FF:10820-111C1: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet=UBERON: | |DRA_sample_Accession=CAGE@SAMD00005359 | ||
| | |accession_numbers=CAGE;DRX007907;DRR008779;DRZ000204;DRZ001589;DRZ011554;DRZ012939 | ||
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002107,UBERON:0002100,UBERON:0001007,UBERON:0004119,UBERON:0000062,UBERON:0000475,UBERON:0000061,UBERON:0000465,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0009569,UBERON:0002368,UBERON:0005177,UBERON:0002365,UBERON:0005172,UBERON:0006925,UBERON:0002530,UBERON:0010317,UBERON:0005173,UBERON:0002417,UBERON:0000949,UBERON:0002330,UBERON:0000916,UBERON:0002423 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0002371,CL:0000181,CL:0000417,CL:0000668,CL:0000412,CL:0000255,CL:0000182 | |||
|ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:7,DOID:305 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100297,FF:0101120,FF:0100224,FF:0100578,FF:0100599 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score | |||
|fonse_cell_line=FF:0100224,FF:0101120 | |fonse_cell_line=FF:0100224,FF:0101120 | ||
|fonse_cell_line_closure=FF:0100224,FF:0101120 | |fonse_cell_line_closure=FF:0100224,FF:0101120 | ||
| Line 35: | Line 41: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/hepatocellular%2520carcinoma%2520cell%2520line%253a%2520HepG2%2520ENCODE%252c%2520biol_rep3.CNhs12330.10820-111C1.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/hepatocellular%2520carcinoma%2520cell%2520line%253a%2520HepG2%2520ENCODE%252c%2520biol_rep3.CNhs12330.10820-111C1.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/hepatocellular%2520carcinoma%2520cell%2520line%253a%2520HepG2%2520ENCODE%252c%2520biol_rep3.CNhs12330.10820-111C1.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/hepatocellular%2520carcinoma%2520cell%2520line%253a%2520HepG2%2520ENCODE%252c%2520biol_rep3.CNhs12330.10820-111C1.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/hepatocellular%2520carcinoma%2520cell%2520line%253a%2520HepG2%2520ENCODE%252c%2520biol_rep3.CNhs12330.10820-111C1.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10820-111C1 | |id=FF:10820-111C1 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0000210;;FF:0100599 | ||
|is_obsolete= | |||
|library_id=CNhs12330 | |||
|library_id_phase_based=2:CNhs12330 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10820 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10820 | |||
|name=hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep3 | |name=hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep3 | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
| Line 42: | Line 60: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs12330,LSID913,release011,COMPLETED | |profile_hcage=CNhs12330,LSID913,release011,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0.0122527892228596,0,0,0,-0.0128206339669567,0.0549220396220714,-0.219911258584019,0.236703834502645,0,0,0,0.0115170932302193,0,0,0,0,0,0,0,0,0,-0.0271858474165909,0,0,0,0,0,0.089345157709168,0,0,0.0145408063405671,0,0,0,0,0,0,0,0,0,0,0.0549220396220714,0,-0.107247688635478,0.0914225704117884,0,0,0,0,0,0,0,0.162671230277851,0,0,0,0.0283286403579212,0,0,0.0549220396220714,0.248040817457688,0,0,-0.0690149868551758,0,0,0,0,0,0,0,0,0.0549220396220714,0,0,0,0,0,0,0,0,0,0.272027278014621,0,0.0175307729422219,0,0,0,0.180792459278583,0,0,0,0.304152433199969,-0.145197201151192,0,0,0.0141643201789606,0.0283286403579212,0.0698207672622482,0.162990015069682,0,0,0,0,0,0,0.0283286403579212,0,0,0,0.593184549984491,0,0,0,0,0,0,-0.0058439926455069,0.331601434044009,0,0,-0.0351412406717597,-0.166701634118496,0,0,0.0536890835444736,0,0,0 | |||
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|rna_box=111 | |rna_box=111 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
| Line 57: | Line 78: | ||
|rna_weight_ug=57.042 | |rna_weight_ug=57.042 | ||
|sample_age=15 | |sample_age=15 | ||
|sample_category=cell lines | |||
|sample_cell_catalog= | |sample_cell_catalog= | ||
|sample_cell_line=HepG2 | |sample_cell_line=HepG2 | ||
| Line 69: | Line 91: | ||
|sample_ethnicity= | |sample_ethnicity= | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;8.22891671032135e-267!GO:0043231;intracellular membrane-bound organelle;2.89161449432492e-224!GO:0043227;membrane-bound organelle;3.35878834646412e-224!GO:0043226;organelle;9.76908906956293e-220!GO:0043229;intracellular organelle;3.21745434271779e-219!GO:0005737;cytoplasm;3.93092958672489e-190!GO:0044422;organelle part;6.07559332870528e-159!GO:0044446;intracellular organelle part;2.01085934028132e-157!GO:0044444;cytoplasmic part;2.18882768541232e-140!GO:0044237;cellular metabolic process;1.15226081573549e-117!GO:0044238;primary metabolic process;1.86957340360491e-115!GO:0032991;macromolecular complex;9.48312883434434e-106!GO:0043170;macromolecule metabolic process;4.90730505687799e-92!GO:0005634;nucleus;4.90730505687799e-92!GO:0030529;ribonucleoprotein complex;7.71954652745134e-92!GO:0043233;organelle lumen;7.78778167949409e-90!GO:0031974;membrane-enclosed lumen;7.78778167949409e-90!GO:0044428;nuclear part;1.41764887602459e-85!GO:0005739;mitochondrion;1.57655470566646e-84!GO:0003723;RNA binding;7.76909443672507e-84!GO:0006396;RNA processing;4.29326626184761e-58!GO:0005515;protein binding;9.13589547182504e-58!GO:0044429;mitochondrial part;1.65659108839397e-53!GO:0031981;nuclear lumen;2.49968993303223e-53!GO:0005840;ribosome;1.24465997842989e-52!GO:0043234;protein complex;1.54583788926495e-52!GO:0006412;translation;1.03886297664481e-50!GO:0031090;organelle membrane;1.937207637195e-49!GO:0009058;biosynthetic process;3.5299991347975e-49!GO:0019538;protein metabolic process;2.59832839128496e-48!GO:0043283;biopolymer metabolic process;5.13791650269924e-47!GO:0044249;cellular biosynthetic process;3.90909707136601e-46!GO:0031967;organelle envelope;3.38637595396619e-45!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;6.77523728349964e-45!GO:0016071;mRNA metabolic process;7.71688137891557e-45!GO:0031975;envelope;8.54812015403984e-45!GO:0010467;gene expression;5.15315431033663e-44!GO:0003735;structural constituent of ribosome;1.04722736527192e-43!GO:0044267;cellular protein metabolic process;8.99789671154329e-43!GO:0044260;cellular macromolecule metabolic process;1.19640278395908e-42!GO:0016043;cellular component organization and biogenesis;8.72575345347827e-42!GO:0009059;macromolecule biosynthetic process;1.25728810104229e-41!GO:0008380;RNA splicing;1.61707848490191e-40!GO:0015031;protein transport;6.58164423291765e-40!GO:0033036;macromolecule localization;5.12166636990469e-39!GO:0033279;ribosomal subunit;4.29273815532632e-38!GO:0006259;DNA metabolic process;7.71121124690602e-38!GO:0006397;mRNA processing;1.21556275879301e-37!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.30376485563054e-36!GO:0005829;cytosol;2.29328599339713e-36!GO:0045184;establishment of protein localization;9.08709711286152e-36!GO:0065003;macromolecular complex assembly;2.1518671288581e-35!GO:0008104;protein localization;7.32038594015792e-35!GO:0046907;intracellular transport;5.88948179906251e-34!GO:0043228;non-membrane-bound organelle;1.12922632228598e-33!GO:0043232;intracellular non-membrane-bound organelle;1.12922632228598e-33!GO:0005654;nucleoplasm;1.42382389191052e-32!GO:0005740;mitochondrial envelope;1.10764496329925e-31!GO:0003676;nucleic acid binding;1.9674504381111e-31!GO:0006996;organelle organization and biogenesis;3.25894519351988e-31!GO:0022607;cellular component assembly;5.63537828822282e-31!GO:0019866;organelle inner membrane;1.33122567577404e-30!GO:0031966;mitochondrial membrane;2.22097609118574e-29!GO:0007049;cell cycle;3.06434690847869e-29!GO:0005681;spliceosome;2.01085066172287e-28!GO:0006886;intracellular protein transport;3.34753227961123e-28!GO:0005743;mitochondrial inner membrane;1.62833629189393e-27!GO:0005830;cytosolic ribosome (sensu Eukaryota);4.15706361363523e-27!GO:0031980;mitochondrial lumen;2.62862708539208e-26!GO:0005759;mitochondrial matrix;2.62862708539208e-26!GO:0044451;nucleoplasm part;3.80605399284889e-26!GO:0000166;nucleotide binding;9.51532517880913e-25!GO:0006974;response to DNA damage stimulus;8.94724790627702e-24!GO:0000278;mitotic cell cycle;1.19927696289343e-23!GO:0005783;endoplasmic reticulum;1.22729628819875e-23!GO:0044248;cellular catabolic process;1.70177978370702e-23!GO:0016874;ligase activity;6.51401736569284e-22!GO:0044445;cytosolic part;8.47205297730483e-22!GO:0051649;establishment of cellular localization;1.7381708098019e-21!GO:0051641;cellular localization;1.79036396008959e-21!GO:0022402;cell cycle process;1.88615981963022e-21!GO:0015935;small ribosomal subunit;6.66597175951458e-21!GO:0005694;chromosome;7.07387129181826e-21!GO:0016070;RNA metabolic process;9.210539764867e-21!GO:0006119;oxidative phosphorylation;9.79157520420627e-21!GO:0006457;protein folding;1.35385011224693e-20!GO:0005730;nucleolus;1.4011144250936e-20!GO:0022618;protein-RNA complex assembly;5.48620417233453e-20!GO:0000087;M phase of mitotic cell cycle;1.9525024185225e-19!GO:0012505;endomembrane system;2.0214007870086e-19!GO:0006281;DNA repair;2.22301829931292e-19!GO:0051186;cofactor metabolic process;2.70884146341991e-19!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;4.13368660549175e-19!GO:0016462;pyrophosphatase activity;4.54093602770946e-19!GO:0007067;mitosis;4.93969219502751e-19!GO:0044432;endoplasmic reticulum part;5.19514582604481e-19!GO:0044265;cellular macromolecule catabolic process;5.50208177321156e-19!GO:0016817;hydrolase activity, acting on acid anhydrides;5.72306571306523e-19!GO:0044455;mitochondrial membrane part;6.38671803214266e-19!GO:0017111;nucleoside-triphosphatase activity;9.09653715516198e-19!GO:0044427;chromosomal part;1.40719901765471e-18!GO:0015934;large ribosomal subunit;2.67990503436557e-18!GO:0051276;chromosome organization and biogenesis;6.92382978124728e-18!GO:0009719;response to endogenous stimulus;1.99360403547022e-17!GO:0042254;ribosome biogenesis and assembly;2.08376843740689e-17!GO:0051301;cell division;2.56279773129299e-17!GO:0006512;ubiquitin cycle;3.47570069490145e-17!GO:0008135;translation factor activity, nucleic acid binding;6.37219154570781e-17!GO:0043285;biopolymer catabolic process;6.47980640578005e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;6.62191185320338e-17!GO:0022403;cell cycle phase;1.07604603088818e-16!GO:0006260;DNA replication;1.40161278872837e-16!GO:0019941;modification-dependent protein catabolic process;1.56885872219661e-16!GO:0043632;modification-dependent macromolecule catabolic process;1.56885872219661e-16!GO:0006511;ubiquitin-dependent protein catabolic process;1.87620002362181e-16!GO:0044257;cellular protein catabolic process;2.04426679260743e-16!GO:0017076;purine nucleotide binding;2.77134239248832e-16!GO:0005524;ATP binding;2.93253878768914e-16!GO:0030554;adenyl nucleotide binding;4.89624701996463e-16!GO:0042623;ATPase activity, coupled;5.60139782500914e-16!GO:0016887;ATPase activity;5.68518443039483e-16!GO:0006732;coenzyme metabolic process;6.99036117129706e-16!GO:0000502;proteasome complex (sensu Eukaryota);8.62733137001986e-16!GO:0032553;ribonucleotide binding;8.82821867904622e-16!GO:0032555;purine ribonucleotide binding;8.82821867904622e-16!GO:0009057;macromolecule catabolic process;9.64228782453881e-16!GO:0005746;mitochondrial respiratory chain;9.70394603798358e-16!GO:0032559;adenyl ribonucleotide binding;9.94154365452115e-16!GO:0005761;mitochondrial ribosome;1.57040372845743e-15!GO:0000313;organellar ribosome;1.57040372845743e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.74407064221875e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.03840350695673e-15!GO:0009056;catabolic process;3.17228828583016e-15!GO:0048770;pigment granule;5.51952699769233e-15!GO:0042470;melanosome;5.51952699769233e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;6.9689698871075e-15!GO:0000375;RNA splicing, via transesterification reactions;6.9689698871075e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;6.9689698871075e-15!GO:0000279;M phase;1.04133745673175e-14!GO:0008134;transcription factor binding;1.25812063784236e-14!GO:0044453;nuclear membrane part;1.29506902158029e-14!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.48832288352834e-14!GO:0004386;helicase activity;2.23245114079247e-14!GO:0050136;NADH dehydrogenase (quinone) activity;2.26067577329715e-14!GO:0003954;NADH dehydrogenase activity;2.26067577329715e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.26067577329715e-14!GO:0005789;endoplasmic reticulum membrane;3.46544612264006e-14!GO:0031965;nuclear membrane;4.34493695607237e-14!GO:0005635;nuclear envelope;7.09278531268731e-14!GO:0051082;unfolded protein binding;8.98926680470548e-14!GO:0006605;protein targeting;9.07639648821304e-14!GO:0006325;establishment and/or maintenance of chromatin architecture;1.76800762001057e-13!GO:0006323;DNA packaging;2.97565635299785e-13!GO:0030163;protein catabolic process;3.63846171099509e-13!GO:0003743;translation initiation factor activity;6.62880686851181e-13!GO:0016604;nuclear body;8.74163725730025e-13!GO:0005643;nuclear pore;9.84456936412394e-13!GO:0009055;electron carrier activity;1.24020681508221e-12!GO:0042775;organelle ATP synthesis coupled electron transport;1.40807049654052e-12!GO:0042773;ATP synthesis coupled electron transport;1.40807049654052e-12!GO:0006082;organic acid metabolic process;1.45163230099815e-12!GO:0019752;carboxylic acid metabolic process;1.73668700926717e-12!GO:0006413;translational initiation;1.86450591138133e-12!GO:0030964;NADH dehydrogenase complex (quinone);2.27946984638493e-12!GO:0045271;respiratory chain complex I;2.27946984638493e-12!GO:0005747;mitochondrial respiratory chain complex I;2.27946984638493e-12!GO:0050657;nucleic acid transport;2.40000546794751e-12!GO:0051236;establishment of RNA localization;2.40000546794751e-12!GO:0050658;RNA transport;2.40000546794751e-12!GO:0046930;pore complex;2.84261458987314e-12!GO:0006403;RNA localization;3.95753360469193e-12!GO:0006399;tRNA metabolic process;4.53528147089027e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;6.00611257602453e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);6.28891852547525e-12!GO:0048193;Golgi vesicle transport;9.24539251507693e-12!GO:0006364;rRNA processing;1.05642080290626e-11!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.19209662392882e-11!GO:0008026;ATP-dependent helicase activity;1.76624100162443e-11!GO:0016072;rRNA metabolic process;2.64804222572002e-11!GO:0016491;oxidoreductase activity;2.74081949177907e-11!GO:0006913;nucleocytoplasmic transport;4.71830378780251e-11!GO:0065002;intracellular protein transport across a membrane;4.82558746379939e-11!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;4.92603201685802e-11!GO:0006461;protein complex assembly;5.19268439805079e-11!GO:0005793;ER-Golgi intermediate compartment;5.25617541256632e-11!GO:0043412;biopolymer modification;5.65291671980232e-11!GO:0016879;ligase activity, forming carbon-nitrogen bonds;9.66796063491011e-11!GO:0051169;nuclear transport;1.31667411492197e-10!GO:0006446;regulation of translational initiation;1.40417296110112e-10!GO:0051726;regulation of cell cycle;1.6630257799654e-10!GO:0016607;nuclear speck;1.927173579573e-10!GO:0051028;mRNA transport;2.49827839389411e-10!GO:0000074;regulation of progression through cell cycle;2.55026597802665e-10!GO:0000785;chromatin;2.55026597802665e-10!GO:0006333;chromatin assembly or disassembly;8.94433999271355e-10!GO:0008565;protein transporter activity;1.33518903305026e-09!GO:0008639;small protein conjugating enzyme activity;1.57148125048337e-09!GO:0016192;vesicle-mediated transport;1.71996790807066e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.73690246084775e-09!GO:0004812;aminoacyl-tRNA ligase activity;1.73690246084775e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.73690246084775e-09!GO:0005794;Golgi apparatus;2.18360919606047e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.33944475578448e-09!GO:0003712;transcription cofactor activity;2.41144396230444e-09!GO:0004842;ubiquitin-protein ligase activity;2.51033717987694e-09!GO:0065004;protein-DNA complex assembly;3.34579806416164e-09!GO:0019787;small conjugating protein ligase activity;3.37535069301292e-09!GO:0009259;ribonucleotide metabolic process;3.52112470183664e-09!GO:0006163;purine nucleotide metabolic process;3.55606215537552e-09!GO:0006915;apoptosis;3.61612387198653e-09!GO:0016740;transferase activity;3.63153643453645e-09!GO:0012501;programmed cell death;3.70307048484449e-09!GO:0043038;amino acid activation;5.01847203924066e-09!GO:0006418;tRNA aminoacylation for protein translation;5.01847203924066e-09!GO:0043039;tRNA aminoacylation;5.01847203924066e-09!GO:0006464;protein modification process;5.04300191275619e-09!GO:0016568;chromatin modification;5.3958795657625e-09!GO:0006366;transcription from RNA polymerase II promoter;6.61442159463157e-09!GO:0030532;small nuclear ribonucleoprotein complex;8.11604211793616e-09!GO:0016779;nucleotidyltransferase activity;1.19441436916319e-08!GO:0016787;hydrolase activity;2.4303799630846e-08!GO:0008219;cell death;2.44938350581992e-08!GO:0016265;death;2.44938350581992e-08!GO:0006888;ER to Golgi vesicle-mediated transport;3.1411655715181e-08!GO:0009150;purine ribonucleotide metabolic process;3.51898819986775e-08!GO:0006752;group transfer coenzyme metabolic process;3.5351658442536e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;3.68956593919335e-08!GO:0006091;generation of precursor metabolites and energy;4.00522574847603e-08!GO:0006164;purine nucleotide biosynthetic process;4.07975967382383e-08!GO:0016881;acid-amino acid ligase activity;4.25693479981918e-08!GO:0051188;cofactor biosynthetic process;4.49964077194363e-08!GO:0045333;cellular respiration;4.74896074010072e-08!GO:0006261;DNA-dependent DNA replication;4.89498466607843e-08!GO:0017038;protein import;4.89498466607843e-08!GO:0009060;aerobic respiration;5.19550765633381e-08!GO:0032446;protein modification by small protein conjugation;5.51035881936274e-08!GO:0005667;transcription factor complex;6.62719471768127e-08!GO:0009260;ribonucleotide biosynthetic process;8.71003590140738e-08!GO:0005819;spindle;9.75819151824584e-08!GO:0016567;protein ubiquitination;1.03042743201962e-07!GO:0051187;cofactor catabolic process;1.25853390037585e-07!GO:0000775;chromosome, pericentric region;1.31036078734979e-07!GO:0043566;structure-specific DNA binding;1.35660321389934e-07!GO:0015986;ATP synthesis coupled proton transport;1.54872645837451e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.54872645837451e-07!GO:0006520;amino acid metabolic process;1.58276868133887e-07!GO:0043687;post-translational protein modification;1.76660097038198e-07!GO:0000245;spliceosome assembly;2.00476745575408e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.48252156753985e-07!GO:0005768;endosome;3.0744120652464e-07!GO:0009199;ribonucleoside triphosphate metabolic process;3.15620941962894e-07!GO:0044255;cellular lipid metabolic process;3.18035548877455e-07!GO:0009152;purine ribonucleotide biosynthetic process;3.83846200185305e-07!GO:0003697;single-stranded DNA binding;4.03740446111563e-07!GO:0009141;nucleoside triphosphate metabolic process;4.20547608970187e-07!GO:0046034;ATP metabolic process;4.21669275887228e-07!GO:0009108;coenzyme biosynthetic process;4.2362644982196e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;5.45919621334377e-07!GO:0009144;purine nucleoside triphosphate metabolic process;5.45919621334377e-07!GO:0006099;tricarboxylic acid cycle;5.94533092406791e-07!GO:0046356;acetyl-CoA catabolic process;5.94533092406791e-07!GO:0016469;proton-transporting two-sector ATPase complex;6.41865038695748e-07!GO:0006334;nucleosome assembly;6.57053150419539e-07!GO:0019829;cation-transporting ATPase activity;7.6536016524361e-07!GO:0016853;isomerase activity;7.73377821338385e-07!GO:0015630;microtubule cytoskeleton;8.51773614388377e-07!GO:0045259;proton-transporting ATP synthase complex;8.69271592297709e-07!GO:0006084;acetyl-CoA metabolic process;8.88020534960753e-07!GO:0008094;DNA-dependent ATPase activity;9.25290620842461e-07!GO:0007051;spindle organization and biogenesis;9.55687595124788e-07!GO:0006950;response to stress;9.56350669618922e-07!GO:0007005;mitochondrion organization and biogenesis;1.04696616914104e-06!GO:0051329;interphase of mitotic cell cycle;1.17681738370696e-06!GO:0015078;hydrogen ion transmembrane transporter activity;1.2372133825333e-06!GO:0000151;ubiquitin ligase complex;1.40063933513121e-06!GO:0009142;nucleoside triphosphate biosynthetic process;1.40192382960316e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.40192382960316e-06!GO:0042981;regulation of apoptosis;1.45405914886109e-06!GO:0031497;chromatin assembly;1.51022438285338e-06!GO:0006754;ATP biosynthetic process;1.51022438285338e-06!GO:0006753;nucleoside phosphate metabolic process;1.51022438285338e-06!GO:0005788;endoplasmic reticulum lumen;1.63207087853927e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.6468060260856e-06!GO:0005813;centrosome;1.78469027485534e-06!GO:0006807;nitrogen compound metabolic process;1.78469027485534e-06!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.84398036923671e-06!GO:0003899;DNA-directed RNA polymerase activity;1.86077062529331e-06!GO:0043623;cellular protein complex assembly;1.89791526800833e-06!GO:0003724;RNA helicase activity;2.01071343850789e-06!GO:0009308;amine metabolic process;2.15333071218439e-06!GO:0043067;regulation of programmed cell death;2.18874945673608e-06!GO:0005815;microtubule organizing center;2.42912692192599e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.44744812145703e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.44744812145703e-06!GO:0006519;amino acid and derivative metabolic process;2.52438271503504e-06!GO:0005657;replication fork;2.64001491155886e-06!GO:0009109;coenzyme catabolic process;2.74047406892972e-06!GO:0051246;regulation of protein metabolic process;3.31882399405031e-06!GO:0005839;proteasome core complex (sensu Eukaryota);4.03149726318107e-06!GO:0051168;nuclear export;4.50140868786473e-06!GO:0016741;transferase activity, transferring one-carbon groups;4.88506408181462e-06!GO:0003713;transcription coactivator activity;4.96971931682811e-06!GO:0048037;cofactor binding;5.16204593634427e-06!GO:0016363;nuclear matrix;5.28166633295758e-06!GO:0008168;methyltransferase activity;6.12846153973897e-06!GO:0000075;cell cycle checkpoint;6.76232390860259e-06!GO:0006613;cotranslational protein targeting to membrane;7.04999187905562e-06!GO:0005762;mitochondrial large ribosomal subunit;9.79808498738061e-06!GO:0000315;organellar large ribosomal subunit;9.79808498738061e-06!GO:0016125;sterol metabolic process;1.096722130985e-05!GO:0016563;transcription activator activity;1.20088937437258e-05!GO:0030120;vesicle coat;1.44355336440194e-05!GO:0030662;coated vesicle membrane;1.44355336440194e-05!GO:0009117;nucleotide metabolic process;1.4597830775806e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;1.46456640871522e-05!GO:0051325;interphase;1.46532705677213e-05!GO:0006629;lipid metabolic process;1.61674756734601e-05!GO:0004298;threonine endopeptidase activity;1.64713832547631e-05!GO:0048475;coated membrane;1.70766333693982e-05!GO:0030117;membrane coat;1.70766333693982e-05!GO:0044452;nucleolar part;1.86525793641868e-05!GO:0046483;heterocycle metabolic process;2.03046643655483e-05!GO:0016859;cis-trans isomerase activity;2.19647940086414e-05!GO:0006302;double-strand break repair;2.85495427528548e-05!GO:0006401;RNA catabolic process;3.00558328643129e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;3.18397355538171e-05!GO:0043069;negative regulation of programmed cell death;3.53993252211632e-05!GO:0003690;double-stranded DNA binding;3.66305668873821e-05!GO:0006402;mRNA catabolic process;3.96888000795905e-05!GO:0051170;nuclear import;3.99898455407512e-05!GO:0043066;negative regulation of apoptosis;4.04187601984918e-05!GO:0031324;negative regulation of cellular metabolic process;4.09034228251543e-05!GO:0000314;organellar small ribosomal subunit;4.41384438659976e-05!GO:0005763;mitochondrial small ribosomal subunit;4.41384438659976e-05!GO:0005770;late endosome;4.59293452765384e-05!GO:0006606;protein import into nucleus;4.68220825616832e-05!GO:0006066;alcohol metabolic process;4.95783317008133e-05!GO:0045454;cell redox homeostasis;5.43690017062905e-05!GO:0016126;sterol biosynthetic process;5.50676871360972e-05!GO:0015980;energy derivation by oxidation of organic compounds;5.73705722118048e-05!GO:0044440;endosomal part;6.26793993791951e-05!GO:0010008;endosome membrane;6.26793993791951e-05!GO:0044262;cellular carbohydrate metabolic process;6.26793993791951e-05!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;6.28203163003843e-05!GO:0051427;hormone receptor binding;8.10635961323901e-05!GO:0006695;cholesterol biosynthetic process;8.53494073442633e-05!GO:0016564;transcription repressor activity;8.57170448735122e-05!GO:0008654;phospholipid biosynthetic process;9.21726529123633e-05!GO:0008203;cholesterol metabolic process;9.27470970558929e-05!GO:0050662;coenzyme binding;9.88795028127925e-05!GO:0030880;RNA polymerase complex;0.000100232365742962!GO:0043021;ribonucleoprotein binding;0.00010209492160775!GO:0005798;Golgi-associated vesicle;0.00010425569319563!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.000115851786850302!GO:0019843;rRNA binding;0.000115851786850302!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000117899057719591!GO:0008186;RNA-dependent ATPase activity;0.000121210321683443!GO:0009892;negative regulation of metabolic process;0.000125248938369483!GO:0050794;regulation of cellular process;0.000132157375691882!GO:0007059;chromosome segregation;0.000135337283311318!GO:0000776;kinetochore;0.000137813382895931!GO:0030867;rough endoplasmic reticulum membrane;0.000140145472811495!GO:0008652;amino acid biosynthetic process;0.000140752348765536!GO:0051052;regulation of DNA metabolic process;0.000160684568687658!GO:0035257;nuclear hormone receptor binding;0.000166521328405873!GO:0008610;lipid biosynthetic process;0.000173882083742649!GO:0042802;identical protein binding;0.000183222664892781!GO:0045786;negative regulation of progression through cell cycle;0.000198180550726152!GO:0008033;tRNA processing;0.000208130170372021!GO:0003729;mRNA binding;0.000212776607993763!GO:0043681;protein import into mitochondrion;0.000234915918581515!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000235758899747102!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000249336843092959!GO:0000428;DNA-directed RNA polymerase complex;0.000249336843092959!GO:0003682;chromatin binding;0.000258918604169718!GO:0005048;signal sequence binding;0.000260637605708085!GO:0019899;enzyme binding;0.000280952336232687!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.000284244980760624!GO:0005791;rough endoplasmic reticulum;0.000289450589058231!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000320630174787701!GO:0015399;primary active transmembrane transporter activity;0.000320630174787701!GO:0031968;organelle outer membrane;0.000344237963533925!GO:0042157;lipoprotein metabolic process;0.000345210759714831!GO:0004004;ATP-dependent RNA helicase activity;0.000345261790843814!GO:0019867;outer membrane;0.000345960478258493!GO:0031988;membrane-bound vesicle;0.000366299929413357!GO:0003684;damaged DNA binding;0.000410458012285297!GO:0003714;transcription corepressor activity;0.000417705112408343!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.000440135970464085!GO:0006338;chromatin remodeling;0.000445841603682843!GO:0016023;cytoplasmic membrane-bound vesicle;0.000463849006314535!GO:0019222;regulation of metabolic process;0.000467017156476277!GO:0000786;nucleosome;0.000519399170716799!GO:0006612;protein targeting to membrane;0.000528373722189625!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000543598117889915!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00061158609709751!GO:0006414;translational elongation;0.000620087483702255!GO:0006352;transcription initiation;0.000628476478841785!GO:0007088;regulation of mitosis;0.000641035249070396!GO:0005741;mitochondrial outer membrane;0.00065187823157089!GO:0030134;ER to Golgi transport vesicle;0.000664403534651853!GO:0032508;DNA duplex unwinding;0.000685612838486205!GO:0032392;DNA geometric change;0.000685612838486205!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000705310564277452!GO:0006383;transcription from RNA polymerase III promoter;0.000720488894480743!GO:0000059;protein import into nucleus, docking;0.000803704120923198!GO:0051252;regulation of RNA metabolic process;0.000806236770942554!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000842413135873537!GO:0006916;anti-apoptosis;0.000852377846854014!GO:0032787;monocarboxylic acid metabolic process;0.00093439971794879!GO:0022890;inorganic cation transmembrane transporter activity;0.000949353478262546!GO:0044431;Golgi apparatus part;0.00100484936977415!GO:0051920;peroxiredoxin activity;0.00102845893996738!GO:0005769;early endosome;0.00103798768782376!GO:0016408;C-acyltransferase activity;0.00107589395370828!GO:0005684;U2-dependent spliceosome;0.00111453242809619!GO:0006626;protein targeting to mitochondrion;0.00113242325913251!GO:0031982;vesicle;0.00114541506665879!GO:0006839;mitochondrial transport;0.00119417638328029!GO:0048500;signal recognition particle;0.00120648755584865!GO:0006118;electron transport;0.00121990147701345!GO:0006595;polyamine metabolic process;0.00125784323213632!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.00130386618981888!GO:0030521;androgen receptor signaling pathway;0.00130660658837435!GO:0006268;DNA unwinding during replication;0.0013789432710267!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00140313998356964!GO:0007052;mitotic spindle organization and biogenesis;0.00140383364334414!GO:0048523;negative regulation of cellular process;0.00141761744069949!GO:0007093;mitotic cell cycle checkpoint;0.00143905199513669!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00148441335825275!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00148441335825275!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00148441335825275!GO:0000082;G1/S transition of mitotic cell cycle;0.0014980267324377!GO:0043284;biopolymer biosynthetic process;0.00150152158112493!GO:0006405;RNA export from nucleus;0.00151460646898197!GO:0042393;histone binding;0.00152610374397379!GO:0033116;ER-Golgi intermediate compartment membrane;0.00154257863134574!GO:0007006;mitochondrial membrane organization and biogenesis;0.00164302439103738!GO:0006793;phosphorus metabolic process;0.00169015752892185!GO:0006796;phosphate metabolic process;0.00169015752892185!GO:0031410;cytoplasmic vesicle;0.0017220334623822!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0017220334623822!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0017220334623822!GO:0051659;maintenance of mitochondrion localization;0.0017220334623822!GO:0051657;maintenance of organelle localization;0.0017220334623822!GO:0019439;aromatic compound catabolic process;0.00183319892232468!GO:0008139;nuclear localization sequence binding;0.00184915329599584!GO:0030127;COPII vesicle coat;0.00186101141575042!GO:0012507;ER to Golgi transport vesicle membrane;0.00186101141575042!GO:0051789;response to protein stimulus;0.00190579216719598!GO:0006986;response to unfolded protein;0.00190579216719598!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00192972311270781!GO:0003678;DNA helicase activity;0.00193350258775265!GO:0031072;heat shock protein binding;0.00194799238671053!GO:0003746;translation elongation factor activity;0.00198565380772174!GO:0042158;lipoprotein biosynthetic process;0.00201795072650809!GO:0005885;Arp2/3 protein complex;0.00207060529292092!GO:0009064;glutamine family amino acid metabolic process;0.00209433968431425!GO:0043492;ATPase activity, coupled to movement of substances;0.00217551122695681!GO:0004527;exonuclease activity;0.00219796535831044!GO:0000096;sulfur amino acid metabolic process;0.00232563031893622!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0023562452540198!GO:0005773;vacuole;0.00244635138343029!GO:0043488;regulation of mRNA stability;0.0024585441034463!GO:0043487;regulation of RNA stability;0.0024585441034463!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.00251599068835062!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00254684558280375!GO:0009063;amino acid catabolic process;0.00257974919526483!GO:0003711;transcription elongation regulator activity;0.00262947663518689!GO:0008022;protein C-terminus binding;0.00264441852105973!GO:0009303;rRNA transcription;0.00270252129612779!GO:0006611;protein export from nucleus;0.00270635315271047!GO:0016407;acetyltransferase activity;0.00272467841249251!GO:0005637;nuclear inner membrane;0.00276094412157108!GO:0008312;7S RNA binding;0.00283070975544937!GO:0005876;spindle microtubule;0.00283594580845933!GO:0000922;spindle pole;0.00290649390893818!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00298088176879801!GO:0006270;DNA replication initiation;0.00309014180562705!GO:0016746;transferase activity, transferring acyl groups;0.00309808842457529!GO:0047485;protein N-terminus binding;0.00310189259509095!GO:0016251;general RNA polymerase II transcription factor activity;0.00313089231977671!GO:0005777;peroxisome;0.00313089231977671!GO:0042579;microbody;0.00313089231977671!GO:0000819;sister chromatid segregation;0.00313089231977671!GO:0006818;hydrogen transport;0.00318081494203167!GO:0004518;nuclease activity;0.00321663095769177!GO:0005975;carbohydrate metabolic process;0.00327037501123913!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00330856607108535!GO:0048471;perinuclear region of cytoplasm;0.00335118717595282!GO:0016747;transferase activity, transferring groups other than amino-acyl groups;0.00337610163583385!GO:0000049;tRNA binding;0.00347190283861842!GO:0009165;nucleotide biosynthetic process;0.00355546793208037!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00356644427320801!GO:0045047;protein targeting to ER;0.00356644427320801!GO:0035258;steroid hormone receptor binding;0.00357556356360944!GO:0046474;glycerophospholipid biosynthetic process;0.00358059191839504!GO:0008202;steroid metabolic process;0.00377897411970415!GO:0051087;chaperone binding;0.00377983518998798!GO:0031124;mRNA 3'-end processing;0.00385596892965759!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.00389493005010325!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00394416795464622!GO:0030658;transport vesicle membrane;0.00395254180607393!GO:0000070;mitotic sister chromatid segregation;0.004045996290193!GO:0009451;RNA modification;0.00404948705466128!GO:0031252;leading edge;0.00405706650182352!GO:0015992;proton transport;0.0041209857539601!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.00418539304686114!GO:0008629;induction of apoptosis by intracellular signals;0.00421925295764704!GO:0006979;response to oxidative stress;0.00460921896844269!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00471285113051874!GO:0030133;transport vesicle;0.00481332228770941!GO:0016481;negative regulation of transcription;0.00482539871704371!GO:0031647;regulation of protein stability;0.00497269848867891!GO:0004576;oligosaccharyl transferase activity;0.00523068661740302!GO:0006596;polyamine biosynthetic process;0.00523068661740302!GO:0006541;glutamine metabolic process;0.00527318341474!GO:0009112;nucleobase metabolic process;0.00543157717984753!GO:0008415;acyltransferase activity;0.00555358685752612!GO:0006749;glutathione metabolic process;0.00559778106545912!GO:0006650;glycerophospholipid metabolic process;0.00562622326648739!GO:0006144;purine base metabolic process;0.00563683887432648!GO:0006497;protein amino acid lipidation;0.00575720660535791!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.00578947727906268!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00586240576926448!GO:0000323;lytic vacuole;0.00587968887788643!GO:0005764;lysosome;0.00587968887788643!GO:0016197;endosome transport;0.00591832093013332!GO:0006310;DNA recombination;0.00597292534955168!GO:0007040;lysosome organization and biogenesis;0.00610718880898803!GO:0008632;apoptotic program;0.00625687117311239!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00629588238555263!GO:0015002;heme-copper terminal oxidase activity;0.00629588238555263!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00629588238555263!GO:0004129;cytochrome-c oxidase activity;0.00629588238555263!GO:0031323;regulation of cellular metabolic process;0.00642773523553918!GO:0006284;base-excision repair;0.00649808436166883!GO:0016310;phosphorylation;0.00656604793505258!GO:0050789;regulation of biological process;0.00657956006236897!GO:0006275;regulation of DNA replication;0.00672541363593702!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00678238668067151!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00680270553819254!GO:0046983;protein dimerization activity;0.00682422829311941!GO:0048519;negative regulation of biological process;0.0068537865843907!GO:0042770;DNA damage response, signal transduction;0.00686758486262364!GO:0044270;nitrogen compound catabolic process;0.00710105009953262!GO:0005758;mitochondrial intermembrane space;0.00711062796184668!GO:0004532;exoribonuclease activity;0.00760320203803466!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00760320203803466!GO:0003702;RNA polymerase II transcription factor activity;0.00763017025211493!GO:0065009;regulation of a molecular function;0.00800434590943987!GO:0043022;ribosome binding;0.00815107033642241!GO:0006891;intra-Golgi vesicle-mediated transport;0.00822827006456079!GO:0051716;cellular response to stimulus;0.00840202592269259!GO:0030660;Golgi-associated vesicle membrane;0.00843114081107684!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00872394917222095!GO:0000725;recombinational repair;0.00872394917222095!GO:0000724;double-strand break repair via homologous recombination;0.00872394917222095!GO:0008250;oligosaccharyl transferase complex;0.00889915535871724!GO:0006354;RNA elongation;0.00907934227657873!GO:0005832;chaperonin-containing T-complex;0.00926487052057482!GO:0008180;signalosome;0.00977339327993235!GO:0009310;amine catabolic process;0.0101081279384687!GO:0051101;regulation of DNA binding;0.0102382185392832!GO:0007017;microtubule-based process;0.0102830242139927!GO:0006642;triacylglycerol mobilization;0.0104027319290887!GO:0043596;nuclear replication fork;0.0104810969013805!GO:0005996;monosaccharide metabolic process;0.0105072112099772!GO:0006289;nucleotide-excision repair;0.0105536213683838!GO:0051539;4 iron, 4 sulfur cluster binding;0.0105985910355189!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.0107131881326551!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0108536204812859!GO:0043624;cellular protein complex disassembly;0.0108978369167983!GO:0001889;liver development;0.0114081566275616!GO:0004300;enoyl-CoA hydratase activity;0.0116977943528494!GO:0009066;aspartate family amino acid metabolic process;0.0119301783074053!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0122108438761172!GO:0000178;exosome (RNase complex);0.0122980224356985!GO:0006790;sulfur metabolic process;0.0125775401274025!GO:0004029;aldehyde dehydrogenase (NAD) activity;0.0126188041952047!GO:0050750;low-density lipoprotein receptor binding;0.012782056059677!GO:0051287;NAD binding;0.0130221767694305!GO:0030663;COPI coated vesicle membrane;0.0131188826146899!GO:0030126;COPI vesicle coat;0.0131188826146899!GO:0031123;RNA 3'-end processing;0.0131591054426733!GO:0046489;phosphoinositide biosynthetic process;0.0132061651857938!GO:0016272;prefoldin complex;0.0132061651857938!GO:0008538;proteasome activator activity;0.0134516862243939!GO:0006378;mRNA polyadenylation;0.0134562074479527!GO:0050681;androgen receptor binding;0.0136027023650839!GO:0032200;telomere organization and biogenesis;0.0140578497254796!GO:0000723;telomere maintenance;0.0140578497254796!GO:0019318;hexose metabolic process;0.0141537586585464!GO:0043407;negative regulation of MAP kinase activity;0.0149980165882266!GO:0005525;GTP binding;0.0159077540623742!GO:0018196;peptidyl-asparagine modification;0.0159077540623742!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0159077540623742!GO:0000139;Golgi membrane;0.0160505305895137!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0166304088101564!GO:0007033;vacuole organization and biogenesis;0.0166653289247086!GO:0003924;GTPase activity;0.0166653289247086!GO:0008286;insulin receptor signaling pathway;0.0167452134744073!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0168286228150875!GO:0030518;steroid hormone receptor signaling pathway;0.0168774497076441!GO:0004177;aminopeptidase activity;0.0168879039386629!GO:0006400;tRNA modification;0.0169291340942849!GO:0033673;negative regulation of kinase activity;0.0169515366268744!GO:0006469;negative regulation of protein kinase activity;0.0169515366268744!GO:0031970;organelle envelope lumen;0.0169901840253006!GO:0006417;regulation of translation;0.017198224554894!GO:0030176;integral to endoplasmic reticulum membrane;0.017198224554894!GO:0006730;one-carbon compound metabolic process;0.0172332478327578!GO:0006506;GPI anchor biosynthetic process;0.0175518125667406!GO:0006631;fatty acid metabolic process;0.0177486556082046!GO:0040029;regulation of gene expression, epigenetic;0.0180794266133358!GO:0000152;nuclear ubiquitin ligase complex;0.0181900360924972!GO:0009074;aromatic amino acid family catabolic process;0.018276814006551!GO:0006778;porphyrin metabolic process;0.0182884836226648!GO:0033013;tetrapyrrole metabolic process;0.0182884836226648!GO:0016790;thiolester hydrolase activity;0.0184020741264058!GO:0050748;negative regulation of lipoprotein metabolic process;0.0187547817745484!GO:0005874;microtubule;0.0190587875265242!GO:0031326;regulation of cellular biosynthetic process;0.0192069729846604!GO:0031570;DNA integrity checkpoint;0.0193780830033516!GO:0000792;heterochromatin;0.0195819335005097!GO:0000339;RNA cap binding;0.0198097347478661!GO:0006740;NADPH regeneration;0.019935617335016!GO:0006098;pentose-phosphate shunt;0.019935617335016!GO:0000097;sulfur amino acid biosynthetic process;0.0203011276485964!GO:0005905;coated pit;0.0203762517778814!GO:0005663;DNA replication factor C complex;0.0203762517778814!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0203869005598224!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.020542164394231!GO:0015682;ferric iron transport;0.0207029017123976!GO:0015091;ferric iron transmembrane transporter activity;0.0207029017123976!GO:0031643;positive regulation of myelination;0.0207029017123976!GO:0051540;metal cluster binding;0.0207167255676908!GO:0051536;iron-sulfur cluster binding;0.0207167255676908!GO:0016835;carbon-oxygen lyase activity;0.0213037722376514!GO:0000209;protein polyubiquitination;0.0213037722376514!GO:0051348;negative regulation of transferase activity;0.0213934577696775!GO:0006505;GPI anchor metabolic process;0.0217077304021427!GO:0001558;regulation of cell growth;0.0217077304021427!GO:0032984;macromolecular complex disassembly;0.0218747498789582!GO:0008361;regulation of cell size;0.0218916569542469!GO:0008320;protein transmembrane transporter activity;0.0218916569542469!GO:0006376;mRNA splice site selection;0.0221238323321153!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0221238323321153!GO:0031625;ubiquitin protein ligase binding;0.0222290801129948!GO:0004003;ATP-dependent DNA helicase activity;0.0223752424774059!GO:0005669;transcription factor TFIID complex;0.0227276772633286!GO:0007021;tubulin folding;0.0230770064949289!GO:0000781;chromosome, telomeric region;0.0233340547536082!GO:0003756;protein disulfide isomerase activity;0.0233882175616102!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0233882175616102!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0237938197780534!GO:0000287;magnesium ion binding;0.024040011950648!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0249236721178844!GO:0030027;lamellipodium;0.0254281511339216!GO:0043601;nuclear replisome;0.0254337074264367!GO:0030894;replisome;0.0254337074264367!GO:0016044;membrane organization and biogenesis;0.0255997541340938!GO:0006350;transcription;0.0257147862897984!GO:0006301;postreplication repair;0.0262106152297601!GO:0006720;isoprenoid metabolic process;0.0264089357256914!GO:0006379;mRNA cleavage;0.0268644376175223!GO:0030261;chromosome condensation;0.0280398081407752!GO:0030137;COPI-coated vesicle;0.0281136754590431!GO:0006518;peptide metabolic process;0.0285391562558981!GO:0043241;protein complex disassembly;0.0288047415993248!GO:0004540;ribonuclease activity;0.0288047415993248!GO:0051098;regulation of binding;0.0288321869115332!GO:0015631;tubulin binding;0.0289127571616653!GO:0008536;Ran GTPase binding;0.0289936558231403!GO:0006081;aldehyde metabolic process;0.0290156387732628!GO:0004722;protein serine/threonine phosphatase activity;0.0290294013899619!GO:0004680;casein kinase activity;0.0297151847410484!GO:0009116;nucleoside metabolic process;0.0297151847410484!GO:0032259;methylation;0.0297657673738541!GO:0005652;nuclear lamina;0.0300948995881792!GO:0005732;small nucleolar ribonucleoprotein complex;0.0301637358269383!GO:0046982;protein heterodimerization activity;0.031220026986551!GO:0044438;microbody part;0.0314356826326403!GO:0044439;peroxisomal part;0.0314356826326403!GO:0009067;aspartate family amino acid biosynthetic process;0.0317920281907316!GO:0051053;negative regulation of DNA metabolic process;0.0320030101585043!GO:0008234;cysteine-type peptidase activity;0.0320330220801309!GO:0030384;phosphoinositide metabolic process;0.0326224847286563!GO:0001887;selenium metabolic process;0.0326224847286563!GO:0007034;vacuolar transport;0.0330683983133668!GO:0009889;regulation of biosynthetic process;0.0331245840156741!GO:0016049;cell growth;0.0333812812449939!GO:0030036;actin cytoskeleton organization and biogenesis;0.0339979718221328!GO:0031406;carboxylic acid binding;0.0341581336912255!GO:0043189;H4/H2A histone acetyltransferase complex;0.0344431098838232!GO:0000228;nuclear chromosome;0.0345272744816357!GO:0005784;translocon complex;0.0348405825808636!GO:0008299;isoprenoid biosynthetic process;0.0349117421832063!GO:0044272;sulfur compound biosynthetic process;0.0349807979247878!GO:0047115;trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;0.0350845958129298!GO:0007010;cytoskeleton organization and biogenesis;0.0351270538823595!GO:0007004;telomere maintenance via telomerase;0.0358342925102683!GO:0008216;spermidine metabolic process;0.0358631762188164!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0360679344037595!GO:0043414;biopolymer methylation;0.0365449866077984!GO:0042026;protein refolding;0.0369014063995037!GO:0008537;proteasome activator complex;0.0372875879385316!GO:0009225;nucleotide-sugar metabolic process;0.0373445333235044!GO:0019438;aromatic compound biosynthetic process;0.0378597886078646!GO:0046467;membrane lipid biosynthetic process;0.0378597886078646!GO:0004659;prenyltransferase activity;0.037914540080396!GO:0045893;positive regulation of transcription, DNA-dependent;0.0382895640313748!GO:0007346;regulation of progression through mitotic cell cycle;0.0388716093010215!GO:0019783;small conjugating protein-specific protease activity;0.0388716093010215!GO:0006635;fatty acid beta-oxidation;0.0389282607315387!GO:0017166;vinculin binding;0.039175726774956!GO:0008430;selenium binding;0.0393871164103237!GO:0000726;non-recombinational repair;0.0393871164103237!GO:0008295;spermidine biosynthetic process;0.0394438889192371!GO:0003985;acetyl-CoA C-acetyltransferase activity;0.0395483593699661!GO:0006907;pinocytosis;0.0400530655631851!GO:0031902;late endosome membrane;0.0400530655631851!GO:0004873;asialoglycoprotein receptor activity;0.0403061387166645!GO:0008143;poly(A) binding;0.0405676776336244!GO:0031577;spindle checkpoint;0.040579980783276!GO:0022411;cellular component disassembly;0.0406170097375339!GO:0022406;membrane docking;0.040628643882678!GO:0048278;vesicle docking;0.040628643882678!GO:0042168;heme metabolic process;0.0406654668526953!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.040863215719054!GO:0000175;3'-5'-exoribonuclease activity;0.0415503834802418!GO:0045045;secretory pathway;0.0416307022648425!GO:0019959;interleukin-8 binding;0.0424771229354502!GO:0010037;response to carbon dioxide;0.0424771229354502!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0431679994495774!GO:0045039;protein import into mitochondrial inner membrane;0.0431679994495774!GO:0005774;vacuolar membrane;0.0431679994495774!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0432905933338285!GO:0004843;ubiquitin-specific protease activity;0.043470071241563!GO:0031371;ubiquitin conjugating enzyme complex;0.0439013879119889!GO:0044450;microtubule organizing center part;0.0440214067451436!GO:0009309;amine biosynthetic process;0.0440749999886112!GO:0006564;L-serine biosynthetic process;0.044570562947503!GO:0016836;hydro-lyase activity;0.04564118465359!GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;0.0463302082464789!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0465285692433799!GO:0000123;histone acetyltransferase complex;0.0465389483520644!GO:0007041;lysosomal transport;0.0470317180249386!GO:0019321;pentose metabolic process;0.047084807695552!GO:0008408;3'-5' exonuclease activity;0.0473556296039642!GO:0031903;microbody membrane;0.0474040899632427!GO:0005778;peroxisomal membrane;0.0474040899632427!GO:0019511;peptidyl-proline hydroxylation;0.0474040899632427!GO:0018208;peptidyl-proline modification;0.0474040899632427!GO:0019471;4-hydroxyproline metabolic process;0.0474040899632427!GO:0018401;peptidyl-proline hydroxylation to 4-hydroxy-L-proline;0.0474040899632427!GO:0043065;positive regulation of apoptosis;0.0475737445732234!GO:0004185;serine carboxypeptidase activity;0.0476514156500074!GO:0030508;thiol-disulfide exchange intermediate activity;0.0476514156500074!GO:0006879;cellular iron ion homeostasis;0.0476514156500074!GO:0055072;iron ion homeostasis;0.0476514156500074!GO:0002018;renin-angiotensin regulation of aldosterone production;0.0476514156500074!GO:0048143;astrocyte activation;0.0476514156500074!GO:0046622;positive regulation of organ growth;0.0476514156500074!GO:0031701;angiotensin receptor binding;0.0476514156500074!GO:0031703;type 2 angiotensin receptor binding;0.0476514156500074!GO:0045723;positive regulation of fatty acid biosynthetic process;0.0476514156500074!GO:0001999;renal response to blood flow during renin-angiotensin regulation of systemic arterial blood pressure;0.0476514156500074!GO:0042756;drinking behavior;0.0476514156500074!GO:0002019;angiotensin mediated regulation of renal output;0.0476514156500074!GO:0031702;type 1 angiotensin receptor binding;0.0476514156500074!GO:0001998;angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure;0.0476514156500074!GO:0009124;nucleoside monophosphate biosynthetic process;0.0477183107711627!GO:0009123;nucleoside monophosphate metabolic process;0.0477183107711627!GO:0010468;regulation of gene expression;0.0477183107711627!GO:0030118;clathrin coat;0.0477415078639011!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0480035552750248!GO:0003725;double-stranded RNA binding;0.0480273112270006!GO:0035267;NuA4 histone acetyltransferase complex;0.0484394096381427!GO:0008017;microtubule binding;0.0485856045404713!GO:0001725;stress fiber;0.0491957688500635!GO:0032432;actin filament bundle;0.0491957688500635!GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors;0.0493708433308699!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0496951370735769!GO:0008097;5S rRNA binding;0.0497336623842935!GO:0016584;nucleosome positioning;0.0498625789274497 | |||
|sample_id=10820 | |sample_id=10820 | ||
|sample_note= | |sample_note= | ||
|sample_sex=male | |sample_sex=male | ||
|sample_species= | |sample_species=Human (Homo sapiens) | ||
|sample_strain= | |sample_strain= | ||
|sample_tissue=liver | |sample_tissue=liver | ||
|top_motifs=HNF4A_NR2F1,2:4.79489922739;HNF1A:4.15674580962;RXR{A,B,G}_{NR1H2,PPAR}dimers:3.70886331688;FOXA2:3.28094513886;LEF1_TCF7_TCF7L1,2:2.19703770575;bHLH_family:2.14861616564;FOX{F1,F2,J1}:1.86324120674;NFY{A,B,C}:1.66870148087;NR6A1:1.53232542716;ONECUT1,2:1.47765464728;E2F1..5:1.47592317324;ELK1,4_GABP{A,B1}:1.23872793575;NR1H4:1.23461280756;ADNP_IRX_SIX_ZHX:1.22934199989;ZNF143:1.22412043089;YY1:1.20862518294;EN1,2:1.06665004701;SOX{8,9,10}:1.06174733679;PBX1:1.04782136736;AIRE:0.98829447571;GFI1:0.98484139588;NRF1:0.920649391277;NR5A1,2:0.874768753787;SNAI1..3:0.856303376606;PAX3,7:0.837744510058;RORA:0.79861321017;NKX3-2:0.771750133057;TOPORS:0.759765491852;MYB:0.697958246999;SOX2:0.683448595365;LHX3,4:0.662898727197;ZEB1:0.65942116707;CEBPA,B_DDIT3:0.613502778284;RXRA_VDR{dimer}:0.586732412275;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.575912015516;FOXM1:0.567846136374;ALX4:0.497064052524;ESRRA:0.47231716769;FOX{D1,D2}:0.450645710745;PITX1..3:0.425379426971;TP53:0.423384381828;TFDP1:0.410184480164;EBF1:0.344287564557;MYOD1:0.329055318413;HIC1:0.324836155651;AR:0.320502696575;XCPE1{core}:0.300921503577;FOXD3:0.299343646739;HLF:0.253034137309;NFIL3:0.247875662216;POU6F1:0.19377342825;PPARG:0.181084785694;ELF1,2,4:0.157234911242;CUX2:0.151659047194;FOXP1:0.150339252802;STAT5{A,B}:0.118364349087;DBP:0.111274202656;PAX4:0.102549210155;MTE{core}:0.0843819045578;GATA6:0.0704830260118;SP1:0.0676730424047;MAZ:0.0574476049822;ZFP161:0.0432753769729;BREu{core}:0.034747475777;NKX3-1:0.0288551279048;UFEwm:-0.00115933343807;SOX5:-0.00375613758848;RBPJ:-0.0136885623597;TFCP2:-0.028940951366;TFAP2{A,C}:-0.0526428295901;ARID5B:-0.059325773711;SREBF1,2:-0.0727296082073;PAX2:-0.0964500460761;FOXQ1:-0.0971982231484;SOX17:-0.0997918067386;EVI1:-0.135058742636;T:-0.136089760285;CDC5L:-0.141628942961;PAX1,9:-0.1440933795;VSX1,2:-0.14497351687;TBX4,5:-0.152203793972;RXR{A,B,G}:-0.156010726229;NFKB1_REL_RELA:-0.16415423961;KLF4:-0.165227177282;STAT2,4,6:-0.165517342186;HOXA9_MEIS1:-0.189971082165;MED-1{core}:-0.205918083093;AHR_ARNT_ARNT2:-0.214634109497;LMO2:-0.233844518225;GLI1..3:-0.235065286609;PATZ1:-0.237935863777;TEAD1:-0.259816226482;POU3F1..4:-0.261919752527;ATF5_CREB3:-0.292632998736;MTF1:-0.303324225714;HOX{A5,B5}:-0.343292041025;STAT1,3:-0.346937591822;TLX1..3_NFIC{dimer}:-0.361979596959;TAL1_TCF{3,4,12}:-0.378302518924;ATF6:-0.385324785709;FOXN1:-0.389810556209;FOSL2:-0.404244924148;BPTF:-0.41064733055;ZNF148:-0.418390428381;NFE2:-0.421036518576;ESR1:-0.444171029788;CREB1:-0.447163137058;ZNF423:-0.449556038679;IRF7:-0.455765145368;DMAP1_NCOR{1,2}_SMARC:-0.45683060099;HOX{A4,D4}:-0.459790075376;HOX{A6,A7,B6,B7}:-0.467895264854;FOXO1,3,4:-0.470025126306;IKZF2:-0.474506016029;HES1:-0.50934388326;OCT4_SOX2{dimer}:-0.509672867534;POU2F1..3:-0.51370714317;REST:-0.521637185438;NKX6-1,2:-0.539231323858;NKX2-3_NKX2-5:-0.54144901116;IRF1,2:-0.550938756496;GTF2A1,2:-0.554792862096;FOS_FOS{B,L1}_JUN{B,D}:-0.559606984292;GATA4:-0.571006511047;NFE2L2:-0.572143578382;NANOG{mouse}:-0.584195857887;BACH2:-0.596434522525;POU5F1:-0.598747557707;PAX5:-0.598789630056;NR3C1:-0.614164326561;RFX2..5_RFXANK_RFXAP:-0.625690901673;CDX1,2,4:-0.630608083756;ATF4:-0.637273290144;FOXP3:-0.638749043053;EGR1..3:-0.641133517395;ZBTB16:-0.644252011753;TBP:-0.6488505454;IKZF1:-0.654981581328;PDX1:-0.656384877817;SPI1:-0.659815756185;ATF2:-0.660971287191;SPIB:-0.66265416194;PAX8:-0.663390241483;XBP1:-0.663461946158;RREB1:-0.672884714426;ALX1:-0.676959472369;NFIX:-0.706670308976;TFAP2B:-0.738307727604;MYBL2:-0.740243696716;SRF:-0.787934317686;NHLH1,2:-0.78864316682;HSF1,2:-0.793263623152;MEF2{A,B,C,D}:-0.803685989872;RFX1:-0.842381476787;NKX2-2,8:-0.847533213266;GTF2I:-0.851049930485;JUN:-0.851634836205;HMGA1,2:-0.85549949622;HAND1,2:-0.857144696788;MYFfamily:-0.876758402729;RUNX1..3:-0.888916293547;GCM1,2:-0.891126046233;ZBTB6:-0.943957369801;CRX:-1.00956012356;ETS1,2:-1.04814527658;ZIC1..3:-1.0537545522;POU1F1:-1.0574304188;TFAP4:-1.05945828406;MAFB:-1.05979860937;NKX2-1,4:-1.06799278697;GFI1B:-1.07202974465;PRDM1:-1.0785146347;NFE2L1:-1.08347923675;ZNF384:-1.09271843507;FOX{I1,J2}:-1.1022475061;PAX6:-1.14364054218;SPZ1:-1.1457298066;EP300:-1.1475564127;MZF1:-1.21280396701;PRRX1,2:-1.26983335219;NFATC1..3:-1.28640399381;NANOG:-1.32158074644;TGIF1:-1.41415422759;ZNF238:-1.44425329126;TEF:-1.53566371064;HBP1_HMGB_SSRP1_UBTF:-1.60651166154;GZF1:-1.66471205192;TLX2:-1.74346414584;SMAD1..7,9:-1.77536123114;HIF1A:-1.79732203238;FOXL1:-1.93984636463;HMX1:-1.94158043128 | |top_motifs=HNF4A_NR2F1,2:4.79489922739;HNF1A:4.15674580962;RXR{A,B,G}_{NR1H2,PPAR}dimers:3.70886331688;FOXA2:3.28094513886;LEF1_TCF7_TCF7L1,2:2.19703770575;bHLH_family:2.14861616564;FOX{F1,F2,J1}:1.86324120674;NFY{A,B,C}:1.66870148087;NR6A1:1.53232542716;ONECUT1,2:1.47765464728;E2F1..5:1.47592317324;ELK1,4_GABP{A,B1}:1.23872793575;NR1H4:1.23461280756;ADNP_IRX_SIX_ZHX:1.22934199989;ZNF143:1.22412043089;YY1:1.20862518294;EN1,2:1.06665004701;SOX{8,9,10}:1.06174733679;PBX1:1.04782136736;AIRE:0.98829447571;GFI1:0.98484139588;NRF1:0.920649391277;NR5A1,2:0.874768753787;SNAI1..3:0.856303376606;PAX3,7:0.837744510058;RORA:0.79861321017;NKX3-2:0.771750133057;TOPORS:0.759765491852;MYB:0.697958246999;SOX2:0.683448595365;LHX3,4:0.662898727197;ZEB1:0.65942116707;CEBPA,B_DDIT3:0.613502778284;RXRA_VDR{dimer}:0.586732412275;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.575912015516;FOXM1:0.567846136374;ALX4:0.497064052524;ESRRA:0.47231716769;FOX{D1,D2}:0.450645710745;PITX1..3:0.425379426971;TP53:0.423384381828;TFDP1:0.410184480164;EBF1:0.344287564557;MYOD1:0.329055318413;HIC1:0.324836155651;AR:0.320502696575;XCPE1{core}:0.300921503577;FOXD3:0.299343646739;HLF:0.253034137309;NFIL3:0.247875662216;POU6F1:0.19377342825;PPARG:0.181084785694;ELF1,2,4:0.157234911242;CUX2:0.151659047194;FOXP1:0.150339252802;STAT5{A,B}:0.118364349087;DBP:0.111274202656;PAX4:0.102549210155;MTE{core}:0.0843819045578;GATA6:0.0704830260118;SP1:0.0676730424047;MAZ:0.0574476049822;ZFP161:0.0432753769729;BREu{core}:0.034747475777;NKX3-1:0.0288551279048;UFEwm:-0.00115933343807;SOX5:-0.00375613758848;RBPJ:-0.0136885623597;TFCP2:-0.028940951366;TFAP2{A,C}:-0.0526428295901;ARID5B:-0.059325773711;SREBF1,2:-0.0727296082073;PAX2:-0.0964500460761;FOXQ1:-0.0971982231484;SOX17:-0.0997918067386;EVI1:-0.135058742636;T:-0.136089760285;CDC5L:-0.141628942961;PAX1,9:-0.1440933795;VSX1,2:-0.14497351687;TBX4,5:-0.152203793972;RXR{A,B,G}:-0.156010726229;NFKB1_REL_RELA:-0.16415423961;KLF4:-0.165227177282;STAT2,4,6:-0.165517342186;HOXA9_MEIS1:-0.189971082165;MED-1{core}:-0.205918083093;AHR_ARNT_ARNT2:-0.214634109497;LMO2:-0.233844518225;GLI1..3:-0.235065286609;PATZ1:-0.237935863777;TEAD1:-0.259816226482;POU3F1..4:-0.261919752527;ATF5_CREB3:-0.292632998736;MTF1:-0.303324225714;HOX{A5,B5}:-0.343292041025;STAT1,3:-0.346937591822;TLX1..3_NFIC{dimer}:-0.361979596959;TAL1_TCF{3,4,12}:-0.378302518924;ATF6:-0.385324785709;FOXN1:-0.389810556209;FOSL2:-0.404244924148;BPTF:-0.41064733055;ZNF148:-0.418390428381;NFE2:-0.421036518576;ESR1:-0.444171029788;CREB1:-0.447163137058;ZNF423:-0.449556038679;IRF7:-0.455765145368;DMAP1_NCOR{1,2}_SMARC:-0.45683060099;HOX{A4,D4}:-0.459790075376;HOX{A6,A7,B6,B7}:-0.467895264854;FOXO1,3,4:-0.470025126306;IKZF2:-0.474506016029;HES1:-0.50934388326;OCT4_SOX2{dimer}:-0.509672867534;POU2F1..3:-0.51370714317;REST:-0.521637185438;NKX6-1,2:-0.539231323858;NKX2-3_NKX2-5:-0.54144901116;IRF1,2:-0.550938756496;GTF2A1,2:-0.554792862096;FOS_FOS{B,L1}_JUN{B,D}:-0.559606984292;GATA4:-0.571006511047;NFE2L2:-0.572143578382;NANOG{mouse}:-0.584195857887;BACH2:-0.596434522525;POU5F1:-0.598747557707;PAX5:-0.598789630056;NR3C1:-0.614164326561;RFX2..5_RFXANK_RFXAP:-0.625690901673;CDX1,2,4:-0.630608083756;ATF4:-0.637273290144;FOXP3:-0.638749043053;EGR1..3:-0.641133517395;ZBTB16:-0.644252011753;TBP:-0.6488505454;IKZF1:-0.654981581328;PDX1:-0.656384877817;SPI1:-0.659815756185;ATF2:-0.660971287191;SPIB:-0.66265416194;PAX8:-0.663390241483;XBP1:-0.663461946158;RREB1:-0.672884714426;ALX1:-0.676959472369;NFIX:-0.706670308976;TFAP2B:-0.738307727604;MYBL2:-0.740243696716;SRF:-0.787934317686;NHLH1,2:-0.78864316682;HSF1,2:-0.793263623152;MEF2{A,B,C,D}:-0.803685989872;RFX1:-0.842381476787;NKX2-2,8:-0.847533213266;GTF2I:-0.851049930485;JUN:-0.851634836205;HMGA1,2:-0.85549949622;HAND1,2:-0.857144696788;MYFfamily:-0.876758402729;RUNX1..3:-0.888916293547;GCM1,2:-0.891126046233;ZBTB6:-0.943957369801;CRX:-1.00956012356;ETS1,2:-1.04814527658;ZIC1..3:-1.0537545522;POU1F1:-1.0574304188;TFAP4:-1.05945828406;MAFB:-1.05979860937;NKX2-1,4:-1.06799278697;GFI1B:-1.07202974465;PRDM1:-1.0785146347;NFE2L1:-1.08347923675;ZNF384:-1.09271843507;FOX{I1,J2}:-1.1022475061;PAX6:-1.14364054218;SPZ1:-1.1457298066;EP300:-1.1475564127;MZF1:-1.21280396701;PRRX1,2:-1.26983335219;NFATC1..3:-1.28640399381;NANOG:-1.32158074644;TGIF1:-1.41415422759;ZNF238:-1.44425329126;TEF:-1.53566371064;HBP1_HMGB_SSRP1_UBTF:-1.60651166154;GZF1:-1.66471205192;TLX2:-1.74346414584;SMAD1..7,9:-1.77536123114;HIF1A:-1.79732203238;FOXL1:-1.93984636463;HMX1:-1.94158043128 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10820-111C1;search_select_hide=table117:FF:10820-111C1 | |||
}} | }} | ||
Latest revision as of 15:07, 3 June 2020
| Name: | hepatocellular carcinoma cell line: HepG2 ENCODE, biol_rep3 |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs12330 |
| Sample type: | cell lines |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
| Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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| CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| Download raw sequence, BAM & CTSS | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12330
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12330
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.392 |
| 10 | 10 | 0.605 |
| 100 | 100 | 0.0273 |
| 101 | 101 | 0.554 |
| 102 | 102 | 0.121 |
| 103 | 103 | 0.762 |
| 104 | 104 | 0.648 |
| 105 | 105 | 0.911 |
| 106 | 106 | 0.0115 |
| 107 | 107 | 0.527 |
| 108 | 108 | 0.494 |
| 109 | 109 | 0.0871 |
| 11 | 11 | 0.712 |
| 110 | 110 | 0.884 |
| 111 | 111 | 0.795 |
| 112 | 112 | 0.185 |
| 113 | 113 | 0.0641 |
| 114 | 114 | 0.435 |
| 115 | 115 | 0.664 |
| 116 | 116 | 0.889 |
| 117 | 117 | 0.119 |
| 118 | 118 | 0.262 |
| 119 | 119 | 0.837 |
| 12 | 12 | 0.55 |
| 120 | 120 | 0.477 |
| 121 | 121 | 0.616 |
| 122 | 122 | 0.948 |
| 123 | 123 | 0.64 |
| 124 | 124 | 0.225 |
| 125 | 125 | 0.486 |
| 126 | 126 | 0.491 |
| 127 | 127 | 0.389 |
| 128 | 128 | 0.0253 |
| 129 | 129 | 0.952 |
| 13 | 13 | 7.21401e-5 |
| 130 | 130 | 0.802 |
| 131 | 131 | 0.0336 |
| 132 | 132 | 0.545 |
| 133 | 133 | 0.0116 |
| 134 | 134 | 0.438 |
| 135 | 135 | 0.0649 |
| 136 | 136 | 0.0153 |
| 137 | 137 | 0.00473 |
| 138 | 138 | 0.426 |
| 139 | 139 | 0.237 |
| 14 | 14 | 0.0665 |
| 140 | 140 | 0.607 |
| 141 | 141 | 0.223 |
| 142 | 142 | 0.729 |
| 143 | 143 | 0.153 |
| 144 | 144 | 0.472 |
| 145 | 145 | 0.897 |
| 146 | 146 | 0.926 |
| 147 | 147 | 0.523 |
| 148 | 148 | 0.759 |
| 149 | 149 | 0.645 |
| 15 | 15 | 0.977 |
| 150 | 150 | 0.502 |
| 151 | 151 | 0.706 |
| 152 | 152 | 0.914 |
| 153 | 153 | 0.425 |
| 154 | 154 | 0.152 |
| 155 | 155 | 0.298 |
| 156 | 156 | 0.926 |
| 157 | 157 | 0.698 |
| 158 | 158 | 0.949 |
| 159 | 159 | 0.6 |
| 16 | 16 | 0.693 |
| 160 | 160 | 0.771 |
| 161 | 161 | 0.878 |
| 162 | 162 | 0.92 |
| 163 | 163 | 0.656 |
| 164 | 164 | 0.85 |
| 165 | 165 | 0.679 |
| 166 | 166 | 0.338 |
| 167 | 167 | 0.781 |
| 168 | 168 | 0.234 |
| 169 | 169 | 0.3 |
| 17 | 17 | 0.727 |
| 18 | 18 | 0.0521 |
| 19 | 19 | 0.839 |
| 2 | 2 | 0.1 |
| 20 | 20 | 0.21 |
| 21 | 21 | 0.455 |
| 22 | 22 | 0.521 |
| 23 | 23 | 0.00286 |
| 24 | 24 | 0.999 |
| 25 | 25 | 0.625 |
| 26 | 26 | 0.0751 |
| 27 | 27 | 0.235 |
| 28 | 28 | 0.871 |
| 29 | 29 | 0.203 |
| 3 | 3 | 0.877 |
| 30 | 30 | 0.736 |
| 31 | 31 | 0.817 |
| 32 | 32 | 0.17 |
| 33 | 33 | 0.321 |
| 34 | 34 | 0.487 |
| 35 | 35 | 0.981 |
| 36 | 36 | 0.137 |
| 37 | 37 | 0.714 |
| 38 | 38 | 0.733 |
| 39 | 39 | 0.873 |
| 4 | 4 | 0.876 |
| 40 | 40 | 0.00794 |
| 41 | 41 | 0.0544 |
| 42 | 42 | 0.294 |
| 43 | 43 | 0.907 |
| 44 | 44 | 0.222 |
| 45 | 45 | 0.996 |
| 46 | 46 | 0.628 |
| 47 | 47 | 0.289 |
| 48 | 48 | 0.515 |
| 49 | 49 | 0.867 |
| 5 | 5 | 0.346 |
| 50 | 50 | 0.178 |
| 51 | 51 | 0.712 |
| 52 | 52 | 0.403 |
| 53 | 53 | 0.498 |
| 54 | 54 | 0.838 |
| 55 | 55 | 0.331 |
| 56 | 56 | 0.8 |
| 57 | 57 | 0.941 |
| 58 | 58 | 0.705 |
| 59 | 59 | 0.536 |
| 6 | 6 | 0.352 |
| 60 | 60 | 0.258 |
| 61 | 61 | 0.117 |
| 62 | 62 | 0.233 |
| 63 | 63 | 0.919 |
| 64 | 64 | 0.856 |
| 65 | 65 | 0.0553 |
| 66 | 66 | 0.00842 |
| 67 | 67 | 0.318 |
| 68 | 68 | 0.148 |
| 69 | 69 | 0.459 |
| 7 | 7 | 0.0306 |
| 70 | 70 | 0.13 |
| 71 | 71 | 0.462 |
| 72 | 72 | 0.0864 |
| 73 | 73 | 0.153 |
| 74 | 74 | 0.0631 |
| 75 | 75 | 8.31018e-4 |
| 76 | 76 | 0.657 |
| 77 | 77 | 0.978 |
| 78 | 78 | 0.015 |
| 79 | 79 | 0.0183 |
| 8 | 8 | 0.918 |
| 80 | 80 | 0.033 |
| 81 | 81 | 0.137 |
| 82 | 82 | 0.078 |
| 83 | 83 | 0.0907 |
| 84 | 84 | 0.11 |
| 85 | 85 | 0.0463 |
| 86 | 86 | 0.894 |
| 87 | 87 | 0.0725 |
| 88 | 88 | 0.482 |
| 89 | 89 | 0.57 |
| 9 | 9 | 0.0589 |
| 90 | 90 | 0.451 |
| 91 | 91 | 0.0114 |
| 92 | 92 | 0.0712 |
| 93 | 93 | 0.986 |
| 94 | 94 | 0.0673 |
| 95 | 95 | 0.0029 |
| 96 | 96 | 0.295 |
| 97 | 97 | 0.625 |
| 98 | 98 | 0.689 |
| 99 | 99 | 0.202 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12330
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0100599 Hep-G2 cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0002371 (somatic cell)
0000181 (metabolising cell)
0000417 (endopolyploid cell)
0000668 (parenchymal cell)
0000412 (polyploid cell)
0000255 (eukaryotic cell)
0000182 (hepatocyte)
DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
7 (disease of anatomical entity)
305 (carcinoma)
UBERON: Anatomy
0000468 (multi-cellular organism)
0002107 (liver)
0002100 (trunk)
0001007 (digestive system)
0004119 (endoderm-derived structure)
0000062 (organ)
0000475 (organism subdivision)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0009569 (subdivision of trunk)
0002368 (endocrine gland)
0005177 (trunk region element)
0002365 (exocrine gland)
0005172 (abdomen element)
0006925 (digestive gland)
0002530 (gland)
0010317 (germ layer / neural crest derived structure)
0005173 (abdominal segment element)
0002417 (abdominal segment of trunk)
0000949 (endocrine system)
0002330 (exocrine system)
0000916 (abdomen)
0002423 (hepatobiliary system)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100297 (carcinoma cell line sample)
0101120 (epithelial cell line sample)
0100224 (liver cell line sample)
0100578 (hepatoma cell line sample)
0100599 (Hep-G2 cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000223 (endodermal cell)
UBERON:0001041 (foregut)
UBERON:0002532 (epiblast (generic))
UBERON:0006595 (presumptive endoderm)
UBERON:0003104 (mesenchyme)
UBERON:0004161 (septum transversum)
UBERON:0009497 (epithelium of foregut-midgut junction)
UBERON:0010316 (germ layer / neural crest)
