FF:10490-107B4: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005339 | ||
| | |accession_numbers=CAGE;DRX007987;DRR008859;DRZ000284;DRZ001669;DRZ011634;DRZ013019 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002367,UBERON:0005156,UBERON:0004119,UBERON:0000062,UBERON:0004120,UBERON:0000077,UBERON:0000061,UBERON:0000465,UBERON:0000990,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0002530,UBERON:0010147,UBERON:0010317,UBERON:0003937,UBERON:0005399,UBERON:0003101,UBERON:0000079 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0000255 | |||
|ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:7,DOID:305 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100297,FF:0101120,FF:0101019,FF:0101033,FF:0101332 | |||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr14:38064429..38064486,-!p1@FOXA1!1.67!45.27!FOXA1;;chr1:201979743..201979762,+!p1@ELF3!1.62!41.13!ELF3;;chr6:10412600..10412637,-!p1@TFAP2A!1.59!62.29!TFAP2A;;chr11:120107344..120107351,+!p1@POU2F3!1.56!42.79!POU2F3;;chr6:10412392..10412409,-!p4@TFAP2A!1.45!30.73!TFAP2A;;chr5:134369905..134369972,-!p1@PITX1!1.43!39.12!PITX1;;chr1:201979703..201979721,+!p2@ELF3!1.39!23.52!ELF3;;chr6:126240380..126240430,+!p2@NCOA7!1.29!47.51!NCOA7;;chr14:36989427..36989442,-!p1@NKX2-1!1.27!17.61!NKX2-1;;chr5:134369879..134369898,-!p2@PITX1!1.26!17.26!PITX1;;chr6:126240442..126240459,+!p4@NCOA7!1.19!18.32!NCOA7;;chr17:46682321..46682362,-!p1@HOXB6!1.18!14.30!HOXB6;;chr14:36989358..36989378,-!p3@NKX2-1!1.16!13.47!NKX2-1;;chrY:21906594..21906622,-!p1@KDM5D!1.12!12.17!KDM5D;;chr8:67525443..67525459,-!p2@MYBL1!1.07!16.19!MYBL1;;chrY:2803415..2803468,+!p1@ZFY!1.07!10.64!ZFY;;chr15:83953397..83953425,-!p1@BNC1!1.06!12.06!BNC1;;chr3:69811882..69811898,+!p6@MITF!1.05!10.16!MITF;;chr6:126240356..126240379,+!p7@NCOA7!1.04!12.29!NCOA7;;chr3:69811858..69811881,+!p5@MITF!1.03!9.81!MITF;;chr6:10415276..10415341,-!p2@TFAP2A!1.01!11.23!TFAP2A;;chr3:147111198..147111225,+!p4@ZIC1!0.99!8.75!ZIC1;;chr6:126240463..126240489,+!p6@NCOA7!0.97!9.34!NCOA7;;chr19:9609272..9609297,-!p1@ZNF560!0.97!8.39!ZNF560;;chr14:36989336..36989354,-!p5@NKX2-1!0.97!8.39!NKX2-1;;chr7:27153454..27153469,-!p2@HOXA3!0.97!8.27!HOXA3;;chr20:55204351..55204377,+!p1@TFAP2C!0.96!10.40!TFAP2C;;chr17:46690839..46690884,-!p1@HOXB8!0.94!7.80!HOXB8;;chr14:36989940..36989957,-!p2@NKX2-1!0.93!7.45!NKX2-1;;chr12:52445218..52445237,+!p1@NR4A1!0.92!95.74!NR4A1;;chr15:67418119..67418162,+!p5@SMAD3!0.91!8.04!SMAD3;;chr6:10412576..10412599,-!p5@TFAP2A!0.90!6.86!TFAP2A;;chr6:10412477..10412490,-!p10@TFAP2A!0.85!6.15!TFAP2A;;chr14:36989379..36989390,-!p8@NKX2-1!0.85!6.15!NKX2-1;;chr3:141087339..141087387,+!p2@ZBTB38!0.83!63.00!ZBTB38;;chr17:8027418..8027432,-!p1@HES7!0.83!5.79!HES7;;chr7:27135591..27135658,-!p1@HOXA1!0.82!11.35!HOXA1;;chr11:65667884..65667895,-!p2@FOSL1!0.81!22.46!FOSL1;;chr2:46524897..46524911,+!p2@EPAS1!0.81!16.19!EPAS1;;chr1:44513995..44514031,+!p1@KLF17!0.81!5.44!KLF17;;chr17:40477163..40477183,-!p7@STAT3!0.81!5.44!STAT3;;chr20:42295713..42295738,+!p2@MYBL2!0.79!33.45!MYBL2;;chr10:51572408..51572454,+!p3@NCOA4!0.79!32.50!NCOA4;;chr15:67418047..67418093,+!p4@SMAD3!0.79!6.74!SMAD3;;chr5:142780237..142780261,-!p7@NR3C1!0.77!4.85!NR3C1;;chr17:46688334..46688385,-!p1@HOXB7!0.76!7.09!HOXB7;;chr2:191906489..191906517,-!p6@STAT4!0.76!4.73!STAT4;;chr8:67525473..67525518,-!p1@MYBL1!0.75!11.35!MYBL1;;chr5:72744445..72744466,-!p2@FOXD1!0.75!8.04!FOXD1;;chr12:54378923..54378966,+!p1@HOXC10!0.75!4.61!HOXC10;;chr15:67418177..67418204,+!p9@SMAD3!0.74!4.49!SMAD3;;chr17:46703687..46703740,-!p1@HOXB9!0.74!4.49!HOXB9;;chr5:137804484..137804498,+!p2@EGR1!0.73!19.38!EGR1;;chr7:35293685..35293718,-!p1@TBX20!0.73!4.37!TBX20;;chr17:46687959..46688007,-!p2@HOXB7!0.72!6.15!HOXB7;;chr17:36105074..36105086,-!p2@HNF1B!0.72!4.25!HNF1B;;chr9:132427972..132428056,+!p1@PRRX2!0.71!5.56!PRRX2;;chr17:41277372..41277418,-!p1@BRCA1!0.70!16.07!BRCA1;;chr1:247171347..247171366,-!p2@ZNF695!0.70!7.92!ZNF695;;chr18:6414884..6414942,-!p1@L3MBTL4!0.70!5.20!L3MBTL4;;chr5:142780189..142780223,-!p6@NR3C1!0.70!4.02!NR3C1;;chr12:54393880..54393962,+!p1@HOXC9!0.70!4.02!HOXC9;;chr17:46620898..46620927,-!p9@HOXB2!0.69!4.73!HOXB2;;chr1:8935472..8935488,-!p20@ENO1!0.69!3.90!ENO1;;chr20:42295745..42295765,+!p1@MYBL2!0.68!71.15!MYBL2;;chr7:27190547..27190591,-!p1@HOXA6!0.68!3.78!HOXA6;;chr9:100615499..100615519,+!p1@FOXE1!0.68!3.78!FOXE1;;chr1:8938709..8938720,-!p3@ENO1!0.67!204.48!ENO1;;chr10:48355030..48355090,+!p1@ZNF488!0.67!4.96!ZNF488;;chr8:81397876..81397898,+!p5@ZBTB10!0.67!4.49!ZBTB10;;chr17:7197911..7197964,-!p1@YBX2!0.67!3.66!YBX2;;chr14:55493763..55493824,-!p1@WDHD1!0.66!31.44!WDHD1;;chr1:153939955..153940009,+!p2@CREB3L4!0.66!9.10!CREB3L4;;chr6:27356745..27356777,+!p1@ZNF391!0.66!6.26!ZNF391;;chr17:35294075..35294102,+!p1@ENST00000559335!0.66!3.55!LHX1;;chr1:151319710..151319774,-!p1@RFX5!0.65!39.95!RFX5;;chr13:36871902..36872023,-!p1@CCDC169-SOHLH2,p1@CCDC169,p1@SOHLH2!0.65!8.39!SOHLH2;;chr14:37051798..37051831,-!p1@NKX2-8!0.65!3.43!NKX2-8;;chr6:34524093..34524135,-!p1@SPDEF!0.65!3.43!SPDEF;;chr14:62162285..62162296,+!p3@HIF1A!0.64!20.45!HIF1A;;chr20:30193083..30193098,+!p1@ID1!0.63!314.63!ID1;;chr13:73633131..73633149,+!p1@KLF5!0.63!41.13!KLF5;;chr2:75937794..75937867,-!p2@GCFC2!0.63!8.04!GCFC2;;chr6:10415484..10415508,-!p3@TFAP2A!0.63!3.31!TFAP2A;;chr6:34524049..34524089,-!p2@SPDEF!0.63!3.31!SPDEF;;chr9:102584262..102584276,+!p1@NR4A3!0.62!8.04!NR4A3;;chr3:12330560..12330579,+!p1@PPARG!0.62!3.78!PPARG;;chr6:126221034..126221056,+!p13@NCOA7!0.62!3.19!NCOA7;;chr11:19262421..19262455,-!p3@E2F8!0.62!3.19!E2F8;;chr14:36989913..36989931,-!p6@NKX2-1!0.62!3.19!NKX2-1;;chr12:27485762..27485776,+!p3@ARNTL2!0.61!9.34!ARNTL2;;chr14:37051600..37051611,-!p2@NKX2-8!0.61!3.07!NKX2-8;;chr9:11581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| |||
|ffid_belonging_in_development=UBERON:0002532,UBERON:0006595,UBERON:0006603,UBERON:0009847,UBERON:0003353,UBERON:0010316 | |||
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|fonse_cell_line=FF:0101019,FF:0101120 | |fonse_cell_line=FF:0101019,FF:0101120 | ||
|fonse_cell_line_closure=FF:0101019,FF:0101120 | |fonse_cell_line_closure=FF:0101019,FF:0101120 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/prostate%2520cancer%2520cell%2520line%253aDU145.CNhs11260.10490-107B4.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/prostate%2520cancer%2520cell%2520line%253aDU145.CNhs11260.10490-107B4.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/prostate%2520cancer%2520cell%2520line%253aDU145.CNhs11260.10490-107B4.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/prostate%2520cancer%2520cell%2520line%253aDU145.CNhs11260.10490-107B4.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/prostate%2520cancer%2520cell%2520line%253aDU145.CNhs11260.10490-107B4.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10490-107B4 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0101332 | |||
|is_obsolete= | |||
|library_id=CNhs11260 | |||
|library_id_phase_based=2:CNhs11260 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10490 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10490 | |||
|name=prostate cancer cell line:DU145 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11260,LSID758,release008,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.100830886655481,0,0,0,0,0.318146776034739,0,-0.109225621478866,-0.282403560576942,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.104805914553723,0,0,0,0,0,-0.0979578962680575,0,0,-0.132956589778862,0,0,0,0,0,0,0,0,0,0,0.168136510714648,0,-0.0450688303105315,0,0,0,0,0,0,0,0,4.3526784518088e-05,0,0,0,0,0,0,0,-0.00483769174139123,0,0,-0.097343627213097,0,0,0,0,0,0,0,0,0.0921546695012139,0,0,0,0,0,0,0,0,0.0419544352481519,0,0,0,0,0,0,0.041984420254391,0,0,0,-0.05372403630001,0.0824778369254107,0,0,0.0242585478973525,0.0485170957947049,-0.00588068173649252,-0.114218652903543,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0062124723953441,0,0,0,-0.0557738763863767,-0.122471906601633,0,0,0,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0.0921546695012139,-0.00588068173649252,0,0.0485170957947049,0,0.0485170957947049,0,0,0,0,0,0,0,0.0916636119939882,0.0242585478973525,0.318342524214048,0.0581466307874908,0.0242585478973525,0,0.0924330407106728,0,0.404238279270338,0,0,0.0921546695012139,0,0.201661773310963,0.232783494141567,0,-0.128119866952565,0,-0.0504125515893149,0,0,0,0,-0.0186252810838506,0.415098693757587,0,0.00661834244059445,0.0238104084238457,0,0,0,0,-0.140095079226393,0,0.0472570269209075,-0.0827201683234173,-0.0965741626181688,-0.241170633233777,0.0413177450482327,0,0,0,-0.479843826644781,0.529103053386293,0,0,0.225563934367202,0.0944760674831485,0,0,-0.391044581551635,0,-0.331009163375936,0.0464483436578565,0,0.13685328739944,0,0,0,0,0,0.0921546695012139,0,0.0485170957947049,0,0,0,-0.0089763710267318,0.151476209442157,0.0572489713164658,0.314655943152757,0.690231243089795,0,-0.101062866033601,0,0.0574029576955002,0.316945087133228,-0.123083726519821,0.0241210839422508,-0.213503840037921,0,-0.253872631215208,-0.116949172546123,-0.443250109095201,-0.255731430897339,-0.147401849371139,-0.189981719549847,0,-0.0954463458084763,-0.0465922423470382,0.111599008130094,0.145542797277534,-0.071715014658847,-0.414828489836419,0.00760464323647714,0,0.314655943152757,0,-0.0162150055412713,0,0.0485170957947049,-0.358309567217245,-0.0198781092274785,-0.0919812683125181,-0.24551051788323,-0.0732117226904505,0.183871788940442,0.183698016749472,-0.0334187499947136,-0.0234945726944124,-0.229814894217216,0.0485170957947049,0,-0.0095918970613884,-0.0452405190175299,-0.0279277774697545,0.0417856058270709,0,-0.100462600438014,0.0238104084238457,0,-0.185532159336079,0.112752598365258,0,0.0485170957947049,0.282414960139466,0,0,0,0.0429256970873804,0,0.193661962942472,0.0949274402007072,-0.0647190508408966,0,-0.111615527474925,0.0708722901036401,-0.152764800947667,0,-0.164316674165455,0.0285735252693109,-0.205919482860078,-0.173603684386991,0,0.00919881165561245,0.0613224606894546,0.0677927978025643,0.0728010043496076,0.497887581297335,-0.0508439345430601,-0.304142372479988,-0.0513207993106546,-0.364922161888345,0.0389030101604994,-0.0881268324752877,0,-0.286415171168737,-0.679498131621524,0,0.0499829701294479,0,-0.544529352569004,0,0.0557955086152264,0,-0.0875373877008142,0.0159006566359202,-0.439289374580686,-0.011716051469485,0,0.0166025129188214,0.68320345960449,0,0.0937573067741362,0,0.442935400151253,0.0177694273800088,0.041984420254391,-0.043513917149941,0.0927531170531453,0,-0.155660575158783,0,0,0.46481363670439,0.12627676941582,0,-0.00100321427749585,0.081028328876399,0.0419544352481519,-0.0674539776402292,0,0,-0.412916843851158,0,0,0.240896637229276,0,0.459109281018003,-0.161171671985542,-0.072390354141816,-0.108622809454255,0,0,0.317668043776169,0,-0.200182471300137,0.00158286722969816,0.168136510714648,0.013538745361613,0,0,0,0,0,0,-0.0589565109853561,0,0,0,0,0,0.115487823720945,0.215529590025342,0,0.0921546695012139,0,0,0,0,0.289042558809839,-0.0375692482311526,0.0155302912925929,0,0.0084871815120584,-0.0108573559413053,-0.0745003198817154,0.0242585478973525,0,0.0242585478973525,0,0.167791458819492,-0.0351000513800756,0.0485170957947049,0.0362738042170165,0,0.0242585478973525,0.0921546695012139,0,-0.0861409897892114,0,0,0.0460773347506069,0.0901611215271169,-0.00921336125895914,-0.110209647596751,0,0,0,-0.27695440160179,0,0,0,0,-0.135355837899039,0,0.0485170957947049,0.105328930974918,0,-0.0307401487798942,0.120079893764121,0,0.357384442376722,-0.0303650542223788,0.63539924509941,0,0,-0.0596853584789248,0,0,0.148788400592428,0,0.0485170957947049,0,0,0,0,0,0.0921546695012139,0,0.312525571521117,0.0460773347506069,0,0,0,0,0.168136510714648,0,0.168136510714648,0,0.0242585478973525,0,-0.199365852078919,-0.0922240566585104,0.167987819153273,0,0,0,0.00655036918194275,0,0,0.0660550984482138,0.172277793104257,0,0,0,0,0,0.0921546695012139,0,0,-0.0284905395119894,0,0,0,0,0,-0.00483769174139123,0,0,0,0.201661773310963,-0.564807121153884,0,0,-0.109225621478866,0,0,0,0,0,0,0,0,0,0,0,0,0,0.191336857117309,-0.229756768777239,0,0,0,0,0,0,0,-0.106696787491442,0,0,0,0,-0.0653672779142723,0,0,0,0.0968653885218063,0,0.318146776034739,0,0.0485170957947049,0,0,0,0.105702365937376,0.084068255357324,0,0,0,0,0,0,0,0,0,0,0.434100769154664,0,0,0,0.0121016944231325,0,0,0.127777608959178,0,0,-0.0517519490429375,0,0,0,0,0,0,0.0147369107220799,0.0142225191560167,0,0,0,0,0,0,0.0242585478973525,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.017717751250585,0,0,0,0,0,0,0,-0.0979578962680575,0,0,0.189674480445059,0,0,0,0,0.0238254441772446,0,0.280402531584745,0.194796094793631,-0.0715309686568159,0,0,0,0.12260344934501,0,0,0,0,-0.0667773874189013,0,0,0,0,0,0,0,0,0.0485170957947049,0,0,0,0,0,0,0,0,0.0485170957947049,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.104805914553723,0,0,0.0485170957947049,0,0,0,0,0,0,0,0,0,0.263420041960437,0,0,0,0,0,0,0,0,0,0,0,0,0.131805147259529,0,0.338842487279553,0.0460773347506069,0,0,0,0,0,0,-0.0097528153780641,0.0921546695012139,0,0,0,0,0,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| |||
|rna_box=107 | |||
|rna_catalog_number= | |||
|rna_concentration=2.33707 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.02 | |||
|rna_od260/280=2.06 | |||
|rna_position=B4 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=107B4 | |||
|rna_weight_ug=58.42675 | |||
|sample_age=69 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB2143 | |||
|sample_cell_line=DU145 | |||
|sample_cell_lot= | |||
|sample_cell_type=unclassifiable | |||
|sample_collaboration=Yukio Nakamura (RIKEN BRC) | |||
|sample_company=RIKEN Bioresource centre | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=prostate cancer | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=C | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;6.421557954328e-280!GO:0043226;organelle;7.03944896880694e-228!GO:0043229;intracellular organelle;2.59031892474953e-227!GO:0043227;membrane-bound organelle;2.42697939929845e-219!GO:0043231;intracellular membrane-bound organelle;2.42697939929845e-219!GO:0005737;cytoplasm;5.58419066756614e-207!GO:0044422;organelle part;1.65396883847426e-168!GO:0044446;intracellular organelle part;8.03790206093028e-167!GO:0044444;cytoplasmic part;8.30571869360604e-144!GO:0032991;macromolecular complex;1.65162058510916e-111!GO:0044237;cellular metabolic process;2.08374760524627e-98!GO:0044238;primary metabolic process;2.78364643791251e-96!GO:0030529;ribonucleoprotein complex;5.06048433144569e-96!GO:0005634;nucleus;7.35159429953044e-93!GO:0043170;macromolecule metabolic process;1.54253537243382e-88!GO:0044428;nuclear part;1.90048976139395e-86!GO:0043233;organelle lumen;7.55048269251076e-83!GO:0031974;membrane-enclosed lumen;7.55048269251076e-83!GO:0005739;mitochondrion;1.26851422644206e-82!GO:0003723;RNA binding;1.14880893358499e-79!GO:0005515;protein binding;2.29958156522087e-68!GO:0005840;ribosome;1.13277864830566e-57!GO:0006396;RNA processing;4.19557341055595e-56!GO:0043234;protein complex;5.33966526196532e-56!GO:0006412;translation;9.58054224145245e-55!GO:0031090;organelle membrane;1.19690510644656e-54!GO:0044429;mitochondrial part;2.48135609913386e-53!GO:0043283;biopolymer metabolic process;6.4717713229356e-53!GO:0016043;cellular component organization and biogenesis;1.74932405348156e-52!GO:0003735;structural constituent of ribosome;1.1290654908333e-49!GO:0031967;organelle envelope;1.94067849424778e-49!GO:0031975;envelope;5.64192079270579e-49!GO:0031981;nuclear lumen;5.98047674850907e-49!GO:0019538;protein metabolic process;8.70448455273435e-49!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.99304368766471e-46!GO:0043228;non-membrane-bound organelle;1.87719223169736e-45!GO:0043232;intracellular non-membrane-bound organelle;1.87719223169736e-45!GO:0009058;biosynthetic process;1.33528184990992e-44!GO:0033036;macromolecule localization;1.76427913914176e-44!GO:0015031;protein transport;5.18063921344112e-44!GO:0044260;cellular macromolecule metabolic process;1.85932836554072e-43!GO:0010467;gene expression;2.02230141507558e-43!GO:0044267;cellular protein metabolic process;2.25850180128849e-43!GO:0044249;cellular biosynthetic process;3.21705692296519e-43!GO:0033279;ribosomal subunit;1.94172220626987e-42!GO:0005829;cytosol;2.74791151082815e-42!GO:0016071;mRNA metabolic process;3.47613546634978e-42!GO:0009059;macromolecule biosynthetic process;1.12619695254821e-41!GO:0008104;protein localization;1.08367461933652e-40!GO:0045184;establishment of protein localization;6.92858038561262e-40!GO:0006259;DNA metabolic process;1.18844726834837e-39!GO:0008380;RNA splicing;1.98538567434128e-39!GO:0006996;organelle organization and biogenesis;7.91295963222432e-39!GO:0007049;cell cycle;3.28703657767851e-37!GO:0006397;mRNA processing;4.88729363014839e-37!GO:0046907;intracellular transport;6.39654389340389e-37!GO:0065003;macromolecular complex assembly;1.33149859273812e-34!GO:0005740;mitochondrial envelope;4.17233595536203e-33!GO:0022613;ribonucleoprotein complex biogenesis and assembly;6.20563675579936e-32!GO:0000166;nucleotide binding;1.9551384317298e-31!GO:0019866;organelle inner membrane;2.06998598579519e-31!GO:0022607;cellular component assembly;6.24971686848948e-31!GO:0031966;mitochondrial membrane;9.03486313614736e-31!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.12749897174765e-30!GO:0006886;intracellular protein transport;2.21832063064769e-29!GO:0005743;mitochondrial inner membrane;7.13502797522864e-29!GO:0005681;spliceosome;1.09794557680707e-28!GO:0005654;nucleoplasm;1.35030115517514e-28!GO:0016462;pyrophosphatase activity;7.8965446325694e-28!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;9.64780672782975e-28!GO:0000278;mitotic cell cycle;1.09420318214778e-27!GO:0022402;cell cycle process;1.46334557788245e-27!GO:0016817;hydrolase activity, acting on acid anhydrides;1.7071457092795e-27!GO:0017111;nucleoside-triphosphatase activity;1.4895115053969e-26!GO:0003676;nucleic acid binding;4.06851116046501e-26!GO:0051649;establishment of cellular localization;5.10288772812547e-25!GO:0051641;cellular localization;9.705833027877e-25!GO:0012505;endomembrane system;2.71233334410096e-24!GO:0006974;response to DNA damage stimulus;4.68984695823539e-24!GO:0031980;mitochondrial lumen;6.68245563396388e-24!GO:0005759;mitochondrial matrix;6.68245563396388e-24!GO:0044445;cytosolic part;1.55042943270211e-23!GO:0006119;oxidative phosphorylation;3.80879150418644e-23!GO:0044451;nucleoplasm part;4.39615008854041e-23!GO:0032553;ribonucleotide binding;7.86419079105141e-23!GO:0032555;purine ribonucleotide binding;7.86419079105141e-23!GO:0017076;purine nucleotide binding;8.99714730404537e-23!GO:0016874;ligase activity;9.34235810011504e-23!GO:0022403;cell cycle phase;1.6848993810091e-22!GO:0015935;small ribosomal subunit;3.19837711783641e-22!GO:0000087;M phase of mitotic cell cycle;4.56392600615033e-22!GO:0044455;mitochondrial membrane part;8.17445285999037e-22!GO:0007067;mitosis;1.32628055367287e-21!GO:0015934;large ribosomal subunit;2.45236090889041e-21!GO:0005730;nucleolus;5.70171159470649e-21!GO:0006281;DNA repair;6.07388377114935e-21!GO:0006512;ubiquitin cycle;7.41105021784694e-21!GO:0005694;chromosome;7.98874208000266e-21!GO:0051301;cell division;3.82484269918661e-20!GO:0051186;cofactor metabolic process;5.69991596686046e-20!GO:0006457;protein folding;1.37845596803087e-19!GO:0016070;RNA metabolic process;2.54717547005839e-19!GO:0005524;ATP binding;4.29475440147647e-19!GO:0000279;M phase;4.29475440147647e-19!GO:0006260;DNA replication;5.79346733691932e-19!GO:0032559;adenyl ribonucleotide binding;8.35344219886325e-19!GO:0044265;cellular macromolecule catabolic process;1.13310622229157e-18!GO:0022618;protein-RNA complex assembly;1.22534573794212e-18!GO:0030554;adenyl nucleotide binding;1.43389839063192e-18!GO:0051603;proteolysis involved in cellular protein catabolic process;3.12341753303492e-18!GO:0019941;modification-dependent protein catabolic process;4.72310594802015e-18!GO:0043632;modification-dependent macromolecule catabolic process;4.72310594802015e-18!GO:0044427;chromosomal part;5.13953805315083e-18!GO:0044257;cellular protein catabolic process;7.92211416112406e-18!GO:0006511;ubiquitin-dependent protein catabolic process;8.47791845234399e-18!GO:0044248;cellular catabolic process;1.30219293075585e-17!GO:0000502;proteasome complex (sensu Eukaryota);2.47841833236439e-17!GO:0005746;mitochondrial respiratory chain;2.80232694984583e-17!GO:0005635;nuclear envelope;3.22992919606822e-17!GO:0005783;endoplasmic reticulum;3.22992919606822e-17!GO:0009719;response to endogenous stimulus;4.50522802755605e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;5.27872654014194e-17!GO:0008135;translation factor activity, nucleic acid binding;6.01094805536073e-17!GO:0005761;mitochondrial ribosome;2.18439909875476e-16!GO:0000313;organellar ribosome;2.18439909875476e-16!GO:0006732;coenzyme metabolic process;2.37153283752749e-16!GO:0044432;endoplasmic reticulum part;3.02597143364336e-16!GO:0043285;biopolymer catabolic process;3.04712504502913e-16!GO:0048770;pigment granule;3.47716921917968e-16!GO:0042470;melanosome;3.47716921917968e-16!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);5.98122307852846e-16!GO:0051276;chromosome organization and biogenesis;1.0836979128613e-15!GO:0016887;ATPase activity;1.57654457887363e-15!GO:0009057;macromolecule catabolic process;1.71013326815927e-15!GO:0042623;ATPase activity, coupled;1.71568127677764e-15!GO:0050136;NADH dehydrogenase (quinone) activity;2.07724301088792e-15!GO:0003954;NADH dehydrogenase activity;2.07724301088792e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.07724301088792e-15!GO:0031965;nuclear membrane;4.22579456698541e-15!GO:0044453;nuclear membrane part;4.95692975350702e-15!GO:0043412;biopolymer modification;6.23472466145287e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;6.38743084573575e-15!GO:0000375;RNA splicing, via transesterification reactions;6.38743084573575e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;6.38743084573575e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);7.39255003298344e-15!GO:0030163;protein catabolic process;9.21608224819756e-15!GO:0042254;ribosome biogenesis and assembly;1.5468533332379e-14!GO:0006605;protein targeting;1.5468533332379e-14!GO:0051082;unfolded protein binding;2.0836941352163e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.98312759502352e-14!GO:0008134;transcription factor binding;3.6084641448617e-14!GO:0042775;organelle ATP synthesis coupled electron transport;4.71372644795927e-14!GO:0042773;ATP synthesis coupled electron transport;4.71372644795927e-14!GO:0006399;tRNA metabolic process;7.89970547145607e-14!GO:0048193;Golgi vesicle transport;1.57867010892643e-13!GO:0030964;NADH dehydrogenase complex (quinone);1.96469627899471e-13!GO:0045271;respiratory chain complex I;1.96469627899471e-13!GO:0005747;mitochondrial respiratory chain complex I;1.96469627899471e-13!GO:0051726;regulation of cell cycle;2.63080247795169e-13!GO:0000074;regulation of progression through cell cycle;3.36215644762073e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;4.75468272108869e-13!GO:0016192;vesicle-mediated transport;5.29770167922598e-13!GO:0005643;nuclear pore;9.2683985126593e-13!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.03959181070953e-12!GO:0006464;protein modification process;1.30116920671973e-12!GO:0005789;endoplasmic reticulum membrane;2.15890622821722e-12!GO:0012501;programmed cell death;2.70891966062854e-12!GO:0005794;Golgi apparatus;2.79883770294132e-12!GO:0006915;apoptosis;3.1929497862895e-12!GO:0008639;small protein conjugating enzyme activity;4.09417538138037e-12!GO:0016879;ligase activity, forming carbon-nitrogen bonds;4.29612678822696e-12!GO:0004386;helicase activity;4.50817080616812e-12!GO:0003743;translation initiation factor activity;5.35870541867382e-12!GO:0016604;nuclear body;5.44110484997128e-12!GO:0004842;ubiquitin-protein ligase activity;6.55791659211594e-12!GO:0006913;nucleocytoplasmic transport;6.95980213576877e-12!GO:0009055;electron carrier activity;9.37788624840984e-12!GO:0006413;translational initiation;1.40223981574493e-11!GO:0019787;small conjugating protein ligase activity;1.74366888291662e-11!GO:0051169;nuclear transport;1.92060515375122e-11!GO:0043687;post-translational protein modification;2.10318650581454e-11!GO:0006325;establishment and/or maintenance of chromatin architecture;2.14264991796939e-11!GO:0051188;cofactor biosynthetic process;2.8376006720267e-11!GO:0065002;intracellular protein transport across a membrane;3.53237700327793e-11!GO:0050657;nucleic acid transport;3.77890044459361e-11!GO:0051236;establishment of RNA localization;3.77890044459361e-11!GO:0050658;RNA transport;3.77890044459361e-11!GO:0008026;ATP-dependent helicase activity;3.96798127012543e-11!GO:0006403;RNA localization;4.20691451407084e-11!GO:0006461;protein complex assembly;4.63827462462193e-11!GO:0008219;cell death;5.24273177428282e-11!GO:0016265;death;5.24273177428282e-11!GO:0006323;DNA packaging;7.11188420834292e-11!GO:0009259;ribonucleotide metabolic process;1.28207143680101e-10!GO:0006163;purine nucleotide metabolic process;1.41107459167181e-10!GO:0006446;regulation of translational initiation;1.70222147312644e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.34029757000095e-10!GO:0016881;acid-amino acid ligase activity;2.88467761173781e-10!GO:0009060;aerobic respiration;3.79092854797103e-10!GO:0015630;microtubule cytoskeleton;4.12046828665862e-10!GO:0046930;pore complex;4.63788012774385e-10!GO:0009056;catabolic process;5.06079376467683e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;5.72629557799271e-10!GO:0004812;aminoacyl-tRNA ligase activity;5.72629557799271e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;5.72629557799271e-10!GO:0043038;amino acid activation;6.46499277010185e-10!GO:0006418;tRNA aminoacylation for protein translation;6.46499277010185e-10!GO:0043039;tRNA aminoacylation;6.46499277010185e-10!GO:0006364;rRNA processing;9.081028391091e-10!GO:0008565;protein transporter activity;1.02209214609694e-09!GO:0006366;transcription from RNA polymerase II promoter;1.06280703642553e-09!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.32473335407354e-09!GO:0006164;purine nucleotide biosynthetic process;1.44537068745599e-09!GO:0009150;purine ribonucleotide metabolic process;1.55844540095364e-09!GO:0000775;chromosome, pericentric region;1.63013137050785e-09!GO:0016740;transferase activity;1.81761196817487e-09!GO:0045333;cellular respiration;2.12472098264517e-09!GO:0016072;rRNA metabolic process;2.22780635063434e-09!GO:0009108;coenzyme biosynthetic process;2.22780635063434e-09!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.44392312362817e-09!GO:0051028;mRNA transport;2.5165964400513e-09!GO:0006261;DNA-dependent DNA replication;3.01147781778875e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;4.15551470790211e-09!GO:0009260;ribonucleotide biosynthetic process;4.80456504802355e-09!GO:0030532;small nuclear ribonucleoprotein complex;6.42220238667362e-09!GO:0007005;mitochondrion organization and biogenesis;6.82022962027719e-09!GO:0016607;nuclear speck;7.16327387554318e-09!GO:0003924;GTPase activity;7.16358809751721e-09!GO:0009141;nucleoside triphosphate metabolic process;8.79808230250931e-09!GO:0009199;ribonucleoside triphosphate metabolic process;1.11271667996139e-08!GO:0017038;protein import;1.24709158095934e-08!GO:0009152;purine ribonucleotide biosynthetic process;1.60453463942849e-08!GO:0015986;ATP synthesis coupled proton transport;1.77495033759273e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.77495033759273e-08!GO:0065004;protein-DNA complex assembly;1.81547314545195e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.89357337369088e-08!GO:0009144;purine nucleoside triphosphate metabolic process;1.89357337369088e-08!GO:0016779;nucleotidyltransferase activity;1.93864397662502e-08!GO:0009117;nucleotide metabolic process;2.85115284899344e-08!GO:0006099;tricarboxylic acid cycle;3.36308647660599e-08!GO:0046356;acetyl-CoA catabolic process;3.36308647660599e-08!GO:0009142;nucleoside triphosphate biosynthetic process;3.65201425838169e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;3.65201425838169e-08!GO:0003712;transcription cofactor activity;3.83708688870467e-08!GO:0005819;spindle;4.05350421327359e-08!GO:0007051;spindle organization and biogenesis;4.06849943417849e-08!GO:0016787;hydrolase activity;4.36039363062738e-08!GO:0019829;cation-transporting ATPase activity;4.53317670272417e-08!GO:0000785;chromatin;4.54838117535333e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;4.57542416669724e-08!GO:0042981;regulation of apoptosis;4.57542416669724e-08!GO:0016568;chromatin modification;4.80379392411744e-08!GO:0043623;cellular protein complex assembly;4.8986317427609e-08!GO:0043067;regulation of programmed cell death;5.70929067298944e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;6.24898935333113e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;6.24898935333113e-08!GO:0015078;hydrogen ion transmembrane transporter activity;6.33899666164274e-08!GO:0032446;protein modification by small protein conjugation;7.21990312642367e-08!GO:0005768;endosome;7.98945884134291e-08!GO:0046034;ATP metabolic process;1.04151423397623e-07!GO:0006333;chromatin assembly or disassembly;1.09244181974752e-07!GO:0016567;protein ubiquitination;1.15020392241519e-07!GO:0051329;interphase of mitotic cell cycle;1.26675003556125e-07!GO:0051325;interphase;1.34725568397245e-07!GO:0006084;acetyl-CoA metabolic process;1.36709606168472e-07!GO:0000075;cell cycle checkpoint;2.00644209510925e-07!GO:0043566;structure-specific DNA binding;2.19967570462735e-07!GO:0045259;proton-transporting ATP synthase complex;2.2941672569581e-07!GO:0006754;ATP biosynthetic process;2.87368261700652e-07!GO:0006753;nucleoside phosphate metabolic process;2.87368261700652e-07!GO:0016469;proton-transporting two-sector ATPase complex;3.96985273316594e-07!GO:0009109;coenzyme catabolic process;4.27472953112555e-07!GO:0051187;cofactor catabolic process;4.27607924770406e-07!GO:0005839;proteasome core complex (sensu Eukaryota);4.31870418914645e-07!GO:0051246;regulation of protein metabolic process;4.84748253582781e-07!GO:0003697;single-stranded DNA binding;5.55305287958148e-07!GO:0000245;spliceosome assembly;5.98887093288842e-07!GO:0005813;centrosome;8.05207487200496e-07!GO:0005793;ER-Golgi intermediate compartment;9.10807964106555e-07!GO:0016491;oxidoreductase activity;9.23580338663631e-07!GO:0005525;GTP binding;9.55302537869102e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.16849425772942e-06!GO:0005815;microtubule organizing center;1.41879706613798e-06!GO:0005657;replication fork;1.42021367864123e-06!GO:0051170;nuclear import;1.86314881049424e-06!GO:0050794;regulation of cellular process;1.9111218382747e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;2.25710863083315e-06!GO:0005667;transcription factor complex;2.3551785611852e-06!GO:0048475;coated membrane;2.5363625085353e-06!GO:0030117;membrane coat;2.5363625085353e-06!GO:0043069;negative regulation of programmed cell death;2.58961003334363e-06!GO:0003724;RNA helicase activity;2.72550853500496e-06!GO:0006752;group transfer coenzyme metabolic process;2.99698462432241e-06!GO:0006613;cotranslational protein targeting to membrane;2.99698462432241e-06!GO:0006793;phosphorus metabolic process;3.13842300638271e-06!GO:0006796;phosphate metabolic process;3.13842300638271e-06!GO:0004298;threonine endopeptidase activity;3.20256871068299e-06!GO:0000151;ubiquitin ligase complex;3.27882284589846e-06!GO:0030120;vesicle coat;3.39090823504755e-06!GO:0030662;coated vesicle membrane;3.39090823504755e-06!GO:0006888;ER to Golgi vesicle-mediated transport;3.49797298989438e-06!GO:0006916;anti-apoptosis;3.79776049785333e-06!GO:0043066;negative regulation of apoptosis;4.08652349028575e-06!GO:0007010;cytoskeleton organization and biogenesis;4.50523866949716e-06!GO:0007088;regulation of mitosis;5.08602056812378e-06!GO:0008654;phospholipid biosynthetic process;5.78548851182709e-06!GO:0008094;DNA-dependent ATPase activity;6.17964902405022e-06!GO:0000776;kinetochore;6.43584165055586e-06!GO:0006606;protein import into nucleus;7.18278963043523e-06!GO:0003899;DNA-directed RNA polymerase activity;8.08206335803951e-06!GO:0044431;Golgi apparatus part;9.14097290200367e-06!GO:0031988;membrane-bound vesicle;1.04324035890069e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.04324035890069e-05!GO:0051427;hormone receptor binding;1.12514506991824e-05!GO:0016853;isomerase activity;1.27036764428895e-05!GO:0016023;cytoplasmic membrane-bound vesicle;1.47471616122715e-05!GO:0005762;mitochondrial large ribosomal subunit;1.6029688044481e-05!GO:0000315;organellar large ribosomal subunit;1.6029688044481e-05!GO:0006334;nucleosome assembly;1.68610211047357e-05!GO:0019843;rRNA binding;1.89931372800914e-05!GO:0008033;tRNA processing;2.02062012405331e-05!GO:0016310;phosphorylation;2.13760994501447e-05!GO:0015980;energy derivation by oxidation of organic compounds;2.25625799434434e-05!GO:0045454;cell redox homeostasis;2.35781938876595e-05!GO:0032561;guanyl ribonucleotide binding;2.42821691509492e-05!GO:0019001;guanyl nucleotide binding;2.42821691509492e-05!GO:0044440;endosomal part;2.45668667778042e-05!GO:0010008;endosome membrane;2.45668667778042e-05!GO:0005773;vacuole;2.45849151749032e-05!GO:0035257;nuclear hormone receptor binding;2.55171784789098e-05!GO:0005788;endoplasmic reticulum lumen;3.15773488728911e-05!GO:0000314;organellar small ribosomal subunit;3.43258006329657e-05!GO:0005763;mitochondrial small ribosomal subunit;3.43258006329657e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;3.45587678254068e-05!GO:0048523;negative regulation of cellular process;3.59021641284112e-05!GO:0031497;chromatin assembly;4.04136509812621e-05!GO:0000079;regulation of cyclin-dependent protein kinase activity;4.18457384873825e-05!GO:0005770;late endosome;4.26462749824444e-05!GO:0031982;vesicle;4.84923056929922e-05!GO:0045786;negative regulation of progression through cell cycle;5.00651638114199e-05!GO:0000323;lytic vacuole;5.02218495633254e-05!GO:0005764;lysosome;5.02218495633254e-05!GO:0019899;enzyme binding;5.48344751600913e-05!GO:0043021;ribonucleoprotein binding;5.62926808983429e-05!GO:0051052;regulation of DNA metabolic process;6.10240286614646e-05!GO:0051168;nuclear export;6.42135916384304e-05!GO:0008186;RNA-dependent ATPase activity;6.90938678458211e-05!GO:0007059;chromosome segregation;7.28965958366674e-05!GO:0016563;transcription activator activity;7.53306766702162e-05!GO:0006302;double-strand break repair;7.65636747445944e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;7.76218064308639e-05!GO:0031410;cytoplasmic vesicle;7.81905191017389e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;8.5661614274059e-05!GO:0050662;coenzyme binding;9.11917719471504e-05!GO:0006091;generation of precursor metabolites and energy;9.20356192584128e-05!GO:0000139;Golgi membrane;9.7110471973178e-05!GO:0048471;perinuclear region of cytoplasm;9.97995218105574e-05!GO:0003713;transcription coactivator activity;0.000103821996019877!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.000105845504616757!GO:0046489;phosphoinositide biosynthetic process;0.000106347128809227!GO:0005874;microtubule;0.000107155621197792!GO:0006414;translational elongation;0.000107834789476229!GO:0046474;glycerophospholipid biosynthetic process;0.000118197249667164!GO:0030867;rough endoplasmic reticulum membrane;0.000126218629075207!GO:0005048;signal sequence binding;0.000130937550383462!GO:0031324;negative regulation of cellular metabolic process;0.000139088186717045!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.000150287005192022!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.000150553821039208!GO:0016363;nuclear matrix;0.000150579977410667!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000159035692698133!GO:0015399;primary active transmembrane transporter activity;0.000159035692698133!GO:0007093;mitotic cell cycle checkpoint;0.000163373444148756!GO:0016741;transferase activity, transferring one-carbon groups;0.000186078882211412!GO:0019752;carboxylic acid metabolic process;0.000201107500060671!GO:0004004;ATP-dependent RNA helicase activity;0.000213684884573206!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000215224194643136!GO:0008168;methyltransferase activity;0.000236331423645043!GO:0006612;protein targeting to membrane;0.000236331423645043!GO:0007017;microtubule-based process;0.000236331423645043!GO:0006082;organic acid metabolic process;0.00023683183015871!GO:0007052;mitotic spindle organization and biogenesis;0.00027141056075306!GO:0009892;negative regulation of metabolic process;0.000273721665082438!GO:0005798;Golgi-associated vesicle;0.000280318593351697!GO:0030036;actin cytoskeleton organization and biogenesis;0.000302379915625274!GO:0043681;protein import into mitochondrion;0.000302448931702324!GO:0008250;oligosaccharyl transferase complex;0.000305553574125015!GO:0006383;transcription from RNA polymerase III promoter;0.000325863644052485!GO:0042802;identical protein binding;0.000361547799781528!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.000364216406163891!GO:0003690;double-stranded DNA binding;0.000375887867878438!GO:0048519;negative regulation of biological process;0.000377425063539689!GO:0006275;regulation of DNA replication;0.000378651847838184!GO:0046467;membrane lipid biosynthetic process;0.00038056722830913!GO:0016126;sterol biosynthetic process;0.000409701562568718!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00041196565666541!GO:0006839;mitochondrial transport;0.000417825039661972!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.000424932149559315!GO:0018196;peptidyl-asparagine modification;0.000432379605352981!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.000432379605352981!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000434141736084536!GO:0006626;protein targeting to mitochondrion;0.000448869608946523!GO:0016859;cis-trans isomerase activity;0.000458525594489032!GO:0003746;translation elongation factor activity;0.000478873606267116!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000481863468048587!GO:0004576;oligosaccharyl transferase activity;0.00048256934580448!GO:0003684;damaged DNA binding;0.00050748131129403!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000543730376798035!GO:0009165;nucleotide biosynthetic process;0.000543730376798035!GO:0031252;leading edge;0.000545444078947242!GO:0005769;early endosome;0.000574718991348519!GO:0003678;DNA helicase activity;0.000582572169239975!GO:0016044;membrane organization and biogenesis;0.0005839173712292!GO:0000082;G1/S transition of mitotic cell cycle;0.000593862348660797!GO:0009116;nucleoside metabolic process;0.000604636380735196!GO:0000059;protein import into nucleus, docking;0.000673225728577627!GO:0006310;DNA recombination;0.00068161792476578!GO:0005885;Arp2/3 protein complex;0.000681909008394976!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.000698146002899276!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.000698146002899276!GO:0016564;transcription repressor activity;0.000709904567145917!GO:0046483;heterocycle metabolic process;0.000720870710992572!GO:0005684;U2-dependent spliceosome;0.000785619653639016!GO:0003729;mRNA binding;0.000788933967913363!GO:0015992;proton transport;0.000788933967913363!GO:0031968;organelle outer membrane;0.000812056628169578!GO:0044452;nucleolar part;0.000820652118832503!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000829277218233914!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000829277218233914!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000829277218233914!GO:0048500;signal recognition particle;0.000830483272998746!GO:0051252;regulation of RNA metabolic process;0.000836080860374105!GO:0006352;transcription initiation;0.000836080860374105!GO:0051920;peroxiredoxin activity;0.000836582956695209!GO:0019867;outer membrane;0.000836582956695209!GO:0019222;regulation of metabolic process;0.000836582956695209!GO:0006520;amino acid metabolic process;0.000864747999892621!GO:0031970;organelle envelope lumen;0.000899745229497442!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000911951185865082!GO:0006818;hydrogen transport;0.000933914735647277!GO:0007264;small GTPase mediated signal transduction;0.00101286248445859!GO:0003714;transcription corepressor activity;0.00101508666580363!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0010750768489585!GO:0006695;cholesterol biosynthetic process;0.00109476005388347!GO:0008361;regulation of cell size;0.00114697711892432!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00116247703755193!GO:0051087;chaperone binding;0.00120040996928791!GO:0048037;cofactor binding;0.00126075030997741!GO:0033116;ER-Golgi intermediate compartment membrane;0.00126324456539072!GO:0000049;tRNA binding;0.00129181585981946!GO:0008312;7S RNA binding;0.00129181585981946!GO:0005637;nuclear inner membrane;0.00130264428864695!GO:0005905;coated pit;0.00130266712345579!GO:0004674;protein serine/threonine kinase activity;0.00133979449053222!GO:0006402;mRNA catabolic process;0.00135316782377321!GO:0008610;lipid biosynthetic process;0.00135427428830033!GO:0043492;ATPase activity, coupled to movement of substances;0.00138210006053339!GO:0051789;response to protein stimulus;0.00138416699528098!GO:0006986;response to unfolded protein;0.00138416699528098!GO:0051287;NAD binding;0.00143418730691175!GO:0000096;sulfur amino acid metabolic process;0.00143427235592999!GO:0050789;regulation of biological process;0.00143525291943056!GO:0031072;heat shock protein binding;0.00144865496995903!GO:0003682;chromatin binding;0.00156773571192664!GO:0003711;transcription elongation regulator activity;0.00156773571192664!GO:0032508;DNA duplex unwinding;0.00158199800909089!GO:0032392;DNA geometric change;0.00158199800909089!GO:0030176;integral to endoplasmic reticulum membrane;0.00163587863768601!GO:0006506;GPI anchor biosynthetic process;0.0016627489358171!GO:0005791;rough endoplasmic reticulum;0.00171367806083697!GO:0007006;mitochondrial membrane organization and biogenesis;0.00172134459979063!GO:0005741;mitochondrial outer membrane;0.00172134459979063!GO:0016251;general RNA polymerase II transcription factor activity;0.00174446114569018!GO:0006891;intra-Golgi vesicle-mediated transport;0.00180830718748538!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00202423252220622!GO:0045047;protein targeting to ER;0.00202423252220622!GO:0004527;exonuclease activity;0.00203487467351245!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00205392952281343!GO:0007243;protein kinase cascade;0.00207337990243309!GO:0001558;regulation of cell growth;0.00207337990243309!GO:0006672;ceramide metabolic process;0.00219942010129407!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00223231282140583!GO:0000910;cytokinesis;0.00224033527441697!GO:0065009;regulation of a molecular function;0.00224986718803313!GO:0006497;protein amino acid lipidation;0.00247799274587331!GO:0016272;prefoldin complex;0.00248101826198797!GO:0043065;positive regulation of apoptosis;0.00251180423052705!GO:0009119;ribonucleoside metabolic process;0.00252539511668042!GO:0006401;RNA catabolic process;0.00260198521289249!GO:0005876;spindle microtubule;0.00260972980838905!GO:0016049;cell growth;0.00260972980838905!GO:0043284;biopolymer biosynthetic process;0.00266586668244161!GO:0030029;actin filament-based process;0.0026966373873859!GO:0008092;cytoskeletal protein binding;0.0026966373873859!GO:0006505;GPI anchor metabolic process;0.00285844471894669!GO:0045045;secretory pathway;0.00286073568636993!GO:0043488;regulation of mRNA stability;0.00287523885475435!GO:0043487;regulation of RNA stability;0.00287523885475435!GO:0030384;phosphoinositide metabolic process;0.00290474254333728!GO:0016197;endosome transport;0.00291434301642907!GO:0006268;DNA unwinding during replication;0.00291732863681929!GO:0051540;metal cluster binding;0.00291732863681929!GO:0051536;iron-sulfur cluster binding;0.00291732863681929!GO:0030663;COPI coated vesicle membrane;0.00292097551491464!GO:0030126;COPI vesicle coat;0.00292097551491464!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00292097551491464!GO:0008139;nuclear localization sequence binding;0.00300028324438125!GO:0042393;histone binding;0.00304581922668232!GO:0006284;base-excision repair;0.00314924709117679!GO:0009112;nucleobase metabolic process;0.00317828971431128!GO:0044262;cellular carbohydrate metabolic process;0.00320027495273336!GO:0000922;spindle pole;0.00328806436080137!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00334926471057081!GO:0015631;tubulin binding;0.00345694006757196!GO:0046519;sphingoid metabolic process;0.00348397040493797!GO:0043068;positive regulation of programmed cell death;0.00357818718425576!GO:0006289;nucleotide-excision repair;0.00366371700111583!GO:0005758;mitochondrial intermembrane space;0.00372924241304717!GO:0006650;glycerophospholipid metabolic process;0.00385975488183758!GO:0000086;G2/M transition of mitotic cell cycle;0.00385975488183758!GO:0006405;RNA export from nucleus;0.00389820965403646!GO:0051101;regulation of DNA binding;0.00422266642440978!GO:0043596;nuclear replication fork;0.00428945561255017!GO:0007050;cell cycle arrest;0.00445882963152953!GO:0022890;inorganic cation transmembrane transporter activity;0.00451647631014515!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0045203194336251!GO:0006144;purine base metabolic process;0.00496483843936643!GO:0030880;RNA polymerase complex;0.00512874925537147!GO:0008234;cysteine-type peptidase activity;0.00516151303791303!GO:0006733;oxidoreduction coenzyme metabolic process;0.00524604908960084!GO:0032259;methylation;0.00526920613949225!GO:0042158;lipoprotein biosynthetic process;0.00527266985771061!GO:0031124;mRNA 3'-end processing;0.00530460608780282!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00539628766321301!GO:0015002;heme-copper terminal oxidase activity;0.00539628766321301!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00539628766321301!GO:0004129;cytochrome-c oxidase activity;0.00539628766321301!GO:0030132;clathrin coat of coated pit;0.00539628766321301!GO:0030137;COPI-coated vesicle;0.0056752214640163!GO:0017166;vinculin binding;0.00581795877497285!GO:0004518;nuclease activity;0.00585572879227934!GO:0031902;late endosome membrane;0.00589784482740582!GO:0008022;protein C-terminus binding;0.00609366232858557!GO:0043022;ribosome binding;0.00617316904939336!GO:0032984;macromolecular complex disassembly;0.00643706421505065!GO:0030118;clathrin coat;0.00661302736305473!GO:0006950;response to stress;0.00661302736305473!GO:0031570;DNA integrity checkpoint;0.00664150241347477!GO:0006509;membrane protein ectodomain proteolysis;0.00669087825860825!GO:0033619;membrane protein proteolysis;0.00669087825860825!GO:0035258;steroid hormone receptor binding;0.00683646680775354!GO:0000287;magnesium ion binding;0.00702081755533516!GO:0042770;DNA damage response, signal transduction;0.00704846413077977!GO:0006338;chromatin remodeling;0.00710419169735868!GO:0043624;cellular protein complex disassembly;0.00728322499468279!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.00730897089143156!GO:0000228;nuclear chromosome;0.00732839250334229!GO:0051098;regulation of binding;0.00733163359597755!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00739112401388798!GO:0048487;beta-tubulin binding;0.00756532349299274!GO:0009451;RNA modification;0.00778757874611244!GO:0000786;nucleosome;0.00790075835943129!GO:0030133;transport vesicle;0.00814557806354624!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.00819548348800949!GO:0006611;protein export from nucleus;0.00826859002295554!GO:0030521;androgen receptor signaling pathway;0.00833701031946775!GO:0046128;purine ribonucleoside metabolic process;0.0085566612140988!GO:0042278;purine nucleoside metabolic process;0.0085566612140988!GO:0000070;mitotic sister chromatid segregation;0.00863799074435532!GO:0005832;chaperonin-containing T-complex;0.00874027007627405!GO:0043241;protein complex disassembly;0.00874027007627405!GO:0016481;negative regulation of transcription;0.00882352327972248!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0089793981939215!GO:0019783;small conjugating protein-specific protease activity;0.009184816604497!GO:0016407;acetyltransferase activity;0.00933050685894903!GO:0006767;water-soluble vitamin metabolic process;0.00933050685894903!GO:0000819;sister chromatid segregation;0.00944870302908408!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00955225262294249!GO:0000428;DNA-directed RNA polymerase complex;0.00955225262294249!GO:0008632;apoptotic program;0.00959157465223085!GO:0006749;glutathione metabolic process;0.00968988169651836!GO:0000339;RNA cap binding;0.0102929869585417!GO:0006519;amino acid and derivative metabolic process;0.0103054200233025!GO:0006892;post-Golgi vesicle-mediated transport;0.0104015013826903!GO:0008652;amino acid biosynthetic process;0.0106211086050074!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0107976749654043!GO:0005869;dynactin complex;0.010801318129141!GO:0022406;membrane docking;0.010812646845024!GO:0048278;vesicle docking;0.010812646845024!GO:0006595;polyamine metabolic process;0.0111550724423969!GO:0004843;ubiquitin-specific protease activity;0.0113085198047789!GO:0048522;positive regulation of cellular process;0.011419976990713!GO:0008180;signalosome;0.0119122115027929!GO:0006740;NADPH regeneration;0.012283110489989!GO:0006098;pentose-phosphate shunt;0.012283110489989!GO:0006007;glucose catabolic process;0.0125994690534992!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0126312099010684!GO:0046966;thyroid hormone receptor binding;0.0126954438011438!GO:0016790;thiolester hydrolase activity;0.0129408187981028!GO:0008629;induction of apoptosis by intracellular signals;0.0130501787462656!GO:0008408;3'-5' exonuclease activity;0.0130944009049097!GO:0030320;cellular monovalent inorganic anion homeostasis;0.0130944009049097!GO:0055083;monovalent inorganic anion homeostasis;0.0130944009049097!GO:0055064;chloride ion homeostasis;0.0130944009049097!GO:0030644;cellular chloride ion homeostasis;0.0130944009049097!GO:0051539;4 iron, 4 sulfur cluster binding;0.0133853166340344!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0134482234483949!GO:0016791;phosphoric monoester hydrolase activity;0.0138235221056297!GO:0004680;casein kinase activity;0.0138751587998728!GO:0004532;exoribonuclease activity;0.0138751587998728!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0138751587998728!GO:0009303;rRNA transcription;0.0141319732691997!GO:0046822;regulation of nucleocytoplasmic transport;0.014277674121658!GO:0006778;porphyrin metabolic process;0.0143978367154203!GO:0033013;tetrapyrrole metabolic process;0.0143978367154203!GO:0043414;biopolymer methylation;0.0144044832700835!GO:0046983;protein dimerization activity;0.0145268964312232!GO:0032200;telomere organization and biogenesis;0.0147720320320788!GO:0000723;telomere maintenance;0.0147720320320788!GO:0030658;transport vesicle membrane;0.01538215778979!GO:0000077;DNA damage checkpoint;0.0154277300113768!GO:0008637;apoptotic mitochondrial changes;0.0160507580189924!GO:0043601;nuclear replisome;0.0160945766450996!GO:0030894;replisome;0.0160945766450996!GO:0006378;mRNA polyadenylation;0.0165660082401842!GO:0030027;lamellipodium;0.0165887460343649!GO:0031577;spindle checkpoint;0.0165947759973437!GO:0046982;protein heterodimerization activity;0.0166967131062571!GO:0040008;regulation of growth;0.0170309581424678!GO:0006904;vesicle docking during exocytosis;0.017110413829583!GO:0006400;tRNA modification;0.017675353882635!GO:0004003;ATP-dependent DNA helicase activity;0.0177092836115718!GO:0031123;RNA 3'-end processing;0.0178214964912382!GO:0045792;negative regulation of cell size;0.0178400448294904!GO:0019318;hexose metabolic process;0.017900086141106!GO:0004221;ubiquitin thiolesterase activity;0.0181230220845167!GO:0005996;monosaccharide metabolic process;0.0181460267577411!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0183346343843559!GO:0007034;vacuolar transport;0.018696372326063!GO:0009081;branched chain family amino acid metabolic process;0.0187152175240312!GO:0005669;transcription factor TFIID complex;0.0188516523441102!GO:0000152;nuclear ubiquitin ligase complex;0.0189506051946228!GO:0043189;H4/H2A histone acetyltransferase complex;0.0190298710006717!GO:0031625;ubiquitin protein ligase binding;0.0191525731934503!GO:0031529;ruffle organization and biogenesis;0.0193111942238257!GO:0005663;DNA replication factor C complex;0.0194154327296364!GO:0003955;NAD(P)H dehydrogenase (quinone) activity;0.0196862413604495!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0199594138725856!GO:0006270;DNA replication initiation;0.0200233857992193!GO:0043433;negative regulation of transcription factor activity;0.0205223115516813!GO:0000178;exosome (RNase complex);0.0209704827959791!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0210508384100571!GO:0007021;tubulin folding;0.0210851750512503!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0210949927868091!GO:0008287;protein serine/threonine phosphatase complex;0.0214567173295078!GO:0030308;negative regulation of cell growth;0.0218276476680808!GO:0008017;microtubule binding;0.0220297271348648!GO:0000725;recombinational repair;0.0220297271348648!GO:0000724;double-strand break repair via homologous recombination;0.0220297271348648!GO:0006779;porphyrin biosynthetic process;0.0230008986285617!GO:0033014;tetrapyrrole biosynthetic process;0.0230008986285617!GO:0051053;negative regulation of DNA metabolic process;0.023207563896748!GO:0031323;regulation of cellular metabolic process;0.0233410937834471!GO:0051338;regulation of transferase activity;0.0233859304253103!GO:0051128;regulation of cellular component organization and biogenesis;0.0235218435452996!GO:0006360;transcription from RNA polymerase I promoter;0.0237456253376834!GO:0000209;protein polyubiquitination;0.0240198332071057!GO:0006730;one-carbon compound metabolic process;0.0240497267874684!GO:0043154;negative regulation of caspase activity;0.0244803228051793!GO:0030119;AP-type membrane coat adaptor complex;0.0248748714406101!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0255690424663092!GO:0006979;response to oxidative stress;0.0255726588527769!GO:0006376;mRNA splice site selection;0.0256348705333437!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0256348705333437!GO:0042168;heme metabolic process;0.0257347098601558!GO:0007346;regulation of progression through mitotic cell cycle;0.0259141364495409!GO:0030660;Golgi-associated vesicle membrane;0.0259141364495409!GO:0006417;regulation of translation;0.0260277288460913!GO:0030496;midbody;0.0265864527375141!GO:0032507;maintenance of cellular protein localization;0.0271271827353009!GO:0030659;cytoplasmic vesicle membrane;0.0273076481546834!GO:0016301;kinase activity;0.0274334140564517!GO:0003923;GPI-anchor transamidase activity;0.02765924618392!GO:0016255;attachment of GPI anchor to protein;0.02765924618392!GO:0042765;GPI-anchor transamidase complex;0.02765924618392!GO:0008538;proteasome activator activity;0.0278324234516111!GO:0030134;ER to Golgi transport vesicle;0.028269902190414!GO:0006354;RNA elongation;0.0293459854305915!GO:0003702;RNA polymerase II transcription factor activity;0.0300400812934234!GO:0006769;nicotinamide metabolic process;0.0310013835114452!GO:0004300;enoyl-CoA hydratase activity;0.0310128175346774!GO:0030503;regulation of cell redox homeostasis;0.0310128175346774!GO:0050790;regulation of catalytic activity;0.0311030995401338!GO:0006643;membrane lipid metabolic process;0.0312086747865971!GO:0022411;cellular component disassembly;0.0314894458150868!GO:0040029;regulation of gene expression, epigenetic;0.0317907968329208!GO:0000097;sulfur amino acid biosynthetic process;0.0319520730348762!GO:0035267;NuA4 histone acetyltransferase complex;0.0321887877029269!GO:0051059;NF-kappaB binding;0.0324329958337899!GO:0042026;protein refolding;0.0328637525150051!GO:0044450;microtubule organizing center part;0.0329313117052425!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0329985666412001!GO:0019377;glycolipid catabolic process;0.0335727756878438!GO:0030131;clathrin adaptor complex;0.0336994552052278!GO:0043549;regulation of kinase activity;0.0340941019576083!GO:0030125;clathrin vesicle coat;0.0342017782174628!GO:0030665;clathrin coated vesicle membrane;0.0342017782174628!GO:0005774;vacuolar membrane;0.0342017782174628!GO:0016584;nucleosome positioning;0.0342017782174628!GO:0047485;protein N-terminus binding;0.034522962076738!GO:0033673;negative regulation of kinase activity;0.0347013000261781!GO:0006469;negative regulation of protein kinase activity;0.0347013000261781!GO:0044454;nuclear chromosome part;0.0350669763151708!GO:0006739;NADP metabolic process;0.0351009487577772!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0351472420676643!GO:0001726;ruffle;0.0352038947788219!GO:0007040;lysosome organization and biogenesis;0.0359876245826848!GO:0000792;heterochromatin;0.0360815593439001!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0363932207896023!GO:0022415;viral reproductive process;0.0364846110496443!GO:0006066;alcohol metabolic process;0.0367283795105738!GO:0005680;anaphase-promoting complex;0.0367317682050264!GO:0005784;translocon complex;0.0368321161678857!GO:0043094;metabolic compound salvage;0.0368790126723141!GO:0012506;vesicle membrane;0.037581707016741!GO:0007030;Golgi organization and biogenesis;0.0376147058815155!GO:0008426;protein kinase C inhibitor activity;0.0379086225499155!GO:0033559;unsaturated fatty acid metabolic process;0.0379974723187207!GO:0006636;unsaturated fatty acid biosynthetic process;0.0379974723187207!GO:0009124;nucleoside monophosphate biosynthetic process;0.0380997448827156!GO:0009123;nucleoside monophosphate metabolic process;0.0380997448827156!GO:0051348;negative regulation of transferase activity;0.0386165343628516!GO:0048146;positive regulation of fibroblast proliferation;0.0397470233820908!GO:0030518;steroid hormone receptor signaling pathway;0.0401017701159646!GO:0043130;ubiquitin binding;0.0404200863859344!GO:0032182;small conjugating protein binding;0.0404200863859344!GO:0016615;malate dehydrogenase activity;0.0405150466315329!GO:0030127;COPII vesicle coat;0.040542229657651!GO:0012507;ER to Golgi transport vesicle membrane;0.040542229657651!GO:0006783;heme biosynthetic process;0.0412113399264454!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0413711244763775!GO:0010257;NADH dehydrogenase complex assembly;0.0413711244763775!GO:0033108;mitochondrial respiratory chain complex assembly;0.0413711244763775!GO:0008320;protein transmembrane transporter activity;0.041406060416441!GO:0006984;ER-nuclear signaling pathway;0.0414895854225678!GO:0019206;nucleoside kinase activity;0.0414895854225678!GO:0019362;pyridine nucleotide metabolic process;0.0414943899259938!GO:0044433;cytoplasmic vesicle part;0.0421515564071427!GO:0000781;chromosome, telomeric region;0.0425441997800215!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0425441997800215!GO:0050681;androgen receptor binding;0.0427748195179636!GO:0032039;integrator complex;0.04344738404683!GO:0017134;fibroblast growth factor binding;0.0435649046933988!GO:0004523;ribonuclease H activity;0.0435649046933988!GO:0008601;protein phosphatase type 2A regulator activity;0.0435649046933988!GO:0042364;water-soluble vitamin biosynthetic process;0.0435649046933988!GO:0043174;nucleoside salvage;0.0436403957467675!GO:0006166;purine ribonucleoside salvage;0.0436403957467675!GO:0043101;purine salvage;0.0436403957467675!GO:0000123;histone acetyltransferase complex;0.0438213551276285!GO:0000030;mannosyltransferase activity;0.044653900381517!GO:0006665;sphingolipid metabolic process;0.044653900381517!GO:0000159;protein phosphatase type 2A complex;0.0448141007866966!GO:0006541;glutamine metabolic process;0.0449580137572209!GO:0000305;response to oxygen radical;0.0449580137572209!GO:0008276;protein methyltransferase activity;0.0450043938563581!GO:0000175;3'-5'-exoribonuclease activity;0.0450043938563581!GO:0032153;cell division site;0.0451973984022517!GO:0032155;cell division site part;0.0451973984022517!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0454594280634436!GO:0008097;5S rRNA binding;0.0456379167157299!GO:0005856;cytoskeleton;0.0456872724297517!GO:0007041;lysosomal transport;0.0457288000449932!GO:0045893;positive regulation of transcription, DNA-dependent;0.0461634203224653!GO:0003985;acetyl-CoA C-acetyltransferase activity;0.0461634203224653!GO:0000726;non-recombinational repair;0.0464645480690679!GO:0045926;negative regulation of growth;0.0465714179314244!GO:0022884;macromolecule transmembrane transporter activity;0.0466767507199462!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0466767507199462!GO:0006897;endocytosis;0.0476284552525599!GO:0010324;membrane invagination;0.0476284552525599!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0486330202514312!GO:0005765;lysosomal membrane;0.0486574644076762!GO:0001666;response to hypoxia;0.0486649099039253!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0486649099039253!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0486649099039253!GO:0001836;release of cytochrome c from mitochondria;0.0486905217933075!GO:0030911;TPR domain binding;0.0486905217933075!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0487280446635373!GO:0006118;electron transport;0.0488733252095872!GO:0006458;'de novo' protein folding;0.0498739621267511!GO:0051084;'de novo' posttranslational protein folding;0.0498739621267511 | |||
|sample_id=10490 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=prostate | |||
|top_motifs=NFY{A,B,C}:1.24313920614;PITX1..3:1.2244178812;NKX6-1,2:1.15012476915;ELK1,4_GABP{A,B1}:1.11863819333;E2F1..5:1.11404411183;NRF1:1.09024138291;NKX2-1,4:0.979551183366;LMO2:0.961543763012;MYB:0.917046792091;SNAI1..3:0.903841051238;FOX{I1,J2}:0.802827326259;ZNF143:0.773771010313;ZEB1:0.766543216871;POU1F1:0.761182365086;SP1:0.753172934619;FOXQ1:0.74751109289;bHLH_family:0.707143777683;HOX{A4,D4}:0.626519342621;YY1:0.587812031415;AIRE:0.582775743307;TFDP1:0.581561306467;NFE2L2:0.574123225123;CRX:0.554608347317;MYOD1:0.54787152917;HOX{A5,B5}:0.535895504767;LHX3,4:0.518471043272;NKX3-1:0.512135912796;ESRRA:0.500505713363;TEF:0.492242962348;VSX1,2:0.48934666544;PBX1:0.47970088629;NKX2-2,8:0.471763209586;XCPE1{core}:0.453480664582;TEAD1:0.450371987865;STAT1,3:0.422341356003;ZBTB16:0.394971400182;NFE2:0.337288376113;NR6A1:0.326577177719;PPARG:0.281230342894;NKX2-3_NKX2-5:0.268844093449;STAT5{A,B}:0.240740451633;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.237954896906;HNF1A:0.226947915467;FOXD3:0.22365819669;PDX1:0.199754605949;ZIC1..3:0.188468512295;ZFP161:0.173196014137;HOX{A6,A7,B6,B7}:0.159090789585;RBPJ:0.152057621891;STAT2,4,6:0.125430678823;TFAP2B:0.117244280007;BACH2:0.112533066093;IKZF2:0.111843647635;HSF1,2:0.105624054838;CDC5L:0.0721476272947;FOSL2:0.0598767114836;POU5F1:0.0549942102613;FOS_FOS{B,L1}_JUN{B,D}:0.0517098278296;PAX1,9:0.0398123290088;ZNF423:0.0350077231141;FOXM1:0.0334267723222;FOXP1:0.0324555329021;CEBPA,B_DDIT3:0.0192309733756;CDX1,2,4:0.0189677667308;NFE2L1:0.0149839694944;HES1:0.00405959123306;TP53:-0.00303370920877;HIF1A:-0.00588988248895;ONECUT1,2:-0.00862859025691;EVI1:-0.0286064676692;GFI1:-0.0312479010994;UFEwm:-0.0379536233992;CREB1:-0.0404842166249;RFX2..5_RFXANK_RFXAP:-0.0431272882619;NANOG:-0.0464245328931;MTF1:-0.0581534638715;AHR_ARNT_ARNT2:-0.0598514905364;PRRX1,2:-0.0632255185996;POU2F1..3:-0.0843785293818;ARID5B:-0.0891722590717;ATF5_CREB3:-0.0891870663536;RXR{A,B,G}:-0.0920900009165;NKX3-2:-0.0948930194757;PAX5:-0.0988609287632;EN1,2:-0.110999819106;BREu{core}:-0.126203979483;ALX4:-0.12910119868;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.129401221344;OCT4_SOX2{dimer}:-0.14934038231;ZBTB6:-0.168958214482;TLX2:-0.171982462743;PAX8:-0.180869696102;FOXL1:-0.181514616052;ADNP_IRX_SIX_ZHX:-0.182567290837;NR5A1,2:-0.187866790458;NFKB1_REL_RELA:-0.193231849797;ZNF384:-0.195075277107;SOX17:-0.207181141255;HNF4A_NR2F1,2:-0.208154735812;HBP1_HMGB_SSRP1_UBTF:-0.208326577219;FOXN1:-0.211065979626;HLF:-0.229067299057;RREB1:-0.229840340129;GATA6:-0.237467681096;RFX1:-0.243644676522;ATF4:-0.251150299617;RORA:-0.254092848075;TAL1_TCF{3,4,12}:-0.259494152699;FOX{F1,F2,J1}:-0.267599107798;TBX4,5:-0.283933505311;ESR1:-0.286272408046;CUX2:-0.293154369729;ZNF148:-0.293282799465;PAX2:-0.295927374886;ELF1,2,4:-0.302232683545;REST:-0.302505551896;EGR1..3:-0.304642073226;PAX6:-0.30638642352;GFI1B:-0.307378471989;MYBL2:-0.309119374585;HIC1:-0.334576656493;EBF1:-0.348541363283;DBP:-0.348888115121;TFAP2{A,C}:-0.364293769726;DMAP1_NCOR{1,2}_SMARC:-0.367269499327;MEF2{A,B,C,D}:-0.375342133661;IRF7:-0.384686604004;IKZF1:-0.388394388737;HOXA9_MEIS1:-0.407258900937;SOX{8,9,10}:-0.418415315046;RXRA_VDR{dimer}:-0.431179064426;TOPORS:-0.442083235954;FOXP3:-0.461609693643;PAX4:-0.468318757342;GCM1,2:-0.473416327048;LEF1_TCF7_TCF7L1,2:-0.483954608073;FOX{D1,D2}:-0.489846578036;PAX3,7:-0.496328349012;FOXO1,3,4:-0.506580348184;TBP:-0.508267605943;SPIB:-0.509647433196;GTF2A1,2:-0.522161465768;GZF1:-0.523785330088;RUNX1..3:-0.524697265994;HMGA1,2:-0.538698377874;NR3C1:-0.558212715763;JUN:-0.558246197568;TFCP2:-0.559701154968;PATZ1:-0.583512455175;IRF1,2:-0.600779133596;SREBF1,2:-0.601855902925;EP300:-0.608701889743;TLX1..3_NFIC{dimer}:-0.611295294694;SOX2:-0.616983021142;HAND1,2:-0.620103418399;ETS1,2:-0.630677723512;POU6F1:-0.634674501764;KLF4:-0.641410205299;GTF2I:-0.645872908904;POU3F1..4:-0.650291210277;ALX1:-0.656426516253;SOX5:-0.657382816546;MED-1{core}:-0.66973573583;NR1H4:-0.672286826102;FOXA2:-0.675363743652;SPI1:-0.681339839354;SRF:-0.699307133061;GLI1..3:-0.711627720267;MTE{core}:-0.734848913338;MAZ:-0.761599352676;NFIL3:-0.764265668479;ATF2:-0.792390664542;SPZ1:-0.844792854197;PRDM1:-0.853439889675;MYFfamily:-0.869970003328;AR:-0.898341614575;GATA4:-0.939443973701;NFIX:-0.94859307924;T:-0.98829855416;MAFB:-0.993218300344;XBP1:-1.0910329479;NANOG{mouse}:-1.1092110162;BPTF:-1.10925666914;ATF6:-1.16176368588;MZF1:-1.18514120762;NHLH1,2:-1.19709838935;TGIF1:-1.25627854433;NFATC1..3:-1.37012709718;TFAP4:-1.37926634017;ZNF238:-1.54008459195;HMX1:-2.25497905463;SMAD1..7,9:-2.61273413308 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10490-107B4;search_select_hide=table117:FF:10490-107B4 | |||
}} | }} |
Latest revision as of 14:27, 3 June 2020
Name: | prostate cancer cell line:DU145 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11260 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11260
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11260
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.662 |
10 | 10 | 0.744 |
100 | 100 | 0.0908 |
101 | 101 | 0.237 |
102 | 102 | 0.552 |
103 | 103 | 0.84 |
104 | 104 | 0.411 |
105 | 105 | 0.818 |
106 | 106 | 2.98872e-5 |
107 | 107 | 0.152 |
108 | 108 | 0.653 |
109 | 109 | 0.249 |
11 | 11 | 0.387 |
110 | 110 | 0.697 |
111 | 111 | 0.891 |
112 | 112 | 0.056 |
113 | 113 | 0.0111 |
114 | 114 | 0.191 |
115 | 115 | 0.718 |
116 | 116 | 0.777 |
117 | 117 | 0.576 |
118 | 118 | 0.934 |
119 | 119 | 0.121 |
12 | 12 | 0.794 |
120 | 120 | 0.459 |
121 | 121 | 0.708 |
122 | 122 | 0.868 |
123 | 123 | 0.163 |
124 | 124 | 0.0505 |
125 | 125 | 0.271 |
126 | 126 | 0.605 |
127 | 127 | 0.539 |
128 | 128 | 3.26293e-4 |
129 | 129 | 0.338 |
13 | 13 | 0.0582 |
130 | 130 | 0.615 |
131 | 131 | 0.102 |
132 | 132 | 0.709 |
133 | 133 | 0.147 |
134 | 134 | 0.737 |
135 | 135 | 0.0129 |
136 | 136 | 0.0153 |
137 | 137 | 0.239 |
138 | 138 | 0.974 |
139 | 139 | 0.0061 |
14 | 14 | 0.642 |
140 | 140 | 0.00297 |
141 | 141 | 0.529 |
142 | 142 | 0.632 |
143 | 143 | 0.00485 |
144 | 144 | 0.305 |
145 | 145 | 0.392 |
146 | 146 | 0.331 |
147 | 147 | 0.661 |
148 | 148 | 0.509 |
149 | 149 | 0.0574 |
15 | 15 | 0.411 |
150 | 150 | 0.497 |
151 | 151 | 0.195 |
152 | 152 | 0.492 |
153 | 153 | 0.158 |
154 | 154 | 0.448 |
155 | 155 | 0.791 |
156 | 156 | 0.972 |
157 | 157 | 0.32 |
158 | 158 | 0.357 |
159 | 159 | 0.389 |
16 | 16 | 0.631 |
160 | 160 | 0.5 |
161 | 161 | 0.808 |
162 | 162 | 0.379 |
163 | 163 | 0.936 |
164 | 164 | 0.401 |
165 | 165 | 0.931 |
166 | 166 | 0.526 |
167 | 167 | 0.896 |
168 | 168 | 0.232 |
169 | 169 | 0.422 |
17 | 17 | 0.262 |
18 | 18 | 0.054 |
19 | 19 | 0.0744 |
2 | 2 | 0.315 |
20 | 20 | 0.048 |
21 | 21 | 0.296 |
22 | 22 | 0.247 |
23 | 23 | 0.0129 |
24 | 24 | 0.992 |
25 | 25 | 0.556 |
26 | 26 | 0.763 |
27 | 27 | 0.0964 |
28 | 28 | 0.598 |
29 | 29 | 0.805 |
3 | 3 | 0.291 |
30 | 30 | 0.991 |
31 | 31 | 0.205 |
32 | 32 | 0.0612 |
33 | 33 | 0.261 |
34 | 34 | 0.483 |
35 | 35 | 0.14 |
36 | 36 | 0.193 |
37 | 37 | 0.708 |
38 | 38 | 0.863 |
39 | 39 | 0.683 |
4 | 4 | 0.867 |
40 | 40 | 0.0183 |
41 | 41 | 0.0538 |
42 | 42 | 0.57 |
43 | 43 | 0.122 |
44 | 44 | 0.767 |
45 | 45 | 0.419 |
46 | 46 | 0.086 |
47 | 47 | 0.811 |
48 | 48 | 0.99 |
49 | 49 | 0.136 |
5 | 5 | 0.103 |
50 | 50 | 0.571 |
51 | 51 | 0.317 |
52 | 52 | 0.14 |
53 | 53 | 0.166 |
54 | 54 | 0.446 |
55 | 55 | 0.23 |
56 | 56 | 0.45 |
57 | 57 | 0.633 |
58 | 58 | 0.199 |
59 | 59 | 0.118 |
6 | 6 | 0.642 |
60 | 60 | 0.0517 |
61 | 61 | 0.276 |
62 | 62 | 0.0788 |
63 | 63 | 0.802 |
64 | 64 | 0.7 |
65 | 65 | 0.132 |
66 | 66 | 0.0628 |
67 | 67 | 0.985 |
68 | 68 | 0.536 |
69 | 69 | 0.469 |
7 | 7 | 0.863 |
70 | 70 | 0.0264 |
71 | 71 | 0.553 |
72 | 72 | 0.218 |
73 | 73 | 0.986 |
74 | 74 | 0.254 |
75 | 75 | 0.826 |
76 | 76 | 0.608 |
77 | 77 | 0.497 |
78 | 78 | 0.646 |
79 | 79 | 0.0914 |
8 | 8 | 0.385 |
80 | 80 | 0.0825 |
81 | 81 | 0.206 |
82 | 82 | 0.0065 |
83 | 83 | 0.36 |
84 | 84 | 0.911 |
85 | 85 | 0.00877 |
86 | 86 | 0.494 |
87 | 87 | 0.161 |
88 | 88 | 0.731 |
89 | 89 | 0.255 |
9 | 9 | 0.0694 |
90 | 90 | 0.399 |
91 | 91 | 0.0785 |
92 | 92 | 0.0625 |
93 | 93 | 0.456 |
94 | 94 | 0.0178 |
95 | 95 | 0.233 |
96 | 96 | 0.2 |
97 | 97 | 0.798 |
98 | 98 | 0.228 |
99 | 99 | 0.975 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11260
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101332 DU-145 cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
7 (disease of anatomical entity)
305 (carcinoma)
UBERON: Anatomy
0000468 (multi-cellular organism)
0002367 (prostate gland)
0005156 (reproductive structure)
0004119 (endoderm-derived structure)
0000062 (organ)
0004120 (mesoderm-derived structure)
0000077 (mixed endoderm/mesoderm-derived structure)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000990 (reproductive system)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0002530 (gland)
0010147 (male accessory sex gland)
0010317 (germ layer / neural crest derived structure)
0003937 (sex gland)
0005399 (male reproductive gland)
0003101 (male organism)
0000079 (male reproductive system)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100297 (carcinoma cell line sample)
0101120 (epithelial cell line sample)
0101019 (prostate gland cell line sample)
0101033 (prostate cancer cell line sample)
0101332 (DU-145 cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
UBERON:0002532 (epiblast (generic))
UBERON:0006595 (presumptive endoderm)
UBERON:0006603 (presumptive mesoderm)
UBERON:0009847 (prostate field)
UBERON:0003353 (epithelium of hindgut)
UBERON:0010316 (germ layer / neural crest)