 | 0.285 |
113 | 113 | 0.318 |
114 | 114 | 0.439 |
115 | 115 | 0.27 |
116 | 116 | 0.515 |
117 | 117 | 0.00407 |
118 | 118 | 0.357 |
119 | 119 | 0.551 |
12 | 12 | 0.581 |
120 | 120 | 0.782 |
121 | 121 | 0.964 |
122 | 122 | 0.669 |
123 | 123 | 6.73911e-7 |
124 | 124 | 0.334 |
125 | 125 | 0.948 |
126 | 126 | 0.463 |
127 | 127 | 0.725 |
128 | 128 | 0.751 |
129 | 129 | 0.339 |
13 | 13 | 0.469 |
130 | 130 | 0.659 |
131 | 131 | 0.62 |
132 | 132 | 0.61 |
133 | 133 | 0.364 |
134 | 134 | 0.668 |
135 | 135 | 0.837 |
136 | 136 | 0.721 |
137 | 137 | 0.243 |
138 | 138 | 0.317 |
139 | 139 | 0.194 |
14 | 14 | 0.491 |
140 | 140 | 0.019 |
141 | 141 | 0.539 |
142 | 142 | 0.701 |
143 | 143 | 0.00451 |
144 | 144 | 0.442 |
145 | 145 | 0.135 |
146 | 146 | 0.662 |
147 | 147 | 0.216 |
148 | 148 | 0.0613 |
149 | 149 | 0.868 |
15 | 15 | 0.273 |
150 | 150 | 0.603 |
151 | 151 | 0.542 |
152 | 152 | 0.339 |
153 | 153 | 0.932 |
154 | 154 | 0.496 |
155 | 155 | 0.0623 |
156 | 156 | 0.851 |
157 | 157 | 0.19 |
158 | 158 | 0.22 |
159 | 159 | 0.505 |
16 | 16 | 0.729 |
160 | 160 | 0.287 |
161 | 161 | 0.168 |
162 | 162 | 0.447 |
163 | 163 | 0.287 |
164 | 164 | 0.0628 |
165 | 165 | 0.642 |
166 | 166 | 0.78 |
167 | 167 | 0.139 |
168 | 168 | 0.628 |
169 | 169 | 0.344 |
17 | 17 | 0.915 |
18 | 18 | 0.981 |
19 | 19 | 0.645 |
2 | 2 | 0.912 |
20 | 20 | 0.522 |
21 | 21 | 0.168 |
22 | 22 | 0.834 |
23 | 23 | 0.504 |
24 | 24 | 0.932 |
25 | 25 | 0.0669 |
26 | 26 | 0.0335 |
27 | 27 | 0.239 |
28 | 28 | 0.712 |
29 | 29 | 0.0148 |
3 | 3 | 0.0389 |
30 | 30 | 0.08 |
31 | 31 | 0.991 |
32 | 32 | 0.526 |
33 | 33 | 0.643 |
34 | 34 | 0.938 |
35 | 35 | 0.224 |
36 | 36 | 0.0188 |
37 | 37 | 0.297 |
38 | 38 | 0.544 |
39 | 39 | 0.36 |
4 | 4 | 0.968 |
40 | 40 | 0.289 |
41 | 41 | 0.74 |
42 | 42 | 0.0931 |
43 | 43 | 0.397 |
44 | 44 | 0.502 |
45 | 45 | 0.412 |
46 | 46 | 0.11 |
47 | 47 | 0.0163 |
48 | 48 | 0.0469 |
49 | 49 | 0.0982 |
5 | 5 | 0.795 |
50 | 50 | 1 |
51 | 51 | 0.716 |
52 | 52 | 0.347 |
53 | 53 | 0.117 |
54 | 54 | 0.794 |
55 | 55 | 0.595 |
56 | 56 | 0.4 |
57 | 57 | 0.177 |
58 | 58 | 0.0814 |
59 | 59 | 0.422 |
6 | 6 | 0.394 |
60 | 60 | 0.496 |
61 | 61 | 0.128 |
62 | 62 | 0.0538 |
63 | 63 | 0.357 |
64 | 64 | 0.154 |
65 | 65 | 0.787 |
66 | 66 | 0.672 |
67 | 67 | 0.515 |
68 | 68 | 0.958 |
69 | 69 | 0.986 |
7 | 7 | 0.238 |
70 | 70 | 0.111 |
71 | 71 | 0.0308 |
72 | 72 | 0.17 |
73 | 73 | 0.546 |
74 | 74 | 0.538 |
75 | 75 | 0.0125 |
76 | 76 | 0.195 |
77 | 77 | 0.41 |
78 | 78 | 0.0155 |
79 | 79 | 0.499 |
8 | 8 | 0.432 |
80 | 80 | 0.248 |
81 | 81 | 0.343 |
82 | 82 | 0.0926 |
83 | 83 | 0.407 |
84 | 84 | 0.0336 |
85 | 85 | 0.702 |
86 | 86 | 0.248 |
87 | 87 | 0.663 |
88 | 88 | 0.796 |
89 | 89 | 0.237 |
9 | 9 | 0.871 |
90 | 90 | 0.049 |
91 | 91 | 0.274 |
92 | 92 | 0.451 |
93 | 93 | 0.309 |
94 | 94 | 0.144 |
95 | 95 | 0.0121 |
96 | 96 | 0.176 |
97 | 97 | 0.239 |
98 | 98 | 0.402 |
99 | 99 | 0.367 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13814
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000002 in vivo cell sample
FF:0000210 human sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
NA