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Coexpression cluster:C192

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Full id: C192_Neutrophils_CD14_Peripheral_Eosinophils_CD8_Natural_CD4



Phase1 CAGE Peaks

Hg19::chr10:125756841..125756870,-p@chr10:125756841..125756870
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Hg19::chr11:1882630..1882676,+p@chr11:1882630..1882676
+
Hg19::chr11:47377846..47377860,+p@chr11:47377846..47377860
+
Hg19::chr11:47378007..47378018,-p@chr11:47378007..47378018
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Hg19::chr11:47378052..47378069,-p@chr11:47378052..47378069
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Hg19::chr11:47378250..47378262,-p@chr11:47378250..47378262
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Hg19::chr11:47378382..47378395,-p@chr11:47378382..47378395
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Hg19::chr11:47378437..47378450,-p@chr11:47378437..47378450
-
Hg19::chr11:47378460..47378498,+p@chr11:47378460..47378498
+
Hg19::chr11:47378973..47378988,-p@chr11:47378973..47378988
-
Hg19::chr11:47378994..47379005,-p@chr11:47378994..47379005
-
Hg19::chr11:47379019..47379028,-p@chr11:47379019..47379028
-
Hg19::chr11:47379992..47380014,-p@chr11:47379992..47380014
-
Hg19::chr11:47402215..47402224,-p@chr11:47402215..47402224
-
Hg19::chr11:64628187..64628190,-p@chr11:64628187..64628190
-
Hg19::chr11:78112655..78112670,-p@chr11:78112655..78112670
-
Hg19::chr11:88071295..88071324,-p5@CTSC
Hg19::chr11:9268156..9268159,-p@chr11:9268156..9268159
-
Hg19::chr12:116614678..116614682,-p@chr12:116614678..116614682
-
Hg19::chr12:116645578..116645582,-p@chr12:116645578..116645582
-
Hg19::chr12:116687821..116687832,-p@chr12:116687821..116687832
-
Hg19::chr12:116712212..116712214,-p@chr12:116712212..116712214
-
Hg19::chr12:90068134..90068138,-p@chr12:90068134..90068138
-
Hg19::chr12:90098379..90098392,-p@chr12:90098379..90098392
-
Hg19::chr14:50684927..50684936,-p@chr14:50684927..50684936
-
Hg19::chr14:62177947..62177951,+p@chr14:62177947..62177951
+
Hg19::chr14:94858057..94858066,-p@chr14:94858057..94858066
-
Hg19::chr15:64985395..64985406,-p@chr15:64985395..64985406
-
Hg19::chr15:66684616..66684621,+p@chr15:66684616..66684621
+
Hg19::chr15:80355916..80355920,+p@chr15:80355916..80355920
+
Hg19::chr15:80408452..80408458,+p@chr15:80408452..80408458
+
Hg19::chr15:92411603..92411608,+p@chr15:92411603..92411608
+
Hg19::chr16:81507436..81507441,+p@chr16:81507436..81507441
+
Hg19::chr16:81569089..81569093,+p@chr16:81569089..81569093
+
Hg19::chr17:63033885..63033896,-p@chr17:63033885..63033896
-
Hg19::chr18:77682274..77682278,-p@chr18:77682274..77682278
-
Hg19::chr19:17200969..17200979,+p1@LOC100130442
Hg19::chr19:17225751..17225756,+p@chr19:17225751..17225756
+
Hg19::chr1:206868806..206868820,+p@chr1:206868806..206868820
+
Hg19::chr1:234743418..234743429,-p8@AK300375
Hg19::chr1:247581319..247581322,-p@chr1:247581319..247581322
-
Hg19::chr1:27961338..27961343,-p@chr1:27961338..27961343
-
Hg19::chr1:66805544..66805549,+p@chr1:66805544..66805549
+
Hg19::chr21:34778970..34778974,+p@chr21:34778970..34778974
+
Hg19::chr21:34800170..34800174,+p@chr21:34800170..34800174
+
Hg19::chr22:30280568..30280573,+p@chr22:30280568..30280573
+
Hg19::chr2:145240201..145240215,-p@chr2:145240201..145240215
-
Hg19::chr2:145263703..145263708,-p@chr2:145263703..145263708
-
Hg19::chr2:145267097..145267112,-p@chr2:145267097..145267112
-
Hg19::chr2:145267514..145267528,-p@chr2:145267514..145267528
-
Hg19::chr2:145272196..145272214,-p37@ZEB2
Hg19::chr2:145274038..145274052,-p31@ZEB2
Hg19::chr2:162007124..162007128,+p@chr2:162007124..162007128
+
Hg19::chr2:16829593..16829596,-p@chr2:16829593..16829596
-
Hg19::chr2:16845595..16845603,-p@chr2:16845595..16845603
-
Hg19::chr2:64328443..64328449,-p@chr2:64328443..64328449
-
Hg19::chr3:182626008..182626012,+p@chr3:182626008..182626012
+
Hg19::chr3:195096232..195096236,-p@chr3:195096232..195096236
-
Hg19::chr4:106122915..106122918,+p@chr4:106122915..106122918
+
Hg19::chr4:185727836..185727839,-p@chr4:185727836..185727839
-
Hg19::chr5:142166243..142166246,+p@chr5:142166243..142166246
+
Hg19::chr5:142172838..142172845,+p@chr5:142172838..142172845
+
Hg19::chr5:171535614..171535618,-p9@STK10
Hg19::chr5:60627654..60627666,-p@chr5:60627654..60627666
-
Hg19::chr5:74773469..74773473,-p@chr5:74773469..74773473
-
Hg19::chr5:94412147..94412155,-p@chr5:94412147..94412155
-
Hg19::chr6:108889433..108889437,+p@chr6:108889433..108889437
+
Hg19::chr6:108918111..108918115,+p@chr6:108918111..108918115
+
Hg19::chr6:14119946..14119985,+p@chr6:14119946..14119985
+
Hg19::chr6:15251164..15251175,+p@chr6:15251164..15251175
+
Hg19::chr6:15285357..15285361,+p@chr6:15285357..15285361
+
Hg19::chr6:15370582..15370586,+p@chr6:15370582..15370586
+
Hg19::chr6:15383546..15383559,+p@chr6:15383546..15383559
+
Hg19::chr6:15384618..15384622,+p@chr6:15384618..15384622
+
Hg19::chr6:15402150..15402158,+p@chr6:15402150..15402158
+
Hg19::chr6:163887231..163887256,+p@chr6:163887231..163887256
+
Hg19::chr6:18389053..18389064,+p@chr6:18389053..18389064
+
Hg19::chr6:37822761..37822764,+p@chr6:37822761..37822764
+
Hg19::chr6:37827971..37827975,+p@chr6:37827971..37827975
+
Hg19::chr7:90278480..90278521,+p@chr7:90278480..90278521
+
Hg19::chr7:99974408..99974412,+p@chr7:99974408..99974412
+
Hg19::chr8:131368773..131368783,-p@chr8:131368773..131368783
-
Hg19::chr8:56800071..56800080,+p@chr8:56800071..56800080
+
Hg19::chr8:56813118..56813123,+p@chr8:56813118..56813123
+
Hg19::chr9:33148794..33148803,-p@chr9:33148794..33148803
-
Hg19::chr9:95881097..95881117,-p@chr9:95881097..95881117
-
Hg19::chrX:19870749..19870754,-p@chrX:19870749..19870754
-
Hg19::chrX:44755886..44755889,+p@chrX:44755886..44755889
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0004214dipeptidyl-peptidase I activity0.0164248079072494
GO:0046332SMAD binding0.0389894005433572
GO:0008239dipeptidyl-peptidase activity0.0389894005433572
GO:0016806dipeptidyl-peptidase and tripeptidyl-peptidase activity0.0389894005433572



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
classical monocyte9.88e-6642
CD14-positive, CD16-negative classical monocyte9.88e-6642
myeloid leukocyte4.34e-6372
defensive cell4.00e-6148
phagocyte4.00e-6148
granulocyte monocyte progenitor cell5.51e-5567
myeloid lineage restricted progenitor cell9.74e-5466
macrophage dendritic cell progenitor6.62e-5361
monopoietic cell8.52e-5359
monocyte8.52e-5359
monoblast8.52e-5359
promonocyte8.52e-5359
leukocyte1.08e-52136
nongranular leukocyte1.50e-45115
myeloid cell1.98e-45108
common myeloid progenitor1.98e-45108
hematopoietic stem cell6.79e-45168
angioblastic mesenchymal cell6.79e-45168
hematopoietic lineage restricted progenitor cell7.24e-45120
hematopoietic oligopotent progenitor cell5.39e-43161
hematopoietic multipotent progenitor cell5.39e-43161
hematopoietic cell2.28e-41177
stuff accumulating cell7.10e-2787
intermediate monocyte4.81e-159
CD14-positive, CD16-positive monocyte4.81e-159
mesenchymal cell7.25e-10354
connective tissue cell2.76e-09361
granulocyte5.63e-088
motile cell2.73e-07386
Uber Anatomy
Ontology termp-valuen
hematopoietic system1.61e-5198
blood island1.61e-5198
bone marrow1.78e-4676
hemolymphoid system1.84e-46108
bone element1.69e-4382
immune system1.59e-4293
skeletal element4.05e-3890
skeletal system6.23e-34100
lateral plate mesoderm2.46e-17203
musculoskeletal system1.40e-14167
connective tissue1.68e-08371
adult organism9.93e-08114
neural nucleus5.87e-079
nucleus of brain5.87e-079
neural tube6.80e-0756
neural rod6.80e-0756
future spinal cord6.80e-0756
neural keel6.80e-0756
mesoderm8.59e-07315
mesoderm-derived structure8.59e-07315
presumptive mesoderm8.59e-07315
regional part of nervous system8.79e-0753
regional part of brain8.79e-0753


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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