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{{Coexpression_clusters
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4766,MA0130.1;0,MA0131.1;1.06461,MA0132.1;0,MA0133.1;0,MA0135.1;1.35921,MA0136.1;0.948776,MA0139.1;1.12079,MA0140.1;0.894983,MA0141.1;0.712476,MA0142.1;1.12317,MA0143.1;2.29531,MA0144.1;0.531867,MA0145.1;0.273764,MA0146.1;1.70974,MA0147.1;0.565108,MA0148.1;3.29283,MA0149.1;0.884158,MA0062.2;1.141,MA0035.2;0.894194,MA0039.2;0.195278,MA0138.2;1.04628,MA0002.2;0.476938,MA0137.2;0.666381,MA0104.2;0.491226,MA0047.2;3.66129,MA0112.2;0.264678,MA0065.2;2.97249,MA0150.1;0.744617,MA0151.1;0,MA0152.1;0.902317,MA0153.1;1.43021,MA0154.1;2.30945,MA0155.1;3.71118,MA0156.1;0.669101,MA0157.1;1.09377,MA0158.1;0,MA0159.1;1.38935,MA0160.1;0.871361,MA0161.1;0,MA0162.1;0.149099,MA0163.1;0.122425,MA0164.1;1.01792,MA0080.2;0.643061,MA0018.2;0.987913,MA0099.2;0.902716,MA0079.2;0.311277,MA0102.2;1.88331,MA0258.1;0.519674,MA0259.1;0.575594,MA0442.1;0}}
|full_id=C3855_hairy_argyrophil_merkel_small_Alveolar_optic_substantia
|id=C3855
|ontology_enrichment_celltype=CL:0002076!1.58e-08!43;CL:0000223!1.10e-07!59
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0007023!5.76e-40!115;UBERON:0000153!1.73e-26!129;UBERON:0007811!1.73e-26!129;UBERON:0000033!2.79e-25!123;UBERON:0001049!5.81e-23!57;UBERON:0005068!5.81e-23!57;UBERON:0006241!5.81e-23!57;UBERON:0007135!5.81e-23!57;UBERON:0004121!1.42e-20!169;UBERON:0003075!2.54e-20!86;UBERON:0007284!2.54e-20!86;UBERON:0000955!2.92e-20!69;UBERON:0006238!2.92e-20!69;UBERON:0001017!4.94e-20!82;UBERON:0003080!7.87e-20!42;UBERON:0002616!1.10e-19!59;UBERON:0003056!1.85e-19!61;UBERON:0002780!1.99e-19!41;UBERON:0001890!1.99e-19!41;UBERON:0006240!1.99e-19!41;UBERON:0000924!2.29e-19!173;UBERON:0006601!2.29e-19!173;UBERON:0005743!4.67e-19!86;UBERON:0002346!1.85e-18!90;UBERON:0000073!8.48e-18!94;UBERON:0001016!8.48e-18!94;UBERON:0002020!2.35e-17!34;UBERON:0003528!2.35e-17!34;UBERON:0001893!3.08e-17!34;UBERON:0002791!1.31e-16!33;UBERON:0001869!1.60e-15!32;UBERON:0000475!5.09e-14!365;UBERON:0000064!1.38e-12!219;UBERON:0002619!1.94e-11!22;UBERON:0000481!3.43e-11!347;UBERON:0000956!5.04e-11!25;UBERON:0000203!5.04e-11!25;UBERON:0000483!1.61e-10!309;UBERON:0001950!2.82e-10!20;UBERON:0000119!4.27e-10!312;UBERON:0004111!1.62e-09!241;UBERON:0000922!2.69e-09!612;UBERON:0000062!1.03e-08!511;UBERON:0001004!1.72e-08!72;UBERON:0000477!2.28e-08!286;UBERON:0002308!2.93e-08!9;UBERON:0000125!2.93e-08!9;UBERON:0004119!3.55e-08!169;UBERON:0000925!3.55e-08!169;UBERON:0006595!3.55e-08!169;UBERON:0000480!3.81e-08!626;UBERON:0000467!8.07e-08!625;UBERON:0002420!9.56e-08!9;UBERON:0007245!9.56e-08!9;UBERON:0010009!9.56e-08!9;UBERON:0010011!9.56e-08!9;UBERON:0000454!9.56e-08!9;UBERON:0000468!9.76e-08!659;UBERON:0002298!1.16e-07!8;UBERON:0002050!1.20e-07!605;UBERON:0005423!1.20e-07!605;UBERON:0000161!2.11e-07!35;UBERON:0000923!2.30e-07!604;UBERON:0005291!2.30e-07!604;UBERON:0006598!2.30e-07!604;UBERON:0002532!2.30e-07!604
}}

Latest revision as of 12:34, 17 September 2013


Full id: C3855_hairy_argyrophil_merkel_small_Alveolar_optic_substantia



Phase1 CAGE Peaks

Hg19::chr1:1356628..1356678,-p1@ANKRD65
Hg19::chr1:1356682..1356700,-p4@ANKRD65
Hg19::chr1:1356719..1356730,-p6@ANKRD65


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
endo-epithelial cell8.02e-1242
endodermal cell6.28e-1158
respiratory epithelial cell2.37e-0713
epithelial cell of alimentary canal2.69e-0720
Uber Anatomy
Ontology termp-valuen
adult organism9.95e-31114
neural plate2.47e-1682
presumptive neural plate2.47e-1682
neural tube2.50e-1656
neural rod2.50e-1656
future spinal cord2.50e-1656
neural keel2.50e-1656
ecto-epithelium1.33e-15104
organ system subdivision1.82e-15223
regional part of nervous system2.65e-1553
regional part of brain2.65e-1553
neurectoderm6.36e-1586
pre-chordal neural plate2.19e-1461
brain5.19e-1468
future brain5.19e-1468
organ part2.22e-13218
brain grey matter4.00e-1334
gray matter4.00e-1334
regional part of forebrain4.81e-1341
forebrain4.81e-1341
anterior neural tube4.81e-1341
future forebrain4.81e-1341
telencephalon4.94e-1334
central nervous system1.87e-1281
ectoderm-derived structure6.16e-12171
ectoderm6.16e-12171
presumptive ectoderm6.16e-12171
regional part of telencephalon1.50e-1132
nervous system1.67e-1189
cerebral hemisphere2.79e-1132
multi-tissue structure3.72e-11342
anatomical cluster1.83e-10373
respiratory system1.10e-0974
anterior region of body2.73e-0962
craniocervical region2.73e-0962
anatomical conduit3.49e-09240
structure with developmental contribution from neural crest5.39e-09132
endoderm-derived structure1.23e-08160
endoderm1.23e-08160
presumptive endoderm1.23e-08160
regional part of cerebral cortex2.44e-0822
epithelium3.17e-08306
neocortex3.72e-0820
cell layer6.22e-08309
cerebral cortex8.82e-0825
pallium8.82e-0825
urothelium9.06e-085
head9.31e-0856
neural nucleus1.53e-079
nucleus of brain1.53e-079
embryo1.86e-07592
respiratory tract4.34e-0754
anatomical group6.45e-07625
brainstem7.80e-076
organ7.81e-07503
orifice7.94e-0736
multi-cellular organism9.08e-07656


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.708947
MA0004.10.826076
MA0006.10.639288
MA0007.10.804807
MA0009.11.3275
MA0014.10.118426
MA0017.10.686276
MA0019.10.990656
MA0024.11.21731
MA0025.11.46617
MA0027.12.95767
MA0028.10.658629
MA0029.11.23771
MA0030.11.22561
MA0031.12.60497
MA0038.10.94098
MA0040.11.24388
MA0041.10.847069
MA0042.10.810843
MA0043.11.32783
MA0046.11.31611
MA0048.11.62115
MA0050.10.81185
MA0051.10.936307
MA0052.11.24796
MA0055.10.190716
MA0056.10
MA0057.10.333427
MA0058.10.716037
MA0059.10.714521
MA0060.10.492218
MA0061.10.456531
MA0063.10
MA0066.10.941452
MA0067.11.65513
MA0068.10.405474
MA0069.11.31207
MA0070.11.30033
MA0071.10.897953
MA0072.11.29561
MA0073.10.0185922
MA0074.12.15449
MA0076.10.734647
MA0077.11.28751
MA0078.11.04495
MA0081.10.714712
MA0083.11.33535
MA0084.11.84562
MA0087.11.29304
MA0088.10.257905
MA0089.10
MA0090.10.751469
MA0091.11.93651
MA0092.10.785956
MA0093.10.642957
MA0095.10
MA0098.10
MA0100.13.60951
MA0101.10.646932
MA0103.10.628063
MA0105.10.846801
MA0106.12.25834
MA0107.10.556367
MA0108.21.15387
MA0109.10
MA0111.10.767139
MA0113.11.00436
MA0114.12.32521
MA0115.11.57693
MA0116.10.560723
MA0117.11.36676
MA0119.10.695578
MA0122.13.08252
MA0124.11.53432
MA0125.11.44766
MA0130.10
MA0131.11.06461
MA0132.10
MA0133.10
MA0135.11.35921
MA0136.10.948776
MA0139.11.12079
MA0140.10.894983
MA0141.10.712476
MA0142.11.12317
MA0143.12.29531
MA0144.10.531867
MA0145.10.273764
MA0146.11.70974
MA0147.10.565108
MA0148.13.29283
MA0149.10.884158
MA0062.21.141
MA0035.20.894194
MA0039.20.195278
MA0138.21.04628
MA0002.20.476938
MA0137.20.666381
MA0104.20.491226
MA0047.23.66129
MA0112.20.264678
MA0065.22.97249
MA0150.10.744617
MA0151.10
MA0152.10.902317
MA0153.11.43021
MA0154.12.30945
MA0155.13.71118
MA0156.10.669101
MA0157.11.09377
MA0158.10
MA0159.11.38935
MA0160.10.871361
MA0161.10
MA0162.10.149099
MA0163.10.122425
MA0164.11.01792
MA0080.20.643061
MA0018.20.987913
MA0099.20.902716
MA0079.20.311277
MA0102.21.88331
MA0258.10.519674
MA0259.10.575594
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
EBF1#187938.9064668465690.00141523283560980.00915317699518531
FOXA1#3169311.08141974938550.000734755275698670.0058129767622675
FOXA2#3170324.63046375266526.68983856509345e-050.00107241757467352
HNF4A#3172323.13229036295378.07584663437677e-050.00122824136689628
SIN3A#2594235.408884726815140.006318961977991520.0276834628138536
SP1#666735.69838137814090.005403962701712170.0246574538251613
USF1#739136.361499277207960.00388404057290560.0190300860102124



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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