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MCL coexpression mm9:1052

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:100215439..100215457,-p5@Hap1
Mm9::chr1:38851929..38851932,-p@chr1:38851929..38851932
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Mm9::chr1:84367076..84367079,-p@chr1:84367076..84367079
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Mm9::chr1:84577274..84577285,-p@chr1:84577274..84577285
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Mm9::chr5:38550223..38550234,-p@chr5:38550223..38550234
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Mm9::chr8:116813265..116813288,+p@chr8:116813265..116813288
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Mm9::chr8:61392493..61392501,+p@chr8:61392493..61392501
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0030503regulation of cell redox homeostasis0.0120518227025482
GO:0050780dopamine receptor binding0.0120518227025482
GO:0003906DNA-(apurinic or apyrimidinic site) lyase activity0.0140593041970687
GO:0007212dopamine receptor signaling pathway0.0271062004775957



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
central nervous system1.30e-3673
nervous system3.17e-3575
regional part of nervous system1.33e-3254
neurectoderm4.55e-3264
neural plate4.55e-3264
presumptive neural plate4.55e-3264
ectoderm-derived structure4.78e-3295
ectoderm4.78e-3295
presumptive ectoderm4.78e-3295
neural tube6.56e-3052
neural rod6.56e-3052
future spinal cord6.56e-3052
neural keel6.56e-3052
gray matter2.12e-2834
ecto-epithelium1.03e-2773
structure with developmental contribution from neural crest1.65e-2392
brain2.40e-2347
future brain2.40e-2347
regional part of brain2.00e-2246
brain grey matter1.20e-2129
regional part of telencephalon1.20e-2129
telencephalon1.20e-2129
pre-chordal neural plate8.45e-2149
anterior neural tube8.48e-2040
regional part of forebrain9.93e-1939
forebrain9.93e-1939
future forebrain9.93e-1939
cerebral cortex3.24e-1221
cerebral hemisphere3.24e-1221
pallium3.24e-1221
basal ganglion1.83e-118
nuclear complex of neuraxis1.83e-118
aggregate regional part of brain1.83e-118
collection of basal ganglia1.83e-118
cerebral subcortex1.83e-118
posterior neural tube9.24e-1112
chordal neural plate9.24e-1112
spinal cord2.31e-096
dorsal region element2.31e-096
dorsum2.31e-096
regional part of cerebral cortex8.70e-0917
regional part of spinal cord2.76e-085
gray matter of spinal cord2.76e-085
tube1.92e-07114
corpus striatum2.32e-075
striatum2.32e-075
ventral part of telencephalon2.32e-075
future corpus striatum2.32e-075
regional part of midbrain8.13e-074
midbrain8.13e-074
presumptive midbrain8.13e-074
midbrain neural tube8.13e-074
anatomical conduit8.38e-07122


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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