FF:11394-118C8: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005363 | ||
| | |DRA_sample_Accession_RNASeq=sRNA-Seq@SAMD00005363 | ||
|accession_numbers=CAGE;DRX008262;DRR009134;DRZ000559;DRZ001944;DRZ011909;DRZ013294 | |||
|accession_numbers_RNASeq=sRNA-Seq;DRX037221;DRR041587;DRZ007229 | |||
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002384,UBERON:0000033,UBERON:0000479,UBERON:0001007,UBERON:0000344,UBERON:0004121,UBERON:0000064,UBERON:0004119,UBERON:0000062,UBERON:0004111,UBERON:0000475,UBERON:0000061,UBERON:0000465,UBERON:0000481,UBERON:0004923,UBERON:0000161,UBERON:0001444,UBERON:0000477,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0003729,UBERON:0010317,UBERON:0001555,UBERON:0001828,UBERON:0001004,UBERON:0000153,UBERON:0007811,UBERON:0000165,UBERON:0000166 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0002320,CL:0002371,CL:0000255,CL:0000057,CL:0002552 | |||
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|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000057,FF:0000001,FF:0000063 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr9:77112244..77112262,+!p1@RORB!2.01!111.80!RORB;;chr1:170632285..170632309,+!p1@PRRX1!1.99!107.67!PRRX1;;chr2:45236540..45236577,-!p1@SIX2!1.86!71.40!SIX2;;chr7:19157248..19157268,-!p1@TWIST1!1.82!172.45!TWIST1;;chr16:86544113..86544145,+!p1@FOXF1!1.75!67.99!FOXF1;;chr6:1389789..1389821,+!p1@FOXF2!1.69!65.72!FOXF2;;chr14:37131058..37131139,+!p1@PAX9!1.64!43.09!PAX9;;chr9:96717629..96717644,-!p1@BARX1!1.59!37.61!BARX1;;chr15:57511609..57511651,+!p2@TCF12!1.57!59.93!TCF12;;chr20:55204351..55204377,+!p1@TFAP2C!1.57!45.88!TFAP2C;;chr1:54204818..54204870,-!p@chr1:54204818..54204870,-!1.51!33.17!GLIS1;;chr9:132427883..132427951,+!p2@PRRX2!1.51!31.00!PRRX2;;chr1:170633348..170633399,+!p2@PRRX1!1.49!40.81!PRRX1;;chr2:239756671..239756732,+!p1@TWIST2!1.48!90.51!TWIST2;;chr9:132427972..132428056,+!p1@PRRX2!1.47!36.58!PRRX2;;chr14:61116183..61116208,-!p1@SIX1!1.43!96.09!SIX1;;chr11:46299199..46299233,+!p1@CREB3L1!1.42!127.30!CREB3L1;;chr6:34204921..34204939,+!p3@HMGA1!1.39!677.09!HMGA1;;chr20:42543441..42543497,+!p1@TOX2!1.38!100.95!TOX2;;chr3:141105705..141105770,+!p4@ZBTB38!1.38!27.79!ZBTB38;;chr14:37126765..37126799,+!p2@PAX9!1.37!22.42!PAX9;;chr15:42749722..42749739,-!p2@ZFP106!1.32!34.92!ZFP106;;chr2:105470562..105470582,+!p@chr2:105470562..105470582,+!1.31!19.22!POU3F3;;chr6:1389989..1390019,+!p2@FOXF2!1.30!18.81!FOXF2;;chr12:115122318..115122331,-!p2@TBX3!1.29!18.70!TBX3;;chr16:86600426..86600441,+!p1@FOXC2!1.24!40.09!FOXC2;;chr7:19157043..19157088,-!p2@TWIST1!1.23!40.19!TWIST1;;chr2:239756739..239756755,+!p2@TWIST2!1.23!26.97!TWIST2;;chr7:44143925..44143970,+!p1@AEBP1!1.22!341.70!AEBP1;;chr2:19558373..19558392,-!p1@OSR1!1.22!42.47!OSR1;;chr19:13134772..13134822,+!p2@NFIX!1.22!22.83!NFIX;;chr3:157823517..157823562,-!p1@SHOX2!1.18!15.09!SHOX2;;chr2:45236579..45236596,-!p2@SIX2!1.18!14.26!SIX2;;chr1:170632250..170632277,+!p7@PRRX1!1.17!13.85!PRRX1;;chr4:4861385..4861398,+!p1@MSX1!1.15!38.54!MSX1;;chr1:170633262..170633285,+!p3@PRRX1!1.15!14.88!PRRX1;;chr11:113930425..113930471,+!p1@ZBTB16!1.13!18.08!ZBTB16;;chr3:12329358..12329393,+!p3@PPARG!1.11!29.14!PPARG;;chr8:49833948..49833973,-!p2@SNAI2!1.08!70.88!SNAI2;;chr3:12329397..12329433,+!p2@PPARG!1.08!25.52!PPARG;;chr8:49833978..49833996,-!p1@SNAI2!1.07!222.15!SNAI2;;chr2:95963052..95963106,+!p1@KCNIP3!1.07!10.75!KCNIP3;;chr2:96012397..96012417,+!p3@KCNIP3!1.07!10.75!KCNIP3;;chr16:86600870..86600921,+!p2@FOXC2!1.07!10.75!FOXC2;;chr6:1389824..1389840,+!p3@FOXF2!1.07!10.64!FOXF2;;chr1:25256756..25256774,-!p1@RUNX3!1.05!19.32!RUNX3;;chr6:85474299..85474324,-!p1@TBX18!1.05!18.50!TBX18;;chr7:14029283..14029311,-!p1@ETV1!1.03!52.90!ETV1;;chr7:44143978..44143989,+!p2@AEBP1!1.03!18.08!AEBP1;;chr7:113726357..113726443,+!p1@FOXP2!1.03!16.84!FOXP2;;chr1:170632137..170632172,+!p10@PRRX1!1.02!9.40!PRRX1;;chr9:77112225..77112238,+!p2@RORB!1.02!9.40!RORB;;chr20:42543506..42543549,+!p2@TOX2!1.01!22.53!TOX2;;chr10:28034739..28034756,-!p1@MKX!1.01!9.20!MKX;;chr11:46299539..46299620,+!p2@CREB3L1!1.00!15.60!CREB3L1;;chr2:96012353..96012378,+!p4@KCNIP3!1.00!8.99!KCNIP3;;chr9:102584262..102584276,+!p1@NR4A3!0.99!19.94!NR4A3;;chrX:106960285..106960299,-!p1@TSC22D3!0.98!236.51!TSC22D3;;chr7:14028488..14028516,-!p2@ETV1!0.98!9.40!ETV1;;chr5:92918919..92918942,+!p1@NR2F1!0.97!37.82!NR2F1;;chr21:47063625..47063658,+!p1@PCBP3!0.97!36.99!PCBP3;;chr9:102584159..102584174,+!p2@NR4A3!0.97!15.40!NR4A3;;chr14:37126814..37126834,+!p4@PAX9!0.96!8.16!PAX9;;chr12:115122303..115122314,-!p6@TBX3!0.96!8.06!TBX3;;chr5:158526917..158526932,-!p1@EBF1!0.95!20.15!EBF1;;chr6:85473156..85473210,-!p2@TBX18!0.95!9.82!TBX18;;chr15:57511589..57511608,+!p4@TCF12!0.95!7.85!TCF12;;chr5:321810..321877,+!p1@AHRR!0.94!25.21!AHRR;;chr14:24837368..24837401,+!p1@NFATC4!0.93!18.39!NFATC4;;chr10:31607702..31607755,+!p3@ZEB1!0.93!8.78!ZEB1;;chr9:94186131..94186174,-!p2@NFIL3!0.92!62.00!NFIL3;;chr1:170632115..170632136,+!p9@PRRX1!0.92!7.34!PRRX1;;chr3:141121847..141121868,+!p5@ZBTB38!0.89!10.64!ZBTB38;;chrY:21906594..21906622,-!p1@KDM5D!0.89!6.72!KDM5D;;chr9:94186101..94186122,-!p1@NFIL3!0.88!96.20!NFIL3;;chr17:59477233..59477263,+!p1@TBX2!0.88!21.39!TBX2;;chr1:75600067..75600094,+!p2@LHX8!0.88!6.61!LHX8;;chr8:93074803..93074845,-!p1@RUNX1T1!0.88!6.51!RUNX1T1;;chr17:7492684..7492778,-!p2@SOX15!0.87!13.95!SOX15;;chr12:115121962..115121987,-!p1@TBX3!0.86!55.28!TBX3;;chrY:2803415..2803468,+!p1@ZFY!0.86!6.30!ZFY;;chr1:170632477..170632506,+!p6@PRRX1!0.86!6.30!PRRX1;;chr2:45236648..45236659,-!p5@SIX2!0.86!6.30!SIX2;;chr7:17338266..17338282,+!p1@AHR!0.85!69.85!AHR;;chr8:72756667..72756736,-!p2@MSC!0.85!9.71!MSC;;chrX:66763856..66763896,+!p1@AR!0.85!8.99!AR;;chr2:96012277..96012290,+!p5@KCNIP3!0.85!6.10!KCNIP3;;chr5:92918956..92918969,+!p4@NR2F1!0.84!6.51!NR2F1;;chr18:52969844..52969895,-!p27@TCF4!0.84!5.89!TCF4;;chr1:158969752..158969780,+!p6@IFI16!0.83!10.44!IFI16;;chr8:72756637..72756664,-!p3@MSC!0.83!6.61!MSC;;chr12:85673977..85674015,+!p1@ALX1!0.83!5.79!ALX1;;chr20:55205825..55205847,+!p2@TFAP2C!0.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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000057;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0002552;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0000161;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0000165;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0000166;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0000344;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0001007;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0001828;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0003729 | |||
|ffid_belonging_in_development=CL:0000134 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 43: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Gingival%252c%2520donor3.CNhs12006.11394-118C8.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Gingival%252c%2520donor3.CNhs12006.11394-118C8.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Gingival%252c%2520donor3.CNhs12006.11394-118C8.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Gingival%252c%2520donor3.CNhs12006.11394-118C8.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Gingival%252c%2520donor3.CNhs12006.11394-118C8.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11394-118C8 | |||
|is_a=EFO:0002091;;FF:0000063 | |||
|is_obsolete= | |||
|library_id=CNhs12006 | |||
|library_id_phase_based=2:CNhs12006 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11394 | |||
|microRNAs_nonnovel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer/#/human#srna;sample;SRhi10013.GTGGCC.11394 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11394 | |||
|microRNAs_novel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer_novel/#/human#srna;sample;SRhi10013.GTGGCC.11394 | |||
|name=Fibroblast - Gingival, donor3 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs12006,LSID837,release011,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=SRhi10013,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,-0.0430542456261666,0,-0.0964828031171254,0.00170997004921005,0,0,0,0.0251091149590056,0,0,0,0,0,0,0,0,0,-0.0360592258882081,0,0.194278018598778,0,0,0,0.019305888192162,0,0,0.076546276962919,0,0,0,0,0,0,0,0,0,0,0,0,-0.0301140796956753,0,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0.180879329076389,0,0.0328780569537375,0.0427037663627782,-0.0154104816957637,0,0,-0.0157617476662555,0,0,0,0,0,0,0,0,0.0427037663627782,0,0,0,0,0.0427037663627782,0,0,0,-0.0653436575037525,0,0,0,0,0,0.0168325314258353,0.0016926769146427,0,0,0.0224617634690782,-0.0743751728708936,-0.057101177930488,0,0.0815818795468414,0.0213518831813891,0,-0.016453471690865,0.0464307363951565,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.20446347053111,0,0,0,-0.0298469850284923,-0.0302128346686865,0,0,0,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0,-0.016453471690865,0,0,0,0.0427037663627782,0.117263784460219,0,0,0,0.0815818795468414,0,0,0.159342011423606,0,-0.356822434291789,-0.100811376160694,0,0,0.335652362670413,0,0,0,0,0,0,0.0427037663627782,0,0,0.328225523208105,0,0.235129462463526,0,0,0,0,-0.0186252810838506,0.296201898008735,0,-0.0838183966113155,-0.0683442610773682,0,0,0,0,-0.0212402168868473,0,-0.120879483793741,-0.0827201683234173,-0.00147197298021562,0.14209573323802,0.094522822369028,0,0,0,0.225903858458453,0.362585342568695,0,0,0.0430800927853031,0.0805427170240355,0,0,0.420280123674232,0,0.397669028982343,0.316263135712832,0,-0.0316362246686495,0,0,0,0,0,0,0,0,0,0,0,0.0762560849837781,-0.0653436575037525,-0.00661526185242895,0,0.0815818795468414,0,0.193443568968939,0,0.0501622319344623,1.10582640345867,0.202127499780665,0.0383314269907439,-0.300625538762319,0.0599492472509696,-0.0407447878346968,0.114708329573144,-0.378458017805537,-0.0880494293299539,0.241154187826417,0.376629021060738,0,0.125977276431768,0.155707309909559,0.0617664587982146,0.0332460487659052,0,0.541468480413872,0.120943237247884,0,0,0.0838100174995281,-0.0912268052079294,0.00987944972748067,0.114326538343504,0.183802267552726,0.0023751072426581,0.180628362394009,0.124364744387183,-0.055999040458405,-0.023643478713707,0.825292167766573,0.406057274537027,0.0134152634814429,0.267645006279195,0,0.180879329076389,0.0376198932683696,0.0213330693671723,-0.0338897828551706,-0.246010298786576,0.0427037663627782,0.226396446200351,0.0818910580728418,0.0621428229548098,0.0290740838385505,0.0200153105285139,0,0.0427037663627782,0.218463630849865,0.0427037663627782,0,0,0.0387756132489804,0.236355965719738,-0.121317645674119,-0.0991281151348402,0.0968643275188092,0,-0.0129301377971985,0,-0.112378143156534,0,-0.0257456974054663,0.242546139740161,0,0.00874769518674734,0,0.0342604589679746,0.51531828003254,0.150696566470731,-0.114202355860976,0.0917884923383848,0.0135341145568876,0.20168205649838,0.266386842127361,0.484571475727535,0.0427037663627782,1.75064901375748,0,0.278890523329779,0.152131322799488,0.0168325314258353,-0.00556067668479265,0.0427037663627782,0.108673421439,0,-0.079314298619268,0.0427037663627782,0.0245413101179314,0.114038949494967,-0.131096925049925,0.25022049463367,0.0184027447325534,6.73483015051213e-05,-0.259665088316549,0.0815818795468414,0.0612692638618466,0.0968097340405969,0,0.378098766122786,0.0923279128941634,0.134381022516416,0.201968974805329,0,0.499850094626441,0,0,0.217528550296008,-0.0852407186141787,0,-0.259312809193181,-0.279483025139042,-0.234400166803191,0.034264245715276,0,0,0.450136919275929,0,0.329719889074354,-0.119282882112568,0.14589802160398,-0.410280457216852,-0.171744461939914,0.0877651718425525,0.318335646717416,0,0,-0.0272924468149656,0,0.165734818223743,0,0,0.323854357910928,0.168913901062708,0,0,0.0427037663627782,-0.0680789474714155,0,0,0,0,0,0,0.0427037663627782,-0.316331059979996,0.0689387042987815,0.0815818795468414,0.0270206575669838,0,0.117263784460219,0,0,0,-0.0111320222993365,0,0.0427037663627782,0.480561242644717,0.0692095846238537,-0.0414355361295788,0.0213518831813891,0,0,0,-0.0654880834032646,-0.0859727776345043,0.0427037663627782,0.0183726126525783,0,0,0,0,-0.0434372234264331,0,0,0.0213518831813891,0,-0.057730457053664,-0.0982092558761239,0,0,0,0.0928614727903131,0,0,0,0.0591661018910436,0.126815140594415,0,0,0.120092150865772,0,0.223999682571548,0,0.00789554159317095,0.189173788095946,0.168138131020461,-0.464963314254901,0,0.0815818795468414,-0.261347131789888,0,0.0471981642428869,0.0705572742332874,0,0,0.1160231531902,0,0,0,0,0,0,0.115405376674598,0.0213518831813891,0,0,0,0,0,0,0.0427037663627782,0,0,0,-0.0689797508848176,-0.010642177111669,0.0427037663627782,0,0,0,0,0,0,0.177296876177626,-0.250690502279891,0,0,0,0,0,0.0427037663627782,0,0,-0.0649050529540717,0,0,0,0,0,-0.0154104816957637,0,0,0,0,-0.0781619394484213,0,0,-0.0964828031171254,0,0,0,0,0,0,0.0158713718923502,0,0,0,0,0,0,-0.123319086035448,-0.303991513569583,0,0.0427037663627782,0,0,0,0,0,-0.0939539691297019,0,0.0815818795468414,0,0,-0.071180607346199,0,0,0,0.0760829442872322,0,-0.0430542456261666,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0213518831813891,0,0,0.0080739085805921,0.687624436908897,0,0.0813297239243884,-0.00248247610965036,0,0,0.079156468309199,0,0,0,0,0,0,0.0734110093423635,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.00593289596833235,0,0,0,0,0,0,0,0.019305888192162,0,0,0.141714306078697,0,0,0,0,0.0316665376080631,0,0.0711611224792455,0.264444159251856,0.0971397237591176,0,0,0,0.088385434543965,0.180879329076389,0.012290576814364,0.0427037663627782,0.0427037663627782,0.262942501655453,0,0,0,0,0,0,0,0,0.0427037663627782,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0360592258882081,0,0,0,0,0,0,0,0,0,0,0,0,0.0213518831813891,0,0,0,0,0,0,0,0,0,0,0,0,0.0427037663627782,0,0,0,0,0,0,0,0,0.0427037663627782,0.0246205289546932,0.0815818795468414,0,0,0,0,0,0,0.0427037663627782,0,0,0,0,0.0213518831813891,0,0,0,0,0,0,0,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| |||
|rna_box=118 | |||
|rna_catalog_number=SC2625 | |||
|rna_concentration=0.669 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-isopropanol-v1.0 | |||
|rna_lot_number=427 | |||
|rna_od260/230= | |||
|rna_od260/280= | |||
|rna_position=C8 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=118C8 | |||
|rna_weight_ug=10 | |||
|rnaseq_library_id=SRhi10013.GTGGCC | |||
|sample_age=fetal | |||
|sample_category=primary cells | |||
|sample_cell_catalog=N/A | |||
|sample_cell_line= | |||
|sample_cell_lot=N/A | |||
|sample_cell_type=fibroblast | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=Sciencell/3H | |||
|sample_description= | |||
|sample_dev_stage=fetus | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.41513297893593e-233!GO:0005737;cytoplasm;1.83436919597171e-186!GO:0043226;organelle;2.54561700335631e-180!GO:0043229;intracellular organelle;4.42189536888593e-180!GO:0043231;intracellular membrane-bound organelle;4.42189536888593e-180!GO:0043227;membrane-bound organelle;9.71445981916883e-180!GO:0044444;cytoplasmic part;4.24246914888814e-131!GO:0044422;organelle part;3.14847969229758e-119!GO:0044446;intracellular organelle part;6.94080071780029e-118!GO:0044238;primary metabolic process;8.06972887288347e-89!GO:0044237;cellular metabolic process;1.77248289835469e-88!GO:0043170;macromolecule metabolic process;2.92399254036165e-78!GO:0032991;macromolecular complex;4.39877018316715e-76!GO:0005515;protein binding;1.45408306517197e-73!GO:0030529;ribonucleoprotein complex;2.08917148977756e-72!GO:0005634;nucleus;6.08502634738814e-70!GO:0043233;organelle lumen;6.75678140739484e-65!GO:0031974;membrane-enclosed lumen;6.75678140739484e-65!GO:0003723;RNA binding;2.31471045180883e-63!GO:0044428;nuclear part;3.06680762519992e-61!GO:0005739;mitochondrion;6.36336893999743e-60!GO:0031090;organelle membrane;1.72451530398031e-48!GO:0019538;protein metabolic process;8.73353180458595e-48!GO:0016043;cellular component organization and biogenesis;7.33323747869444e-45!GO:0043283;biopolymer metabolic process;8.0129303819065e-45!GO:0005840;ribosome;8.0129303819065e-45!GO:0006412;translation;5.2708971667966e-44!GO:0044260;cellular macromolecule metabolic process;2.96422489856132e-43!GO:0010467;gene expression;9.8915131532253e-43!GO:0044267;cellular protein metabolic process;3.55301347067659e-42!GO:0015031;protein transport;3.05204446524355e-41!GO:0033036;macromolecule localization;3.35811885539885e-41!GO:0006396;RNA processing;6.4631932968503e-40!GO:0009058;biosynthetic process;6.48223135522189e-40!GO:0044429;mitochondrial part;1.19037895652217e-39!GO:0005829;cytosol;3.78032003460757e-39!GO:0003735;structural constituent of ribosome;1.24812552371929e-38!GO:0031981;nuclear lumen;2.1397341421565e-38!GO:0045184;establishment of protein localization;3.01592704417001e-38!GO:0008104;protein localization;5.80671268923869e-38!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.26629281304997e-37!GO:0043234;protein complex;7.50174122147408e-37!GO:0044249;cellular biosynthetic process;2.21050934610608e-36!GO:0031967;organelle envelope;1.64747520916115e-35!GO:0009059;macromolecule biosynthetic process;2.28979343583529e-35!GO:0031975;envelope;2.82801475774655e-35!GO:0016071;mRNA metabolic process;1.2775372367118e-34!GO:0033279;ribosomal subunit;4.34581912381324e-34!GO:0008380;RNA splicing;2.19523850423571e-31!GO:0046907;intracellular transport;1.0185297845326e-30!GO:0006397;mRNA processing;7.36458607899726e-28!GO:0065003;macromolecular complex assembly;1.26354608545561e-27!GO:0006886;intracellular protein transport;7.68718603488951e-27!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.37643807309272e-26!GO:0005740;mitochondrial envelope;9.11193375236556e-26!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.05333302388112e-25!GO:0005654;nucleoplasm;6.94013777321205e-25!GO:0031966;mitochondrial membrane;2.03605644125364e-24!GO:0022607;cellular component assembly;2.20497230802402e-24!GO:0006996;organelle organization and biogenesis;2.42248672231155e-24!GO:0003676;nucleic acid binding;3.22634383860256e-24!GO:0019866;organelle inner membrane;7.9190964640344e-23!GO:0043228;non-membrane-bound organelle;1.87978279540811e-22!GO:0043232;intracellular non-membrane-bound organelle;1.87978279540811e-22!GO:0000166;nucleotide binding;1.60286252764531e-21!GO:0005743;mitochondrial inner membrane;2.44458146443697e-21!GO:0044451;nucleoplasm part;7.9821723730001e-21!GO:0016070;RNA metabolic process;1.0734577854793e-20!GO:0005681;spliceosome;1.35346300550026e-20!GO:0044445;cytosolic part;1.93443381473465e-20!GO:0008134;transcription factor binding;4.61053227689265e-20!GO:0051641;cellular localization;5.64210789210842e-20!GO:0051649;establishment of cellular localization;6.24139002923371e-20!GO:0012505;endomembrane system;8.19829691850934e-20!GO:0006457;protein folding;4.8568018737506e-19!GO:0006119;oxidative phosphorylation;5.85402761239797e-19!GO:0048770;pigment granule;1.53762282174702e-18!GO:0042470;melanosome;1.53762282174702e-18!GO:0005783;endoplasmic reticulum;2.27415356519248e-18!GO:0015935;small ribosomal subunit;3.92167822594212e-18!GO:0022618;protein-RNA complex assembly;1.70013651286405e-17!GO:0031980;mitochondrial lumen;2.02724962684784e-17!GO:0005759;mitochondrial matrix;2.02724962684784e-17!GO:0006512;ubiquitin cycle;2.64528741470408e-17!GO:0016874;ligase activity;2.68248607689617e-17!GO:0006259;DNA metabolic process;2.76747231127616e-17!GO:0005794;Golgi apparatus;3.46434797462613e-17!GO:0015934;large ribosomal subunit;5.53969466139204e-17!GO:0016462;pyrophosphatase activity;1.04646110292109e-16!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.23253604643746e-16!GO:0016817;hydrolase activity, acting on acid anhydrides;1.81540342384886e-16!GO:0051186;cofactor metabolic process;2.44616429448519e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;4.69764933331114e-16!GO:0017111;nucleoside-triphosphatase activity;5.53998342769858e-16!GO:0043285;biopolymer catabolic process;5.82154455435038e-16!GO:0044455;mitochondrial membrane part;5.83517502788855e-16!GO:0044265;cellular macromolecule catabolic process;8.18065603624027e-16!GO:0006511;ubiquitin-dependent protein catabolic process;9.32098615755473e-16!GO:0019941;modification-dependent protein catabolic process;9.49227874553954e-16!GO:0043632;modification-dependent macromolecule catabolic process;9.49227874553954e-16!GO:0044257;cellular protein catabolic process;1.35893698811769e-15!GO:0008135;translation factor activity, nucleic acid binding;1.76599132146339e-15!GO:0044432;endoplasmic reticulum part;4.27147905501393e-15!GO:0017076;purine nucleotide binding;4.36052334398642e-15!GO:0032553;ribonucleotide binding;2.42075929136964e-14!GO:0032555;purine ribonucleotide binding;2.42075929136964e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.93482116000928e-14!GO:0007049;cell cycle;3.15765728026859e-14!GO:0048193;Golgi vesicle transport;3.9256735520556e-14!GO:0030163;protein catabolic process;4.00124802200468e-14!GO:0006605;protein targeting;4.1086880917156e-14!GO:0005730;nucleolus;4.1086880917156e-14!GO:0009057;macromolecule catabolic process;4.1086880917156e-14!GO:0005746;mitochondrial respiratory chain;4.75979450154578e-14!GO:0044248;cellular catabolic process;5.36831738277114e-14!GO:0000502;proteasome complex (sensu Eukaryota);6.89818579204677e-14!GO:0016192;vesicle-mediated transport;9.42616674568402e-14!GO:0043412;biopolymer modification;1.2113748325022e-13!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.60924153607652e-13!GO:0003712;transcription cofactor activity;7.33702539830198e-13!GO:0006732;coenzyme metabolic process;1.20398660253889e-12!GO:0050794;regulation of cellular process;1.38714210505252e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.4117611278353e-12!GO:0005793;ER-Golgi intermediate compartment;2.23901670998366e-12!GO:0003743;translation initiation factor activity;2.83831028548292e-12!GO:0006366;transcription from RNA polymerase II promoter;2.99298412963107e-12!GO:0050136;NADH dehydrogenase (quinone) activity;3.05515662952893e-12!GO:0003954;NADH dehydrogenase activity;3.05515662952893e-12!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.05515662952893e-12!GO:0006464;protein modification process;3.14789456920528e-12!GO:0051082;unfolded protein binding;3.73271979506622e-12!GO:0012501;programmed cell death;5.85087134928081e-12!GO:0005761;mitochondrial ribosome;6.1763981604433e-12!GO:0000313;organellar ribosome;6.1763981604433e-12!GO:0048523;negative regulation of cellular process;7.00300566185604e-12!GO:0006413;translational initiation;1.10794759398692e-11!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.24852975392959e-11!GO:0006915;apoptosis;1.29560059376219e-11!GO:0030554;adenyl nucleotide binding;4.25373177623415e-11!GO:0000398;nuclear mRNA splicing, via spliceosome;5.04009315515828e-11!GO:0000375;RNA splicing, via transesterification reactions;5.04009315515828e-11!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;5.04009315515828e-11!GO:0008219;cell death;6.00276861528735e-11!GO:0016265;death;6.00276861528735e-11!GO:0042775;organelle ATP synthesis coupled electron transport;8.3498829142146e-11!GO:0042773;ATP synthesis coupled electron transport;8.3498829142146e-11!GO:0005524;ATP binding;1.01763515364679e-10!GO:0006446;regulation of translational initiation;1.08542157073291e-10!GO:0043687;post-translational protein modification;1.15204313236523e-10!GO:0005635;nuclear envelope;1.15321740691802e-10!GO:0016604;nuclear body;1.24444240407257e-10!GO:0022402;cell cycle process;1.47327910181558e-10!GO:0030964;NADH dehydrogenase complex (quinone);1.47327910181558e-10!GO:0045271;respiratory chain complex I;1.47327910181558e-10!GO:0005747;mitochondrial respiratory chain complex I;1.47327910181558e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.54231390727457e-10!GO:0032559;adenyl ribonucleotide binding;1.54941281965194e-10!GO:0009055;electron carrier activity;1.76803511259273e-10!GO:0006974;response to DNA damage stimulus;2.46580013626771e-10!GO:0005789;endoplasmic reticulum membrane;3.18097976155774e-10!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;3.38145081521859e-10!GO:0031965;nuclear membrane;4.03524172494385e-10!GO:0006913;nucleocytoplasmic transport;6.03599948368568e-10!GO:0048519;negative regulation of biological process;6.94245205168339e-10!GO:0008639;small protein conjugating enzyme activity;1.1313146202561e-09!GO:0051169;nuclear transport;1.27698829936979e-09!GO:0050789;regulation of biological process;1.65301207105276e-09!GO:0004842;ubiquitin-protein ligase activity;2.48988092820342e-09!GO:0042254;ribosome biogenesis and assembly;2.9873271645481e-09!GO:0019787;small conjugating protein ligase activity;3.10680807673202e-09!GO:0005768;endosome;3.94196153617399e-09!GO:0006163;purine nucleotide metabolic process;4.70372760448001e-09!GO:0008565;protein transporter activity;5.5708210988453e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;5.58256844960704e-09!GO:0009259;ribonucleotide metabolic process;7.49775195183913e-09!GO:0016607;nuclear speck;7.49775195183913e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;7.89336115068529e-09!GO:0006461;protein complex assembly;9.8085895622325e-09!GO:0009150;purine ribonucleotide metabolic process;1.18701377048039e-08!GO:0016491;oxidoreductase activity;1.24276568385734e-08!GO:0044453;nuclear membrane part;1.62122452331185e-08!GO:0009056;catabolic process;1.64592342389686e-08!GO:0045333;cellular respiration;2.19097236625509e-08!GO:0017038;protein import;2.20148048784809e-08!GO:0051246;regulation of protein metabolic process;2.30698611538227e-08!GO:0051188;cofactor biosynthetic process;2.33677680003021e-08!GO:0003924;GTPase activity;2.37738858924198e-08!GO:0051726;regulation of cell cycle;2.9239671984831e-08!GO:0006164;purine nucleotide biosynthetic process;3.27498605301336e-08!GO:0000074;regulation of progression through cell cycle;3.37248742265825e-08!GO:0009060;aerobic respiration;3.69980500755539e-08!GO:0051276;chromosome organization and biogenesis;3.7908800857327e-08!GO:0044431;Golgi apparatus part;4.05630290205909e-08!GO:0016881;acid-amino acid ligase activity;4.59673170175514e-08!GO:0009199;ribonucleoside triphosphate metabolic process;4.78746822942308e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;5.33583658942559e-08!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;5.33583658942559e-08!GO:0004812;aminoacyl-tRNA ligase activity;5.33583658942559e-08!GO:0016875;ligase activity, forming carbon-oxygen bonds;5.33583658942559e-08!GO:0006325;establishment and/or maintenance of chromatin architecture;5.4294662660715e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;5.92275387909263e-08!GO:0009144;purine nucleoside triphosphate metabolic process;5.92275387909263e-08!GO:0006399;tRNA metabolic process;6.50318750261451e-08!GO:0016564;transcription repressor activity;7.00077915369284e-08!GO:0006888;ER to Golgi vesicle-mediated transport;7.80282087701719e-08!GO:0009152;purine ribonucleotide biosynthetic process;7.95591592797783e-08!GO:0006281;DNA repair;8.77784033212291e-08!GO:0000278;mitotic cell cycle;1.0012711872366e-07!GO:0043038;amino acid activation;1.02544995927259e-07!GO:0006418;tRNA aminoacylation for protein translation;1.02544995927259e-07!GO:0043039;tRNA aminoacylation;1.02544995927259e-07!GO:0009141;nucleoside triphosphate metabolic process;1.09228756268102e-07!GO:0030120;vesicle coat;1.09320655830512e-07!GO:0030662;coated vesicle membrane;1.09320655830512e-07!GO:0009260;ribonucleotide biosynthetic process;1.25561686187009e-07!GO:0009719;response to endogenous stimulus;1.26705685007933e-07!GO:0015986;ATP synthesis coupled proton transport;1.67255435973516e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.67255435973516e-07!GO:0019829;cation-transporting ATPase activity;1.67341765088166e-07!GO:0006323;DNA packaging;1.83753506849908e-07!GO:0048475;coated membrane;1.89988730008754e-07!GO:0030117;membrane coat;1.89988730008754e-07!GO:0004386;helicase activity;2.03478896291844e-07!GO:0046034;ATP metabolic process;2.06678487486845e-07!GO:0006916;anti-apoptosis;2.28492954465503e-07!GO:0042623;ATPase activity, coupled;2.32784029172291e-07!GO:0019222;regulation of metabolic process;2.78991778202535e-07!GO:0016887;ATPase activity;3.19755397378449e-07!GO:0044440;endosomal part;3.2109252308475e-07!GO:0010008;endosome membrane;3.2109252308475e-07!GO:0003713;transcription coactivator activity;3.55455208932659e-07!GO:0005788;endoplasmic reticulum lumen;3.87169138972777e-07!GO:0015078;hydrogen ion transmembrane transporter activity;4.3751399296335e-07!GO:0031324;negative regulation of cellular metabolic process;4.90542810604016e-07!GO:0043566;structure-specific DNA binding;4.95183891783781e-07!GO:0009142;nucleoside triphosphate biosynthetic process;5.82678805650094e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;5.82678805650094e-07!GO:0045786;negative regulation of progression through cell cycle;6.06273259695868e-07!GO:0051187;cofactor catabolic process;6.17141812400593e-07!GO:0005525;GTP binding;6.2479031985956e-07!GO:0043069;negative regulation of programmed cell death;6.58876008847842e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;6.67726071110365e-07!GO:0042981;regulation of apoptosis;6.80051880587396e-07!GO:0006099;tricarboxylic acid cycle;7.03481962669271e-07!GO:0046356;acetyl-CoA catabolic process;7.03481962669271e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;7.07935848769319e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;7.11807952236179e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;7.11807952236179e-07!GO:0006091;generation of precursor metabolites and energy;7.62651203955423e-07!GO:0043066;negative regulation of apoptosis;7.79297475183467e-07!GO:0043067;regulation of programmed cell death;8.27895662728728e-07!GO:0005643;nuclear pore;9.85392476767047e-07!GO:0008026;ATP-dependent helicase activity;1.03129016488609e-06!GO:0009109;coenzyme catabolic process;1.11087495894379e-06!GO:0009108;coenzyme biosynthetic process;1.26219320184271e-06!GO:0016563;transcription activator activity;1.30184405802094e-06!GO:0015980;energy derivation by oxidation of organic compounds;1.30395030326279e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.31490908082994e-06!GO:0005773;vacuole;1.42607052129437e-06!GO:0005667;transcription factor complex;1.70514826446578e-06!GO:0003714;transcription corepressor activity;1.91724147838261e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;1.94599117575086e-06!GO:0031988;membrane-bound vesicle;2.07375613681795e-06!GO:0016023;cytoplasmic membrane-bound vesicle;2.25387097621849e-06!GO:0006084;acetyl-CoA metabolic process;2.27896564347744e-06!GO:0051170;nuclear import;2.32075195758963e-06!GO:0006754;ATP biosynthetic process;2.35691798996365e-06!GO:0006753;nucleoside phosphate metabolic process;2.35691798996365e-06!GO:0000139;Golgi membrane;2.91228999039374e-06!GO:0000151;ubiquitin ligase complex;2.92862257178939e-06!GO:0016469;proton-transporting two-sector ATPase complex;2.92862257178939e-06!GO:0006793;phosphorus metabolic process;2.96159311319178e-06!GO:0006796;phosphate metabolic process;2.96159311319178e-06!GO:0032446;protein modification by small protein conjugation;3.18172544922933e-06!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;3.31332011060387e-06!GO:0050657;nucleic acid transport;3.42187035784725e-06!GO:0051236;establishment of RNA localization;3.42187035784725e-06!GO:0050658;RNA transport;3.42187035784725e-06!GO:0031982;vesicle;3.66184266499815e-06!GO:0006606;protein import into nucleus;3.6626437391004e-06!GO:0003697;single-stranded DNA binding;3.97142502742774e-06!GO:0009892;negative regulation of metabolic process;4.02469326416807e-06!GO:0031410;cytoplasmic vesicle;4.21359475318884e-06!GO:0016567;protein ubiquitination;4.239346172842e-06!GO:0006403;RNA localization;4.44286562896076e-06!GO:0005694;chromosome;5.43030319726712e-06!GO:0065002;intracellular protein transport across a membrane;5.64467267611373e-06!GO:0065007;biological regulation;6.0900301708657e-06!GO:0032561;guanyl ribonucleotide binding;6.43057047687464e-06!GO:0019001;guanyl nucleotide binding;6.43057047687464e-06!GO:0031252;leading edge;6.6601539501275e-06!GO:0005839;proteasome core complex (sensu Eukaryota);6.73297880253727e-06!GO:0000323;lytic vacuole;6.80874689498815e-06!GO:0005764;lysosome;6.80874689498815e-06!GO:0016481;negative regulation of transcription;7.20837896681869e-06!GO:0045259;proton-transporting ATP synthase complex;7.65886924164104e-06!GO:0005770;late endosome;7.66476793969713e-06!GO:0030532;small nuclear ribonucleoprotein complex;7.93043764785933e-06!GO:0008654;phospholipid biosynthetic process;7.9484679838235e-06!GO:0016568;chromatin modification;8.57085122828232e-06!GO:0005798;Golgi-associated vesicle;9.58942786089095e-06!GO:0000245;spliceosome assembly;9.71079989325478e-06!GO:0046930;pore complex;9.86764581123237e-06!GO:0016853;isomerase activity;1.00475952813255e-05!GO:0006364;rRNA processing;1.08827161068825e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.14884676400798e-05!GO:0015630;microtubule cytoskeleton;1.23982218829656e-05!GO:0009117;nucleotide metabolic process;1.2409385361559e-05!GO:0065004;protein-DNA complex assembly;1.26608596950978e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;1.29911913931485e-05!GO:0006613;cotranslational protein targeting to membrane;1.36264458838313e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;1.63953804965756e-05!GO:0016740;transferase activity;1.68605754455938e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.9432217964372e-05!GO:0007005;mitochondrion organization and biogenesis;2.0012658616607e-05!GO:0016072;rRNA metabolic process;2.01274907612421e-05!GO:0016859;cis-trans isomerase activity;2.06800975328075e-05!GO:0006752;group transfer coenzyme metabolic process;2.56564788773981e-05!GO:0030133;transport vesicle;2.61083541335358e-05!GO:0016310;phosphorylation;3.09566077643607e-05!GO:0005813;centrosome;3.48329561995136e-05!GO:0008361;regulation of cell size;3.48329561995136e-05!GO:0022403;cell cycle phase;3.92623663108995e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;3.92674314543057e-05!GO:0019867;outer membrane;4.01047154919185e-05!GO:0045454;cell redox homeostasis;4.01264538744072e-05!GO:0019899;enzyme binding;4.40128783760618e-05!GO:0030036;actin cytoskeleton organization and biogenesis;4.51760460309494e-05!GO:0016049;cell growth;4.9257720396317e-05!GO:0004298;threonine endopeptidase activity;5.10608238770418e-05!GO:0031968;organelle outer membrane;5.28187840625043e-05!GO:0006260;DNA replication;5.32679091506008e-05!GO:0051427;hormone receptor binding;5.63680416696179e-05!GO:0030867;rough endoplasmic reticulum membrane;6.54194939961074e-05!GO:0007243;protein kinase cascade;6.54424251139804e-05!GO:0051028;mRNA transport;6.95483861581459e-05!GO:0031323;regulation of cellular metabolic process;7.54187196059345e-05!GO:0016787;hydrolase activity;7.91975750180012e-05!GO:0019843;rRNA binding;8.57988734714691e-05!GO:0051301;cell division;8.62648563884518e-05!GO:0005769;early endosome;8.82648945280299e-05!GO:0005762;mitochondrial large ribosomal subunit;8.82648945280299e-05!GO:0000315;organellar large ribosomal subunit;8.82648945280299e-05!GO:0016126;sterol biosynthetic process;8.90986562868391e-05!GO:0006333;chromatin assembly or disassembly;9.42442879456846e-05!GO:0000087;M phase of mitotic cell cycle;9.59782127974583e-05!GO:0003724;RNA helicase activity;0.000101417425620518!GO:0044427;chromosomal part;0.000104319893672546!GO:0048522;positive regulation of cellular process;0.000104330298315068!GO:0005815;microtubule organizing center;0.000117816552487468!GO:0035257;nuclear hormone receptor binding;0.000118190913919009!GO:0043021;ribonucleoprotein binding;0.000124918763995178!GO:0005905;coated pit;0.000126541128512642!GO:0051789;response to protein stimulus;0.000127391497264593!GO:0006986;response to unfolded protein;0.000127391497264593!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.000130149128731!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;0.000135573292605834!GO:0007067;mitosis;0.000135573292605834!GO:0005741;mitochondrial outer membrane;0.000156386553726476!GO:0005048;signal sequence binding;0.000156386553726476!GO:0007264;small GTPase mediated signal transduction;0.000180428423856552!GO:0006350;transcription;0.000205147392360239!GO:0043623;cellular protein complex assembly;0.000229899267109194!GO:0001558;regulation of cell growth;0.000234406322829594!GO:0005791;rough endoplasmic reticulum;0.000239541063720673!GO:0045893;positive regulation of transcription, DNA-dependent;0.000239681999743409!GO:0008610;lipid biosynthetic process;0.000247386243527019!GO:0050662;coenzyme binding;0.000270663159390912!GO:0016779;nucleotidyltransferase activity;0.000307468768250331!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.000325596084900773!GO:0006612;protein targeting to membrane;0.000331289428566983!GO:0033116;ER-Golgi intermediate compartment membrane;0.000357414345152361!GO:0045941;positive regulation of transcription;0.000364312502139328!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000399010646853995!GO:0000785;chromatin;0.000407732120039602!GO:0019752;carboxylic acid metabolic process;0.000410648085420882!GO:0046474;glycerophospholipid biosynthetic process;0.000440041305452271!GO:0030029;actin filament-based process;0.0004493496608836!GO:0006082;organic acid metabolic process;0.000486830451086911!GO:0005885;Arp2/3 protein complex;0.000524922073497896!GO:0010468;regulation of gene expression;0.00057414127311633!GO:0006402;mRNA catabolic process;0.000600683821025864!GO:0030663;COPI coated vesicle membrane;0.000647231002715066!GO:0030126;COPI vesicle coat;0.000647231002715066!GO:0016044;membrane organization and biogenesis;0.000647231002715066!GO:0003729;mRNA binding;0.000647231002715066!GO:0008250;oligosaccharyl transferase complex;0.000711885617425484!GO:0045892;negative regulation of transcription, DNA-dependent;0.000730264293089371!GO:0006695;cholesterol biosynthetic process;0.000766365686269112!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000834143609676718!GO:0003690;double-stranded DNA binding;0.000848264000044389!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000875539865248853!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000908466796204274!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000993374962396307!GO:0008092;cytoskeletal protein binding;0.00100718186630474!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00106417809647234!GO:0004576;oligosaccharyl transferase activity;0.00106862744912632!GO:0043488;regulation of mRNA stability;0.00106862744912632!GO:0043487;regulation of RNA stability;0.00106862744912632!GO:0007050;cell cycle arrest;0.00108399933135819!GO:0051287;NAD binding;0.0010925265202089!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.0010925265202089!GO:0004177;aminopeptidase activity;0.00110516553909715!GO:0007010;cytoskeleton organization and biogenesis;0.00110865124715887!GO:0000314;organellar small ribosomal subunit;0.00110958090119897!GO:0005763;mitochondrial small ribosomal subunit;0.00110958090119897!GO:0051329;interphase of mitotic cell cycle;0.0011482611643382!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00116387840946112!GO:0051920;peroxiredoxin activity;0.00118626985722067!GO:0048037;cofactor binding;0.00119709347296413!GO:0030132;clathrin coat of coated pit;0.00121225553713667!GO:0006414;translational elongation;0.00124476651150269!GO:0030137;COPI-coated vesicle;0.00137645971159269!GO:0006891;intra-Golgi vesicle-mediated transport;0.00139011364593105!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00139011364593105!GO:0051252;regulation of RNA metabolic process;0.00141181775203919!GO:0046467;membrane lipid biosynthetic process;0.00144155416798617!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00158023778736723!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00158023778736723!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00158023778736723!GO:0005096;GTPase activator activity;0.00163152143460567!GO:0042802;identical protein binding;0.00163152143460567!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00163179156794786!GO:0016363;nuclear matrix;0.00173965209545759!GO:0008186;RNA-dependent ATPase activity;0.00209706642772878!GO:0030521;androgen receptor signaling pathway;0.00212660936309978!GO:0008047;enzyme activator activity;0.00217334973370962!GO:0045045;secretory pathway;0.00228998287496687!GO:0008154;actin polymerization and/or depolymerization;0.00229125984368426!GO:0048471;perinuclear region of cytoplasm;0.00232839557277537!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.00234149855025918!GO:0044262;cellular carbohydrate metabolic process;0.0023988881229955!GO:0009165;nucleotide biosynthetic process;0.0023988881229955!GO:0035258;steroid hormone receptor binding;0.00247590637611349!GO:0043284;biopolymer biosynthetic process;0.00251331364509537!GO:0018196;peptidyl-asparagine modification;0.00251331364509537!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00251331364509537!GO:0031072;heat shock protein binding;0.00257673048193916!GO:0006979;response to oxidative stress;0.00259163954883073!GO:0000279;M phase;0.00259327552505534!GO:0030027;lamellipodium;0.00271074299210204!GO:0009967;positive regulation of signal transduction;0.00289718000415918!GO:0048500;signal recognition particle;0.00291360425767797!GO:0051325;interphase;0.00322193794152638!GO:0000059;protein import into nucleus, docking;0.00326988479908573!GO:0048468;cell development;0.00333767662685589!GO:0051168;nuclear export;0.00346240773992025!GO:0051128;regulation of cellular component organization and biogenesis;0.00358152945623426!GO:0003899;DNA-directed RNA polymerase activity;0.00365599821546836!GO:0030118;clathrin coat;0.00366486951359274!GO:0048518;positive regulation of biological process;0.0037569563749905!GO:0030134;ER to Golgi transport vesicle;0.00385342649732974!GO:0065009;regulation of a molecular function;0.00390923972987495!GO:0008139;nuclear localization sequence binding;0.00395273716857106!GO:0017166;vinculin binding;0.00397033159876282!GO:0046914;transition metal ion binding;0.00402459762934233!GO:0006650;glycerophospholipid metabolic process;0.00415501083897245!GO:0046489;phosphoinositide biosynthetic process;0.00415501083897245!GO:0005100;Rho GTPase activator activity;0.00423492492651593!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00423492492651593!GO:0006352;transcription initiation;0.0045957617286256!GO:0003702;RNA polymerase II transcription factor activity;0.00463014835496072!GO:0004674;protein serine/threonine kinase activity;0.00471889702777183!GO:0006401;RNA catabolic process;0.00475837702599654!GO:0030127;COPII vesicle coat;0.00479817363244364!GO:0012507;ER to Golgi transport vesicle membrane;0.00479817363244364!GO:0040008;regulation of growth;0.004941521869143!GO:0030658;transport vesicle membrane;0.00513254944068219!GO:0033673;negative regulation of kinase activity;0.00513970698632092!GO:0006469;negative regulation of protein kinase activity;0.00513970698632092!GO:0030518;steroid hormone receptor signaling pathway;0.00518348526645937!GO:0030041;actin filament polymerization;0.00522019650989537!GO:0006334;nucleosome assembly;0.00532410900131621!GO:0004004;ATP-dependent RNA helicase activity;0.00545360339086717!GO:0032774;RNA biosynthetic process;0.00572864627251566!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.005805694449546!GO:0045047;protein targeting to ER;0.005805694449546!GO:0031901;early endosome membrane;0.00594943165834659!GO:0006351;transcription, DNA-dependent;0.00595351636349573!GO:0000049;tRNA binding;0.00627348685107024!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.00637502528312088!GO:0015399;primary active transmembrane transporter activity;0.00637502528312088!GO:0008286;insulin receptor signaling pathway;0.0063801001116638!GO:0043681;protein import into mitochondrion;0.00649723028799347!GO:0051540;metal cluster binding;0.00649723028799347!GO:0051536;iron-sulfur cluster binding;0.00649723028799347!GO:0031902;late endosome membrane;0.00663457187333643!GO:0006383;transcription from RNA polymerase III promoter;0.006730020923674!GO:0016197;endosome transport;0.00706532900407598!GO:0031625;ubiquitin protein ligase binding;0.00706532900407598!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00727832146292892!GO:0015992;proton transport;0.00737415371994121!GO:0006818;hydrogen transport;0.00742579677502506!GO:0048487;beta-tubulin binding;0.00742579677502506!GO:0051348;negative regulation of transferase activity;0.00745799245858021!GO:0006289;nucleotide-excision repair;0.00757106302623528!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0077369657710021!GO:0030880;RNA polymerase complex;0.00774759081078009!GO:0022890;inorganic cation transmembrane transporter activity;0.00783114266113694!GO:0045449;regulation of transcription;0.00785501392737712!GO:0031497;chromatin assembly;0.0080872045146156!GO:0008312;7S RNA binding;0.00809992489717833!GO:0001726;ruffle;0.00815669100796899!GO:0016408;C-acyltransferase activity;0.00831845178718799!GO:0003682;chromatin binding;0.00838275494813458!GO:0008180;signalosome;0.00844251552452118!GO:0016251;general RNA polymerase II transcription factor activity;0.00844492723775111!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00893721081468945!GO:0006892;post-Golgi vesicle-mediated transport;0.00920092313135942!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00930261493658806!GO:0006118;electron transport;0.00934264037125409!GO:0030119;AP-type membrane coat adaptor complex;0.00953160608168103!GO:0003746;translation elongation factor activity;0.00956473074882227!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00973570007757604!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00973570007757604!GO:0005819;spindle;0.00999847885750143!GO:0046483;heterocycle metabolic process;0.00999847885750143!GO:0005869;dynactin complex;0.0106041573476759!GO:0005774;vacuolar membrane;0.0107769113559649!GO:0007006;mitochondrial membrane organization and biogenesis;0.0109652009325674!GO:0006509;membrane protein ectodomain proteolysis;0.0111735703343533!GO:0033619;membrane protein proteolysis;0.0111735703343533!GO:0050681;androgen receptor binding;0.0112281039840031!GO:0006740;NADPH regeneration;0.0113087923523568!GO:0006098;pentose-phosphate shunt;0.0113087923523568!GO:0006607;NLS-bearing substrate import into nucleus;0.0116724931230263!GO:0015631;tubulin binding;0.0117709505629977!GO:0006520;amino acid metabolic process;0.011859575525427!GO:0032984;macromolecular complex disassembly;0.0118703535372189!GO:0051539;4 iron, 4 sulfur cluster binding;0.0118703535372189!GO:0006595;polyamine metabolic process;0.0118703535372189!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0121530577249601!GO:0015002;heme-copper terminal oxidase activity;0.0121530577249601!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0121530577249601!GO:0004129;cytochrome-c oxidase activity;0.0121530577249601!GO:0000209;protein polyubiquitination;0.0128612238486186!GO:0006778;porphyrin metabolic process;0.0133897100435312!GO:0033013;tetrapyrrole metabolic process;0.0133897100435312!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0134798394278053!GO:0000428;DNA-directed RNA polymerase complex;0.0134798394278053!GO:0043022;ribosome binding;0.0137698957437414!GO:0030176;integral to endoplasmic reticulum membrane;0.0139543060075142!GO:0030660;Golgi-associated vesicle membrane;0.0140029835374498!GO:0005099;Ras GTPase activator activity;0.0142020833751861!GO:0017015;regulation of transforming growth factor beta receptor signaling pathway;0.0147272710199176!GO:0005669;transcription factor TFIID complex;0.0149765693370126!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.0149765693370126!GO:0006984;ER-nuclear signaling pathway;0.0152850028458087!GO:0051493;regulation of cytoskeleton organization and biogenesis;0.0153666162507996!GO:0033043;regulation of organelle organization and biogenesis;0.0153666162507996!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0159673462099641!GO:0000339;RNA cap binding;0.0160998730334108!GO:0007034;vacuolar transport;0.0162268074161135!GO:0030131;clathrin adaptor complex;0.016488240785076!GO:0000096;sulfur amino acid metabolic process;0.0166004185435651!GO:0022408;negative regulation of cell-cell adhesion;0.0168436597230361!GO:0035035;histone acetyltransferase binding;0.0169144521780595!GO:0051101;regulation of DNA binding;0.0170257710541116!GO:0003711;transcription elongation regulator activity;0.0173012393531613!GO:0006497;protein amino acid lipidation;0.0178016792200195!GO:0033559;unsaturated fatty acid metabolic process;0.0179485155489494!GO:0006636;unsaturated fatty acid biosynthetic process;0.0179485155489494!GO:0006693;prostaglandin metabolic process;0.0184080482757915!GO:0006692;prostanoid metabolic process;0.0184080482757915!GO:0000082;G1/S transition of mitotic cell cycle;0.0184618191230665!GO:0051059;NF-kappaB binding;0.0184618191230665!GO:0006733;oxidoreduction coenzyme metabolic process;0.0184961855027559!GO:0042158;lipoprotein biosynthetic process;0.018612645807755!GO:0006626;protein targeting to mitochondrion;0.0187850132577891!GO:0045792;negative regulation of cell size;0.0188086371411153!GO:0030145;manganese ion binding;0.0188885409758571!GO:0030659;cytoplasmic vesicle membrane;0.0190474103344674!GO:0006635;fatty acid beta-oxidation;0.019140289094426!GO:0051087;chaperone binding;0.0198904886645338!GO:0006897;endocytosis;0.0198904886645338!GO:0010324;membrane invagination;0.0198904886645338!GO:0006839;mitochondrial transport;0.0203252255426934!GO:0005832;chaperonin-containing T-complex;0.020348414474895!GO:0008270;zinc ion binding;0.0204921102518173!GO:0043492;ATPase activity, coupled to movement of substances;0.0205215300994932!GO:0016860;intramolecular oxidoreductase activity;0.0212046780102113!GO:0005684;U2-dependent spliceosome;0.0212046780102113!GO:0006354;RNA elongation;0.0213024243132751!GO:0005637;nuclear inner membrane;0.021400001850211!GO:0030522;intracellular receptor-mediated signaling pathway;0.0216258284206428!GO:0005765;lysosomal membrane;0.0218705407006655!GO:0030308;negative regulation of cell growth;0.0221426535281491!GO:0008632;apoptotic program;0.0224393400117398!GO:0043241;protein complex disassembly;0.0226677643637308!GO:0008652;amino acid biosynthetic process;0.0230752232593062!GO:0006769;nicotinamide metabolic process;0.0232229982964305!GO:0050811;GABA receptor binding;0.0232321990748377!GO:0031529;ruffle organization and biogenesis;0.0234753673547577!GO:0032940;secretion by cell;0.0236901657988183!GO:0006376;mRNA splice site selection;0.0237476427065534!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0237476427065534!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.0241161721780123!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0249487767930874!GO:0030384;phosphoinositide metabolic process;0.0251650621348586!GO:0043624;cellular protein complex disassembly;0.0255198016289115!GO:0044437;vacuolar part;0.0257581712709403!GO:0007040;lysosome organization and biogenesis;0.0260171868994286!GO:0003756;protein disulfide isomerase activity;0.0260245693176328!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0260245693176328!GO:0006767;water-soluble vitamin metabolic process;0.0260245693176328!GO:0007265;Ras protein signal transduction;0.0261686237073147!GO:0045334;clathrin-coated endocytic vesicle;0.0263550588591025!GO:0003684;damaged DNA binding;0.0264158706086909!GO:0009966;regulation of signal transduction;0.026501753506077!GO:0001953;negative regulation of cell-matrix adhesion;0.0267938899678614!GO:0008629;induction of apoptosis by intracellular signals;0.0271321342580933!GO:0051045;negative regulation of membrane protein ectodomain proteolysis;0.0272204818811154!GO:0051043;regulation of membrane protein ectodomain proteolysis;0.0272204818811154!GO:0007242;intracellular signaling cascade;0.0272410921931566!GO:0016791;phosphoric monoester hydrolase activity;0.0272922364508959!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0276183790587796!GO:0008064;regulation of actin polymerization and/or depolymerization;0.0276703941839905!GO:0004721;phosphoprotein phosphatase activity;0.0277739499778109!GO:0005862;muscle thin filament tropomyosin;0.0280716132766833!GO:0006739;NADP metabolic process;0.0280716132766833!GO:0006950;response to stress;0.0286962534806866!GO:0044433;cytoplasmic vesicle part;0.0287038041611542!GO:0016407;acetyltransferase activity;0.0288548045639167!GO:0030125;clathrin vesicle coat;0.0295121243597852!GO:0030665;clathrin coated vesicle membrane;0.0295121243597852!GO:0030865;cortical cytoskeleton organization and biogenesis;0.030123855217004!GO:0006779;porphyrin biosynthetic process;0.0305312729238964!GO:0033014;tetrapyrrole biosynthetic process;0.0305312729238964!GO:0006417;regulation of translation;0.0308707436002577!GO:0042168;heme metabolic process;0.030933661618508!GO:0006506;GPI anchor biosynthetic process;0.0309872051279641!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0310316903950713!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0311848444009788!GO:0046426;negative regulation of JAK-STAT cascade;0.0313182932453509!GO:0007179;transforming growth factor beta receptor signaling pathway;0.0313927788067067!GO:0006338;chromatin remodeling;0.0313927788067067!GO:0046870;cadmium ion binding;0.0313983324065392!GO:0046983;protein dimerization activity;0.0314231053978918!GO:0000075;cell cycle checkpoint;0.0314403966612326!GO:0008097;5S rRNA binding;0.0316400435149496!GO:0008033;tRNA processing;0.0321612592577848!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0333115852636197!GO:0016125;sterol metabolic process;0.0335481442567616!GO:0005874;microtubule;0.033616522454173!GO:0003955;NAD(P)H dehydrogenase (quinone) activity;0.0342712745705378!GO:0008168;methyltransferase activity;0.0357781442836671!GO:0019362;pyridine nucleotide metabolic process;0.0359468315084191!GO:0006505;GPI anchor metabolic process;0.0370388654978949!GO:0044452;nucleolar part;0.0374460106233532!GO:0016584;nucleosome positioning;0.037888989496498!GO:0006066;alcohol metabolic process;0.037997914544022!GO:0007033;vacuole organization and biogenesis;0.0391635544131201!GO:0030833;regulation of actin filament polymerization;0.0395700719369943!GO:0006643;membrane lipid metabolic process;0.0396218093746386!GO:0004722;protein serine/threonine phosphatase activity;0.0398059009060091!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0402469778110145!GO:0016741;transferase activity, transferring one-carbon groups;0.0404401851210694!GO:0030508;thiol-disulfide exchange intermediate activity;0.040783556631207!GO:0009081;branched chain family amino acid metabolic process;0.0408288143529174!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.041054841656209!GO:0006611;protein export from nucleus;0.0416137383057844!GO:0008022;protein C-terminus binding;0.0416614707173807!GO:0030128;clathrin coat of endocytic vesicle;0.0418776228420826!GO:0030669;clathrin-coated endocytic vesicle membrane;0.0418776228420826!GO:0030122;AP-2 adaptor complex;0.0418776228420826!GO:0031371;ubiquitin conjugating enzyme complex;0.0418776228420826!GO:0012506;vesicle membrane;0.0419953264635921!GO:0000287;magnesium ion binding;0.0424119806369723!GO:0008234;cysteine-type peptidase activity;0.0427051460335041!GO:0050790;regulation of catalytic activity;0.042732803768448!GO:0030503;regulation of cell redox homeostasis;0.0427824166692348!GO:0030911;TPR domain binding;0.0427824166692348!GO:0051098;regulation of binding;0.0431117057957473!GO:0000118;histone deacetylase complex;0.0432124373966549!GO:0017134;fibroblast growth factor binding;0.0432943363012768!GO:0007041;lysosomal transport;0.0432943363012768!GO:0031418;L-ascorbic acid binding;0.0437357733519108!GO:0043065;positive regulation of apoptosis;0.0438564002614851!GO:0043087;regulation of GTPase activity;0.0438564002614851!GO:0005581;collagen;0.0438955807757869!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0438955807757869!GO:0030984;kininogen binding;0.0445237805916807!GO:0004213;cathepsin B activity;0.0445237805916807!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.0445382395069749!GO:0032906;transforming growth factor-beta2 production;0.0449907050759386!GO:0032909;regulation of transforming growth factor-beta2 production;0.0449907050759386!GO:0045926;negative regulation of growth;0.0450586794727397!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0450586794727397!GO:0006261;DNA-dependent DNA replication;0.0451374345080035!GO:0006355;regulation of transcription, DNA-dependent;0.0453036647745346!GO:0007004;telomere maintenance via telomerase;0.0453445614932879!GO:0007030;Golgi organization and biogenesis;0.0453973269554607!GO:0043126;regulation of 1-phosphatidylinositol 4-kinase activity;0.0458963162441787!GO:0046813;virion attachment, binding of host cell surface receptor;0.0458963162441787!GO:0043128;positive regulation of 1-phosphatidylinositol 4-kinase activity;0.0458963162441787!GO:0005784;translocon complex;0.0461898583312254!GO:0006644;phospholipid metabolic process;0.0462895850868918!GO:0030032;lamellipodium biogenesis;0.0465281293535631!GO:0044255;cellular lipid metabolic process;0.0465533403085827!GO:0003678;DNA helicase activity;0.0466363896145667!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.046695302186795!GO:0031272;regulation of pseudopodium formation;0.0470626658527369!GO:0031269;pseudopodium formation;0.0470626658527369!GO:0031344;regulation of cell projection organization and biogenesis;0.0470626658527369!GO:0031268;pseudopodium organization and biogenesis;0.0470626658527369!GO:0031346;positive regulation of cell projection organization and biogenesis;0.0470626658527369!GO:0031274;positive regulation of pseudopodium formation;0.0470626658527369!GO:0004860;protein kinase inhibitor activity;0.0473109388887722!GO:0043130;ubiquitin binding;0.0473246875638201!GO:0032182;small conjugating protein binding;0.0473246875638201!GO:0031124;mRNA 3'-end processing;0.0473352445126676!GO:0009893;positive regulation of metabolic process;0.0473352445126676!GO:0031461;cullin-RING ubiquitin ligase complex;0.0480497186561124!GO:0001952;regulation of cell-matrix adhesion;0.0483951587056999!GO:0006519;amino acid and derivative metabolic process;0.0490828111721349!GO:0043068;positive regulation of programmed cell death;0.0490828111721349 | |||
|sample_id=11394 | |||
|sample_note= | |||
|sample_sex=unknown | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=gum | |||
|top_motifs=ZNF238:2.04479909951;NFIX:1.43506457913;TFAP4:1.37495569655;HES1:1.30513304233;NFATC1..3:1.02253140214;MTF1:1.01187643277;TFCP2:1.00283636277;PAX5:0.997102890892;SP1:0.971616716217;EBF1:0.958050999368;PATZ1:0.936912228629;GZF1:0.898860307659;TFAP2{A,C}:0.896307337767;GTF2A1,2:0.889839123551;MAZ:0.841523307569;TLX1..3_NFIC{dimer}:0.825542005071;AR:0.795440924407;GFI1B:0.771888926523;STAT1,3:0.755582523016;RXR{A,B,G}:0.74739323155;PDX1:0.73193891421;FOXO1,3,4:0.72445185994;bHLH_family:0.70617951735;ZNF423:0.686610992034;GTF2I:0.677817667696;NR3C1:0.667083694158;EN1,2:0.657534315774;NKX2-2,8:0.651711873217;MZF1:0.638492257218;TFDP1:0.585334624573;CEBPA,B_DDIT3:0.571170553405;MYBL2:0.550279001923;NKX2-1,4:0.535697920552;TFAP2B:0.532933749014;EGR1..3:0.525200011455;TOPORS:0.514021189633;HIC1:0.495729187847;TP53:0.469307777217;MYFfamily:0.466955327294;NFE2L2:0.45935457027;MED-1{core}:0.448127798775;TEAD1:0.434907642873;ZIC1..3:0.425995586015;ALX4:0.421594568045;XCPE1{core}:0.395710555556;GLI1..3:0.39553092347;HAND1,2:0.357450343074;AHR_ARNT_ARNT2:0.341295658906;MTE{core}:0.339475589812;YY1:0.321695160643;NFE2:0.320895851105;SOX5:0.319174127204;ATF6:0.313014132487;SREBF1,2:0.306465178973;HLF:0.298111386001;ZBTB6:0.297967338097;RBPJ:0.297616796106;UFEwm:0.29562485034;ESR1:0.295549274355;XBP1:0.293093313494;SOX17:0.277662205791;HOX{A6,A7,B6,B7}:0.275019306406;TBX4,5:0.272244704937;TGIF1:0.265097437091;ZFP161:0.249836635287;BACH2:0.23102843999;HNF4A_NR2F1,2:0.217747711174;NHLH1,2:0.208934196821;LHX3,4:0.199139782909;GFI1:0.193059918847;AIRE:0.149263172856;STAT5{A,B}:0.141798994279;SPZ1:0.126740998417;FOSL2:0.125881880073;ZNF143:0.124401294959;PRRX1,2:0.124142014633;ZNF148:0.12386120102;NR1H4:0.113010564317;PRDM1:0.111996537598;TAL1_TCF{3,4,12}:0.110537944349;FOX{F1,F2,J1}:0.10233344199;KLF4:0.0958684255563;FOXD3:0.0906975865546;NANOG{mouse}:0.0822092131102;FOX{I1,J2}:0.0770381188077;POU6F1:0.0707320560811;HOX{A5,B5}:0.0694448888463;ADNP_IRX_SIX_ZHX:0.0664022678675;ESRRA:0.0653076704845;NKX6-1,2:0.0617967190497;NKX3-1:0.0565108538223;HIF1A:0.0403424195004;MAFB:0.0263699704393;NRF1:0.0184627149933;HOX{A4,D4}:0.00548098462158;FOS_FOS{B,L1}_JUN{B,D}:-0.0141447479329;STAT2,4,6:-0.0377338891558;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.0408125117345;IRF1,2:-0.0470650983735;RORA:-0.0668170191745;HNF1A:-0.0698252648896;TBP:-0.0788865670713;RREB1:-0.096427711414;RFX1:-0.0975087778036;IKZF1:-0.10652264037;CREB1:-0.113506718115;REST:-0.114649987558;FOXN1:-0.124519766471;NFE2L1:-0.132376638241;MYB:-0.136869106429;TEF:-0.142791829987;PAX1,9:-0.144280235225;ATF4:-0.153044879573;ATF5_CREB3:-0.155245659322;PAX6:-0.165824458763;FOXA2:-0.182898843034;IRF7:-0.193359584483;FOX{D1,D2}:-0.204268821417;PAX4:-0.211196802638;GCM1,2:-0.21264551821;ARID5B:-0.220484810841;POU3F1..4:-0.228445229698;RFX2..5_RFXANK_RFXAP:-0.230197962227;NFY{A,B,C}:-0.255842988367;BPTF:-0.298340077302;HMX1:-0.300360856645;NANOG:-0.30548580413;NFIL3:-0.309149412912;ONECUT1,2:-0.315807148082;FOXQ1:-0.316451515788;MEF2{A,B,C,D}:-0.323606951002;ELK1,4_GABP{A,B1}:-0.337589178685;ALX1:-0.338552327501;HMGA1,2:-0.344199082365;SRF:-0.350265231954;PAX3,7:-0.354317464078;PPARG:-0.35489404143;JUN:-0.357457186219;GATA6:-0.379240999562;EVI1:-0.384417765278;BREu{core}:-0.386136373078;FOXL1:-0.390547484031;LEF1_TCF7_TCF7L1,2:-0.401887049267;NFKB1_REL_RELA:-0.419936015719;GATA4:-0.421901332574;DMAP1_NCOR{1,2}_SMARC:-0.423766812158;TLX2:-0.432984139047;RUNX1..3:-0.436948167254;CUX2:-0.454647383376;SMAD1..7,9:-0.467467939505;ETS1,2:-0.480807619141;SPI1:-0.484120614605;CRX:-0.501047285165;RXRA_VDR{dimer}:-0.504369780059;CDX1,2,4:-0.506531950066;FOXM1:-0.511464742085;ELF1,2,4:-0.526212445929;SPIB:-0.52793583923;ZBTB16:-0.53875551117;NKX3-2:-0.55681619852;NR6A1:-0.57189316644;PBX1:-0.585267479581;HSF1,2:-0.60249614287;NKX2-3_NKX2-5:-0.648781520026;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.66091120771;PAX2:-0.668721454537;MYOD1:-0.678472052481;POU5F1:-0.729614993937;FOXP3:-0.73005402293;FOXP1:-0.744891337066;E2F1..5:-0.750786658034;POU2F1..3:-0.754814278915;HOXA9_MEIS1:-0.759209922806;DBP:-0.761162627173;SOX2:-0.781215083653;HBP1_HMGB_SSRP1_UBTF:-0.782138039003;LMO2:-0.796508749777;ZNF384:-0.81360670685;ATF2:-0.817083544021;NR5A1,2:-0.818037290096;CDC5L:-0.818548092918;PAX8:-0.850836589049;T:-0.875660942566;OCT4_SOX2{dimer}:-0.897738528282;SNAI1..3:-0.91449216364;POU1F1:-0.928992178928;SOX{8,9,10}:-0.953283875875;ZEB1:-0.974078494396;PITX1..3:-1.01669414853;VSX1,2:-1.22706509923;IKZF2:-1.2960729425;EP300:-1.30427070852 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11394-118C8;search_select_hide=table117:FF:11394-118C8 | |||
}} | }} |
Latest revision as of 17:57, 4 June 2020
Name: | Fibroblast - Gingival, donor3 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs12006 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12006
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12006
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0486 |
10 | 10 | 0.144 |
100 | 100 | 0.428 |
101 | 101 | 0.764 |
102 | 102 | 0.429 |
103 | 103 | 0.17 |
104 | 104 | 0.897 |
105 | 105 | 0.657 |
106 | 106 | 0.24 |
107 | 107 | 0.669 |
108 | 108 | 0.835 |
109 | 109 | 0.385 |
11 | 11 | 0.313 |
110 | 110 | 0.429 |
111 | 111 | 0.121 |
112 | 112 | 0.277 |
113 | 113 | 4.82481e-4 |
114 | 114 | 0.166 |
115 | 115 | 0.8 |
116 | 116 | 0.911 |
117 | 117 | 0.389 |
118 | 118 | 0.33 |
119 | 119 | 0.0217 |
12 | 12 | 0.737 |
120 | 120 | 0.734 |
121 | 121 | 0.88 |
122 | 122 | 0.201 |
123 | 123 | 9.55217e-4 |
124 | 124 | 0.159 |
125 | 125 | 0.118 |
126 | 126 | 0.808 |
127 | 127 | 0.568 |
128 | 128 | 0.828 |
129 | 129 | 0.135 |
13 | 13 | 0.0189 |
130 | 130 | 0.0647 |
131 | 131 | 0.303 |
132 | 132 | 0.897 |
133 | 133 | 0.759 |
134 | 134 | 0.309 |
135 | 135 | 0.0316 |
136 | 136 | 0.197 |
137 | 137 | 0.0536 |
138 | 138 | 0.257 |
139 | 139 | 0.0069 |
14 | 14 | 0.328 |
140 | 140 | 0.255 |
141 | 141 | 0.00821 |
142 | 142 | 0.601 |
143 | 143 | 0.046 |
144 | 144 | 0.473 |
145 | 145 | 0.482 |
146 | 146 | 0.799 |
147 | 147 | 0.279 |
148 | 148 | 0.412 |
149 | 149 | 0.691 |
15 | 15 | 0.047 |
150 | 150 | 0.737 |
151 | 151 | 0.478 |
152 | 152 | 0.256 |
153 | 153 | 0.277 |
154 | 154 | 0.484 |
155 | 155 | 0.067 |
156 | 156 | 0.452 |
157 | 157 | 0.55 |
158 | 158 | 0.00201 |
159 | 159 | 0.243 |
16 | 16 | 0.81 |
160 | 160 | 0.293 |
161 | 161 | 0.491 |
162 | 162 | 0.462 |
163 | 163 | 0.5 |
164 | 164 | 0.768 |
165 | 165 | 0.354 |
166 | 166 | 0.89 |
167 | 167 | 0.0631 |
168 | 168 | 0.637 |
169 | 169 | 0.875 |
17 | 17 | 0.501 |
18 | 18 | 0.939 |
19 | 19 | 0.417 |
2 | 2 | 0.563 |
20 | 20 | 0.824 |
21 | 21 | 0.68 |
22 | 22 | 0.414 |
23 | 23 | 0.945 |
24 | 24 | 0.638 |
25 | 25 | 0.0888 |
26 | 26 | 0.214 |
27 | 27 | 0.828 |
28 | 28 | 0.292 |
29 | 29 | 0.512 |
3 | 3 | 0.303 |
30 | 30 | 0.259 |
31 | 31 | 0.925 |
32 | 32 | 0.0267 |
33 | 33 | 0.812 |
34 | 34 | 0.973 |
35 | 35 | 0.119 |
36 | 36 | 0.00328 |
37 | 37 | 0.931 |
38 | 38 | 0.349 |
39 | 39 | 0.954 |
4 | 4 | 0.116 |
40 | 40 | 0.0485 |
41 | 41 | 0.0585 |
42 | 42 | 0.292 |
43 | 43 | 0.296 |
44 | 44 | 0.0577 |
45 | 45 | 0.946 |
46 | 46 | 0.202 |
47 | 47 | 0.0183 |
48 | 48 | 0.163 |
49 | 49 | 0.119 |
5 | 5 | 0.234 |
50 | 50 | 0.354 |
51 | 51 | 0.618 |
52 | 52 | 0.751 |
53 | 53 | 0.353 |
54 | 54 | 0.933 |
55 | 55 | 0.659 |
56 | 56 | 0.591 |
57 | 57 | 0.365 |
58 | 58 | 0.0502 |
59 | 59 | 0.739 |
6 | 6 | 0.505 |
60 | 60 | 0.252 |
61 | 61 | 0.313 |
62 | 62 | 0.0499 |
63 | 63 | 0.773 |
64 | 64 | 0.308 |
65 | 65 | 0.61 |
66 | 66 | 0.966 |
67 | 67 | 0.374 |
68 | 68 | 0.592 |
69 | 69 | 0.884 |
7 | 7 | 0.0676 |
70 | 70 | 0.179 |
71 | 71 | 0.042 |
72 | 72 | 0.787 |
73 | 73 | 0.577 |
74 | 74 | 0.836 |
75 | 75 | 0.0655 |
76 | 76 | 0.861 |
77 | 77 | 0.77 |
78 | 78 | 0.0531 |
79 | 79 | 0.404 |
8 | 8 | 0.354 |
80 | 80 | 0.228 |
81 | 81 | 0.384 |
82 | 82 | 0.077 |
83 | 83 | 0.0252 |
84 | 84 | 0.959 |
85 | 85 | 0.753 |
86 | 86 | 0.842 |
87 | 87 | 0.101 |
88 | 88 | 0.669 |
89 | 89 | 0.38 |
9 | 9 | 0.753 |
90 | 90 | 0.0126 |
91 | 91 | 0.566 |
92 | 92 | 0.601 |
93 | 93 | 0.276 |
94 | 94 | 0.507 |
95 | 95 | 0.687 |
96 | 96 | 0.17 |
97 | 97 | 0.607 |
98 | 98 | 0.202 |
99 | 99 | 0.0126 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12006
FANTOM5 (FF) ontology
Direct parent terms
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0002320 (connective tissue cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
0000057 (fibroblast)
0002552 (fibroblast of gingiva)
UBERON: Anatomy
0000468 (multi-cellular organism)
0002384 (connective tissue)
0000033 (head)
0000479 (tissue)
0001007 (digestive system)
0000344 (mucosa)
0004121 (ectoderm-derived structure)
0000064 (organ part)
0004119 (endoderm-derived structure)
0000062 (organ)
0004111 (anatomical conduit)
0000475 (organism subdivision)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000481 (multi-tissue structure)
0004923 (organ component layer)
0000161 (orifice)
0001444 (subdivision of head)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0003729 (mouth mucosa)
0010317 (germ layer / neural crest derived structure)
0001555 (digestive tract)
0001828 (gingiva)
0001004 (respiratory system)
0000153 (anterior region of body)
0007811 (craniocervical region)
0000165 (mouth)
0000166 (oral opening)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000057 (fibroblast sample)
0000001 (sample)
0000063 (human fibroblast of gingiva sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)