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Coexpression cluster:C2607

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Full id: C2607_Neutrophils_medial_Monocytederived_CD14_amygdala_renal_occipital



Phase1 CAGE Peaks

Hg19::chr20:1905446..1905489,+p@chr20:1905446..1905489
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Hg19::chr20:1918006..1918018,+p@chr20:1918006..1918018
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Hg19::chr20:1918344..1918376,+p9@SIRPA
Hg19::chr22:30939618..30939629,+p@chr22:30939618..30939629
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube2.19e-1457
neural rod2.19e-1457
future spinal cord2.19e-1457
neural keel2.19e-1457
adult organism2.45e-13115
multi-cellular organism8.91e-13659
telencephalon2.30e-1234
regional part of forebrain3.73e-1241
forebrain3.73e-1241
future forebrain3.73e-1241
anterior neural tube4.87e-1242
gray matter5.00e-1234
brain grey matter5.00e-1234
regional part of telencephalon6.82e-1233
anatomical system6.84e-12625
hemolymphoid system1.04e-11112
anatomical group1.06e-11626
cerebral hemisphere1.12e-1132
bone marrow2.71e-1180
regional part of brain1.17e-1059
hematopoietic system1.69e-10102
blood island1.69e-10102
neurectoderm4.77e-1090
immune system7.26e-10115
regional part of cerebral cortex1.24e-0922
neural plate1.55e-0986
presumptive neural plate1.55e-0986
germ layer2.72e-09604
embryonic tissue2.72e-09604
presumptive structure2.72e-09604
epiblast (generic)2.72e-09604
bone element3.51e-0986
embryonic structure3.63e-09605
developing anatomical structure3.63e-09605
cerebral cortex3.88e-0925
pallium3.88e-0925
brain5.77e-0969
future brain5.77e-0969
embryo8.22e-09612
skeletal element8.45e-09101
skeletal system8.45e-09101
neocortex9.84e-0920
central nervous system1.50e-0882
lateral plate mesoderm2.52e-08216
anatomical conduit2.71e-07241
pre-chordal neural plate2.84e-0761
organ2.96e-07511
musculoskeletal system3.27e-07167
tube9.24e-07194


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.