FF:10825-111C6: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005310 | ||
| | |accession_numbers=CAGE;DRX007856;DRR008728;DRZ000153;DRZ001538;DRZ011503;DRZ012888 | ||
| | |ancestors_in_anatomy_facet= | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | ||
| | |ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:1036,DOID:8692 | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0102580,FF:0101035,FF:0100740,FF:0100664 | |||
|comment= | |||
| | |created_by= | ||
|creation_date= | |||
|data_phase=2 | |||
| | |datafreeze_phase=2 | ||
| | |def= | ||
| | |expression_enrichment_score=chrX:48644984..48645005,+!p1@GATA1!2.31!202.53!GATA1;;chr17:40441354..40441410,+!p2@STAT5A!2.12!132.34!STAT5A;;chr20:56100179..56100208,-!p1@CTCFL!1.98!93.72!CTCFL;;chr12:54694758..54694805,-!p1@NFE2!1.88!89.60!NFE2;;chr17:46703687..46703740,-!p1@HOXB9!1.80!62.15!HOXB9;;chr19:12998003..12998021,-!p1@KLF1!1.72!51.56!KLF1;;chr5:134369905..134369972,-!p1@PITX1!1.71!75.68!PITX1;;chr12:54694807..54694832,-!p3@NFE2!1.70!48.62!NFE2;;chr9:135854091..135854159,+!p1@GFI1B!1.69!47.84!GFI1B;;chr6:135502501..135502546,+!p1@MYB!1.67!54.31!MYB;;chr8:37963466..37963506,+!p3@ASH2L!1.66!55.49!ASH2L;;chr12:54689532..54689551,-!p4@NFE2!1.61!40.19!NFE2;;chr12:54785074..54785122,-!p2@ZNF385A!1.59!56.86!ZNF385A;;chr12:54694653..54694672,-!p2@NFE2!1.53!32.55!NFE2;;chr4:53206..53260,+!p1@ZNF595,p1@ZNF718!1.47!258.80!ZNF595;;chr3:128212033..128212051,-!p1@GATA2!1.46!28.04!GATA2;;chr20:31350184..31350200,+!p1@DNMT3B!1.42!51.37!DNMT3B;;chr3:128206762..128206781,-!p2@GATA2!1.41!148.62!GATA2;;chr19:13213511..13213545,-!p2@LYL1!1.41!26.66!LYL1;;chr6:135502408..135502459,+!p2@MYB!1.30!21.76!MYB;;chr12:54785054..54785072,-!p4@ZNF385A!1.28!20.39!ZNF385A;;chr10:94449703..94449718,+!p1@HHEX!1.25!64.31!HHEX;;chr1:47697881..47697910,-!p4@TAL1!1.25!16.67!TAL1;;chrX:48644976..48644983,+!p2@GATA1!1.21!15.10!GATA1;;chr10:70320074..70320106,+!p1@TET1!1.20!29.61!TET1;;chr8:145701192..145701241,-!p1@FOXH1!1.20!14.90!FOXH1;;chr22:19748231..19748317,+!p1@TBX1!1.19!14.31!TBX1;;chr4:174451370..174451387,-!p1@HAND2!1.17!13.92!HAND2;;chr17:40469520..40469532,-!p12@STAT3!1.16!13.53!STAT3;;chr19:13213555..13213568,-!p5@LYL1!1.16!13.53!LYL1;;chr7:50343634..50343717,+!p2@IKZF1!1.16!13.33!IKZF1;;chr5:88178983..88179012,-!p1@MEF2C!1.15!100.78!MEF2C;;chr1:47695003..47695042,-!p2@TAL1!1.15!13.14!TAL1;;chrX:48645010..48645015,+!p3@GATA1!1.11!11.76!GATA1;;chr6:20402102..20402152,+!p1@E2F3!1.10!47.64!E2F3;;chr12:54689552..54689574,-!p6@NFE2!1.10!11.57!NFE2;;chr6:135502472..135502489,+!p3@MYB!1.09!11.18!MYB;;chr20:50159198..50159299,-!p1@NFATC2!1.07!15.69!NFATC2;;chr17:46622229..46622257,-!p6@HOXB2!1.07!12.55!HOXB2;;chr20:56100155..56100163,-!p2@CTCFL!1.07!10.78!CTCFL;;chr17:46622205..46622218,-!p3@HOXB2!1.06!12.16!HOXB2;;chr17:40469457..40469494,-!p14@STAT3!1.06!10.59!STAT3;;chr2:200323414..200323455,-!p1@SATB2!1.05!22.35!SATB2;;chr12:56415246..56415286,+!p2@IKZF4!1.05!10.20!IKZF4;;chr8:106330656..106330684,+!p1@ZFPM2!1.04!26.66!ZFPM2;;chr19:22235279..22235301,+!p1@ZNF257!1.04!19.02!ZNF257;;chr11:32457075..32457095,-!p1@WT1!1.02!9.41!WT1;;chr12:56414795..56414836,+!p4@IKZF4!1.02!9.41!IKZF4;;chr17:41623692..41623715,-!p1@ETV4!1.01!40.19!ETV4;;chr6:85473156..85473210,-!p2@TBX18!1.01!11.37!TBX18;;chr17:40441330..40441344,+!p9@STAT5A!1.00!9.02!STAT5A;;chr17:46703826..46703845,-!p3@HOXB9!1.00!9.02!HOXB9;;chr22:22863052..22863133,-!p1@ZNF280B!0.99!23.72!ZNF280B;;chr3:141747459..141747475,-!p1@TFDP2!0.97!71.37!TFDP2;;chr2:239148671..239148686,-!p1@HES6!0.96!30.59!HES6;;chr17:46655730..46655791,-!p1@HOXB4!0.96!20.98!HOXB4;;chr17:40440177..40440190,+!p6@STAT5A!0.96!8.04!STAT5A;;chr20:42295713..42295738,+!p2@MYBL2!0.95!48.23!MYBL2;;chr8:37963407..37963454,+!p2@ASH2L!0.95!24.31!ASH2L;;chr10:124895472..124895508,+!p1@HMX3!0.95!7.84!HMX3;;chr5:134369879..134369898,-!p2@PITX1!0.93!7.45!PITX1;;chr17:41277372..41277418,-!p1@BRCA1!0.91!27.06!BRCA1;;chr11:32457103..32457123,-!p3@WT1!0.90!6.86!WT1;;chr6:34204642..34204664,+!p2@HMGA1!0.89!947.96!HMGA1;;chr5:88179017..88179046,-!p2@MEF2C!0.89!28.23!MEF2C;;chr10:94449675..94449694,+!p2@HHEX!0.86!17.65!HHEX;;chr11:61520075..61520136,+!p1@C11orf9!0.86!13.72!C11orf9;;chr12:54694738..54694749,-!p5@NFE2!0.86!6.27!NFE2;;chr13:36788658..36788703,-!p2@CCDC169-SOHLH2,p2@SOHLH2!0.86!6.27!SOHLH2;;chr22:22874610..22874616,-!p1@ZNF280A!0.86!6.27!ZNF280A;;chr9:135854074..135854089,+!p2@GFI1B!0.86!6.27!GFI1B;;chr17:46682321..46682362,-!p1@HOXB6!0.85!6.08!HOXB6;;chr9:124976185..124976212,-!p4@LHX6!0.85!6.08!LHX6;;chr2:200322259..200322280,-!p5@SATB2!0.85!6.08!SATB2;;chr17:40469366..40469383,-!p17@STAT3!0.84!5.88!STAT3;;chr15:76629123..76629151,+!p1@ISL2!0.83!6.47!ISL2;;chr3:138665937..138665968,-!p1@FOXL2!0.83!5.69!FOXL2;;chr2:145277640..145277771,-!p1@ZEB2!0.82!81.76!ZEB2;;chr10:51572408..51572454,+!p3@NCOA4!0.82!35.49!NCOA4;;chr19:926001..926046,+!p1@ARID3A!0.82!20.78!ARID3A;;chr20:42295745..42295765,+!p1@MYBL2!0.81!96.46!MYBL2;;chr1:47779762..47779827,-!p1@STIL,p1@TAL1!0.80!25.88!TAL1;;chr16:68118689..68118733,+!p3@NFATC3!0.80!14.31!NFATC3;;chr3:141747441..141747452,-!p4@TFDP2!0.80!7.65!TFDP2;;chr20:62680984..62680999,-!p1@SOX18!0.80!7.25!SOX18;;chr6:20402070..20402082,+!p5@E2F3!0.80!6.27!E2F3;;chr7:148581360..148581425,-!p1@EZH2!0.79!27.45!EZH2;;chr16:68119324..68119364,+!p1@NFATC3!0.79!24.70!NFATC3;;chr11:6947720..6947812,+!p1@ZNF215!0.79!6.86!ZNF215;;chr6:34204672..34204692,+!p1@HMGA1!0.78!627.60!HMGA1;;chr7:64363638..64363667,+!p1@ZNF273!0.78!27.64!ZNF273;;chr2:200322654..200322707,-!p2@SATB2!0.78!7.65!SATB2;;chr19:52074502..52074587,+!p1@ZNF175!0.77!19.21!ZNF175;;chr17:46655704..46655718,-!p2@HOXB4!0.77!7.65!HOXB4;;chr11:47400078..47400106,-!p1@SPI1!0.77!4.90!SPI1;;chr3:138665969..138665993,-!p2@FOXL2!0.77!4.90!FOXL2;;chr8:106330696..106330719,+!p2@ZFPM2!0.76!6.27!ZFPM2;;chr3:141747950..141748004,-!p7@TFDP2!0.76!4.71!TFDP2;;chr9:135854058..135854072,+!p3@GFI1B!0.76!4.71!GFI1B;;chr10:70320041..70320065,+!p2@TET1!0.76!4.71!TET1;;chr12:56415287..56415300,+!p5@IKZF4!0.76!4.71!IKZF4;;chr7:148581327..148581347,-!p2@EZH2!0.75!17.25!EZH2;;chr2:74229812..74229867,+!p1@TET3!0.75!12.55!TET3;;chr17:41622925..41622976,-!p3@ETV4!0.75!7.25!ETV4;;chr9:127533582..127533615,-!p1@NR6A1!0.75!7.25!NR6A1;;chr17:42295777..42295816,-!p7@UBTF!0.75!5.69!UBTF;;chr4:4291861..4291913,-!p1@LYAR!0.74!116.27!LYAR;;chr14:21994337..21994442,-!p1@SALL2!0.74!13.33!SALL2;;chr11:47400045..47400060,-!p6@SPI1!0.74!4.51!SPI1;;chr3:128207349..128207386,-!p3@GATA2!0.74!4.51!GATA2;;chr19:926055..926068,+!p2@ARID3A!0.73!10.20!ARID3A;;chr19:24097706..24097731,+!p2@ZNF726!0.73!8.82!ZNF726;;chr11:19262486..19262512,-!p4@E2F8!0.72!5.49!E2F8;;chr1:43148625..43148710,+!p3@YBX1!0.71!7.84!YBX1;;chr17:41622765..41622821,-!p2@ETV4!0.71!6.67!ETV4;;chr17:79881332..79881348,-!p3@MAFG!0.71!6.27!MAFG;;chr2:200322229..200322251,-!p3@SATB2!0.71!4.12!SATB2;;chr10:51572339..51572376,+!p4@NCOA4!0.69!9.61!NCOA4;;chr8:37963511..37963523,+!p4@ASH2L!0.69!3.92!ASH2L;;chr17:46703528..46703549,-!p5@HOXB9!0.69!3.92!HOXB9;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!0.69!3.92!ZBED1;;chr19:21264991..21265026,+!p1@ZNF714!0.67!27.84!ZNF714;;chr17:17726907..17726958,-!p2@SREBF1!0.67!25.88!SREBF1;;chr22:20748434..20748455,+!p1@ZNF74!0.67!13.14!ZNF74;;chr3:168864315..168864339,-!p2@MECOM!0.67!6.47!MECOM;;chr10:60145155..60145206,+!p1@TFAM!0.66!183.12!TFAM;;chr6:134274354..134274371,+!p1@TBPL1!0.66!110.78!TBPL1;;chr16:88519669..88519726,+!p1@ZFPM1!0.66!37.45!ZFPM1;;chr5:138609782..138609826,+!p5@MATR3!0.66!26.66!MATR3;;chr19:23941680..23941704,-!p1@ZNF681!0.66!11.76!ZNF681;;chr17:40440446..40440464,+!p5@STAT5A!0.66!3.53!STAT5A;;chr19:13213465..13213478,-!p7@LYL1!0.66!3.53!LYL1;;chr8:145669791..145669834,-!p1@TONSL!0.65!11.37!TONSL;;chr22:21356378..21356422,-!p2@THAP7!0.64!34.70!THAP7;;chr13:41593425..41593480,-!p1@ELF1!0.64!25.10!ELF1;;chr16:29818160..29818188,+!p6@MAZ!0.64!18.43!MAZ;;chr6:56954867..56954882,+!p2@ZNF451!0.64!11.18!ZNF451;;chr12:51566562..51566584,-!p2@TFCP2!0.64!10.59!TFCP2;;chr2:74375058..74375069,-!p3@BOLA3!0.64!6.86!BOLA3;;chr6:28973366..28973394,-!p2@ZNF311!0.64!4.31!ZNF311;;chr7:73038839..73038862,-!p1@MLXIPL!0.64!3.33!MLXIPL;;chr9:124976154..124976177,-!p5@LHX6!0.64!3.33!LHX6;;chr9:124976328..124976372,-!p2@LHX6!0.64!3.33!LHX6;;chr4:109089095..109089144,-!p6@LEF1!0.64!3.33!LEF1;;chr17:46621146..46621180,-!p10@HOXB2!0.64!3.33!HOXB2;;chr11:32457413..32457431,-!p2@WT1!0.64!3.33!WT1;;chr12:56414851..56414871,+!p6@IKZF4!0.64!3.33!IKZF4;;chr8:28748099..28748141,+!p2@HMBOX1!0.63!11.57!HMBOX1;;chr19:21265028..21265052,+!p2@ZNF714!0.63!6.47!ZNF714;;chr16:1429627..1429662,-!p2@UNKL!0.62!10.59!UNKL;;chr13:36871902..36872023,-!p1@CCDC169-SOHLH2,p1@CCDC169,p1@SOHLH2!0.62!7.65!SOHLH2;;chr1:23857698..23857733,-!p1@E2F2!0.62!6.47!E2F2;;chr16:88519743..88519754,+!p2@ZFPM1!0.62!3.53!ZFPM1;;chr12:54393880..54393962,+!p1@HOXC9!0.62!3.14!HOXC9;;chr22:21356016..21356105,-!p1@THAP7!0.61!58.43!THAP7;;chr1:151032860..151032918,+!p1@MLLT11!0.61!44.11!MLLT11;;chr19:24097675..24097699,+!p1@ZNF726!0.61!11.96!ZNF726;;chr17:46622114..46622138,-!p4@HOXB2!0.61!5.10!HOXB2;;chr17:46622440..46622477,-!p5@HOXB2!0.61!3.53!HOXB2;;chr6:126102254..126102289,+!p5@NCOA7!0.60!9.61!NCOA7;;chr19:12203100..12203132,+!p1@ZNF788!0.60!6.86!ZNF788;;chr1:247171347..247171366,-!p2@ZNF695!0.60!6.08!ZNF695;;chr17:41623009..41623053,-!p4@ETV4!0.60!5.29!ETV4;;chr18:55102598..55102623,+!p1@ONECUT2!0.60!2.94!ONECUT2;;chr4:109089901..109089930,-!p3@LEF1!0.60!2.94!LEF1;;chr11:47399996..47400014,-!p4@SPI1!0.60!2.94!SPI1;;chr7:50348268..50348366,+!p4@IKZF1!0.60!2.94!IKZF1;;chr2:178257401..178257432,-!p4@NFE2L2!0.59!19.41!NFE2L2;;chr6:12008986..12009016,+!p3@HIVEP1!0.59!10.59!HIVEP1;;chr12:3068466..3068495,+!p3@TEAD4!0.59!7.06!TEAD4;;chr1:203764633..203764674,+!p2@ZC3H11A!0.59!5.10!ZC3H11A;;chr17:42295897..42295953,-!p10@UBTF!0.59!4.12!UBTF;;chr4:4291837..4291859,-!p2@LYAR!0.58!10.78!LYAR;;chr1:249153232..249153251,-!p2@ZNF692!0.58!7.45!ZNF692;;chr17:46687959..46688007,-!p2@HOXB7!0.58!4.12!HOXB7;;chr6:28973090..28973094,-!p1@ZNF311!0.58!3.73!ZNF311;;chr1:78444778..78444800,-!p2@FUBP1!0.57!59.01!FUBP1;;chr1:8877692..8877732,-!p1@RERE!0.57!27.25!RERE;;chr14:55493763..55493824,-!p1@WDHD1!0.57!25.10!WDHD1;;chr19:925727..925784,+!p3@ARID3A!0.57!6.67!ARID3A;;chr15:76629097..76629120,+!p2@ISL2!0.57!3.14!ISL2;;chr10:124895548..124895570,+!p2@HMX3!0.57!2.74!HMX3;;chr13:100623375..100623425,-!p1@ZIC5!0.57!2.74!ZIC5;;chr2:63277948..63277974,+!p1@OTX1!0.57!2.74!OTX1;;chr19:50832895..50832928,+!p3@NR1H2!0.57!2.74!NR1H2;;chr7:102985160..102985273,-!p1@DNAJ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| ||
| | |ffid_belonging_in_development=CL:0000049,CL:0000134 | ||
| | |||
| | |||
| | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/chronic%2520myelogenous%2520leukemia%2520cell%2520line%253aK562%2520ENCODE%252c%2520biol_rep2.CNhs12335.10825-111C6.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/chronic%2520myelogenous%2520leukemia%2520cell%2520line%253aK562%2520ENCODE%252c%2520biol_rep2.CNhs12335.10825-111C6.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/chronic%2520myelogenous%2520leukemia%2520cell%2520line%253aK562%2520ENCODE%252c%2520biol_rep2.CNhs12335.10825-111C6.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/chronic%2520myelogenous%2520leukemia%2520cell%2520line%253aK562%2520ENCODE%252c%2520biol_rep2.CNhs12335.10825-111C6.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/chronic%2520myelogenous%2520leukemia%2520cell%2520line%253aK562%2520ENCODE%252c%2520biol_rep2.CNhs12335.10825-111C6.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10825-111C6 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0100664 | |||
|is_obsolete= | |||
|library_id=CNhs12335 | |||
|library_id_phase_based=2:CNhs12335 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10825 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10825 | |||
|name=chronic myelogenous leukemia cell line:K562 ENCODE, biol_rep2 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs12335,LSID913,release011,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,-0.0825641434112966,0.200901801690015,-0.199608245518425,0.405366558507592,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.153323010348428,0,0,0,0,0,0.198775870167711,0,0,0.3924446347484,0,0,0,0,0,0,0,0,0,0,0,0,-0.279077117528602,0.0295318114360353,0,0,0,0,0,0,0,0.0476241059275515,0,0,0,0,0,-0.0714782699814549,0.0777538866750895,0.10390944044741,0,0,-0.0195897405380075,0,0,0,0,0,0,0,0,0.0777538866750895,0,0,0,0,0.0777538866750895,0,0,0,-0.0755328578376348,0,0,0,0,0,-0.0466184135199583,-0.172294741985321,0.168866884807121,0,0,-0.0584468268118252,-0.0235999906566088,0,0,0,0,-0.0202814645626169,0.208742531805298,0,0,0,0,0,0,0,0,0,0,0.337733769614242,0,0,0,0,0,0,0.0519932892954235,0.251455738841334,0,0,-0.119759304760105,-0.332902686886953,0,0,0.0416150688156745,0,0,0.0388769433375448 | |||
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| |||
|rna_box=111 | |||
|rna_catalog_number= | |||
|rna_concentration=1.58391 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.17 | |||
|rna_od260/280=2.06 | |||
|rna_position=C6 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=111C6 | |||
|rna_weight_ug=79.1955 | |||
|sample_age=53 | |||
|sample_category=cell lines | |||
|sample_cell_catalog= | |||
|sample_cell_line=K562 | |||
|sample_cell_lot= | |||
|sample_cell_type=granulocyte | |||
|sample_collaboration=Carrie Davis (Cold spring Harbor Laboratories) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.87582324782032e-310!GO:0043227;membrane-bound organelle;3.90221813854266e-261!GO:0043226;organelle;3.90221813854266e-261!GO:0043231;intracellular membrane-bound organelle;5.62771297042322e-261!GO:0043229;intracellular organelle;1.4370391210929e-260!GO:0044422;organelle part;1.64108484679636e-186!GO:0044446;intracellular organelle part;3.77320176928398e-185!GO:0005737;cytoplasm;9.70546784826009e-176!GO:0044237;cellular metabolic process;4.64991837490457e-135!GO:0005634;nucleus;2.56708159032322e-133!GO:0044238;primary metabolic process;9.02096421415525e-129!GO:0044444;cytoplasmic part;3.08673022549173e-128!GO:0032991;macromolecular complex;3.12949047880681e-124!GO:0043170;macromolecule metabolic process;3.6961214622691e-120!GO:0044428;nuclear part;2.50044534084293e-105!GO:0030529;ribonucleoprotein complex;4.43333724196957e-103!GO:0043233;organelle lumen;1.43714969720996e-102!GO:0031974;membrane-enclosed lumen;1.43714969720996e-102!GO:0003723;RNA binding;9.97415828241042e-94!GO:0005739;mitochondrion;8.46654514809171e-86!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.22695278131072e-75!GO:0043283;biopolymer metabolic process;7.24755007194025e-75!GO:0010467;gene expression;2.04871163344241e-70!GO:0006396;RNA processing;1.21248265941784e-68!GO:0031981;nuclear lumen;1.4503070714304e-64!GO:0043234;protein complex;1.23146996542284e-62!GO:0006412;translation;4.94211314666026e-62!GO:0044429;mitochondrial part;7.39722784885898e-60!GO:0005840;ribosome;9.50212650218067e-59!GO:0005515;protein binding;3.3388492770326e-57!GO:0006259;DNA metabolic process;7.68809642326849e-57!GO:0031967;organelle envelope;7.79778228534387e-55!GO:0031975;envelope;2.10734019844923e-54!GO:0003676;nucleic acid binding;1.28566794464511e-53!GO:0009058;biosynthetic process;1.4910277339023e-52!GO:0016071;mRNA metabolic process;7.14038420964963e-52!GO:0003735;structural constituent of ribosome;3.37270355043203e-51!GO:0031090;organelle membrane;9.53979647569342e-51!GO:0044249;cellular biosynthetic process;2.25130956892961e-50!GO:0019538;protein metabolic process;8.44751818136935e-50!GO:0009059;macromolecule biosynthetic process;5.18995744694244e-48!GO:0008380;RNA splicing;1.29666701930862e-46!GO:0006397;mRNA processing;2.32224620528927e-46!GO:0043228;non-membrane-bound organelle;4.3047463415358e-45!GO:0043232;intracellular non-membrane-bound organelle;4.3047463415358e-45!GO:0044267;cellular protein metabolic process;9.33420031549792e-45!GO:0044260;cellular macromolecule metabolic process;6.83180253437919e-44!GO:0033279;ribosomal subunit;8.61691622857326e-44!GO:0016043;cellular component organization and biogenesis;8.01231749795352e-43!GO:0006996;organelle organization and biogenesis;2.47516252415375e-42!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.43509359695906e-41!GO:0033036;macromolecule localization;1.86363616320065e-40!GO:0005654;nucleoplasm;1.22296975962535e-39!GO:0065003;macromolecular complex assembly;2.55347825673826e-39!GO:0005829;cytosol;2.99066916157324e-39!GO:0015031;protein transport;3.48774165602004e-39!GO:0005740;mitochondrial envelope;1.27021340771865e-37!GO:0016070;RNA metabolic process;1.59475860955768e-37!GO:0007049;cell cycle;1.019474499628e-36!GO:0019866;organelle inner membrane;2.29805420963682e-36!GO:0045184;establishment of protein localization;7.8420016130347e-36!GO:0008104;protein localization;9.11182206027036e-36!GO:0031966;mitochondrial membrane;1.40700272611722e-34!GO:0022607;cellular component assembly;2.12284813355063e-34!GO:0046907;intracellular transport;2.75048327128928e-34!GO:0000166;nucleotide binding;4.70421906049642e-34!GO:0005681;spliceosome;6.9544743135967e-34!GO:0005743;mitochondrial inner membrane;1.86285319507599e-33!GO:0006974;response to DNA damage stimulus;2.1844241081434e-31!GO:0044451;nucleoplasm part;8.72142500008092e-31!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.98992643531571e-30!GO:0044445;cytosolic part;6.13559951559539e-30!GO:0006281;DNA repair;1.80554123416777e-29!GO:0006886;intracellular protein transport;2.68961267215198e-28!GO:0000278;mitotic cell cycle;4.49969880304076e-28!GO:0005694;chromosome;6.7650120123726e-28!GO:0022402;cell cycle process;2.42566832553833e-27!GO:0031980;mitochondrial lumen;4.20348194830197e-27!GO:0005759;mitochondrial matrix;4.20348194830197e-27!GO:0016462;pyrophosphatase activity;2.53035726312219e-26!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.10346157555859e-26!GO:0017111;nucleoside-triphosphatase activity;4.13124819904927e-26!GO:0016817;hydrolase activity, acting on acid anhydrides;4.57836739972333e-26!GO:0051276;chromosome organization and biogenesis;8.45595561575064e-26!GO:0005730;nucleolus;1.19832533105643e-25!GO:0044455;mitochondrial membrane part;1.37418000926927e-25!GO:0006260;DNA replication;4.78427091675697e-25!GO:0006119;oxidative phosphorylation;3.77479830314516e-24!GO:0044427;chromosomal part;7.23687194313619e-24!GO:0051649;establishment of cellular localization;7.4924847770998e-24!GO:0016874;ligase activity;7.55857552444849e-24!GO:0022403;cell cycle phase;9.66983214296536e-24!GO:0015934;large ribosomal subunit;3.94680625954955e-23!GO:0032553;ribonucleotide binding;4.79452474694753e-23!GO:0032555;purine ribonucleotide binding;4.79452474694753e-23!GO:0051641;cellular localization;4.89223252944842e-23!GO:0000087;M phase of mitotic cell cycle;7.90012483212399e-23!GO:0017076;purine nucleotide binding;1.23945708173454e-22!GO:0007067;mitosis;2.4831667805331e-22!GO:0005524;ATP binding;4.36373405464949e-22!GO:0032559;adenyl ribonucleotide binding;5.17960153861032e-22!GO:0015935;small ribosomal subunit;9.44528570206413e-22!GO:0022618;protein-RNA complex assembly;9.59639396818783e-22!GO:0006457;protein folding;1.21931705571954e-21!GO:0051301;cell division;1.93608992567984e-21!GO:0009719;response to endogenous stimulus;2.44979821789484e-21!GO:0030554;adenyl nucleotide binding;2.60355678709705e-21!GO:0006512;ubiquitin cycle;5.10156695741947e-21!GO:0042254;ribosome biogenesis and assembly;1.17675612541622e-20!GO:0000279;M phase;1.63321241455804e-20!GO:0044265;cellular macromolecule catabolic process;4.321127180832e-20!GO:0016887;ATPase activity;8.91111089538428e-20!GO:0012505;endomembrane system;2.85450351082508e-19!GO:0006325;establishment and/or maintenance of chromatin architecture;3.72935272081699e-19!GO:0042623;ATPase activity, coupled;1.1052304609175e-18!GO:0051186;cofactor metabolic process;1.67041987335043e-18!GO:0006323;DNA packaging;1.69234238614522e-18!GO:0005746;mitochondrial respiratory chain;2.03934420201937e-18!GO:0008135;translation factor activity, nucleic acid binding;2.09619420633359e-18!GO:0005635;nuclear envelope;4.17001469368632e-18!GO:0044453;nuclear membrane part;7.5845440982976e-18!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;8.68972448745312e-18!GO:0005761;mitochondrial ribosome;1.05399209933425e-17!GO:0000313;organellar ribosome;1.05399209933425e-17!GO:0009057;macromolecule catabolic process;1.18469746196799e-17!GO:0006399;tRNA metabolic process;3.37204961859933e-17!GO:0043285;biopolymer catabolic process;5.3720999956579e-17!GO:0000398;nuclear mRNA splicing, via spliceosome;6.70544026731534e-17!GO:0000375;RNA splicing, via transesterification reactions;6.70544026731534e-17!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;6.70544026731534e-17!GO:0050136;NADH dehydrogenase (quinone) activity;9.4583875881375e-17!GO:0003954;NADH dehydrogenase activity;9.4583875881375e-17!GO:0008137;NADH dehydrogenase (ubiquinone) activity;9.4583875881375e-17!GO:0031965;nuclear membrane;9.47913874001801e-17!GO:0044248;cellular catabolic process;2.33877473849222e-16!GO:0006511;ubiquitin-dependent protein catabolic process;2.8346660767914e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;2.98671069023683e-16!GO:0019941;modification-dependent protein catabolic process;3.27652340009638e-16!GO:0043632;modification-dependent macromolecule catabolic process;3.27652340009638e-16!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);4.49195651661943e-16!GO:0044257;cellular protein catabolic process;6.5418372422648e-16!GO:0016604;nuclear body;8.26989498544924e-16!GO:0005643;nuclear pore;9.55575873599878e-16!GO:0006605;protein targeting;1.06301396373701e-15!GO:0004386;helicase activity;1.2826593591461e-15!GO:0000502;proteasome complex (sensu Eukaryota);1.56463597738065e-15!GO:0051082;unfolded protein binding;2.41995230227967e-15!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;3.09972286712626e-15!GO:0042775;organelle ATP synthesis coupled electron transport;4.74812479626071e-15!GO:0042773;ATP synthesis coupled electron transport;4.74812479626071e-15!GO:0030964;NADH dehydrogenase complex (quinone);7.00183056878648e-15!GO:0045271;respiratory chain complex I;7.00183056878648e-15!GO:0005747;mitochondrial respiratory chain complex I;7.00183056878648e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);7.27961525203365e-15!GO:0050657;nucleic acid transport;1.37898777962146e-14!GO:0051236;establishment of RNA localization;1.37898777962146e-14!GO:0050658;RNA transport;1.37898777962146e-14!GO:0008134;transcription factor binding;1.63020040649009e-14!GO:0006403;RNA localization;1.67688340162156e-14!GO:0006732;coenzyme metabolic process;1.95407906800042e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.21687225130199e-14!GO:0003743;translation initiation factor activity;3.2875590384777e-14!GO:0048770;pigment granule;3.34934732698479e-14!GO:0042470;melanosome;3.34934732698479e-14!GO:0065002;intracellular protein transport across a membrane;1.04512871300459e-13!GO:0016568;chromatin modification;1.50651462793434e-13!GO:0006364;rRNA processing;1.52339120719644e-13!GO:0008026;ATP-dependent helicase activity;1.92358822476114e-13!GO:0046930;pore complex;2.15950770379692e-13!GO:0006261;DNA-dependent DNA replication;2.70415735866348e-13!GO:0016072;rRNA metabolic process;2.71390240826344e-13!GO:0030163;protein catabolic process;3.23249798564876e-13!GO:0006413;translational initiation;3.48910573123383e-13!GO:0043412;biopolymer modification;9.86777885014528e-13!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.02897945129125e-12!GO:0004812;aminoacyl-tRNA ligase activity;1.02897945129125e-12!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.02897945129125e-12!GO:0051028;mRNA transport;1.27526060062168e-12!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.35844749524995e-12!GO:0006913;nucleocytoplasmic transport;1.96697496309162e-12!GO:0043038;amino acid activation;2.36301483272335e-12!GO:0006418;tRNA aminoacylation for protein translation;2.36301483272335e-12!GO:0043039;tRNA aminoacylation;2.36301483272335e-12!GO:0065004;protein-DNA complex assembly;2.96922493296988e-12!GO:0051188;cofactor biosynthetic process;3.79133990592282e-12!GO:0016607;nuclear speck;4.38784562234469e-12!GO:0051169;nuclear transport;4.45703951166818e-12!GO:0048193;Golgi vesicle transport;4.92478399314662e-12!GO:0005783;endoplasmic reticulum;5.01239408290191e-12!GO:0006333;chromatin assembly or disassembly;5.01239408290191e-12!GO:0044432;endoplasmic reticulum part;8.03829725608374e-12!GO:0000775;chromosome, pericentric region;1.00189430689236e-11!GO:0006163;purine nucleotide metabolic process;1.09725940458013e-11!GO:0015630;microtubule cytoskeleton;1.19618378782534e-11!GO:0009259;ribonucleotide metabolic process;1.20278682225921e-11!GO:0003712;transcription cofactor activity;1.49628711857118e-11!GO:0006446;regulation of translational initiation;1.60415427538597e-11!GO:0000074;regulation of progression through cell cycle;3.49194984519666e-11!GO:0009055;electron carrier activity;3.5273329364216e-11!GO:0051726;regulation of cell cycle;3.71655704737793e-11!GO:0016779;nucleotidyltransferase activity;6.37054057677226e-11!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;9.26016568063322e-11!GO:0006164;purine nucleotide biosynthetic process;9.43416165112804e-11!GO:0016740;transferase activity;1.08944095998028e-10!GO:0008565;protein transporter activity;1.16457588020262e-10!GO:0000785;chromatin;1.21779923004618e-10!GO:0006461;protein complex assembly;1.33267689828736e-10!GO:0009150;purine ribonucleotide metabolic process;1.80587174272493e-10!GO:0009260;ribonucleotide biosynthetic process;2.32427873504014e-10!GO:0003697;single-stranded DNA binding;2.40678383236014e-10!GO:0006464;protein modification process;2.60352303728487e-10!GO:0006366;transcription from RNA polymerase II promoter;2.82328062447979e-10!GO:0019222;regulation of metabolic process;4.2112993322328e-10!GO:0017038;protein import;5.54072965120668e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;7.85495053999049e-10!GO:0009152;purine ribonucleotide biosynthetic process;1.58314649223447e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.58755307048895e-09!GO:0009056;catabolic process;1.89477906635662e-09!GO:0043566;structure-specific DNA binding;1.94184683741088e-09!GO:0007005;mitochondrion organization and biogenesis;2.39962362155005e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.55592612240197e-09!GO:0043687;post-translational protein modification;2.58690451128732e-09!GO:0009108;coenzyme biosynthetic process;3.15871463153984e-09!GO:0009141;nucleoside triphosphate metabolic process;5.02229656883331e-09!GO:0030532;small nuclear ribonucleoprotein complex;5.26823942945258e-09!GO:0008094;DNA-dependent ATPase activity;5.63854460819746e-09!GO:0008639;small protein conjugating enzyme activity;6.00488362379852e-09!GO:0005813;centrosome;6.9019411240594e-09!GO:0009199;ribonucleoside triphosphate metabolic process;7.77926235439747e-09!GO:0005794;Golgi apparatus;8.60940638544183e-09!GO:0016192;vesicle-mediated transport;8.89920378543903e-09!GO:0005819;spindle;1.03580890310922e-08!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.08026319934264e-08!GO:0003899;DNA-directed RNA polymerase activity;1.65130882540121e-08!GO:0012501;programmed cell death;1.67236672416728e-08!GO:0015986;ATP synthesis coupled proton transport;1.70275486268842e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.70275486268842e-08!GO:0004842;ubiquitin-protein ligase activity;1.77447467691863e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.83567774643284e-08!GO:0009144;purine nucleoside triphosphate metabolic process;1.83567774643284e-08!GO:0005789;endoplasmic reticulum membrane;1.98606472196054e-08!GO:0006915;apoptosis;2.30378409773417e-08!GO:0005815;microtubule organizing center;2.35606723611593e-08!GO:0009142;nucleoside triphosphate biosynthetic process;2.72429490985407e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.72429490985407e-08!GO:0019787;small conjugating protein ligase activity;2.92267469377093e-08!GO:0031323;regulation of cellular metabolic process;4.67321944898983e-08!GO:0046034;ATP metabolic process;4.70780618561128e-08!GO:0016741;transferase activity, transferring one-carbon groups;4.96928211987257e-08!GO:0009060;aerobic respiration;5.06172873054383e-08!GO:0008168;methyltransferase activity;5.82094498350046e-08!GO:0000245;spliceosome assembly;6.03891988560346e-08!GO:0000075;cell cycle checkpoint;6.57958423432096e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;6.68183604785229e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;6.68183604785229e-08!GO:0006334;nucleosome assembly;6.77736560011369e-08!GO:0031497;chromatin assembly;6.90377277775816e-08!GO:0019829;cation-transporting ATPase activity;7.49314514676458e-08!GO:0051329;interphase of mitotic cell cycle;7.59851443958577e-08!GO:0016787;hydrolase activity;7.85643184848871e-08!GO:0008219;cell death;8.26342099431954e-08!GO:0016265;death;8.26342099431954e-08!GO:0006350;transcription;1.03031173411036e-07!GO:0005657;replication fork;1.03187909108072e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.05048216406577e-07!GO:0015078;hydrogen ion transmembrane transporter activity;1.05048216406577e-07!GO:0006754;ATP biosynthetic process;1.29958406010092e-07!GO:0006753;nucleoside phosphate metabolic process;1.29958406010092e-07!GO:0006752;group transfer coenzyme metabolic process;1.35760138905853e-07!GO:0051325;interphase;1.59071629099944e-07!GO:0016881;acid-amino acid ligase activity;2.68224623518368e-07!GO:0050794;regulation of cellular process;2.71541561444168e-07!GO:0005667;transcription factor complex;2.79633951070277e-07!GO:0045333;cellular respiration;3.39954764249749e-07!GO:0045259;proton-transporting ATP synthase complex;3.67683852757685e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;4.18911679306813e-07!GO:0016469;proton-transporting two-sector ATPase complex;4.87964630284174e-07!GO:0006084;acetyl-CoA metabolic process;7.66626747802461e-07!GO:0003724;RNA helicase activity;9.0823631225053e-07!GO:0006099;tricarboxylic acid cycle;9.33576476014364e-07!GO:0046356;acetyl-CoA catabolic process;9.33576476014364e-07!GO:0051246;regulation of protein metabolic process;9.36740020872209e-07!GO:0006888;ER to Golgi vesicle-mediated transport;9.89086904749064e-07!GO:0006302;double-strand break repair;1.03500842551194e-06!GO:0043623;cellular protein complex assembly;1.04651361416074e-06!GO:0051170;nuclear import;1.05418147904062e-06!GO:0005768;endosome;1.31570419741894e-06!GO:0009117;nucleotide metabolic process;1.3394309597865e-06!GO:0008033;tRNA processing;1.51353816233961e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.90183850573295e-06!GO:0000151;ubiquitin ligase complex;2.12795510674879e-06!GO:0003677;DNA binding;2.19481931862557e-06!GO:0010468;regulation of gene expression;2.24963077730241e-06!GO:0003684;damaged DNA binding;2.39085450305556e-06!GO:0048475;coated membrane;2.52944764367995e-06!GO:0030117;membrane coat;2.52944764367995e-06!GO:0016853;isomerase activity;2.54944726234324e-06!GO:0006606;protein import into nucleus;2.79507796241074e-06!GO:0000776;kinetochore;2.89955054597855e-06!GO:0005762;mitochondrial large ribosomal subunit;2.92635885871003e-06!GO:0000315;organellar large ribosomal subunit;2.92635885871003e-06!GO:0006310;DNA recombination;2.95974758234911e-06!GO:0032446;protein modification by small protein conjugation;3.11910840178084e-06!GO:0016563;transcription activator activity;4.19243191221544e-06!GO:0044452;nucleolar part;4.33867106418337e-06!GO:0005793;ER-Golgi intermediate compartment;4.3744254038289e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;4.48864085078697e-06!GO:0003713;transcription coactivator activity;4.52392196422662e-06!GO:0007051;spindle organization and biogenesis;4.52923112342982e-06!GO:0009109;coenzyme catabolic process;5.0740096107082e-06!GO:0016491;oxidoreductase activity;5.1516029848052e-06!GO:0006352;transcription initiation;5.32635730517387e-06!GO:0004527;exonuclease activity;6.30226617488681e-06!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;6.74238227018516e-06!GO:0016567;protein ubiquitination;7.02288269372855e-06!GO:0006839;mitochondrial transport;7.28489031729763e-06!GO:0003682;chromatin binding;7.41440234908492e-06!GO:0032774;RNA biosynthetic process;8.35568986975072e-06!GO:0000314;organellar small ribosomal subunit;8.79439177936366e-06!GO:0005763;mitochondrial small ribosomal subunit;8.79439177936366e-06!GO:0016363;nuclear matrix;8.81073954569366e-06!GO:0003678;DNA helicase activity;8.81073954569366e-06!GO:0008654;phospholipid biosynthetic process;9.17677849070967e-06!GO:0007059;chromosome segregation;9.26598099139485e-06!GO:0051187;cofactor catabolic process;1.1552699093421e-05!GO:0006351;transcription, DNA-dependent;1.16790616272299e-05!GO:0051168;nuclear export;1.23625571342227e-05!GO:0051052;regulation of DNA metabolic process;1.4450493920287e-05!GO:0042981;regulation of apoptosis;1.60736370245233e-05!GO:0030120;vesicle coat;1.60736370245233e-05!GO:0030662;coated vesicle membrane;1.60736370245233e-05!GO:0006613;cotranslational protein targeting to membrane;1.65749914334496e-05!GO:0043067;regulation of programmed cell death;1.67452802961321e-05!GO:0006383;transcription from RNA polymerase III promoter;1.78915341216559e-05!GO:0004518;nuclease activity;1.88791320610649e-05!GO:0005839;proteasome core complex (sensu Eukaryota);1.94648457540718e-05!GO:0043021;ribonucleoprotein binding;2.09644048624634e-05!GO:0032508;DNA duplex unwinding;2.25592154875272e-05!GO:0032392;DNA geometric change;2.25592154875272e-05!GO:0006414;translational elongation;2.28153185881472e-05!GO:0006626;protein targeting to mitochondrion;2.41275896573329e-05!GO:0051427;hormone receptor binding;2.62026522113151e-05!GO:0006091;generation of precursor metabolites and energy;2.76613285076372e-05!GO:0016310;phosphorylation;2.76695244390462e-05!GO:0007093;mitotic cell cycle checkpoint;3.1533774720669e-05!GO:0019752;carboxylic acid metabolic process;3.16602283472581e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;3.19519605451324e-05!GO:0015399;primary active transmembrane transporter activity;3.19519605451324e-05!GO:0006082;organic acid metabolic process;3.6980609015186e-05!GO:0003714;transcription corepressor activity;3.75975683792973e-05!GO:0044440;endosomal part;3.88665646586625e-05!GO:0010008;endosome membrane;3.88665646586625e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;4.13220623151433e-05!GO:0030880;RNA polymerase complex;4.47748559145688e-05!GO:0006268;DNA unwinding during replication;5.11205852972644e-05!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;5.49654187187074e-05!GO:0035257;nuclear hormone receptor binding;5.75575942972548e-05!GO:0005798;Golgi-associated vesicle;5.77117619530852e-05!GO:0005788;endoplasmic reticulum lumen;6.20803504375514e-05!GO:0006793;phosphorus metabolic process;6.49835778866389e-05!GO:0006796;phosphate metabolic process;6.49835778866389e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;6.65409944280412e-05!GO:0000049;tRNA binding;6.66850089417216e-05!GO:0004298;threonine endopeptidase activity;6.95669259444023e-05!GO:0006520;amino acid metabolic process;7.06906519764224e-05!GO:0022890;inorganic cation transmembrane transporter activity;7.5323272330553e-05!GO:0044431;Golgi apparatus part;7.56692053615349e-05!GO:0008186;RNA-dependent ATPase activity;8.22567296575351e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;8.43425073016484e-05!GO:0006338;chromatin remodeling;8.44339281840597e-05!GO:0005874;microtubule;8.81888862703183e-05!GO:0006401;RNA catabolic process;9.13731373520224e-05!GO:0005758;mitochondrial intermembrane space;9.31340348140648e-05!GO:0006270;DNA replication initiation;9.62299675327725e-05!GO:0016859;cis-trans isomerase activity;0.000102641156665712!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00011397074200075!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000115158814317306!GO:0000428;DNA-directed RNA polymerase complex;0.000115158814317306!GO:0007088;regulation of mitosis;0.000115158814317306!GO:0043681;protein import into mitochondrion;0.000117208541988018!GO:0016564;transcription repressor activity;0.000119673647368154!GO:0009165;nucleotide biosynthetic process;0.000119673647368154!GO:0006402;mRNA catabolic process;0.000121323231144639!GO:0003690;double-stranded DNA binding;0.00012201005022051!GO:0003729;mRNA binding;0.000129776974236165!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000130748488664418!GO:0003924;GTPase activity;0.000133928303054188!GO:0046483;heterocycle metabolic process;0.000139002206083252!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000146529096990684!GO:0000059;protein import into nucleus, docking;0.000152416081688092!GO:0031072;heat shock protein binding;0.0001706706181716!GO:0005770;late endosome;0.000173221009890233!GO:0050789;regulation of biological process;0.000177086818702636!GO:0045449;regulation of transcription;0.000183598452023256!GO:0031970;organelle envelope lumen;0.000184442017558164!GO:0031988;membrane-bound vesicle;0.000186600997052474!GO:0007017;microtubule-based process;0.000186606455151015!GO:0015631;tubulin binding;0.000228351127663696!GO:0004004;ATP-dependent RNA helicase activity;0.000240315960361295!GO:0007052;mitotic spindle organization and biogenesis;0.000266780159747399!GO:0046467;membrane lipid biosynthetic process;0.00031976036244489!GO:0045454;cell redox homeostasis;0.000343031630908415!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000345246057514984!GO:0046474;glycerophospholipid biosynthetic process;0.000366872359732183!GO:0016023;cytoplasmic membrane-bound vesicle;0.000383740676203098!GO:0031968;organelle outer membrane;0.000385873931780676!GO:0006007;glucose catabolic process;0.000434732818507756!GO:0019867;outer membrane;0.000454240555818849!GO:0005684;U2-dependent spliceosome;0.000459384300395431!GO:0015992;proton transport;0.000486998382177731!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000490924409703858!GO:0006612;protein targeting to membrane;0.000511895751552928!GO:0046489;phosphoinositide biosynthetic process;0.000511895751552928!GO:0000922;spindle pole;0.000512070737534851!GO:0043492;ATPase activity, coupled to movement of substances;0.000513805166035093!GO:0003711;transcription elongation regulator activity;0.000514325643167156!GO:0006284;base-excision repair;0.000532590683303144!GO:0005669;transcription factor TFIID complex;0.00054149264066556!GO:0007006;mitochondrial membrane organization and biogenesis;0.00054165512475494!GO:0008610;lipid biosynthetic process;0.000560076794112135!GO:0005637;nuclear inner membrane;0.000565310302465309!GO:0006818;hydrogen transport;0.000581317459663537!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000582008936371785!GO:0005741;mitochondrial outer membrane;0.000586405638016034!GO:0016251;general RNA polymerase II transcription factor activity;0.000589913754567849!GO:0031324;negative regulation of cellular metabolic process;0.000676530272938105!GO:0032200;telomere organization and biogenesis;0.000677689902792796!GO:0000723;telomere maintenance;0.000677689902792796!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000683951051967144!GO:0000139;Golgi membrane;0.000697922442722305!GO:0043069;negative regulation of programmed cell death;0.000732102393247298!GO:0008276;protein methyltransferase activity;0.000740682871485085!GO:0009451;RNA modification;0.000743367117360101!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000749849315512377!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000749849315512377!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000749849315512377!GO:0006519;amino acid and derivative metabolic process;0.000759067305125928!GO:0009892;negative regulation of metabolic process;0.000782029672513346!GO:0030867;rough endoplasmic reticulum membrane;0.000804263363390541!GO:0000786;nucleosome;0.000818211628510319!GO:0043284;biopolymer biosynthetic process;0.000818211628510319!GO:0051252;regulation of RNA metabolic process;0.000828770472517525!GO:0019899;enzyme binding;0.000829095895217136!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000880894515973473!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000891985686037398!GO:0006275;regulation of DNA replication;0.000891985686037398!GO:0006405;RNA export from nucleus;0.000907055313919718!GO:0051920;peroxiredoxin activity;0.0009343149522382!GO:0043066;negative regulation of apoptosis;0.00096603187351111!GO:0006916;anti-apoptosis;0.00101260786020588!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00101474184369536!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00101474184369536!GO:0000096;sulfur amino acid metabolic process;0.00103084062846711!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00103896716326921!GO:0008250;oligosaccharyl transferase complex;0.00104777956894644!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00106406040901815!GO:0006144;purine base metabolic process;0.00107646832372735!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00108888975046088!GO:0005885;Arp2/3 protein complex;0.00113231108969521!GO:0000819;sister chromatid segregation;0.00114823938615107!GO:0005048;signal sequence binding;0.00118806497607236!GO:0051539;4 iron, 4 sulfur cluster binding;0.00125553595740839!GO:0004576;oligosaccharyl transferase activity;0.00131587983731077!GO:0050662;coenzyme binding;0.0013383345568612!GO:0006355;regulation of transcription, DNA-dependent;0.00133966755475811!GO:0048500;signal recognition particle;0.00135875942455883!GO:0031982;vesicle;0.00146118151907446!GO:0000725;recombinational repair;0.00148426074590149!GO:0000724;double-strand break repair via homologous recombination;0.00148426074590149!GO:0030384;phosphoinositide metabolic process;0.00148812775902453!GO:0043596;nuclear replication fork;0.00150379842505976!GO:0051087;chaperone binding;0.00150570767878081!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00154477215775127!GO:0005525;GTP binding;0.00157898031819251!GO:0000070;mitotic sister chromatid segregation;0.00167394065256521!GO:0006891;intra-Golgi vesicle-mediated transport;0.00171221592106351!GO:0004003;ATP-dependent DNA helicase activity;0.00171460261309365!GO:0005791;rough endoplasmic reticulum;0.00172007979958375!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00174091064575671!GO:0005769;early endosome;0.00179489314207157!GO:0031124;mRNA 3'-end processing;0.00184568461136359!GO:0006779;porphyrin biosynthetic process;0.00184568461136359!GO:0033014;tetrapyrrole biosynthetic process;0.00184568461136359!GO:0048471;perinuclear region of cytoplasm;0.00185393726911236!GO:0016272;prefoldin complex;0.00192569617492003!GO:0006611;protein export from nucleus;0.00193557867854116!GO:0051789;response to protein stimulus;0.00193998279284714!GO:0006986;response to unfolded protein;0.00193998279284714!GO:0000082;G1/S transition of mitotic cell cycle;0.0019602607620503!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0019993252968691!GO:0031570;DNA integrity checkpoint;0.00203295689957285!GO:0042393;histone binding;0.00231395114341905!GO:0008312;7S RNA binding;0.00242414245044419!GO:0015980;energy derivation by oxidation of organic compounds;0.0024677211433963!GO:0008408;3'-5' exonuclease activity;0.00250558118867249!GO:0006950;response to stress;0.00255315716077878!GO:0006289;nucleotide-excision repair;0.00256999483664926!GO:0016126;sterol biosynthetic process;0.00262410093635442!GO:0048037;cofactor binding;0.00273761843778048!GO:0051540;metal cluster binding;0.0027961466316405!GO:0051536;iron-sulfur cluster binding;0.0027961466316405!GO:0035258;steroid hormone receptor binding;0.00289614582028506!GO:0008017;microtubule binding;0.00295814751728141!GO:0031410;cytoplasmic vesicle;0.00324561778751079!GO:0006778;porphyrin metabolic process;0.00325914242686751!GO:0033013;tetrapyrrole metabolic process;0.00325914242686751!GO:0019843;rRNA binding;0.00340741975070521!GO:0047485;protein N-terminus binding;0.00342024801683535!GO:0045786;negative regulation of progression through cell cycle;0.00343890756767016!GO:0000178;exosome (RNase complex);0.00360906449107002!GO:0000781;chromosome, telomeric region;0.00372105164789158!GO:0005876;spindle microtubule;0.00372105164789158!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00374767448254242!GO:0006417;regulation of translation;0.00377822426646972!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00382957326079454!GO:0045047;protein targeting to ER;0.00382957326079454!GO:0006595;polyamine metabolic process;0.00392244340951027!GO:0046365;monosaccharide catabolic process;0.00404151932067161!GO:0048523;negative regulation of cellular process;0.0040729692096176!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0040729692096176!GO:0009124;nucleoside monophosphate biosynthetic process;0.00428940992188157!GO:0009123;nucleoside monophosphate metabolic process;0.00428940992188157!GO:0006783;heme biosynthetic process;0.00440619649817518!GO:0008652;amino acid biosynthetic process;0.00444098694187046!GO:0030133;transport vesicle;0.00453164200025705!GO:0031123;RNA 3'-end processing;0.00454142685117301!GO:0043601;nuclear replisome;0.00456480132983572!GO:0030894;replisome;0.00456480132983572!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00485280446244352!GO:0016584;nucleosome positioning;0.00506337444548461!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00506337444548461!GO:0043624;cellular protein complex disassembly;0.00521999036835276!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00527682168457333!GO:0000152;nuclear ubiquitin ligase complex;0.00533369465044256!GO:0006650;glycerophospholipid metabolic process;0.00533369465044256!GO:0032259;methylation;0.00545675854570751!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00555519275831434!GO:0009112;nucleobase metabolic process;0.00577850342238203!GO:0051053;negative regulation of DNA metabolic process;0.00586639979311632!GO:0004532;exoribonuclease activity;0.00610237037660311!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00610237037660311!GO:0006096;glycolysis;0.00615482501786194!GO:0030118;clathrin coat;0.00615482501786194!GO:0030134;ER to Golgi transport vesicle;0.00632410668634761!GO:0008022;protein C-terminus binding;0.00635447271055286!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0063557919142899!GO:0018196;peptidyl-asparagine modification;0.0063557919142899!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0063557919142899!GO:0006506;GPI anchor biosynthetic process;0.006625298794846!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.006625298794846!GO:0015002;heme-copper terminal oxidase activity;0.006625298794846!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.006625298794846!GO:0004129;cytochrome-c oxidase activity;0.006625298794846!GO:0048487;beta-tubulin binding;0.006625298794846!GO:0019320;hexose catabolic process;0.00662779430195313!GO:0030658;transport vesicle membrane;0.00663316410772381!GO:0046164;alcohol catabolic process;0.00673030405732598!GO:0022406;membrane docking;0.0070207906448009!GO:0048278;vesicle docking;0.0070207906448009!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00707526283376699!GO:0006378;mRNA polyadenylation;0.00716733286652706!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00717177952474238!GO:0030663;COPI coated vesicle membrane;0.00726027483286077!GO:0030126;COPI vesicle coat;0.00726027483286077!GO:0044262;cellular carbohydrate metabolic process;0.0073113307146818!GO:0007010;cytoskeleton organization and biogenesis;0.00752811109759406!GO:0043488;regulation of mRNA stability;0.00762052428349096!GO:0043487;regulation of RNA stability;0.00762052428349096!GO:0045045;secretory pathway;0.00767782445635032!GO:0003746;translation elongation factor activity;0.00773757420839704!GO:0042168;heme metabolic process;0.00777855577718102!GO:0016407;acetyltransferase activity;0.0078290409077294!GO:0043022;ribosome binding;0.00783500436775215!GO:0007004;telomere maintenance via telomerase;0.00785696335115215!GO:0046914;transition metal ion binding;0.00785801313045375!GO:0022411;cellular component disassembly;0.00803473604124164!GO:0006607;NLS-bearing substrate import into nucleus;0.00803873122187552!GO:0005832;chaperonin-containing T-complex;0.00803873122187552!GO:0030521;androgen receptor signaling pathway;0.0081755412369804!GO:0000339;RNA cap binding;0.00823585755255952!GO:0006695;cholesterol biosynthetic process;0.0083202169385139!GO:0030127;COPII vesicle coat;0.00870334563400049!GO:0012507;ER to Golgi transport vesicle membrane;0.00870334563400049!GO:0006376;mRNA splice site selection;0.00878339159220222!GO:0000389;nuclear mRNA 3'-splice site recognition;0.00878339159220222!GO:0044450;microtubule organizing center part;0.00905497812162623!GO:0000077;DNA damage checkpoint;0.00920818296959399!GO:0006730;one-carbon compound metabolic process;0.00921131775887746!GO:0051287;NAD binding;0.00929042426486469!GO:0006400;tRNA modification;0.00939035637337868!GO:0006118;electron transport;0.00964947159024821!GO:0032984;macromolecular complex disassembly;0.0096778206430166!GO:0009161;ribonucleoside monophosphate metabolic process;0.0097132678211168!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0097132678211168!GO:0000097;sulfur amino acid biosynthetic process;0.0097132678211168!GO:0000228;nuclear chromosome;0.00978214781992449!GO:0006505;GPI anchor metabolic process;0.00978364292036939!GO:0046966;thyroid hormone receptor binding;0.00978364292036939!GO:0035267;NuA4 histone acetyltransferase complex;0.00985648828455418!GO:0004674;protein serine/threonine kinase activity;0.0101941803933845!GO:0006904;vesicle docking during exocytosis;0.0101941803933845!GO:0042054;histone methyltransferase activity;0.0102128731191532!GO:0009308;amine metabolic process;0.0102352635188554!GO:0003887;DNA-directed DNA polymerase activity;0.0102403311441615!GO:0030660;Golgi-associated vesicle membrane;0.0104319715944861!GO:0043189;H4/H2A histone acetyltransferase complex;0.0104899664461459!GO:0008139;nuclear localization sequence binding;0.0104969148820086!GO:0000726;non-recombinational repair;0.0106224847934958!GO:0006541;glutamine metabolic process;0.0108804895774329!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0112549471387317!GO:0000080;G1 phase of mitotic cell cycle;0.0112634812096935!GO:0032561;guanyl ribonucleotide binding;0.0117420630426968!GO:0019001;guanyl nucleotide binding;0.0117420630426968!GO:0031577;spindle checkpoint;0.0119340744232579!GO:0005663;DNA replication factor C complex;0.0122037166804556!GO:0043414;biopolymer methylation;0.0122091312779769!GO:0051297;centrosome organization and biogenesis;0.0122091312779769!GO:0031023;microtubule organizing center organization and biogenesis;0.0122091312779769!GO:0004523;ribonuclease H activity;0.0122790040163587!GO:0008287;protein serine/threonine phosphatase complex;0.0128793156123246!GO:0016481;negative regulation of transcription;0.0131721817266679!GO:0009066;aspartate family amino acid metabolic process;0.0132698464111639!GO:0043241;protein complex disassembly;0.0133867206109978!GO:0009067;aspartate family amino acid biosynthetic process;0.0133968639310629!GO:0000287;magnesium ion binding;0.0136985152629615!GO:0005680;anaphase-promoting complex;0.0140174420111662!GO:0006278;RNA-dependent DNA replication;0.0140181530683421!GO:0006497;protein amino acid lipidation;0.0140250452152881!GO:0030518;steroid hormone receptor signaling pathway;0.0140923059555241!GO:0030119;AP-type membrane coat adaptor complex;0.0145030297801555!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0145665569219416!GO:0006643;membrane lipid metabolic process;0.0147161940343912!GO:0042802;identical protein binding;0.0147908976896277!GO:0000118;histone deacetylase complex;0.0148293766191862!GO:0009303;rRNA transcription;0.0148293766191862!GO:0031901;early endosome membrane;0.0151234732994368!GO:0007021;tubulin folding;0.0152496260431977!GO:0030218;erythrocyte differentiation;0.0155097369985065!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.0156046289426798!GO:0030137;COPI-coated vesicle;0.0156385302895079!GO:0000086;G2/M transition of mitotic cell cycle;0.0159868525414486!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.0160188480747564!GO:0000910;cytokinesis;0.0162749529672985!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0163566984064653!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0167987550832641!GO:0015036;disulfide oxidoreductase activity;0.0168550015137704!GO:0008632;apoptotic program;0.0169493454600115!GO:0006807;nitrogen compound metabolic process;0.0169817524561734!GO:0005996;monosaccharide metabolic process;0.0172981044835374!GO:0006301;postreplication repair;0.0174556184730997!GO:0007050;cell cycle arrest;0.0175441640440892!GO:0008270;zinc ion binding;0.017593644700463!GO:0009081;branched chain family amino acid metabolic process;0.0176923976144697!GO:0005652;nuclear lamina;0.0183702917513843!GO:0030176;integral to endoplasmic reticulum membrane;0.0184564364504505!GO:0019783;small conjugating protein-specific protease activity;0.0184693704403241!GO:0006733;oxidoreduction coenzyme metabolic process;0.0185826315247693!GO:0001522;pseudouridine synthesis;0.018712690584825!GO:0040029;regulation of gene expression, epigenetic;0.0191697939530574!GO:0008170;N-methyltransferase activity;0.0191697939530574!GO:0019318;hexose metabolic process;0.0195661377256463!GO:0008234;cysteine-type peptidase activity;0.0197544081372603!GO:0030132;clathrin coat of coated pit;0.020276349931298!GO:0006740;NADPH regeneration;0.0203352393271662!GO:0006098;pentose-phosphate shunt;0.0203352393271662!GO:0006360;transcription from RNA polymerase I promoter;0.0205411455127263!GO:0008320;protein transmembrane transporter activity;0.0208286234463322!GO:0048519;negative regulation of biological process;0.0210598780805229!GO:0009116;nucleoside metabolic process;0.0212154274900202!GO:0042158;lipoprotein biosynthetic process;0.0212949615621552!GO:0030131;clathrin adaptor complex;0.0214817021415098!GO:0000123;histone acetyltransferase complex;0.0214817021415098!GO:0031326;regulation of cellular biosynthetic process;0.0215464927726203!GO:0065007;biological regulation;0.0218184566665513!GO:0009113;purine base biosynthetic process;0.0223553971430729!GO:0030496;midbody;0.0224055812000921!GO:0008180;signalosome;0.022460937219902!GO:0033116;ER-Golgi intermediate compartment membrane;0.0224668282029932!GO:0000209;protein polyubiquitination;0.0225199320301415!GO:0005773;vacuole;0.0225924901678079!GO:0031902;late endosome membrane;0.0227534166162944!GO:0000793;condensed chromosome;0.0228950091656644!GO:0046128;purine ribonucleoside metabolic process;0.0229278610107219!GO:0042278;purine nucleoside metabolic process;0.0229278610107219!GO:0008156;negative regulation of DNA replication;0.0232586374876605!GO:0017056;structural constituent of nuclear pore;0.0236937096376515!GO:0000930;gamma-tubulin complex;0.0237979192051765!GO:0030262;apoptotic nuclear changes;0.0238428994850743!GO:0031371;ubiquitin conjugating enzyme complex;0.0238428994850743!GO:0007346;regulation of progression through mitotic cell cycle;0.0239213699820973!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.0242236054068607!GO:0016835;carbon-oxygen lyase activity;0.0243580611201267!GO:0004843;ubiquitin-specific protease activity;0.0244707005577817!GO:0000175;3'-5'-exoribonuclease activity;0.0248381506370368!GO:0022884;macromolecule transmembrane transporter activity;0.0248381506370368!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0248381506370368!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.0251001353097761!GO:0030508;thiol-disulfide exchange intermediate activity;0.0251556189691164!GO:0016279;protein-lysine N-methyltransferase activity;0.0261211340083091!GO:0018024;histone-lysine N-methyltransferase activity;0.0261211340083091!GO:0016278;lysine N-methyltransferase activity;0.0261211340083091!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0261816509179531!GO:0045039;protein import into mitochondrial inner membrane;0.0261816509179531!GO:0031625;ubiquitin protein ligase binding;0.0263579194917583!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0265820710828353!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0265820710828353!GO:0009126;purine nucleoside monophosphate metabolic process;0.0265820710828353!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0265820710828353!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0265903869813478!GO:0010257;NADH dehydrogenase complex assembly;0.0265903869813478!GO:0033108;mitochondrial respiratory chain complex assembly;0.0265903869813478!GO:0005853;eukaryotic translation elongation factor 1 complex;0.026915040571047!GO:0043631;RNA polyadenylation;0.0269326621657398!GO:0007098;centrosome cycle;0.0271837579878597!GO:0006672;ceramide metabolic process;0.0271837579878597!GO:0006406;mRNA export from nucleus;0.0271837579878597!GO:0016585;chromatin remodeling complex;0.0273559456950422!GO:0003702;RNA polymerase II transcription factor activity;0.0273632446607374!GO:0008299;isoprenoid biosynthetic process;0.0285223210440071!GO:0044438;microbody part;0.0290699117668797!GO:0044439;peroxisomal part;0.0290699117668797!GO:0042770;DNA damage response, signal transduction;0.0291329176175263!GO:0042026;protein refolding;0.0293277338703158!GO:0006767;water-soluble vitamin metabolic process;0.0302129044699512!GO:0016408;C-acyltransferase activity;0.0305415682031228!GO:0032039;integrator complex;0.030578029781382!GO:0050681;androgen receptor binding;0.0312897688722793!GO:0008144;drug binding;0.0313702875744629!GO:0012506;vesicle membrane;0.0321154928870465!GO:0051318;G1 phase;0.0323998259760052!GO:0000305;response to oxygen radical;0.0323998259760052!GO:0006308;DNA catabolic process;0.0323998259760052!GO:0003725;double-stranded RNA binding;0.0324560611133837!GO:0005851;eukaryotic translation initiation factor 2B complex;0.0324560611133837!GO:0016790;thiolester hydrolase activity;0.0324560611133837!GO:0031252;leading edge;0.0324968525992247!GO:0006220;pyrimidine nucleotide metabolic process;0.0330568537462629!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.033338920821309!GO:0031057;negative regulation of histone modification;0.0334156344214783!GO:0035067;negative regulation of histone acetylation;0.0334156344214783!GO:0004520;endodeoxyribonuclease activity;0.0335287217988546!GO:0051656;establishment of organelle localization;0.0341823933918725!GO:0006379;mRNA cleavage;0.0349422907290887!GO:0016197;endosome transport;0.0352245415802277!GO:0030659;cytoplasmic vesicle membrane;0.0354922401618488!GO:0006610;ribosomal protein import into nucleus;0.0355836771909811!GO:0006644;phospholipid metabolic process;0.0362345609670056!GO:0065009;regulation of a molecular function;0.037061428401941!GO:0006415;translational termination;0.0371081405667606!GO:0008536;Ran GTPase binding;0.0376320026006203!GO:0008097;5S rRNA binding;0.0376320026006203!GO:0046519;sphingoid metabolic process;0.0376957575511604!GO:0030145;manganese ion binding;0.0377598476504273!GO:0030911;TPR domain binding;0.03855001753092!GO:0001889;liver development;0.0387942172467792!GO:0005666;DNA-directed RNA polymerase III complex;0.0389104559795416!GO:0033170;DNA-protein loading ATPase activity;0.0389104559795416!GO:0003689;DNA clamp loader activity;0.0389104559795416!GO:0016453;C-acetyltransferase activity;0.0389104559795416!GO:0004540;ribonuclease activity;0.0396496395917892!GO:0004448;isocitrate dehydrogenase activity;0.0397560477145645!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0397569014529853!GO:0003985;acetyl-CoA C-acetyltransferase activity;0.0399981429320009!GO:0031903;microbody membrane;0.0410030136359879!GO:0005778;peroxisomal membrane;0.0410030136359879!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0411690451048195!GO:0005487;nucleocytoplasmic transporter activity;0.0413948144242945!GO:0005784;translocon complex;0.0419347419652502!GO:0005938;cell cortex;0.0420803844486263!GO:0004239;methionyl aminopeptidase activity;0.042501905337923!GO:0006596;polyamine biosynthetic process;0.0426823588705101!GO:0004536;deoxyribonuclease activity;0.0435672800078218!GO:0004221;ubiquitin thiolesterase activity;0.0435672800078218!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.044133207755779!GO:0032287;myelin maintenance in the peripheral nervous system;0.044133207755779!GO:0032838;cell projection cytoplasm;0.044133207755779!GO:0033081;regulation of T cell differentiation in the thymus;0.044133207755779!GO:0043217;myelin maintenance;0.044133207755779!GO:0060087;relaxation of vascular smooth muscle;0.044133207755779!GO:0032839;dendrite cytoplasm;0.044133207755779!GO:0005732;small nucleolar ribonucleoprotein complex;0.0442190791677022!GO:0006555;methionine metabolic process;0.0445098977079902!GO:0008601;protein phosphatase type 2A regulator activity;0.0445936652612085!GO:0030983;mismatched DNA binding;0.0448488788665937!GO:0005754;mitochondrial proton-transporting ATP synthase, catalytic core;0.0455328031466179!GO:0000275;mitochondrial proton-transporting ATP synthase complex, catalytic core F(1);0.0455328031466179!GO:0045267;proton-transporting ATP synthase, catalytic core;0.0455328031466179!GO:0050000;chromosome localization;0.0457596706918218!GO:0051303;establishment of chromosome localization;0.0457596706918218!GO:0003756;protein disulfide isomerase activity;0.0457596706918218!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0457596706918218!GO:0019206;nucleoside kinase activity;0.046233344598348!GO:0030174;regulation of DNA replication initiation;0.0464222714164641!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0476896747264088!GO:0000323;lytic vacuole;0.0478083096295992!GO:0005764;lysosome;0.0478083096295992!GO:0030433;ER-associated protein catabolic process;0.0489065373284369!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0489065373284369!GO:0030320;cellular monovalent inorganic anion homeostasis;0.0491724833981439!GO:0055083;monovalent inorganic anion homeostasis;0.0491724833981439!GO:0055064;chloride ion homeostasis;0.0491724833981439!GO:0030644;cellular chloride ion homeostasis;0.0491724833981439!GO:0005777;peroxisome;0.0494200656847584!GO:0042579;microbody;0.0494200656847584 | |||
|sample_id=10825 | |||
|sample_note= | |||
|sample_sex=female | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=GATA6:3.89492946145;MYB:1.95302701518;ELK1,4_GABP{A,B1}:1.7984400301;CDX1,2,4:1.55652904788;STAT5{A,B}:1.54767088082;E2F1..5:1.50856962796;POU3F1..4:1.50664070434;NFY{A,B,C}:1.45040917719;PBX1:1.38909816799;NRF1:1.26023236398;NR5A1,2:1.24768439588;POU2F1..3:1.17083994863;ZBTB16:1.11506109927;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.06589726827;ZNF143:1.02888059816;NR6A1:0.978202157437;HOX{A6,A7,B6,B7}:0.915199434159;HOXA9_MEIS1:0.907274834697;RBPJ:0.851716562085;OCT4_SOX2{dimer}:0.780653235398;FOXQ1:0.773474075855;STAT1,3:0.739696855058;ADNP_IRX_SIX_ZHX:0.737290816351;HOX{A5,B5}:0.725567991216;YY1:0.668887185213;AHR_ARNT_ARNT2:0.618887532456;NFIX:0.598873591102;ESRRA:0.593351016471;RORA:0.578640183481;PITX1..3:0.578604202907;CRX:0.575221573473;PAX8:0.568114682203;NR1H4:0.535451955709;T:0.531814152781;HES1:0.519136815466;NANOG:0.51663278489;NKX3-2:0.495541372723;SPZ1:0.473826958849;BREu{core}:0.464113175192;NFE2:0.459838010618;PAX3,7:0.455758322542;SOX{8,9,10}:0.408022670487;CUX2:0.393339428333;NKX2-3_NKX2-5:0.377246108553;ZNF148:0.365035176997;NKX2-1,4:0.342526595107;IKZF1:0.324968850224;PRRX1,2:0.313748131344;ELF1,2,4:0.287732305957;IKZF2:0.272081344086;NANOG{mouse}:0.26420262517;SMAD1..7,9:0.250546751412;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.248409870319;AR:0.245648939448;ONECUT1,2:0.240748149689;GFI1:0.208417261885;SNAI1..3:0.190672597552;EVI1:0.190087045365;HOX{A4,D4}:0.159778748999;FOXA2:0.102681816851;HNF4A_NR2F1,2:0.0677990263907;bHLH_family:0.0488432242551;CREB1:0.0467582825305;HIF1A:0.0395822768305;VSX1,2:0.0284647147703;ZEB1:0.0267273981973;RXRA_VDR{dimer}:0.0222764414792;POU6F1:0.0202520347354;ALX1:0.011180933743;LEF1_TCF7_TCF7L1,2:0.0103101908835;HAND1,2:-0.00634202714009;EN1,2:-0.0122192351934;PAX6:-0.0537074403386;TOPORS:-0.056981109573;TFDP1:-0.0722670530596;POU1F1:-0.089857143432;ATF4:-0.100289348153;AIRE:-0.114818313454;NKX6-1,2:-0.124709404556;FOXD3:-0.146884665337;PAX1,9:-0.1708023226;FOSL2:-0.171377158361;CEBPA,B_DDIT3:-0.172363033536;ARID5B:-0.173285691645;SPIB:-0.176497396219;HLF:-0.177753023389;FOX{F1,F2,J1}:-0.195124836479;ATF5_CREB3:-0.199784305383;MEF2{A,B,C,D}:-0.20638443934;HNF1A:-0.210466653314;NFE2L2:-0.211707147948;POU5F1:-0.250847518793;SP1:-0.289720407748;PPARG:-0.301325006336;SPI1:-0.315410440598;MYOD1:-0.329625816175;HSF1,2:-0.331341258376;RUNX1..3:-0.332822832624;FOXN1:-0.337020418505;RXR{A,B,G}:-0.337393891602;ZNF384:-0.348579314472;PAX2:-0.355430435051;TEF:-0.356578603899;RFX2..5_RFXANK_RFXAP:-0.363286263297;BACH2:-0.381108552581;MAFB:-0.393602910601;NFKB1_REL_RELA:-0.40775439036;FOS_FOS{B,L1}_JUN{B,D}:-0.417960048408;FOXP1:-0.420991977604;UFEwm:-0.454174246767;GATA4:-0.457981028174;ETS1,2:-0.462741704612;XCPE1{core}:-0.462949225508;STAT2,4,6:-0.480357964439;NKX3-1:-0.483508588277;FOXP3:-0.497449579493;SOX5:-0.507883697083;RFX1:-0.510699343334;PAX4:-0.521143340059;KLF4:-0.521962348168;REST:-0.595624975116;NKX2-2,8:-0.597097999946;ZBTB6:-0.59712774543;XBP1:-0.602740768723;NFE2L1:-0.60576024786;PATZ1:-0.612335403644;TGIF1:-0.61617273844;DMAP1_NCOR{1,2}_SMARC:-0.624450750465;SOX2:-0.626463418231;EGR1..3:-0.627002910473;PDX1:-0.638507066156;RREB1:-0.649505244474;NHLH1,2:-0.680168467091;LHX3,4:-0.681297648321;CDC5L:-0.688211547907;NFIL3:-0.692958958624;ZFP161:-0.695244881406;FOXM1:-0.707032505542;SOX17:-0.72015902332;LMO2:-0.730455097083;TFAP4:-0.764471452523;FOX{I1,J2}:-0.773484645432;ATF2:-0.778165233864;IRF7:-0.784762607227;GTF2I:-0.81062870291;EP300:-0.811080075866;TLX2:-0.831308312127;ZNF238:-0.8398913342;TP53:-0.860301002433;DBP:-0.867084891955;NFATC1..3:-0.880174788029;HMX1:-0.885948216136;GTF2A1,2:-0.894253728543;SREBF1,2:-0.90481906428;TEAD1:-0.905982201347;MYBL2:-0.914617190456;MED-1{core}:-0.941350449564;TBP:-0.948905487482;NR3C1:-0.96945942591;HBP1_HMGB_SSRP1_UBTF:-0.982410847797;ZNF423:-1.01547588771;BPTF:-1.02508336133;MZF1:-1.03877447513;JUN:-1.04934197593;IRF1,2:-1.06156638749;FOX{D1,D2}:-1.06884952162;HMGA1,2:-1.07441902349;ALX4:-1.08383266138;ZIC1..3:-1.1052277191;SRF:-1.11249396472;GCM1,2:-1.1834085898;MYFfamily:-1.19032061793;MAZ:-1.23016387116;EBF1:-1.23314051288;ESR1:-1.24738673241;PRDM1:-1.26754604997;MTF1:-1.28738914026;HIC1:-1.30064948708;TLX1..3_NFIC{dimer}:-1.32668333279;TAL1_TCF{3,4,12}:-1.35845841514;GLI1..3:-1.37556212012;FOXO1,3,4:-1.39977115674;TBX4,5:-1.4216586389;ATF6:-1.45673911346;PAX5:-1.46182306306;GZF1:-1.49026318284;MTE{core}:-1.4921637499;GFI1B:-1.52420035927;TFAP2{A,C}:-1.54443487541;TFAP2B:-1.70397732952;FOXL1:-1.71420376703;TFCP2:-2.2148000744 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10825-111C6;search_select_hide=table117:FF:10825-111C6 | |||
}} | }} |
Latest revision as of 15:07, 3 June 2020
Name: | chronic myelogenous leukemia cell line:K562 ENCODE, biol_rep2 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs12335 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12335
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12335
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.03 |
10 | 10 | 0.0954 |
100 | 100 | 0.218 |
101 | 101 | 0.658 |
102 | 102 | 0.391 |
103 | 103 | 0.731 |
104 | 104 | 0.65 |
105 | 105 | 0.832 |
106 | 106 | 0.0276 |
107 | 107 | 0.0116 |
108 | 108 | 0.718 |
109 | 109 | 0.0186 |
11 | 11 | 0.147 |
110 | 110 | 0.157 |
111 | 111 | 0.523 |
112 | 112 | 0.801 |
113 | 113 | 0.0952 |
114 | 114 | 0.0218 |
115 | 115 | 0.464 |
116 | 116 | 0.7 |
117 | 117 | 0.0102 |
118 | 118 | 0.196 |
119 | 119 | 0.588 |
12 | 12 | 0.827 |
120 | 120 | 0.469 |
121 | 121 | 0.961 |
122 | 122 | 0.0427 |
123 | 123 | 0.837 |
124 | 124 | 0.453 |
125 | 125 | 0.456 |
126 | 126 | 0.135 |
127 | 127 | 0.0942 |
128 | 128 | 0.0578 |
129 | 129 | 0.458 |
13 | 13 | 0.00155 |
130 | 130 | 0.0495 |
131 | 131 | 0.356 |
132 | 132 | 0.159 |
133 | 133 | 0.0625 |
134 | 134 | 0.958 |
135 | 135 | 0.296 |
136 | 136 | 0.0309 |
137 | 137 | 0.279 |
138 | 138 | 0.558 |
139 | 139 | 0.424 |
14 | 14 | 0.491 |
140 | 140 | 0.026 |
141 | 141 | 0.0313 |
142 | 142 | 0.744 |
143 | 143 | 0.576 |
144 | 144 | 0.504 |
145 | 145 | 0.932 |
146 | 146 | 0.887 |
147 | 147 | 0.737 |
148 | 148 | 0.784 |
149 | 149 | 0.215 |
15 | 15 | 0.463 |
150 | 150 | 0.555 |
151 | 151 | 0.383 |
152 | 152 | 0.125 |
153 | 153 | 0.707 |
154 | 154 | 0.337 |
155 | 155 | 0.194 |
156 | 156 | 0.482 |
157 | 157 | 0.352 |
158 | 158 | 0.987 |
159 | 159 | 0.159 |
16 | 16 | 0.883 |
160 | 160 | 0.944 |
161 | 161 | 0.0323 |
162 | 162 | 0.708 |
163 | 163 | 0.403 |
164 | 164 | 0.459 |
165 | 165 | 0.964 |
166 | 166 | 0.0345 |
167 | 167 | 0.327 |
168 | 168 | 0.749 |
169 | 169 | 0.711 |
17 | 17 | 0.799 |
18 | 18 | 0.992 |
19 | 19 | 0.903 |
2 | 2 | 0.22 |
20 | 20 | 0.0702 |
21 | 21 | 0.444 |
22 | 22 | 0.57 |
23 | 23 | 0.0224 |
24 | 24 | 0.16 |
25 | 25 | 0.324 |
26 | 26 | 0.177 |
27 | 27 | 0.321 |
28 | 28 | 0.549 |
29 | 29 | 0.028 |
3 | 3 | 0.455 |
30 | 30 | 0.168 |
31 | 31 | 0.562 |
32 | 32 | 0.0643 |
33 | 33 | 0.0478 |
34 | 34 | 0.392 |
35 | 35 | 0.356 |
36 | 36 | 0.0269 |
37 | 37 | 0.235 |
38 | 38 | 0.302 |
39 | 39 | 0.2 |
4 | 4 | 0.0663 |
40 | 40 | 0.137 |
41 | 41 | 0.962 |
42 | 42 | 0.354 |
43 | 43 | 0.622 |
44 | 44 | 0.516 |
45 | 45 | 0.512 |
46 | 46 | 0.508 |
47 | 47 | 0.0347 |
48 | 48 | 0.181 |
49 | 49 | 0.188 |
5 | 5 | 0.797 |
50 | 50 | 0.961 |
51 | 51 | 0.955 |
52 | 52 | 0.0257 |
53 | 53 | 0.888 |
54 | 54 | 0.719 |
55 | 55 | 0.0214 |
56 | 56 | 0.923 |
57 | 57 | 0.451 |
58 | 58 | 0.47 |
59 | 59 | 0.944 |
6 | 6 | 0.279 |
60 | 60 | 0.343 |
61 | 61 | 0.0604 |
62 | 62 | 0.367 |
63 | 63 | 0.428 |
64 | 64 | 0.422 |
65 | 65 | 0.579 |
66 | 66 | 8.17077e-6 |
67 | 67 | 0.616 |
68 | 68 | 0.17 |
69 | 69 | 0.787 |
7 | 7 | 0.0516 |
70 | 70 | 0.429 |
71 | 71 | 0.041 |
72 | 72 | 0.455 |
73 | 73 | 0.951 |
74 | 74 | 0.699 |
75 | 75 | 0.00623 |
76 | 76 | 0.692 |
77 | 77 | 0.453 |
78 | 78 | 0.00151 |
79 | 79 | 0.0803 |
8 | 8 | 0.559 |
80 | 80 | 0.199 |
81 | 81 | 0.346 |
82 | 82 | 0.984 |
83 | 83 | 0.131 |
84 | 84 | 0.505 |
85 | 85 | 0.198 |
86 | 86 | 0.856 |
87 | 87 | 0.0558 |
88 | 88 | 0.98 |
89 | 89 | 0.569 |
9 | 9 | 0.56 |
90 | 90 | 0.494 |
91 | 91 | 0.0613 |
92 | 92 | 0.524 |
93 | 93 | 0.987 |
94 | 94 | 0.754 |
95 | 95 | 0.0264 |
96 | 96 | 0.651 |
97 | 97 | 0.348 |
98 | 98 | 0.32 |
99 | 99 | 0.5 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12335
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0100664 K-562 cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
1036 (chronic leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0102580 (chronic myeloid leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0100740 (myeloid leukemia cell line sample)
0100664 (K-562 cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)