FF:10832-111D4: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet= | |DRA_sample_Accession=CAGE@SAMD00005554 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |accession_numbers=CAGE;DRX007809;DRR008681;DRZ000106;DRZ001491;DRZ011456;DRZ012841 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:8692 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0101883,FF:0100740 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
| Line 35: | Line 41: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M4eo%2529%2520cell%2520line%253aEoL-1.CNhs13056.10832-111D4.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M4eo%2529%2520cell%2520line%253aEoL-1.CNhs13056.10832-111D4.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M4eo%2529%2520cell%2520line%253aEoL-1.CNhs13056.10832-111D4.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M4eo%2529%2520cell%2520line%253aEoL-1.CNhs13056.10832-111D4.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M4eo%2529%2520cell%2520line%253aEoL-1.CNhs13056.10832-111D4.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10832-111D4 | |id=FF:10832-111D4 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0000210;;FF:0101883 | ||
|is_obsolete= | |||
|library_id=CNhs13056 | |||
|library_id_phase_based=2:CNhs13056 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10832 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10832 | |||
|name=acute myeloid leukemia (FAB M4eo) cell line:EoL-1 | |name=acute myeloid leukemia (FAB M4eo) cell line:EoL-1 | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
| Line 42: | Line 60: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs13056,LSID1000,release012,COMPLETED | |profile_hcage=CNhs13056,LSID1000,release012,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.0323390519651663,0,0,0,0,0.228012816987074,0,-0.252449415398504,0.293254118421454,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0886449064180952,0,0,0,0,0,0.0230028289641482,0,0,0.282997948093651,0,0,0,0,0,0,0,0,0,0,0,0,-0.172084145616109,0.0646781039303325,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0.358830056255803,0,-0.0839305477320758,0,0.0737867440252642,0,0,0.0734354780547723,0,0,0,0,0,0,0,0,0,0,0.57170851473435,0,0,0.415954537872514,0,0,0,-0.082275836862518,0,0,0,0,0,-0.0243291770795736,-0.552571649267773,0.0323390519651663,0,0,-0.0366083055262263,-0.064678803506424,0.0323390519651663,0,0.120960725232206,0,0.157946013304178,0.101418189943109,0,0,0,0,0,0,0.0646781039303325,0,0,0,0,0,0,0,0,0,0,0.297668799278256,0.0646781039303325,0,0,-0.126024924791884,-0.284552760197831,0,0,0.0646781039303325,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0,0.157946013304178,0,0,0.170779105267869,0.120960725232206,0,0,0.0646781039303325,0,0,0,0,-0.247178875285564,0.0163522689698209,0.423831435390085,0.0272639627443974,0,0.0646781039303325,-0.280760487720126,0,0,0,0,0,0,0,0.120960725232206,0,-0.128119866952565,0,-0.0504125515893149,0,0,0,0,-0.0186252810838506,0.110482306974106,0,-0.088868508515575,-0.00366615714703575,0,0,0,0,0.0704433533918505,0,8.12414384650934e-05,-0.0180420643930849,-0.221611588102807,-0.551732485729957,0.00896560714915048,0,0,0,-0.311105361246252,-0.953700809462556,0,0,-0.121779851751874,-0.149010566595493,0,0,-0.391044581551635,0,-0.434940918527203,-0.0604397418968705,0,0.485762372832834,0,0,0,0,0,0,0,0,0,0,0,-0.0574934668214365,-0.111522273545529,0.151590145509294,0,0,0,-0.399844588783548,0,-0.0138323107379372,-0.373286155956567,-0.204953872554528,-0.063637992213064,0.251060344646672,0,0.164041438080611,-0.165584514599386,-0.195081350827546,0.273242049260092,-0.0827237454408061,-0.189981719549847,0,-0.0207065639178705,0.339705490394959,0.0240911120106528,0.0144509161988364,0.0331392549457291,-0.97542714374522,-0.262153934974095,0,0,-0.0128308225489706,-0.376812940163969,0,0.141644319717819,0.150600162810496,-0.084587777855602,-0.67098743647571,-0.158740751263154,-0.0772954027660035,0.259448161570873,-0.0395325284566706,-0.0155106721513603,-0.160745020925146,-0.293581642632758,-0.117635524448897,0,-0.0877514257027229,-0.0742555280175662,-0.570445783973883,0.436391930957912,0,0.187521740966318,-0.0683442610773682,0,0.146952191739463,0.16723911100976,0,-0.0724626800406847,-0.457816505639206,0,0,0.237322387376415,0,0,0.138966740817022,-0.474814039099834,-0.017389238422105,0,0.107058962185009,-0.0447185992017715,-0.236805717736484,0,-0.0558598869966932,-0.202170761610805,-0.00503695398240284,0.0526444397653871,-0.000925366070448463,0.0971005106954847,-0.0251626661708142,-0.1943924446131,-0.129357607012848,-0.0584468268118252,0.130640219420003,-0.0520009060991751,-0.0366083055262263,-0.667979139558021,0,-0.0881268324752877,-0.210162025788965,-0.88354475051838,-0.0719172962967284,-0.0717677798233785,-0.317227797834553,0,-0.390864149398445,0,-0.00593582341814147,0.0073740117518231,-0.308257615932521,-0.0508063929950566,0.999996450694089,-0.0080993362293833,0,-0.104506124103175,-0.788130937773974,0,-0.135723143846782,-0.124678115799164,0,-0.0294063581024336,-0.697695966512583,-0.0434369036817664,-0.138989456679195,0,-0.669119433157451,0,0,-0.229393966981068,0.354538909566694,0.0646781039303325,-0.157738001678628,-0.142771749122872,-0.16229026045006,-0.115971073434934,0.0646781039303325,0,-0.645700337992725,0,0,-0.60592806381803,-0.0636048451378017,-0.555105220028301,0.523246301960847,0,-0.108622809454255,0,0,-0.177527765965176,0.21546632313344,-0.143504602354896,0,0.0646781039303325,-0.070466268470922,0,0,0.10773316156672,0,0,0,0,0,0,0,0,0,0.121281045299647,0.0334975168570125,0,0.109974132305894,0,0,0,0,0,0,0,0,-0.546341329426629,-0.0827401337136366,0.047761689591449,0,0,0,0,-0.151045298623142,-0.082275836862518,0,-0.010901981265426,0,0,0,0,0.206896208589678,0,0,0,0.19416542353673,0.19825090748822,-0.0462973115459844,0,0,0,0.0818756546540126,0.0646781039303325,0,0,0,-0.185001062575051,0,0,-0.00726520341510195,0,-0.0559057669509566,-0.0815818795468414,0,0.0070491608318543,-0.311141198286225,-0.98244200286632,0,0,-0.196669027859555,0,0,0.0900337978757229,-0.0823702229656663,0.120960725232206,0,0,0,0,0,0,0.120960725232206,0.174016334673705,0.188471044887045,0.120960725232206,0,0,0,0.0646781039303325,0,0,0,0.0323390519651663,0,-0.36122921818648,-0.0922240566585104,0,0,0,0,0,0,0,-0.0241060230789031,0.136503366020673,0,0,0,0,0,0,0,0,0.316658846738191,0,0,0,0,0,0.0737867440252642,0,0,0,0.0646781039303325,0.586508236842908,0,0,-0.156401406961308,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.123319086035448,-0.252449415398504,0,0,0,0,0,0,0,-0.27483329820609,0,0,0,0,0.00707635152322854,0,0,0,-0.104796384789156,0,0.228012816987074,0,0,0,0,0,0.0250013178586189,0.0853895526339345,0,0,0,0,0,0,0,0,0.525341895228316,0,0,0,0,0,-0.409012782696098,0,-0.28720751597291,-0.123202864573785,0,0,-0.172147990016938,0,0,0,0,0,0,0.096650258242415,0,0,0,0,0,0,0,0.0323390519651663,0,0.0646781039303325,0,0,0,0,0,0,0,0,0.0646781039303325,0,0,0,0,0,0,0.00227641722903833,0,0,0,0,0,0,0,0.0230028289641482,0,0,-0.0315524471844233,0,0,0,0,0,0,-0.159986158385767,-0.103805371695246,-0.124988841233281,0,0,0,-0.054385572482455,0.358830056255803,0,-0.0528303415052715,0,-0.00209928348856887,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0886449064180952,0,0,0,0,0,0,0,0,0,0,0,0,0.0853895526339345,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.120960725232206,0.060480362616103,0,0,0,0,0,0,0.0869493619567893,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.135447854864801,0,0,0,-0.092125504424838,0,0,0,0,0,0,0.120960725232206,0,0.0646781039303325,0,0,0,0,0,0,0,0,0,0,0,0.0646781039303325,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0646781039303325,0,0,0,-0.234649761682525,0,0,0,0,0,0,0,0,0,0,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| |||
|rna_box=111 | |rna_box=111 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
| Line 57: | Line 78: | ||
|rna_weight_ug=174.4461 | |rna_weight_ug=174.4461 | ||
|sample_age=33 | |sample_age=33 | ||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB0641 | |sample_cell_catalog=RCB0641 | ||
|sample_cell_line=EoL-1 cell | |sample_cell_line=EoL-1 cell | ||
| Line 69: | Line 91: | ||
|sample_ethnicity=J | |sample_ethnicity=J | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;5.77359122356537e-269!GO:0043227;membrane-bound organelle;8.15051385445621e-238!GO:0043231;intracellular membrane-bound organelle;2.31725265268256e-237!GO:0043226;organelle;6.39274453061986e-228!GO:0043229;intracellular organelle;4.48464553800355e-227!GO:0044422;organelle part;3.68338379349642e-165!GO:0044446;intracellular organelle part;1.38243965168452e-163!GO:0005737;cytoplasm;2.81568898915553e-156!GO:0032991;macromolecular complex;4.9926498144103e-124!GO:0005634;nucleus;8.30584938876684e-124!GO:0044237;cellular metabolic process;6.19895373456665e-123!GO:0044238;primary metabolic process;1.78602599748207e-117!GO:0043170;macromolecule metabolic process;1.10467181864239e-114!GO:0044444;cytoplasmic part;5.42369937818305e-114!GO:0030529;ribonucleoprotein complex;2.75986188474761e-111!GO:0044428;nuclear part;2.77859259661538e-105!GO:0043233;organelle lumen;5.99080449629146e-97!GO:0031974;membrane-enclosed lumen;5.99080449629146e-97!GO:0003723;RNA binding;5.97624023995599e-95!GO:0005739;mitochondrion;6.98063026354636e-78!GO:0043283;biopolymer metabolic process;2.93645182786507e-75!GO:0006396;RNA processing;8.82834546677933e-75!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.04604352083628e-71!GO:0010467;gene expression;1.53948411933476e-69!GO:0006412;translation;1.93869620725796e-66!GO:0031981;nuclear lumen;3.24189201029633e-63!GO:0005840;ribosome;2.04242949849678e-61!GO:0005515;protein binding;1.96233977843539e-60!GO:0043234;protein complex;3.38051247772589e-60!GO:0016071;mRNA metabolic process;3.27167580840321e-55!GO:0044429;mitochondrial part;2.89078052805377e-54!GO:0006259;DNA metabolic process;6.6666424494061e-54!GO:0003735;structural constituent of ribosome;1.35123823909792e-53!GO:0019538;protein metabolic process;1.36194250656598e-50!GO:0003676;nucleic acid binding;2.08245949216425e-50!GO:0008380;RNA splicing;8.91607499417081e-50!GO:0006397;mRNA processing;1.95702086973171e-49!GO:0044249;cellular biosynthetic process;4.07675307593929e-49!GO:0031967;organelle envelope;9.68230701521702e-49!GO:0031975;envelope;1.5218995339227e-48!GO:0009059;macromolecule biosynthetic process;3.59728657130391e-47!GO:0044267;cellular protein metabolic process;7.65639186254885e-47!GO:0044260;cellular macromolecule metabolic process;1.82640816679497e-46!GO:0009058;biosynthetic process;2.16837596451645e-46!GO:0033279;ribosomal subunit;1.62707170732699e-45!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.45399494818613e-44!GO:0031090;organelle membrane;3.49107535190394e-43!GO:0016043;cellular component organization and biogenesis;3.72213291678827e-42!GO:0033036;macromolecule localization;3.7716865543952e-41!GO:0005654;nucleoplasm;5.49261575365123e-39!GO:0015031;protein transport;1.4186119033603e-38!GO:0005829;cytosol;1.98250750963437e-38!GO:0006996;organelle organization and biogenesis;4.40823007095852e-38!GO:0045184;establishment of protein localization;3.60336632011926e-37!GO:0043228;non-membrane-bound organelle;4.71184863590566e-37!GO:0043232;intracellular non-membrane-bound organelle;4.71184863590566e-37!GO:0005681;spliceosome;8.73585803170615e-37!GO:0008104;protein localization;1.72707919990254e-36!GO:0065003;macromolecular complex assembly;3.30503873537306e-36!GO:0007049;cell cycle;1.66737576114331e-35!GO:0016070;RNA metabolic process;2.40691353797823e-35!GO:0006974;response to DNA damage stimulus;4.73374091285399e-34!GO:0005740;mitochondrial envelope;5.02204693848974e-34!GO:0046907;intracellular transport;2.48761894794927e-33!GO:0019866;organelle inner membrane;1.09603268722179e-32!GO:0000166;nucleotide binding;2.43111301549811e-32!GO:0005830;cytosolic ribosome (sensu Eukaryota);5.60301655575403e-32!GO:0006281;DNA repair;1.97761301884638e-31!GO:0031966;mitochondrial membrane;2.01788523681037e-31!GO:0022607;cellular component assembly;3.59311629588615e-31!GO:0044451;nucleoplasm part;3.27228266973443e-30!GO:0005743;mitochondrial inner membrane;5.11201134236175e-30!GO:0022402;cell cycle process;2.30552895824481e-29!GO:0005694;chromosome;2.71591244674164e-29!GO:0006886;intracellular protein transport;3.10054184677319e-29!GO:0000278;mitotic cell cycle;6.79574477218474e-29!GO:0044445;cytosolic part;6.58916541337262e-28!GO:0044427;chromosomal part;2.57561996393775e-25!GO:0051649;establishment of cellular localization;4.53011054951139e-25!GO:0005730;nucleolus;6.61180869259288e-25!GO:0022403;cell cycle phase;1.0752860581712e-24!GO:0031980;mitochondrial lumen;1.50408543106232e-24!GO:0005759;mitochondrial matrix;1.50408543106232e-24!GO:0051641;cellular localization;2.16065142887522e-24!GO:0000087;M phase of mitotic cell cycle;2.43909214595483e-24!GO:0051276;chromosome organization and biogenesis;4.26692776627322e-24!GO:0007067;mitosis;6.97808162744409e-24!GO:0015935;small ribosomal subunit;7.72074268321359e-24!GO:0005524;ATP binding;8.63984670989274e-24!GO:0006119;oxidative phosphorylation;1.10458809093053e-23!GO:0044455;mitochondrial membrane part;1.45230014615497e-23!GO:0016874;ligase activity;2.99464232344791e-23!GO:0032559;adenyl ribonucleotide binding;3.4703808030573e-23!GO:0006260;DNA replication;5.49072856466143e-23!GO:0016462;pyrophosphatase activity;6.29026616731834e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;7.01185626654252e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;7.99048071796898e-23!GO:0009719;response to endogenous stimulus;8.61422594453448e-23!GO:0015934;large ribosomal subunit;8.67422765416591e-23!GO:0022618;protein-RNA complex assembly;1.07405605446441e-22!GO:0030554;adenyl nucleotide binding;1.22071247660699e-22!GO:0032553;ribonucleotide binding;2.45379222503387e-22!GO:0032555;purine ribonucleotide binding;2.45379222503387e-22!GO:0042254;ribosome biogenesis and assembly;2.5424480427345e-22!GO:0017111;nucleoside-triphosphatase activity;3.8695390392016e-22!GO:0017076;purine nucleotide binding;4.49050422018845e-22!GO:0000279;M phase;1.29352886333381e-21!GO:0044265;cellular macromolecule catabolic process;3.6413897952833e-20!GO:0016887;ATPase activity;4.06819646761006e-20!GO:0006512;ubiquitin cycle;6.08046672114379e-20!GO:0051301;cell division;1.31475231593678e-19!GO:0042623;ATPase activity, coupled;1.85693608524373e-19!GO:0005746;mitochondrial respiratory chain;5.01081172009123e-19!GO:0043285;biopolymer catabolic process;1.59962057767963e-18!GO:0006325;establishment and/or maintenance of chromatin architecture;1.85205149223696e-18!GO:0006457;protein folding;2.25503602602075e-18!GO:0000398;nuclear mRNA splicing, via spliceosome;3.12886816392852e-18!GO:0000375;RNA splicing, via transesterification reactions;3.12886816392852e-18!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;3.12886816392852e-18!GO:0006323;DNA packaging;7.70013777181361e-18!GO:0005761;mitochondrial ribosome;1.51373913629632e-17!GO:0000313;organellar ribosome;1.51373913629632e-17!GO:0009057;macromolecule catabolic process;1.84427271722456e-17!GO:0044248;cellular catabolic process;2.09622343097837e-17!GO:0016604;nuclear body;2.59904726188951e-17!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.65097085487751e-17!GO:0008135;translation factor activity, nucleic acid binding;2.84525550884049e-17!GO:0000502;proteasome complex (sensu Eukaryota);3.63019140565692e-17!GO:0006605;protein targeting;5.14405800944504e-17!GO:0044453;nuclear membrane part;7.59885570063996e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.66322127360879e-16!GO:0050136;NADH dehydrogenase (quinone) activity;1.72041871992555e-16!GO:0003954;NADH dehydrogenase activity;1.72041871992555e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.72041871992555e-16!GO:0004386;helicase activity;1.91972818176537e-16!GO:0006511;ubiquitin-dependent protein catabolic process;2.84416923251656e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;2.95643661292541e-16!GO:0006399;tRNA metabolic process;3.2032973030255e-16!GO:0019941;modification-dependent protein catabolic process;3.48749063012587e-16!GO:0043632;modification-dependent macromolecule catabolic process;3.48749063012587e-16!GO:0044257;cellular protein catabolic process;7.31928919122441e-16!GO:0043412;biopolymer modification;1.07080634897174e-15!GO:0008134;transcription factor binding;2.03012914408449e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.2037531930672e-15!GO:0006364;rRNA processing;2.29209650997394e-15!GO:0012505;endomembrane system;2.64585936459286e-15!GO:0005635;nuclear envelope;3.51310043636567e-15!GO:0031965;nuclear membrane;3.54836555014331e-15!GO:0016072;rRNA metabolic process;3.92174796183377e-15!GO:0051186;cofactor metabolic process;6.54298931837684e-15!GO:0042775;organelle ATP synthesis coupled electron transport;8.56168990245889e-15!GO:0042773;ATP synthesis coupled electron transport;8.56168990245889e-15!GO:0050657;nucleic acid transport;8.94031897015817e-15!GO:0051236;establishment of RNA localization;8.94031897015817e-15!GO:0050658;RNA transport;8.94031897015817e-15!GO:0030964;NADH dehydrogenase complex (quinone);1.02843145632094e-14!GO:0045271;respiratory chain complex I;1.02843145632094e-14!GO:0005747;mitochondrial respiratory chain complex I;1.02843145632094e-14!GO:0006403;RNA localization;1.46366350685761e-14!GO:0008026;ATP-dependent helicase activity;1.71600065375991e-14!GO:0051726;regulation of cell cycle;2.63355494737906e-14!GO:0006413;translational initiation;3.28330567608614e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;3.60908732276822e-14!GO:0000074;regulation of progression through cell cycle;4.80151957532407e-14!GO:0016607;nuclear speck;4.8549445793763e-14!GO:0006913;nucleocytoplasmic transport;5.24470161816684e-14!GO:0005643;nuclear pore;5.77471033668486e-14!GO:0051169;nuclear transport;9.85087861201092e-14!GO:0048770;pigment granule;1.06067100317184e-13!GO:0042470;melanosome;1.06067100317184e-13!GO:0003743;translation initiation factor activity;1.1332456060395e-13!GO:0006446;regulation of translational initiation;1.62621414038051e-13!GO:0051082;unfolded protein binding;1.71278781007056e-13!GO:0030163;protein catabolic process;2.26295526036427e-13!GO:0000785;chromatin;2.82722953421132e-13!GO:0016568;chromatin modification;3.670033557212e-13!GO:0065002;intracellular protein transport across a membrane;5.38313181915038e-13!GO:0006464;protein modification process;7.33368648800549e-13!GO:0006732;coenzyme metabolic process;7.39764101180208e-13!GO:0012501;programmed cell death;1.29688545127658e-12!GO:0006915;apoptosis;1.42067943369193e-12!GO:0051028;mRNA transport;1.50196140901703e-12!GO:0006261;DNA-dependent DNA replication;3.33538495644312e-12!GO:0065004;protein-DNA complex assembly;4.13786084635445e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;4.26137539813533e-12!GO:0043687;post-translational protein modification;4.62407038273961e-12!GO:0044432;endoplasmic reticulum part;4.84484427849052e-12!GO:0046930;pore complex;5.12273725728287e-12!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;6.86120198811152e-12!GO:0006333;chromatin assembly or disassembly;7.47275299395675e-12!GO:0008219;cell death;9.48900897058735e-12!GO:0016265;death;9.48900897058735e-12!GO:0043566;structure-specific DNA binding;1.07300462287466e-11!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.41692930716748e-11!GO:0004812;aminoacyl-tRNA ligase activity;1.41692930716748e-11!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.41692930716748e-11!GO:0030532;small nuclear ribonucleoprotein complex;2.45520584842083e-11!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;3.23297169116376e-11!GO:0009259;ribonucleotide metabolic process;3.7117368020494e-11!GO:0043038;amino acid activation;3.85955920594547e-11!GO:0006418;tRNA aminoacylation for protein translation;3.85955920594547e-11!GO:0043039;tRNA aminoacylation;3.85955920594547e-11!GO:0003697;single-stranded DNA binding;7.66785619258228e-11!GO:0006163;purine nucleotide metabolic process;8.08924468645962e-11!GO:0017038;protein import;1.00018463860209e-10!GO:0009056;catabolic process;1.71078205982194e-10!GO:0006164;purine nucleotide biosynthetic process;2.4888307911837e-10!GO:0016779;nucleotidyltransferase activity;2.67606590942386e-10!GO:0008565;protein transporter activity;3.02267093536628e-10!GO:0000775;chromosome, pericentric region;3.22013944320429e-10!GO:0009260;ribonucleotide biosynthetic process;3.40980320396104e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;3.73400186683884e-10!GO:0005783;endoplasmic reticulum;5.02396111474949e-10!GO:0048193;Golgi vesicle transport;5.62730845267872e-10!GO:0009055;electron carrier activity;9.8862994725554e-10!GO:0003712;transcription cofactor activity;1.12328873251906e-09!GO:0009150;purine ribonucleotide metabolic process;1.16281328371442e-09!GO:0005819;spindle;1.34544083066203e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.82588899848369e-09!GO:0006366;transcription from RNA polymerase II promoter;2.46570760549016e-09!GO:0009152;purine ribonucleotide biosynthetic process;3.61138227140464e-09!GO:0003899;DNA-directed RNA polymerase activity;3.71745375991754e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;3.96724419089079e-09!GO:0016787;hydrolase activity;4.45399223575442e-09!GO:0019222;regulation of metabolic process;5.5421329937843e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;6.2578367192229e-09!GO:0005789;endoplasmic reticulum membrane;6.7864246727866e-09!GO:0050794;regulation of cellular process;6.99912235710906e-09!GO:0009060;aerobic respiration;7.39287781437286e-09!GO:0008639;small protein conjugating enzyme activity;8.17092517917384e-09!GO:0000075;cell cycle checkpoint;9.73769150755971e-09!GO:0019787;small conjugating protein ligase activity;1.31572263979879e-08!GO:0006461;protein complex assembly;1.31572263979879e-08!GO:0051246;regulation of protein metabolic process;1.57209318582633e-08!GO:0051188;cofactor biosynthetic process;2.01215851283087e-08!GO:0004842;ubiquitin-protein ligase activity;2.11473866898384e-08!GO:0015986;ATP synthesis coupled proton transport;2.82468723845153e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.82468723845153e-08!GO:0008094;DNA-dependent ATPase activity;2.87192939426777e-08!GO:0005657;replication fork;3.0243594601916e-08!GO:0016740;transferase activity;3.10655451735227e-08!GO:0019829;cation-transporting ATPase activity;4.18035958392133e-08!GO:0000245;spliceosome assembly;4.96425174704069e-08!GO:0045333;cellular respiration;5.74316536160911e-08!GO:0031497;chromatin assembly;6.29149038987145e-08!GO:0051329;interphase of mitotic cell cycle;6.65428190861497e-08!GO:0007005;mitochondrion organization and biogenesis;7.58562807324279e-08!GO:0005813;centrosome;7.85008640733255e-08!GO:0051325;interphase;8.60129876788786e-08!GO:0006099;tricarboxylic acid cycle;9.05375810910248e-08!GO:0046356;acetyl-CoA catabolic process;9.05375810910248e-08!GO:0006084;acetyl-CoA metabolic process;9.22339334782001e-08!GO:0031202;RNA splicing factor activity, transesterification mechanism;9.24259779315765e-08!GO:0009141;nucleoside triphosphate metabolic process;1.01248022390144e-07!GO:0009199;ribonucleoside triphosphate metabolic process;1.06902425353402e-07!GO:0006334;nucleosome assembly;1.07853871921367e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.10854841154605e-07!GO:0016881;acid-amino acid ligase activity;1.24647106753001e-07!GO:0005815;microtubule organizing center;1.28185623189805e-07!GO:0015630;microtubule cytoskeleton;1.49928801300764e-07!GO:0003724;RNA helicase activity;1.50763665155471e-07!GO:0031323;regulation of cellular metabolic process;1.51629429668798e-07!GO:0015078;hydrogen ion transmembrane transporter activity;1.69382663408839e-07!GO:0006310;DNA recombination;1.69382663408839e-07!GO:0046034;ATP metabolic process;1.77190890718266e-07!GO:0009142;nucleoside triphosphate biosynthetic process;1.97379316883668e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.97379316883668e-07!GO:0006793;phosphorus metabolic process;2.03951069351629e-07!GO:0006796;phosphate metabolic process;2.03951069351629e-07!GO:0006754;ATP biosynthetic process;2.26048563034988e-07!GO:0006753;nucleoside phosphate metabolic process;2.26048563034988e-07!GO:0005839;proteasome core complex (sensu Eukaryota);2.26150391564035e-07!GO:0016192;vesicle-mediated transport;2.34533621799529e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.36039494678028e-07!GO:0009144;purine nucleoside triphosphate metabolic process;2.36039494678028e-07!GO:0006302;double-strand break repair;2.49997834682547e-07!GO:0042981;regulation of apoptosis;2.56237828517446e-07!GO:0007051;spindle organization and biogenesis;2.99568579702358e-07!GO:0051170;nuclear import;3.05246709454128e-07!GO:0006401;RNA catabolic process;3.26566884579916e-07!GO:0043067;regulation of programmed cell death;3.44090979168845e-07!GO:0044452;nucleolar part;3.88582240048372e-07!GO:0003713;transcription coactivator activity;4.52580583396624e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;4.57076009813175e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;4.57076009813175e-07!GO:0016363;nuclear matrix;4.61517665253486e-07!GO:0006606;protein import into nucleus;4.64848485784359e-07!GO:0006752;group transfer coenzyme metabolic process;5.11619761418168e-07!GO:0009109;coenzyme catabolic process;5.80822632480392e-07!GO:0009108;coenzyme biosynthetic process;6.08773286511723e-07!GO:0032446;protein modification by small protein conjugation;6.24171877041132e-07!GO:0005794;Golgi apparatus;7.12746278662326e-07!GO:0016469;proton-transporting two-sector ATPase complex;7.81760537280857e-07!GO:0016310;phosphorylation;8.47818965665326e-07!GO:0007088;regulation of mitosis;8.96875221078545e-07!GO:0006950;response to stress;9.16589166354146e-07!GO:0004298;threonine endopeptidase activity;1.17816947426494e-06!GO:0048475;coated membrane;1.21572900954114e-06!GO:0030117;membrane coat;1.21572900954114e-06!GO:0003690;double-stranded DNA binding;1.24874576839617e-06!GO:0051168;nuclear export;1.3232250391609e-06!GO:0016567;protein ubiquitination;1.42769026206071e-06!GO:0005762;mitochondrial large ribosomal subunit;1.54362682772711e-06!GO:0000315;organellar large ribosomal subunit;1.54362682772711e-06!GO:0045259;proton-transporting ATP synthase complex;1.54811456400587e-06!GO:0008033;tRNA processing;1.604258668836e-06!GO:0009117;nucleotide metabolic process;2.16066813454076e-06!GO:0016741;transferase activity, transferring one-carbon groups;2.33206064554387e-06!GO:0003682;chromatin binding;2.49107430247097e-06!GO:0005667;transcription factor complex;2.63451761752209e-06!GO:0008168;methyltransferase activity;2.69229500308465e-06!GO:0006350;transcription;3.11532963466881e-06!GO:0043623;cellular protein complex assembly;3.30487862226597e-06!GO:0006888;ER to Golgi vesicle-mediated transport;3.34244280652157e-06!GO:0005768;endosome;5.62059551371138e-06!GO:0016563;transcription activator activity;5.72015616778085e-06!GO:0004518;nuclease activity;6.28986885468532e-06!GO:0051187;cofactor catabolic process;6.31447463719938e-06!GO:0006613;cotranslational protein targeting to membrane;6.67087784731105e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;6.6909195380961e-06!GO:0003678;DNA helicase activity;7.32155460358784e-06!GO:0004527;exonuclease activity;7.81931348185617e-06!GO:0007059;chromosome segregation;8.37579609720051e-06!GO:0010468;regulation of gene expression;1.11375882104715e-05!GO:0003684;damaged DNA binding;1.20171999096629e-05!GO:0005793;ER-Golgi intermediate compartment;1.2087294211129e-05!GO:0051427;hormone receptor binding;1.22024346861796e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.27098321105373e-05!GO:0050789;regulation of biological process;1.4238888530495e-05!GO:0000151;ubiquitin ligase complex;1.44172373682161e-05!GO:0008186;RNA-dependent ATPase activity;1.51681039070379e-05!GO:0006352;transcription initiation;1.56691781069989e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.7022545856647e-05!GO:0015399;primary active transmembrane transporter activity;1.7022545856647e-05!GO:0043021;ribonucleoprotein binding;1.78122078062318e-05!GO:0000314;organellar small ribosomal subunit;1.92293682337714e-05!GO:0005763;mitochondrial small ribosomal subunit;1.92293682337714e-05!GO:0007093;mitotic cell cycle checkpoint;2.23607780935208e-05!GO:0030120;vesicle coat;2.31317246610903e-05!GO:0030662;coated vesicle membrane;2.31317246610903e-05!GO:0000776;kinetochore;2.31317246610903e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;2.35724512871854e-05!GO:0051052;regulation of DNA metabolic process;2.41520267019176e-05!GO:0030880;RNA polymerase complex;2.59790731639684e-05!GO:0032508;DNA duplex unwinding;2.65058071857822e-05!GO:0032392;DNA geometric change;2.65058071857822e-05!GO:0035257;nuclear hormone receptor binding;2.66471116566466e-05!GO:0003729;mRNA binding;2.80012518723195e-05!GO:0043069;negative regulation of programmed cell death;2.93247708362763e-05!GO:0006626;protein targeting to mitochondrion;3.02194410415234e-05!GO:0003677;DNA binding;3.3798772229707e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;3.54203767165676e-05!GO:0043066;negative regulation of apoptosis;3.68638246411869e-05!GO:0065009;regulation of a molecular function;4.21887749586877e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;4.39270723879789e-05!GO:0006383;transcription from RNA polymerase III promoter;4.42443798411267e-05!GO:0006916;anti-apoptosis;4.50116317873123e-05!GO:0004004;ATP-dependent RNA helicase activity;4.88951226171963e-05!GO:0006417;regulation of translation;5.20195101311518e-05!GO:0006612;protein targeting to membrane;5.40674386039656e-05!GO:0006268;DNA unwinding during replication;5.77502436470023e-05!GO:0006091;generation of precursor metabolites and energy;6.26243775740275e-05!GO:0055029;nuclear DNA-directed RNA polymerase complex;6.65082240609561e-05!GO:0000428;DNA-directed RNA polymerase complex;6.65082240609561e-05!GO:0043681;protein import into mitochondrion;6.7984184337232e-05!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;6.81165042090097e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;7.28328780520737e-05!GO:0005773;vacuole;7.36781120178266e-05!GO:0031324;negative regulation of cellular metabolic process;8.16399739906769e-05!GO:0006414;translational elongation;8.43955272600559e-05!GO:0016853;isomerase activity;8.44696852617051e-05!GO:0006402;mRNA catabolic process;9.37338931052665e-05!GO:0048523;negative regulation of cellular process;9.48717582156201e-05!GO:0006405;RNA export from nucleus;9.5483586507264e-05!GO:0000323;lytic vacuole;9.93307126605681e-05!GO:0005764;lysosome;9.93307126605681e-05!GO:0000786;nucleosome;0.000104152139791903!GO:0045786;negative regulation of progression through cell cycle;0.000128373704400441!GO:0006839;mitochondrial transport;0.000130478986738523!GO:0016491;oxidoreductase activity;0.000153135751441336!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.000162494974084626!GO:0009165;nucleotide biosynthetic process;0.000168326072938675!GO:0005684;U2-dependent spliceosome;0.000175503977341521!GO:0031968;organelle outer membrane;0.000180718290328102!GO:0019899;enzyme binding;0.000191994346880666!GO:0000082;G1/S transition of mitotic cell cycle;0.00019344123634826!GO:0045454;cell redox homeostasis;0.000208498818154929!GO:0000049;tRNA binding;0.000210786871280095!GO:0019867;outer membrane;0.000216593128345358!GO:0005788;endoplasmic reticulum lumen;0.000223779761615919!GO:0000922;spindle pole;0.000244056243100151!GO:0015992;proton transport;0.000248440829649952!GO:0006818;hydrogen transport;0.000258624114946384!GO:0016251;general RNA polymerase II transcription factor activity;0.000261610935116849!GO:0005885;Arp2/3 protein complex;0.000269284392643196!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000281487329206149!GO:0047485;protein N-terminus binding;0.000315718500173898!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000317655934675838!GO:0032774;RNA biosynthetic process;0.000318908527900672!GO:0005798;Golgi-associated vesicle;0.000319543765618459!GO:0031326;regulation of cellular biosynthetic process;0.000338493426517751!GO:0007006;mitochondrial membrane organization and biogenesis;0.00035158286317099!GO:0005770;late endosome;0.000383717598602465!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000385516398645766!GO:0007052;mitotic spindle organization and biogenesis;0.000390447285764076!GO:0006520;amino acid metabolic process;0.000400776364809002!GO:0031072;heat shock protein binding;0.000412872802209481!GO:0031570;DNA integrity checkpoint;0.000422691431564462!GO:0008654;phospholipid biosynthetic process;0.000423288689327887!GO:0043492;ATPase activity, coupled to movement of substances;0.000426555477313749!GO:0006351;transcription, DNA-dependent;0.000435071038670466!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000522172940764838!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000533727383146837!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000537886262977453!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000564183973420735!GO:0006338;chromatin remodeling;0.000569248512704383!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000594467310449206!GO:0006289;nucleotide-excision repair;0.000601061623232119!GO:0006367;transcription initiation from RNA polymerase II promoter;0.000615408923059523!GO:0019752;carboxylic acid metabolic process;0.000631975106351036!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000681740601799018!GO:0006082;organic acid metabolic process;0.000700895042936726!GO:0006270;DNA replication initiation;0.000700895042936726!GO:0048519;negative regulation of biological process;0.000702640685914834!GO:0043596;nuclear replication fork;0.000719014598838525!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00072884405892837!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00072884405892837!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00072884405892837!GO:0005741;mitochondrial outer membrane;0.000747490818339443!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000760420997968804!GO:0006284;base-excision repair;0.00076995879453145!GO:0005876;spindle microtubule;0.000792184368137257!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.000804322612316843!GO:0005758;mitochondrial intermembrane space;0.000836555400312178!GO:0030384;phosphoinositide metabolic process;0.000881390284112269!GO:0009451;RNA modification;0.000903571169620913!GO:0042770;DNA damage response, signal transduction;0.000909933560678833!GO:0015631;tubulin binding;0.000910720986213978!GO:0000228;nuclear chromosome;0.000953417589735974!GO:0000059;protein import into nucleus, docking;0.000955115331933759!GO:0009112;nucleobase metabolic process;0.000985453865571294!GO:0005637;nuclear inner membrane;0.00105295063085912!GO:0008312;7S RNA binding;0.00106524842198477!GO:0000819;sister chromatid segregation;0.00112353054945962!GO:0004003;ATP-dependent DNA helicase activity;0.00119670849894808!GO:0048500;signal recognition particle;0.0012193619916395!GO:0009892;negative regulation of metabolic process;0.00127329163676527!GO:0031124;mRNA 3'-end processing;0.0012929985339597!GO:0000178;exosome (RNase complex);0.00131486027362699!GO:0019843;rRNA binding;0.00135684137456689!GO:0003711;transcription elongation regulator activity;0.00140017887689333!GO:0000725;recombinational repair;0.0014022089933858!GO:0000724;double-strand break repair via homologous recombination;0.0014022089933858!GO:0000070;mitotic sister chromatid segregation;0.00142514053986948!GO:0015980;energy derivation by oxidation of organic compounds;0.00143426045215368!GO:0051252;regulation of RNA metabolic process;0.00148840223816953!GO:0046474;glycerophospholipid biosynthetic process;0.00149528202707522!GO:0051539;4 iron, 4 sulfur cluster binding;0.00151419187774924!GO:0008632;apoptotic program;0.00153209814428143!GO:0046483;heterocycle metabolic process;0.00156902000849314!GO:0000287;magnesium ion binding;0.00156977824822879!GO:0051920;peroxiredoxin activity;0.00159639236075536!GO:0008276;protein methyltransferase activity;0.00159647535368552!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00162132006231389!GO:0000077;DNA damage checkpoint;0.00165374604515734!GO:0051087;chaperone binding;0.00168387121293603!GO:0030118;clathrin coat;0.00177793905736193!GO:0044431;Golgi apparatus part;0.00181183180969265!GO:0046489;phosphoinositide biosynthetic process;0.00182317957200629!GO:0045449;regulation of transcription;0.00183227625640416!GO:0009889;regulation of biosynthetic process;0.00184555922010596!GO:0003887;DNA-directed DNA polymerase activity;0.00184555922010596!GO:0009303;rRNA transcription;0.00184787914491027!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00186287321422587!GO:0007243;protein kinase cascade;0.00186581513595447!GO:0031970;organelle envelope lumen;0.00192836096023481!GO:0042393;histone binding;0.0019441815544558!GO:0009124;nucleoside monophosphate biosynthetic process;0.00203463658549806!GO:0009123;nucleoside monophosphate metabolic process;0.00203463658549806!GO:0008408;3'-5' exonuclease activity;0.00213215316021134!GO:0006144;purine base metabolic process;0.00218980068694076!GO:0032200;telomere organization and biogenesis;0.00230875214534846!GO:0000723;telomere maintenance;0.00230875214534846!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00241599518331407!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00241599518331407!GO:0042802;identical protein binding;0.00243962425555409!GO:0016564;transcription repressor activity;0.00259185568403929!GO:0005769;early endosome;0.0026058140567465!GO:0043601;nuclear replisome;0.00265435202717694!GO:0030894;replisome;0.00265435202717694!GO:0006595;polyamine metabolic process;0.00265461422466927!GO:0050790;regulation of catalytic activity;0.00270666589112877!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0028201857970434!GO:0045047;protein targeting to ER;0.0028201857970434!GO:0043284;biopolymer biosynthetic process;0.00287860749784204!GO:0051540;metal cluster binding;0.00301985784104937!GO:0051536;iron-sulfur cluster binding;0.00301985784104937!GO:0008022;protein C-terminus binding;0.00315529032871065!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00321485842553383!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00321485842553383!GO:0016481;negative regulation of transcription;0.00324226587887351!GO:0004674;protein serine/threonine kinase activity;0.00330511098419862!GO:0006650;glycerophospholipid metabolic process;0.00336670791492454!GO:0032259;methylation;0.00346377336253436!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00347643631820659!GO:0031123;RNA 3'-end processing;0.00361140815981028!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00361140815981028!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00364512843083675!GO:0008234;cysteine-type peptidase activity;0.00366755372818995!GO:0019783;small conjugating protein-specific protease activity;0.003797229335141!GO:0006611;protein export from nucleus;0.00379972108490082!GO:0008139;nuclear localization sequence binding;0.00395740394537695!GO:0005048;signal sequence binding;0.00397902889374282!GO:0051053;negative regulation of DNA metabolic process;0.00431866178721047!GO:0004843;ubiquitin-specific protease activity;0.00439084360290036!GO:0046966;thyroid hormone receptor binding;0.00445981857969722!GO:0000339;RNA cap binding;0.00445981857969722!GO:0016272;prefoldin complex;0.00450173655488495!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.0047889693149663!GO:0004540;ribonuclease activity;0.00483874425029527!GO:0006400;tRNA modification;0.00486405867378059!GO:0004532;exoribonuclease activity;0.0048878906450444!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0048878906450444!GO:0016407;acetyltransferase activity;0.00489976625367815!GO:0000096;sulfur amino acid metabolic process;0.0050247572427346!GO:0005669;transcription factor TFIID complex;0.00512594357833897!GO:0009161;ribonucleoside monophosphate metabolic process;0.00519062550601027!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.00519062550601027!GO:0000726;non-recombinational repair;0.00536218326658442!GO:0043065;positive regulation of apoptosis;0.00553945152761415!GO:0003702;RNA polymerase II transcription factor activity;0.0056293704407432!GO:0030658;transport vesicle membrane;0.00570391053531502!GO:0043414;biopolymer methylation;0.00570412095085297!GO:0006275;regulation of DNA replication;0.00572494637800591!GO:0046112;nucleobase biosynthetic process;0.00579194070169936!GO:0022890;inorganic cation transmembrane transporter activity;0.0058871189665382!GO:0030119;AP-type membrane coat adaptor complex;0.00592125813529073!GO:0016859;cis-trans isomerase activity;0.00598359356075944!GO:0003746;translation elongation factor activity;0.00604408967384713!GO:0006378;mRNA polyadenylation;0.00604417448400649!GO:0008652;amino acid biosynthetic process;0.00622235817101569!GO:0003714;transcription corepressor activity;0.00652493431085428!GO:0008047;enzyme activator activity;0.00661005219067447!GO:0043068;positive regulation of programmed cell death;0.00676172395566455!GO:0050662;coenzyme binding;0.0068240680584367!GO:0043488;regulation of mRNA stability;0.00691452690366822!GO:0043487;regulation of RNA stability;0.00691452690366822!GO:0046983;protein dimerization activity;0.00693229295844989!GO:0009116;nucleoside metabolic process;0.00696871626346347!GO:0065007;biological regulation;0.00728827897094511!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00728827897094511!GO:0015002;heme-copper terminal oxidase activity;0.00728827897094511!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00728827897094511!GO:0004129;cytochrome-c oxidase activity;0.00728827897094511!GO:0044440;endosomal part;0.0075348678094708!GO:0010008;endosome membrane;0.0075348678094708!GO:0022415;viral reproductive process;0.00762998627831408!GO:0040029;regulation of gene expression, epigenetic;0.00768887951301501!GO:0031577;spindle checkpoint;0.00789027543142748!GO:0005774;vacuolar membrane;0.00794329351619682!GO:0016584;nucleosome positioning;0.00794329351619682!GO:0030131;clathrin adaptor complex;0.00797191166439592!GO:0004221;ubiquitin thiolesterase activity;0.00803917888873721!GO:0030867;rough endoplasmic reticulum membrane;0.00811868067892651!GO:0006506;GPI anchor biosynthetic process;0.00813579387485723!GO:0048487;beta-tubulin binding;0.00826013038729353!GO:0046822;regulation of nucleocytoplasmic transport;0.00826965767181666!GO:0044262;cellular carbohydrate metabolic process;0.00866225925907362!GO:0007017;microtubule-based process;0.00876436717643475!GO:0006917;induction of apoptosis;0.00884556533059416!GO:0006406;mRNA export from nucleus;0.0088486197798569!GO:0005832;chaperonin-containing T-complex;0.00886997670216459!GO:0006891;intra-Golgi vesicle-mediated transport;0.00931486411734174!GO:0008017;microtubule binding;0.00933062034440995!GO:0044450;microtubule organizing center part;0.00933309129992989!GO:0006376;mRNA splice site selection;0.00944806571288621!GO:0000389;nuclear mRNA 3'-splice site recognition;0.00944806571288621!GO:0000152;nuclear ubiquitin ligase complex;0.00953999737445599!GO:0005663;DNA replication factor C complex;0.00966363785403147!GO:0035258;steroid hormone receptor binding;0.00979724353287333!GO:0000910;cytokinesis;0.00981993754273122!GO:0000118;histone deacetylase complex;0.00983902728102682!GO:0031647;regulation of protein stability;0.00999432376666298!GO:0043022;ribosome binding;0.0103529783181474!GO:0003725;double-stranded RNA binding;0.0108299490138123!GO:0000792;heterochromatin;0.0110666873486617!GO:0012502;induction of programmed cell death;0.0112001948987438!GO:0007050;cell cycle arrest;0.0112355037989156!GO:0007034;vacuolar transport;0.0115719930421793!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0116379247082447!GO:0008320;protein transmembrane transporter activity;0.0118961677288226!GO:0006505;GPI anchor metabolic process;0.0119797790249744!GO:0030660;Golgi-associated vesicle membrane;0.0122028787996802!GO:0030663;COPI coated vesicle membrane;0.0122959091904825!GO:0030126;COPI vesicle coat;0.0122959091904825!GO:0016197;endosome transport;0.0123603605980531!GO:0000209;protein polyubiquitination;0.0124814431625408!GO:0016790;thiolester hydrolase activity;0.0126416061346007!GO:0022884;macromolecule transmembrane transporter activity;0.013075300810679!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.013075300810679!GO:0051098;regulation of binding;0.0131089954007836!GO:0000139;Golgi membrane;0.0132540822664919!GO:0048522;positive regulation of cellular process;0.0133826516030062!GO:0043189;H4/H2A histone acetyltransferase complex;0.0134039941436332!GO:0000781;chromosome, telomeric region;0.0137596709287468!GO:0035267;NuA4 histone acetyltransferase complex;0.013987217308662!GO:0008180;signalosome;0.0141217543650987!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0141230753056388!GO:0015036;disulfide oxidoreductase activity;0.0141561152727123!GO:0006519;amino acid and derivative metabolic process;0.0144789106575715!GO:0030521;androgen receptor signaling pathway;0.0146139152701668!GO:0006730;one-carbon compound metabolic process;0.0147084105406112!GO:0044437;vacuolar part;0.0148863383254487!GO:0042054;histone methyltransferase activity;0.0149551991129443!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0152782585215153!GO:0007021;tubulin folding;0.0155293599240589!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0157764198177787!GO:0019206;nucleoside kinase activity;0.0160909006242747!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0162490328421382!GO:0051287;NAD binding;0.0162505563526989!GO:0046467;membrane lipid biosynthetic process;0.0171934357653945!GO:0005765;lysosomal membrane;0.0172118074233494!GO:0000018;regulation of DNA recombination;0.0172425949898213!GO:0000793;condensed chromosome;0.0172425949898213!GO:0005874;microtubule;0.0172809558452794!GO:0030134;ER to Golgi transport vesicle;0.0176925088613443!GO:0006355;regulation of transcription, DNA-dependent;0.0176934135787262!GO:0044454;nuclear chromosome part;0.0177592340454486!GO:0032940;secretion by cell;0.0178878986081416!GO:0032039;integrator complex;0.0178878986081416!GO:0005652;nuclear lamina;0.018617776092048!GO:0000123;histone acetyltransferase complex;0.0189716079686842!GO:0006497;protein amino acid lipidation;0.0190819863282657!GO:0051789;response to protein stimulus;0.0191026392000443!GO:0006986;response to unfolded protein;0.0191026392000443!GO:0007004;telomere maintenance via telomerase;0.0198955269856374!GO:0045947;negative regulation of translational initiation;0.0202792766778518!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0210607074939518!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0210607074939518!GO:0009126;purine nucleoside monophosphate metabolic process;0.0210607074939518!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0210607074939518!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0213292312817479!GO:0005680;anaphase-promoting complex;0.0213292312817479!GO:0008156;negative regulation of DNA replication;0.0214174778869222!GO:0031252;leading edge;0.0217105140259785!GO:0046426;negative regulation of JAK-STAT cascade;0.0221598600902824!GO:0006118;electron transport;0.0222605577277057!GO:0004523;ribonuclease H activity;0.0224059278855693!GO:0005525;GTP binding;0.0226601403145194!GO:0016279;protein-lysine N-methyltransferase activity;0.0226877682608005!GO:0018024;histone-lysine N-methyltransferase activity;0.0226877682608005!GO:0016278;lysine N-methyltransferase activity;0.0226877682608005!GO:0003924;GTPase activity;0.0229884227334062!GO:0048471;perinuclear region of cytoplasm;0.0233736616600026!GO:0008538;proteasome activator activity;0.023872592493325!GO:0001522;pseudouridine synthesis;0.0242163501140185!GO:0044438;microbody part;0.0242163501140185!GO:0044439;peroxisomal part;0.0242163501140185!GO:0005732;small nucleolar ribonucleoprotein complex;0.0242216903629445!GO:0009067;aspartate family amino acid biosynthetic process;0.0245738773321657!GO:0030518;steroid hormone receptor signaling pathway;0.0247419209735617!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0252183763576475!GO:0045039;protein import into mitochondrial inner membrane;0.0252183763576475!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0252279953076734!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0252279953076734!GO:0043631;RNA polyadenylation;0.0253221110755559!GO:0004576;oligosaccharyl transferase activity;0.0255539734929267!GO:0008250;oligosaccharyl transferase complex;0.0260085282134112!GO:0030127;COPII vesicle coat;0.0260085282134112!GO:0012507;ER to Golgi transport vesicle membrane;0.0260085282134112!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0260269233983133!GO:0000175;3'-5'-exoribonuclease activity;0.0262561665473383!GO:0030137;COPI-coated vesicle;0.0264633758075879!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0269449958806624!GO:0007259;JAK-STAT cascade;0.0272390150945715!GO:0009081;branched chain family amino acid metabolic process;0.0275095743849731!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0280294782487536!GO:0010257;NADH dehydrogenase complex assembly;0.0280294782487536!GO:0033108;mitochondrial respiratory chain complex assembly;0.0280294782487536!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0283228180579353!GO:0003709;RNA polymerase III transcription factor activity;0.0284493647825604!GO:0008629;induction of apoptosis by intracellular signals;0.0287267088053419!GO:0004448;isocitrate dehydrogenase activity;0.0289546633450908!GO:0009967;positive regulation of signal transduction;0.0292696957281297!GO:0006220;pyrimidine nucleotide metabolic process;0.0293142836651055!GO:0030132;clathrin coat of coated pit;0.0297188962299948!GO:0042809;vitamin D receptor binding;0.0303192429056769!GO:0031903;microbody membrane;0.0303452044171566!GO:0005778;peroxisomal membrane;0.0303452044171566!GO:0030508;thiol-disulfide exchange intermediate activity;0.0308185852738729!GO:0008170;N-methyltransferase activity;0.0311644051681402!GO:0005869;dynactin complex;0.0313854738308605!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.0313854738308605!GO:0008625;induction of apoptosis via death domain receptors;0.0316857899813434!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0318824911335937!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0318824911335937!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0318824911335937!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0322042710444483!GO:0032984;macromolecular complex disassembly;0.0323903783193576!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0324893946972665!GO:0019079;viral genome replication;0.0329754540636923!GO:0031982;vesicle;0.0330335484739585!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0331091676563267!GO:0016408;C-acyltransferase activity;0.0331999466793188!GO:0051656;establishment of organelle localization;0.033372253978168!GO:0045045;secretory pathway;0.0334031595436556!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0334031595436556!GO:0030133;transport vesicle;0.0334338961985194!GO:0006740;NADPH regeneration;0.0334338961985194!GO:0006098;pentose-phosphate shunt;0.0334338961985194!GO:0008097;5S rRNA binding;0.0335455731066028!GO:0033170;DNA-protein loading ATPase activity;0.0336139374155052!GO:0003689;DNA clamp loader activity;0.0336139374155052!GO:0006596;polyamine biosynthetic process;0.0342637653786288!GO:0046128;purine ribonucleoside metabolic process;0.0342970802488582!GO:0042278;purine nucleoside metabolic process;0.0342970802488582!GO:0045815;positive regulation of gene expression, epigenetic;0.0342970802488582!GO:0009113;purine base biosynthetic process;0.0353691741602989!GO:0000097;sulfur amino acid biosynthetic process;0.0363884476594659!GO:0006379;mRNA cleavage;0.0364598849241873!GO:0051297;centrosome organization and biogenesis;0.0365729973465954!GO:0031023;microtubule organizing center organization and biogenesis;0.0365729973465954!GO:0008144;drug binding;0.0371152563730224!GO:0005784;translocon complex;0.0371152563730224!GO:0031371;ubiquitin conjugating enzyme complex;0.0371152563730224!GO:0006303;double-strand break repair via nonhomologous end joining;0.0372750418199723!GO:0030041;actin filament polymerization;0.0379904265934651!GO:0030433;ER-associated protein catabolic process;0.0380067707761378!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0380067707761378!GO:0001824;blastocyst development;0.0385690889758413!GO:0000119;mediator complex;0.0387642440444711!GO:0051223;regulation of protein transport;0.0387937707469931!GO:0030176;integral to endoplasmic reticulum membrane;0.0389198999560462!GO:0004239;methionyl aminopeptidase activity;0.0395360501236573!GO:0050178;phenylpyruvate tautomerase activity;0.0397953954601092!GO:0008536;Ran GTPase binding;0.0401031470436689!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0406418081889802!GO:0031625;ubiquitin protein ligase binding;0.0406571518678939!GO:0005092;GDP-dissociation inhibitor activity;0.0409350919522043!GO:0006301;postreplication repair;0.0418077697545349!GO:0007096;regulation of exit from mitosis;0.041918288643764!GO:0010458;exit from mitosis;0.041918288643764!GO:0009066;aspartate family amino acid metabolic process;0.042132668904745!GO:0000303;response to superoxide;0.0421773822029233!GO:0022411;cellular component disassembly;0.0425314372524564!GO:0009304;tRNA transcription;0.0426702242611761!GO:0006555;methionine metabolic process;0.0427116520785236!GO:0003893;epsilon DNA polymerase activity;0.0429359599824719!GO:0032040;small subunit processome;0.0433855969904379!GO:0004177;aminopeptidase activity;0.0440795943073588!GO:0042158;lipoprotein biosynthetic process;0.0441272932352162!GO:0016569;covalent chromatin modification;0.0446962745899826!GO:0008610;lipid biosynthetic process;0.0448535767027759!GO:0005689;U12-dependent spliceosome;0.0448535767027759!GO:0003756;protein disulfide isomerase activity;0.0448535767027759!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0448535767027759!GO:0004659;prenyltransferase activity;0.0452854012580578!GO:0046365;monosaccharide catabolic process;0.0456746650889365!GO:0048037;cofactor binding;0.0456746650889365!GO:0006007;glucose catabolic process;0.0458249127807232!GO:0008143;poly(A) binding;0.0458890390103882!GO:0005658;alpha DNA polymerase:primase complex;0.0464597276269634!GO:0016180;snRNA processing;0.0465325382127814!GO:0016073;snRNA metabolic process;0.0465325382127814!GO:0042791;5S class rRNA transcription;0.0467182369405949!GO:0000127;transcription factor TFIIIC complex;0.0467182369405949!GO:0042797;tRNA transcription from RNA polymerase III promoter;0.0467182369405949!GO:0018196;peptidyl-asparagine modification;0.0467182369405949!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0467182369405949!GO:0016585;chromatin remodeling complex;0.0472535312507931!GO:0008624;induction of apoptosis by extracellular signals;0.0473039238670494!GO:0017134;fibroblast growth factor binding;0.0473413378544232!GO:0009615;response to virus;0.0478288284734312!GO:0008537;proteasome activator complex;0.0478288284734312!GO:0000930;gamma-tubulin complex;0.0485937071811474!GO:0004520;endodeoxyribonuclease activity;0.0487466562415829!GO:0033116;ER-Golgi intermediate compartment membrane;0.0494711322842364!GO:0051320;S phase;0.0496491340220264!GO:0006672;ceramide metabolic process;0.0499013806738829 | |||
|sample_id=10832 | |sample_id=10832 | ||
|sample_note= | |sample_note= | ||
| Line 76: | Line 99: | ||
|sample_tissue=blood | |sample_tissue=blood | ||
|top_motifs=MYB:2.48174527539;E2F1..5:1.87152685531;FOXD3:1.83303293813;YY1:1.71678035052;DMAP1_NCOR{1,2}_SMARC:1.56668120523;NKX2-2,8:1.42291291071;AIRE:1.37907773727;PITX1..3:1.31138572899;ZBTB16:1.28356989866;CDX1,2,4:1.18466461265;SPIB:1.12842943388;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.07551393864;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.06291122802;POU2F1..3:1.05823711614;SPI1:0.963842906596;RUNX1..3:0.946393178056;TOPORS:0.915354584669;IKZF2:0.89851781782;ELF1,2,4:0.8919502595;FOXP3:0.861037870554;ELK1,4_GABP{A,B1}:0.854423609232;NR5A1,2:0.826862764226;NFY{A,B,C}:0.798899482126;NRF1:0.777009354451;CUX2:0.764554485177;ZNF143:0.754681327546;HBP1_HMGB_SSRP1_UBTF:0.729015261743;BREu{core}:0.723886433116;AHR_ARNT_ARNT2:0.721671964374;FOXA2:0.702413378974;HAND1,2:0.69954671994;TEF:0.694697899247;PAX4:0.637258540002;OCT4_SOX2{dimer}:0.622293737553;FOXQ1:0.599779149351;NANOG{mouse}:0.53446936417;STAT1,3:0.517301785966;GFI1:0.512079361334;TLX2:0.502549461005;GATA4:0.502512244833;GATA6:0.499648648635;POU5F1:0.480619610568;FOX{I1,J2}:0.453673683452;ALX1:0.435363482514;NFIL3:0.4208074856;ETS1,2:0.410609519966;ZNF384:0.406046647235;HES1:0.403451797811;VSX1,2:0.389883337476;FOXP1:0.386371500605;NFE2L1:0.359678669544;MYOD1:0.357375675591;CRX:0.356315229024;PBX1:0.353215941438;KLF4:0.348351452863;NKX3-1:0.342871036696;RFX2..5_RFXANK_RFXAP:0.339123794814;POU1F1:0.318271791745;ARID5B:0.290047623723;RXRA_VDR{dimer}:0.275011084561;STAT5{A,B}:0.274367000516;CEBPA,B_DDIT3:0.273498741669;PAX8:0.264110748702;HSF1,2:0.250315533618;POU3F1..4:0.242004809448;SOX{8,9,10}:0.226790994224;EVI1:0.22613164519;ZNF238:0.206622536512;T:0.132215483732;DBP:0.130681929297;PAX6:0.0929291842584;PRDM1:0.0641779338654;AR:0.0522989218897;ATF5_CREB3:0.0459269603592;HOX{A4,D4}:0.0449425878319;NR6A1:0.0317031577339;NKX3-2:0.00299610700839;PDX1:-0.0255484197592;PAX5:-0.039728200674;bHLH_family:-0.0491865083226;BPTF:-0.0617898256551;GCM1,2:-0.0686610841302;EN1,2:-0.073141936302;HNF4A_NR2F1,2:-0.0751190332859;PAX3,7:-0.0961119293068;NANOG:-0.101933587833;HOX{A6,A7,B6,B7}:-0.108533701706;TFDP1:-0.120028478834;UFEwm:-0.133328112459;PRRX1,2:-0.144364016935;IRF1,2:-0.164945308258;ATF4:-0.16951155936;NFKB1_REL_RELA:-0.170481841039;FOXM1:-0.183974974589;NKX6-1,2:-0.192547411828;NFE2:-0.198608894428;SOX17:-0.225213963963;HNF1A:-0.23118167216;SRF:-0.23502770959;FOX{F1,F2,J1}:-0.269913413578;HOX{A5,B5}:-0.270488170738;NR1H4:-0.283937128214;ZEB1:-0.297717921479;HLF:-0.307889605291;RORA:-0.315634964086;IRF7:-0.318794929695;PAX2:-0.333953457905;CREB1:-0.347088603159;FOS_FOS{B,L1}_JUN{B,D}:-0.351681281199;TGIF1:-0.399436199214;POU6F1:-0.425679163421;ONECUT1,2:-0.42818200028;MEF2{A,B,C,D}:-0.432685498577;FOSL2:-0.439455990896;REST:-0.441374176881;NKX2-3_NKX2-5:-0.447488075841;STAT2,4,6:-0.462061809848;NHLH1,2:-0.465587533388;RXR{A,B,G}:-0.497022339681;PPARG:-0.497280621421;SNAI1..3:-0.505283646959;GZF1:-0.506631038437;MYBL2:-0.51085936523;ZNF423:-0.518305281769;LEF1_TCF7_TCF7L1,2:-0.519319780234;NFIX:-0.539337473587;ESR1:-0.576778599895;HOXA9_MEIS1:-0.579378188364;EP300:-0.588267081436;NFE2L2:-0.588542123157;BACH2:-0.600006696333;LMO2:-0.638474297966;GFI1B:-0.654622679639;MTF1:-0.691487090818;SREBF1,2:-0.694973564443;SOX5:-0.695960101034;FOXN1:-0.697169775671;ADNP_IRX_SIX_ZHX:-0.728004640236;SOX2:-0.730037499944;RFX1:-0.734159574364;TAL1_TCF{3,4,12}:-0.739339578375;FOXO1,3,4:-0.759033840858;ESRRA:-0.776268382714;NKX2-1,4:-0.794759772531;FOXL1:-0.795029369601;CDC5L:-0.802873408578;ZFP161:-0.817847427192;TP53:-0.828539120784;HMGA1,2:-0.837403688405;RREB1:-0.847451232812;MYFfamily:-0.859728001096;GTF2A1,2:-0.86623955074;LHX3,4:-0.880097269939;FOX{D1,D2}:-0.887408174891;TBP:-0.898470226652;ZNF148:-0.923466496303;MZF1:-0.953819947367;NFATC1..3:-0.986314106617;GTF2I:-0.989169323043;XBP1:-0.998005564035;HMX1:-1.02414377674;TFAP4:-1.02929874397;NR3C1:-1.04599726851;TFAP2{A,C}:-1.07778488054;IKZF1:-1.08089253295;PAX1,9:-1.09511448338;ALX4:-1.09889998339;ATF2:-1.10168268946;MED-1{core}:-1.12279920056;ZIC1..3:-1.16312975749;GLI1..3:-1.17760270036;ZBTB6:-1.19187429959;MTE{core}:-1.21266462121;RBPJ:-1.22027501229;TEAD1:-1.22781370963;SMAD1..7,9:-1.22868387562;HIC1:-1.27056844411;TLX1..3_NFIC{dimer}:-1.27790265618;EBF1:-1.30664913745;JUN:-1.3247457759;MAFB:-1.45828177243;SPZ1:-1.46807451575;HIF1A:-1.52753882272;XCPE1{core}:-1.53338889469;TFCP2:-1.58449758762;MAZ:-1.63497943399;PATZ1:-1.64845164435;TFAP2B:-1.7266739811;TBX4,5:-1.80596765155;ATF6:-1.82988586897;EGR1..3:-1.95074430959;SP1:-2.05423887676 | |top_motifs=MYB:2.48174527539;E2F1..5:1.87152685531;FOXD3:1.83303293813;YY1:1.71678035052;DMAP1_NCOR{1,2}_SMARC:1.56668120523;NKX2-2,8:1.42291291071;AIRE:1.37907773727;PITX1..3:1.31138572899;ZBTB16:1.28356989866;CDX1,2,4:1.18466461265;SPIB:1.12842943388;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.07551393864;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.06291122802;POU2F1..3:1.05823711614;SPI1:0.963842906596;RUNX1..3:0.946393178056;TOPORS:0.915354584669;IKZF2:0.89851781782;ELF1,2,4:0.8919502595;FOXP3:0.861037870554;ELK1,4_GABP{A,B1}:0.854423609232;NR5A1,2:0.826862764226;NFY{A,B,C}:0.798899482126;NRF1:0.777009354451;CUX2:0.764554485177;ZNF143:0.754681327546;HBP1_HMGB_SSRP1_UBTF:0.729015261743;BREu{core}:0.723886433116;AHR_ARNT_ARNT2:0.721671964374;FOXA2:0.702413378974;HAND1,2:0.69954671994;TEF:0.694697899247;PAX4:0.637258540002;OCT4_SOX2{dimer}:0.622293737553;FOXQ1:0.599779149351;NANOG{mouse}:0.53446936417;STAT1,3:0.517301785966;GFI1:0.512079361334;TLX2:0.502549461005;GATA4:0.502512244833;GATA6:0.499648648635;POU5F1:0.480619610568;FOX{I1,J2}:0.453673683452;ALX1:0.435363482514;NFIL3:0.4208074856;ETS1,2:0.410609519966;ZNF384:0.406046647235;HES1:0.403451797811;VSX1,2:0.389883337476;FOXP1:0.386371500605;NFE2L1:0.359678669544;MYOD1:0.357375675591;CRX:0.356315229024;PBX1:0.353215941438;KLF4:0.348351452863;NKX3-1:0.342871036696;RFX2..5_RFXANK_RFXAP:0.339123794814;POU1F1:0.318271791745;ARID5B:0.290047623723;RXRA_VDR{dimer}:0.275011084561;STAT5{A,B}:0.274367000516;CEBPA,B_DDIT3:0.273498741669;PAX8:0.264110748702;HSF1,2:0.250315533618;POU3F1..4:0.242004809448;SOX{8,9,10}:0.226790994224;EVI1:0.22613164519;ZNF238:0.206622536512;T:0.132215483732;DBP:0.130681929297;PAX6:0.0929291842584;PRDM1:0.0641779338654;AR:0.0522989218897;ATF5_CREB3:0.0459269603592;HOX{A4,D4}:0.0449425878319;NR6A1:0.0317031577339;NKX3-2:0.00299610700839;PDX1:-0.0255484197592;PAX5:-0.039728200674;bHLH_family:-0.0491865083226;BPTF:-0.0617898256551;GCM1,2:-0.0686610841302;EN1,2:-0.073141936302;HNF4A_NR2F1,2:-0.0751190332859;PAX3,7:-0.0961119293068;NANOG:-0.101933587833;HOX{A6,A7,B6,B7}:-0.108533701706;TFDP1:-0.120028478834;UFEwm:-0.133328112459;PRRX1,2:-0.144364016935;IRF1,2:-0.164945308258;ATF4:-0.16951155936;NFKB1_REL_RELA:-0.170481841039;FOXM1:-0.183974974589;NKX6-1,2:-0.192547411828;NFE2:-0.198608894428;SOX17:-0.225213963963;HNF1A:-0.23118167216;SRF:-0.23502770959;FOX{F1,F2,J1}:-0.269913413578;HOX{A5,B5}:-0.270488170738;NR1H4:-0.283937128214;ZEB1:-0.297717921479;HLF:-0.307889605291;RORA:-0.315634964086;IRF7:-0.318794929695;PAX2:-0.333953457905;CREB1:-0.347088603159;FOS_FOS{B,L1}_JUN{B,D}:-0.351681281199;TGIF1:-0.399436199214;POU6F1:-0.425679163421;ONECUT1,2:-0.42818200028;MEF2{A,B,C,D}:-0.432685498577;FOSL2:-0.439455990896;REST:-0.441374176881;NKX2-3_NKX2-5:-0.447488075841;STAT2,4,6:-0.462061809848;NHLH1,2:-0.465587533388;RXR{A,B,G}:-0.497022339681;PPARG:-0.497280621421;SNAI1..3:-0.505283646959;GZF1:-0.506631038437;MYBL2:-0.51085936523;ZNF423:-0.518305281769;LEF1_TCF7_TCF7L1,2:-0.519319780234;NFIX:-0.539337473587;ESR1:-0.576778599895;HOXA9_MEIS1:-0.579378188364;EP300:-0.588267081436;NFE2L2:-0.588542123157;BACH2:-0.600006696333;LMO2:-0.638474297966;GFI1B:-0.654622679639;MTF1:-0.691487090818;SREBF1,2:-0.694973564443;SOX5:-0.695960101034;FOXN1:-0.697169775671;ADNP_IRX_SIX_ZHX:-0.728004640236;SOX2:-0.730037499944;RFX1:-0.734159574364;TAL1_TCF{3,4,12}:-0.739339578375;FOXO1,3,4:-0.759033840858;ESRRA:-0.776268382714;NKX2-1,4:-0.794759772531;FOXL1:-0.795029369601;CDC5L:-0.802873408578;ZFP161:-0.817847427192;TP53:-0.828539120784;HMGA1,2:-0.837403688405;RREB1:-0.847451232812;MYFfamily:-0.859728001096;GTF2A1,2:-0.86623955074;LHX3,4:-0.880097269939;FOX{D1,D2}:-0.887408174891;TBP:-0.898470226652;ZNF148:-0.923466496303;MZF1:-0.953819947367;NFATC1..3:-0.986314106617;GTF2I:-0.989169323043;XBP1:-0.998005564035;HMX1:-1.02414377674;TFAP4:-1.02929874397;NR3C1:-1.04599726851;TFAP2{A,C}:-1.07778488054;IKZF1:-1.08089253295;PAX1,9:-1.09511448338;ALX4:-1.09889998339;ATF2:-1.10168268946;MED-1{core}:-1.12279920056;ZIC1..3:-1.16312975749;GLI1..3:-1.17760270036;ZBTB6:-1.19187429959;MTE{core}:-1.21266462121;RBPJ:-1.22027501229;TEAD1:-1.22781370963;SMAD1..7,9:-1.22868387562;HIC1:-1.27056844411;TLX1..3_NFIC{dimer}:-1.27790265618;EBF1:-1.30664913745;JUN:-1.3247457759;MAFB:-1.45828177243;SPZ1:-1.46807451575;HIF1A:-1.52753882272;XCPE1{core}:-1.53338889469;TFCP2:-1.58449758762;MAZ:-1.63497943399;PATZ1:-1.64845164435;TFAP2B:-1.7266739811;TBX4,5:-1.80596765155;ATF6:-1.82988586897;EGR1..3:-1.95074430959;SP1:-2.05423887676 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10832-111D4;search_select_hide=table117:FF:10832-111D4 | |||
}} | }} | ||
Latest revision as of 15:08, 3 June 2020
| Name: | acute myeloid leukemia (FAB M4eo) cell line:EoL-1 |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs13056 |
| Sample type: | cell lines |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
| Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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| CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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| Download raw sequence, BAM & CTSS | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13056
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13056
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.0177 |
| 10 | 10 | 0.0114 |
| 100 | 100 | 0.197 |
| 101 | 101 | 0.241 |
| 102 | 102 | 0.776 |
| 103 | 103 | 0.125 |
| 104 | 104 | 0.691 |
| 105 | 105 | 0.496 |
| 106 | 106 | 0.809 |
| 107 | 107 | 0.509 |
| 108 | 108 | 0.792 |
| 109 | 109 | 0.0448 |
| 11 | 11 | 0.0479 |
| 110 | 110 | 0.115 |
| 111 | 111 | 0.0813 |
| 112 | 112 | 0.458 |
| 113 | 113 | 0.804 |
| 114 | 114 | 0.0973 |
| 115 | 115 | 0.918 |
| 116 | 116 | 0.305 |
| 117 | 117 | 0.0389 |
| 118 | 118 | 0.0386 |
| 119 | 119 | 0.196 |
| 12 | 12 | 0.857 |
| 120 | 120 | 0.237 |
| 121 | 121 | 0.874 |
| 122 | 122 | 0.761 |
| 123 | 123 | 0.0104 |
| 124 | 124 | 0.242 |
| 125 | 125 | 0.467 |
| 126 | 126 | 0.182 |
| 127 | 127 | 0.106 |
| 128 | 128 | 0.827 |
| 129 | 129 | 0.352 |
| 13 | 13 | 0.0211 |
| 130 | 130 | 0.991 |
| 131 | 131 | 0.479 |
| 132 | 132 | 0.804 |
| 133 | 133 | 0.613 |
| 134 | 134 | 0.99 |
| 135 | 135 | 0.856 |
| 136 | 136 | 0.648 |
| 137 | 137 | 0.217 |
| 138 | 138 | 0.923 |
| 139 | 139 | 0.237 |
| 14 | 14 | 0.966 |
| 140 | 140 | 0.434 |
| 141 | 141 | 0.0612 |
| 142 | 142 | 0.417 |
| 143 | 143 | 0.547 |
| 144 | 144 | 0.603 |
| 145 | 145 | 0.722 |
| 146 | 146 | 0.893 |
| 147 | 147 | 0.281 |
| 148 | 148 | 0.0839 |
| 149 | 149 | 0.832 |
| 15 | 15 | 0.0882 |
| 150 | 150 | 0.632 |
| 151 | 151 | 0.793 |
| 152 | 152 | 0.124 |
| 153 | 153 | 0.968 |
| 154 | 154 | 0.811 |
| 155 | 155 | 0.0806 |
| 156 | 156 | 0.866 |
| 157 | 157 | 0.144 |
| 158 | 158 | 0.994 |
| 159 | 159 | 0.411 |
| 16 | 16 | 0.811 |
| 160 | 160 | 0.14 |
| 161 | 161 | 0.068 |
| 162 | 162 | 0.916 |
| 163 | 163 | 0.17 |
| 164 | 164 | 0.215 |
| 165 | 165 | 0.0735 |
| 166 | 166 | 0.518 |
| 167 | 167 | 0.101 |
| 168 | 168 | 0.976 |
| 169 | 169 | 0.227 |
| 17 | 17 | 0.648 |
| 18 | 18 | 0.506 |
| 19 | 19 | 0.575 |
| 2 | 2 | 0.521 |
| 20 | 20 | 0.373 |
| 21 | 21 | 0.0755 |
| 22 | 22 | 0.704 |
| 23 | 23 | 0.253 |
| 24 | 24 | 0.179 |
| 25 | 25 | 0.161 |
| 26 | 26 | 0.0568 |
| 27 | 27 | 0.609 |
| 28 | 28 | 0.843 |
| 29 | 29 | 0.0104 |
| 3 | 3 | 0.0286 |
| 30 | 30 | 0.0926 |
| 31 | 31 | 0.888 |
| 32 | 32 | 0.53 |
| 33 | 33 | 0.319 |
| 34 | 34 | 0.747 |
| 35 | 35 | 0.124 |
| 36 | 36 | 0.00894 |
| 37 | 37 | 0.296 |
| 38 | 38 | 0.337 |
| 39 | 39 | 0.586 |
| 4 | 4 | 0.224 |
| 40 | 40 | 0.203 |
| 41 | 41 | 0.738 |
| 42 | 42 | 0.13 |
| 43 | 43 | 0.405 |
| 44 | 44 | 0.0523 |
| 45 | 45 | 0.358 |
| 46 | 46 | 0.0514 |
| 47 | 47 | 0.0191 |
| 48 | 48 | 0.0424 |
| 49 | 49 | 0.158 |
| 5 | 5 | 0.511 |
| 50 | 50 | 0.849 |
| 51 | 51 | 0.663 |
| 52 | 52 | 0.301 |
| 53 | 53 | 0.509 |
| 54 | 54 | 0.726 |
| 55 | 55 | 0.795 |
| 56 | 56 | 0.95 |
| 57 | 57 | 0.0637 |
| 58 | 58 | 0.21 |
| 59 | 59 | 0.446 |
| 6 | 6 | 0.391 |
| 60 | 60 | 0.847 |
| 61 | 61 | 0.263 |
| 62 | 62 | 0.0788 |
| 63 | 63 | 0.355 |
| 64 | 64 | 0.145 |
| 65 | 65 | 0.877 |
| 66 | 66 | 0.159 |
| 67 | 67 | 0.646 |
| 68 | 68 | 0.818 |
| 69 | 69 | 0.213 |
| 7 | 7 | 0.155 |
| 70 | 70 | 0.381 |
| 71 | 71 | 0.0158 |
| 72 | 72 | 0.894 |
| 73 | 73 | 0.679 |
| 74 | 74 | 0.503 |
| 75 | 75 | 0.0265 |
| 76 | 76 | 0.261 |
| 77 | 77 | 0.864 |
| 78 | 78 | 0.0429 |
| 79 | 79 | 0.48 |
| 8 | 8 | 0.0723 |
| 80 | 80 | 0.469 |
| 81 | 81 | 0.166 |
| 82 | 82 | 0.464 |
| 83 | 83 | 0.464 |
| 84 | 84 | 0.673 |
| 85 | 85 | 0.524 |
| 86 | 86 | 0.633 |
| 87 | 87 | 0.451 |
| 88 | 88 | 0.941 |
| 89 | 89 | 0.954 |
| 9 | 9 | 0.669 |
| 90 | 90 | 0.024 |
| 91 | 91 | 0.393 |
| 92 | 92 | 0.36 |
| 93 | 93 | 0.934 |
| 94 | 94 | 0.237 |
| 95 | 95 | 0.0528 |
| 96 | 96 | 0.621 |
| 97 | 97 | 0.342 |
| 98 | 98 | 0.279 |
| 99 | 99 | 0.438 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13056
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101883 acute myeloid leukemia cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0101883 (acute myeloid leukemia cell line sample)
0100740 (myeloid leukemia cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
