FF:10775-110G1: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005415 | ||
| | |accession_numbers=CAGE;DRX007925;DRR008797;DRZ000222;DRZ001607;DRZ011572;DRZ012957 | ||
| | |ancestors_in_anatomy_facet= | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000542,CL:0000219,CL:0000945,CL:0000738,CL:0002087,CL:0002242,CL:0000255 | ||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:0060058,DOID:14566,DOID:0060083 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100104,FF:0101518 | |||
|comment= | |||
|created_by= | |||
|creation_date= | |||
| | |data_phase=2 | ||
| | |datafreeze_phase=2 | ||
|def= | |||
|expression_enrichment_score=chr19:19281060..19281078,-!p2@MEF2BNB-MEF2B,p2@MEF2B!2.71!507.27!MEF2B;;chr11:111249993..111250006,-!p1@POU2AF1!2.68!482.18!POU2AF1;;chr19:50922187..50922204,+!p1@SPIB!2.50!316.17!SPIB;;chr6:391743..391759,+!p1@IRF4!2.40!251.01!IRF4;;chr16:85932760..85932775,+!p1@IRF8!2.36!228.00!IRF8;;chr17:38020392..38020477,-!p1@IKZF3!1.95!87.45!IKZF3;;chr9:37034469..37034474,-!p1@PAX5!1.87!73.32!PAX5;;chr11:47400078..47400106,-!p1@SPI1!1.86!71.49!SPI1;;chr7:50348268..50348366,+!p4@IKZF1!1.82!65.40!IKZF1;;chr14:75988831..75988847,+!p2@BATF!1.77!58.46!BATF;;chr2:61108695..61108753,+!p1@REL!1.64!282.19!REL;;chr2:231090471..231090504,+!p2@SP140!1.63!41.65!SP140;;chr5:158526917..158526932,-!p1@EBF1!1.62!97.92!EBF1;;chr14:75988771..75988826,+!p1@BATF!1.62!53.10!BATF;;chrX:131623026..131623039,-!p5@MBNL3!1.62!40.80!MBNL3;;chr2:100759037..100759058,-!p2@AFF3!1.60!38.36!AFF3;;chr19:42636586..42636607,-!p1@POU2F2!1.55!93.29!POU2F2;;chr3:101546827..101546847,+!p2@NFKBIZ!1.55!48.23!NFKBIZ;;chr5:88178983..88179012,-!p1@MEF2C!1.51!229.70!MEF2C;;chr18:52989031..52989079,-!p2@TCF4!1.51!71.49!TCF4;;chr2:185463247..185463263,+!p1@ZNF804A!1.50!53.47!ZNF804A;;chr2:61108771..61108789,+!p4@REL!1.50!46.16!REL;;chr2:61108808..61108821,+!p3@REL!1.50!38.73!REL;;chr2:100759010..100759035,-!p1@AFF3!1.49!30.20!AFF3;;chr3:71355163..71355209,-!p5@FOXP1!1.48!39.70!FOXP1;;chr2:231090433..231090469,+!p1@SP140!1.48!29.11!SP140;;chr2:61108650..61108687,+!p2@REL!1.46!130.93!REL;;chr7:101460882..101460923,+!p5@CUX1!1.43!25.94!CUX1;;chr20:50159198..50159299,-!p1@NFATC2!1.42!36.17!NFATC2;;chr17:38020557..38020572,-!p4@IKZF3!1.40!23.99!IKZF3;;chr13:41593425..41593480,-!p1@ELF1!1.39!146.27!ELF1;;chr2:68592406..68592424,+!p1@PLEK!1.38!23.02!PLEK;;chr17:37934204..37934241,-!p3@IKZF3!1.37!22.41!IKZF3;;chr18:53089453..53089482,-!p11@TCF4!1.34!20.95!TCF4;;chr2:60780607..60780624,-!p2@BCL11A!1.33!60.90!BCL11A;;chr3:32023232..32023273,+!p1@ZNF860!1.33!29.11!ZNF860;;chr8:135577829..135577861,-!p6@ZFAT!1.32!20.10!ZFAT;;chr8:60031619..60031676,-!p1@TOX!1.31!41.41!TOX;;chr13:41593493..41593506,-!p8@ELF1!1.31!19.24!ELF1;;chr20:42295745..42295765,+!p1@MYBL2!1.27!282.19!MYBL2;;chr11:6947720..6947812,+!p1@ZNF215!1.27!22.65!ZNF215;;chr2:60778035..60778060,-!p4@BCL11A!1.27!21.07!BCL11A;;chr18:53089538..53089578,-!p14@TCF4!1.26!17.17!TCF4;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.26!17.05!ZBED1;;chr1:25256756..25256774,-!p1@RUNX3!1.24!30.45!RUNX3;;chr9:37034258..37034270,-!p3@PAX5!1.23!15.83!PAX5;;chr11:31832658..31832681,-!p1@PAX6!1.20!14.86!PAX6;;chr10:64576105..64576133,-!p1@EGR2!1.19!29.84!EGR2;;chr2:60781201..60781258,-!p3@BCL11A!1.19!14.62!BCL11A;;chr10:35415951..35415975,+!p8@CREM!1.18!19.61!CREM;;chrX:131623044..131623089,-!p1@MBNL3!1.17!57.24!MBNL3;;chrX:131622988..131623006,-!p8@MBNL3!1.17!13.76!MBNL3;;chr18:53089493..53089517,-!p15@TCF4!1.17!13.76!TCF4;;chr7:50343634..50343717,+!p2@IKZF1!1.17!13.76!IKZF1;;chr19:22235279..22235301,+!p1@ZNF257!1.16!25.21!ZNF257;;chr5:158526756..158526797,-!p3@EBF1!1.16!13.52!EBF1;;chr20:42295713..42295738,+!p2@MYBL2!1.15!76.97!MYBL2;;chr5:88179017..88179046,-!p2@MEF2C!1.15!51.88!MEF2C;;chr1:226595648..226595659,-!p3@PARP1!1.14!21.44!PARP1;;chr1:167298300..167298319,+!p2@POU2F1!1.14!12.67!POU2F1;;chr19:45579725..45579743,-!p1@ZNF296!1.13!56.51!ZNF296;;chr8:60031762..60031803,-!p3@TOX!1.13!18.39!TOX;;chr7:50344251..50344288,+!p3@IKZF1!1.12!12.18!IKZF1;;chr6:34204973..34204990,+!p4@HMGA1!1.11!158.45!HMGA1;;chr2:231090344..231090361,-!p3@SP110!1.10!11.45!SP110;;chr15:76629123..76629151,+!p1@ISL2!1.08!12.18!ISL2;;chr5:142814241..142814278,-!p12@NR3C1!1.08!11.08!NR3C1;;chr1:23857698..23857733,-!p1@E2F2!1.07!19.97!E2F2;;chr19:19976683..19976709,+!p1@ZNF253!1.06!47.13!ZNF253;;chr8:60031682..60031710,-!p2@TOX!1.06!17.05!TOX;;chr8:60031809..60031835,-!p4@TOX!1.05!13.15!TOX;;chr9:37034186..37034216,-!p2@PAX5!1.05!10.11!PAX5;;chr20:46130619..46130664,+!p1@NCOA3!1.03!263.44!NCOA3;;chr4:185395590..185395627,-!p3@IRF2!1.03!12.18!IRF2;;chr18:53257068..53257086,-!p12@TCF4!1.01!12.91!TCF4;;chr18:52989001..52989030,-!p10@TCF4!1.01!10.23!TCF4;;chr17:37934188..37934202,-!p8@IKZF3!1.01!9.13!IKZF3;;chr3:71180051..71180085,-!p21@FOXP1!1.01!9.13!FOXP1;;chrX:147582254..147582320,+!p1@AFF2!1.01!9.13!AFF2;;chr2:60780753..60780800,-!p1@BCL11A!1.00!44.94!BCL11A;;chr6:144385698..144385742,-!p2@PLAGL1!1.00!10.96!PLAGL1;;chr5:158524625..158524669,-!p6@EBF1!1.00!9.01!EBF1;;chr11:31832807..31832823,-!p4@PAX6!1.00!9.01!PAX6;;chr7:101459230..101459243,+!p2@CUX1!0.99!43.97!CUX1;;chrX:131622958..131622978,-!p3@MBNL3!0.99!11.08!MBNL3;;chr11:19262461..19262476,-!p5@E2F8!0.99!8.77!E2F8;;chr2:68592394..68592405,+!p2@PLEK!0.99!8.77!PLEK;;chr3:187463248..187463264,-!p1@BCL6!0.98!187.80!BCL6;;chr12:54447599..54447630,+!p3@HOXC4!0.98!10.47!HOXC4;;chr9:37027156..37027193,-!p4@PAX5!0.98!8.65!PAX5;;chr7:64126535..64126559,+!p2@ZNF107!0.97!18.27!ZNF107;;chr18:53089521..53089533,-!p22@TCF4!0.97!8.40!TCF4;;chr20:46130672..46130686,+!p2@NCOA3!0.96!37.76!NCOA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| |||
| | |ffid_belonging_in_development=CL:0000134,CL:0000051 | ||
| | |||
| | |||
| | |||
| | |||
| | |||
| | |||
|fonse_cell_line=FF:0100104 | |fonse_cell_line=FF:0100104 | ||
|fonse_cell_line_closure=FF:0100104 | |fonse_cell_line_closure=FF:0100104 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/lymphoma%252c%2520malignant%252c%2520hairy%2520B-cell%2520cell%2520line%253aMLMA.CNhs11935.10775-110G1.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/lymphoma%252c%2520malignant%252c%2520hairy%2520B-cell%2520cell%2520line%253aMLMA.CNhs11935.10775-110G1.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/lymphoma%252c%2520malignant%252c%2520hairy%2520B-cell%2520cell%2520line%253aMLMA.CNhs11935.10775-110G1.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/lymphoma%252c%2520malignant%252c%2520hairy%2520B-cell%2520cell%2520line%253aMLMA.CNhs11935.10775-110G1.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/lymphoma%252c%2520malignant%252c%2520hairy%2520B-cell%2520cell%2520line%253aMLMA.CNhs11935.10775-110G1.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10775-110G1 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0101518 | |||
|is_obsolete= | |||
|library_id=CNhs11935 | |||
|library_id_phase_based=2:CNhs11935 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10775 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10775 | |||
|name=lymphoma, malignant, hairy B-cell cell line:MLMA | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11935,LSID835,release010,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,1.25059999169648,0,0,0,0,0,0.0120427008616125,0.135252835731554,-0.224920728010341,-0.282403560576942,0,0,0,0.229264245600656,0,0,0,0,0,0,0.206546054915368,0,0,-0.153323010348428,0,0,0,0.0249562850978746,0.777680258486926,0.0372949394634965,0,0,-0.132956589778862,0,0,0,0,0,0,0,0,0,0,0,0,-0.147129033399494,0,0,0,0,0,0,0,0,0.123496037643689,0,0,0,0,0,-0.0839305477320758,0,-0.0969923612426051,0,0,-0.097343627213097,0,0,0,0,0,0,0,0,0.0499125701957491,0,0.135252835731554,0.0473377718500464,0,0,0,0,0,0,0.0249562850978746,0,0,0,0,0,-0.283391016988998,0,0,0,-0.00853425661607608,-0.161284832500119,0.114964189715823,0,0.0473377718500464,0,0.0372174844938476,-0.138477200800895,0,0,0,0,0,0,0.0946755437000927,0,0,0,0,0,0,0,0,0,0,0.194566902243988,0.238235743043069,0,0,-0.12273585496983,-0.319943576283781,0,0,0,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0.0946755437000927,0.0372174844938476,0,0,0.172360730947999,0,0,0,0,0,0,0,0,-0.247178875285564,0,-0.424173648556259,0.124254371185739,0.0249562850978746,0.0946755437000927,-0.279568028153047,0.0499125701957491,0,0,0,0.0499125701957491,0,0.0946755437000927,0.135252835731554,0,-0.128119866952565,0,-0.0504125515893149,0.00225628699181639,0,0,0,-0.0186252810838506,-0.170219395166853,0,-0.055140189627975,-0.0184316908816191,0,0.0499125701957491,0,0,-0.109531211783389,0,0.0143733519378134,-0.0827201683234173,0,-0.552614358341728,0.0031079113033691,0,0,0,-0.0021093490905625,0.223217388218056,0,0.0946755437000927,-0.121779851751874,0.220340502465065,0,0,-0.391044581551635,0.135252835731554,-0.431744207668305,-0.0604397418968705,0,0.0389845071360059,0,0,0,0,0,0,0,0,0,0,0,-0.0574934668214365,0.0851868825741426,-0.000214045370590929,0,0,0,-0.49090513133014,0,0,-0.373286155956567,-0.219719406289112,-0.0325512939609889,0.00159882894203622,0,-0.0346202133007024,-0.121218138581991,-0.419881804788233,-0.0274497432731754,-0.147401849371139,-0.189981719549847,0,-0.283391016988998,-0.691597085413919,0.0299851865943161,-0.434908995121025,-0.116224555648628,-1.18149593809136,0.0500817354661978,0,0.0499125701957491,-0.0775089264793031,-0.295515911288008,0,0.0533272008833998,-0.0579319716892436,0.114880144913539,-0.59869337952779,-0.809206926916503,-0.21171558465303,-0.245675137779163,-0.0395325284566706,-0.457436452896595,0,-0.396616039805825,0,0,-0.0877514257027229,-0.0484158382638653,-0.118106449422319,0.115321913464635,-0.0336208207788344,0.0520569823378608,-0.0683442610773682,0,-0.753125778993109,-0.330735095323456,0,0,-0.283355113358365,0,0,0.334490538494362,0,0,0.170678224486526,-0.148290330283101,-0.0604948306075462,0,-0.0324791809513471,0.0499125701957491,0.0311195339868616,0,-0.0489632383385237,-0.0771347185899981,0.0172067667558627,-0.229180468069098,0,-0.0289327081395552,-0.103041085342491,-0.164990696339003,-0.372482235195988,-0.00853425661607608,0.0729083082757179,-0.00774997951391898,0.0192692235666794,-0.788939864790226,-0.0826262473191057,-0.0881268324752877,-0.120822509869342,-0.347510306369539,0.0708651197069436,-0.0970784364096813,-0.21309893867331,0.0413051838673417,-0.359243188230143,0,0.110230180403105,0,0.193368744533284,-0.368073020525242,0.743972894102027,0.179527141871538,0,-0.26466555705951,0.00685049728562825,0,-0.363098636462107,0,0.0499125701957491,-0.0151142476030853,-0.697695966512583,0.605394618853829,-0.0357164292215106,0,-0.790080158389657,0,0,-0.264915576850171,0.00275970527868075,0.0946755437000927,0.137580035503615,0.0807593947072007,0.0520724563990689,0.01928176229662,0.0946755437000927,0,-0.645700337992725,0,0,-0.511252520117938,-0.107194241707366,0.183596918092816,0.574317647332828,0,-0.108622809454255,0,0,0.117894351547872,0.700630672236407,-0.068568881858239,0,0,-0.115996539744218,-0.116628112990133,0,0.133518137324046,0,-0.0345562330068291,0,-0.0589565109853561,0,0,0.0171416117945006,0,0,0.171749785216608,-0.0870638165072372,0,-0.179620349117759,0,0,0,0,0,0,0,0,0.0879153619240078,-0.056253955557224,0.083528639238948,0,0,0.0249562850978746,0,0.350057988104115,-0.108561018394631,0.0946755437000927,-0.0819501363018826,0,0,0,0,-0.0861409897892114,0,0,0.0861803654739995,0.0473377718500464,0.114630273894335,-0.022810162105812,0,0,0,-0.27695440160179,0,0,0,0,0.219009090072382,0.135252835731554,0,-0.537254629686287,0,-0.0997505141453923,-0.0815818795468414,0,0.179099975568699,-0.0119374134017143,-1.30962034064846,0,0,-0.261347131789888,0,0,0.442743802855416,0,0,-0.0209247759461169,0,0,0,0,0.0499125701957491,0.0946755437000927,0.0239212306433138,0,0,0,0,0,0,0,0,0,0,0,-0.133261153759069,0.0430287790730436,0,0,0,0,0,0,0,0.0232317487711432,0.146819836972355,0,0,0,0,0,0.0499125701957491,0,0,-0.0201171874814157,0,0,0,0,0,-0.0969923612426051,0,0.135252835731554,0,0,-0.564807121153884,0,0,-0.182686588493421,0,0,0,0,0,0,0,0,0,1.25059999169648,0,0,0,0.1721030314776,-0.406522976143905,0,0,0,0,0,0.135252835731554,0,-0.224920728010341,0,0,0,0,-0.113884373708977,0,0,0,0.162973128920054,0,0.0120427008616125,0,0.0499125701957491,0,0,0,0.0499125701957491,0.0861803654739995,0.0249562850978746,0,0,0,0,0,0,0,0,0,0,0,0,0,0.149922109317808,0,-0.28720751597291,-0.123202864573785,0,0,-0.232628352633041,0,0,0,0.0249562850978746,0,0,0.03628599383725,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.238235743043069,0,0,0,0,0,0,-0.0140301556348685,0,0,0,0,0,0,0,0.0372949394634965,0,0.893264259313532,0.116014419600455,0,0,0,0.0311296446929192,0,0,-0.140265781900186,-0.235882627973101,-0.170214858033552,0,0,0,-0.054385572482455,0,0,-0.0820564584332857,0,-0.0667773874189013,0.0499125701957491,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.153323010348428,0,0,0.0499125701957491,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0946755437000927,0,0.0499125701957491,0,0,0,0,0,0,0,0.0133264085746299,0.369163624268319,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.347185070813426,0,0,0,0,0.345947048864674,-0.08001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| |||
|rna_box=110 | |||
|rna_catalog_number= | |||
|rna_concentration=0.34905 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=1.88 | |||
|rna_od260/280=2.05 | |||
|rna_position=G1 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=110G1 | |||
|rna_weight_ug=9.42435 | |||
|sample_age=32 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=jcrb0146 | |||
|sample_cell_line=MLMA | |||
|sample_cell_lot= | |||
|sample_cell_type=b cell | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=JAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=lymphoma, malignant, hairy B-cell | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=J | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.96277558302735e-275!GO:0043227;membrane-bound organelle;5.1762671562339e-241!GO:0043231;intracellular membrane-bound organelle;1.54350607320952e-240!GO:0043226;organelle;5.35209723778938e-235!GO:0043229;intracellular organelle;3.77630172568343e-234!GO:0044422;organelle part;3.99701813081681e-168!GO:0044446;intracellular organelle part;3.51851733444237e-166!GO:0005737;cytoplasm;3.4751406801133e-158!GO:0005634;nucleus;1.67863310055655e-129!GO:0032991;macromolecular complex;9.63910291916613e-129!GO:0044237;cellular metabolic process;9.1475582241417e-117!GO:0044238;primary metabolic process;5.69147117139488e-113!GO:0044444;cytoplasmic part;1.96787691954366e-110!GO:0044428;nuclear part;9.99745420272869e-107!GO:0043170;macromolecule metabolic process;1.6124943719649e-106!GO:0030529;ribonucleoprotein complex;1.76732214876421e-99!GO:0003723;RNA binding;3.49445440906837e-94!GO:0043233;organelle lumen;9.98273753925745e-92!GO:0031974;membrane-enclosed lumen;9.98273753925745e-92!GO:0005739;mitochondrion;5.10630408375796e-79!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.90885491497882e-73!GO:0043283;biopolymer metabolic process;1.14686672909946e-72!GO:0006396;RNA processing;1.42640530581468e-70!GO:0010467;gene expression;3.71220792555799e-68!GO:0043234;protein complex;2.23267675542243e-67!GO:0031981;nuclear lumen;4.8329445061145e-62!GO:0005515;protein binding;2.05598127058842e-61!GO:0006412;translation;2.83446756396648e-61!GO:0044429;mitochondrial part;7.35874091006086e-55!GO:0005840;ribosome;1.72363370588079e-53!GO:0016071;mRNA metabolic process;3.25778065169708e-53!GO:0031967;organelle envelope;4.01529882310829e-52!GO:0006259;DNA metabolic process;7.64316943975623e-52!GO:0031975;envelope;1.02840557240777e-51!GO:0003676;nucleic acid binding;1.23175432160113e-49!GO:0006397;mRNA processing;1.50344850827037e-46!GO:0044249;cellular biosynthetic process;2.4717956988979e-46!GO:0008380;RNA splicing;2.71369296836528e-46!GO:0019538;protein metabolic process;4.08080021609388e-46!GO:0003735;structural constituent of ribosome;5.35245322440725e-46!GO:0033036;macromolecule localization;9.51837203418465e-46!GO:0031090;organelle membrane;2.27413116419935e-45!GO:0009058;biosynthetic process;6.53698548690852e-45!GO:0015031;protein transport;1.95922227695114e-44!GO:0009059;macromolecule biosynthetic process;6.32553261906258e-42!GO:0044267;cellular protein metabolic process;7.97429004099839e-42!GO:0045184;establishment of protein localization;1.7189773734261e-41!GO:0046907;intracellular transport;2.38532919173915e-41!GO:0008104;protein localization;5.83133331196301e-41!GO:0044260;cellular macromolecule metabolic process;6.24198114385936e-41!GO:0006996;organelle organization and biogenesis;6.96773714081444e-41!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.04872413556453e-40!GO:0033279;ribosomal subunit;1.25569076797298e-39!GO:0005654;nucleoplasm;1.45837936620884e-39!GO:0043228;non-membrane-bound organelle;1.8951543474839e-39!GO:0043232;intracellular non-membrane-bound organelle;1.8951543474839e-39!GO:0016043;cellular component organization and biogenesis;1.07078887876814e-38!GO:0065003;macromolecular complex assembly;4.54066835489667e-36!GO:0005829;cytosol;4.88983255778318e-36!GO:0007049;cell cycle;5.48900929752611e-36!GO:0006974;response to DNA damage stimulus;6.94713235328281e-36!GO:0016070;RNA metabolic process;1.11640203853123e-35!GO:0005681;spliceosome;6.37211497775109e-35!GO:0005740;mitochondrial envelope;1.72934372267208e-34!GO:0006886;intracellular protein transport;3.32317353629899e-33!GO:0000166;nucleotide binding;1.50913530452167e-32!GO:0019866;organelle inner membrane;2.89349523974741e-32!GO:0031966;mitochondrial membrane;3.55799224611125e-32!GO:0000278;mitotic cell cycle;1.53617936003817e-31!GO:0005694;chromosome;1.59151873913703e-31!GO:0022607;cellular component assembly;2.56358609920576e-31!GO:0022402;cell cycle process;1.47473385042055e-30!GO:0006281;DNA repair;5.9532737682032e-30!GO:0005743;mitochondrial inner membrane;6.29429591592355e-30!GO:0051649;establishment of cellular localization;1.73208757544793e-29!GO:0044451;nucleoplasm part;1.74063398675578e-29!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.03490909479809e-28!GO:0051641;cellular localization;1.53973162696134e-28!GO:0022403;cell cycle phase;3.06442668361818e-28!GO:0044427;chromosomal part;3.09387853789019e-27!GO:0000087;M phase of mitotic cell cycle;4.18950747158588e-27!GO:0007067;mitosis;1.54988947649969e-26!GO:0044445;cytosolic part;1.13041686752804e-25!GO:0005730;nucleolus;2.21427453924768e-25!GO:0000279;M phase;5.95540270067222e-25!GO:0031980;mitochondrial lumen;1.0394587417462e-23!GO:0005759;mitochondrial matrix;1.0394587417462e-23!GO:0017111;nucleoside-triphosphatase activity;1.11908334758193e-23!GO:0044455;mitochondrial membrane part;1.88694467368345e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;2.29826192238992e-23!GO:0016462;pyrophosphatase activity;2.54426582114436e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;3.51593290793822e-23!GO:0009719;response to endogenous stimulus;5.01355549457326e-23!GO:0051276;chromosome organization and biogenesis;6.29594266658444e-23!GO:0005524;ATP binding;6.6587516077887e-23!GO:0032553;ribonucleotide binding;1.52288671956313e-22!GO:0032555;purine ribonucleotide binding;1.52288671956313e-22!GO:0032559;adenyl ribonucleotide binding;2.76399900729187e-22!GO:0016874;ligase activity;2.96605900770194e-22!GO:0006119;oxidative phosphorylation;3.17395700431907e-22!GO:0006512;ubiquitin cycle;6.44472014505703e-22!GO:0017076;purine nucleotide binding;7.31229796977611e-22!GO:0022618;protein-RNA complex assembly;8.33864004212025e-22!GO:0030554;adenyl nucleotide binding;2.62623304806105e-21!GO:0006260;DNA replication;3.11538888210101e-21!GO:0051301;cell division;3.47871868460245e-21!GO:0044265;cellular macromolecule catabolic process;9.4015604194171e-21!GO:0006511;ubiquitin-dependent protein catabolic process;1.44542008137816e-20!GO:0051603;proteolysis involved in cellular protein catabolic process;1.47966997508569e-20!GO:0019941;modification-dependent protein catabolic process;1.67440060842851e-20!GO:0043632;modification-dependent macromolecule catabolic process;1.67440060842851e-20!GO:0015934;large ribosomal subunit;2.21701634526809e-20!GO:0015935;small ribosomal subunit;2.47275779438683e-20!GO:0044257;cellular protein catabolic process;5.44455694763099e-20!GO:0016887;ATPase activity;4.10252392622071e-19!GO:0042254;ribosome biogenesis and assembly;4.96005651008372e-19!GO:0006457;protein folding;9.52109204427584e-19!GO:0043285;biopolymer catabolic process;1.12793704501508e-18!GO:0005635;nuclear envelope;1.84264062938575e-18!GO:0042623;ATPase activity, coupled;1.88213589452332e-18!GO:0008134;transcription factor binding;3.889731130904e-18!GO:0006605;protein targeting;5.12460828012296e-18!GO:0031965;nuclear membrane;5.25836741352179e-18!GO:0000502;proteasome complex (sensu Eukaryota);1.20067929283143e-17!GO:0005746;mitochondrial respiratory chain;1.22019838644338e-17!GO:0016604;nuclear body;2.5101328538795e-17!GO:0044248;cellular catabolic process;2.94152147972641e-17!GO:0000398;nuclear mRNA splicing, via spliceosome;3.71145947783612e-17!GO:0000375;RNA splicing, via transesterification reactions;3.71145947783612e-17!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;3.71145947783612e-17!GO:0012505;endomembrane system;8.80723678723431e-17!GO:0009057;macromolecule catabolic process;9.61765814514571e-17!GO:0008135;translation factor activity, nucleic acid binding;1.28673991834266e-16!GO:0044453;nuclear membrane part;3.34549372658353e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;4.89520800754666e-16!GO:0005761;mitochondrial ribosome;5.87317985728531e-16!GO:0000313;organellar ribosome;5.87317985728531e-16!GO:0006913;nucleocytoplasmic transport;8.22932248270817e-16!GO:0050136;NADH dehydrogenase (quinone) activity;1.30454388499806e-15!GO:0003954;NADH dehydrogenase activity;1.30454388499806e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.30454388499806e-15!GO:0006323;DNA packaging;1.78478464093981e-15!GO:0030163;protein catabolic process;1.78478464093981e-15!GO:0004386;helicase activity;1.84548650622987e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.69688310205192e-15!GO:0051169;nuclear transport;3.19346653743675e-15!GO:0005643;nuclear pore;9.92614471110556e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.19456597674168e-14!GO:0012501;programmed cell death;1.65747102839351e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.90797663528961e-14!GO:0006915;apoptosis;1.95730599222681e-14!GO:0006403;RNA localization;2.43174911427324e-14!GO:0006399;tRNA metabolic process;3.48779338911204e-14!GO:0050657;nucleic acid transport;3.79739477930612e-14!GO:0051236;establishment of RNA localization;3.79739477930612e-14!GO:0050658;RNA transport;3.79739477930612e-14!GO:0042775;organelle ATP synthesis coupled electron transport;3.84526316144049e-14!GO:0042773;ATP synthesis coupled electron transport;3.84526316144049e-14!GO:0043412;biopolymer modification;4.72891698131259e-14!GO:0051186;cofactor metabolic process;6.4702954123485e-14!GO:0008026;ATP-dependent helicase activity;9.10963110623464e-14!GO:0030964;NADH dehydrogenase complex (quinone);1.17730106189547e-13!GO:0045271;respiratory chain complex I;1.17730106189547e-13!GO:0005747;mitochondrial respiratory chain complex I;1.17730106189547e-13!GO:0006413;translational initiation;1.42393094858647e-13!GO:0051726;regulation of cell cycle;1.47591072108155e-13!GO:0000074;regulation of progression through cell cycle;1.94362751273401e-13!GO:0051082;unfolded protein binding;2.33011224685472e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;3.12427289406724e-13!GO:0000785;chromatin;4.25385820503555e-13!GO:0006364;rRNA processing;6.59080920858848e-13!GO:0016607;nuclear speck;8.03017227973296e-13!GO:0016568;chromatin modification;8.74129633551218e-13!GO:0065002;intracellular protein transport across a membrane;1.1102784735147e-12!GO:0016779;nucleotidyltransferase activity;1.11775690403537e-12!GO:0008219;cell death;1.11775690403537e-12!GO:0016265;death;1.11775690403537e-12!GO:0016072;rRNA metabolic process;1.30266387856237e-12!GO:0006446;regulation of translational initiation;1.54105357432513e-12!GO:0003743;translation initiation factor activity;1.60206512581957e-12!GO:0046930;pore complex;2.26462803408493e-12!GO:0048770;pigment granule;2.67412262106022e-12!GO:0042470;melanosome;2.67412262106022e-12!GO:0006261;DNA-dependent DNA replication;3.11158781058942e-12!GO:0051028;mRNA transport;3.37559181743269e-12!GO:0017038;protein import;4.50809464300559e-12!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;5.48281849198287e-12!GO:0000775;chromosome, pericentric region;5.64893063808013e-12!GO:0003712;transcription cofactor activity;6.6738907094161e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.03194897803526e-11!GO:0048193;Golgi vesicle transport;1.08775106945809e-11!GO:0006464;protein modification process;1.2873437237492e-11!GO:0009259;ribonucleotide metabolic process;1.94630683586137e-11!GO:0008639;small protein conjugating enzyme activity;2.01552480538239e-11!GO:0006732;coenzyme metabolic process;3.4752140887531e-11!GO:0006163;purine nucleotide metabolic process;3.47837601597259e-11!GO:0043687;post-translational protein modification;3.65155909751292e-11!GO:0004842;ubiquitin-protein ligase activity;4.69457457794584e-11!GO:0050794;regulation of cellular process;5.16843235057272e-11!GO:0016879;ligase activity, forming carbon-nitrogen bonds;7.57108408208422e-11!GO:0006333;chromatin assembly or disassembly;8.61508812024144e-11!GO:0006164;purine nucleotide biosynthetic process;8.96801181633456e-11!GO:0009055;electron carrier activity;9.58140302289619e-11!GO:0065004;protein-DNA complex assembly;1.46903280114969e-10!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.46903280114969e-10!GO:0009260;ribonucleotide biosynthetic process;1.79233087709122e-10!GO:0044432;endoplasmic reticulum part;2.4721168075099e-10!GO:0019222;regulation of metabolic process;2.53342364394835e-10!GO:0019787;small conjugating protein ligase activity;2.53342364394835e-10!GO:0043566;structure-specific DNA binding;4.21923508200878e-10!GO:0009150;purine ribonucleotide metabolic process;6.07586477676999e-10!GO:0042981;regulation of apoptosis;6.75443360857809e-10!GO:0005819;spindle;7.06720849378844e-10!GO:0043067;regulation of programmed cell death;9.00113499366856e-10!GO:0006366;transcription from RNA polymerase II promoter;9.92594711627329e-10!GO:0003697;single-stranded DNA binding;1.04687922174091e-09!GO:0009152;purine ribonucleotide biosynthetic process;1.5834630609903e-09!GO:0000075;cell cycle checkpoint;1.58436903955558e-09!GO:0006461;protein complex assembly;1.69135396971187e-09!GO:0005783;endoplasmic reticulum;1.69616351242059e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.75642863860071e-09!GO:0004812;aminoacyl-tRNA ligase activity;1.75642863860071e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.75642863860071e-09!GO:0007005;mitochondrion organization and biogenesis;2.13542038738363e-09!GO:0030532;small nuclear ribonucleoprotein complex;3.08696708871196e-09!GO:0043038;amino acid activation;3.30280701916851e-09!GO:0006418;tRNA aminoacylation for protein translation;3.30280701916851e-09!GO:0043039;tRNA aminoacylation;3.30280701916851e-09!GO:0009056;catabolic process;3.35412989958929e-09!GO:0016787;hydrolase activity;4.31814147455645e-09!GO:0051246;regulation of protein metabolic process;5.21318728594399e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;6.01552471235995e-09!GO:0015630;microtubule cytoskeleton;6.40793278600092e-09!GO:0009060;aerobic respiration;7.25045320719097e-09!GO:0031323;regulation of cellular metabolic process;1.04877329104693e-08!GO:0008565;protein transporter activity;1.0532879728564e-08!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.10317441112535e-08!GO:0051325;interphase;1.185901120721e-08!GO:0005657;replication fork;1.34277911470479e-08!GO:0051170;nuclear import;1.617280511288e-08!GO:0007051;spindle organization and biogenesis;1.80563172781996e-08!GO:0005789;endoplasmic reticulum membrane;1.83995778003447e-08!GO:0016881;acid-amino acid ligase activity;1.90713754328979e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.9576427101061e-08!GO:0015078;hydrogen ion transmembrane transporter activity;2.20844471908356e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.91324036099395e-08!GO:0019829;cation-transporting ATPase activity;2.99502379817682e-08!GO:0045333;cellular respiration;3.66864887926393e-08!GO:0051188;cofactor biosynthetic process;4.0327973324887e-08!GO:0051329;interphase of mitotic cell cycle;4.12765321353731e-08!GO:0006084;acetyl-CoA metabolic process;4.20427118207561e-08!GO:0016740;transferase activity;4.34426834818371e-08!GO:0006606;protein import into nucleus;4.9497408745302e-08!GO:0006099;tricarboxylic acid cycle;4.9497408745302e-08!GO:0046356;acetyl-CoA catabolic process;4.9497408745302e-08!GO:0003713;transcription coactivator activity;4.99960589366122e-08!GO:0005813;centrosome;5.48343264474099e-08!GO:0005839;proteasome core complex (sensu Eukaryota);6.63274930064569e-08!GO:0003899;DNA-directed RNA polymerase activity;7.00232734246519e-08!GO:0000245;spliceosome assembly;7.88131946394952e-08!GO:0009141;nucleoside triphosphate metabolic process;8.70539828114845e-08!GO:0008094;DNA-dependent ATPase activity;8.84449421372659e-08!GO:0009199;ribonucleoside triphosphate metabolic process;8.93532799301714e-08!GO:0006350;transcription;1.0280601036434e-07!GO:0009142;nucleoside triphosphate biosynthetic process;1.05908532867872e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.05908532867872e-07!GO:0030120;vesicle coat;1.09798471368225e-07!GO:0030662;coated vesicle membrane;1.09798471368225e-07!GO:0032446;protein modification by small protein conjugation;1.13341378824538e-07!GO:0015986;ATP synthesis coupled proton transport;1.20830867737545e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.20830867737545e-07!GO:0005815;microtubule organizing center;1.2844538980028e-07!GO:0006888;ER to Golgi vesicle-mediated transport;1.44544428407344e-07!GO:0016567;protein ubiquitination;1.98261829114286e-07!GO:0016563;transcription activator activity;1.99672079262371e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.99672079262371e-07!GO:0009144;purine nucleoside triphosphate metabolic process;1.99672079262371e-07!GO:0007059;chromosome segregation;2.40916073669805e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.45866644712373e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.45866644712373e-07!GO:0007088;regulation of mitosis;2.66212425495262e-07!GO:0004298;threonine endopeptidase activity;3.00321877325392e-07!GO:0003724;RNA helicase activity;3.39791297173323e-07!GO:0009117;nucleotide metabolic process;4.04713626794655e-07!GO:0006310;DNA recombination;4.13171617252773e-07!GO:0016192;vesicle-mediated transport;4.14764874940583e-07!GO:0006302;double-strand break repair;4.27970843798907e-07!GO:0009109;coenzyme catabolic process;4.5642576788591e-07!GO:0051187;cofactor catabolic process;6.03282155693439e-07!GO:0045259;proton-transporting ATP synthase complex;6.10155209753144e-07!GO:0000151;ubiquitin ligase complex;6.28073630609973e-07!GO:0006754;ATP biosynthetic process;6.77872954183538e-07!GO:0006753;nucleoside phosphate metabolic process;6.77872954183538e-07!GO:0005794;Golgi apparatus;6.84054201551548e-07!GO:0046034;ATP metabolic process;7.24856866839461e-07!GO:0048475;coated membrane;7.67992143043529e-07!GO:0030117;membrane coat;7.67992143043529e-07!GO:0051168;nuclear export;7.77290631494324e-07!GO:0010468;regulation of gene expression;8.44982215827258e-07!GO:0006334;nucleosome assembly;9.10977490814976e-07!GO:0006752;group transfer coenzyme metabolic process;1.08399973734425e-06!GO:0006793;phosphorus metabolic process;1.13040794211789e-06!GO:0006796;phosphate metabolic process;1.13040794211789e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.13040794211789e-06!GO:0031497;chromatin assembly;1.19668278231865e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.59204071865809e-06!GO:0019899;enzyme binding;1.84324778365654e-06!GO:0007249;I-kappaB kinase/NF-kappaB cascade;1.95189723309412e-06!GO:0003690;double-stranded DNA binding;2.01315418911172e-06!GO:0009108;coenzyme biosynthetic process;2.02147738684587e-06!GO:0044452;nucleolar part;2.04188001340177e-06!GO:0016469;proton-transporting two-sector ATPase complex;2.39403963574678e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.40879548072089e-06!GO:0006417;regulation of translation;2.60488176442263e-06!GO:0000776;kinetochore;3.29677288974112e-06!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.3036730944027e-06!GO:0016310;phosphorylation;3.77733568891038e-06!GO:0050789;regulation of biological process;3.77733568891038e-06!GO:0006839;mitochondrial transport;4.105630129093e-06!GO:0008033;tRNA processing;4.84257146720427e-06!GO:0031324;negative regulation of cellular metabolic process;5.18179501755763e-06!GO:0016741;transferase activity, transferring one-carbon groups;5.94154498652817e-06!GO:0043623;cellular protein complex assembly;6.61975567848553e-06!GO:0005793;ER-Golgi intermediate compartment;7.00269968405685e-06!GO:0004527;exonuclease activity;7.03905796347182e-06!GO:0051052;regulation of DNA metabolic process;1.02419101571134e-05!GO:0043069;negative regulation of programmed cell death;1.03923489125587e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.06459991001779e-05!GO:0005667;transcription factor complex;1.06746825332509e-05!GO:0003684;damaged DNA binding;1.10731747215629e-05!GO:0007093;mitotic cell cycle checkpoint;1.23820846059677e-05!GO:0006613;cotranslational protein targeting to membrane;1.26535187894626e-05!GO:0008168;methyltransferase activity;1.29826053250969e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.42487878865419e-05!GO:0031072;heat shock protein binding;1.5346676832194e-05!GO:0043066;negative regulation of apoptosis;1.57497248943202e-05!GO:0005798;Golgi-associated vesicle;1.97162869458109e-05!GO:0003678;DNA helicase activity;2.11693969003999e-05!GO:0043065;positive regulation of apoptosis;2.25561367246855e-05!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;2.29167390477811e-05!GO:0003677;DNA binding;2.47662680411436e-05!GO:0005762;mitochondrial large ribosomal subunit;2.53066627236015e-05!GO:0000315;organellar large ribosomal subunit;2.53066627236015e-05!GO:0031326;regulation of cellular biosynthetic process;2.55572466746314e-05!GO:0032774;RNA biosynthetic process;2.74414801310739e-05!GO:0004518;nuclease activity;2.87948516298883e-05!GO:0008186;RNA-dependent ATPase activity;2.95724281207294e-05!GO:0065009;regulation of a molecular function;2.9989632777944e-05!GO:0043068;positive regulation of programmed cell death;3.33111712409608e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;3.62989064940079e-05!GO:0006916;anti-apoptosis;3.63341575194071e-05!GO:0005768;endosome;3.69828141395054e-05!GO:0006351;transcription, DNA-dependent;3.89917085151621e-05!GO:0003682;chromatin binding;3.90742647614213e-05!GO:0009165;nucleotide biosynthetic process;4.05363008859007e-05!GO:0016564;transcription repressor activity;4.17606940234159e-05!GO:0006401;RNA catabolic process;4.43319453796581e-05!GO:0051427;hormone receptor binding;4.46250930402355e-05!GO:0043021;ribonucleoprotein binding;5.26082905106954e-05!GO:0016363;nuclear matrix;5.3561953703521e-05!GO:0048523;negative regulation of cellular process;5.57962527297781e-05!GO:0000314;organellar small ribosomal subunit;6.65920671235039e-05!GO:0005763;mitochondrial small ribosomal subunit;6.65920671235039e-05!GO:0006402;mRNA catabolic process;6.69836590720732e-05!GO:0007052;mitotic spindle organization and biogenesis;6.78976277027108e-05!GO:0045786;negative regulation of progression through cell cycle;7.82379239235814e-05!GO:0006270;DNA replication initiation;7.8307720410583e-05!GO:0006626;protein targeting to mitochondrion;8.35803059613049e-05!GO:0007006;mitochondrial membrane organization and biogenesis;8.50383783809252e-05!GO:0035257;nuclear hormone receptor binding;8.6418066316569e-05!GO:0003729;mRNA binding;8.6418066316569e-05!GO:0006612;protein targeting to membrane;9.21803710733602e-05!GO:0004004;ATP-dependent RNA helicase activity;9.25846165659606e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;9.27910013385759e-05!GO:0006414;translational elongation;9.34653129844954e-05!GO:0009892;negative regulation of metabolic process;9.69835743278113e-05!GO:0000228;nuclear chromosome;9.71209171711408e-05!GO:0043681;protein import into mitochondrion;9.97648463708341e-05!GO:0006284;base-excision repair;0.000107078536982752!GO:0005770;late endosome;0.000113732435054406!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000130738948558694!GO:0030658;transport vesicle membrane;0.000139486567343181!GO:0006352;transcription initiation;0.000141984146674472!GO:0030880;RNA polymerase complex;0.000145641062283634!GO:0045449;regulation of transcription;0.000147221390559938!GO:0009889;regulation of biosynthetic process;0.000165981320280373!GO:0004674;protein serine/threonine kinase activity;0.00021049289923758!GO:0046483;heterocycle metabolic process;0.00021064499602695!GO:0006520;amino acid metabolic process;0.000217706835684785!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000218675093997935!GO:0015399;primary active transmembrane transporter activity;0.000218675093997935!GO:0006383;transcription from RNA polymerase III promoter;0.000218675093997935!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000218709440419043!GO:0019752;carboxylic acid metabolic process;0.000228884845005945!GO:0006917;induction of apoptosis;0.000233860550619487!GO:0007243;protein kinase cascade;0.000241125919189099!GO:0003711;transcription elongation regulator activity;0.000243295158965875!GO:0000786;nucleosome;0.000247102945056536!GO:0042770;DNA damage response, signal transduction;0.000260656442912102!GO:0016491;oxidoreductase activity;0.000262135378936563!GO:0016126;sterol biosynthetic process;0.000263120637412047!GO:0019867;outer membrane;0.000266026267916857!GO:0006082;organic acid metabolic process;0.000269668266670386!GO:0031968;organelle outer membrane;0.000275669594582273!GO:0006091;generation of precursor metabolites and energy;0.000292728071501003!GO:0005885;Arp2/3 protein complex;0.000292802798870831!GO:0000922;spindle pole;0.000293812108943496!GO:0015631;tubulin binding;0.000295156188672936!GO:0016481;negative regulation of transcription;0.000300964426272966!GO:0000819;sister chromatid segregation;0.000307155267668777!GO:0012502;induction of programmed cell death;0.000326923425707485!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000336065243043214!GO:0000428;DNA-directed RNA polymerase complex;0.000336065243043214!GO:0008408;3'-5' exonuclease activity;0.00033724069054138!GO:0006405;RNA export from nucleus;0.000363631852019509!GO:0000070;mitotic sister chromatid segregation;0.000375069983407095!GO:0005741;mitochondrial outer membrane;0.000377991791793785!GO:0007017;microtubule-based process;0.000385661089117143!GO:0030660;Golgi-associated vesicle membrane;0.000451348084125513!GO:0008632;apoptotic program;0.000451348084125513!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000455075915331524!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000476085935751932!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000484931270182977!GO:0044431;Golgi apparatus part;0.000486695485387435!GO:0003924;GTPase activity;0.000487049169151307!GO:0032508;DNA duplex unwinding;0.000500968845977541!GO:0032392;DNA geometric change;0.000500968845977541!GO:0048522;positive regulation of cellular process;0.000502885832009687!GO:0051252;regulation of RNA metabolic process;0.00051071719291094!GO:0005758;mitochondrial intermembrane space;0.000532462126459256!GO:0016859;cis-trans isomerase activity;0.000550899508975027!GO:0045454;cell redox homeostasis;0.000555640961095655!GO:0003714;transcription corepressor activity;0.000571509145564599!GO:0048519;negative regulation of biological process;0.000582088228482624!GO:0000082;G1/S transition of mitotic cell cycle;0.000633502621603608!GO:0006818;hydrogen transport;0.000635527242843848!GO:0043596;nuclear replication fork;0.000654738309774096!GO:0016251;general RNA polymerase II transcription factor activity;0.000665448836291907!GO:0006338;chromatin remodeling;0.000675270557272679!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.000704784911317696!GO:0006268;DNA unwinding during replication;0.000712134026566693!GO:0006275;regulation of DNA replication;0.000752024409522099!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.000802337667730847!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000842770204518387!GO:0019783;small conjugating protein-specific protease activity;0.000875484123426977!GO:0004532;exoribonuclease activity;0.000897483621339729!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.000897483621339729!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000942962137851789!GO:0044440;endosomal part;0.000953404143831296!GO:0010008;endosome membrane;0.000953404143831296!GO:0015992;proton transport;0.000993860253467386!GO:0048471;perinuclear region of cytoplasm;0.000994418331164671!GO:0042393;histone binding;0.00100128576798484!GO:0009112;nucleobase metabolic process;0.00100365200124797!GO:0008654;phospholipid biosynthetic process;0.00102998241365541!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00103677574430662!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00103677574430662!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00103677574430662!GO:0006289;nucleotide-excision repair;0.00105329180758752!GO:0005876;spindle microtubule;0.00106852910574318!GO:0031570;DNA integrity checkpoint;0.0011188258775331!GO:0004843;ubiquitin-specific protease activity;0.00114786654115449!GO:0031124;mRNA 3'-end processing;0.00115845237244285!GO:0030384;phosphoinositide metabolic process;0.00119109080947868!GO:0030521;androgen receptor signaling pathway;0.00119379081548096!GO:0005684;U2-dependent spliceosome;0.0012479052128738!GO:0000059;protein import into nucleus, docking;0.00125527215024385!GO:0006695;cholesterol biosynthetic process;0.00128024834769028!GO:0031123;RNA 3'-end processing;0.0013245774028049!GO:0008234;cysteine-type peptidase activity;0.00135020300238956!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00147668479657714!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00152485318445067!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00152485318445067!GO:0006144;purine base metabolic process;0.00155144317590951!GO:0000049;tRNA binding;0.00159355692994173!GO:0046489;phosphoinositide biosynthetic process;0.0016026803970871!GO:0004221;ubiquitin thiolesterase activity;0.00163061636549911!GO:0005669;transcription factor TFIID complex;0.00163061636549911!GO:0005048;signal sequence binding;0.00164133025458814!GO:0022890;inorganic cation transmembrane transporter activity;0.00167505297224689!GO:0009124;nucleoside monophosphate biosynthetic process;0.00169434237704991!GO:0009123;nucleoside monophosphate metabolic process;0.00169434237704991!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.00169434237704991!GO:0046474;glycerophospholipid biosynthetic process;0.00172921630262683!GO:0048500;signal recognition particle;0.00177636723580263!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00181971194872797!GO:0044438;microbody part;0.0018443696399574!GO:0044439;peroxisomal part;0.0018443696399574!GO:0032200;telomere organization and biogenesis;0.0018568545389979!GO:0000723;telomere maintenance;0.0018568545389979!GO:0008270;zinc ion binding;0.00198297067394478!GO:0043492;ATPase activity, coupled to movement of substances;0.0019996550787548!GO:0006355;regulation of transcription, DNA-dependent;0.0020163059533188!GO:0051053;negative regulation of DNA metabolic process;0.0020163059533188!GO:0004003;ATP-dependent DNA helicase activity;0.00202095171080362!GO:0006891;intra-Golgi vesicle-mediated transport;0.00211357258490863!GO:0043601;nuclear replisome;0.00223911772714129!GO:0030894;replisome;0.00223911772714129!GO:0016197;endosome transport;0.00230256718178872!GO:0031970;organelle envelope lumen;0.00239366702243152!GO:0047485;protein N-terminus binding;0.00239366702243152!GO:0005637;nuclear inner membrane;0.0024071891990598!GO:0008312;7S RNA binding;0.00241176614359266!GO:0008139;nuclear localization sequence binding;0.00252396747734734!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00255416084617416!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00256257016970393!GO:0051920;peroxiredoxin activity;0.0026211810892172!GO:0016790;thiolester hydrolase activity;0.0026211810892172!GO:0000287;magnesium ion binding;0.00264470286472597!GO:0006650;glycerophospholipid metabolic process;0.00268566917725162!GO:0005525;GTP binding;0.00272211576383326!GO:0031903;microbody membrane;0.00276432519020633!GO:0005778;peroxisomal membrane;0.00276432519020633!GO:0045941;positive regulation of transcription;0.00279916465615375!GO:0008022;protein C-terminus binding;0.00281035672324598!GO:0000178;exosome (RNase complex);0.00283755034515869!GO:0032259;methylation;0.00289528726624546!GO:0009451;RNA modification;0.00293124726056374!GO:0044454;nuclear chromosome part;0.00301554294162289!GO:0009161;ribonucleoside monophosphate metabolic process;0.00308765902800186!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.00308765902800186!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00308765902800186!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00313155826572744!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00319234368819024!GO:0006611;protein export from nucleus;0.00319234368819024!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00340638688954805!GO:0003887;DNA-directed DNA polymerase activity;0.00347171372083864!GO:0043488;regulation of mRNA stability;0.00350638630385128!GO:0043487;regulation of RNA stability;0.00350638630385128!GO:0016853;isomerase activity;0.00350919872892247!GO:0030663;COPI coated vesicle membrane;0.0035496474282876!GO:0030126;COPI vesicle coat;0.0035496474282876!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0035496474282876!GO:0043414;biopolymer methylation;0.00368720339987829!GO:0050790;regulation of catalytic activity;0.00377777271201534!GO:0035258;steroid hormone receptor binding;0.00386391884728128!GO:0044450;microtubule organizing center part;0.00403467776060235!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00416310809153179!GO:0045047;protein targeting to ER;0.00416310809153179!GO:0033116;ER-Golgi intermediate compartment membrane;0.00426673124699056!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00426673124699056!GO:0030118;clathrin coat;0.00428189101595964!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00435179163839596!GO:0000726;non-recombinational repair;0.00443615408927312!GO:0000152;nuclear ubiquitin ligase complex;0.00463558741179031!GO:0000077;DNA damage checkpoint;0.0046678535632474!GO:0015980;energy derivation by oxidation of organic compounds;0.00479633232071342!GO:0051539;4 iron, 4 sulfur cluster binding;0.00479633232071342!GO:0008017;microtubule binding;0.00495065307210834!GO:0000793;condensed chromosome;0.00501684028788329!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00503641508476778!GO:0051540;metal cluster binding;0.00519979007966931!GO:0051536;iron-sulfur cluster binding;0.00519979007966931!GO:0009116;nucleoside metabolic process;0.00530607966846301!GO:0008180;signalosome;0.00534519467069455!GO:0000725;recombinational repair;0.00546405037220492!GO:0000724;double-strand break repair via homologous recombination;0.00546405037220492!GO:0030518;steroid hormone receptor signaling pathway;0.00547430387744197!GO:0006400;tRNA modification;0.00550429721066959!GO:0008287;protein serine/threonine phosphatase complex;0.00558780559098016!GO:0042613;MHC class II protein complex;0.00559138722370279!GO:0006368;RNA elongation from RNA polymerase II promoter;0.00568428682144975!GO:0004536;deoxyribonuclease activity;0.00575196521350964!GO:0046966;thyroid hormone receptor binding;0.00576535400454695!GO:0005874;microtubule;0.00580456704445692!GO:0031902;late endosome membrane;0.00592301509157509!GO:0030134;ER to Golgi transport vesicle;0.00607501375001034!GO:0045893;positive regulation of transcription, DNA-dependent;0.00613420882347876!GO:0051087;chaperone binding;0.00619305953952787!GO:0006595;polyamine metabolic process;0.00631757538933853!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00632044970973514!GO:0008276;protein methyltransferase activity;0.00632850684789571!GO:0006519;amino acid and derivative metabolic process;0.00635342641889974!GO:0000175;3'-5'-exoribonuclease activity;0.00637930466458366!GO:0030127;COPII vesicle coat;0.00637930466458366!GO:0012507;ER to Golgi transport vesicle membrane;0.00637930466458366!GO:0005769;early endosome;0.00638813429282714!GO:0007010;cytoskeleton organization and biogenesis;0.00672942766283557!GO:0051320;S phase;0.00693227301381356!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.00697354214032017!GO:0030125;clathrin vesicle coat;0.00716168277433697!GO:0030665;clathrin coated vesicle membrane;0.00716168277433697!GO:0043022;ribosome binding;0.00733206971942351!GO:0030137;COPI-coated vesicle;0.00733206971942351!GO:0051789;response to protein stimulus;0.00747344369255071!GO:0006986;response to unfolded protein;0.00747344369255071!GO:0046822;regulation of nucleocytoplasmic transport;0.00749789358087825!GO:0030133;transport vesicle;0.00752725372082666!GO:0000139;Golgi membrane;0.00762729664751308!GO:0065007;biological regulation;0.00765858861688635!GO:0005777;peroxisome;0.00765858861688635!GO:0042579;microbody;0.00765858861688635!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00776033255438644!GO:0015002;heme-copper terminal oxidase activity;0.00776033255438644!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00776033255438644!GO:0004129;cytochrome-c oxidase activity;0.00776033255438644!GO:0004722;protein serine/threonine phosphatase activity;0.0078143755775184!GO:0031577;spindle checkpoint;0.00782678934542043!GO:0006301;postreplication repair;0.00790690670638698!GO:0046914;transition metal ion binding;0.00790690670638698!GO:0016584;nucleosome positioning;0.00819391306430326!GO:0006378;mRNA polyadenylation;0.00826145358668362!GO:0035267;NuA4 histone acetyltransferase complex;0.00895516281281967!GO:0005832;chaperonin-containing T-complex;0.00896005402124883!GO:0000339;RNA cap binding;0.00908040258495471!GO:0000781;chromosome, telomeric region;0.00912996206735028!GO:0000792;heterochromatin;0.00942704701076418!GO:0030433;ER-associated protein catabolic process;0.00943019834852652!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.00943019834852652!GO:0008159;positive transcription elongation factor activity;0.0097109377121583!GO:0003746;translation elongation factor activity;0.00977126173743781!GO:0006541;glutamine metabolic process;0.0102760008342052!GO:0006376;mRNA splice site selection;0.0103777544277307!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0103777544277307!GO:0009967;positive regulation of signal transduction;0.0104888549389842!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0105845545690484!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0105845545690484!GO:0009126;purine nucleoside monophosphate metabolic process;0.0105845545690484!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0105845545690484!GO:0008156;negative regulation of DNA replication;0.0107553853369262!GO:0008610;lipid biosynthetic process;0.0107735377183379!GO:0051223;regulation of protein transport;0.011101629794014!GO:0006950;response to stress;0.0113729900875016!GO:0042113;B cell activation;0.0113729900875016!GO:0046112;nucleobase biosynthetic process;0.0115266982959037!GO:0043189;H4/H2A histone acetyltransferase complex;0.0121261732445515!GO:0007346;regulation of progression through mitotic cell cycle;0.0121909034599176!GO:0042802;identical protein binding;0.0124293220029142!GO:0005663;DNA replication factor C complex;0.0126095966311933!GO:0004520;endodeoxyribonuclease activity;0.0134874892224177!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.0137378011351011!GO:0032561;guanyl ribonucleotide binding;0.0137586474134904!GO:0019001;guanyl nucleotide binding;0.0137586474134904!GO:0004448;isocitrate dehydrogenase activity;0.0137983457393978!GO:0000118;histone deacetylase complex;0.0138518745657609!GO:0050662;coenzyme binding;0.0139692866560033!GO:0006220;pyrimidine nucleotide metabolic process;0.0140997062292716!GO:0005773;vacuole;0.014225137526271!GO:0031252;leading edge;0.0143016862955425!GO:0000323;lytic vacuole;0.0143893486298109!GO:0005764;lysosome;0.0143893486298109!GO:0005788;endoplasmic reticulum lumen;0.0146162281688574!GO:0030867;rough endoplasmic reticulum membrane;0.0146162281688574!GO:0045892;negative regulation of transcription, DNA-dependent;0.0147328185104024!GO:0006406;mRNA export from nucleus;0.0149016339655595!GO:0051090;regulation of transcription factor activity;0.0154860401437962!GO:0008538;proteasome activator activity;0.0155111520704058!GO:0016272;prefoldin complex;0.0156302804465155!GO:0043621;protein self-association;0.0157308730769265!GO:0000123;histone acetyltransferase complex;0.0158153711730871!GO:0006506;GPI anchor biosynthetic process;0.0162218378003809!GO:0016408;C-acyltransferase activity;0.0162405443168196!GO:0000209;protein polyubiquitination;0.0164173476869395!GO:0009615;response to virus;0.016656167971696!GO:0043631;RNA polyadenylation;0.0168021115607795!GO:0050681;androgen receptor binding;0.0168639449455628!GO:0006607;NLS-bearing substrate import into nucleus;0.0169286716840882!GO:0007264;small GTPase mediated signal transduction;0.017054605204493!GO:0008097;5S rRNA binding;0.0172942744140473!GO:0016407;acetyltransferase activity;0.0176974326800817!GO:0031625;ubiquitin protein ligase binding;0.0177682515871525!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0183841236782808!GO:0045039;protein import into mitochondrial inner membrane;0.0183841236782808!GO:0006730;one-carbon compound metabolic process;0.0185889070673451!GO:0043284;biopolymer biosynthetic process;0.0189171874761552!GO:0003725;double-stranded RNA binding;0.0194612897690346!GO:0005658;alpha DNA polymerase:primase complex;0.0194612897690346!GO:0000096;sulfur amino acid metabolic process;0.019572456907275!GO:0022406;membrane docking;0.0196274938833019!GO:0048278;vesicle docking;0.0196274938833019!GO:0019843;rRNA binding;0.0196391828518235!GO:0009893;positive regulation of metabolic process;0.0196410809945993!GO:0046467;membrane lipid biosynthetic process;0.0196504200775661!GO:0051098;regulation of binding;0.0197360248186704!GO:0005774;vacuolar membrane;0.0198685501598803!GO:0008652;amino acid biosynthetic process;0.0199106048590169!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.020170600330312!GO:0022411;cellular component disassembly;0.0203763079412607!GO:0006505;GPI anchor metabolic process;0.0209583578613987!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0209583578613987!GO:0004540;ribonuclease activity;0.0211875675551205!GO:0019904;protein domain specific binding;0.0212485529434475!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0213414581645486!GO:0051059;NF-kappaB binding;0.0217943872562331!GO:0006740;NADPH regeneration;0.0219296045152474!GO:0006098;pentose-phosphate shunt;0.0219296045152474!GO:0030130;clathrin coat of trans-Golgi network vesicle;0.0219296045152474!GO:0012510;trans-Golgi network transport vesicle membrane;0.0219296045152474!GO:0031325;positive regulation of cellular metabolic process;0.0219490432639429!GO:0006778;porphyrin metabolic process;0.0224485693056592!GO:0033013;tetrapyrrole metabolic process;0.0224485693056592!GO:0006303;double-strand break repair via nonhomologous end joining;0.022505399768055!GO:0007004;telomere maintenance via telomerase;0.022505399768055!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0226593738544962!GO:0015036;disulfide oxidoreductase activity;0.0232842812501282!GO:0006354;RNA elongation;0.0234330803671033!GO:0009303;rRNA transcription;0.0234330803671033!GO:0000910;cytokinesis;0.0239514251379479!GO:0051092;activation of NF-kappaB transcription factor;0.0240050121329963!GO:0007242;intracellular signaling cascade;0.0240606243007074!GO:0043624;cellular protein complex disassembly;0.0240934153066026!GO:0032404;mismatch repair complex binding;0.0244465163691214!GO:0048518;positive regulation of biological process;0.0244599022455887!GO:0032039;integrator complex;0.0246231249357343!GO:0030119;AP-type membrane coat adaptor complex;0.0248460399980593!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0254952900159793!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0254952900159793!GO:0031982;vesicle;0.0255088040139592!GO:0030522;intracellular receptor-mediated signaling pathway;0.0256402290862632!GO:0007021;tubulin folding;0.0256440900064501!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.026138463354705!GO:0030508;thiol-disulfide exchange intermediate activity;0.0264916845722372!GO:0016605;PML body;0.0265186709863069!GO:0019238;cyclohydrolase activity;0.0267544033580659!GO:0006904;vesicle docking during exocytosis;0.0271022083374044!GO:0031988;membrane-bound vesicle;0.0276692836970247!GO:0008299;isoprenoid biosynthetic process;0.0277743258788078!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0279042588634513!GO:0005092;GDP-dissociation inhibitor activity;0.0281196424312903!GO:0051640;organelle localization;0.0284407483417864!GO:0005784;translocon complex;0.0285064335796985!GO:0007265;Ras protein signal transduction;0.0288114774912799!GO:0006007;glucose catabolic process;0.0289016029822065!GO:0003985;acetyl-CoA C-acetyltransferase activity;0.0291246785573965!GO:0030174;regulation of DNA replication initiation;0.0291520685577336!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.0291520685577336!GO:0046128;purine ribonucleoside metabolic process;0.0296112982868413!GO:0042278;purine nucleoside metabolic process;0.0296112982868413!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0296269009311472!GO:0010257;NADH dehydrogenase complex assembly;0.0296269009311472!GO:0033108;mitochondrial respiratory chain complex assembly;0.0296269009311472!GO:0032405;MutLalpha complex binding;0.0305732147754738!GO:0051287;NAD binding;0.0307425420839874!GO:0032984;macromolecular complex disassembly;0.0309661764061354!GO:0006779;porphyrin biosynthetic process;0.0310445122136706!GO:0033014;tetrapyrrole biosynthetic process;0.0310445122136706!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0312705655497531!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0313982942895692!GO:0050851;antigen receptor-mediated signaling pathway;0.0314696613062221!GO:0030695;GTPase regulator activity;0.0316000606744516!GO:0051297;centrosome organization and biogenesis;0.0321384737155268!GO:0031023;microtubule organizing center organization and biogenesis;0.0321384737155268!GO:0005869;dynactin complex;0.033167803544801!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0331789384340143!GO:0004576;oligosaccharyl transferase activity;0.0331814215258482!GO:0006266;DNA ligation;0.0335462460258272!GO:0033673;negative regulation of kinase activity;0.0335462460258272!GO:0006469;negative regulation of protein kinase activity;0.0335462460258272!GO:0006497;protein amino acid lipidation;0.0336881158363484!GO:0008537;proteasome activator complex;0.0336881158363484!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.034213261794664!GO:0016453;C-acetyltransferase activity;0.034213261794664!GO:0045045;secretory pathway;0.0343447045874715!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0349171676618679!GO:0001891;phagocytic cup;0.0349723728950821!GO:0006596;polyamine biosynthetic process;0.0351027268999439!GO:0030131;clathrin adaptor complex;0.0351185655634089!GO:0046633;alpha-beta T cell proliferation;0.0352009168916635!GO:0006278;RNA-dependent DNA replication;0.0353067414805929!GO:0044437;vacuolar part;0.0358587340361092!GO:0051348;negative regulation of transferase activity;0.0358587340361092!GO:0051656;establishment of organelle localization;0.0362247933826098!GO:0048487;beta-tubulin binding;0.0362247933826098!GO:0005765;lysosomal membrane;0.0362927161124899!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0363229723900334!GO:0005680;anaphase-promoting complex;0.0373983229574963!GO:0006118;electron transport;0.037770297628417!GO:0009113;purine base biosynthetic process;0.0377868161987903!GO:0004215;cathepsin H activity;0.0379872562993699!GO:0046426;negative regulation of JAK-STAT cascade;0.0379872562993699!GO:0009396;folic acid and derivative biosynthetic process;0.0381457483564985!GO:0007050;cell cycle arrest;0.0382060938574869!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0382060938574869!GO:0018193;peptidyl-amino acid modification;0.0383493093369509!GO:0009067;aspartate family amino acid biosynthetic process;0.0384510272958843!GO:0005754;mitochondrial proton-transporting ATP synthase, catalytic core;0.0386236567232042!GO:0000275;mitochondrial proton-transporting ATP synthase complex, catalytic core F(1);0.0386236567232042!GO:0045267;proton-transporting ATP synthase, catalytic core;0.0386236567232042!GO:0031647;regulation of protein stability;0.0392111239194337!GO:0016884;carbon-nitrogen ligase activity, with glutamine as amido-N-donor;0.0393823959543824!GO:0008320;protein transmembrane transporter activity;0.0401093953660254!GO:0019104;DNA N-glycosylase activity;0.0403509091147116!GO:0045815;positive regulation of gene expression, epigenetic;0.0407887415050699!GO:0000387;spliceosomal snRNP biogenesis;0.0408599450408831!GO:0042054;histone methyltransferase activity;0.0409009541206058!GO:0030258;lipid modification;0.0409224822630141!GO:0030145;manganese ion binding;0.0409874568424037!GO:0000738;DNA catabolic process, exonucleolytic;0.0410472072127852!GO:0006379;mRNA cleavage;0.0412402414674415!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0412793537343361!GO:0043697;cell dedifferentiation;0.041676329507329!GO:0043696;dedifferentiation;0.041676329507329!GO:0003702;RNA polymerase II transcription factor activity;0.042044479810551!GO:0046519;sphingoid metabolic process;0.0421955189124892!GO:0033261;regulation of progression through S phase;0.0422136237354858!GO:0042026;protein refolding;0.0423941967441524!GO:0019814;immunoglobulin complex;0.0430672336414978!GO:0019815;B cell receptor complex;0.0430672336414978!GO:0005851;eukaryotic translation initiation factor 2B complex;0.0431642955643964!GO:0016944;RNA polymerase II transcription elongation factor activity;0.0432224045488475!GO:0008637;apoptotic mitochondrial changes;0.0432855334955916!GO:0033170;DNA-protein loading ATPase activity;0.0432855334955916!GO:0003689;DNA clamp loader activity;0.0432855334955916!GO:0006672;ceramide metabolic process;0.0432855334955916!GO:0050871;positive regulation of B cell activation;0.043391984775222!GO:0017134;fibroblast growth factor binding;0.0436970802722684!GO:0000790;nuclear chromatin;0.044154576226544!GO:0008250;oligosaccharyl transferase complex;0.044154576226544!GO:0022415;viral reproductive process;0.044154576226544!GO:0009066;aspartate family amino acid metabolic process;0.044154576226544!GO:0004239;methionyl aminopeptidase activity;0.0442459204548622!GO:0045120;pronucleus;0.044284801944197!GO:0004428;inositol or phosphatidylinositol kinase activity;0.045815825866945!GO:0016569;covalent chromatin modification;0.0466686153268452!GO:0008536;Ran GTPase binding;0.0468626953060792!GO:0008213;protein amino acid alkylation;0.0472429726434651!GO:0006479;protein amino acid methylation;0.0472429726434651!GO:0051338;regulation of transferase activity;0.0473382816201633!GO:0009081;branched chain family amino acid metabolic process;0.0478673449034074!GO:0000930;gamma-tubulin complex;0.0487545708639967!GO:0022884;macromolecule transmembrane transporter activity;0.0493456046460588!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0493456046460588!GO:0051318;G1 phase;0.0499797952990946 | |||
|sample_id=10775 | |||
|sample_note= | |||
|sample_sex=female | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=POU5F1:3.18856068881;POU2F1..3:3.1411673349;PDX1:2.22820804656;VSX1,2:2.13344885907;E2F1..5:2.0224762921;PAX6:1.88623668214;AIRE:1.84546550935;YY1:1.68578282868;MYB:1.61315443819;FOXA2:1.59206466145;NFY{A,B,C}:1.56498865045;ELK1,4_GABP{A,B1}:1.49239044616;OCT4_SOX2{dimer}:1.45687407748;ELF1,2,4:1.38207612015;NKX2-1,4:1.22996352229;BREu{core}:1.20317764813;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.16484688084;DMAP1_NCOR{1,2}_SMARC:1.10579668615;HOXA9_MEIS1:1.10431605804;FOXP3:1.04964132736;NFKB1_REL_RELA:0.922603006486;ZEB1:0.911044286827;CDC5L:0.875342942276;SNAI1..3:0.796308909779;GFI1:0.757396718092;NRF1:0.748856528851;SPI1:0.733025304002;CUX2:0.721039028289;RUNX1..3:0.711025879467;ZNF143:0.707015654804;TFDP1:0.663777643932;EVI1:0.663734641533;MYOD1:0.645618445815;RFX2..5_RFXANK_RFXAP:0.579776830456;FOX{I1,J2}:0.524391878889;FOXP1:0.521657222088;NKX6-1,2:0.512659015133;SPIB:0.512401721611;HOX{A5,B5}:0.484364168728;FOX{F1,F2,J1}:0.451529715271;FOXN1:0.44594797241;GATA6:0.441472084483;NR6A1:0.439420268473;TGIF1:0.431847801995;PBX1:0.426781684071;PITX1..3:0.42189176857;IRF1,2:0.38762008802;LMO2:0.380237308237;AHR_ARNT_ARNT2:0.335756495706;SOX{8,9,10}:0.322832532183;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.322112575742;bHLH_family:0.321942944379;PAX3,7:0.315261901083;TOPORS:0.30514492567;DBP:0.298483759933;NKX2-2,8:0.296308725261;POU1F1:0.2897632848;ALX1:0.254326935515;NANOG:0.251018123501;SPZ1:0.235320524744;BPTF:0.205816562985;ETS1,2:0.201868574599;SOX5:0.198739255155;STAT5{A,B}:0.180497420316;FOXQ1:0.178003908388;CDX1,2,4:0.173377213752;NANOG{mouse}:0.162007362827;HOX{A4,D4}:0.148348694713;PAX4:0.127935444697;HES1:0.12748697165;ATF5_CREB3:0.125049255812;NR5A1,2:0.10298716614;PAX8:0.0832571641287;EN1,2:0.069535757234;ZBTB16:0.0568692322668;HNF4A_NR2F1,2:-0.0211143575518;ESRRA:-0.0290446432537;ADNP_IRX_SIX_ZHX:-0.0548203146988;IKZF2:-0.0956332183782;SOX17:-0.103315049039;IRF7:-0.110312116278;PRRX1,2:-0.110432853177;TEF:-0.115012122361;IKZF1:-0.118621612166;HAND1,2:-0.123279302032;EBF1:-0.126083854326;ATF4:-0.142809542416;NKX3-2:-0.171376706534;HSF1,2:-0.193336028111;PAX1,9:-0.193912862211;STAT1,3:-0.230402197617;NFIX:-0.263486376351;PAX2:-0.265270058784;HOX{A6,A7,B6,B7}:-0.300938641475;MYFfamily:-0.310856530939;TLX2:-0.315563201289;HNF1A:-0.318700857832;AR:-0.337361010007;ZNF384:-0.38616884898;ZNF148:-0.393963228635;LEF1_TCF7_TCF7L1,2:-0.420833408063;PPARG:-0.423874253094;RXRA_VDR{dimer}:-0.432939736436;NFIL3:-0.451947071376;ESR1:-0.454207919894;RBPJ:-0.461251591749;RORA:-0.475184374693;FOXM1:-0.480392492391;MEF2{A,B,C,D}:-0.483429025204;LHX3,4:-0.493769964978;ARID5B:-0.53029860226;NKX2-3_NKX2-5:-0.544582595821;ZFP161:-0.548969138644;MYBL2:-0.558077556005;FOXO1,3,4:-0.567019682929;NFE2L1:-0.570748207328;NFATC1..3:-0.571695605584;UFEwm:-0.59104377118;FOX{D1,D2}:-0.613089330216;POU3F1..4:-0.625633222138;HBP1_HMGB_SSRP1_UBTF:-0.655596866953;FOSL2:-0.657132895128;GCM1,2:-0.671454387746;FOS_FOS{B,L1}_JUN{B,D}:-0.680818175752;NKX3-1:-0.685129250471;CRX:-0.692027650974;ALX4:-0.695913889984;FOXD3:-0.731539452083;PRDM1:-0.731776880751;BACH2:-0.73607917819;MAFB:-0.746437709574;TP53:-0.749794352545;SREBF1,2:-0.774216648796;KLF4:-0.806203041294;MTE{core}:-0.810626923902;CEBPA,B_DDIT3:-0.814325005216;HMX1:-0.815761705827;ONECUT1,2:-0.818054022259;MED-1{core}:-0.825973460953;NR1H4:-0.843079812294;RFX1:-0.843178427414;HIC1:-0.851235024374;GFI1B:-0.854624959442;NFE2:-0.856312641598;ATF2:-0.869017936219;GATA4:-0.891228560156;ZNF238:-0.892605893875;SMAD1..7,9:-0.895036851122;GZF1:-0.900796437666;CREB1:-0.907312115383;JUN:-0.930306580162;SRF:-0.968263851242;HIF1A:-0.995326612207;XBP1:-1.00763665819;FOXL1:-1.02370115688;ATF6:-1.04334269009;ZIC1..3:-1.05739027754;NHLH1,2:-1.06094276773;TFAP4:-1.06506636629;SOX2:-1.07246895056;HLF:-1.07653100987;ZNF423:-1.08634379111;MTF1:-1.0880749996;REST:-1.1115898177;TAL1_TCF{3,4,12}:-1.12011488853;GLI1..3:-1.12525546201;EGR1..3:-1.19155283037;POU6F1:-1.20667525893;STAT2,4,6:-1.25975539657;RREB1:-1.27355249929;NFE2L2:-1.28046992279;TBP:-1.2839409114;TFAP2B:-1.28737735442;MZF1:-1.28981340716;RXR{A,B,G}:-1.43024745446;TBX4,5:-1.44428505358;SP1:-1.47131464248;TEAD1:-1.47164325615;HMGA1,2:-1.53197186078;TFCP2:-1.53658992931;GTF2I:-1.54100658917;ZBTB6:-1.61374985855;MAZ:-1.63293771455;EP300:-1.63709129255;NR3C1:-1.64574897049;XCPE1{core}:-1.65398319187;TFAP2{A,C}:-1.72833020869;GTF2A1,2:-1.76203578861;T:-1.7968292437;PATZ1:-1.93677597555;PAX5:-1.94291092799;TLX1..3_NFIC{dimer}:-2.04066501916 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10775-110G1;search_select_hide=table117:FF:10775-110G1 | |||
}} | }} |
Latest revision as of 15:03, 3 June 2020
Name: | lymphoma, malignant, hairy B-cell cell line:MLMA |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11935 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11935
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11935
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.139 |
10 | 10 | 0.0253 |
100 | 100 | 0.607 |
101 | 101 | 0.244 |
102 | 102 | 0.435 |
103 | 103 | 0.563 |
104 | 104 | 0.486 |
105 | 105 | 0.746 |
106 | 106 | 0.811 |
107 | 107 | 0.745 |
108 | 108 | 0.794 |
109 | 109 | 0.244 |
11 | 11 | 0.269 |
110 | 110 | 0.511 |
111 | 111 | 0.111 |
112 | 112 | 0.717 |
113 | 113 | 0.617 |
114 | 114 | 0.939 |
115 | 115 | 0.749 |
116 | 116 | 0.553 |
117 | 117 | 0.014 |
118 | 118 | 0.475 |
119 | 119 | 0.364 |
12 | 12 | 0.697 |
120 | 120 | 0.444 |
121 | 121 | 0.39 |
122 | 122 | 0.326 |
123 | 123 | 0.0431 |
124 | 124 | 0.173 |
125 | 125 | 0.224 |
126 | 126 | 0.509 |
127 | 127 | 0.799 |
128 | 128 | 0.525 |
129 | 129 | 0.543 |
13 | 13 | 0.158 |
130 | 130 | 0.494 |
131 | 131 | 0.169 |
132 | 132 | 0.0975 |
133 | 133 | 0.958 |
134 | 134 | 0.713 |
135 | 135 | 0.943 |
136 | 136 | 0.0409 |
137 | 137 | 0.458 |
138 | 138 | 0.979 |
139 | 139 | 0.399 |
14 | 14 | 0.787 |
140 | 140 | 0.692 |
141 | 141 | 0.304 |
142 | 142 | 0.562 |
143 | 143 | 0.383 |
144 | 144 | 0.212 |
145 | 145 | 0.103 |
146 | 146 | 0.453 |
147 | 147 | 0.0694 |
148 | 148 | 0.134 |
149 | 149 | 0.346 |
15 | 15 | 0.153 |
150 | 150 | 0.781 |
151 | 151 | 0.636 |
152 | 152 | 0.0709 |
153 | 153 | 0.712 |
154 | 154 | 0.901 |
155 | 155 | 0.0118 |
156 | 156 | 0.655 |
157 | 157 | 0.134 |
158 | 158 | 0.807 |
159 | 159 | 0.243 |
16 | 16 | 0.999 |
160 | 160 | 0.78 |
161 | 161 | 0.314 |
162 | 162 | 0.55 |
163 | 163 | 0.202 |
164 | 164 | 0.502 |
165 | 165 | 0.507 |
166 | 166 | 0.21 |
167 | 167 | 0.172 |
168 | 168 | 0.887 |
169 | 169 | 0.341 |
17 | 17 | 0.761 |
18 | 18 | 0.926 |
19 | 19 | 0.357 |
2 | 2 | 0.32 |
20 | 20 | 0.454 |
21 | 21 | 0.354 |
22 | 22 | 0.493 |
23 | 23 | 0.07 |
24 | 24 | 0.789 |
25 | 25 | 0.0219 |
26 | 26 | 0.157 |
27 | 27 | 0.78 |
28 | 28 | 0.496 |
29 | 29 | 0.0193 |
3 | 3 | 0.271 |
30 | 30 | 0.117 |
31 | 31 | 0.617 |
32 | 32 | 0.209 |
33 | 33 | 0.946 |
34 | 34 | 0.342 |
35 | 35 | 0.317 |
36 | 36 | 0.0668 |
37 | 37 | 0.638 |
38 | 38 | 0.842 |
39 | 39 | 0.439 |
4 | 4 | 0.0311 |
40 | 40 | 0.16 |
41 | 41 | 0.666 |
42 | 42 | 0.135 |
43 | 43 | 0.636 |
44 | 44 | 0.242 |
45 | 45 | 0.423 |
46 | 46 | 0.221 |
47 | 47 | 0.0757 |
48 | 48 | 0.198 |
49 | 49 | 0.135 |
5 | 5 | 0.555 |
50 | 50 | 0.897 |
51 | 51 | 0.929 |
52 | 52 | 0.285 |
53 | 53 | 0.408 |
54 | 54 | 0.564 |
55 | 55 | 0.507 |
56 | 56 | 0.816 |
57 | 57 | 0.303 |
58 | 58 | 0.169 |
59 | 59 | 0.896 |
6 | 6 | 0.866 |
60 | 60 | 0.715 |
61 | 61 | 0.0923 |
62 | 62 | 0.165 |
63 | 63 | 0.814 |
64 | 64 | 0.51 |
65 | 65 | 0.322 |
66 | 66 | 0.0012 |
67 | 67 | 0.974 |
68 | 68 | 0.0573 |
69 | 69 | 0.355 |
7 | 7 | 0.107 |
70 | 70 | 0.354 |
71 | 71 | 0.0344 |
72 | 72 | 0.875 |
73 | 73 | 0.675 |
74 | 74 | 0.913 |
75 | 75 | 0.00283 |
76 | 76 | 0.332 |
77 | 77 | 0.0656 |
78 | 78 | 0.115 |
79 | 79 | 0.556 |
8 | 8 | 0.509 |
80 | 80 | 0.89 |
81 | 81 | 0.0873 |
82 | 82 | 0.433 |
83 | 83 | 0.517 |
84 | 84 | 0.402 |
85 | 85 | 0.0717 |
86 | 86 | 0.426 |
87 | 87 | 0.0415 |
88 | 88 | 0.49 |
89 | 89 | 0.45 |
9 | 9 | 0.556 |
90 | 90 | 6.41817e-4 |
91 | 91 | 0.437 |
92 | 92 | 0.658 |
93 | 93 | 0.707 |
94 | 94 | 0.496 |
95 | 95 | 0.246 |
96 | 96 | 0.656 |
97 | 97 | 0.163 |
98 | 98 | 0.591 |
99 | 99 | 0.385 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11935
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101518 B-lymphoma cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000542 (lymphocyte)
0000219 (motile cell)
0000945 (lymphocyte of B lineage)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0002242 (nucleate cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
0060058 (lymphoma)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100104 (lymphoma cell line sample)
0101518 (B-lymphoma cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000051 (common lymphoid progenitor)