FF:10712-109I1: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005930 | ||
| | |DRA_sample_Accession_RNASeq=RNA-Seq@SAMD00005930 | ||
| | |accession_numbers=CAGE;DRX007902;DRR008774;DRZ000199;DRZ001584;DRZ011549;DRZ012934 | ||
| | |accession_numbers_RNASeq=RNA-Seq;DRX057136;DRR062895;DRZ007971 | ||
|ancestors_in_anatomy_facet= | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000542,CL:0000219,CL:0000738,CL:0002087,CL:0002242,CL:0000255,CL:0000084 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0103681,FF:0101014 | |||
| | |comment= | ||
| | |created_by= | ||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
| | |expression_enrichment_score=chr6:391743..391759,+!p1@IRF4!2.63!421.93!IRF4;;chr1:3569072..3569093,+!p1@TP73!2.51!324.93!TP73;;chr20:62680984..62680999,-!p1@SOX18!2.11!167.20!SOX18;;chr1:3598871..3598890,+!p11@TP73!2.04!109.89!TP73;;chr1:25291475..25291511,-!p2@RUNX3!1.92!83.07!RUNX3;;chr18:55102598..55102623,+!p1@ONECUT2!1.92!83.07!ONECUT2;;chr1:25256756..25256774,-!p1@RUNX3!1.91!146.95!RUNX3;;chr14:75988831..75988847,+!p2@BATF!1.89!75.97!BATF;;chr10:104155659..104155676,+!p4@NFKB2!1.81!78.34!NFKB2;;chr13:28494130..28494168,+!p1@PDX1!1.79!61.25!PDX1;;chr19:50922187..50922204,+!p1@SPIB!1.70!48.90!SPIB;;chr18:55102628..55102646,+!p2@ONECUT2!1.65!43.90!ONECUT2;;chr15:57401426..57401459,+!p20@TCF12!1.63!41.80!TCF12;;chr2:231090471..231090504,+!p2@SP140!1.63!41.27!SP140;;chr6:135502408..135502459,+!p2@MYB!1.60!44.69!MYB;;chr2:231090433..231090469,+!p1@SP140!1.60!39.17!SP140;;chr2:176969228..176969260,+!p1@HOXD11!1.60!38.38!HOXD11;;chr19:36204309..36204335,+!p1@ZBTB32!1.56!34.96!ZBTB32;;chr6:135502501..135502546,+!p1@MYB!1.55!41.27!MYB;;chr14:75988771..75988826,+!p1@BATF!1.54!44.43!BATF;;chr7:128577972..128578047,+!p1@IRF5!1.51!48.90!IRF5;;chr20:50159198..50159299,-!p1@NFATC2!1.50!44.69!NFATC2;;chr10:104155680..104155687,+!p6@NFKB2!1.49!29.97!NFKB2;;chr3:111314186..111314204,-!p1@ZBED2!1.48!29.18!ZBED2;;chr8:11561684..11561751,+!p1@GATA4!1.46!27.87!GATA4;;chr2:176969179..176969226,+!p2@HOXD11!1.41!24.97!HOXD11;;chr3:128212033..128212051,-!p1@GATA2!1.40!24.19!GATA2;;chr1:212873267..212873332,-!p1@BATF3!1.39!31.55!BATF3;;chr17:40441354..40441410,+!p2@STAT5A!1.37!22.35!STAT5A;;chr1:212873162..212873188,-!p3@BATF3!1.35!21.29!BATF3;;chr1:3569135..3569150,+!p3@TP73!1.34!21.03!TP73;;chr15:60884706..60884743,-!p1@RORA!1.32!99.90!RORA;;chr6:106546808..106546833,+!p3@PRDM1!1.32!24.97!PRDM1;;chr12:124968655..124968666,-!p48@NCOR2!1.32!19.98!NCOR2;;chr5:88178983..88179012,-!p1@MEF2C!1.30!142.22!MEF2C;;chr10:104155480..104155534,+!p2@NFKB2!1.28!115.93!NFKB2;;chr6:106534192..106534224,+!p1@PRDM1!1.27!48.90!PRDM1;;chr7:50348268..50348366,+!p4@IKZF1!1.27!17.61!IKZF1;;chr12:124968706..124968748,-!p18@NCOR2!1.26!17.35!NCOR2;;chr14:35873947..35873965,-!p1@NFKBIA!1.24!1008.44!NFKBIA;;chr5:137804484..137804498,+!p2@EGR1!1.24!65.20!EGR1;;chr17:38020392..38020477,-!p1@IKZF3!1.24!16.30!IKZF3;;chr2:61108808..61108821,+!p3@REL!1.22!19.72!REL;;chr1:3568889..3568900,+!p7@TP73!1.22!15.51!TP73;;chr9:2015335..2015370,+!p1@SMARCA2!1.20!177.71!SMARCA2;;chr5:133450365..133450444,+!p1@TCF7!1.20!67.56!TCF7;;chr12:52445218..52445237,+!p1@NR4A1!1.19!178.50!NR4A1;;chr19:42636586..42636607,-!p1@POU2F2!1.19!39.43!POU2F2;;chr4:26322267..26322334,+!p3@RBPJ!1.18!34.18!RBPJ;;chr3:101546827..101546847,+!p2@NFKBIZ!1.18!19.72!NFKBIZ;;chr6:21597765..21597779,+!p2@SOX4!1.17!110.94!SOX4;;chr3:128206762..128206781,-!p2@GATA2!1.17!84.39!GATA2;;chr6:100912785..100912822,-!p1@SIM1!1.17!13.93!SIM1;;chr1:38512457..38512474,-!p1@POU3F1!1.16!14.72!POU3F1;;chr3:18486354..18486377,-!p2@SATB1!1.15!16.56!SATB1;;chrY:21906594..21906622,-!p1@KDM5D!1.15!13.14!KDM5D;;chr2:97202480..97202499,+!p1@ARID5A!1.14!127.50!ARID5A;;chr1:3568870..3568881,+!p5@TP73!1.14!12.88!TP73;;chr2:61108695..61108753,+!p1@REL!1.13!85.44!REL;;chr10:104154415..104154434,+!p5@NFKB2!1.11!11.83!NFKB2;;chr5:88179017..88179046,-!p2@MEF2C!1.10!46.27!MEF2C;;chr1:3569101..3569115,+!p2@TP73!1.10!11.57!TP73;;chr2:8822176..8822196,+!p1@ID2!1.09!1571.01!ID2;;chr1:212873084..212873137,-!p2@BATF3!1.09!11.30!BATF3;;chr2:176972000..176972025,+!p4@HOXD11!1.08!11.04!HOXD11;;chr15:76629123..76629151,+!p1@ISL2!1.07!12.09!ISL2;;chr2:61108878..61108891,+!p5@REL!1.07!10.78!REL;;chr5:137801160..137801176,+!p1@EGR1!1.06!1044.71!EGR1;;chr7:50344289..50344323,+!p1@IKZF1!1.06!10.52!IKZF1;;chr10:104155455..104155479,+!p1@NFKB2!1.05!150.37!NFKB2;;chr11:47400078..47400106,-!p1@SPI1!1.05!10.25!SPI1;;chr1:3568928..3568946,+!p4@TP73!1.05!10.25!TP73;;chr6:106534230..106534254,+!p2@PRDM1!1.04!25.50!PRDM1;;chr2:185463247..185463263,+!p1@ZNF804A!1.04!17.88!ZNF804A;;chr4:26324474..26324501,+!p16@RBPJ!1.04!9.99!RBPJ;;chr4:57522513..57522548,-!p4@HOPX!1.03!9.73!HOPX;;chr6:106546834..106546850,+!p4@PRDM1!1.03!9.73!PRDM1;;chr17:40440359..40440386,+!p4@STAT5A!1.03!9.73!STAT5A;;chr6:21593973..21593988,+!p1@SOX4!1.02!345.17!SOX4;;chr12:48298785..48298828,-!p1@VDR!1.01!49.69!VDR;;chr13:28494109..28494122,+!p2@PDX1!1.01!9.20!PDX1;;chr1:3568961..3568973,+!p6@TP73!1.01!9.20!TP73;;chr6:135502472..135502489,+!p3@MYB!1.00!8.94!MYB;;chr12:24715376..24715432,-!p1@SOX5!0.99!11.30!SOX5;;chr9:2015306..2015323,+!p3@SMARCA2!0.98!22.87!SMARCA2;;chr19:45252008..45252024,+!p2@BCL3!0.97!28.39!BCL3;;chr12:103351444..103351461,+!p1@ASCL1!0.97!8.41!ASCL1;;chr6:42419649..42419673,-!p3@TRERF1!0.96!14.20!TRERF1;;chr17:45810594..45810608,+!p1@TBX21!0.95!7.89!TBX21;;chr6:20402102..20402152,+!p1@E2F3!0.94!33.12!E2F3;;chr7:50344251..50344288,+!p3@IKZF1!0.94!7.62!IKZF1;;chr12:48276548..48276564,-!p3@VDR!0.94!7.62!VDR;;chr2:145188354..145188371,-!p34@ZEB2!0.94!7.62!ZEB2;;chr14: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| ||
|ffid_belonging_in_development=CL:0000134,CL:0000051 | |||
| | |||
| | |||
| | |||
| | |||
| | |||
| | |||
| | |||
| | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
Line 66: | Line 42: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/hairy%2520cell%2520leukemia%2520cell%2520line%253aMo.CNhs11843.10712-109I1.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/hairy%2520cell%2520leukemia%2520cell%2520line%253aMo.CNhs11843.10712-109I1.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/hairy%2520cell%2520leukemia%2520cell%2520line%253aMo.CNhs11843.10712-109I1.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/hairy%2520cell%2520leukemia%2520cell%2520line%253aMo.CNhs11843.10712-109I1.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/hairy%2520cell%2520leukemia%2520cell%2520line%253aMo.CNhs11843.10712-109I1.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10712-109I1 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0101014 | |||
|is_obsolete= | |||
|library_id=CNhs11843 | |||
|library_id_phase_based=2:CNhs11843 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10712 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10712 | |||
|name=hairy cell leukemia cell line:Mo | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11843,LSID829,release010,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.0506823072663195,0,0,0,0,0.151763952499926,0.252528295789208,-0.0913428865092769,0.413973557832821,0,0,0,0.0094536644328004,0,0,0,0,0,0,0.101364614532639,0.101364614532639,0,0.0992052854407801,0,0,0,0,0.101364614532639,0.39383771189075,0,0,0.537328511341224,0,0,0,0,0,0,0,0,0,0,0,0,-0.0541545111176061,0.264444871925393,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0.183490411696814,0,-0.0210781792832569,0,0.640922313754528,0,0,0.00402098731954179,0,0,0,0,0,0,0,0,0.101364614532639,0,0.364445320695129,0,0,0.101364614532639,0,0,0,0,0.0506823072663195,0,0,0,0,0,-0.552571649267773,0,0,0,0.267878156767643,0.47513575539886,0.0506823072663195,0,0.091745205848407,0,0.0854550604591072,0.270465433136476,0,0,0,0,0,0,0.101364614532639,0,0,0,0,0,0,0,0,0,0,-0.0456912866561416,0.183490411696814,0,0,0.0486500719641351,0.0751868937371949,0,0,0.293461639492675,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0.491795608158807,0.0854550604591072,0,0,0.252528295789208,0,0.101364614532639,0,0,0,0,0,0,-0.247178875285564,0.00642648251087575,-0.37272160421937,-0.143515142523472,0,0,-0.200603747668067,0,0,0,0,0.183490411696814,0,0.101364614532639,0.101364614532639,0,0.0553705447442489,0,-0.0504125515893149,0.0506823072663195,0,0,0,0,0.313062029721483,0,-0.0182170698563537,-0.0683442610773682,0,0.101364614532639,0,0,-0.168876054801686,0,0.49765477682615,-0.0827201683234173,0,-0.553849713700637,-0.055712496781182,0,0,0.0506823072663195,-0.565597432146815,-0.65393359269776,0,0,-0.121779851751874,0.0645481855187445,0,0.183490411696814,-0.391044581551635,0,-0.123593057756177,-0.0421447518227773,0,0.472104608334967,0.101364614532639,0,0,0,0,0,0,0,0.183490411696814,0,0,-0.0574934668214365,0.263157553449751,0.0709546336950604,0,0,0,-0.0883895439192649,0,0,-0.373286155956567,-0.0861415647880472,0,0.218240602313596,0,0.189405881148894,-0.188110270372368,-0.190703806712968,0.346543684931291,-0.147401849371139,-0.189981719549847,0,0.0246235020547956,0.0280172243369202,-0.0280652873405592,-0.0948384078287188,0.057771275818433,-1.2314085082871,0.142876283790417,0,0,0,-0.205371952854461,0,0,-0.490114714476774,-0.231479718130778,-0.620305129209391,-0.0457782088327468,-0.135500604985687,-0.0959475319715257,0.257047582889052,-0.273946041199781,-0.00280254736834567,-0.295308177009096,-0.0482027130012503,0.312081982586312,0,0.0867078213229727,-0.332561428624315,0.0781917007881,0.00119634687435355,0.00781814634782663,0.0330203534552705,0,0.484886167920138,0.0326136704252435,0.312081982586312,0,0.269190625933509,0,0,0.312081982586312,0,0,-0.0123906622329899,-0.356001731333353,0.258940046603263,0,-0.0337433101882732,-0.0143770380109263,-0.070610741111083,0,-0.106029998400992,0.251179916872202,0.0663711683338364,-0.292633804596236,0,0.060051114970697,-0.0514818103127662,-0.164990696339003,0.766781099100906,0.394903851671182,0.0838179196752008,-0.118234501621606,0.0433295223675332,-0.37777082569578,0,-0.0881268324752877,-0.101143173547309,-0.700054338821567,-0.367416149035212,0,-0.583529904229572,0,-0.382530929171532,0,-0.174173539849088,0,0.254166110422982,0.0781005091466505,0.81809344411531,0.0572659546274319,0,-0.128069024749953,-0.376961898679527,0,-0.230264624576867,-0.0418423631493412,0,0.341428524824168,-0.697695966512583,-0.160968120598269,-0.0883071494128752,0,-0.606589746692843,0,0,-0.0654014792062987,0.32429579661858,0.101364614532639,0.0397596383144512,-0.0190567640846767,-0.112420433036487,-0.0146064589022953,0,0,-0.462209926295911,0,0,-0.504563449285392,-0.0636048451378017,-0.619783323958633,0.306445492896213,-0.009920314536802,-0.108622809454255,0,0,0.186917554729953,0,-0.419203791396523,0,0,-0.12361714870422,-0.015263498457494,0,0.205584519547224,0.101364614532639,0,0.0984180562263315,0,0,0,0,0,-0.0254029017583575,0.00790574698774016,-0.354833330216448,0.183490411696814,-0.0230845169104006,0,0,0,0,0,0,0,0,0.0548213604018453,-0.056253955557224,0.0604729960203933,0,0,0,0,0.195445636540972,-0.101871947562085,0,0.18021927608868,0,0.279885917191484,0,0,0.0152236247434274,0,0,0,0.182222660347565,-0.057730457053664,0.113326643042183,0,0,0,0.439566251740313,0,0,0,0,-0.125268974226149,0,0,0,0,0.101091500113072,0.0197827349857973,0,-0.235038276546543,-0.442974774721524,0.0334136400247129,0,0,-0.077856720093074,0,0,-0.0745465812456588,0,0.101364614532639,0.00332213485551923,0,0,0,0,0.176915734352376,0.183490411696814,0.0382137833894521,0,0,0,0,0,0,0,0,0,0,0,-0.242969595222498,0.219857925927802,0,0,0,0,0,0,0,-0.0241060230789031,0.0551702747294189,0,0,0.0506823072663195,0,0,0.101364614532639,0,0,0.407795210676553,0,0,0,0,0,0.640922313754528,0,0.183490411696814,0,0.101364614532639,0.51586513307933,0,0,-0.0938717204967005,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.021954471502809,-0.00445786441512497,0,0,0,0,0,0.252528295789208,0,-0.0913428865092769,0,0.312081982586312,0,0,0.138643922080231,0,0,0,-0.104796384789156,0,0.151763952499926,0,0.101364614532639,0,0,0,0.101364614532639,0.182222660347565,0.0506823072663195,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.641880399993095,0,-0.28720751597291,-0.0218382500411467,0,0,-0.232628352633041,0.0506823072663195,0,0,0,0,0,0.195334915212976,0.0295764201381822,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0506823072663195,0,0.183490411696814,0,0,0,0,0,0,0.015824263461231,0,0,0,0,0,0,0,0.39383771189075,0,0.500657594611583,0.00933180473211262,0,0,0,0,0.491795608158807,0,0.127750771664833,-0.283220399823148,-0.0578495885262251,0,0,0,-0.054385572482455,0.183490411696814,0,-0.0275437732970252,0,-0.0667773874189013,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0992052854407801,0,0,0,0,0,0,0,0,0,0,0,0,0.0506823072663195,0,0,0,0,0,0,0,0,0,0,0,0,0.183490411696814,0,0.411169039094447,0.0506823072663195,0,0,0,0,0,0,0.0577338425729905,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.411777139890169,0,0,0,-0.111721615124405,0,0,0,0,0,0,0,0,0.364445320695129,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.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| |||
|rna_box=109 | |||
|rna_catalog_number= | |||
|rna_concentration=1.59719 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.13 | |||
|rna_od260/280=2.08 | |||
|rna_position=I1 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=109I1 | |||
|rna_weight_ug=75.06793 | |||
|rnaseq_library_id=RDhi10079 | |||
|sample_age= | |||
|sample_category=cell lines | |||
|sample_cell_catalog=CRL-8066 | |||
|sample_cell_line=Mo | |||
|sample_cell_lot= | |||
|sample_cell_type=t cell | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=ATCC | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=hairy cell leukemia | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;3.03600062107925e-252!GO:0043227;membrane-bound organelle;4.31346462451116e-217!GO:0043231;intracellular membrane-bound organelle;1.32939307045473e-216!GO:0043226;organelle;5.16247438945374e-213!GO:0043229;intracellular organelle;2.12444304907423e-212!GO:0005737;cytoplasm;8.66369423252505e-166!GO:0044422;organelle part;1.9690611696648e-164!GO:0044446;intracellular organelle part;1.5005066934507e-162!GO:0032991;macromolecular complex;6.22239643702954e-132!GO:0044444;cytoplasmic part;7.76756125822016e-115!GO:0044237;cellular metabolic process;1.10877726616103e-107!GO:0005634;nucleus;9.53461390504848e-105!GO:0044238;primary metabolic process;1.00173565467271e-104!GO:0030529;ribonucleoprotein complex;2.67849425172221e-101!GO:0044428;nuclear part;1.93525210500468e-100!GO:0043170;macromolecule metabolic process;6.36015352667525e-100!GO:0043233;organelle lumen;1.27466711014987e-93!GO:0031974;membrane-enclosed lumen;1.27466711014987e-93!GO:0003723;RNA binding;1.76210536958624e-85!GO:0005739;mitochondrion;1.32842179253379e-79!GO:0005515;protein binding;1.33039035985149e-79!GO:0043234;protein complex;8.12851783726105e-70!GO:0006412;translation;5.10767702284384e-66!GO:0043283;biopolymer metabolic process;1.15257433827568e-65!GO:0006396;RNA processing;3.35839207301707e-64!GO:0031981;nuclear lumen;6.46907513278462e-60!GO:0005840;ribosome;4.13682226421564e-58!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.64351561606359e-58!GO:0010467;gene expression;1.88850044968142e-55!GO:0044429;mitochondrial part;7.04123180300301e-55!GO:0006259;DNA metabolic process;4.68228070840364e-54!GO:0019538;protein metabolic process;1.36205465231889e-50!GO:0044249;cellular biosynthetic process;2.09261216547172e-50!GO:0003735;structural constituent of ribosome;2.09261216547172e-50!GO:0031967;organelle envelope;4.86694855420712e-50!GO:0031975;envelope;1.27003023197673e-49!GO:0016071;mRNA metabolic process;2.01566904775273e-49!GO:0009058;biosynthetic process;3.35907413537411e-47!GO:0009059;macromolecule biosynthetic process;6.88079331121806e-47!GO:0044267;cellular protein metabolic process;1.36285256811955e-46!GO:0044260;cellular macromolecule metabolic process;2.92656619709184e-46!GO:0016043;cellular component organization and biogenesis;3.58409071689698e-46!GO:0033036;macromolecule localization;1.84114938805049e-44!GO:0008380;RNA splicing;2.05071119738111e-44!GO:0031090;organelle membrane;4.7772488705167e-44!GO:0033279;ribosomal subunit;1.18912457486124e-43!GO:0006996;organelle organization and biogenesis;4.42961457268273e-43!GO:0006397;mRNA processing;2.25992692507808e-42!GO:0015031;protein transport;7.44187215698502e-42!GO:0008104;protein localization;2.28887907320665e-40!GO:0045184;establishment of protein localization;3.74243014298903e-40!GO:0043228;non-membrane-bound organelle;3.74230075732984e-39!GO:0043232;intracellular non-membrane-bound organelle;3.74230075732984e-39!GO:0005829;cytosol;6.83310059673367e-39!GO:0005654;nucleoplasm;2.12495373031416e-38!GO:0022613;ribonucleoprotein complex biogenesis and assembly;6.38145390816169e-38!GO:0046907;intracellular transport;1.38978329040205e-37!GO:0000166;nucleotide binding;3.43174085090541e-37!GO:0003676;nucleic acid binding;1.72563025367928e-35!GO:0007049;cell cycle;4.95310848451839e-35!GO:0005740;mitochondrial envelope;1.24072462874341e-33!GO:0065003;macromolecular complex assembly;5.31703617187841e-33!GO:0005681;spliceosome;2.35530757181389e-32!GO:0019866;organelle inner membrane;6.61349854014384e-32!GO:0005830;cytosolic ribosome (sensu Eukaryota);9.12657720243493e-32!GO:0006974;response to DNA damage stimulus;1.32079925978141e-31!GO:0031966;mitochondrial membrane;2.65249400359772e-31!GO:0006886;intracellular protein transport;5.49996249175883e-31!GO:0051649;establishment of cellular localization;3.19610312807723e-30!GO:0051641;cellular localization;3.82716134686519e-30!GO:0005694;chromosome;2.3282681271945e-29!GO:0005743;mitochondrial inner membrane;3.24746909455892e-29!GO:0044451;nucleoplasm part;3.99851758403496e-29!GO:0022402;cell cycle process;2.24832103134834e-28!GO:0032553;ribonucleotide binding;2.42387247687094e-28!GO:0032555;purine ribonucleotide binding;2.42387247687094e-28!GO:0022607;cellular component assembly;4.23867705058592e-28!GO:0017076;purine nucleotide binding;1.12842170138446e-27!GO:0006281;DNA repair;2.24315486244408e-27!GO:0044445;cytosolic part;4.12700371315942e-27!GO:0016070;RNA metabolic process;5.71952030057286e-26!GO:0044427;chromosomal part;1.36868356242459e-25!GO:0005524;ATP binding;1.66118797508777e-25!GO:0016462;pyrophosphatase activity;2.09555734196921e-25!GO:0017111;nucleoside-triphosphatase activity;2.71041694984165e-25!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.00735839801686e-25!GO:0032559;adenyl ribonucleotide binding;3.19123185267019e-25!GO:0031980;mitochondrial lumen;3.33563725867792e-25!GO:0005759;mitochondrial matrix;3.33563725867792e-25!GO:0016817;hydrolase activity, acting on acid anhydrides;4.02149865921636e-25!GO:0030554;adenyl nucleotide binding;2.62188705730456e-24!GO:0051276;chromosome organization and biogenesis;2.91861173541125e-24!GO:0000278;mitotic cell cycle;9.894662810948e-24!GO:0006119;oxidative phosphorylation;7.51633902570838e-23!GO:0005730;nucleolus;8.51618462603675e-23!GO:0015935;small ribosomal subunit;1.32572810904079e-22!GO:0044455;mitochondrial membrane part;1.58920158783413e-22!GO:0015934;large ribosomal subunit;3.64237796775979e-22!GO:0016874;ligase activity;2.95494893537671e-21!GO:0022403;cell cycle phase;5.67638631761517e-21!GO:0009719;response to endogenous stimulus;7.51574630145862e-21!GO:0006915;apoptosis;7.60023300122628e-21!GO:0012501;programmed cell death;7.68090938635847e-21!GO:0022618;protein-RNA complex assembly;1.82256129696123e-20!GO:0000087;M phase of mitotic cell cycle;1.25188382944292e-19!GO:0016887;ATPase activity;1.75498623298809e-19!GO:0006325;establishment and/or maintenance of chromatin architecture;1.76594924165787e-19!GO:0007067;mitosis;2.26671366211251e-19!GO:0008219;cell death;3.99935772339893e-19!GO:0016265;death;3.99935772339893e-19!GO:0008134;transcription factor binding;4.05104049757522e-19!GO:0006260;DNA replication;4.53300557749347e-19!GO:0006323;DNA packaging;9.86103782377893e-19!GO:0042623;ATPase activity, coupled;1.33763512801214e-18!GO:0008135;translation factor activity, nucleic acid binding;2.40204001400108e-18!GO:0005746;mitochondrial respiratory chain;2.60421071679452e-18!GO:0044265;cellular macromolecule catabolic process;2.72214168154652e-18!GO:0042254;ribosome biogenesis and assembly;2.78244845824155e-18!GO:0006512;ubiquitin cycle;8.81408352450679e-18!GO:0005635;nuclear envelope;9.26096335426623e-18!GO:0043412;biopolymer modification;1.00536478980133e-17!GO:0000279;M phase;1.30338249245199e-17!GO:0006457;protein folding;2.2428328268473e-17!GO:0000502;proteasome complex (sensu Eukaryota);5.2452303424017e-17!GO:0051301;cell division;5.9592872884366e-17!GO:0005761;mitochondrial ribosome;9.60404800956869e-17!GO:0000313;organellar ribosome;9.60404800956869e-17!GO:0012505;endomembrane system;1.16728298383928e-16!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.49070052232224e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.5621576022411e-16!GO:0050136;NADH dehydrogenase (quinone) activity;3.91491498543773e-16!GO:0003954;NADH dehydrogenase activity;3.91491498543773e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.91491498543773e-16!GO:0006605;protein targeting;5.15500642005752e-16!GO:0044248;cellular catabolic process;5.17923601780172e-16!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.21023064270914e-15!GO:0009057;macromolecule catabolic process;1.74158017416588e-15!GO:0044453;nuclear membrane part;2.03313470106681e-15!GO:0000785;chromatin;3.28833660197905e-15!GO:0043285;biopolymer catabolic process;3.28833660197905e-15!GO:0006464;protein modification process;4.01523727216786e-15!GO:0051726;regulation of cell cycle;4.16495158707961e-15!GO:0016604;nuclear body;4.35366681235782e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;4.35366681235782e-15!GO:0000375;RNA splicing, via transesterification reactions;4.35366681235782e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;4.35366681235782e-15!GO:0006913;nucleocytoplasmic transport;5.04590803852279e-15!GO:0031965;nuclear membrane;5.50320854619321e-15!GO:0000074;regulation of progression through cell cycle;7.56681107956582e-15!GO:0006333;chromatin assembly or disassembly;7.7643769007831e-15!GO:0051169;nuclear transport;1.24136120947017e-14!GO:0051186;cofactor metabolic process;1.63343543815683e-14!GO:0042775;organelle ATP synthesis coupled electron transport;2.39152398944441e-14!GO:0042773;ATP synthesis coupled electron transport;2.39152398944441e-14!GO:0006399;tRNA metabolic process;2.8470397243208e-14!GO:0004386;helicase activity;3.18975048984946e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;3.71992245052805e-14!GO:0019941;modification-dependent protein catabolic process;4.23019307438535e-14!GO:0043632;modification-dependent macromolecule catabolic process;4.23019307438535e-14!GO:0030964;NADH dehydrogenase complex (quinone);4.61091479831955e-14!GO:0045271;respiratory chain complex I;4.61091479831955e-14!GO:0005747;mitochondrial respiratory chain complex I;4.61091479831955e-14!GO:0006511;ubiquitin-dependent protein catabolic process;8.34061112793231e-14!GO:0044257;cellular protein catabolic process;9.38532522716372e-14!GO:0003743;translation initiation factor activity;9.96543097190649e-14!GO:0005643;nuclear pore;1.09400407390134e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.47084173393699e-13!GO:0043687;post-translational protein modification;1.51175840041874e-13!GO:0006413;translational initiation;2.83703130760041e-13!GO:0051082;unfolded protein binding;3.96274227490507e-13!GO:0042981;regulation of apoptosis;7.87115225704091e-13!GO:0048770;pigment granule;7.87115225704091e-13!GO:0042470;melanosome;7.87115225704091e-13!GO:0065004;protein-DNA complex assembly;9.45184693234615e-13!GO:0006364;rRNA processing;1.03603005629037e-12!GO:0050657;nucleic acid transport;1.2514955312487e-12!GO:0051236;establishment of RNA localization;1.2514955312487e-12!GO:0050658;RNA transport;1.2514955312487e-12!GO:0043067;regulation of programmed cell death;1.30833210621116e-12!GO:0016568;chromatin modification;1.49489236210784e-12!GO:0006403;RNA localization;1.83759015738452e-12!GO:0008026;ATP-dependent helicase activity;2.31267152944588e-12!GO:0016072;rRNA metabolic process;2.45034447008755e-12!GO:0006366;transcription from RNA polymerase II promoter;7.03586411951755e-12!GO:0016607;nuclear speck;8.45768801871934e-12!GO:0006446;regulation of translational initiation;8.45768801871934e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;9.76534086812765e-12!GO:0006732;coenzyme metabolic process;1.46797718207159e-11!GO:0046930;pore complex;1.73723841626761e-11!GO:0003712;transcription cofactor activity;1.89721722646009e-11!GO:0065002;intracellular protein transport across a membrane;1.99479058095539e-11!GO:0044432;endoplasmic reticulum part;4.05627885186809e-11!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;4.5361410954666e-11!GO:0004812;aminoacyl-tRNA ligase activity;4.5361410954666e-11!GO:0016875;ligase activity, forming carbon-oxygen bonds;4.5361410954666e-11!GO:0009055;electron carrier activity;4.84231561919367e-11!GO:0051028;mRNA transport;8.58398596231081e-11!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.02273206367334e-10!GO:0030163;protein catabolic process;1.30515760937357e-10!GO:0043038;amino acid activation;1.38678899150452e-10!GO:0006418;tRNA aminoacylation for protein translation;1.38678899150452e-10!GO:0043039;tRNA aminoacylation;1.38678899150452e-10!GO:0017038;protein import;1.548965877868e-10!GO:0048193;Golgi vesicle transport;2.04528370740834e-10!GO:0005783;endoplasmic reticulum;2.26764997379252e-10!GO:0009259;ribonucleotide metabolic process;2.54567600314287e-10!GO:0006261;DNA-dependent DNA replication;2.62101735038938e-10!GO:0043566;structure-specific DNA binding;2.93275253478751e-10!GO:0008639;small protein conjugating enzyme activity;4.33337863990461e-10!GO:0031497;chromatin assembly;4.3358789654881e-10!GO:0006164;purine nucleotide biosynthetic process;5.07722339005056e-10!GO:0006163;purine nucleotide metabolic process;5.21543778947536e-10!GO:0006916;anti-apoptosis;5.24103520081564e-10!GO:0006793;phosphorus metabolic process;5.94725561565344e-10!GO:0006796;phosphate metabolic process;5.94725561565344e-10!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;8.18343156610415e-10!GO:0004842;ubiquitin-protein ligase activity;9.58517259441566e-10!GO:0003697;single-stranded DNA binding;9.65626153617535e-10!GO:0051246;regulation of protein metabolic process;1.08083847116462e-09!GO:0009260;ribonucleotide biosynthetic process;1.20428234284203e-09!GO:0006334;nucleosome assembly;1.24807471670264e-09!GO:0016192;vesicle-mediated transport;1.30487847833021e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.7715399367942e-09!GO:0019787;small conjugating protein ligase activity;1.9781610881115e-09!GO:0030532;small nuclear ribonucleoprotein complex;2.0169745290013e-09!GO:0043069;negative regulation of programmed cell death;2.55457145782474e-09!GO:0043066;negative regulation of apoptosis;3.10747050307108e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;4.80674276959842e-09!GO:0000775;chromosome, pericentric region;6.45267871971547e-09!GO:0009150;purine ribonucleotide metabolic process;6.45267871971547e-09!GO:0009152;purine ribonucleotide biosynthetic process;6.48513988347382e-09!GO:0007005;mitochondrion organization and biogenesis;6.66311241835934e-09!GO:0051188;cofactor biosynthetic process;6.88843894754735e-09!GO:0008565;protein transporter activity;6.88843894754735e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;6.962772277058e-09!GO:0015078;hydrogen ion transmembrane transporter activity;8.58728321526071e-09!GO:0009056;catabolic process;9.57490791704378e-09!GO:0015630;microtubule cytoskeleton;1.05573237998364e-08!GO:0019829;cation-transporting ATPase activity;1.32678117129892e-08!GO:0042175;nuclear envelope-endoplasmic reticulum network;2.87793315406495e-08!GO:0016787;hydrolase activity;3.50779239795594e-08!GO:0016881;acid-amino acid ligase activity;3.75961441379739e-08!GO:0016310;phosphorylation;3.80876019448457e-08!GO:0005789;endoplasmic reticulum membrane;3.80876019448457e-08!GO:0009060;aerobic respiration;3.9482684952982e-08!GO:0050794;regulation of cellular process;5.0782093967746e-08!GO:0009142;nucleoside triphosphate biosynthetic process;5.47261754224085e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;5.47261754224085e-08!GO:0005839;proteasome core complex (sensu Eukaryota);5.61364322246919e-08!GO:0051170;nuclear import;5.90428767467559e-08!GO:0015986;ATP synthesis coupled proton transport;6.91100614776344e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;6.91100614776344e-08!GO:0016740;transferase activity;7.16980003563468e-08!GO:0032446;protein modification by small protein conjugation;8.61162675382907e-08!GO:0016779;nucleotidyltransferase activity;9.35062773689596e-08!GO:0005819;spindle;9.75972675710922e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.14481265226657e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.14481265226657e-07!GO:0009199;ribonucleoside triphosphate metabolic process;1.43336719990585e-07!GO:0009141;nucleoside triphosphate metabolic process;1.49160373474389e-07!GO:0016469;proton-transporting two-sector ATPase complex;1.57663799599318e-07!GO:0016567;protein ubiquitination;1.69697049944907e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.95240115530054e-07!GO:0006606;protein import into nucleus;2.23588200463879e-07!GO:0045333;cellular respiration;2.58959383520493e-07!GO:0000075;cell cycle checkpoint;2.64698788016293e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.85413428907565e-07!GO:0009144;purine nucleoside triphosphate metabolic process;2.85413428907565e-07!GO:0004298;threonine endopeptidase activity;3.14213340679769e-07!GO:0030120;vesicle coat;3.32904395056566e-07!GO:0030662;coated vesicle membrane;3.32904395056566e-07!GO:0005794;Golgi apparatus;3.34646290541874e-07!GO:0005667;transcription factor complex;3.62956437844116e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;4.94052961168673e-07!GO:0008094;DNA-dependent ATPase activity;5.25162446360721e-07!GO:0006310;DNA recombination;5.33785944590506e-07!GO:0016563;transcription activator activity;5.69896487179463e-07!GO:0006754;ATP biosynthetic process;5.92421967113469e-07!GO:0006753;nucleoside phosphate metabolic process;5.92421967113469e-07!GO:0006099;tricarboxylic acid cycle;5.92421967113469e-07!GO:0046356;acetyl-CoA catabolic process;5.92421967113469e-07!GO:0048523;negative regulation of cellular process;5.97712640390185e-07!GO:0051325;interphase;6.41263343976044e-07!GO:0009108;coenzyme biosynthetic process;6.43794389325309e-07!GO:0005657;replication fork;6.74997959201233e-07!GO:0000245;spliceosome assembly;7.37685773999828e-07!GO:0045259;proton-transporting ATP synthase complex;7.62721298724151e-07!GO:0015077;monovalent inorganic cation transmembrane transporter activity;8.00248386145479e-07!GO:0006084;acetyl-CoA metabolic process;8.00248386145479e-07!GO:0006461;protein complex assembly;9.63044002150718e-07!GO:0003713;transcription coactivator activity;1.17722751288157e-06!GO:0006888;ER to Golgi vesicle-mediated transport;1.27583182293119e-06!GO:0019899;enzyme binding;1.47103807505671e-06!GO:0009117;nucleotide metabolic process;1.49621589554714e-06!GO:0046034;ATP metabolic process;1.96310446663685e-06!GO:0045786;negative regulation of progression through cell cycle;2.16850113887709e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;2.48313983114135e-06!GO:0031324;negative regulation of cellular metabolic process;2.53403658841178e-06!GO:0003899;DNA-directed RNA polymerase activity;2.54573604752012e-06!GO:0007051;spindle organization and biogenesis;2.62086094067503e-06!GO:0005762;mitochondrial large ribosomal subunit;2.75386441550291e-06!GO:0000315;organellar large ribosomal subunit;2.75386441550291e-06!GO:0005768;endosome;3.03535665099499e-06!GO:0006752;group transfer coenzyme metabolic process;3.48435298805577e-06!GO:0048475;coated membrane;3.52359304389326e-06!GO:0030117;membrane coat;3.52359304389326e-06!GO:0005813;centrosome;4.22614076179017e-06!GO:0051168;nuclear export;4.30347928199316e-06!GO:0051187;cofactor catabolic process;5.17469220986443e-06!GO:0048519;negative regulation of biological process;5.30602592276617e-06!GO:0003690;double-stranded DNA binding;5.90826544988546e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;5.95567495250189e-06!GO:0051329;interphase of mitotic cell cycle;5.96640862312207e-06!GO:0003724;RNA helicase activity;6.62180229648601e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;6.74067227158373e-06!GO:0000786;nucleosome;6.98526236909917e-06!GO:0009109;coenzyme catabolic process;6.98526236909917e-06!GO:0005793;ER-Golgi intermediate compartment;7.17641037621302e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;7.64896243300822e-06!GO:0015399;primary active transmembrane transporter activity;7.64896243300822e-06!GO:0005815;microtubule organizing center;8.5911177862254e-06!GO:0003684;damaged DNA binding;9.59106496592022e-06!GO:0006417;regulation of translation;1.00677308539266e-05!GO:0000151;ubiquitin ligase complex;1.04605330612408e-05!GO:0019222;regulation of metabolic process;1.07436300530997e-05!GO:0005525;GTP binding;1.36844123291865e-05!GO:0043065;positive regulation of apoptosis;1.39041117494701e-05!GO:0006613;cotranslational protein targeting to membrane;1.47207320549814e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.51421469751642e-05!GO:0043068;positive regulation of programmed cell death;1.886116054972e-05!GO:0050789;regulation of biological process;2.1838326004917e-05!GO:0006917;induction of apoptosis;2.22780443055733e-05!GO:0016564;transcription repressor activity;2.23269171259903e-05!GO:0006302;double-strand break repair;2.28240472144834e-05!GO:0016741;transferase activity, transferring one-carbon groups;2.35674769220336e-05!GO:0008033;tRNA processing;2.6400459156437e-05!GO:0006401;RNA catabolic process;2.70078949491771e-05!GO:0000314;organellar small ribosomal subunit;3.12714392930793e-05!GO:0005763;mitochondrial small ribosomal subunit;3.12714392930793e-05!GO:0008168;methyltransferase activity;3.21602018715321e-05!GO:0012502;induction of programmed cell death;3.34208278706765e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;3.36775143367408e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;3.53132911188338e-05!GO:0005798;Golgi-associated vesicle;3.76780107272729e-05!GO:0006402;mRNA catabolic process;3.76780107272729e-05!GO:0016363;nuclear matrix;3.9630600265983e-05!GO:0006414;translational elongation;4.01631016163282e-05!GO:0048522;positive regulation of cellular process;4.20127779148423e-05!GO:0000776;kinetochore;4.6525980992485e-05!GO:0043623;cellular protein complex assembly;4.75706752389744e-05!GO:0008632;apoptotic program;4.7875913716694e-05!GO:0065009;regulation of a molecular function;5.17444438379536e-05!GO:0007088;regulation of mitosis;5.19186582475578e-05!GO:0007006;mitochondrial membrane organization and biogenesis;5.20712954835991e-05!GO:0003678;DNA helicase activity;5.20712954835991e-05!GO:0007243;protein kinase cascade;5.20712954835991e-05!GO:0003682;chromatin binding;5.286861006454e-05!GO:0009892;negative regulation of metabolic process;5.52071282196026e-05!GO:0003729;mRNA binding;5.58681712469814e-05!GO:0003924;GTPase activity;5.60220089046399e-05!GO:0044452;nucleolar part;5.72969475501869e-05!GO:0005770;late endosome;6.632306721216e-05!GO:0043021;ribonucleoprotein binding;6.99900881609172e-05!GO:0043492;ATPase activity, coupled to movement of substances;7.7648183414635e-05!GO:0007059;chromosome segregation;7.79223820709895e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;8.13836584283663e-05!GO:0005773;vacuole;9.52070179499049e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;9.57584684793295e-05!GO:0031326;regulation of cellular biosynthetic process;9.60860102720571e-05!GO:0006839;mitochondrial transport;0.000101557921964098!GO:0042802;identical protein binding;0.000104145749141332!GO:0016853;isomerase activity;0.000105251370611929!GO:0051427;hormone receptor binding;0.000110818851421875!GO:0000323;lytic vacuole;0.000111035892142526!GO:0005764;lysosome;0.000111035892142526!GO:0048468;cell development;0.000123783098639306!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000126479607552323!GO:0032561;guanyl ribonucleotide binding;0.000147099287031798!GO:0019001;guanyl nucleotide binding;0.000147099287031798!GO:0016481;negative regulation of transcription;0.000160721485685817!GO:0005788;endoplasmic reticulum lumen;0.000196401503893508!GO:0006520;amino acid metabolic process;0.000204490977798351!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000204490977798351!GO:0006383;transcription from RNA polymerase III promoter;0.000209769868191686!GO:0043681;protein import into mitochondrion;0.000210731567766249!GO:0031072;heat shock protein binding;0.000220219400980481!GO:0004527;exonuclease activity;0.000222419372756221!GO:0035257;nuclear hormone receptor binding;0.000222419372756221!GO:0008186;RNA-dependent ATPase activity;0.000228617782555915!GO:0004674;protein serine/threonine kinase activity;0.000230152421232259!GO:0009165;nucleotide biosynthetic process;0.000237584035336062!GO:0007093;mitotic cell cycle checkpoint;0.000246709246327887!GO:0030658;transport vesicle membrane;0.000266092778558498!GO:0016491;oxidoreductase activity;0.000274983101639374!GO:0003714;transcription corepressor activity;0.000282140281659324!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.0002841456268023!GO:0008654;phospholipid biosynthetic process;0.000290677241158518!GO:0005885;Arp2/3 protein complex;0.000291585342337392!GO:0006091;generation of precursor metabolites and energy;0.000302865371182057!GO:0005048;signal sequence binding;0.000307613239107496!GO:0051252;regulation of RNA metabolic process;0.000326562973482019!GO:0031323;regulation of cellular metabolic process;0.000326838218674673!GO:0009889;regulation of biosynthetic process;0.000382778766522555!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000385301613551884!GO:0051052;regulation of DNA metabolic process;0.000386200172153405!GO:0006352;transcription initiation;0.000439263569866505!GO:0045454;cell redox homeostasis;0.000448662151797792!GO:0030880;RNA polymerase complex;0.000455763223323868!GO:0005874;microtubule;0.000456313942385255!GO:0006612;protein targeting to membrane;0.000481813773116663!GO:0032259;methylation;0.000486843428663958!GO:0000228;nuclear chromosome;0.000491647292695284!GO:0006626;protein targeting to mitochondrion;0.00054589781968342!GO:0007017;microtubule-based process;0.000554105649081694!GO:0032508;DNA duplex unwinding;0.000569047223211215!GO:0032392;DNA geometric change;0.000569047223211215!GO:0019752;carboxylic acid metabolic process;0.000572550721289343!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000574784234385532!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000581209803341728!GO:0006082;organic acid metabolic process;0.000596961111883974!GO:0045941;positive regulation of transcription;0.000596961111883974!GO:0015992;proton transport;0.000599010628487129!GO:0006818;hydrogen transport;0.000600163901259905!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000610686184246938!GO:0008022;protein C-terminus binding;0.000618562278746967!GO:0030660;Golgi-associated vesicle membrane;0.000623871588440167!GO:0043414;biopolymer methylation;0.000643111247006207!GO:0004004;ATP-dependent RNA helicase activity;0.000651160164245203!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000664825117237623!GO:0022411;cellular component disassembly;0.000679013331524654!GO:0005684;U2-dependent spliceosome;0.000679013331524654!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.0007403606799067!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.0007403606799067!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.0007403606799067!GO:0016251;general RNA polymerase II transcription factor activity;0.000771492715689722!GO:0006338;chromatin remodeling;0.000800665363454871!GO:0006950;response to stress;0.00080152657623794!GO:0044431;Golgi apparatus part;0.000805645764051466!GO:0004518;nuclease activity;0.000813146408698728!GO:0030384;phosphoinositide metabolic process;0.000875003818571198!GO:0005637;nuclear inner membrane;0.000898966996235446!GO:0042770;DNA damage response, signal transduction;0.000956975292636145!GO:0006650;glycerophospholipid metabolic process;0.000962601857543432!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000962601857543432!GO:0000428;DNA-directed RNA polymerase complex;0.000962601857543432!GO:0031988;membrane-bound vesicle;0.000963796301006444!GO:0000059;protein import into nucleus, docking;0.00106099494250818!GO:0046966;thyroid hormone receptor binding;0.00112109296574228!GO:0006405;RNA export from nucleus;0.00112396737275439!GO:0046489;phosphoinositide biosynthetic process;0.0011549297472018!GO:0000049;tRNA binding;0.00118474209383841!GO:0051920;peroxiredoxin activity;0.00121634703226472!GO:0000792;heterochromatin;0.00123882799036718!GO:0019843;rRNA binding;0.00124964427068681!GO:0048500;signal recognition particle;0.00128986499229768!GO:0006268;DNA unwinding during replication;0.00130536421295033!GO:0044440;endosomal part;0.00132891983601696!GO:0010008;endosome membrane;0.00132891983601696!GO:0043488;regulation of mRNA stability;0.00133074834041602!GO:0043487;regulation of RNA stability;0.00133074834041602!GO:0022890;inorganic cation transmembrane transporter activity;0.00135939205314679!GO:0006350;transcription;0.00140632662239217!GO:0006891;intra-Golgi vesicle-mediated transport;0.00143248079211408!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0015678592271341!GO:0045045;secretory pathway;0.0016223074729088!GO:0031124;mRNA 3'-end processing;0.00163060204149954!GO:0019867;outer membrane;0.00166206125093626!GO:0006284;base-excision repair;0.0017346572706196!GO:0006289;nucleotide-excision repair;0.00176380427208889!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00176511562029062!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00176511562029062!GO:0015631;tubulin binding;0.00186817780492818!GO:0046483;heterocycle metabolic process;0.00192909551027791!GO:0008139;nuclear localization sequence binding;0.00193974579668089!GO:0008312;7S RNA binding;0.00199258613758549!GO:0031968;organelle outer membrane;0.00199339039569234!GO:0006611;protein export from nucleus;0.00212666289242506!GO:0005741;mitochondrial outer membrane;0.00219146211522365!GO:0003702;RNA polymerase II transcription factor activity;0.00221083912298277!GO:0045893;positive regulation of transcription, DNA-dependent;0.00221083912298277!GO:0000287;magnesium ion binding;0.00227850197297661!GO:0007052;mitotic spindle organization and biogenesis;0.0023441136246192!GO:0006595;polyamine metabolic process;0.00237121851513606!GO:0046822;regulation of nucleocytoplasmic transport;0.00237121851513606!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00239522625359805!GO:0003746;translation elongation factor activity;0.00241278946240928!GO:0016023;cytoplasmic membrane-bound vesicle;0.00241278946240928!GO:0032940;secretion by cell;0.00252920236263251!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0025856393217758!GO:0006519;amino acid and derivative metabolic process;0.00263779820258222!GO:0032200;telomere organization and biogenesis;0.0027767378535227!GO:0000723;telomere maintenance;0.0027767378535227!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00295122123095207!GO:0045047;protein targeting to ER;0.00295122123095207!GO:0000922;spindle pole;0.00309305568136114!GO:0003711;transcription elongation regulator activity;0.0031618489022391!GO:0051789;response to protein stimulus;0.00330030435561513!GO:0006986;response to unfolded protein;0.00330030435561513!GO:0048471;perinuclear region of cytoplasm;0.00334331471877458!GO:0046474;glycerophospholipid biosynthetic process;0.0034273416633695!GO:0015980;energy derivation by oxidation of organic compounds;0.00346120613683498!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00349080356144267!GO:0051235;maintenance of localization;0.00349080356144267!GO:0043284;biopolymer biosynthetic process;0.00349080356144267!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00356566489813682!GO:0031982;vesicle;0.0036055239990502!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0036055239990502!GO:0015002;heme-copper terminal oxidase activity;0.0036055239990502!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0036055239990502!GO:0004129;cytochrome-c oxidase activity;0.0036055239990502!GO:0040029;regulation of gene expression, epigenetic;0.0036055239990502!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.0036453524649839!GO:0016859;cis-trans isomerase activity;0.00367433472996599!GO:0051656;establishment of organelle localization;0.0036770480693131!GO:0010468;regulation of gene expression;0.00371052216580083!GO:0005876;spindle microtubule;0.0037541463340041!GO:0019318;hexose metabolic process;0.00381327682138406!GO:0005758;mitochondrial intermembrane space;0.00387196626459512!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00395118656180436!GO:0048518;positive regulation of biological process;0.00395968466698036!GO:0009451;RNA modification;0.00398198191016156!GO:0007264;small GTPase mediated signal transduction;0.00399322627568039!GO:0050790;regulation of catalytic activity;0.00408653211496359!GO:0030867;rough endoplasmic reticulum membrane;0.00415448423086162!GO:0008637;apoptotic mitochondrial changes;0.00427599368294094!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00430030091156459!GO:0051539;4 iron, 4 sulfur cluster binding;0.00432189717391173!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00432543256875105!GO:0005996;monosaccharide metabolic process;0.0043642485051678!GO:0006007;glucose catabolic process;0.00446747978693931!GO:0043596;nuclear replication fork;0.00468469169424786!GO:0016272;prefoldin complex;0.00478100570410895!GO:0030663;COPI coated vesicle membrane;0.00482819431479506!GO:0030126;COPI vesicle coat;0.00482819431479506!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00499855716831357!GO:0016126;sterol biosynthetic process;0.00501433459214901!GO:0006144;purine base metabolic process;0.00505554857995979!GO:0006695;cholesterol biosynthetic process;0.00509873701908267!GO:0031252;leading edge;0.00513913035932811!GO:0006270;DNA replication initiation;0.00517052656641671!GO:0031123;RNA 3'-end processing;0.00519379138891211!GO:0004003;ATP-dependent DNA helicase activity;0.00530409523779753!GO:0004576;oligosaccharyl transferase activity;0.00546007421262034!GO:0000209;protein polyubiquitination;0.00560122387171181!GO:0000082;G1/S transition of mitotic cell cycle;0.0057173329469819!GO:0065007;biological regulation;0.00579435819794607!GO:0007010;cytoskeleton organization and biogenesis;0.00582155042078337!GO:0000339;RNA cap binding;0.00614754501522379!GO:0000096;sulfur amino acid metabolic process;0.00626139765086508!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00638648969593012!GO:0016197;endosome transport;0.00639074838159619!GO:0000139;Golgi membrane;0.00644543490947607!GO:0008250;oligosaccharyl transferase complex;0.00661709341705291!GO:0005669;transcription factor TFIID complex;0.00674058247637456!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00688779303805356!GO:0006506;GPI anchor biosynthetic process;0.00720631024822763!GO:0004532;exoribonuclease activity;0.00726603901700463!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00726603901700463!GO:0008276;protein methyltransferase activity;0.00727153879865912!GO:0051540;metal cluster binding;0.00745883712158925!GO:0051536;iron-sulfur cluster binding;0.00745883712158925!GO:0016311;dephosphorylation;0.00748428543760022!GO:0050662;coenzyme binding;0.00756810590709195!GO:0030133;transport vesicle;0.00756810590709195!GO:0048487;beta-tubulin binding;0.00772634923197697!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00773499577727814!GO:0016301;kinase activity;0.00789043676199833!GO:0047485;protein N-terminus binding;0.00806737085288583!GO:0009893;positive regulation of metabolic process;0.00810870138361852!GO:0031970;organelle envelope lumen;0.0083268754931436!GO:0004722;protein serine/threonine phosphatase activity;0.0083268754931436!GO:0044450;microtubule organizing center part;0.0083268754931436!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00836046256179337!GO:0031410;cytoplasmic vesicle;0.00859930909675179!GO:0043022;ribosome binding;0.00864259517151208!GO:0051223;regulation of protein transport;0.0088093556107926!GO:0051087;chaperone binding;0.0088093556107926!GO:0016407;acetyltransferase activity;0.00884105831437986!GO:0051098;regulation of binding;0.00912811944065308!GO:0006505;GPI anchor metabolic process;0.00912811944065308!GO:0031902;late endosome membrane;0.00920105513738362!GO:0031570;DNA integrity checkpoint;0.00936577330368304!GO:0008408;3'-5' exonuclease activity;0.00941868742139536!GO:0030137;COPI-coated vesicle;0.00943456556492964!GO:0016584;nucleosome positioning;0.00945728101955302!GO:0006378;mRNA polyadenylation;0.00948518578237129!GO:0005832;chaperonin-containing T-complex;0.00969832475586816!GO:0045185;maintenance of protein localization;0.00973751301934166!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00978646279221392!GO:0006275;regulation of DNA replication;0.00978646279221392!GO:0008629;induction of apoptosis by intracellular signals;0.00985378984382733!GO:0006308;DNA catabolic process;0.00985378984382733!GO:0006778;porphyrin metabolic process;0.00994961293318201!GO:0033013;tetrapyrrole metabolic process;0.00994961293318201!GO:0009303;rRNA transcription;0.0100065966806188!GO:0000781;chromosome, telomeric region;0.0100859665410589!GO:0008213;protein amino acid alkylation;0.0100859665410589!GO:0006479;protein amino acid methylation;0.0100859665410589!GO:0030125;clathrin vesicle coat;0.0102348307371162!GO:0030665;clathrin coated vesicle membrane;0.0102348307371162!GO:0032984;macromolecular complex disassembly;0.0102628103688465!GO:0030118;clathrin coat;0.0103425492758023!GO:0030262;apoptotic nuclear changes;0.0103438397384799!GO:0009112;nucleobase metabolic process;0.0104254617526955!GO:0009124;nucleoside monophosphate biosynthetic process;0.0105670295599631!GO:0009123;nucleoside monophosphate metabolic process;0.0105670295599631!GO:0005769;early endosome;0.0105670295599631!GO:0000178;exosome (RNase complex);0.0106073807766664!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0107405222697504!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0117335348562286!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0117335348562286!GO:0030127;COPII vesicle coat;0.0117335348562286!GO:0012507;ER to Golgi transport vesicle membrane;0.0117335348562286!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0118591279489736!GO:0033116;ER-Golgi intermediate compartment membrane;0.0119686383696646!GO:0044438;microbody part;0.0121927764473365!GO:0044439;peroxisomal part;0.0121927764473365!GO:0043433;negative regulation of transcription factor activity;0.0125380918384971!GO:0016791;phosphoric monoester hydrolase activity;0.0125692118778305!GO:0016569;covalent chromatin modification;0.0126175015949746!GO:0006497;protein amino acid lipidation;0.0128628786339608!GO:0022406;membrane docking;0.0129066539475103!GO:0048278;vesicle docking;0.0129066539475103!GO:0042393;histone binding;0.0129469356394198!GO:0044262;cellular carbohydrate metabolic process;0.0131672103269659!GO:0046365;monosaccharide catabolic process;0.0136807643342399!GO:0007242;intracellular signaling cascade;0.0137508760776246!GO:0006740;NADPH regeneration;0.0137508760776246!GO:0006098;pentose-phosphate shunt;0.0137508760776246!GO:0044454;nuclear chromosome part;0.013804678355982!GO:0006730;one-carbon compound metabolic process;0.0138131655080716!GO:0003887;DNA-directed DNA polymerase activity;0.0138771657174365!GO:0008287;protein serine/threonine phosphatase complex;0.0140165926427226!GO:0000726;non-recombinational repair;0.0140401256681296!GO:0030217;T cell differentiation;0.0141718999183375!GO:0000819;sister chromatid segregation;0.01420180883224!GO:0043241;protein complex disassembly;0.0142044447749957!GO:0007050;cell cycle arrest;0.0146364234709555!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0146662789270338!GO:0031647;regulation of protein stability;0.0150607190266052!GO:0004721;phosphoprotein phosphatase activity;0.0151046867891397!GO:0022415;viral reproductive process;0.0152799983889559!GO:0030134;ER to Golgi transport vesicle;0.0154865505155642!GO:0000070;mitotic sister chromatid segregation;0.0155651365398987!GO:0018196;peptidyl-asparagine modification;0.0155940480973933!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0155940480973933!GO:0030140;trans-Golgi network transport vesicle;0.0157623240227609!GO:0051053;negative regulation of DNA metabolic process;0.0158305494382231!GO:0018193;peptidyl-amino acid modification;0.0162565354685775!GO:0031325;positive regulation of cellular metabolic process;0.0164224158992735!GO:0006904;vesicle docking during exocytosis;0.0165235980437603!GO:0031625;ubiquitin protein ligase binding;0.0167318135220914!GO:0032507;maintenance of cellular protein localization;0.0168567545663797!GO:0031903;microbody membrane;0.0170059006475031!GO:0005778;peroxisomal membrane;0.0170059006475031!GO:0008180;signalosome;0.0170798702818493!GO:0006779;porphyrin biosynthetic process;0.0170867301400417!GO:0033014;tetrapyrrole biosynthetic process;0.0170867301400417!GO:0005869;dynactin complex;0.0173557508496621!GO:0006220;pyrimidine nucleotide metabolic process;0.0174312373305281!GO:0045892;negative regulation of transcription, DNA-dependent;0.0176284161572577!GO:0004860;protein kinase inhibitor activity;0.0183066424249021!GO:0006096;glycolysis;0.0188798799300693!GO:0046983;protein dimerization activity;0.0193343512431787!GO:0000725;recombinational repair;0.0194668997573219!GO:0000724;double-strand break repair via homologous recombination;0.0194668997573219!GO:0046426;negative regulation of JAK-STAT cascade;0.0202377814092861!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0205775519268121!GO:0003677;DNA binding;0.021147685266912!GO:0005774;vacuolar membrane;0.0212192595999001!GO:0019079;viral genome replication;0.0215512340511053!GO:0005765;lysosomal membrane;0.021652895371561!GO:0000077;DNA damage checkpoint;0.0222722643094385!GO:0030176;integral to endoplasmic reticulum membrane;0.0223057704795807!GO:0019320;hexose catabolic process;0.0223057704795807!GO:0046164;alcohol catabolic process;0.0224405858777601!GO:0031371;ubiquitin conjugating enzyme complex;0.0224955517316091!GO:0043601;nuclear replisome;0.0226867349987435!GO:0030894;replisome;0.0226867349987435!GO:0009161;ribonucleoside monophosphate metabolic process;0.0232938311127099!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0232938311127099!GO:0016585;chromatin remodeling complex;0.0233100092640764!GO:0030496;midbody;0.0242545500513403!GO:0004523;ribonuclease H activity;0.0242804518312267!GO:0051318;G1 phase;0.0242804518312267!GO:0000152;nuclear ubiquitin ligase complex;0.0245326333631568!GO:0005092;GDP-dissociation inhibitor activity;0.0245326333631568!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0250241638525933!GO:0042168;heme metabolic process;0.0250778969083233!GO:0006470;protein amino acid dephosphorylation;0.0251047990604555!GO:0043624;cellular protein complex disassembly;0.0251463970650783!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0251463970650783!GO:0007265;Ras protein signal transduction;0.0254266833255008!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0254467160528626!GO:0010257;NADH dehydrogenase complex assembly;0.0254467160528626!GO:0033108;mitochondrial respiratory chain complex assembly;0.0254467160528626!GO:0030130;clathrin coat of trans-Golgi network vesicle;0.0254652140056496!GO:0012510;trans-Golgi network transport vesicle membrane;0.0254652140056496!GO:0000118;histone deacetylase complex;0.0259456516492913!GO:0045069;regulation of viral genome replication;0.0265777171352079!GO:0003709;RNA polymerase III transcription factor activity;0.0270156710472482!GO:0007004;telomere maintenance via telomerase;0.0270283986963295!GO:0006376;mRNA splice site selection;0.027219627981249!GO:0000389;nuclear mRNA 3'-splice site recognition;0.027219627981249!GO:0046467;membrane lipid biosynthetic process;0.0272750207988237!GO:0008017;microtubule binding;0.0272793824140634!GO:0019976;interleukin-2 binding;0.0272793824140634!GO:0004911;interleukin-2 receptor activity;0.0272793824140634!GO:0006301;postreplication repair;0.0273313285402419!GO:0050178;phenylpyruvate tautomerase activity;0.0274551412076767!GO:0032774;RNA biosynthetic process;0.0280000058446763!GO:0006400;tRNA modification;0.0280258091694067!GO:0030218;erythrocyte differentiation;0.0280766729308365!GO:0051640;organelle localization;0.0280766729308365!GO:0009081;branched chain family amino acid metabolic process;0.0280766729308365!GO:0019210;kinase inhibitor activity;0.0280766729308365!GO:0042809;vitamin D receptor binding;0.0281007625199133!GO:0051059;NF-kappaB binding;0.0282387873617138!GO:0046979;TAP2 binding;0.0282768305661694!GO:0046977;TAP binding;0.0282768305661694!GO:0046978;TAP1 binding;0.0282768305661694!GO:0000793;condensed chromosome;0.0289848960795561!GO:0008610;lipid biosynthetic process;0.0291874380143105!GO:0030508;thiol-disulfide exchange intermediate activity;0.0292668647882324!GO:0051651;maintenance of cellular localization;0.0299358255534091!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.0303403620999002!GO:0006518;peptide metabolic process;0.0307368068083642!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0307368068083642!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0307368068083642!GO:0009116;nucleoside metabolic process;0.0309021032437396!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0310539240167019!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0310539240167019!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0310539240167019!GO:0006351;transcription, DNA-dependent;0.0313175786453615!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0316491042076875!GO:0030833;regulation of actin filament polymerization;0.0318233559950042!GO:0005652;nuclear lamina;0.0318955333063247!GO:0005663;DNA replication factor C complex;0.0325179771629117!GO:0051287;NAD binding;0.03264478324661!GO:0051101;regulation of DNA binding;0.0327915533958045!GO:0017134;fibroblast growth factor binding;0.032808471389225!GO:0003725;double-stranded RNA binding;0.0336060475080166!GO:0008538;proteasome activator activity;0.0336060475080166!GO:0006596;polyamine biosynthetic process;0.033767574034858!GO:0042158;lipoprotein biosynthetic process;0.0340831422486138!GO:0035267;NuA4 histone acetyltransferase complex;0.0344313481402951!GO:0006672;ceramide metabolic process;0.0349243892718559!GO:0030521;androgen receptor signaling pathway;0.035078955075055!GO:0006807;nitrogen compound metabolic process;0.0356143263454241!GO:0051881;regulation of mitochondrial membrane potential;0.0363941957138871!GO:0030911;TPR domain binding;0.036639786367654!GO:0008624;induction of apoptosis by extracellular signals;0.0368374420862133!GO:0043631;RNA polyadenylation;0.0370884702101352!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.037240424371115!GO:0006509;membrane protein ectodomain proteolysis;0.0374632730388129!GO:0033619;membrane protein proteolysis;0.0374632730388129!GO:0043189;H4/H2A histone acetyltransferase complex;0.0377055382329436!GO:0001836;release of cytochrome c from mitochondria;0.0377225262298704!GO:0016570;histone modification;0.0384159507821622!GO:0030041;actin filament polymerization;0.0384858292396445!GO:0005784;translocon complex;0.0391156070408659!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0391520998376772!GO:0044437;vacuolar part;0.0392395464868631!GO:0000175;3'-5'-exoribonuclease activity;0.0392395464868631!GO:0000097;sulfur amino acid biosynthetic process;0.0392848137680854!GO:0005689;U12-dependent spliceosome;0.0394847850443634!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0396840666993786!GO:0008097;5S rRNA binding;0.0397953954601092!GO:0030132;clathrin coat of coated pit;0.040710674195422!GO:0048037;cofactor binding;0.0409104273502588!GO:0009615;response to virus;0.0425278414871641!GO:0009067;aspartate family amino acid biosynthetic process;0.042859910688998!GO:0000790;nuclear chromatin;0.0428642427035885!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0428725033176797!GO:0006635;fatty acid beta-oxidation;0.0429167283230519!GO:0006118;electron transport;0.0429765273093073!GO:0006783;heme biosynthetic process;0.0429910012313686!GO:0006406;mRNA export from nucleus;0.0429910012313686!GO:0000123;histone acetyltransferase complex;0.0431385555935492!GO:0009308;amine metabolic process;0.0436118273883756!GO:0032039;integrator complex;0.0438914411036843!GO:0007021;tubulin folding;0.0444421033204269!GO:0030433;ER-associated protein catabolic process;0.0445272580713053!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0445272580713053!GO:0007346;regulation of progression through mitotic cell cycle;0.044753627643542!GO:0006607;NLS-bearing substrate import into nucleus;0.0453747811091679!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0458787214666646!GO:0009066;aspartate family amino acid metabolic process;0.0461348111291459!GO:0035035;histone acetyltransferase binding;0.0469343468260451!GO:0000738;DNA catabolic process, exonucleolytic;0.0470267609037361!GO:0046902;regulation of mitochondrial membrane permeability;0.0470825729176746!GO:0031577;spindle checkpoint;0.0471132412498543!GO:0005881;cytoplasmic microtubule;0.0475446278592182!GO:0045746;negative regulation of Notch signaling pathway;0.0479072131266563!GO:0000910;cytokinesis;0.048606984341498!GO:0046519;sphingoid metabolic process;0.0486622074831061!GO:0035258;steroid hormone receptor binding;0.0487077537497429!GO:0006278;RNA-dependent DNA replication;0.0488570666135911!GO:0009083;branched chain family amino acid catabolic process;0.0495735044405267 | |||
|sample_id=10712 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=POU2F1..3:2.65206052336;HOXA9_MEIS1:2.61205330154;PAX4:1.75338308297;NKX6-1,2:1.65836594222;NFKB1_REL_RELA:1.29626498094;AIRE:1.27081918024;ZIC1..3:1.25816448896;IKZF2:1.249827832;FOXP3:1.18984529598;HOX{A6,A7,B6,B7}:1.17644032542;EVI1:1.16754397479;POU3F1..4:1.13115432971;E2F1..5:1.12045278584;YY1:1.0796074849;GCM1,2:1.07361524451;CREB1:1.07044517186;CDX1,2,4:1.05129399052;ZBTB16:1.00552069883;NKX2-1,4:1.00078792386;ELF1,2,4:1.00076761311;NFY{A,B,C}:0.889448638454;RUNX1..3:0.857048902736;CDC5L:0.855102696622;MYOD1:0.809435211327;ATF4:0.799023108703;PBX1:0.760015964669;ATF5_CREB3:0.741470627532;MYB:0.734229964183;ESR1:0.71764743313;FOXP1:0.667846616362;TOPORS:0.633080922464;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.605342653972;SOX{8,9,10}:0.596433177569;GATA6:0.584907939109;HES1:0.584677532626;SPI1:0.578917056681;ELK1,4_GABP{A,B1}:0.562313727061;ONECUT1,2:0.55845962142;NKX3-1:0.546428405393;CRX:0.529454793563;POU1F1:0.523045866677;PAX6:0.518028405229;STAT5{A,B}:0.509508603701;PAX3,7:0.500012120996;HSF1,2:0.487536071033;NKX2-2,8:0.482041685493;BREu{core}:0.467351220657;PITX1..3:0.443103829293;FOX{F1,F2,J1}:0.429883802475;NRF1:0.411846847985;ARID5B:0.401138199595;CUX2:0.397238556968;PAX8:0.392682553477;ZNF148:0.367564800178;ZNF143:0.357861631004;JUN:0.320396810556;VSX1,2:0.307276511142;SOX17:0.28157070334;DMAP1_NCOR{1,2}_SMARC:0.250545792867;PAX2:0.248814492652;TGIF1:0.240087024992;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.221327589805;TEF:0.211051880256;FOXM1:0.190779452832;GFI1:0.158076848339;PRRX1,2:0.157657086794;GLI1..3:0.126323583669;RORA:0.117857880153;FOXN1:0.116221093481;AHR_ARNT_ARNT2:0.0963720464335;GATA4:0.0955863780077;TFDP1:0.0536882881432;HBP1_HMGB_SSRP1_UBTF:0.0332729218859;RFX2..5_RFXANK_RFXAP:0.000974028204434;IRF1,2:0.000703241131487;TP53:9.97770257685e-05;ALX1:-0.0122968520953;TLX2:-0.0191535134042;SPIB:-0.0202913950911;FOSL2:-0.0246316466838;LEF1_TCF7_TCF7L1,2:-0.0263804306421;UFEwm:-0.0534420052453;HNF4A_NR2F1,2:-0.0674380739668;NANOG:-0.0693458344909;NR1H4:-0.0710506393799;ETS1,2:-0.0731974637823;POU5F1:-0.0993718057781;NR5A1,2:-0.128521199819;GFI1B:-0.148810567444;RXRA_VDR{dimer}:-0.196500133869;NKX2-3_NKX2-5:-0.221210971567;SNAI1..3:-0.238436130344;OCT4_SOX2{dimer}:-0.241604744925;HNF1A:-0.264327131235;ZEB1:-0.2669977742;RREB1:-0.280754319512;NFE2:-0.281893903788;ZNF423:-0.294450659655;PAX1,9:-0.306440915515;bHLH_family:-0.310288794344;FOS_FOS{B,L1}_JUN{B,D}:-0.313064557837;ESRRA:-0.313543194756;NANOG{mouse}:-0.339023124541;HOX{A4,D4}:-0.352587991931;LMO2:-0.356469653398;ZFP161:-0.379859632661;HMGA1,2:-0.381211837509;LHX3,4:-0.397737276923;SRF:-0.414860920087;POU6F1:-0.414976217472;HIF1A:-0.458015930384;BACH2:-0.463187218717;TBP:-0.478743859818;MEF2{A,B,C,D}:-0.488985889801;NFE2L1:-0.492037377968;ADNP_IRX_SIX_ZHX:-0.502722715393;NKX3-2:-0.504263712754;DBP:-0.509577569613;FOXL1:-0.533262366213;HLF:-0.53356505463;HOX{A5,B5}:-0.537589478891;FOXD3:-0.55382783873;CEBPA,B_DDIT3:-0.56302233848;MYFfamily:-0.573789654197;MTF1:-0.587118955276;ZNF384:-0.592241103357;PPARG:-0.598768991748;TFAP4:-0.616519689382;HAND1,2:-0.627876248921;SOX2:-0.652522299123;BPTF:-0.661485977884;PDX1:-0.664382056248;SOX5:-0.677275687565;EGR1..3:-0.681075293048;RFX1:-0.712748483759;NR6A1:-0.71439614516;NFIL3:-0.716644108744;XCPE1{core}:-0.71947896226;REST:-0.719716973284;AR:-0.71972830198;ATF6:-0.725792748667;SMAD1..7,9:-0.741836165414;KLF4:-0.750863031728;RBPJ:-0.75225940321;ATF2:-0.793391454672;NFE2L2:-0.799532595836;EP300:-0.811162886883;SREBF1,2:-0.854532412829;MTE{core}:-0.854926642077;FOX{I1,J2}:-0.872201131087;NHLH1,2:-0.879993483745;GTF2A1,2:-0.904107000805;TAL1_TCF{3,4,12}:-0.9062210193;STAT2,4,6:-0.914483188827;HMX1:-0.943228435187;ALX4:-0.946226083342;STAT1,3:-0.962633683615;MYBL2:-0.968827140062;GZF1:-0.986110121672;IRF7:-0.998015007607;T:-1.07087734228;SP1:-1.08606246284;IKZF1:-1.10081771011;XBP1:-1.12586698472;PATZ1:-1.1308208845;EN1,2:-1.13240388209;HIC1:-1.13707650927;NFATC1..3:-1.14237099323;NR3C1:-1.15594817921;FOX{D1,D2}:-1.16612033273;PRDM1:-1.20971883814;FOXQ1:-1.25136788102;EBF1:-1.27644295354;TFCP2:-1.32378582178;MED-1{core}:-1.3243181653;MAFB:-1.33554879636;ZBTB6:-1.3399663007;MZF1:-1.34705600987;RXR{A,B,G}:-1.36327836382;SPZ1:-1.38252631095;FOXO1,3,4:-1.38874919455;TFAP2B:-1.39357395785;TFAP2{A,C}:-1.42365568178;TEAD1:-1.44892655313;NFIX:-1.51853068964;TBX4,5:-1.55781569482;ZNF238:-1.58314760322;TLX1..3_NFIC{dimer}:-1.64289551433;MAZ:-1.71717683067;GTF2I:-1.72368992721;PAX5:-1.75272111494;FOXA2:-1.82057864531 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10712-109I1;search_select_hide=table117:FF:10712-109I1 | |||
}} | }} |
Latest revision as of 15:01, 3 June 2020
Name: | hairy cell leukemia cell line:Mo |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11843 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11843
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11843
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0136 |
10 | 10 | 0.019 |
100 | 100 | 0.214 |
101 | 101 | 0.811 |
102 | 102 | 0.307 |
103 | 103 | 0.48 |
104 | 104 | 0.685 |
105 | 105 | 0.796 |
106 | 106 | 0.88 |
107 | 107 | 0.361 |
108 | 108 | 0.997 |
109 | 109 | 0.0477 |
11 | 11 | 0.0827 |
110 | 110 | 0.16 |
111 | 111 | 0.0344 |
112 | 112 | 0.172 |
113 | 113 | 0.702 |
114 | 114 | 0.11 |
115 | 115 | 0.964 |
116 | 116 | 0.244 |
117 | 117 | 0.0329 |
118 | 118 | 0.172 |
119 | 119 | 0.105 |
12 | 12 | 0.902 |
120 | 120 | 0.834 |
121 | 121 | 0.929 |
122 | 122 | 1 |
123 | 123 | 2.13271e-4 |
124 | 124 | 0.257 |
125 | 125 | 0.298 |
126 | 126 | 0.995 |
127 | 127 | 0.415 |
128 | 128 | 0.736 |
129 | 129 | 0.299 |
13 | 13 | 0.0177 |
130 | 130 | 0.768 |
131 | 131 | 0.812 |
132 | 132 | 0.565 |
133 | 133 | 0.934 |
134 | 134 | 0.702 |
135 | 135 | 0.445 |
136 | 136 | 0.119 |
137 | 137 | 0.638 |
138 | 138 | 0.877 |
139 | 139 | 0.182 |
14 | 14 | 0.915 |
140 | 140 | 0.115 |
141 | 141 | 0.72 |
142 | 142 | 0.771 |
143 | 143 | 0.0711 |
144 | 144 | 0.649 |
145 | 145 | 0.509 |
146 | 146 | 0.793 |
147 | 147 | 0.0842 |
148 | 148 | 0.129 |
149 | 149 | 0.0654 |
15 | 15 | 0.205 |
150 | 150 | 0.904 |
151 | 151 | 0.884 |
152 | 152 | 0.253 |
153 | 153 | 0.945 |
154 | 154 | 0.711 |
155 | 155 | 0.0287 |
156 | 156 | 0.384 |
157 | 157 | 0.97 |
158 | 158 | 0.256 |
159 | 159 | 0.102 |
16 | 16 | 0.744 |
160 | 160 | 0.252 |
161 | 161 | 0.826 |
162 | 162 | 0.921 |
163 | 163 | 0.274 |
164 | 164 | 0.429 |
165 | 165 | 0.488 |
166 | 166 | 0.0493 |
167 | 167 | 0.0483 |
168 | 168 | 0.543 |
169 | 169 | 0.52 |
17 | 17 | 0.544 |
18 | 18 | 0.172 |
19 | 19 | 0.719 |
2 | 2 | 0.323 |
20 | 20 | 0.117 |
21 | 21 | 0.113 |
22 | 22 | 0.867 |
23 | 23 | 0.494 |
24 | 24 | 0.15 |
25 | 25 | 0.0998 |
26 | 26 | 0.141 |
27 | 27 | 0.931 |
28 | 28 | 0.905 |
29 | 29 | 0.0188 |
3 | 3 | 0.141 |
30 | 30 | 0.0796 |
31 | 31 | 0.68 |
32 | 32 | 0.85 |
33 | 33 | 0.555 |
34 | 34 | 0.611 |
35 | 35 | 0.162 |
36 | 36 | 0.0405 |
37 | 37 | 0.321 |
38 | 38 | 0.81 |
39 | 39 | 0.488 |
4 | 4 | 0.204 |
40 | 40 | 0.192 |
41 | 41 | 0.652 |
42 | 42 | 0.171 |
43 | 43 | 0.358 |
44 | 44 | 0.0561 |
45 | 45 | 0.339 |
46 | 46 | 0.13 |
47 | 47 | 0.11 |
48 | 48 | 0.218 |
49 | 49 | 0.122 |
5 | 5 | 0.912 |
50 | 50 | 0.74 |
51 | 51 | 0.494 |
52 | 52 | 0.438 |
53 | 53 | 0.586 |
54 | 54 | 0.81 |
55 | 55 | 0.0539 |
56 | 56 | 0.864 |
57 | 57 | 0.137 |
58 | 58 | 0.0992 |
59 | 59 | 0.778 |
6 | 6 | 0.781 |
60 | 60 | 0.812 |
61 | 61 | 0.149 |
62 | 62 | 0.0698 |
63 | 63 | 0.656 |
64 | 64 | 0.168 |
65 | 65 | 0.945 |
66 | 66 | 0.0437 |
67 | 67 | 0.207 |
68 | 68 | 0.153 |
69 | 69 | 0.565 |
7 | 7 | 0.22 |
70 | 70 | 0.305 |
71 | 71 | 0.0351 |
72 | 72 | 0.82 |
73 | 73 | 0.704 |
74 | 74 | 0.822 |
75 | 75 | 0.0396 |
76 | 76 | 0.487 |
77 | 77 | 0.465 |
78 | 78 | 0.266 |
79 | 79 | 0.869 |
8 | 8 | 0.348 |
80 | 80 | 0.36 |
81 | 81 | 0.0803 |
82 | 82 | 0.467 |
83 | 83 | 0.0478 |
84 | 84 | 0.115 |
85 | 85 | 0.461 |
86 | 86 | 0.388 |
87 | 87 | 0.397 |
88 | 88 | 0.827 |
89 | 89 | 0.987 |
9 | 9 | 0.641 |
90 | 90 | 0.242 |
91 | 91 | 0.532 |
92 | 92 | 0.874 |
93 | 93 | 0.975 |
94 | 94 | 0.229 |
95 | 95 | 0.043 |
96 | 96 | 0.4 |
97 | 97 | 0.0493 |
98 | 98 | 0.288 |
99 | 99 | 0.135 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11843
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101014 Mo-T cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000542 (lymphocyte)
0000219 (motile cell)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0002242 (nucleate cell)
0000255 (eukaryotic cell)
0000084 (T cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0103681 (hairy cell leukemia cell line sample)
0101014 (Mo-T cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000051 (common lymphoid progenitor)