FF:10786-110H3: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004689 | ||
| | |accession_numbers=CAGE;DRX008022;DRR008894;DRZ000319;DRZ001704;DRZ011669;DRZ013054 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0000922,UBERON:0000473,UBERON:0000991,UBERON:0005156,UBERON:0000466,UBERON:0000062,UBERON:0004120,UBERON:0000061,UBERON:0000465,UBERON:0000990,UBERON:0002553,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0003135,UBERON:0003133,UBERON:0002323,UBERON:0000464,UBERON:0004458,UBERON:0010317,UBERON:0003101,UBERON:0000079 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0000255,CL:0000039,CL:0000586 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:14566,DOID:0050687,DOID:193,DOID:3095,DOID:305,DOID:2994 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100297,FF:0101120,FF:0101560 | |||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr8:145701192..145701241,-!p1@FOXH1!2.35!222.13!FOXH1;;chr20:31350184..31350200,+!p1@DNMT3B!2.34!437.33!DNMT3B;;chr10:135043702..135043729,+!p1@UTF1!2.30!197.55!UTF1;;chr4:188916918..188916942,+!p1@ZFP42!2.01!101.38!ZFP42;;chr3:181429704..181429722,+!p1@SOX2!1.98!94.75!SOX2;;chr19:22398550..22398579,-!p@chr19:22398550..22398579,-!1.98!93.73!ZNF676;;chr19:22469236..22469266,+!p1@ZNF729!1.97!92.40!ZNF729;;chr19:22193731..22193751,-!p1@ZNF208!1.96!90.87!ZNF208;;chr21:45681774..45681821,-!p1@DNMT3L!1.96!90.87!DNMT3L;;chr17:7493405..7493419,-!p1@SOX15!1.93!84.55!SOX15;;chr19:20278043..20278054,+!p2@ZNF486!1.91!80.47!ZNF486;;chr6:29648890..29648944,-!p1@ZFP57!1.89!76.19!ZFP57;;chr16:3149278..3149305,-!p1@ZSCAN10!1.86!72.21!ZSCAN10;;chr6:31138439..31138475,-!p1@POU5F1!1.86!71.39!POU5F1;;chr12:19556998..19557013,+!p6@AEBP2!1.82!64.97!AEBP2;;chr10:70320074..70320106,+!p1@TET1!1.77!113.62!TET1;;chr8:73921136..73921151,+!p2@TERF1!1.73!78.43!TERF1;;chr19:20188776..20188826,+!p1@ZNF90!1.72!132.89!ZNF90;;chr2:122042770..122042785,-!p1@TFCP2L1!1.72!51.20!TFCP2L1;;chr21:45681737..45681760,-!p2@DNMT3L!1.71!50.69!DNMT3L;;chr10:126138597..126138612,-!p1@NKX1-2!1.70!49.36!NKX1-2;;chr8:70983476..70983493,-!p1@PRDM14!1.68!46.81!PRDM14;;chrX:136648279..136648295,+!p1@ZIC3!1.68!46.71!ZIC3;;chr2:25475094..25475112,-!p3@DNMT3A!1.68!46.40!DNMT3A;;chr1:44584485..44584512,+!p2@KLF17!1.66!45.18!KLF17;;chr7:63505799..63505904,+!p1@ZNF727!1.63!41.41!ZNF727;;chr10:135043493..135043510,+!p2@UTF1!1.61!39.88!UTF1;;chr8:145701166..145701187,-!p2@FOXH1!1.60!38.96!FOXH1;;chr19:20278012..20278034,+!p1@ZNF486!1.58!299.34!ZNF486;;chr17:41622765..41622821,-!p2@ETV4!1.57!54.67!ETV4;;chr17:41622925..41622976,-!p3@ETV4!1.57!53.65!ETV4;;chr3:181429741..181429767,+!p2@SOX2!1.52!31.82!SOX2;;chr20:55204351..55204377,+!p1@TFAP2C!1.50!39.06!TFAP2C;;chr17:46622205..46622218,-!p3@HOXB2!1.50!34.88!HOXB2;;chr20:55205825..55205847,+!p2@TFAP2C!1.50!30.80!TFAP2C;;chr9:127358120..127358170,-!p3@NR6A1!1.50!30.60!NR6A1;;chr8:37963466..37963506,+!p3@ASH2L!1.49!37.43!ASH2L;;chr17:41622834..41622883,-!p6@ETV4!1.47!33.96!ETV4;;chr1:164528687..164528711,+!p6@PBX1!1.46!32.64!PBX1;;chr2:88752207..88752218,-!p1@FOXI3!1.44!26.42!FOXI3;;chrX:136648643..136648711,+!p2@ZIC3!1.43!25.91!ZIC3;;chr19:22605097..22605121,-!p2@ZNF98!1.43!25.70!ZNF98;;chr12:7941989..7942014,+!p1@NANOG!1.42!25.40!NANOG;;chr19:57352087..57352102,-!p1@PEG3,p1@ZIM2!1.41!24.89!PEG3;;chr7:57509877..57509895,+!p1@ZNF716!1.41!24.89!ZNF716;;chr19:12163769..12163798,-!p1@ZNF878!1.40!30.90!ZNF878;;chr10:135051353..135051367,+!p1@VENTX!1.40!24.17!VENTX;;chr2:25475120..25475176,-!p2@DNMT3A!1.39!31.82!DNMT3A;;chr8:70983443..70983460,-!p2@PRDM14!1.38!23.15!PRDM14;;chr2:16080659..16080685,+!p1@MYCN!1.37!22.64!MYCN;;chr9:114287433..114287513,+!p1@ZNF483!1.36!55.99!ZNF483;;chr5:149546334..149546364,+!p1@CDX1!1.35!21.42!CDX1;;chr19:22235279..22235301,+!p1@ZNF257!1.33!37.74!ZNF257;;chr20:50418972..50419029,-!p1@SALL4!1.33!20.50!SALL4;;chr19:20188831..20188844,+!p2@ZNF90!1.32!19.79!ZNF90;;chr20:20348740..20348757,+!p1@INSM1!1.32!19.68!INSM1;;chr19:22469215..22469229,+!p2@ZNF729!1.31!19.48!ZNF729;;chr1:6304233..6304243,+!p1@HES3!1.30!18.77!HES3;;chr7:14028743..14028799,-!p3@ETV1!1.29!23.25!ETV1;;chr4:299227..299272,-!p1@ZNF732!1.28!17.95!ZNF732;;chr20:42295745..42295765,+!p1@MYBL2!1.27!281.49!MYBL2;;chr7:20826504..20826526,-!p1@SP8!1.27!17.75!SP8;;chrX:139587228..139587234,-!p1@SOX3!1.27!17.54!SOX3;;chr19:22817119..22817145,+!p1@ZNF492!1.26!28.66!ZNF492;;chr12:19556960..19556982,+!p10@AEBP2!1.26!17.24!AEBP2;;chrX:136648297..136648319,+!p3@ZIC3!1.26!17.03!ZIC3;;chr6:15246200..15246214,+!p2@JARID2!1.25!46.20!JARID2;;chr20:55205791..55205817,+!p3@TFAP2C!1.25!16.83!TFAP2C;;chr14:57272369..57272391,-!p2@OTX2!1.25!16.62!OTX2;;chr3:185797712..185797746,-!p6@ETV5!1.24!16.42!ETV5;;chr5:2751762..2751784,-!p1@IRX2!1.24!16.32!IRX2;;chr12:3068544..3068597,+!p1@TEAD4!1.23!94.65!TEAD4;;chr1:201979703..201979721,+!p2@ELF3!1.23!16.11!ELF3;;chr19:22605136..22605154,-!p1@ZNF98!1.23!15.91!ZNF98;;chr1:247171316..247171336,-!p3@ZNF695!1.22!23.25!ZNF695;;chr1:63788229..63788250,+!p1@FOXD3!1.22!15.60!FOXD3;;chr20:50419055..50419066,-!p3@SALL4!1.21!15.20!SALL4;;chr19:9609272..9609297,-!p1@ZNF560!1.19!14.58!ZNF560;;chr1:40367668..40367684,-!p2@MYCL1!1.18!14.07!MYCL1;;chr19:20011775..20011800,+!p2@ZNF93!1.17!24.48!ZNF93;;chr1:6479968..6479986,-!p1@HES2!1.17!13.67!HES2;;chr19:22193706..22193717,-!p2@ZNF208!1.16!13.56!ZNF208;;chr19:20150268..20150298,-!p2@ZNF682!1.15!24.58!ZNF682;;chr1:247171347..247171366,-!p2@ZNF695!1.15!23.76!ZNF695;;chr19:21950332..21950356,-!p2@ZNF100!1.14!26.93!ZNF100;;chr2:16081912..16081931,+!p2@MYCN!1.13!12.54!MYCN;;chr8:37963407..37963454,+!p2@ASH2L!1.12!36.41!ASH2L;;chr17:41622731..41622764,-!p5@ETV4!1.12!12.24!ETV4;;chr1:44584568..44584585,+!p3@KLF17!1.12!12.24!KLF17;;chr6:15246261..15246312,+!p1@JARID2!1.10!278.43!JARID2;;chr19:23433144..23433204,-!p1@ZNF724P!1.10!51.91!ZNF724P;;chr15:74833584..74833626,+!p1@ARID3B!1.10!27.43!ARID3B;;chr20:42295713..42295738,+!p2@MYBL2!1.08!66.29!MYBL2;;chr1:201979743..201979762,+!p1@ELF3!1.08!11.12!ELF3;;chr9:96717629..96717644,-!p1@BARX1!1.08!10.91!BARX1;;chr6:43337180..43337244,-!p1@ZNF318!1.06!40.59!ZNF318;;chr17:41623009..41623053,-!p4@ETV4!1.06!17.03!ETV4;;chr17:46608354..46608385,-!p1@HOXB1!1.05!10.20!HOXB1;;chr11:63684602..63684664,-!p1@RCOR2!1.03!19.38!RCOR2;;chr19:20011744..20011770,+!p1@ZNF93!1.02!37.33!ZNF93;;chr19:22398533..22398542,-!p@chr19:22398533..22398542,-!1.02!9.48!ZNF676;;chr5:172662197..172662216,-!p1@NKX2-5!1.02!9.48!NKX2-5;;chr19:52932395..52932413,+!p1@ZNF534!1.02!9.38!ZNF534;;chr19:23869970..23869991,-!p1@ZNF675!1.01!35.59!ZNF675;;chr10:135044123..135044144,+!p5@UTF1!1.01!9.28!UTF1;;chr10:70320041..70320065,+!p2@TET1!1.01!9.28!TET1;;chr19:52932444..52932455,+!p2@ZNF534!1.00!9.08!ZNF534;;chr17:41623692..41623715,-!p1@ETV4!0.99!38.35!ETV4;;chr19:22966893..22966924,-!p2@ZNF99!0.99!8.87!ZNF99;;chr12:3068634..3068656,+!p5@TEAD4!0.99!8.77!TEAD4;;chr3:48282587..48282603,+!p1@ZNF589!0.98!39.27!ZNF589;;chr19:53289995..53290050,-!p1@ZNF600!0.98!36.21!ZNF600;;chr7:64023410..64023428,-!p2@ZNF680!0.98!13.67!ZNF680;;chr22:19748231..19748317,+!p1@TBX1!0.96!8.16!TBX1;;chr10:70320115..70320126,+!p3@TET1!0.96!8.16!TET1;;chr17:46132044..46132080,+!p4@NFE2L1!0.96!8.06!NFE2L1;;chr19:45579725..45579743,-!p1@ZNF296!0.95!36.72!ZNF296;;chr7:64254834..64254854,+!p2@ZNF138!0.95!14.69!ZNF138;;chr6:15246217..15246228,+!p3@JARID2!0.95!14.38!JARID2;;chr1:209979467..209979494,-!p1@IRF6!0.94!8.67!IRF6;;chr8:70983506..70983522,-!p3@PRDM14!0.94!7.65!PRDM14;;chr6:34204672..34204692,+!p1@HMGA1!0.93!871.60!HMGA1;;chr9:132427972..132428056,+!p1@PRRX2!0.93!9.89!PRRX2;;chr10:126138622..126138638,-!p2@NKX1-2!0.93!7.55!NKX1-2;;chr3:57234000..57234014,-!p1@HESX1!0.93!7.45!HESX1;;chr8:86089627..86089653,+!p3@E2F5!0.92!8.26!E2F5;;chr7:14028488..14028516,-!p2@ETV1!0.92!8.06!ETV1;;chr7:20826426..20826432,-!p2@SP8!0.92!7.34!SP8;;chr2:237077022..237077038,-!p1@GBX2!0.92!7.34!GBX2;;chr19:22966925..22966958,-!p1@ZNF99!0.92!7.24!ZNF99;;chr12:80084167..80084197,-!p5@PAWR!0.91!17.13!PAWR;;chr19:23299814..23299844,+!p1@ZNF730!0.91!8.87!ZNF730;;chr15:85147079..85147099,+!p4@ZSCAN2!0.91!7.04!ZSCAN2;;chr19:23941647..23941672,-!p2@ZNF681!0.90!11.83!ZNF681;;chr19:47523058..47523114,+!p1@NPAS1!0.90!6.94!NPAS1;;chr4:26322267..26322334,+!p3@RBPJ!0.89!16.83!RBPJ;;chr12:80084137..80084165,-!p10@PAWR!0.88!8.57!PAWR;;chr1:52902618..52902666,-!p11@ZCCHC11!0.88!6.63!ZCCHC11;;chr7:57509910..57509917,+!p2@ZNF716!0.88!6.63!ZNF716;;chr8:128428066..128428078,+!p1@POU5F1B!0.88!6.53!POU5F1B;;chr3:121286771..121286805,+!p1@ARGFX!0.88!6.53!ARGFX;;chr17:41622982..41623001,-!p11@ETV4!0.87!6.43!ETV4;;chr14:21994337..21994442,-!p1@SALL2!0.86!18.05!SALL2;;chr4:206390..206444,+!p1@ZNF876P!0.86!11.42!ZNF876P;;chr8:73921067..73921078,+!p3@TERF1!0.86!10.10!TERF1;;chr17:46622229..46622257,-!p6@HOXB2!0.86!7.34!HOXB2;;chr16:3149266..3149277,-!p2@ZSCAN10!0.86!6.32!ZSCAN10;;chr2:237076992..237077008,-!p2@GBX2!0.86!6.32!GBX2;;chr2:88752231..88752245,-!p2@FOXI3!0.86!6.32!FOXI3;;chr8:102504651..102504683,+!p1@GRHL2!0.86!6.22!GRHL2;;chr10:135043690..135043701,+!p4@UTF1!0.86!6.22!UTF1;;chr2:42795745..42795824,+!p1@MTA3!0.85!59.36!MTA3;;chr12:19592405..19592492,+!p2@AEBP2!0.85!55.07!AEBP2;;chr14:55493763..55493824,-!p1@WDHD1!0.85!48.24!WDHD1;;chr12:7079780..7079791,-!p2@PHB2!0.85!34.06!PHB2;;chr1:47779762..47779827,-!p1@STIL,p1@TAL1!0.85!29.58!TAL1;;chr19:20959098..20959117,+!p1@ZNF66P!0.85!26.82!ZNF66P;;chr17:41623667..41623682,-!p8@ETV4!0.85!6.63!ETV4;;chr21:45705752..45705767,+!p1@AIRE!0.85!6.02!AIRE;;chr12:6798692..6798723,-!p5@ZNF384!0.84!10.10!ZNF384;;chr3:71355163..71355209,-!p5@FOXP1!0.84!8.47!FOXP1;;chr19:52956798..52956843,+!p1@ZNF578!0.83!12.03!ZNF578;;chr1:40367530..40367597,-!p1@MYCL1!0.83!10.91!MYCL1;;chr12:6798731..6798751,-!p4@ZNF384!0.83!9.08!ZNF384;;chr9:132427883..132427951,+!p2@PRRX2!0.83!5.71!PRRX2;;chr1:204042233..204042249,+!p1@SOX13!0.82!38.25!SOX13;;chr12:3069037..3069119,+!p2@TEAD4!0.82!20.81!TEAD4;;chr21:45681768..45681773,-!p4@DNMT3L!0.82!5.61!DNMT3L;;chr19:19976683..19976709,+!p1@ZNF253!0.81!25.70!ZNF253;;chr19:12203100..12203132,+!p1@ZNF788!0.81!11.52!ZNF788;;chr11:65554528..65554546,+!p1@OVOL1!0.81!5.51!OVOL1;;chr8:86089417..86089440,+!p2@E2F5!0.80!11.01!E2F5;;chr7:28725715..28725727,+!p3@CREB5!0.80!6.43!CREB5;;chr10:8096772..8096787,+!p2@GATA3!0.80!6.32!GATA3;;chr14:22005197..22005261,-!p3@SALL2!0.80!5.30!SALL2;;chr19:23299851..23299880,+!p2@ZNF730!0.80!5.30!ZNF730;;chr10:97889464..97889494,+!p3@ZNF518A!0.79!10.10!ZNF518A;;chr15:74833547..74833567,+!p2@ARID3B!0.79!7.45!ARID3B;;chr10:48355030..48355090,+!p1@ZNF488!0.79!6.83!ZNF488;;chr19:38720294..38720348,-!p1@DPF1!0.79!6.53!DPF1;;chr1:40367692..40367703,-!p3@MYCL1!0.79!5.20!MYCL1;;chr12:54694653..54694672,-!p2@NFE2!0.79!5.20!NFE2;;chr19:21264991..21265026,+!p1@ZNF714!0.78!35.90!ZNF714;;chr7:148844205..148844236,+!p5@ZNF398!0.78!6.22!ZNF398;;chr8:144512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| |||
|ffid_belonging_in_development=UBERON:0009117,UBERON:0002532,UBERON:0006603,UBERON:0005564,UBERON:0010316 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|fonse_cell_line=FF:0101120,FF:0101560 | |fonse_cell_line=FF:0101120,FF:0101560 | ||
|fonse_cell_line_closure=FF:0101120,FF:0101560 | |fonse_cell_line_closure=FF:0101120,FF:0101560 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=CL:0000586;;DOID:3095;;EFO:0002091 | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/testicular%2520germ%2520cell%2520embryonal%2520carcinoma%2520cell%2520line%253aITO-II.CNhs11876.10786-110H3.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/testicular%2520germ%2520cell%2520embryonal%2520carcinoma%2520cell%2520line%253aITO-II.CNhs11876.10786-110H3.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/testicular%2520germ%2520cell%2520embryonal%2520carcinoma%2520cell%2520line%253aITO-II.CNhs11876.10786-110H3.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/testicular%2520germ%2520cell%2520embryonal%2520carcinoma%2520cell%2520line%253aITO-II.CNhs11876.10786-110H3.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/testicular%2520germ%2520cell%2520embryonal%2520carcinoma%2520cell%2520line%253aITO-II.CNhs11876.10786-110H3.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10786-110H3 | |||
|is_a=CL:0000586;;DOID:3095;;EFO:0002091;;FF:0000210;;FF:0100297;;FF:0101560;;UBERON:0000922 | |||
|is_obsolete= | |||
|library_id=CNhs11876 | |||
|library_id_phase_based=2:CNhs11876 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10786 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10786 | |||
|name=testicular germ cell embryonal carcinoma cell line:ITO-II | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11876,LSID830,release010,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0.0210885961662291,0,0,-0.160318030086386,0.115932033194051,0.00799254040694392,0.0535754295281297,0,0,0,0,0,0,0,0,0.259094472815984,0,0.207346980587175,0,0,-0.00473413752640617,0,0,0,0,0,0.161136576547927,0,0,0.101034415063548,0,0,0,0,0,0,0,0,0,0,0,0,-0.0173963247477385,0.0421771923324582,0,0,0,0,0,0,0,0.408138612330792,0,0,0,0,0,0,0.0421771923324582,0.229727870094329,0,0,0.287877082073502,0,0,0,0,0.207346980587175,0,0,0,0.0806184284061465,0,0,0,0,0.0421771923324582,0,0,0,0,0.0210885961662291,0,0,0,0,0.0331284009632625,0.0666942918456036,0,0.747372753686152,0,0.213973157599463,-0.190108806529639,0,0,0,0,0.0809255322437486,-0.0086875448570945,0,0,0,0.482841666768749,0,0,0,0,0,0,0.491330476711065,0,0,0,0,0,0,0.0962367607208385,0.148588872822021,0,0,-0.062557317541557,-0.229733922872795,0,0,0.0435352638121096,0,0,0 | |||
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| |||
|rna_box=110 | |||
|rna_catalog_number= | |||
|rna_concentration=1.20827 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.1 | |||
|rna_od260/280=2.04 | |||
|rna_position=H3 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=110H3 | |||
|rna_weight_ug=32.62329 | |||
|sample_age=unknown | |||
|sample_category=cell lines | |||
|sample_cell_catalog=jcrb0613 | |||
|sample_cell_line=ITO-II | |||
|sample_cell_lot= | |||
|sample_cell_type=unclassifiable | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=JAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=testicular germ cell embryonal carcinoma | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;4.8001985947893e-285!GO:0043226;organelle;2.62906325153412e-241!GO:0043229;intracellular organelle;6.12895607490871e-241!GO:0043231;intracellular membrane-bound organelle;2.48551766535701e-233!GO:0043227;membrane-bound organelle;3.66403092933134e-233!GO:0005737;cytoplasm;9.17667147118397e-182!GO:0044422;organelle part;6.00844661256755e-162!GO:0044446;intracellular organelle part;2.04958184000106e-160!GO:0044444;cytoplasmic part;4.04805177393086e-122!GO:0005634;nucleus;7.84134264928312e-113!GO:0032991;macromolecular complex;2.41782737494885e-107!GO:0044237;cellular metabolic process;7.58766766943318e-107!GO:0044238;primary metabolic process;1.24896095848902e-106!GO:0043170;macromolecule metabolic process;3.05724628741355e-104!GO:0030529;ribonucleoprotein complex;2.36154721285953e-95!GO:0044428;nuclear part;2.50162780289223e-86!GO:0003723;RNA binding;2.02899865388162e-84!GO:0043233;organelle lumen;4.40311968891335e-76!GO:0031974;membrane-enclosed lumen;4.40311968891335e-76!GO:0043283;biopolymer metabolic process;8.82382988887916e-71!GO:0005515;protein binding;2.3071827165795e-69!GO:0010467;gene expression;7.01662749665191e-65!GO:0005739;mitochondrion;3.69621803871577e-64!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.10274895716195e-63!GO:0005840;ribosome;2.17975816356968e-57!GO:0006396;RNA processing;5.65451102512374e-57!GO:0006412;translation;6.46318193427531e-55!GO:0016043;cellular component organization and biogenesis;5.19302910336845e-53!GO:0043234;protein complex;6.45920274806805e-53!GO:0003735;structural constituent of ribosome;2.14289080426227e-50!GO:0031981;nuclear lumen;1.01764705693543e-49!GO:0031090;organelle membrane;1.17314458592469e-49!GO:0043228;non-membrane-bound organelle;6.42600532770415e-48!GO:0043232;intracellular non-membrane-bound organelle;6.42600532770415e-48!GO:0006996;organelle organization and biogenesis;3.10259901311973e-45!GO:0019538;protein metabolic process;5.20831181763127e-45!GO:0003676;nucleic acid binding;1.01740106045097e-44!GO:0033279;ribosomal subunit;9.98698082083884e-44!GO:0016071;mRNA metabolic process;1.08871090463973e-43!GO:0044429;mitochondrial part;1.84369309635564e-43!GO:0009058;biosynthetic process;2.39446960061101e-43!GO:0031967;organelle envelope;9.03109130707508e-43!GO:0044249;cellular biosynthetic process;1.2919653598807e-42!GO:0031975;envelope;1.77045267813685e-42!GO:0009059;macromolecule biosynthetic process;1.54836470110984e-40!GO:0008380;RNA splicing;1.75341971999466e-40!GO:0044267;cellular protein metabolic process;3.84849945273406e-40!GO:0044260;cellular macromolecule metabolic process;1.07763461387766e-39!GO:0033036;macromolecule localization;6.98978148702197e-39!GO:0015031;protein transport;7.953744900826e-39!GO:0006259;DNA metabolic process;1.15667312564178e-36!GO:0006397;mRNA processing;2.03841239759053e-36!GO:0022613;ribonucleoprotein complex biogenesis and assembly;7.67379880308028e-36!GO:0046907;intracellular transport;3.28291527695955e-35!GO:0065003;macromolecular complex assembly;8.17846447729846e-35!GO:0016070;RNA metabolic process;1.43676216058499e-34!GO:0008104;protein localization;3.80541596714773e-34!GO:0045184;establishment of protein localization;1.41290548370441e-33!GO:0022607;cellular component assembly;6.38806378077344e-33!GO:0005829;cytosol;4.93653532801165e-32!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.40462389860928e-31!GO:0000166;nucleotide binding;3.08478639720224e-30!GO:0005654;nucleoplasm;3.08939289658394e-29!GO:0007049;cell cycle;3.60655923988044e-29!GO:0005681;spliceosome;7.26365516613365e-29!GO:0019866;organelle inner membrane;4.16916451153717e-28!GO:0005740;mitochondrial envelope;8.23496389889258e-28!GO:0006886;intracellular protein transport;8.25602481046777e-27!GO:0031966;mitochondrial membrane;5.97214470050066e-26!GO:0005743;mitochondrial inner membrane;2.31331994933969e-25!GO:0044445;cytosolic part;5.6254303277797e-24!GO:0051649;establishment of cellular localization;1.31742283945274e-23!GO:0006119;oxidative phosphorylation;2.14029053529237e-23!GO:0051641;cellular localization;2.50733155055494e-23!GO:0015934;large ribosomal subunit;4.09750248910852e-23!GO:0005694;chromosome;4.74603269165645e-23!GO:0044451;nucleoplasm part;7.26852385334403e-23!GO:0016462;pyrophosphatase activity;4.36341969673911e-22!GO:0005730;nucleolus;4.92644909542023e-22!GO:0016817;hydrolase activity, acting on acid anhydrides;8.43935357309921e-22!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;9.8362997452715e-22!GO:0015935;small ribosomal subunit;1.01077569000266e-21!GO:0022402;cell cycle process;1.06723500345413e-21!GO:0032553;ribonucleotide binding;1.50174593081593e-21!GO:0032555;purine ribonucleotide binding;1.50174593081593e-21!GO:0017111;nucleoside-triphosphatase activity;1.90916823996497e-21!GO:0000278;mitotic cell cycle;3.8772920706213e-21!GO:0006974;response to DNA damage stimulus;5.02573445876448e-21!GO:0012505;endomembrane system;6.94494371565947e-21!GO:0017076;purine nucleotide binding;2.46254721002197e-20!GO:0044455;mitochondrial membrane part;3.04805822820371e-20!GO:0022618;protein-RNA complex assembly;3.6293364103426e-20!GO:0044427;chromosomal part;1.03595442110261e-19!GO:0016874;ligase activity;1.63577737632526e-19!GO:0044265;cellular macromolecule catabolic process;3.60029453540536e-19!GO:0022403;cell cycle phase;4.38140629407303e-19!GO:0005524;ATP binding;4.44749731964724e-19!GO:0006512;ubiquitin cycle;8.02000374701281e-19!GO:0032559;adenyl ribonucleotide binding;1.18188916027583e-18!GO:0051276;chromosome organization and biogenesis;1.25069517602163e-18!GO:0031980;mitochondrial lumen;1.74252408903923e-18!GO:0005759;mitochondrial matrix;1.74252408903923e-18!GO:0000087;M phase of mitotic cell cycle;2.91038396305149e-18!GO:0007067;mitosis;4.35268414956018e-18!GO:0051603;proteolysis involved in cellular protein catabolic process;8.63462073851439e-18!GO:0019941;modification-dependent protein catabolic process;1.81068647024177e-17!GO:0043632;modification-dependent macromolecule catabolic process;1.81068647024177e-17!GO:0044257;cellular protein catabolic process;2.49495281958623e-17!GO:0030554;adenyl nucleotide binding;2.86645419471492e-17!GO:0006511;ubiquitin-dependent protein catabolic process;3.36877145507918e-17!GO:0048770;pigment granule;3.5888802134075e-17!GO:0042470;melanosome;3.5888802134075e-17!GO:0006281;DNA repair;5.63796433140046e-17!GO:0043285;biopolymer catabolic process;6.01794903559565e-17!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);7.81401750955805e-17!GO:0051301;cell division;8.1510341295721e-17!GO:0006457;protein folding;1.1266383470101e-16!GO:0042254;ribosome biogenesis and assembly;1.28683700104682e-16!GO:0005746;mitochondrial respiratory chain;1.72294473447697e-16!GO:0009057;macromolecule catabolic process;1.76617039200068e-16!GO:0044453;nuclear membrane part;1.91589323675509e-16!GO:0000279;M phase;2.00713429321412e-16!GO:0008135;translation factor activity, nucleic acid binding;2.62645250994024e-16!GO:0043412;biopolymer modification;2.65084343566032e-16!GO:0031965;nuclear membrane;3.38431943446678e-16!GO:0006260;DNA replication;5.32949400498127e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;7.67025648751301e-16!GO:0005761;mitochondrial ribosome;7.67025648751301e-16!GO:0000313;organellar ribosome;7.67025648751301e-16!GO:0005635;nuclear envelope;8.71964745334479e-16!GO:0050136;NADH dehydrogenase (quinone) activity;1.61908302310062e-15!GO:0003954;NADH dehydrogenase activity;1.61908302310062e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.61908302310062e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;3.8507716841013e-15!GO:0000375;RNA splicing, via transesterification reactions;3.8507716841013e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;3.8507716841013e-15!GO:0030163;protein catabolic process;4.30306320735329e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);7.50948282695908e-15!GO:0005794;Golgi apparatus;1.21667916427055e-14!GO:0005643;nuclear pore;2.74083676605044e-14!GO:0009719;response to endogenous stimulus;2.86176036941555e-14!GO:0006605;protein targeting;3.27017542737575e-14!GO:0042623;ATPase activity, coupled;3.28412363190938e-14!GO:0006325;establishment and/or maintenance of chromatin architecture;3.47162017528883e-14!GO:0016887;ATPase activity;3.73329504337053e-14!GO:0005783;endoplasmic reticulum;6.29404482059283e-14!GO:0051186;cofactor metabolic process;6.29404482059283e-14!GO:0008134;transcription factor binding;6.65762350806175e-14!GO:0006403;RNA localization;1.01000979657763e-13!GO:0006323;DNA packaging;1.22051143657867e-13!GO:0006464;protein modification process;1.23286991778636e-13!GO:0042775;organelle ATP synthesis coupled electron transport;1.35850634494395e-13!GO:0042773;ATP synthesis coupled electron transport;1.35850634494395e-13!GO:0044248;cellular catabolic process;1.9641544881036e-13!GO:0030964;NADH dehydrogenase complex (quinone);2.51479614315175e-13!GO:0045271;respiratory chain complex I;2.51479614315175e-13!GO:0005747;mitochondrial respiratory chain complex I;2.51479614315175e-13!GO:0050657;nucleic acid transport;2.78838022236955e-13!GO:0051236;establishment of RNA localization;2.78838022236955e-13!GO:0050658;RNA transport;2.78838022236955e-13!GO:0004386;helicase activity;4.13927661417323e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;7.8750507443198e-13!GO:0050794;regulation of cellular process;8.25253045966869e-13!GO:0051082;unfolded protein binding;1.22406915794639e-12!GO:0006413;translational initiation;1.42595266240803e-12!GO:0000502;proteasome complex (sensu Eukaryota);1.42688324520031e-12!GO:0006399;tRNA metabolic process;1.42688324520031e-12!GO:0006732;coenzyme metabolic process;1.52508863452298e-12!GO:0065002;intracellular protein transport across a membrane;2.39307844368091e-12!GO:0006446;regulation of translational initiation;2.69389516099545e-12!GO:0043687;post-translational protein modification;2.887360235907e-12!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;3.39310599475112e-12!GO:0006913;nucleocytoplasmic transport;3.45726603632655e-12!GO:0003743;translation initiation factor activity;4.59212768686358e-12!GO:0016604;nuclear body;4.76423948812491e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;7.75995886771956e-12!GO:0019222;regulation of metabolic process;9.44782516046219e-12!GO:0044432;endoplasmic reticulum part;1.22650635322723e-11!GO:0051028;mRNA transport;1.28825723171095e-11!GO:0051169;nuclear transport;1.40931514134875e-11!GO:0008026;ATP-dependent helicase activity;1.46718116768189e-11!GO:0048193;Golgi vesicle transport;3.00441191040069e-11!GO:0006364;rRNA processing;4.46115150253245e-11!GO:0046930;pore complex;5.00248976481749e-11!GO:0000785;chromatin;8.14714870927065e-11!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.34109346646256e-10!GO:0015630;microtubule cytoskeleton;1.71699882602305e-10!GO:0016072;rRNA metabolic process;1.83244103851404e-10!GO:0016607;nuclear speck;2.90008886654004e-10!GO:0006461;protein complex assembly;3.2933567021827e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;3.79852381710666e-10!GO:0008565;protein transporter activity;5.08349793716132e-10!GO:0008639;small protein conjugating enzyme activity;6.14199538968796e-10!GO:0030532;small nuclear ribonucleoprotein complex;6.638131504167e-10!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.3045394606814e-09!GO:0004842;ubiquitin-protein ligase activity;1.35834311455125e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.74178180463609e-09!GO:0004812;aminoacyl-tRNA ligase activity;1.74178180463609e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.74178180463609e-09!GO:0019787;small conjugating protein ligase activity;2.14037061462231e-09!GO:0016192;vesicle-mediated transport;2.72178023390371e-09!GO:0015986;ATP synthesis coupled proton transport;3.19769512963379e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;3.19769512963379e-09!GO:0065004;protein-DNA complex assembly;3.29895564208571e-09!GO:0009259;ribonucleotide metabolic process;4.8384882938545e-09!GO:0000074;regulation of progression through cell cycle;4.93296222298602e-09!GO:0005793;ER-Golgi intermediate compartment;4.95333849229943e-09!GO:0050789;regulation of biological process;5.57507214038963e-09!GO:0043038;amino acid activation;5.67886729007958e-09!GO:0006418;tRNA aminoacylation for protein translation;5.67886729007958e-09!GO:0043039;tRNA aminoacylation;5.67886729007958e-09!GO:0016740;transferase activity;5.74488714462701e-09!GO:0031323;regulation of cellular metabolic process;5.95720240703172e-09!GO:0006366;transcription from RNA polymerase II promoter;5.98595052006548e-09!GO:0009055;electron carrier activity;6.05750902825088e-09!GO:0051726;regulation of cell cycle;6.24761224750508e-09!GO:0051188;cofactor biosynthetic process;7.69306549604284e-09!GO:0006163;purine nucleotide metabolic process;8.5749841933319e-09!GO:0017038;protein import;1.2260571421064e-08!GO:0006261;DNA-dependent DNA replication;1.24827071597696e-08!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.49550484052839e-08!GO:0016568;chromatin modification;1.54572850142783e-08!GO:0019829;cation-transporting ATPase activity;1.56837141457521e-08!GO:0006164;purine nucleotide biosynthetic process;2.09822768421911e-08!GO:0005789;endoplasmic reticulum membrane;2.9287972331651e-08!GO:0012501;programmed cell death;2.96504080754109e-08!GO:0016469;proton-transporting two-sector ATPase complex;2.99590734226018e-08!GO:0007010;cytoskeleton organization and biogenesis;3.14895609199379e-08!GO:0006350;transcription;3.30498635476385e-08!GO:0006915;apoptosis;3.34676238034405e-08!GO:0006333;chromatin assembly or disassembly;3.37466713499074e-08!GO:0009260;ribonucleotide biosynthetic process;3.41323968270259e-08!GO:0009150;purine ribonucleotide metabolic process;3.45649323780533e-08!GO:0009108;coenzyme biosynthetic process;3.60287186415088e-08!GO:0015078;hydrogen ion transmembrane transporter activity;4.17656647737296e-08!GO:0003712;transcription cofactor activity;5.03275305069613e-08!GO:0016881;acid-amino acid ligase activity;5.55258956253413e-08!GO:0003697;single-stranded DNA binding;7.10305497881068e-08!GO:0044431;Golgi apparatus part;7.68487688105318e-08!GO:0009152;purine ribonucleotide biosynthetic process;8.40815584188989e-08!GO:0009060;aerobic respiration;8.93327397165027e-08!GO:0009142;nucleoside triphosphate biosynthetic process;1.18058730741799e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.18058730741799e-07!GO:0006754;ATP biosynthetic process;1.2561104447978e-07!GO:0006753;nucleoside phosphate metabolic process;1.2561104447978e-07!GO:0009199;ribonucleoside triphosphate metabolic process;1.39920595333803e-07!GO:0010468;regulation of gene expression;1.53694600716184e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.58924576517435e-07!GO:0032446;protein modification by small protein conjugation;1.64006075616162e-07!GO:0006752;group transfer coenzyme metabolic process;1.83133389549634e-07!GO:0009141;nucleoside triphosphate metabolic process;1.87258442160673e-07!GO:0051246;regulation of protein metabolic process;1.91342577633767e-07!GO:0000245;spliceosome assembly;2.16613361746126e-07!GO:0043566;structure-specific DNA binding;2.23802632686708e-07!GO:0007005;mitochondrion organization and biogenesis;2.27647706999074e-07!GO:0016779;nucleotidyltransferase activity;2.33900358890071e-07!GO:0046034;ATP metabolic process;2.42221616764835e-07!GO:0006793;phosphorus metabolic process;2.8378988734549e-07!GO:0006796;phosphate metabolic process;2.8378988734549e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.91904305795115e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.91904305795115e-07!GO:0031988;membrane-bound vesicle;2.99301686260566e-07!GO:0000775;chromosome, pericentric region;3.14405939866474e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.28417901716609e-07!GO:0009144;purine nucleoside triphosphate metabolic process;3.28417901716609e-07!GO:0016023;cytoplasmic membrane-bound vesicle;3.47938214936391e-07!GO:0016567;protein ubiquitination;3.72976035458706e-07!GO:0005768;endosome;4.46847063032816e-07!GO:0005819;spindle;4.59411566100998e-07!GO:0045333;cellular respiration;4.8534474873079e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;4.9687926282827e-07!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;6.03242197245752e-07!GO:0009056;catabolic process;7.67368461901241e-07!GO:0003724;RNA helicase activity;7.8627247606755e-07!GO:0008219;cell death;1.00467989330478e-06!GO:0016265;death;1.00467989330478e-06!GO:0045259;proton-transporting ATP synthase complex;1.02369896672194e-06!GO:0043623;cellular protein complex assembly;1.06285947757512e-06!GO:0032774;RNA biosynthetic process;1.51827755197274e-06!GO:0000139;Golgi membrane;1.53846516402948e-06!GO:0008094;DNA-dependent ATPase activity;1.74113704196602e-06!GO:0006888;ER to Golgi vesicle-mediated transport;1.77906429504755e-06!GO:0007051;spindle organization and biogenesis;1.82358454573924e-06!GO:0006099;tricarboxylic acid cycle;1.83997297999384e-06!GO:0046356;acetyl-CoA catabolic process;1.83997297999384e-06!GO:0031982;vesicle;1.87967969947709e-06!GO:0006351;transcription, DNA-dependent;1.91620093124537e-06!GO:0005667;transcription factor complex;1.97092352906985e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;2.32408656531163e-06!GO:0003899;DNA-directed RNA polymerase activity;2.32408656531163e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;2.45536461120321e-06!GO:0031410;cytoplasmic vesicle;2.45536461120321e-06!GO:0031497;chromatin assembly;2.51482938373896e-06!GO:0048475;coated membrane;2.55272000456058e-06!GO:0030117;membrane coat;2.55272000456058e-06!GO:0006084;acetyl-CoA metabolic process;3.05770082582888e-06!GO:0051170;nuclear import;3.17002481210363e-06!GO:0009117;nucleotide metabolic process;3.3198307779034e-06!GO:0006334;nucleosome assembly;3.33810324208451e-06!GO:0016310;phosphorylation;3.64093490394055e-06!GO:0000151;ubiquitin ligase complex;5.39384550022471e-06!GO:0005874;microtubule;5.777448642738e-06!GO:0051168;nuclear export;6.04306250859399e-06!GO:0005762;mitochondrial large ribosomal subunit;6.12186632733034e-06!GO:0000315;organellar large ribosomal subunit;6.12186632733034e-06!GO:0051325;interphase;6.93794581925458e-06!GO:0005657;replication fork;7.58329340785057e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;8.98296480997594e-06!GO:0006606;protein import into nucleus;9.02276569872745e-06!GO:0000314;organellar small ribosomal subunit;9.43739022420496e-06!GO:0005763;mitochondrial small ribosomal subunit;9.43739022420496e-06!GO:0009109;coenzyme catabolic process;1.06894440496631e-05!GO:0051329;interphase of mitotic cell cycle;1.09306089888462e-05!GO:0005813;centrosome;1.09306089888462e-05!GO:0031252;leading edge;1.13601984681574e-05!GO:0030120;vesicle coat;1.26962437312963e-05!GO:0030662;coated vesicle membrane;1.26962437312963e-05!GO:0007017;microtubule-based process;1.28264060557089e-05!GO:0007059;chromosome segregation;1.31397935286081e-05!GO:0051187;cofactor catabolic process;1.5650710751073e-05!GO:0003924;GTPase activity;1.82728890322693e-05!GO:0008186;RNA-dependent ATPase activity;2.08210037274313e-05!GO:0045449;regulation of transcription;2.21382952076148e-05!GO:0005815;microtubule organizing center;3.51065372975115e-05!GO:0005525;GTP binding;3.51065372975115e-05!GO:0043069;negative regulation of programmed cell death;3.56779846904767e-05!GO:0003729;mRNA binding;3.71914051798603e-05!GO:0045454;cell redox homeostasis;3.87021045587039e-05!GO:0043066;negative regulation of apoptosis;4.14370642766615e-05!GO:0006613;cotranslational protein targeting to membrane;4.18681693082079e-05!GO:0000075;cell cycle checkpoint;4.44601436777562e-05!GO:0008654;phospholipid biosynthetic process;4.50159018628029e-05!GO:0000226;microtubule cytoskeleton organization and biogenesis;5.32925038278799e-05!GO:0005770;late endosome;6.61211968149746e-05!GO:0003678;DNA helicase activity;6.81487756813686e-05!GO:0008033;tRNA processing;6.90762545705258e-05!GO:0004004;ATP-dependent RNA helicase activity;6.96559653073461e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;7.00061156014208e-05!GO:0016363;nuclear matrix;7.60417200410823e-05!GO:0016564;transcription repressor activity;7.61572718078485e-05!GO:0003690;double-stranded DNA binding;7.86623295891089e-05!GO:0005788;endoplasmic reticulum lumen;8.5089581225069e-05!GO:0003677;DNA binding;8.59519298267351e-05!GO:0006302;double-strand break repair;8.77006654436591e-05!GO:0005769;early endosome;9.4921324332547e-05!GO:0051052;regulation of DNA metabolic process;0.000100459358865092!GO:0048471;perinuclear region of cytoplasm;0.000100459358865092!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000103613760912361!GO:0042802;identical protein binding;0.000109490366490565!GO:0016853;isomerase activity;0.000123197535991194!GO:0006355;regulation of transcription, DNA-dependent;0.000132797497669094!GO:0042981;regulation of apoptosis;0.000134646129432155!GO:0000776;kinetochore;0.000134646129432155!GO:0008092;cytoskeletal protein binding;0.000134936237540438!GO:0032508;DNA duplex unwinding;0.00014511356922257!GO:0032392;DNA geometric change;0.00014511356922257!GO:0044452;nucleolar part;0.000147306951899696!GO:0043681;protein import into mitochondrion;0.000155805245756685!GO:0065007;biological regulation;0.000165458493896111!GO:0043067;regulation of programmed cell death;0.000170040440052538!GO:0019899;enzyme binding;0.000184755514960191!GO:0007006;mitochondrial membrane organization and biogenesis;0.00019528602712774!GO:0006916;anti-apoptosis;0.000208087673698246!GO:0006402;mRNA catabolic process;0.000221449877279733!GO:0043021;ribonucleoprotein binding;0.000221667565600871!GO:0051427;hormone receptor binding;0.000234049283410737!GO:0048523;negative regulation of cellular process;0.00023484683865413!GO:0000059;protein import into nucleus, docking;0.000254877749705946!GO:0032561;guanyl ribonucleotide binding;0.00025850158131735!GO:0019001;guanyl nucleotide binding;0.00025850158131735!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000275806665107109!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000275930890973271!GO:0030880;RNA polymerase complex;0.000278835624090734!GO:0031324;negative regulation of cellular metabolic process;0.000293902935496892!GO:0030036;actin cytoskeleton organization and biogenesis;0.000295647699183664!GO:0003714;transcription corepressor activity;0.000306915512374838!GO:0044440;endosomal part;0.000313123470519177!GO:0010008;endosome membrane;0.000313123470519177!GO:0006612;protein targeting to membrane;0.00036431196121784!GO:0006818;hydrogen transport;0.000368642203833778!GO:0016787;hydrolase activity;0.000372214696351235!GO:0006268;DNA unwinding during replication;0.000374254000558126!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000379801824405906!GO:0005798;Golgi-associated vesicle;0.000393393511364578!GO:0006401;RNA catabolic process;0.000424016051199363!GO:0003682;chromatin binding;0.000441295225008309!GO:0035257;nuclear hormone receptor binding;0.00045010983873478!GO:0007088;regulation of mitosis;0.000450828794161962!GO:0000228;nuclear chromosome;0.00046616563612949!GO:0006520;amino acid metabolic process;0.000469831418845926!GO:0005839;proteasome core complex (sensu Eukaryota);0.000500671264717702!GO:0007264;small GTPase mediated signal transduction;0.000519605228305546!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000521730864768349!GO:0005684;U2-dependent spliceosome;0.000536067063535516!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000538028673382293!GO:0005637;nuclear inner membrane;0.000546116453802812!GO:0009165;nucleotide biosynthetic process;0.000547993046749474!GO:0015992;proton transport;0.000547993046749474!GO:0051087;chaperone binding;0.000588122040720886!GO:0006383;transcription from RNA polymerase III promoter;0.000638817543338865!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000643936715662536!GO:0000428;DNA-directed RNA polymerase complex;0.000643936715662536!GO:0008250;oligosaccharyl transferase complex;0.000647515136942905!GO:0006414;translational elongation;0.000650368772628487!GO:0030029;actin filament-based process;0.000652363888425375!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000683299914774032!GO:0004298;threonine endopeptidase activity;0.000683299914774032!GO:0006839;mitochondrial transport;0.000724360864768467!GO:0004576;oligosaccharyl transferase activity;0.00073187948396184!GO:0009892;negative regulation of metabolic process;0.000731923724791595!GO:0051920;peroxiredoxin activity;0.000754494426833764!GO:0033116;ER-Golgi intermediate compartment membrane;0.000778273969562575!GO:0001726;ruffle;0.000829405496704981!GO:0005885;Arp2/3 protein complex;0.000846291897806625!GO:0046474;glycerophospholipid biosynthetic process;0.000897809014831026!GO:0007052;mitotic spindle organization and biogenesis;0.000904225063900385!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000912431170000236!GO:0016741;transferase activity, transferring one-carbon groups;0.000934474455343154!GO:0015631;tubulin binding;0.000946184345587867!GO:0031072;heat shock protein binding;0.000990746453821941!GO:0008168;methyltransferase activity;0.00103712503376784!GO:0006626;protein targeting to mitochondrion;0.00111677405896113!GO:0004674;protein serine/threonine kinase activity;0.00112846937476976!GO:0015980;energy derivation by oxidation of organic compounds;0.00116792811747736!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00118361842511648!GO:0000049;tRNA binding;0.00118361842511648!GO:0022890;inorganic cation transmembrane transporter activity;0.00118723456179613!GO:0030867;rough endoplasmic reticulum membrane;0.00122288618619069!GO:0016251;general RNA polymerase II transcription factor activity;0.00128984186929679!GO:0007093;mitotic cell cycle checkpoint;0.00134303320302902!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00136651876690103!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00136651876690103!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00136651876690103!GO:0005669;transcription factor TFIID complex;0.00138447859138851!GO:0005773;vacuole;0.00139744451915316!GO:0048519;negative regulation of biological process;0.0014110537696743!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00143964480728557!GO:0048487;beta-tubulin binding;0.00150497036988323!GO:0006611;protein export from nucleus;0.00150779301830218!GO:0006275;regulation of DNA replication;0.00162003626353132!GO:0003713;transcription coactivator activity;0.0017231064773672!GO:0051789;response to protein stimulus;0.00179864197029091!GO:0006986;response to unfolded protein;0.00179864197029091!GO:0006338;chromatin remodeling;0.00188023937138051!GO:0000725;recombinational repair;0.00188959920267849!GO:0000724;double-strand break repair via homologous recombination;0.00188959920267849!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00195430982766582!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00195430982766582!GO:0005048;signal sequence binding;0.00197130205719898!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00198493563727664!GO:0016563;transcription activator activity;0.00199053332194263!GO:0016126;sterol biosynthetic process;0.00207009046949009!GO:0006405;RNA export from nucleus;0.00212629963818982!GO:0003684;damaged DNA binding;0.00225312906630284!GO:0040029;regulation of gene expression, epigenetic;0.00226496784522042!GO:0004527;exonuclease activity;0.00232766212160058!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0023888381804151!GO:0044262;cellular carbohydrate metabolic process;0.00257678373642739!GO:0044454;nuclear chromosome part;0.00260122489589922!GO:0006310;DNA recombination;0.00262178289508667!GO:0006541;glutamine metabolic process;0.00272137209793279!GO:0043414;biopolymer methylation;0.00272506656808318!GO:0005905;coated pit;0.00276439830537359!GO:0000792;heterochromatin;0.0027829547263273!GO:0006352;transcription initiation;0.00279049588776628!GO:0046467;membrane lipid biosynthetic process;0.00285336555843218!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.00292553695583743!GO:0006284;base-excision repair;0.00296164649090223!GO:0005791;rough endoplasmic reticulum;0.00306537898346849!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00319134287297487!GO:0045786;negative regulation of progression through cell cycle;0.00355307624217716!GO:0006144;purine base metabolic process;0.00360419327569698!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.00362773058889804!GO:0015399;primary active transmembrane transporter activity;0.00362773058889804!GO:0008652;amino acid biosynthetic process;0.00367165984017433!GO:0031968;organelle outer membrane;0.00368054518299956!GO:0030118;clathrin coat;0.00374892498116974!GO:0009112;nucleobase metabolic process;0.00376500995653598!GO:0019867;outer membrane;0.00380713264755352!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00385979178760057!GO:0008270;zinc ion binding;0.00390732451470172!GO:0018196;peptidyl-asparagine modification;0.0043083890698221!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0043083890698221!GO:0031124;mRNA 3'-end processing;0.00444685096381595!GO:0000786;nucleosome;0.0044886780025304!GO:0008139;nuclear localization sequence binding;0.0045029644633409!GO:0016859;cis-trans isomerase activity;0.00458270466370448!GO:0032259;methylation;0.00460652285840447!GO:0004003;ATP-dependent DNA helicase activity;0.00471111969973829!GO:0000096;sulfur amino acid metabolic process;0.00483084798601963!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00493374967255957!GO:0051252;regulation of RNA metabolic process;0.00493374967255957!GO:0030134;ER to Golgi transport vesicle;0.0049400393370149!GO:0005741;mitochondrial outer membrane;0.00503651389370544!GO:0003746;translation elongation factor activity;0.00518912710997142!GO:0030433;ER-associated protein catabolic process;0.00564438542228744!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.00564438542228744!GO:0000793;condensed chromosome;0.00565376623966904!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.0058375033254849!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00588255692748125!GO:0030027;lamellipodium;0.00590957595644819!GO:0051053;negative regulation of DNA metabolic process;0.00609993543817534!GO:0006730;one-carbon compound metabolic process;0.0063926425419768!GO:0016272;prefoldin complex;0.00646352970926191!GO:0043022;ribosome binding;0.00655312193670587!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0069326210361932!GO:0015002;heme-copper terminal oxidase activity;0.0069326210361932!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0069326210361932!GO:0004129;cytochrome-c oxidase activity;0.0069326210361932!GO:0030658;transport vesicle membrane;0.00705357838229477!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.00705357838229477!GO:0043596;nuclear replication fork;0.00741740113287664!GO:0000339;RNA cap binding;0.00744809755110823!GO:0030119;AP-type membrane coat adaptor complex;0.00779187449139731!GO:0016481;negative regulation of transcription;0.00779187449139731!GO:0048500;signal recognition particle;0.00791393444947245!GO:0007021;tubulin folding;0.00806625601631788!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00807793824363633!GO:0005876;spindle microtubule;0.00826738163481762!GO:0030133;transport vesicle;0.00838287870784747!GO:0006270;DNA replication initiation;0.00858122141351301!GO:0006650;glycerophospholipid metabolic process;0.00873561724148698!GO:0030127;COPII vesicle coat;0.00882081971717286!GO:0012507;ER to Golgi transport vesicle membrane;0.00882081971717286!GO:0006695;cholesterol biosynthetic process;0.00909067110403307!GO:0030176;integral to endoplasmic reticulum membrane;0.00918722306415308!GO:0051656;establishment of organelle localization;0.00919311791965432!GO:0006376;mRNA splice site selection;0.00936025876310722!GO:0000389;nuclear mRNA 3'-splice site recognition;0.00936025876310722!GO:0006007;glucose catabolic process;0.00937192080460006!GO:0016044;membrane organization and biogenesis;0.00942610256100237!GO:0006595;polyamine metabolic process;0.00953556604441794!GO:0000178;exosome (RNase complex);0.0100096512558686!GO:0019843;rRNA binding;0.0101548143056569!GO:0005832;chaperonin-containing T-complex;0.0102056471361325!GO:0000922;spindle pole;0.0102056471361325!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0103027680431614!GO:0019783;small conjugating protein-specific protease activity;0.0105754368298113!GO:0030131;clathrin adaptor complex;0.0111114065461189!GO:0035258;steroid hormone receptor binding;0.01133910559129!GO:0008610;lipid biosynthetic process;0.0114720531640954!GO:0003756;protein disulfide isomerase activity;0.0116556813980905!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0116556813980905!GO:0003711;transcription elongation regulator activity;0.0118175165805084!GO:0016791;phosphoric monoester hydrolase activity;0.0119835231333077!GO:0045947;negative regulation of translational initiation;0.0120708716049528!GO:0000323;lytic vacuole;0.0124634777798784!GO:0005764;lysosome;0.0124634777798784!GO:0030132;clathrin coat of coated pit;0.0124674105654632!GO:0009116;nucleoside metabolic process;0.0125385474162537!GO:0032200;telomere organization and biogenesis;0.0127721736571994!GO:0000723;telomere maintenance;0.0127721736571994!GO:0016584;nucleosome positioning;0.0129282223685566!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0131604263806184!GO:0006519;amino acid and derivative metabolic process;0.013295775665061!GO:0005758;mitochondrial intermembrane space;0.0135679757773065!GO:0004532;exoribonuclease activity;0.0135679757773065!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0135679757773065!GO:0045045;secretory pathway;0.0136286203533889!GO:0006417;regulation of translation;0.0139980141958043!GO:0000082;G1/S transition of mitotic cell cycle;0.0140631737996722!GO:0030660;Golgi-associated vesicle membrane;0.0140683355503199!GO:0008312;7S RNA binding;0.0145170378312412!GO:0050178;phenylpyruvate tautomerase activity;0.0145535249661409!GO:0006984;ER-nuclear signaling pathway;0.0149197425737835!GO:0000097;sulfur amino acid biosynthetic process;0.015057269977733!GO:0031123;RNA 3'-end processing;0.0153505240861862!GO:0051287;NAD binding;0.01567664780726!GO:0019318;hexose metabolic process;0.0158250436712893!GO:0046483;heterocycle metabolic process;0.0162923502892326!GO:0004843;ubiquitin-specific protease activity;0.0167240874152275!GO:0009451;RNA modification;0.0167350405496106!GO:0008180;signalosome;0.0167368700707049!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0168791900452259!GO:0008156;negative regulation of DNA replication;0.0169742023580153!GO:0030031;cell projection biogenesis;0.0170109798008189!GO:0042393;histone binding;0.0171415524601383!GO:0046489;phosphoinositide biosynthetic process;0.017589253460117!GO:0006733;oxidoreduction coenzyme metabolic process;0.0176722000785603!GO:0016301;kinase activity;0.017773087425189!GO:0008629;induction of apoptosis by intracellular signals;0.0180752939647521!GO:0031901;early endosome membrane;0.0181945843281224!GO:0030663;COPI coated vesicle membrane;0.0181945843281224!GO:0030126;COPI vesicle coat;0.0181945843281224!GO:0016197;endosome transport;0.0181982522631332!GO:0005996;monosaccharide metabolic process;0.0182590849917458!GO:0043488;regulation of mRNA stability;0.0186180576144822!GO:0043487;regulation of RNA stability;0.0186180576144822!GO:0001725;stress fiber;0.0186809028674914!GO:0032432;actin filament bundle;0.0186809028674914!GO:0005774;vacuolar membrane;0.0188265389926538!GO:0008632;apoptotic program;0.0189000763617744!GO:0042770;DNA damage response, signal transduction;0.0190705244774383!GO:0000790;nuclear chromatin;0.0192224025786938!GO:0030659;cytoplasmic vesicle membrane;0.019234575215858!GO:0006378;mRNA polyadenylation;0.0193885398604363!GO:0065009;regulation of a molecular function;0.0196522991670705!GO:0044433;cytoplasmic vesicle part;0.0199622644561619!GO:0006607;NLS-bearing substrate import into nucleus;0.0203959124802081!GO:0006306;DNA methylation;0.0205939315727346!GO:0006305;DNA alkylation;0.0205939315727346!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0205970005476852!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0208488338943046!GO:0045047;protein targeting to ER;0.0208488338943046!GO:0000209;protein polyubiquitination;0.0209952635771859!GO:0045892;negative regulation of transcription, DNA-dependent;0.0210942022390665!GO:0043492;ATPase activity, coupled to movement of substances;0.0211006292353336!GO:0012506;vesicle membrane;0.021761233958427!GO:0030521;androgen receptor signaling pathway;0.0222630554120569!GO:0019752;carboxylic acid metabolic process;0.0223798814325863!GO:0001701;in utero embryonic development;0.0225667771088744!GO:0006790;sulfur metabolic process;0.0226924501479896!GO:0005862;muscle thin filament tropomyosin;0.0229992787808797!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0233349104178662!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0243235663549077!GO:0051128;regulation of cellular component organization and biogenesis;0.0248159149084171!GO:0008287;protein serine/threonine phosphatase complex;0.0248776383977954!GO:0016311;dephosphorylation;0.0248776383977954!GO:0046983;protein dimerization activity;0.0248776383977954!GO:0004518;nuclease activity;0.0250196149361908!GO:0005652;nuclear lamina;0.0251017843085164!GO:0000152;nuclear ubiquitin ligase complex;0.0252564527297885!GO:0006082;organic acid metabolic process;0.0252751992793747!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.025452285114593!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0257308924460473!GO:0045039;protein import into mitochondrial inner membrane;0.0257308924460473!GO:0046426;negative regulation of JAK-STAT cascade;0.0264869732044746!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.026556554517304!GO:0000819;sister chromatid segregation;0.0272325777302166!GO:0031570;DNA integrity checkpoint;0.0272893901206122!GO:0031577;spindle checkpoint;0.0274322773656027!GO:0031970;organelle envelope lumen;0.0276324207236123!GO:0007040;lysosome organization and biogenesis;0.0278962104452825!GO:0006643;membrane lipid metabolic process;0.0279747894479185!GO:0030496;midbody;0.0281865511238608!GO:0008536;Ran GTPase binding;0.0282746006263605!GO:0008017;microtubule binding;0.0286999651426311!GO:0005784;translocon complex;0.0298485508394797!GO:0006767;water-soluble vitamin metabolic process;0.0303566076432538!GO:0006891;intra-Golgi vesicle-mediated transport;0.0303594584413978!GO:0005663;DNA replication factor C complex;0.0308318900550399!GO:0051101;regulation of DNA binding;0.0322722912385966!GO:0050811;GABA receptor binding;0.0322722912385966!GO:0004221;ubiquitin thiolesterase activity;0.0324982170345942!GO:0043601;nuclear replisome;0.0327448741739316!GO:0030894;replisome;0.0327448741739316!GO:0006304;DNA modification;0.0331475493131714!GO:0008408;3'-5' exonuclease activity;0.033666025900113!GO:0000070;mitotic sister chromatid segregation;0.0346023175667033!GO:0000910;cytokinesis;0.0353602819117284!GO:0051539;4 iron, 4 sulfur cluster binding;0.03561571061436!GO:0019904;protein domain specific binding;0.0360342812284975!GO:0006301;postreplication repair;0.0363042576245144!GO:0046870;cadmium ion binding;0.0365704097952782!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0368095112028366!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0368095112028366!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0369156183870626!GO:0050662;coenzyme binding;0.0370876203931092!GO:0031529;ruffle organization and biogenesis;0.0371630213742509!GO:0006096;glycolysis;0.0374308913478705!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0374308913478705!GO:0010257;NADH dehydrogenase complex assembly;0.0374308913478705!GO:0033108;mitochondrial respiratory chain complex assembly;0.0374308913478705!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0378118082283085!GO:0030032;lamellipodium biogenesis;0.0383828514747007!GO:0017166;vinculin binding;0.0385594123403074!GO:0031625;ubiquitin protein ligase binding;0.039343991799524!GO:0005856;cytoskeleton;0.039343991799524!GO:0008361;regulation of cell size;0.0394853564372481!GO:0004448;isocitrate dehydrogenase activity;0.0395405487564318!GO:0008022;protein C-terminus binding;0.0396022455640303!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.040951525676306!GO:0006091;generation of precursor metabolites and energy;0.0413935606427667!GO:0046365;monosaccharide catabolic process;0.0413935606427667!GO:0006740;NADPH regeneration;0.0416424532171103!GO:0006098;pentose-phosphate shunt;0.0416424532171103!GO:0043624;cellular protein complex disassembly;0.0420554354522416!GO:0035267;NuA4 histone acetyltransferase complex;0.0420554354522416!GO:0030384;phosphoinositide metabolic process;0.0422737343082418!GO:0006400;tRNA modification;0.0426554536792881!GO:0000086;G2/M transition of mitotic cell cycle;0.0428495369279352!GO:0016884;carbon-nitrogen ligase activity, with glutamine as amido-N-donor;0.042928421114244!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0429752721855371!GO:0019362;pyridine nucleotide metabolic process;0.0429816548774107!GO:0006509;membrane protein ectodomain proteolysis;0.0429879481882387!GO:0033619;membrane protein proteolysis;0.0429879481882387!GO:0051348;negative regulation of transferase activity;0.0434810205922108!GO:0000123;histone acetyltransferase complex;0.0442743725210292!GO:0008097;5S rRNA binding;0.0443455155343995!GO:0030137;COPI-coated vesicle;0.045091526524006!GO:0008637;apoptotic mitochondrial changes;0.045091526524006!GO:0009308;amine metabolic process;0.0455694906791526!GO:0031371;ubiquitin conjugating enzyme complex;0.045625458241037!GO:0009113;purine base biosynthetic process;0.0458432817722435!GO:0016417;S-acyltransferase activity;0.0458432817722435!GO:0016790;thiolester hydrolase activity;0.0460489200699217!GO:0008143;poly(A) binding;0.0470156419666196!GO:0006516;glycoprotein catabolic process;0.0474200041976455!GO:0030911;TPR domain binding;0.0475712508079026!GO:0006289;nucleotide-excision repair;0.0475787042129552!GO:0005938;cell cortex;0.047893745192659!GO:0044437;vacuolar part;0.0482985479572617!GO:0008276;protein methyltransferase activity;0.0482985479572617!GO:0006672;ceramide metabolic process;0.0483293821924112!GO:0006644;phospholipid metabolic process;0.0483779153995992!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0485177120533827!GO:0007033;vacuole organization and biogenesis;0.0485655086260162!GO:0003702;RNA polymerase II transcription factor activity;0.0486228935209058!GO:0043126;regulation of 1-phosphatidylinositol 4-kinase activity;0.0486228935209058!GO:0046813;virion attachment, binding of host cell surface receptor;0.0486228935209058!GO:0043128;positive regulation of 1-phosphatidylinositol 4-kinase activity;0.0486228935209058!GO:0006563;L-serine metabolic process;0.0488794666579856!GO:0033559;unsaturated fatty acid metabolic process;0.0491749802599822!GO:0006636;unsaturated fatty acid biosynthetic process;0.0491749802599822!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0493050434516549!GO:0030518;steroid hormone receptor signaling pathway;0.0493666713282471!GO:0009303;rRNA transcription;0.0494706047070918 | |||
|sample_id=10786 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=testis | |||
|top_motifs=OCT4_SOX2{dimer}:4.08901325988;TOPORS:2.74673017497;PITX1..3:2.46991706517;XCPE1{core}:1.6318108417;SNAI1..3:1.47812428263;SP1:1.33275462895;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.32195963567;NFY{A,B,C}:1.24202989944;ZEB1:1.15767912786;E2F1..5:1.14513840929;MTF1:1.09591821802;NKX2-3_NKX2-5:1.05377550659;CUX2:1.03553129018;SOX{8,9,10}:1.01985931506;VSX1,2:0.994657678989;TFDP1:0.957494910543;CRX:0.928400451217;SOX2:0.913074821485;RORA:0.902638655452;ONECUT1,2:0.845151028665;HIF1A:0.842315049308;AIRE:0.838879897177;MYOD1:0.79736904463;STAT1,3:0.771259941632;ATF4:0.751878712566;STAT5{A,B}:0.747846234965;ZNF143:0.725412776606;ELK1,4_GABP{A,B1}:0.688246015062;bHLH_family:0.669039493457;FOXP1:0.666944178646;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.653725114391;LEF1_TCF7_TCF7L1,2:0.653537781658;EBF1:0.641424347647;MAZ:0.626398008127;POU2F1..3:0.579211487673;POU5F1:0.566922732869;TFAP2B:0.54411499424;IKZF2:0.511280953256;LMO2:0.495943267835;GFI1:0.48221077496;SOX17:0.474356559652;PBX1:0.46045479573;TEAD1:0.443685573612;ALX1:0.442604213689;PATZ1:0.442566886894;ZNF384:0.441061589097;EVI1:0.433013631779;HOX{A5,B5}:0.429439391201;FOXQ1:0.425970052973;CDC5L:0.410911275695;NRF1:0.39733424794;SREBF1,2:0.3569905769;ESRRA:0.347867552714;NR5A1,2:0.335321133681;CDX1,2,4:0.334450871119;LHX3,4:0.279829119046;MYB:0.268832477795;NANOG:0.26510094533;ZIC1..3:0.261801217129;RBPJ:0.169063275093;GZF1:0.160109934027;TBX4,5:0.151054141344;CREB1:0.140698508786;PAX2:0.132467596548;FOXD3:0.131043699488;BREu{core}:0.115547451134;KLF4:0.113453282035;TBP:0.111638067236;TFAP2{A,C}:0.110776670746;TP53:0.107073593654;HNF4A_NR2F1,2:0.0964173395784;ZBTB16:0.0906797818058;PAX1,9:0.0659924136807;YY1:0.051211134208;TEF:0.02424256703;GATA4:0.0063719256066;IKZF1:-0.00611771466339;T:-0.0295406643001;GATA6:-0.0376542552952;ZFP161:-0.0620527518001;ZBTB6:-0.0825768839497;FOXM1:-0.0904766104449;NFE2L2:-0.0993294699199;FOXN1:-0.122579848564;ADNP_IRX_SIX_ZHX:-0.154819719374;FOX{F1,F2,J1}:-0.172413124724;MZF1:-0.173824927734;POU1F1:-0.177714067732;PPARG:-0.177874901597;FOXO1,3,4:-0.178005247314;ATF2:-0.178124742229;MYBL2:-0.189162809251;HNF1A:-0.190199159867;ATF5_CREB3:-0.190714085535;FOXA2:-0.211291807367;GTF2I:-0.221050995825;REST:-0.230929673629;UFEwm:-0.235555119789;NR6A1:-0.241627881549;SRF:-0.242301446978;EN1,2:-0.258158989699;HOX{A4,D4}:-0.27237860943;PRRX1,2:-0.276099212446;TFAP4:-0.285230038208;PAX8:-0.299344752577;FOS_FOS{B,L1}_JUN{B,D}:-0.302282351791;ZNF148:-0.308020144724;HAND1,2:-0.321329737922;BACH2:-0.332494245273;FOXL1:-0.334055267071;GCM1,2:-0.34257696577;GFI1B:-0.349239425699;EGR1..3:-0.366806036611;NFE2:-0.377390440705;FOX{I1,J2}:-0.382573072046;RREB1:-0.383323915952;ZNF423:-0.388239756559;SPZ1:-0.389156621568;POU3F1..4:-0.390874404266;HIC1:-0.408643523989;HOX{A6,A7,B6,B7}:-0.413266238891;MYFfamily:-0.445696575443;NFKB1_REL_RELA:-0.450120575037;ARID5B:-0.464841783202;NFE2L1:-0.467706934291;FOSL2:-0.475619812774;NKX2-1,4:-0.498317279455;CEBPA,B_DDIT3:-0.506759804437;MED-1{core}:-0.508329765679;TFCP2:-0.538380624966;SPI1:-0.545232042978;NANOG{mouse}:-0.564042125379;TLX2:-0.564196908412;FOX{D1,D2}:-0.569607206775;SOX5:-0.575936480827;MTE{core}:-0.580229115618;HSF1,2:-0.589972767965;PRDM1:-0.596450205878;HLF:-0.605218234584;XBP1:-0.622176506704;NHLH1,2:-0.657627639327;SPIB:-0.663737295476;ETS1,2:-0.691332039514;MEF2{A,B,C,D}:-0.695900212681;JUN:-0.721216318965;ATF6:-0.770597860093;PAX5:-0.813858132219;PDX1:-0.817892866303;PAX4:-0.835465106934;RUNX1..3:-0.837889869714;GTF2A1,2:-0.854103393985;RFX1:-0.892803779833;NR1H4:-0.901292931074;ELF1,2,4:-0.902245814212;POU6F1:-0.902314150408;NKX6-1,2:-0.925820676016;AR:-0.934459646668;RXR{A,B,G}:-0.935859893;NKX3-2:-0.94226273675;MAFB:-0.955490620888;DMAP1_NCOR{1,2}_SMARC:-0.978231347372;HMGA1,2:-0.983333550455;NFIX:-0.985301915242;ESR1:-0.997358336693;ZNF238:-1.00843042941;RFX2..5_RFXANK_RFXAP:-1.01057091741;TLX1..3_NFIC{dimer}:-1.02061124986;TGIF1:-1.02462510493;FOXP3:-1.03476225537;HOXA9_MEIS1:-1.04356897611;NR3C1:-1.07611313696;NFIL3:-1.08336800698;HES1:-1.08432838226;IRF7:-1.10435283413;AHR_ARNT_ARNT2:-1.14600521959;TAL1_TCF{3,4,12}:-1.20099105639;EP300:-1.20330568492;NFATC1..3:-1.24749797507;HMX1:-1.28482176142;BPTF:-1.34519526294;PAX6:-1.35412111025;ALX4:-1.3577427645;PAX3,7:-1.39974909163;NKX3-1:-1.40092543556;NKX2-2,8:-1.40491091647;IRF1,2:-1.40569341199;STAT2,4,6:-1.52984977573;HBP1_HMGB_SSRP1_UBTF:-1.55300863557;DBP:-1.55652963533;GLI1..3:-1.67394527985;RXRA_VDR{dimer}:-1.87221839751;SMAD1..7,9:-2.15354557404 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10786-110H3;search_select_hide=table117:FF:10786-110H3 | |||
}} | }} |
Latest revision as of 15:04, 3 June 2020
Name: | testicular germ cell embryonal carcinoma cell line:ITO-II |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11876 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11876
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11876
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.127 |
10 | 10 | 0.164 |
100 | 100 | 0.501 |
101 | 101 | 0.842 |
102 | 102 | 0.225 |
103 | 103 | 0.0113 |
104 | 104 | 0.791 |
105 | 105 | 0.334 |
106 | 106 | 0.0783 |
107 | 107 | 0.736 |
108 | 108 | 0.469 |
109 | 109 | 0.437 |
11 | 11 | 0.31 |
110 | 110 | 0.128 |
111 | 111 | 0.0432 |
112 | 112 | 0.345 |
113 | 113 | 0.101 |
114 | 114 | 0.0252 |
115 | 115 | 0.979 |
116 | 116 | 0.83 |
117 | 117 | 0.426 |
118 | 118 | 0.596 |
119 | 119 | 0.257 |
12 | 12 | 0.833 |
120 | 120 | 0.318 |
121 | 121 | 0.847 |
122 | 122 | 0.988 |
123 | 123 | 0.281 |
124 | 124 | 0.101 |
125 | 125 | 0.906 |
126 | 126 | 0.616 |
127 | 127 | 0.213 |
128 | 128 | 0.667 |
129 | 129 | 0.345 |
13 | 13 | 0.749 |
130 | 130 | 0.765 |
131 | 131 | 0.732 |
132 | 132 | 0.499 |
133 | 133 | 5.95488e-4 |
134 | 134 | 0.168 |
135 | 135 | 5.12793e-4 |
136 | 136 | 0.0427 |
137 | 137 | 0.451 |
138 | 138 | 0.0534 |
139 | 139 | 0.0889 |
14 | 14 | 0.909 |
140 | 140 | 0.363 |
141 | 141 | 0.575 |
142 | 142 | 0.534 |
143 | 143 | 0.00353 |
144 | 144 | 0.52 |
145 | 145 | 0.178 |
146 | 146 | 0.311 |
147 | 147 | 0.661 |
148 | 148 | 0.0312 |
149 | 149 | 0.00289 |
15 | 15 | 0.0895 |
150 | 150 | 0.946 |
151 | 151 | 0.0708 |
152 | 152 | 0.347 |
153 | 153 | 0.528 |
154 | 154 | 0.805 |
155 | 155 | 0.389 |
156 | 156 | 0.0459 |
157 | 157 | 0.749 |
158 | 158 | 0.656 |
159 | 159 | 0.339 |
16 | 16 | 0.335 |
160 | 160 | 0.319 |
161 | 161 | 0.242 |
162 | 162 | 0.437 |
163 | 163 | 0.515 |
164 | 164 | 0.787 |
165 | 165 | 0.693 |
166 | 166 | 0.19 |
167 | 167 | 0.361 |
168 | 168 | 0.522 |
169 | 169 | 0.209 |
17 | 17 | 0.72 |
18 | 18 | 0.55 |
19 | 19 | 0.0939 |
2 | 2 | 0.741 |
20 | 20 | 0.965 |
21 | 21 | 0.759 |
22 | 22 | 0.253 |
23 | 23 | 0.0312 |
24 | 24 | 0.556 |
25 | 25 | 0.645 |
26 | 26 | 0.662 |
27 | 27 | 0.616 |
28 | 28 | 0.808 |
29 | 29 | 0.504 |
3 | 3 | 0.0689 |
30 | 30 | 0.751 |
31 | 31 | 0.553 |
32 | 32 | 0.0121 |
33 | 33 | 0.887 |
34 | 34 | 0.712 |
35 | 35 | 0.246 |
36 | 36 | 0.599 |
37 | 37 | 0.417 |
38 | 38 | 0.59 |
39 | 39 | 0.509 |
4 | 4 | 0.85 |
40 | 40 | 0.755 |
41 | 41 | 0.301 |
42 | 42 | 0.403 |
43 | 43 | 0.0932 |
44 | 44 | 0.837 |
45 | 45 | 0.833 |
46 | 46 | 0.119 |
47 | 47 | 0.387 |
48 | 48 | 0.962 |
49 | 49 | 0.146 |
5 | 5 | 0.0814 |
50 | 50 | 0.488 |
51 | 51 | 0.972 |
52 | 52 | 0.87 |
53 | 53 | 0.402 |
54 | 54 | 0.809 |
55 | 55 | 0.109 |
56 | 56 | 0.993 |
57 | 57 | 0.861 |
58 | 58 | 0.0668 |
59 | 59 | 0.359 |
6 | 6 | 0.721 |
60 | 60 | 0.262 |
61 | 61 | 0.402 |
62 | 62 | 0.0249 |
63 | 63 | 0.243 |
64 | 64 | 0.538 |
65 | 65 | 0.191 |
66 | 66 | 0.571 |
67 | 67 | 0.733 |
68 | 68 | 0.277 |
69 | 69 | 0.34 |
7 | 7 | 0.899 |
70 | 70 | 0.0295 |
71 | 71 | 0.0355 |
72 | 72 | 0.519 |
73 | 73 | 0.695 |
74 | 74 | 0.0914 |
75 | 75 | 0.302 |
76 | 76 | 0.936 |
77 | 77 | 0.39 |
78 | 78 | 0.994 |
79 | 79 | 0.0528 |
8 | 8 | 0.116 |
80 | 80 | 0.0714 |
81 | 81 | 0.177 |
82 | 82 | 0.0776 |
83 | 83 | 0.0919 |
84 | 84 | 0.932 |
85 | 85 | 0.21 |
86 | 86 | 0.689 |
87 | 87 | 0.0212 |
88 | 88 | 0.149 |
89 | 89 | 0.112 |
9 | 9 | 0.107 |
90 | 90 | 0.26 |
91 | 91 | 0.202 |
92 | 92 | 0.129 |
93 | 93 | 0.314 |
94 | 94 | 0.465 |
95 | 95 | 0.509 |
96 | 96 | 0.0438 |
97 | 97 | 0.953 |
98 | 98 | 0.265 |
99 | 99 | 0.435 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11876
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
CL:0000586 germ cell
DOID:3095 germ cell and embryonal cancer
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0100297 carcinoma cell line sample
FF:0101560 testicular cancer cell line sample
UBERON:0000922 embryo
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0000255 (eukaryotic cell)
0000039 (germ line cell)
0000586 (germ cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
193 (reproductive organ cancer)
3095 (germ cell and embryonal cancer)
305 (carcinoma)
2994 (germ cell cancer)
UBERON: Anatomy
0000468 (multi-cellular organism)
0000922 (embryo)
0000473 (testis)
0000991 (gonad)
0005156 (reproductive structure)
0000466 (immaterial anatomical entity)
0000062 (organ)
0004120 (mesoderm-derived structure)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000990 (reproductive system)
0002553 (anatomical cavity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0003135 (male reproductive organ)
0003133 (reproductive organ)
0002323 (body cavity)
0000464 (anatomical space)
0004458 (body cavity or lining)
0010317 (germ layer / neural crest derived structure)
0003101 (male organism)
0000079 (male reproductive system)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100297 (carcinoma cell line sample)
0101120 (epithelial cell line sample)
0101560 (testicular cancer cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
UBERON:0009117 (indifferent gonad)
UBERON:0002532 (epiblast (generic))
UBERON:0006603 (presumptive mesoderm)
UBERON:0005564 (gonad primordium)
UBERON:0010316 (germ layer / neural crest)