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Coexpression cluster:C1279

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Full id: C1279_CD14_Neutrophils_substantia_Eosinophils_optic_globus_thalamus



Phase1 CAGE Peaks

Hg19::chr6:163841233..163841239,+p@chr6:163841233..163841239
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Hg19::chr6:163848296..163848300,+p@chr6:163848296..163848300
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Hg19::chr6:163849791..163849795,+p20@QKI
Hg19::chr6:163910016..163910030,+p@chr6:163910016..163910030
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Hg19::chr6:163910203..163910206,+p@chr6:163910203..163910206
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Hg19::chr6:163924190..163924195,+p@chr6:163924190..163924195
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Hg19::chr6:163928513..163928551,+p1@BC044915


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0051028mRNA transport0.0280623258369638
GO:0050658RNA transport0.0280623258369638
GO:0051236establishment of RNA localization0.0280623258369638
GO:0050657nucleic acid transport0.0280623258369638
GO:0006403RNA localization0.0280623258369638
GO:0015931nucleobase, nucleoside, nucleotide and nucleic acid transport0.0280623258369638
GO:0006417regulation of translation0.036427057576828
GO:0031326regulation of cellular biosynthetic process0.036427057576828
GO:0009889regulation of biosynthetic process0.036427057576828
GO:0008380RNA splicing0.036427057576828
GO:0006397mRNA processing0.0401801483574708
GO:0016071mRNA metabolic process0.0461409395973154



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism2.02e-22115
neural tube8.17e-2057
neural rod8.17e-2057
future spinal cord8.17e-2057
neural keel8.17e-2057
hematopoietic system3.72e-17102
blood island3.72e-17102
bone element1.01e-1686
regional part of forebrain1.43e-1641
forebrain1.43e-1641
future forebrain1.43e-1641
anterior neural tube1.65e-1642
bone marrow1.65e-1680
central nervous system2.15e-1682
regional part of brain3.03e-1659
brain4.37e-1669
future brain4.37e-1669
gray matter2.03e-1534
brain grey matter2.03e-1534
hemolymphoid system3.33e-15112
skeletal element3.48e-15101
skeletal system3.48e-15101
telencephalon3.91e-1534
regional part of telencephalon9.46e-1533
cerebral hemisphere6.77e-1432
regional part of nervous system1.38e-1394
nervous system1.38e-1394
neurectoderm1.22e-1290
neural plate2.74e-1286
presumptive neural plate2.74e-1286
immune system1.64e-11115
cerebral cortex2.23e-1025
pallium2.23e-1025
regional part of cerebral cortex5.78e-0922
pre-chordal neural plate1.17e-0861
anterior region of body5.94e-08129
craniocervical region5.94e-08129
head6.19e-08123
neocortex8.81e-0820
nucleus of brain9.84e-079
neural nucleus9.84e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.