FF:11794-124C3: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005636 | ||
| | |accession_numbers=CAGE;DRX008181;DRR009053;DRZ000478;DRZ001863;DRZ011828;DRZ013213 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003 | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001 | ||
|comment=Changed from previous label. TODO: full classification | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chrX:49121165..49121179,-!p1@FOXP3!2.22!163.10!FOXP3;;chr10:8096631..8096660,+!p1@GATA3!2.03!128.01!GATA3;;chr10:8096772..8096787,+!p2@GATA3!2.01!119.10!GATA3;;chr2:231090433..231090469,+!p1@SP140!1.93!84.45!SP140;;chr7:50343634..50343717,+!p2@IKZF1!1.80!62.06!IKZF1;;chr10:35484053..35484076,+!p1@CREM!1.75!134.58!CREM;;chr14:75988831..75988847,+!p2@BATF!1.69!48.35!BATF;;chr14:75988771..75988826,+!p1@BATF!1.68!61.39!BATF;;chr2:192015701..192015743,-!p1@STAT4!1.66!60.50!STAT4;;chr2:231090471..231090504,+!p2@SP140!1.65!43.34!SP140;;chr3:12330560..12330579,+!p1@PPARG!1.64!48.24!PPARG;;chr2:192015750..192015793,-!p2@STAT4!1.60!52.14!STAT4;;chr17:37934365..37934387,-!p2@IKZF3!1.53!32.53!IKZF3;;chr16:79634624..79634642,-!p1@MAF!1.52!120.99!MAF;;chr6:391743..391759,+!p1@IRF4!1.52!32.31!IRF4;;chr9:117150254..117150271,-!p1@AKNA!1.50!82.44!AKNA;;chr16:79634595..79634620,-!p2@MAF!1.49!53.37!MAF;;chrY:21906594..21906622,-!p1@KDM5D!1.48!28.97!KDM5D;;chr7:50344251..50344288,+!p3@IKZF1!1.46!28.08!IKZF1;;chr20:56195474..56195506,-!p1@ZBP1!1.46!27.52!ZBP1;;chr16:68119324..68119364,+!p1@NFATC3!1.45!117.98!NFATC3;;chr6:106546808..106546833,+!p3@PRDM1!1.45!34.43!PRDM1;;chr10:8095593..8095625,+!p3@GATA3!1.40!28.52!GATA3;;chr7:50348268..50348366,+!p4@IKZF1!1.40!24.18!IKZF1;;chr7:50343895..50343936,+!p5@IKZF1!1.39!23.40!IKZF1;;chr17:37934204..37934241,-!p3@IKZF3!1.39!23.40!IKZF3;;chr7:50344289..50344323,+!p1@IKZF1!1.38!23.06!IKZF1;;chr15:60884706..60884743,-!p1@RORA!1.36!110.52!RORA;;chr1:25256756..25256774,-!p1@RUNX3!1.36!40.78!RUNX3;;chr20:50159198..50159299,-!p1@NFATC2!1.36!31.97!NFATC2;;chr3:18480217..18480239,-!p3@SATB1!1.36!22.17!SATB1;;chr3:18486354..18486377,-!p2@SATB1!1.33!25.62!SATB1;;chr3:63953435..63953499,+!p1@ATXN7!1.30!19.05!ATXN7;;chr1:92951607..92951661,-!p1@GFI1!1.30!18.83!GFI1;;chr13:41593425..41593480,-!p1@ELF1!1.28!111.08!ELF1;;chr19:19779619..19779670,+!p1@ZNF101!1.27!49.02!ZNF101;;chr4:57522674..57522699,-!p5@HOPX!1.25!16.60!HOPX;;chr19:16435625..16435682,+!p1@KLF2!1.24!519.84!KLF2;;chr8:60031619..60031676,-!p1@TOX!1.24!35.32!TOX;;chr19:19729477..19729542,-!p1@PBX4!1.22!33.20!PBX4;;chr17:38020392..38020477,-!p1@IKZF3!1.20!14.93!IKZF3;;chr4:57522598..57522664,-!p3@HOPX!1.19!14.48!HOPX;;chr10:35484090..35484104,+!p6@CREM!1.18!14.26!CREM;;chr17:45810594..45810608,+!p1@TBX21!1.17!13.81!TBX21;;chr4:185395633..185395651,-!p2@IRF2!1.16!21.73!IRF2;;chr20:56195525..56195556,-!p2@ZBP1!1.16!13.48!ZBP1;;chr11:128563948..128564003,+!p1@FLI1!1.13!148.18!FLI1;;chr12:56415246..56415286,+!p2@IKZF4!1.13!12.37!IKZF4;;chr16:88752889..88752921,-!p1@SNAI3!1.11!13.81!SNAI3;;chr7:137620650..137620677,-!p3@CREB3L2!1.11!11.92!CREB3L2;;chr7:77428066..77428132,+!p2@PHTF2!1.10!74.65!PHTF2;;chr19:36204309..36204335,+!p1@ZBTB32!1.10!11.70!ZBTB32;;chr4:57522166..57522260,-!p2@HOPX!1.09!13.15!HOPX;;chr16:79633894..79633954,-!p3@MAF!1.03!19.16!MAF;;chr3:141105705..141105770,+!p4@ZBTB38!1.02!11.48!ZBTB38;;chr19:19779686..19779697,+!p3@ZNF101!1.02!11.03!ZNF101;;chr17:37934280..37934299,-!p6@IKZF3!1.02!9.58!IKZF3;;chr1:158978768..158978800,+!p8@IFI16!1.02!9.47!IFI16;;chr6:106546834..106546850,+!p4@PRDM1!1.01!9.25!PRDM1;;chr1:23857698..23857733,-!p1@E2F2!1.00!16.82!E2F2;;chr6:106546731..106546755,+!p5@PRDM1!1.00!9.02!PRDM1;;chr11:47236584..47236679,+!p1@DDB2!0.99!97.48!DDB2;;chr10:35484804..35484902,+!p2@CREM!0.99!34.65!CREM;;chrY:2803415..2803468,+!p1@ZFY!0.97!8.36!ZFY;;chr16:79634581..79634592,-!p4@MAF!0.97!8.24!MAF;;chr6:45390300..45390335,+!p4@RUNX2!0.96!12.92!RUNX2;;chr10:8097321..8097348,+!p4@GATA3!0.96!8.02!GATA3;;chr12:56415287..56415300,+!p5@IKZF4!0.94!7.69!IKZF4;;chr10:104154246..104154347,+!p3@NFKB2!0.93!48.24!NFKB2;;chr19:4153613..4153652,+!p1@CREB3L3!0.93!7.58!CREB3L3;;chr2:231090344..231090361,-!p3@SP110!0.93!7.46!SP110;;chr17:38020516..38020544,-!p5@IKZF3!0.92!7.35!IKZF3;;chr1:92949331..92949377,-!p2@GFI1!0.92!7.24!GFI1;;chr11:128392085..128392232,-!p1@ETS1!0.91!250.12!ETS1;;chr6:45390269..45390298,+!p5@RUNX2!0.91!12.03!RUNX2;;chr10:8100691..8100732,+!p5@GATA3!0.91!7.13!GATA3;;chr7:137620684..137620711,-!p4@CREB3L2!0.90!7.02!CREB3L2;;chr21:36421147..36421193,-!p10@RUNX1!0.90!7.02!RUNX1;;chr6:106547079..106547114,+!p9@PRDM1!0.90!6.91!PRDM1;;chr1:158979686..158979745,+!p1@IFI16!0.89!235.52!IFI16;;chr20:52226313..52226350,-!p3@ZNF217!0.89!6.80!ZNF217;;chr1:25291475..25291511,-!p2@RUNX3!0.89!6.68!RUNX3;;chr2:242556880..242556899,-!p5@THAP4!0.89!6.68!THAP4;;chr6:15249128..15249177,+!p4@JARID2!0.88!12.26!JARID2;;chr4:57522513..57522548,-!p4@HOPX!0.88!6.57!HOPX;;chr6:106534230..106534254,+!p2@PRDM1!0.87!16.71!PRDM1;;chr6:106546786..106546802,+!p6@PRDM1!0.87!6.46!PRDM1;;chr2:242556900..242556916,-!p6@THAP4!0.87!6.35!THAP4;;chr10:35416142..35416169,+!p3@CREM!0.86!17.38!CREM;;chr4:185395590..185395627,-!p3@IRF2!0.85!7.69!IRF2;;chr16:88752861..88752884,-!p2@SNAI3!0.85!6.13!SNAI3;;chr7:64838786..64838809,+!p2@ZNF92!0.84!35.65!ZNF92;;chr2:238600933..238600985,+!p3@LRRFIP1!0.84!34.31!LRRFIP1;;chr21:36421535..364216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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000084;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000542;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000624;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000789;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000893;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 40: | ||
|fonse_treatment=EFO:0000369,FF:0000409,FF:0011127,FF:11794-124C3 | |fonse_treatment=EFO:0000369,FF:0000409,FF:0011127,FF:11794-124C3 | ||
|fonse_treatment_closure=EFO:0000369,FF:0000409,FF:0011127,FF:11794-124C3 | |fonse_treatment_closure=EFO:0000369,FF:0000409,FF:0011127,FF:11794-124C3 | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD4%252bCD25%252bCD45RA-%2520memory%2520regulatory%2520T%2520cells%2520expanded%252c%2520donor1.CNhs13204.11794-124C3.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD4%252bCD25%252bCD45RA-%2520memory%2520regulatory%2520T%2520cells%2520expanded%252c%2520donor1.CNhs13204.11794-124C3.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD4%252bCD25%252bCD45RA-%2520memory%2520regulatory%2520T%2520cells%2520expanded%252c%2520donor1.CNhs13204.11794-124C3.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD4%252bCD25%252bCD45RA-%2520memory%2520regulatory%2520T%2520cells%2520expanded%252c%2520donor1.CNhs13204.11794-124C3.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD4%252bCD25%252bCD45RA-%2520memory%2520regulatory%2520T%2520cells%2520expanded%252c%2520donor1.CNhs13204.11794-124C3.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11794-124C3 | |||
|is_a=EFO:0002091;;FF:0000002;;FF:0000210 | |is_a=EFO:0002091;;FF:0000002;;FF:0000210 | ||
|is_obsolete= | |||
|library_id=CNhs13204 | |||
|library_id_phase_based=2:CNhs13204 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11794 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11794 | |||
|name=CD4+CD25+CD45RA- memory regulatory T cells expanded, donor1 | |||
|namespace= | |namespace= | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13204,LSID1004,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.141296590884783,0.125231147636021,-0.0006054628946765,-0.157209028884646,0,0,0,0,0,0,0,0,0,0,0.388871007699201,0.0873628578078838,0,-0.0659601525405438,0,0,0,0,0.347430530801241,-0.0979578962680575,0,0,-0.0870821111803524,0,0,0,0,0,0,0,0,0,0,0,0,-0.132453589174818,0,0,0,0,0,0,0,0,0.330512689637598,0,0,0,0.0458744785985099,0,-0.0561158530694396,0,0.028238786393416,0,0,0.0627170781998481,0,0,0,0,0,0,0.0458744785985099,0,0.0458744785985099,0,1.01059961488532,0,0,0.0458744785985099,0,0,0,-0.0109333660607063,0,0,0,0,0,-0.0553715309520668,-0.251138459663112,0,0,0,-0.263229561357652,-0.100039146293567,0.0229372392992549,0,0.194435503849601,0,0.0620253541752387,-0.0947957718969535,0,0,0,0,0,0.0436814289039419,0,0,0,0,0,0,0,0,0,0,0,-0.0163432412159885,0,0,0,-0.0306358713632606,-0.150490368984887,0,0.0458744785985099,0,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0.192303196034017,0.0620253541752387,0,0,0,0,0,0,0,0,0,0,0,-0.247178875285564,0.0436814289039419,-0.197329549453171,0.0165455628894732,0,0.0458744785985099,-0.165430586644482,0,0,0,0.0458744785985099,0,0,0.0458744785985099,0.0458744785985099,0,-0.128119866952565,0,-0.0504125515893149,0,0.222316512804603,0,0,0,-0.00385760992723821,0,-0.130576632245568,-0.0683442610773682,0,0.0608839898886582,0,0,-0.130407642413373,0,0.00435166384228053,-0.0827201683234173,0.0458744785985099,-0.648854437612733,0.00523341447650649,0,0,0,-0.458231119227605,-0.82607571735887,0,0,0.0519354136487465,0.376161404746882,0.0433102052516779,0,-0.391044581551635,0,-0.423471503245136,-0.0604397418968705,0,-0.113890109879992,0,0,0,0,0,0,0,0,0,0,0,-0.0574934668214365,-0.166927891266024,-0.00522488941835735,0,0,0,0.107636094646066,0,0,-0.0258556251553261,-0.304861534698349,-0.0377465068937377,-0.555550316351279,0,-0.256515248411403,-0.288691389801357,-0.558609471236755,-0.263229561357652,-0.147401849371139,-0.102618861741963,-0.0352916758318587,-0.221294399785848,-0.593969433079994,-0.0693372191066961,0.0866377228085162,0.00139168396528856,-1.18553402968859,-0.0379227521149907,0,0,-0.0775089264793031,0.727348727895714,0,0,-0.0456690357813653,-0.212475115652168,-0.604368768272513,-0.69944122031106,-0.41284988265781,-0.238790503525534,-0.0395325284566706,-0.132309988112446,-0.0419423592171042,-0.398635085604445,-0.186172532257479,0,-0.0877514257027229,-0.0812011224091209,0.0316878224740421,0.632430850742323,-0.00950560793064805,-0.35874631417496,0.0917164443355769,0,-0.696355375114424,-0.103111357996928,0,0,0.0360665165076356,0,0,0.0458744785985099,0,0.0458744785985099,-0.143964059500178,0.60772099974108,0.156015446143656,0,-0.0346077146258187,0,0.272845388751216,0,0.105939973389696,-0.020778749821373,-0.0783512187242199,-0.0166423449315969,0,-0.0385697506305413,-0.252216190252705,-0.119116217740493,-0.200078292587135,0.191942236572766,0.380821466356925,0.123702939645612,-0.220243617521076,0.109096497805264,-0.115692227579312,-0.0422523538767778,-0.051299070243725,-0.456845359497069,0.212375808455944,-0.154709651609437,-0.231866391100171,0,0.137433497363807,0,0.018910234091186,0,0.389613404652394,-0.290044688088648,0.987804061632972,0.0964466536371926,0,-0.174664553226602,-0.788130937773974,0,-0.122420834731843,0,0,-0.150367083334639,-0.697695966512583,0.0247023602300081,-0.138989456679195,0,-0.744205679791147,0,0,-0.169175729548817,0.0149130256202029,0.0458744785985099,-0.266952107318853,-0.0574552937181328,-0.110507289811408,0.0763321225990834,0.125231147636021,0,-0.645700337992725,0,0.0873628578078838,-0.56005358521952,-0.0870340472637463,-0.251138459663112,0.361517405892292,-0.0624425459986825,-0.108622809454255,0,0,0.0992289033336619,1.47176810869291,-0.159973060151553,0,0,0.0144714882554095,0,0,0,0,-0.0568873559083455,0,0.098274207414273,0,0,0,0,0,0.155373952104241,-0.229602182580427,0,-0.202698630646503,0,0,0,0,0,0.0433609024248491,0,0,0.200431456520413,-0.0583282421681402,0.153739253622417,0,0.0229372392992549,0,0,-0.128360544745591,-0.0109333660607063,0.125231147636021,0.0604404895363858,0,0.150807310485584,0,0,0.0012218680186725,0,0,0.0229372392992549,0,0.0296324007542198,-0.0832285426599759,0,0,0,-0.189591543793907,0.0458744785985099,0,0,0,-0.0228622787714923,0,0,-0.409202779340408,0,-0.112449904149629,0.0784788258661037,0,0.142695662753479,0.278052303956483,-1.05923127726387,0,0,-0.261347131789888,0,0,0.104318616574359,0,0,0,0,0,0,0,0,0.388871007699201,0.495140909101109,0,0,0,0,0,0,0,0,0.0458744785985099,0,0,0.115870785454208,0.158165006726081,-0.0107939627133347,0,0,0,0,0,0,-0.0241060230789031,-0.0192157897808556,0.0229372392992549,0,0,0,0,0.0458744785985099,0,0,-0.146299474879094,0,0.0458744785985099,0.0873628578078838,0,0,0.028238786393416,0,0,0,0,-0.314418057769292,0,0,-0.0006054628946765,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0689841099985698,-0.0565463057458986,0,0,0,0,0,0.125231147636021,0,0.00192337109274704,0,0,0,0,1.94163145704529,0,0,0,-0.104796384789156,0,0.141296590884783,0,0,0.0458744785985099,0,0,0.0458744785985099,0.0436814289039419,0.0229372392992549,0,0,0,0,0,0,0,0,0,0.125194531692296,0,0,0,-0.400736948760579,-0.0247755787802223,-0.108198582411442,0,0,0,-0.232628352633041,0,0,0,0,0,0,0.0123410048754148,0,0,0,0,0,0,0,0,0,0,0,0,0,0.718800307844237,0,0,0,0.0458744785985099,0,0,0,0.0873628578078838,0,0,0,0.0130384626121124,0,0,0,0,0,0,0,-0.0979578962680575,0,0,-0.0690955705012712,0,0,0,0,0,0,-0.244295411752768,-0.283220399823148,-0.154759570344306,0,0,0,-0.054385572482455,0.0458744785985099,0,-0.0482120461578062,0,0.0205854703889825,0.125231147636021,0,0,0,0,0,0,0,0,0,0,0,0.769913910149024,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0659601525405438,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0666186682031969,0,0,0,0,0,0,0.0873628578078838,0.0458744785985099,0,0.0229372392992549,0,0,0,0,0,0,0.028604210542594,0.0458744785985099,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.160060705412945,-0.0800184682686384,0,0,0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| |||
|rna_box=124 | |||
|rna_catalog_number= | |||
|rna_concentration=0.26264 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=17 | |||
|rna_od260/230=1.8 | |||
|rna_od260/280=2.02 | |||
|rna_position=C3 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=124C3 | |||
|rna_weight_ug=2.6264 | |||
|sample_age=25 | |||
|sample_category=primary cells | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=T cell | |||
|sample_collaboration=Michael Rehli (University of Regensberg) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;5.58748383437507e-232!GO:0043227;membrane-bound organelle;3.31451761985055e-198!GO:0043231;intracellular membrane-bound organelle;9.87706779992597e-198!GO:0043226;organelle;4.95878891747521e-187!GO:0043229;intracellular organelle;2.70597874274279e-186!GO:0005737;cytoplasm;2.20634006823222e-153!GO:0044422;organelle part;4.19484073816594e-131!GO:0044446;intracellular organelle part;2.8905834715858e-129!GO:0044444;cytoplasmic part;2.96494647431402e-107!GO:0032991;macromolecular complex;5.79313169337576e-103!GO:0005634;nucleus;3.60848956253125e-97!GO:0044237;cellular metabolic process;2.75195490289887e-95!GO:0043170;macromolecule metabolic process;1.18875854855379e-94!GO:0044238;primary metabolic process;7.28069427771162e-92!GO:0030529;ribonucleoprotein complex;2.40932165977296e-85!GO:0003723;RNA binding;4.83136929686428e-77!GO:0044428;nuclear part;1.41693241566297e-76!GO:0043233;organelle lumen;1.13579089240801e-66!GO:0031974;membrane-enclosed lumen;1.13579089240801e-66!GO:0043283;biopolymer metabolic process;1.80794666850531e-62!GO:0005515;protein binding;1.82534136602021e-60!GO:0005739;mitochondrion;2.92793909994443e-57!GO:0006412;translation;1.86187993344062e-55!GO:0043234;protein complex;1.08885959037542e-52!GO:0019538;protein metabolic process;4.04935350060157e-52!GO:0033036;macromolecule localization;7.45847918317659e-51!GO:0006396;RNA processing;8.34776964575465e-50!GO:0010467;gene expression;1.26632885818829e-49!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.514251001137e-49!GO:0015031;protein transport;3.45320285814159e-49!GO:0044267;cellular protein metabolic process;6.30949431963517e-49!GO:0005840;ribosome;2.55121837007389e-48!GO:0044260;cellular macromolecule metabolic process;4.66071011290401e-48!GO:0045184;establishment of protein localization;6.92384575791136e-48!GO:0008104;protein localization;2.12614373659093e-47!GO:0031981;nuclear lumen;1.7186190596291e-45!GO:0016071;mRNA metabolic process;9.75075769315818e-45!GO:0003735;structural constituent of ribosome;5.13245899187325e-43!GO:0009059;macromolecule biosynthetic process;4.25890085645789e-42!GO:0031090;organelle membrane;1.27028361742198e-41!GO:0044429;mitochondrial part;1.1665043274094e-40!GO:0006397;mRNA processing;1.23277508254778e-38!GO:0006259;DNA metabolic process;1.34730160589055e-38!GO:0031967;organelle envelope;1.58642014946682e-38!GO:0008380;RNA splicing;2.866237875254e-38!GO:0031975;envelope;3.6245395599295e-38!GO:0033279;ribosomal subunit;4.19872962157087e-37!GO:0005829;cytosol;8.06480595979705e-36!GO:0046907;intracellular transport;1.4134005850895e-35!GO:0016043;cellular component organization and biogenesis;8.88906753652248e-35!GO:0009058;biosynthetic process;8.91885736253293e-34!GO:0003676;nucleic acid binding;8.91885736253293e-34!GO:0044249;cellular biosynthetic process;1.42232839058333e-33!GO:0006886;intracellular protein transport;3.3546776233787e-33!GO:0065003;macromolecular complex assembly;1.44511263170895e-31!GO:0005654;nucleoplasm;4.07371027712272e-30!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.40548062439186e-29!GO:0005681;spliceosome;6.02904302715871e-29!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.46533483278732e-28!GO:0006996;organelle organization and biogenesis;4.03423710901177e-28!GO:0022607;cellular component assembly;2.20462273301458e-27!GO:0000166;nucleotide binding;3.64796729983993e-27!GO:0051641;cellular localization;6.63005930453675e-27!GO:0051649;establishment of cellular localization;1.31710141197338e-26!GO:0005740;mitochondrial envelope;2.55684975855514e-26!GO:0043228;non-membrane-bound organelle;1.17546645715723e-25!GO:0043232;intracellular non-membrane-bound organelle;1.17546645715723e-25!GO:0007049;cell cycle;3.61749428731896e-25!GO:0044445;cytosolic part;4.23049161862884e-25!GO:0031966;mitochondrial membrane;6.38587895475034e-25!GO:0006915;apoptosis;1.73746996920507e-24!GO:0012501;programmed cell death;1.8347718837617e-24!GO:0019866;organelle inner membrane;2.1569050256005e-24!GO:0008219;cell death;9.95770114184183e-24!GO:0016265;death;9.95770114184183e-24!GO:0016070;RNA metabolic process;1.0093972145e-23!GO:0006512;ubiquitin cycle;1.26906088147452e-23!GO:0044451;nucleoplasm part;6.7437849118277e-23!GO:0006974;response to DNA damage stimulus;8.83601537990258e-23!GO:0005743;mitochondrial inner membrane;5.97715602874856e-22!GO:0006119;oxidative phosphorylation;7.35533206003412e-21!GO:0022618;protein-RNA complex assembly;2.2291150620671e-20!GO:0032553;ribonucleotide binding;2.42510259523747e-20!GO:0032555;purine ribonucleotide binding;2.42510259523747e-20!GO:0005694;chromosome;3.06864906172427e-20!GO:0022402;cell cycle process;3.17030125123368e-20!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;4.71702251232066e-20!GO:0043412;biopolymer modification;5.25586746865316e-20!GO:0016462;pyrophosphatase activity;5.47952805638182e-20!GO:0016817;hydrolase activity, acting on acid anhydrides;5.47952805638182e-20!GO:0017076;purine nucleotide binding;8.95802968513114e-20!GO:0017111;nucleoside-triphosphatase activity;1.12338630463075e-19!GO:0051276;chromosome organization and biogenesis;2.42049955130034e-19!GO:0006281;DNA repair;3.04332513003245e-19!GO:0015935;small ribosomal subunit;4.7722977972444e-19!GO:0015934;large ribosomal subunit;5.79882704646084e-19!GO:0044427;chromosomal part;7.09812349033324e-19!GO:0044265;cellular macromolecule catabolic process;1.30135932624969e-18!GO:0044455;mitochondrial membrane part;2.05282251265432e-18!GO:0016874;ligase activity;2.10826831558682e-18!GO:0006464;protein modification process;1.14175615100347e-17!GO:0031980;mitochondrial lumen;3.51046604310945e-17!GO:0005759;mitochondrial matrix;3.51046604310945e-17!GO:0005524;ATP binding;3.78759029912974e-17!GO:0042981;regulation of apoptosis;4.66738655286444e-17!GO:0043067;regulation of programmed cell death;8.3463643869594e-17!GO:0012505;endomembrane system;1.18471154951954e-16!GO:0000502;proteasome complex (sensu Eukaryota);1.94719079466606e-16!GO:0008135;translation factor activity, nucleic acid binding;1.98516265320359e-16!GO:0032559;adenyl ribonucleotide binding;1.99443839298151e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;2.46603948493308e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;2.77520983663706e-16!GO:0006605;protein targeting;2.84510621402987e-16!GO:0019941;modification-dependent protein catabolic process;3.15323725712426e-16!GO:0043632;modification-dependent macromolecule catabolic process;3.15323725712426e-16!GO:0043687;post-translational protein modification;5.21504378317112e-16!GO:0008134;transcription factor binding;5.46379914233613e-16!GO:0006511;ubiquitin-dependent protein catabolic process;6.32301544544327e-16!GO:0044257;cellular protein catabolic process;7.20034730090907e-16!GO:0043285;biopolymer catabolic process;7.69961676211459e-16!GO:0030554;adenyl nucleotide binding;9.47866361223565e-16!GO:0006457;protein folding;1.2349261154846e-15!GO:0005730;nucleolus;1.25424954351552e-15!GO:0000278;mitotic cell cycle;1.25612916812116e-15!GO:0006323;DNA packaging;1.32332253622527e-15!GO:0016604;nuclear body;2.01593404899408e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);3.73335471694611e-15!GO:0009057;macromolecule catabolic process;3.9182689623232e-15!GO:0005746;mitochondrial respiratory chain;3.98477920288093e-15!GO:0048770;pigment granule;7.67972120859008e-15!GO:0042470;melanosome;7.67972120859008e-15!GO:0006913;nucleocytoplasmic transport;1.42951510359173e-14!GO:0042623;ATPase activity, coupled;1.42951510359173e-14!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.0766170972507e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.15507886285857e-14!GO:0051169;nuclear transport;2.87168083477267e-14!GO:0016887;ATPase activity;3.00392189850211e-14!GO:0050136;NADH dehydrogenase (quinone) activity;5.04442042367077e-14!GO:0003954;NADH dehydrogenase activity;5.04442042367077e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;5.04442042367077e-14!GO:0009719;response to endogenous stimulus;6.95695184034807e-14!GO:0000398;nuclear mRNA splicing, via spliceosome;1.11886297696427e-13!GO:0000375;RNA splicing, via transesterification reactions;1.11886297696427e-13!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.11886297696427e-13!GO:0044248;cellular catabolic process;2.20860714458708e-13!GO:0065004;protein-DNA complex assembly;2.64638292463539e-13!GO:0006413;translational initiation;2.94698505830181e-13!GO:0006333;chromatin assembly or disassembly;4.15404126790127e-13!GO:0005635;nuclear envelope;4.50521504117642e-13!GO:0000087;M phase of mitotic cell cycle;4.561840221918e-13!GO:0003743;translation initiation factor activity;5.06651954973881e-13!GO:0051726;regulation of cell cycle;6.29663414290419e-13!GO:0007067;mitosis;7.66152542974634e-13!GO:0022403;cell cycle phase;7.89812465279376e-13!GO:0000074;regulation of progression through cell cycle;1.05411703521063e-12!GO:0042775;organelle ATP synthesis coupled electron transport;1.22528677564206e-12!GO:0042773;ATP synthesis coupled electron transport;1.22528677564206e-12!GO:0005761;mitochondrial ribosome;1.54551580956777e-12!GO:0000313;organellar ribosome;1.54551580956777e-12!GO:0000785;chromatin;1.71171799861496e-12!GO:0030163;protein catabolic process;1.90426279515786e-12!GO:0016607;nuclear speck;2.72759593876224e-12!GO:0030964;NADH dehydrogenase complex (quinone);4.12755783951297e-12!GO:0045271;respiratory chain complex I;4.12755783951297e-12!GO:0005747;mitochondrial respiratory chain complex I;4.12755783951297e-12!GO:0050794;regulation of cellular process;5.08333546607292e-12!GO:0031965;nuclear membrane;6.68753976522048e-12!GO:0048193;Golgi vesicle transport;1.14941209363465e-11!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.24194994048268e-11!GO:0006446;regulation of translational initiation;1.90684030610161e-11!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.75054755670545e-11!GO:0051301;cell division;2.78627145100048e-11!GO:0006793;phosphorus metabolic process;3.43490898221485e-11!GO:0006796;phosphate metabolic process;3.43490898221485e-11!GO:0051082;unfolded protein binding;3.54760475485426e-11!GO:0005794;Golgi apparatus;4.26111244796581e-11!GO:0004386;helicase activity;4.31926083031578e-11!GO:0044432;endoplasmic reticulum part;6.01521638138159e-11!GO:0000279;M phase;6.45995333960291e-11!GO:0005783;endoplasmic reticulum;7.4615933370578e-11!GO:0007249;I-kappaB kinase/NF-kappaB cascade;9.38493927339568e-11!GO:0044453;nuclear membrane part;1.56883870523036e-10!GO:0008639;small protein conjugating enzyme activity;1.6857829637636e-10!GO:0006334;nucleosome assembly;1.7466572962118e-10!GO:0051186;cofactor metabolic process;1.80056452727168e-10!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.53326859137449e-10!GO:0019787;small conjugating protein ligase activity;2.65727449436639e-10!GO:0042254;ribosome biogenesis and assembly;3.10172735265437e-10!GO:0004842;ubiquitin-protein ligase activity;3.17112881067358e-10!GO:0017038;protein import;3.35716899676293e-10!GO:0051246;regulation of protein metabolic process;3.43889999577485e-10!GO:0008026;ATP-dependent helicase activity;3.62466962851027e-10!GO:0016568;chromatin modification;4.66499553722944e-10!GO:0006260;DNA replication;4.76528893400559e-10!GO:0031497;chromatin assembly;5.92889942782316e-10!GO:0016192;vesicle-mediated transport;8.56151384505447e-10!GO:0016787;hydrolase activity;1.14468591830488e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.14592373226977e-09!GO:0043069;negative regulation of programmed cell death;1.17000128981993e-09!GO:0006916;anti-apoptosis;1.50874492536744e-09!GO:0043066;negative regulation of apoptosis;1.67468806825868e-09!GO:0003712;transcription cofactor activity;1.74674926885537e-09!GO:0007243;protein kinase cascade;1.83035576716745e-09!GO:0016310;phosphorylation;2.01335529178816e-09!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;2.19991378088343e-09!GO:0019829;cation-transporting ATPase activity;2.44873160160531e-09!GO:0008565;protein transporter activity;2.79054941449175e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;2.93133540501883e-09!GO:0043566;structure-specific DNA binding;2.98751249964413e-09!GO:0005789;endoplasmic reticulum membrane;3.22364823154883e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;6.57610040715323e-09!GO:0009259;ribonucleotide metabolic process;7.58754547987986e-09!GO:0005643;nuclear pore;9.49923637886978e-09!GO:0050657;nucleic acid transport;1.08803174864919e-08!GO:0051236;establishment of RNA localization;1.08803174864919e-08!GO:0050658;RNA transport;1.08803174864919e-08!GO:0006403;RNA localization;1.24974390242111e-08!GO:0006917;induction of apoptosis;1.3802425660742e-08!GO:0005839;proteasome core complex (sensu Eukaryota);1.45881107354845e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.73855977393636e-08!GO:0016881;acid-amino acid ligase activity;1.77631824347383e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.00778932741958e-08!GO:0012502;induction of programmed cell death;2.40813802891281e-08!GO:0048523;negative regulation of cellular process;2.40813802891281e-08!GO:0006164;purine nucleotide biosynthetic process;2.63082105487384e-08!GO:0006163;purine nucleotide metabolic process;2.7608614675821e-08!GO:0009260;ribonucleotide biosynthetic process;2.91344436551341e-08!GO:0003697;single-stranded DNA binding;3.78689338124923e-08!GO:0005768;endosome;3.97844822789097e-08!GO:0006732;coenzyme metabolic process;4.36256269041549e-08!GO:0009055;electron carrier activity;5.33924290093556e-08!GO:0043065;positive regulation of apoptosis;5.71675129645913e-08!GO:0009152;purine ribonucleotide biosynthetic process;6.20691464445217e-08!GO:0015078;hydrogen ion transmembrane transporter activity;6.45003061111468e-08!GO:0051170;nuclear import;6.52887572797295e-08!GO:0065002;intracellular protein transport across a membrane;6.52887572797295e-08!GO:0065009;regulation of a molecular function;6.64922798226025e-08!GO:0009150;purine ribonucleotide metabolic process;6.76431469405069e-08!GO:0006399;tRNA metabolic process;7.51306906580376e-08!GO:0004298;threonine endopeptidase activity;7.89755278012462e-08!GO:0043068;positive regulation of programmed cell death;8.86220642346472e-08!GO:0015986;ATP synthesis coupled proton transport;9.99741056728462e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;9.99741056728462e-08!GO:0019222;regulation of metabolic process;1.05454794002466e-07!GO:0030532;small nuclear ribonucleoprotein complex;1.24872528153163e-07!GO:0006606;protein import into nucleus;1.29171779480915e-07!GO:0050789;regulation of biological process;1.46798951669193e-07!GO:0016740;transferase activity;2.09590757596944e-07!GO:0032446;protein modification by small protein conjugation;2.19699858682396e-07!GO:0046930;pore complex;2.3928713600968e-07!GO:0048519;negative regulation of biological process;2.96936122814141e-07!GO:0006888;ER to Golgi vesicle-mediated transport;3.13806795478969e-07!GO:0009056;catabolic process;3.1539143076199e-07!GO:0000786;nucleosome;3.22888461565799e-07!GO:0051028;mRNA transport;3.88999887133346e-07!GO:0048522;positive regulation of cellular process;4.80779236987174e-07!GO:0016567;protein ubiquitination;5.56186491410046e-07!GO:0019899;enzyme binding;5.65167654657197e-07!GO:0048475;coated membrane;5.70836092373049e-07!GO:0030117;membrane coat;5.70836092373049e-07!GO:0007242;intracellular signaling cascade;6.32741953909498e-07!GO:0051188;cofactor biosynthetic process;6.54293469332613e-07!GO:0016779;nucleotidyltransferase activity;6.66527953174566e-07!GO:0009060;aerobic respiration;6.69582611303942e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;8.01054648789328e-07!GO:0006754;ATP biosynthetic process;8.26993588309252e-07!GO:0006753;nucleoside phosphate metabolic process;8.26993588309252e-07!GO:0006366;transcription from RNA polymerase II promoter;8.47713824996598e-07!GO:0000245;spliceosome assembly;1.02012299729464e-06!GO:0016469;proton-transporting two-sector ATPase complex;1.02203091411903e-06!GO:0003713;transcription coactivator activity;1.0490721737207e-06!GO:0016072;rRNA metabolic process;1.14433407933172e-06!GO:0030120;vesicle coat;1.14438330043421e-06!GO:0030662;coated vesicle membrane;1.14438330043421e-06!GO:0031324;negative regulation of cellular metabolic process;1.19877129143481e-06!GO:0005813;centrosome;1.27383936462246e-06!GO:0006310;DNA recombination;1.29755205155569e-06!GO:0009142;nucleoside triphosphate biosynthetic process;1.34615623789855e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.34615623789855e-06!GO:0016563;transcription activator activity;1.38408457987912e-06!GO:0006364;rRNA processing;1.4046800605781e-06!GO:0005793;ER-Golgi intermediate compartment;1.4046800605781e-06!GO:0005773;vacuole;1.51965756100459e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.69454354608599e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.69454354608599e-06!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;2.26818513159083e-06!GO:0004812;aminoacyl-tRNA ligase activity;2.26818513159083e-06!GO:0016875;ligase activity, forming carbon-oxygen bonds;2.26818513159083e-06!GO:0005815;microtubule organizing center;2.31523826905312e-06!GO:0008632;apoptotic program;2.4325255187137e-06!GO:0045786;negative regulation of progression through cell cycle;2.52331311688832e-06!GO:0009199;ribonucleoside triphosphate metabolic process;2.59235297910475e-06!GO:0046034;ATP metabolic process;2.7415651168166e-06!GO:0015630;microtubule cytoskeleton;2.81426878450208e-06!GO:0000323;lytic vacuole;2.84244536062004e-06!GO:0005764;lysosome;2.84244536062004e-06!GO:0009141;nucleoside triphosphate metabolic process;2.99380771669841e-06!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.99380771669841e-06!GO:0006417;regulation of translation;3.16203695312646e-06!GO:0006613;cotranslational protein targeting to membrane;3.16203695312646e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.25537906684496e-06!GO:0009144;purine nucleoside triphosphate metabolic process;3.25537906684496e-06!GO:0043038;amino acid activation;3.35913114897356e-06!GO:0006418;tRNA aminoacylation for protein translation;3.35913114897356e-06!GO:0043039;tRNA aminoacylation;3.35913114897356e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;3.94397348200584e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;4.1317887372211e-06!GO:0015399;primary active transmembrane transporter activity;4.1317887372211e-06!GO:0031323;regulation of cellular metabolic process;4.18470747155825e-06!GO:0045259;proton-transporting ATP synthase complex;4.3728675414718e-06!GO:0045333;cellular respiration;4.69683555119625e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;5.48095191981302e-06!GO:0005525;GTP binding;6.81412329782952e-06!GO:0006461;protein complex assembly;8.99872750650857e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;9.47336396573929e-06!GO:0009892;negative regulation of metabolic process;9.94759663044688e-06!GO:0016564;transcription repressor activity;1.0631875572508e-05!GO:0007005;mitochondrion organization and biogenesis;1.09923020730278e-05!GO:0000151;ubiquitin ligase complex;1.11894780105721e-05!GO:0051168;nuclear export;1.52417534471071e-05!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.58854598040451e-05!GO:0006612;protein targeting to membrane;1.78692496062172e-05!GO:0004674;protein serine/threonine kinase activity;1.95158425355477e-05!GO:0003724;RNA helicase activity;2.17428426858478e-05!GO:0009108;coenzyme biosynthetic process;2.2278578750715e-05!GO:0005819;spindle;2.30500722429258e-05!GO:0042110;T cell activation;2.85945966135609e-05!GO:0003690;double-stranded DNA binding;2.96884695193993e-05!GO:0005770;late endosome;3.24225329954283e-05!GO:0006099;tricarboxylic acid cycle;3.27823478338675e-05!GO:0046356;acetyl-CoA catabolic process;3.27823478338675e-05!GO:0031326;regulation of cellular biosynthetic process;3.36981551894848e-05!GO:0006752;group transfer coenzyme metabolic process;3.47894010481873e-05!GO:0006401;RNA catabolic process;3.70365400244782e-05!GO:0006261;DNA-dependent DNA replication;4.2594691663998e-05!GO:0016363;nuclear matrix;4.32097408785514e-05!GO:0003924;GTPase activity;4.36365429853202e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.65890293595694e-05!GO:0044431;Golgi apparatus part;5.08546561340214e-05!GO:0009967;positive regulation of signal transduction;5.39350232585232e-05!GO:0000075;cell cycle checkpoint;5.70214902617396e-05!GO:0005798;Golgi-associated vesicle;6.38182496089564e-05!GO:0048518;positive regulation of biological process;6.51783181310447e-05!GO:0043492;ATPase activity, coupled to movement of substances;7.22144208173605e-05!GO:0050790;regulation of catalytic activity;7.35081253352561e-05!GO:0005762;mitochondrial large ribosomal subunit;7.42216599475191e-05!GO:0000315;organellar large ribosomal subunit;7.42216599475191e-05!GO:0005852;eukaryotic translation initiation factor 3 complex;8.22053261762903e-05!GO:0065007;biological regulation;8.51038599301196e-05!GO:0006084;acetyl-CoA metabolic process;8.65035430443949e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;8.73449091746097e-05!GO:0032561;guanyl ribonucleotide binding;9.2113944735171e-05!GO:0019001;guanyl nucleotide binding;9.2113944735171e-05!GO:0008234;cysteine-type peptidase activity;9.55518468535801e-05!GO:0006350;transcription;9.72467366650149e-05!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000104479950154493!GO:0006402;mRNA catabolic process;0.000109518645106057!GO:0000775;chromosome, pericentric region;0.000121677924257856!GO:0044440;endosomal part;0.000127798411719344!GO:0010008;endosome membrane;0.000127798411719344!GO:0005885;Arp2/3 protein complex;0.000154690713398022!GO:0009117;nucleotide metabolic process;0.000178067485987644!GO:0051427;hormone receptor binding;0.000186979455085143!GO:0009615;response to virus;0.000195334620417315!GO:0016481;negative regulation of transcription;0.000198596870943629!GO:0043021;ribonucleoprotein binding;0.000198596870943629!GO:0043623;cellular protein complex assembly;0.000221661753831373!GO:0051187;cofactor catabolic process;0.000237716135341551!GO:0008654;phospholipid biosynthetic process;0.000242613212548059!GO:0009109;coenzyme catabolic process;0.000249657618676332!GO:0010468;regulation of gene expression;0.000252070810350849!GO:0030384;phosphoinositide metabolic process;0.000283037034443553!GO:0019843;rRNA binding;0.000297680817505265!GO:0015992;proton transport;0.00029908606905891!GO:0005667;transcription factor complex;0.000314877567703787!GO:0008186;RNA-dependent ATPase activity;0.000316684993531657!GO:0006818;hydrogen transport;0.000331960268810005!GO:0006302;double-strand break repair;0.000367656599646128!GO:0035257;nuclear hormone receptor binding;0.000373609731453759!GO:0006891;intra-Golgi vesicle-mediated transport;0.000381796885718503!GO:0009889;regulation of biosynthetic process;0.000386806695171524!GO:0007088;regulation of mitosis;0.000389674367296934!GO:0005657;replication fork;0.00041532032138798!GO:0051325;interphase;0.00050673837623965!GO:0003899;DNA-directed RNA polymerase activity;0.000510811262215047!GO:0006352;transcription initiation;0.000516045839817669!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000519498589006838!GO:0003729;mRNA binding;0.000584326961762273!GO:0006650;glycerophospholipid metabolic process;0.000598433462166546!GO:0046649;lymphocyte activation;0.000623898299259282!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000625580094468109!GO:0051329;interphase of mitotic cell cycle;0.000688799322589265!GO:0003678;DNA helicase activity;0.000691190338144958!GO:0003684;damaged DNA binding;0.000698020479818956!GO:0001772;immunological synapse;0.000708094094712118!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000712237886273693!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000723046399656742!GO:0007264;small GTPase mediated signal transduction;0.000754100241577181!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000794124275515103!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000819580095047656!GO:0031982;vesicle;0.000835934811664978!GO:0051252;regulation of RNA metabolic process;0.000839534500274305!GO:0000139;Golgi membrane;0.000923025391721988!GO:0004004;ATP-dependent RNA helicase activity;0.000923025391721988!GO:0046489;phosphoinositide biosynthetic process;0.000964956647141944!GO:0042802;identical protein binding;0.000966245295211276!GO:0016853;isomerase activity;0.00100106023957436!GO:0030658;transport vesicle membrane;0.00101842501451108!GO:0008094;DNA-dependent ATPase activity;0.00103446109061466!GO:0060090;molecular adaptor activity;0.0010673316284393!GO:0000314;organellar small ribosomal subunit;0.00113428641460814!GO:0005763;mitochondrial small ribosomal subunit;0.00113428641460814!GO:0005741;mitochondrial outer membrane;0.00117932670122181!GO:0004518;nuclease activity;0.00118085379282611!GO:0048500;signal recognition particle;0.00119540519239334!GO:0006289;nucleotide-excision repair;0.00121066764170608!GO:0051249;regulation of lymphocyte activation;0.00125933932013152!GO:0022415;viral reproductive process;0.00128965788628933!GO:0007051;spindle organization and biogenesis;0.00129459518414008!GO:0019867;outer membrane;0.00132292339373535!GO:0048468;cell development;0.00136110746819055!GO:0050865;regulation of cell activation;0.00136110746819055!GO:0005637;nuclear inner membrane;0.00137125670857846!GO:0000776;kinetochore;0.00138019403793713!GO:0030118;clathrin coat;0.00139675599340772!GO:0005769;early endosome;0.0014078630063721!GO:0006414;translational elongation;0.00142242297946475!GO:0051251;positive regulation of lymphocyte activation;0.00151427906184235!GO:0051052;regulation of DNA metabolic process;0.00165157203495825!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0017129434459956!GO:0006383;transcription from RNA polymerase III promoter;0.00174212392997853!GO:0031968;organelle outer membrane;0.00177623006240424!GO:0008270;zinc ion binding;0.00179745135449915!GO:0006611;protein export from nucleus;0.00181480711144331!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.0019307862774782!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.0019307862774782!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.0019307862774782!GO:0007006;mitochondrial membrane organization and biogenesis;0.00193611288706713!GO:0045454;cell redox homeostasis;0.002010159915397!GO:0046822;regulation of nucleocytoplasmic transport;0.002010159915397!GO:0030660;Golgi-associated vesicle membrane;0.00206283211242437!GO:0007093;mitotic cell cycle checkpoint;0.00208495265353954!GO:0008624;induction of apoptosis by extracellular signals;0.00216087047980554!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00217348548282087!GO:0045047;protein targeting to ER;0.00217348548282087!GO:0031988;membrane-bound vesicle;0.00219205606146161!GO:0046474;glycerophospholipid biosynthetic process;0.00220647156179002!GO:0050863;regulation of T cell activation;0.00230151664123642!GO:0003714;transcription corepressor activity;0.00235456184567125!GO:0043681;protein import into mitochondrion;0.00247854369722413!GO:0016251;general RNA polymerase II transcription factor activity;0.00249897895161956!GO:0016197;endosome transport;0.00249897895161956!GO:0031410;cytoplasmic vesicle;0.00271560998489812!GO:0051223;regulation of protein transport;0.00287028233563565!GO:0051092;activation of NF-kappaB transcription factor;0.00296068850869986!GO:0032940;secretion by cell;0.00299365268677128!GO:0008312;7S RNA binding;0.00299453864991152!GO:0005048;signal sequence binding;0.00300299408635084!GO:0031072;heat shock protein binding;0.00317256591212187!GO:0004527;exonuclease activity;0.00326192852587734!GO:0047485;protein N-terminus binding;0.00345513779097324!GO:0051087;chaperone binding;0.00350091927820033!GO:0000287;magnesium ion binding;0.00373712147906066!GO:0008637;apoptotic mitochondrial changes;0.00373712147906066!GO:0032774;RNA biosynthetic process;0.00380268515566027!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00380268515566027!GO:0007059;chromosome segregation;0.00382239864074091!GO:0003711;transcription elongation regulator activity;0.00385056255731947!GO:0008168;methyltransferase activity;0.00391111563130375!GO:0051789;response to protein stimulus;0.00409381455290643!GO:0006986;response to unfolded protein;0.00409381455290643!GO:0051090;regulation of transcription factor activity;0.00409381455290643!GO:0000209;protein polyubiquitination;0.00413256280820816!GO:0045321;leukocyte activation;0.00442456233839541!GO:0006338;chromatin remodeling;0.00443536585999457!GO:0051920;peroxiredoxin activity;0.00447084903243244!GO:0006351;transcription, DNA-dependent;0.00450044874403326!GO:0016741;transferase activity, transferring one-carbon groups;0.00461542474961454!GO:0031902;late endosome membrane;0.00461987087683845!GO:0019210;kinase inhibitor activity;0.00477643910150718!GO:0032259;methylation;0.00481039488022403!GO:0005774;vacuolar membrane;0.00518444443311095!GO:0043414;biopolymer methylation;0.00528550014430324!GO:0004177;aminopeptidase activity;0.00528622338004508!GO:0043488;regulation of mRNA stability;0.00539437128993192!GO:0043487;regulation of RNA stability;0.00539437128993192!GO:0007050;cell cycle arrest;0.00541496320075767!GO:0042101;T cell receptor complex;0.00545662773360884!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00546904396739573!GO:0016788;hydrolase activity, acting on ester bonds;0.0054886755280002!GO:0015631;tubulin binding;0.00550445955899685!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00553643205601484!GO:0005684;U2-dependent spliceosome;0.00558487583116882!GO:0031252;leading edge;0.00576821949676462!GO:0045045;secretory pathway;0.00576821949676462!GO:0016023;cytoplasmic membrane-bound vesicle;0.00583742734424506!GO:0004860;protein kinase inhibitor activity;0.00583742734424506!GO:0016859;cis-trans isomerase activity;0.00584639057524764!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.006025237675215!GO:0048471;perinuclear region of cytoplasm;0.00605572119906183!GO:0003746;translation elongation factor activity;0.00623905828522588!GO:0031124;mRNA 3'-end processing;0.00627909599143331!GO:0019901;protein kinase binding;0.00629854898477832!GO:0003677;DNA binding;0.00636135784980288!GO:0008033;tRNA processing;0.0063763540086594!GO:0046966;thyroid hormone receptor binding;0.00637650463128781!GO:0030518;steroid hormone receptor signaling pathway;0.00641325931584287!GO:0006091;generation of precursor metabolites and energy;0.00643721150754325!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00643721150754325!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00646090907834578!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00646090907834578!GO:0006607;NLS-bearing substrate import into nucleus;0.00662680621790748!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00674265260735004!GO:0004576;oligosaccharyl transferase activity;0.00681804390085953!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00686379858940775!GO:0016584;nucleosome positioning;0.00691757305507512!GO:0050870;positive regulation of T cell activation;0.00703279883185621!GO:0045076;regulation of interleukin-2 biosynthetic process;0.00703279883185621!GO:0051336;regulation of hydrolase activity;0.00713858287549378!GO:0045449;regulation of transcription;0.00721465459676812!GO:0003682;chromatin binding;0.00731798802450999!GO:0022890;inorganic cation transmembrane transporter activity;0.00732071708458687!GO:0008250;oligosaccharyl transferase complex;0.00753995278387681!GO:0005765;lysosomal membrane;0.00757876161004436!GO:0016791;phosphoric monoester hydrolase activity;0.00769457698813569!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0080380287541841!GO:0007265;Ras protein signal transduction;0.00826722905087439!GO:0032200;telomere organization and biogenesis;0.00827619142749789!GO:0000723;telomere maintenance;0.00827619142749789!GO:0009165;nucleotide biosynthetic process;0.00861071128956921!GO:0008047;enzyme activator activity;0.00873622021711565!GO:0030663;COPI coated vesicle membrane;0.0090476522889938!GO:0030126;COPI vesicle coat;0.0090476522889938!GO:0016301;kinase activity;0.00925207251742712!GO:0019079;viral genome replication;0.00928350913058667!GO:0006405;RNA export from nucleus;0.00931905083667356!GO:0022411;cellular component disassembly;0.00934826017465303!GO:0045892;negative regulation of transcription, DNA-dependent;0.00937276967860438!GO:0006950;response to stress;0.00944978906159917!GO:0051059;NF-kappaB binding;0.0097802003762821!GO:0051098;regulation of binding;0.0103162094278594!GO:0000049;tRNA binding;0.0103610773586302!GO:0000082;G1/S transition of mitotic cell cycle;0.0105574109663892!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0105574109663892!GO:0015002;heme-copper terminal oxidase activity;0.0105574109663892!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0105574109663892!GO:0004129;cytochrome-c oxidase activity;0.0105574109663892!GO:0008022;protein C-terminus binding;0.0105574109663892!GO:0019955;cytokine binding;0.0105614222119134!GO:0030137;COPI-coated vesicle;0.0105681186645476!GO:0004003;ATP-dependent DNA helicase activity;0.0105734452261462!GO:0007034;vacuolar transport;0.0106247268690189!GO:0044452;nucleolar part;0.0108703954227581!GO:0030119;AP-type membrane coat adaptor complex;0.0112045517960529!GO:0006914;autophagy;0.0112342622708941!GO:0051235;maintenance of localization;0.0112606058683142!GO:0030127;COPII vesicle coat;0.0113271978119089!GO:0012507;ER to Golgi transport vesicle membrane;0.0113271978119089!GO:0044437;vacuolar part;0.011335531034499!GO:0007052;mitotic spindle organization and biogenesis;0.0115101984355875!GO:0019783;small conjugating protein-specific protease activity;0.0115152784392219!GO:0006497;protein amino acid lipidation;0.0116705478662577!GO:0030521;androgen receptor signaling pathway;0.0117522226844841!GO:0016311;dephosphorylation;0.0118306008634555!GO:0007259;JAK-STAT cascade;0.0119413127643045!GO:0004843;ubiquitin-specific protease activity;0.0121108039376001!GO:0000339;RNA cap binding;0.0121671279592039!GO:0016605;PML body;0.0122104015730154!GO:0033116;ER-Golgi intermediate compartment membrane;0.0123634914587146!GO:0046467;membrane lipid biosynthetic process;0.0124074081995146!GO:0030867;rough endoplasmic reticulum membrane;0.012439522121424!GO:0016272;prefoldin complex;0.0124937083471372!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0126329823362053!GO:0005070;SH3/SH2 adaptor activity;0.0126381116505856!GO:0030134;ER to Golgi transport vesicle;0.0126843700091091!GO:0008139;nuclear localization sequence binding;0.0128645751536356!GO:0019900;kinase binding;0.0130876951883485!GO:0006007;glucose catabolic process;0.013094111963305!GO:0045069;regulation of viral genome replication;0.013094111963305!GO:0031123;RNA 3'-end processing;0.013094111963305!GO:0018196;peptidyl-asparagine modification;0.0131337414638627!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0131337414638627!GO:0046983;protein dimerization activity;0.0132608265462564!GO:0051539;4 iron, 4 sulfur cluster binding;0.0134129549001844!GO:0006284;base-excision repair;0.0135557992622334!GO:0043621;protein self-association;0.0135668311910721!GO:0018193;peptidyl-amino acid modification;0.0136327210961898!GO:0006506;GPI anchor biosynthetic process;0.0136336618614543!GO:0006376;mRNA splice site selection;0.0138270343002344!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0138270343002344!GO:0030176;integral to endoplasmic reticulum membrane;0.0145825723284075!GO:0030131;clathrin adaptor complex;0.0145871139866503!GO:0005869;dynactin complex;0.0147298835702147!GO:0042393;histone binding;0.014802308693699!GO:0033673;negative regulation of kinase activity;0.014802308693699!GO:0006469;negative regulation of protein kinase activity;0.014802308693699!GO:0006505;GPI anchor metabolic process;0.0150213133777726!GO:0048487;beta-tubulin binding;0.0155015719240218!GO:0042770;DNA damage response, signal transduction;0.0164246196700646!GO:0006839;mitochondrial transport;0.0165342096878647!GO:0042094;interleukin-2 biosynthetic process;0.016619176716984!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0175251235523135!GO:0005788;endoplasmic reticulum lumen;0.0175597617204817!GO:0030125;clathrin vesicle coat;0.0177050088771888!GO:0030665;clathrin coated vesicle membrane;0.0177050088771888!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0177141730867922!GO:0004221;ubiquitin thiolesterase activity;0.0177806396402421!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0179409094189319!GO:0001836;release of cytochrome c from mitochondria;0.0179872192590656!GO:0019058;viral infectious cycle;0.018065333875852!GO:0051881;regulation of mitochondrial membrane potential;0.0181384050044339!GO:0004197;cysteine-type endopeptidase activity;0.0184700613475035!GO:0005521;lamin binding;0.0185367220733439!GO:0000018;regulation of DNA recombination;0.0187307129686404!GO:0006626;protein targeting to mitochondrion;0.0187307129686404!GO:0051540;metal cluster binding;0.0189045575170215!GO:0051536;iron-sulfur cluster binding;0.0189045575170215!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0192455347865557!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0192455347865557!GO:0044438;microbody part;0.0193291156533993!GO:0044439;peroxisomal part;0.0193291156533993!GO:0030880;RNA polymerase complex;0.0194438776650244!GO:0045086;positive regulation of interleukin-2 biosynthetic process;0.019510023611218!GO:0030522;intracellular receptor-mediated signaling pathway;0.0197293401240446!GO:0051348;negative regulation of transferase activity;0.0201443212412712!GO:0015980;energy derivation by oxidation of organic compounds;0.020200888107283!GO:0000738;DNA catabolic process, exonucleolytic;0.0202749028326755!GO:0032508;DNA duplex unwinding;0.0203186881978546!GO:0032392;DNA geometric change;0.0203186881978546!GO:0043281;regulation of caspase activity;0.0206739853842323!GO:0043022;ribosome binding;0.0209568597144713!GO:0005669;transcription factor TFIID complex;0.0210774081256044!GO:0004722;protein serine/threonine phosphatase activity;0.0213691583651879!GO:0045936;negative regulation of phosphate metabolic process;0.0224080354774128!GO:0006378;mRNA polyadenylation;0.0226868318973772!GO:0004532;exoribonuclease activity;0.023223620926745!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.023223620926745!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.0233079869008907!GO:0022406;membrane docking;0.0233451357564415!GO:0048278;vesicle docking;0.0233451357564415!GO:0040029;regulation of gene expression, epigenetic;0.0234740434722543!GO:0031625;ubiquitin protein ligase binding;0.0235314386674157!GO:0033367;protein localization in mast cell secretory granule;0.0237639127533547!GO:0033365;protein localization in organelle;0.0237639127533547!GO:0033371;T cell secretory granule organization and biogenesis;0.0237639127533547!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0237639127533547!GO:0033375;protease localization in T cell secretory granule;0.0237639127533547!GO:0042629;mast cell granule;0.0237639127533547!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0237639127533547!GO:0033364;mast cell secretory granule organization and biogenesis;0.0237639127533547!GO:0033380;granzyme B localization in T cell secretory granule;0.0237639127533547!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0237639127533547!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0237639127533547!GO:0033368;protease localization in mast cell secretory granule;0.0237639127533547!GO:0033366;protein localization in secretory granule;0.0237639127533547!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0237639127533547!GO:0033374;protein localization in T cell secretory granule;0.0237639127533547!GO:0030258;lipid modification;0.0240507559124406!GO:0030133;transport vesicle;0.0245968677226566!GO:0009116;nucleoside metabolic process;0.0247503007224186!GO:0004721;phosphoprotein phosphatase activity;0.0247921949374637!GO:0031903;microbody membrane;0.0247921949374637!GO:0005778;peroxisomal membrane;0.0247921949374637!GO:0030217;T cell differentiation;0.0249062126201333!GO:0008629;induction of apoptosis by intracellular signals;0.0251428230911171!GO:0000781;chromosome, telomeric region;0.0251428230911171!GO:0035258;steroid hormone receptor binding;0.0253046667301161!GO:0008287;protein serine/threonine phosphatase complex;0.0253046667301161!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0262214731067923!GO:0045792;negative regulation of cell size;0.0262930354525473!GO:0016790;thiolester hydrolase activity;0.0263139534590622!GO:0003988;acetyl-CoA C-acyltransferase activity;0.027039992466104!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0273420001462958!GO:0010257;NADH dehydrogenase complex assembly;0.0273420001462958!GO:0033108;mitochondrial respiratory chain complex assembly;0.0273420001462958!GO:0019976;interleukin-2 binding;0.0274436035129864!GO:0004911;interleukin-2 receptor activity;0.0274436035129864!GO:0006904;vesicle docking during exocytosis;0.0274939859240031!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0275430903781199!GO:0002440;production of molecular mediator of immune response;0.0275926609108378!GO:0006518;peptide metabolic process;0.0278132499177874!GO:0046483;heterocycle metabolic process;0.0281336024720008!GO:0008097;5S rRNA binding;0.0282191855678798!GO:0008408;3'-5' exonuclease activity;0.0287799527934108!GO:0050852;T cell receptor signaling pathway;0.02920836594206!GO:0051338;regulation of transferase activity;0.0292864328081306!GO:0042608;T cell receptor binding;0.0293093647950731!GO:0016860;intramolecular oxidoreductase activity;0.0293333467409873!GO:0042289;MHC class II protein binding;0.0293764330938151!GO:0046426;negative regulation of JAK-STAT cascade;0.0294077231602676!GO:0030695;GTPase regulator activity;0.0294584126897757!GO:0015923;mannosidase activity;0.0297316067192498!GO:0046914;transition metal ion binding;0.0298231680152435!GO:0050811;GABA receptor binding;0.0299264234779162!GO:0042158;lipoprotein biosynthetic process;0.0299330003528423!GO:0002521;leukocyte differentiation;0.0300192178309288!GO:0009124;nucleoside monophosphate biosynthetic process;0.0302555720305526!GO:0009123;nucleoside monophosphate metabolic process;0.0302555720305526!GO:0043433;negative regulation of transcription factor activity;0.0303674052166239!GO:0043596;nuclear replication fork;0.030614937691379!GO:0006144;purine base metabolic process;0.0308093478118824!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0311473377830229!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0311473377830229!GO:0019904;protein domain specific binding;0.0311473377830229!GO:0030308;negative regulation of cell growth;0.0311473377830229!GO:0030833;regulation of actin filament polymerization;0.031181246544721!GO:0009112;nucleobase metabolic process;0.0317187501013037!GO:0005095;GTPase inhibitor activity;0.0319155178905977!GO:0048524;positive regulation of viral reproduction;0.0323519297043276!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0325815856985981!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0325815856985981!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0325815856985981!GO:0005784;translocon complex;0.0327074580301011!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0327324060324574!GO:0000428;DNA-directed RNA polymerase complex;0.0327324060324574!GO:0006595;polyamine metabolic process;0.0328346580861415!GO:0048002;antigen processing and presentation of peptide antigen;0.0330117196745203!GO:0033157;regulation of intracellular protein transport;0.0330639605656882!GO:0042306;regulation of protein import into nucleus;0.0330639605656882!GO:0008320;protein transmembrane transporter activity;0.0334435520059096!GO:0016569;covalent chromatin modification;0.0336303346386785!GO:0005791;rough endoplasmic reticulum;0.0336370432882627!GO:0017134;fibroblast growth factor binding;0.0336370432882627!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0336370432882627!GO:0006778;porphyrin metabolic process;0.0341032300201711!GO:0033013;tetrapyrrole metabolic process;0.0341032300201711!GO:0000922;spindle pole;0.0341447731685834!GO:0006509;membrane protein ectodomain proteolysis;0.0342113102703553!GO:0033619;membrane protein proteolysis;0.0342113102703553!GO:0005996;monosaccharide metabolic process;0.0345860983095631!GO:0046365;monosaccharide catabolic process;0.0346319135598613!GO:0045185;maintenance of protein localization;0.0346473577670988!GO:0006465;signal peptide processing;0.0348607675513739!GO:0008538;proteasome activator activity;0.0348607675513739!GO:0019318;hexose metabolic process;0.0348607675513739!GO:0009966;regulation of signal transduction;0.0357421772521173!GO:0006672;ceramide metabolic process;0.0360348387408636!GO:0005832;chaperonin-containing T-complex;0.0362355096873821!GO:0006919;caspase activation;0.0365025515029823!GO:0006268;DNA unwinding during replication;0.0369347723452465!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0372012439191615!GO:0006487;protein amino acid N-linked glycosylation;0.0379093063023383!GO:0008017;microtubule binding;0.0379350912145791!GO:0006355;regulation of transcription, DNA-dependent;0.0381423178989756!GO:0046519;sphingoid metabolic process;0.0382007843809268!GO:0016763;transferase activity, transferring pentosyl groups;0.0384025946624756!GO:0007040;lysosome organization and biogenesis;0.0384025946624756!GO:0030132;clathrin coat of coated pit;0.0385300128398341!GO:0043549;regulation of kinase activity;0.0385937983763493!GO:0000228;nuclear chromosome;0.0386788512197871!GO:0004428;inositol or phosphatidylinositol kinase activity;0.0389587980276529!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0390510813778008!GO:0003725;double-stranded RNA binding;0.0390510813778008!GO:0008213;protein amino acid alkylation;0.0391210304693426!GO:0006479;protein amino acid methylation;0.0391210304693426!GO:0005777;peroxisome;0.0391210304693426!GO:0042579;microbody;0.0391210304693426!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.039363417349829!GO:0019220;regulation of phosphate metabolic process;0.0395868493423815!GO:0051174;regulation of phosphorus metabolic process;0.0395868493423815!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0397285900753942!GO:0050792;regulation of viral reproduction;0.0397674370324919!GO:0022884;macromolecule transmembrane transporter activity;0.0397674370324919!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0397674370324919!GO:0008180;signalosome;0.0401961064200477!GO:0016408;C-acyltransferase activity;0.0401961064200477!GO:0000152;nuclear ubiquitin ligase complex;0.0403625776109038!GO:0051452;cellular pH reduction;0.0413521872854213!GO:0051453;regulation of cellular pH;0.0413521872854213!GO:0045851;pH reduction;0.0413521872854213!GO:0006458;'de novo' protein folding;0.0414497480273818!GO:0051084;'de novo' posttranslational protein folding;0.0414497480273818!GO:0000726;non-recombinational repair;0.041528789552627!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.041528789552627!GO:0006984;ER-nuclear signaling pathway;0.0416526342654407!GO:0009161;ribonucleoside monophosphate metabolic process;0.0420854393086995!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0420854393086995!GO:0046979;TAP2 binding;0.0423722646980179!GO:0046977;TAP binding;0.0423722646980179!GO:0046978;TAP1 binding;0.0423722646980179!GO:0016570;histone modification;0.0426053918863394!GO:0006779;porphyrin biosynthetic process;0.0426053918863394!GO:0033014;tetrapyrrole biosynthetic process;0.0426053918863394!GO:0007004;telomere maintenance via telomerase;0.0428593957763234!GO:0046982;protein heterodimerization activity;0.0429717242390975!GO:0042326;negative regulation of phosphorylation;0.0431907038482179!GO:0051287;NAD binding;0.0431907038482179!GO:0007021;tubulin folding;0.0434704293184707!GO:0005031;tumor necrosis factor receptor activity;0.0446062908933011!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0446386598969118!GO:0006013;mannose metabolic process;0.0447484160477944!GO:0005874;microtubule;0.0447484160477944!GO:0008276;protein methyltransferase activity;0.0448909342613238!GO:0007033;vacuole organization and biogenesis;0.0451985077748362!GO:0046164;alcohol catabolic process;0.0453906000493377!GO:0005083;small GTPase regulator activity;0.0454358363058693!GO:0002820;negative regulation of adaptive immune response;0.0455231273981892!GO:0002823;negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0455231273981892!GO:0005876;spindle microtubule;0.0456119572928959!GO:0002378;immunoglobulin biosynthetic process;0.0474080789177155!GO:0001911;negative regulation of leukocyte mediated cytotoxicity;0.0474080789177155!GO:0001915;negative regulation of T cell mediated cytotoxicity;0.0474080789177155!GO:0000059;protein import into nucleus, docking;0.0479998366717685!GO:0004659;prenyltransferase activity;0.048039083207835!GO:0045941;positive regulation of transcription;0.0482339558340997!GO:0031647;regulation of protein stability;0.048623925415511!GO:0043086;negative regulation of catalytic activity;0.0490391530667407!GO:0032507;maintenance of cellular protein localization;0.0490640895452369!GO:0000090;mitotic anaphase;0.0493627178802104!GO:0051322;anaphase;0.0493627178802104!GO:0008625;induction of apoptosis via death domain receptors;0.0493627178802104!GO:0016491;oxidoreductase activity;0.0499771880984487!GO:0042168;heme metabolic process;0.0499771880984487 | |||
|sample_id=11794 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=ELF1,2,4:2.70713384353;RORA:2.3790926365;TLX2:2.37136343263;RUNX1..3:2.2800733944;PAX3,7:2.11491607954;CDX1,2,4:1.95886148893;ETS1,2:1.7268872553;CRX:1.52258056396;SPI1:1.40076504014;FOX{F1,F2,J1}:1.39435095178;DMAP1_NCOR{1,2}_SMARC:1.2772753079;IRF1,2:1.22431560527;STAT5{A,B}:1.12567238121;GATA6:1.12552215;ELK1,4_GABP{A,B1}:1.09435488405;ZBTB16:1.08004808937;NANOG{mouse}:1.04612546842;SPIB:1.01051905103;BPTF:0.946937194648;PDX1:0.942583235023;YY1:0.94010229007;HMX1:0.896414344318;FOX{D1,D2}:0.883233264108;PBX1:0.876542556336;POU1F1:0.829770328509;STAT1,3:0.81413132858;ATF5_CREB3:0.800048849244;RFX2..5_RFXANK_RFXAP:0.789287566592;PAX4:0.785126889358;NFATC1..3:0.783080390988;STAT2,4,6:0.772816617673;FOXO1,3,4:0.770020640301;POU2F1..3:0.734607132369;T:0.729701892903;CREB1:0.635567720363;TGIF1:0.635327841773;NKX2-2,8:0.611663915648;MYOD1:0.576061068118;E2F1..5:0.543664876304;NFY{A,B,C}:0.524999363808;NFKB1_REL_RELA:0.508435734117;AIRE:0.493332746208;FOXN1:0.490725993686;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.480761431929;IKZF2:0.47712280311;IRF7:0.455719273869;NKX6-1,2:0.437973987629;LEF1_TCF7_TCF7L1,2:0.388716020334;NKX3-1:0.383186791724;MYB:0.38100446227;SNAI1..3:0.379617690464;ZEB1:0.371748937082;PAX2:0.322155963005;BREu{core}:0.309105834576;LMO2:0.268039619035;SPZ1:0.242455314743;HES1:0.23039306157;NFE2L1:0.216252116423;SREBF1,2:0.213792859368;JUN:0.187845835436;FOXM1:0.181061009442;TAL1_TCF{3,4,12}:0.177351849465;CUX2:0.154456010828;FOXA2:0.151226067035;EP300:0.133216019506;NRF1:0.129049656752;PITX1..3:0.0536442136333;SOX5:0.0524078154072;PAX8:0.046409354952;NFIL3:0.0379633869198;FOXP3:0.0207841078289;ZNF423:0.00961277814015;ATF4:0.00612130073545;DBP:-0.0153211481582;ATF6:-0.0337927661533;ZNF143:-0.0681035400153;OCT4_SOX2{dimer}:-0.0697146193049;FOX{I1,J2}:-0.102274248222;FOXP1:-0.104911695683;GFI1:-0.112128508695;EVI1:-0.119249062881;GLI1..3:-0.121687145126;NR5A1,2:-0.13952724023;NFIX:-0.14970323709;ZNF148:-0.155655772952;ZNF384:-0.174518456938;RXRA_VDR{dimer}:-0.185850573085;SMAD1..7,9:-0.187830049609;HOX{A6,A7,B6,B7}:-0.247293709504;HNF4A_NR2F1,2:-0.252656709102;RFX1:-0.258655259757;GCM1,2:-0.259309052902;ATF2:-0.266157369761;MYFfamily:-0.271680661269;AHR_ARNT_ARNT2:-0.278419944683;SRF:-0.285101098452;FOXQ1:-0.318913731509;ALX1:-0.334102065826;ARID5B:-0.342955148748;BACH2:-0.378243737261;NFE2L2:-0.396003890289;FOSL2:-0.397133318305;AR:-0.40495069907;NFE2:-0.407643967502;MAFB:-0.41455495091;FOS_FOS{B,L1}_JUN{B,D}:-0.416220872546;PRRX1,2:-0.421626704854;TP53:-0.428522178157;CEBPA,B_DDIT3:-0.440486337273;ESRRA:-0.444390438425;HAND1,2:-0.466940191094;HNF1A:-0.47036218338;SOX2:-0.477746705711;TFCP2:-0.477986711238;HMGA1,2:-0.487176897971;HIF1A:-0.496543468992;NHLH1,2:-0.503876711095;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.506617742994;NR3C1:-0.521898693279;RREB1:-0.525718758987;ESR1:-0.533726536869;TFDP1:-0.594219713783;VSX1,2:-0.595435341592;HSF1,2:-0.629060474131;HOXA9_MEIS1:-0.641817955165;POU5F1:-0.659915250356;POU3F1..4:-0.673710406125;HLF:-0.702289557076;FOXD3:-0.717831502643;PAX5:-0.723105610862;UFEwm:-0.745210722415;NR1H4:-0.746663230442;TFAP4:-0.747317699355;ZNF238:-0.77279581334;NANOG:-0.787450613697;REST:-0.799064160171;ONECUT1,2:-0.802182713502;NKX2-1,4:-0.819470737093;NKX2-3_NKX2-5:-0.821084364365;PPARG:-0.829862977082;PAX6:-0.852830133155;ZBTB6:-0.856945195312;ALX4:-0.863863716103;SOX{8,9,10}:-0.866023293187;MYBL2:-0.880405903724;MED-1{core}:-0.896563594838;ADNP_IRX_SIX_ZHX:-0.951141404187;SOX17:-1.01474199561;TOPORS:-1.01568081592;MZF1:-1.03979913333;PRDM1:-1.04394068884;EBF1:-1.0493697009;HBP1_HMGB_SSRP1_UBTF:-1.05473330708;NR6A1:-1.06405306395;MEF2{A,B,C,D}:-1.09521947647;MAZ:-1.09707171024;bHLH_family:-1.1432213549;HOX{A5,B5}:-1.17960672024;LHX3,4:-1.20488907723;ZFP161:-1.21088917074;GFI1B:-1.21952407596;MTE{core}:-1.24570627687;EN1,2:-1.25490292658;TBX4,5:-1.26187467348;XCPE1{core}:-1.27072391187;RBPJ:-1.28920701282;GATA4:-1.29444561378;CDC5L:-1.30755232345;TBP:-1.32054133862;KLF4:-1.32717974825;GTF2I:-1.33085310485;EGR1..3:-1.37043959213;MTF1:-1.38975388752;PATZ1:-1.39455754166;ZIC1..3:-1.39473244735;GZF1:-1.41840587863;TFAP2{A,C}:-1.51875361164;HIC1:-1.53840531412;TEF:-1.54709985557;TFAP2B:-1.58211329162;GTF2A1,2:-1.62624911048;PAX1,9:-1.63404276433;TEAD1:-1.67699438858;RXR{A,B,G}:-1.69331628058;HOX{A4,D4}:-1.73793308346;NKX3-2:-1.77860980845;TLX1..3_NFIC{dimer}:-1.78027292441;SP1:-1.839077032;IKZF1:-1.95689604558;POU6F1:-2.02298144661;XBP1:-2.02630679428;FOXL1:-2.20002231064 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11794-124C3;search_select_hide=table117:FF:11794-124C3 | |||
}} | }} |
Latest revision as of 18:20, 4 June 2020
Name: | CD4+CD25+CD45RA- memory regulatory T cells expanded, donor1 |
---|---|
Species: | Human (Homo sapiens) |
Library ID: | CNhs13204 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13204
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13204
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.131 |
10 | 10 | 0.0149 |
100 | 100 | 0.811 |
101 | 101 | 0.22 |
102 | 102 | 0.575 |
103 | 103 | 0.0787 |
104 | 104 | 0.673 |
105 | 105 | 0.14 |
106 | 106 | 0.349 |
107 | 107 | 0.399 |
108 | 108 | 0.663 |
109 | 109 | 0.0409 |
11 | 11 | 0.027 |
110 | 110 | 0.456 |
111 | 111 | 0.279 |
112 | 112 | 0.0682 |
113 | 113 | 0.575 |
114 | 114 | 0.102 |
115 | 115 | 0.341 |
116 | 116 | 0.789 |
117 | 117 | 0.00275 |
118 | 118 | 0.372 |
119 | 119 | 0.715 |
12 | 12 | 0.439 |
120 | 120 | 0.205 |
121 | 121 | 0.4 |
122 | 122 | 0.21 |
123 | 123 | 0.0118 |
124 | 124 | 0.14 |
125 | 125 | 0.783 |
126 | 126 | 0.208 |
127 | 127 | 0.362 |
128 | 128 | 0.725 |
129 | 129 | 0.329 |
13 | 13 | 0.487 |
130 | 130 | 0.88 |
131 | 131 | 0.805 |
132 | 132 | 0.821 |
133 | 133 | 0.35 |
134 | 134 | 0.843 |
135 | 135 | 0.638 |
136 | 136 | 0.591 |
137 | 137 | 0.0237 |
138 | 138 | 0.146 |
139 | 139 | 0.112 |
14 | 14 | 0.309 |
140 | 140 | 0.0705 |
141 | 141 | 0.478 |
142 | 142 | 0.941 |
143 | 143 | 2.59906e-4 |
144 | 144 | 0.419 |
145 | 145 | 0.261 |
146 | 146 | 0.58 |
147 | 147 | 0.0346 |
148 | 148 | 0.0462 |
149 | 149 | 0.804 |
15 | 15 | 0.086 |
150 | 150 | 0.452 |
151 | 151 | 0.649 |
152 | 152 | 0.717 |
153 | 153 | 0.883 |
154 | 154 | 0.789 |
155 | 155 | 0.029 |
156 | 156 | 0.608 |
157 | 157 | 0.0683 |
158 | 158 | 0.431 |
159 | 159 | 0.273 |
16 | 16 | 0.475 |
160 | 160 | 0.558 |
161 | 161 | 0.229 |
162 | 162 | 0.0848 |
163 | 163 | 0.536 |
164 | 164 | 0.145 |
165 | 165 | 0.244 |
166 | 166 | 0.659 |
167 | 167 | 0.562 |
168 | 168 | 0.258 |
169 | 169 | 0.22 |
17 | 17 | 0.826 |
18 | 18 | 0.383 |
19 | 19 | 0.779 |
2 | 2 | 0.911 |
20 | 20 | 0.742 |
21 | 21 | 0.461 |
22 | 22 | 0.965 |
23 | 23 | 0.803 |
24 | 24 | 0.729 |
25 | 25 | 0.0701 |
26 | 26 | 0.114 |
27 | 27 | 0.14 |
28 | 28 | 0.426 |
29 | 29 | 0.00715 |
3 | 3 | 0.0381 |
30 | 30 | 0.224 |
31 | 31 | 0.996 |
32 | 32 | 0.55 |
33 | 33 | 0.411 |
34 | 34 | 0.951 |
35 | 35 | 0.194 |
36 | 36 | 0.0212 |
37 | 37 | 0.129 |
38 | 38 | 0.648 |
39 | 39 | 0.409 |
4 | 4 | 0.961 |
40 | 40 | 0.293 |
41 | 41 | 0.355 |
42 | 42 | 0.0631 |
43 | 43 | 0.34 |
44 | 44 | 0.228 |
45 | 45 | 0.667 |
46 | 46 | 0.0771 |
47 | 47 | 0.00567 |
48 | 48 | 0.0393 |
49 | 49 | 0.209 |
5 | 5 | 0.448 |
50 | 50 | 0.66 |
51 | 51 | 0.527 |
52 | 52 | 0.332 |
53 | 53 | 0.468 |
54 | 54 | 0.8 |
55 | 55 | 0.73 |
56 | 56 | 0.484 |
57 | 57 | 0.43 |
58 | 58 | 0.094 |
59 | 59 | 0.171 |
6 | 6 | 0.739 |
60 | 60 | 0.385 |
61 | 61 | 0.0999 |
62 | 62 | 0.0364 |
63 | 63 | 0.645 |
64 | 64 | 0.159 |
65 | 65 | 0.816 |
66 | 66 | 0.952 |
67 | 67 | 0.71 |
68 | 68 | 0.762 |
69 | 69 | 0.798 |
7 | 7 | 0.244 |
70 | 70 | 0.0265 |
71 | 71 | 0.0191 |
72 | 72 | 0.016 |
73 | 73 | 0.359 |
74 | 74 | 0.297 |
75 | 75 | 0.0185 |
76 | 76 | 0.412 |
77 | 77 | 0.721 |
78 | 78 | 0.0492 |
79 | 79 | 0.488 |
8 | 8 | 0.544 |
80 | 80 | 0.0271 |
81 | 81 | 0.352 |
82 | 82 | 0.0548 |
83 | 83 | 0.912 |
84 | 84 | 0.264 |
85 | 85 | 0.731 |
86 | 86 | 0.13 |
87 | 87 | 0.191 |
88 | 88 | 0.683 |
89 | 89 | 0.931 |
9 | 9 | 0.586 |
90 | 90 | 0.034 |
91 | 91 | 0.562 |
92 | 92 | 0.388 |
93 | 93 | 0.29 |
94 | 94 | 0.0985 |
95 | 95 | 0.0146 |
96 | 96 | 0.0351 |
97 | 97 | 0.324 |
98 | 98 | 0.35 |
99 | 99 | 0.0399 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13204
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000002 in vivo cell sample
FF:0000210 human sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
NA