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Coexpression cluster:C1433: Difference between revisions

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{{Coexpression_clusters
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0160.1;0.600559,MA0161.1;0,MA0162.1;0.0383129,MA0163.1;0.0270301,MA0164.1;0.738243,MA0080.2;1.02158,MA0018.2;0.709805,MA0099.2;0.629739,MA0079.2;0.792956,MA0102.2;1.58513,MA0258.1;0.289793,MA0259.1;0.893594,MA0442.1;0}}
|full_id=C1433_Alveolar_Sebocyte_Keratinocyte_Corneal_Renal_Urothelial_Prostate
|id=C1433
|ontology_enrichment_celltype=CL:0000066!1.20e-44!254;CL:0002076!1.30e-13!43;CL:0000223!8.34e-13!59;CL:0002321!2.10e-10!248;CL:0000220!2.67e-10!246;CL:0000076!1.56e-09!62;CL:1000449!1.25e-07!16;CL:0000115!1.65e-07!35;CL:1000497!3.00e-07!18;CL:0002518!3.00e-07!18;CL:0002078!3.37e-07!44;CL:0002251!6.01e-07!21
|ontology_enrichment_disease=DOID:305!3.10e-13!106;DOID:0050687!6.19e-08!143
|ontology_enrichment_uberon=UBERON:0004119!3.66e-15!169;UBERON:0000925!3.66e-15!169;UBERON:0006595!3.66e-15!169;UBERON:0000468!1.68e-12!659;UBERON:0006554!6.42e-12!44;UBERON:0000477!1.26e-11!286;UBERON:0001007!3.33e-11!155;UBERON:0001555!3.33e-11!155;UBERON:0007026!3.33e-11!155;UBERON:0000922!3.68e-11!612;UBERON:0001008!4.44e-11!45;UBERON:0004921!6.91e-11!129;UBERON:0004185!6.91e-11!129;UBERON:0000467!1.60e-10!625;UBERON:0001004!2.79e-10!72;UBERON:0000480!2.95e-10!626;UBERON:0002050!4.44e-10!605;UBERON:0005423!4.44e-10!605;UBERON:0000923!7.62e-10!604;UBERON:0005291!7.62e-10!604;UBERON:0006598!7.62e-10!604;UBERON:0002532!7.62e-10!604;UBERON:0004111!2.36e-09!241;UBERON:0000077!6.30e-09!130;UBERON:0000481!1.09e-08!347;UBERON:0000062!1.65e-08!511;UBERON:0000065!1.65e-08!53;UBERON:0003914!1.73e-08!118;UBERON:0003064!1.96e-08!37;UBERON:0000064!2.11e-08!219;UBERON:0003103!4.39e-08!69;UBERON:0000080!6.69e-08!18;UBERON:0002120!6.69e-08!18;UBERON:0004875!6.69e-08!18;UBERON:0005721!6.69e-08!18;UBERON:0005754!6.69e-08!18;UBERON:0007297!6.69e-08!18;UBERON:0006555!7.73e-08!17;UBERON:0005103!7.73e-08!17;UBERON:0000083!7.73e-08!17;UBERON:0009201!7.73e-08!17;UBERON:0004819!7.73e-08!17;UBERON:0006553!7.73e-08!17;UBERON:0003074!7.73e-08!17;UBERON:0003060!7.73e-08!17;UBERON:0008947!1.11e-07!38;UBERON:0003258!1.11e-07!38;UBERON:0004211!1.25e-07!16;UBERON:0001285!1.25e-07!16;UBERON:0007684!1.25e-07!16;UBERON:0003220!1.25e-07!16;UBERON:0004208!1.25e-07!16;UBERON:0005911!2.08e-07!82;UBERON:0000119!2.12e-07!312;UBERON:0002113!3.03e-07!27;UBERON:0003918!3.03e-07!27;UBERON:0005095!3.03e-07!27;UBERON:0007687!3.03e-07!27;UBERON:0001048!3.12e-07!168;UBERON:0001041!3.13e-07!98;UBERON:0001737!3.25e-07!9;UBERON:0004876!3.62e-07!20;UBERON:0005177!3.84e-07!107;UBERON:0000483!3.87e-07!309;UBERON:0000161!5.91e-07!35;UBERON:0000072!7.67e-07!46;UBERON:0009569!8.10e-07!113;UBERON:0003104!8.27e-07!238;UBERON:0009142!8.27e-07!238;UBERON:0000489!8.75e-07!32;UBERON:0000058!8.77e-07!26
}}

Latest revision as of 11:44, 17 September 2013


Full id: C1433_Alveolar_Sebocyte_Keratinocyte_Corneal_Renal_Urothelial_Prostate



Phase1 CAGE Peaks

Hg19::chr17:39911483..39911514,-p@chr17:39911483..39911514
-
Hg19::chr17:39911596..39911611,-p@chr17:39911596..39911611
-
Hg19::chr17:39913783..39913800,-p@chr17:39913783..39913800
-
Hg19::chr17:39913926..39913939,-p@chr17:39913926..39913939
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Hg19::chr17:39919430..39919468,+p@chr17:39919430..39919468
+
Hg19::chr17:39921008..39921076,-p@chr17:39921008..39921076
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Uber Anatomy
Ontology termp-valuen
endoderm-derived structure3.01e-17160
endoderm3.01e-17160
presumptive endoderm3.01e-17160
anatomical cluster2.86e-16373
urinary system structure2.75e-1447
renal system2.04e-1348
subdivision of digestive tract5.03e-13118
digestive system5.39e-13145
digestive tract5.39e-13145
primitive gut5.39e-13145
multi-cellular organism1.81e-10656
respiratory system1.82e-1074
anatomical conduit1.87e-09240
foregut1.93e-0987
embryo2.19e-09592
developing anatomical structure3.02e-09581
organ part5.02e-09218
anatomical system7.95e-09624
multi-tissue structure8.38e-09342
respiratory tract9.76e-0954
anatomical group1.33e-08625
excretory tube1.61e-0816
kidney epithelium1.61e-0816
nephron epithelium2.39e-0815
renal tubule2.39e-0815
nephron tubule2.39e-0815
nephron2.39e-0815
uriniferous tubule2.39e-0815
nephrogenic mesenchyme2.39e-0815
organ5.00e-08503
respiratory primordium5.48e-0838
endoderm of foregut5.48e-0838
endo-epithelium1.52e-0782
kidney1.70e-0726
kidney mesenchyme1.70e-0726
upper urinary tract1.70e-0726
kidney rudiment1.70e-0726
kidney field1.70e-0726
compound organ1.92e-0768
parenchyma2.13e-0715
primordium2.39e-07160
larynx2.85e-079
epithelial tube2.92e-07117
trunk region element3.84e-07101
cell layer3.94e-07309
cortex of kidney4.04e-0712
renal parenchyma4.04e-0712
orifice4.18e-0736
subdivision of trunk4.35e-07112
cavitated compound organ5.99e-0731
segment of respiratory tract7.00e-0747
embryonic structure7.76e-07564
epithelium7.95e-07306
Disease
Ontology termp-valuen
carcinoma1.23e-13106
cell type cancer2.24e-08143


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.0799681
MA0004.10.558729
MA0006.11.01439
MA0007.10.539222
MA0009.11.03681
MA0014.10.262822
MA0017.10.432438
MA0019.10.7124
MA0024.10.929647
MA0025.11.17262
MA0027.12.65688
MA0028.10.408079
MA0029.10.949428
MA0030.10.937696
MA0031.10.871496
MA0038.10.665566
MA0040.10.955415
MA0041.10.578072
MA0042.10.544748
MA0043.11.03713
MA0046.11.02569
MA0048.10.464411
MA0050.10.545671
MA0051.10.661179
MA0052.10.959373
MA0055.10.213007
MA0056.10
MA0057.10.450439
MA0058.10.458909
MA0059.10.457555
MA0060.10.267412
MA0061.10.23892
MA0063.10
MA0066.12.69973
MA0067.11.35893
MA0068.10.199491
MA0069.11.02175
MA0070.11.01032
MA0071.10.625297
MA0072.11.00572
MA0073.10.347876
MA0074.10.660398
MA0076.10.475586
MA0077.10.997832
MA0078.10.763954
MA0081.10.457725
MA0083.11.04447
MA0084.11.5477
MA0087.11.00322
MA0088.10.32124
MA0089.10
MA0090.10.490736
MA0091.10.561458
MA0092.10.522012
MA0093.10.394379
MA0095.10
MA0098.10
MA0100.10.679972
MA0101.10.397846
MA0103.10.993014
MA0105.10.134725
MA0106.10.70837
MA0107.10.320267
MA0108.20.868347
MA0109.10
MA0111.10.504913
MA0113.10.725375
MA0114.10.314898
MA0115.11.28169
MA0116.10.323925
MA0117.11.07516
MA0119.10.440684
MA0122.11.10154
MA0124.11.23968
MA0125.11.15445
MA0130.10
MA0131.11.84113
MA0132.10
MA0133.10
MA0135.11.06778
MA0136.10.672893
MA0139.11.19942
MA0140.10.622527
MA0141.10.455728
MA0142.10.838805
MA0143.10.725558
MA0144.10.299851
MA0145.10.707171
MA0146.11.05598
MA0147.10.327615
MA0148.10.584698
MA0149.10.612449
MA0062.20.658749
MA0035.20.621793
MA0039.20.0313803
MA0138.20.765223
MA0002.20.255126
MA0137.20.414885
MA0104.20.735746
MA0047.20.695777
MA0112.20.680553
MA0065.22.35074
MA0150.10.484557
MA0151.10
MA0152.10.629368
MA0153.11.13732
MA0154.10.132326
MA0155.10.65596
MA0156.11.07131
MA0157.10.810597
MA0158.10
MA0159.12.38949
MA0160.10.600559
MA0161.10
MA0162.10.0383129
MA0163.10.0270301
MA0164.10.738243
MA0080.21.02158
MA0018.20.709805
MA0099.20.629739
MA0079.20.792956
MA0102.21.58513
MA0258.10.289793
MA0259.10.893594
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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