FF:13163-141B4: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005157 | ||
| | |DRA_sample_Accession_RNASeq=sRNA-Seq@SAMD00005157 | ||
| | |accession_numbers=CAGE;DRX008593;DRR009465;DRZ000890;DRZ002275;DRZ012240;DRZ013625 | ||
| | |accession_numbers_RNASeq=sRNA-Seq;DRX037288;DRR041654;DRZ007296 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0000310,UBERON:0002100,UBERON:0000475,UBERON:0000061,UBERON:0000465,UBERON:0001062,UBERON:0009569,UBERON:0001443,UBERON:0000915 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0000255 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:14566,DOID:0050687,DOID:7,DOID:5093,DOID:305,DOID:299,DOID:1612 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0000350,FF:0000344,FF:0000330,FF:0100093,FF:0100297,FF:0101912,FF:0101120,FF:0100816,FF:0100167,FF:0100356,FF:0000426 | |||
|comment= | |||
|created_by= | |||
|creation_date= | |||
| | |data_phase=2 | ||
| | |datafreeze_phase=2 | ||
| | |def= | ||
| | |donor=biol_rep3 | ||
|expression_enrichment_score=chr10:8096631..8096660,+!p1@GATA3!2.81!763.19!GATA3;;chr14:38064429..38064486,-!p1@FOXA1!2.59!383.74!FOXA1;;chr6:34524093..34524135,-!p1@SPDEF!2.39!245.53!SPDEF;;chr20:55204351..55204377,+!p1@TFAP2C!2.13!167.40!TFAP2C;;chr1:201979743..201979762,+!p1@ELF3!1.96!90.14!ELF3;;chr10:8096772..8096787,+!p2@GATA3!1.91!93.57!GATA3;;chr17:59477233..59477263,+!p1@TBX2!1.73!157.96!TBX2;;chr22:29196433..29196445,-!p4@XBP1!1.66!48.93!XBP1;;chr8:102504651..102504683,+!p1@GRHL2!1.63!42.07!GRHL2;;chr17:59477197..59477212,+!p2@TBX2!1.56!59.24!TBX2;;chr5:2751762..2751784,-!p1@IRX2!1.53!32.62!IRX2;;chr10:8095593..8095625,+!p3@GATA3!1.50!36.06!GATA3;;chr6:152128810..152128827,+!p2@ESR1!1.50!30.91!ESR1;;chr22:29196492..29196503,-!p3@XBP1!1.49!45.50!XBP1;;chr10:8097321..8097348,+!p4@GATA3!1.44!26.61!GATA3;;chr10:8100691..8100732,+!p5@GATA3!1.43!25.75!GATA3;;chr14:37131058..37131139,+!p1@PAX9!1.43!25.75!PAX9;;chr3:147111198..147111225,+!p4@ZIC1!1.43!25.75!ZIC1;;chr6:126070769..126070801,+!p1@HEY2!1.42!29.19!HEY2;;chr15:96869511..96869525,+!p16@NR2F2!1.40!26.61!NR2F2;;chr8:99956662..99956684,+!p1@OSR2!1.39!36.06!OSR2;;chr8:102504979..102505010,+!p2@GRHL2!1.37!22.32!GRHL2;;chr9:129376233..129376251,+!p2@LMX1B!1.37!22.32!LMX1B;;chr22:29196547..29196563,-!p2@XBP1!1.34!740.87!XBP1;;chr20:50159198..50159299,-!p1@NFATC2!1.30!27.47!NFATC2;;chr12:53625966..53626012,-!p2@RARG!1.27!46.36!RARG;;chr11:65554528..65554546,+!p1@OVOL1!1.26!17.17!OVOL1;;chr3:147111231..147111281,+!p3@ZIC1!1.26!17.17!ZIC1;;chr17:59477403..59477414,+!p4@TBX2!1.26!17.17!TBX2;;chr5:174151553..174151610,+!p1@MSX2!1.25!27.47!MSX2;;chr19:45579725..45579743,-!p1@ZNF296!1.24!72.97!ZNF296;;chr14:75988771..75988826,+!p1@BATF!1.23!21.46!BATF;;chr6:135502501..135502546,+!p1@MYB!1.22!18.89!MYB;;chr14:38064307..38064323,-!p3@FOXA1!1.22!15.45!FOXA1;;chr14:38064590..38064606,-!p2@FOXA1!1.22!15.45!FOXA1;;chr20:46130619..46130664,+!p1@NCOA3!1.20!397.48!NCOA3;;chr9:129376201..129376225,+!p1@LMX1B!1.19!14.59!LMX1B;;chr16:29818199..29818216,+!p11@MAZ!1.18!23.18!MAZ;;chr8:102504690..102504704,+!p3@GRHL2!1.17!13.74!GRHL2;;chr10:8097295..8097320,+!p6@GATA3!1.17!13.74!GATA3;;chr14:38064495..38064506,-!p4@FOXA1!1.17!13.74!FOXA1;;chr11:65554563..65554576,+!p2@OVOL1!1.14!12.88!OVOL1;;chr5:2751785..2751808,-!p2@IRX2!1.14!12.88!IRX2;;chr20:42295745..42295765,+!p1@MYBL2!1.13!202.60!MYBL2;;chr6:10415276..10415341,-!p2@TFAP2A!1.13!15.45!TFAP2A;;chr12:54332608..54332636,+!p1@HOXC13!1.11!12.02!HOXC13;;chr16:54964740..54964789,+!p1@IRX5!1.09!16.31!IRX5;;chr1:201979703..201979721,+!p2@ELF3!1.08!11.16!ELF3;;chr20:52210553..52210568,-!p7@ZNF217!1.08!11.16!ZNF217;;chr1:935398..935465,-!p2@HES4!1.05!21.46!HES4;;chr14:105267423..105267443,+!p2@ZBTB42!1.05!10.30!ZBTB42;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.05!10.30!ZBED1;;chr14:95236551..95236576,-!p2@GSC!1.05!10.30!GSC;;chr8:22550982..22550999,-!p1@EGR3!1.04!28.33!EGR3;;chr17:59477275..59477286,+!p3@TBX2!1.03!12.88!TBX2;;chr16:29818160..29818188,+!p6@MAZ!1.02!44.64!MAZ;;chr5:174151612..174151633,+!p2@MSX2!1.02!9.44!MSX2;;chr6:152128782..152128803,+!p5@ESR1!1.02!9.44!ESR1;;chr10:48355030..48355090,+!p1@ZNF488!1.01!12.02!ZNF488;;chr1:149858461..149858479,+!p1@BOLA1!0.98!3417.63!BOLA1;;chr17:61920023..61920110,-!p1@SMARCD2!0.98!121.91!SMARCD2;;chr3:128206762..128206781,-!p2@GATA2!0.98!54.08!GATA2;;chr15:67418177..67418204,+!p9@SMAD3!0.98!8.58!SMAD3;;chr10:135122906..135122921,+!p4@ZNF511!0.98!8.58!ZNF511;;chr14:38065203..38065215,-!p9@FOXA1!0.98!8.58!FOXA1;;chr7:156803329..156803362,-!p1@MNX1!0.98!8.58!MNX1;;chr1:23857698..23857733,-!p1@E2F2!0.97!15.45!E2F2;;chr1:209979467..209979494,-!p1@IRF6!0.97!9.44!IRF6;;chr5:176738887..176738934,-!p1@MXD3!0.96!55.80!MXD3;;chr19:48774586..48774670,+!p1@ZNF114!0.96!10.30!ZNF114;;chr8:116681409..116681431,-!p2@TRPS1!0.95!22.32!TRPS1;;chr8:37553292..37553317,+!p1@ZNF703!0.94!188.87!ZNF703;;chr17:17726907..17726958,-!p2@SREBF1!0.94!49.79!SREBF1;;chr15:67418119..67418162,+!p5@SMAD3!0.94!8.58!SMAD3;;chr20:18038521..18038571,-!p1@OVOL2!0.94!7.73!OVOL2;;chr17:61919985..61920012,-!p3@SMARCD2!0.93!18.89!SMARCD2;;chr8:125985531..125985571,+!p1@ZNF572!0.93!15.45!ZNF572;;chr2:157199008..157199023,-!p3@NR4A2!0.91!15.45!NR4A2;;chr2:71127699..71127744,+!p1@VAX2!0.90!14.59!VAX2;;chr6:10413188..10413249,-!p7@TFAP2A!0.90!6.87!TFAP2A;;chr6:152011654..152011682,+!p1@ESR1!0.90!6.87!ESR1;;chr6:152126830..152126847,+!p4@ESR1!0.90!6.87!ESR1;;chr14:95236440..95236465,-!p1@GSC!0.90!6.87!GSC;;chr19:33793430..33793447,-!p1@CEBPA!0.89!30.05!CEBPA;;chr20:46130602..46130613,+!p3@NCOA3!0.89!20.60!NCOA3;;chr15:67418047..67418093,+!p4@SMAD3!0.89!8.58!SMAD3;;chr6:10412392..10412409,-!p4@TFAP2A!0.89!7.73!TFAP2A;;chr9:110252035..110252057,-!p1@KLF4!0.88!110.74!KLF4;;chr7:149470641..149470694,-!p1@ZNF467!0.86!30.05!ZNF467;;chr11:47236584..47236679,+!p1@DDB2!0.85!70.40!DDB2;;chr6:34524049..34524089,-!p2@SPDEF!0.85!6.01!SPDEF;;chr7:155250249..155250278,+!p@chr7:155250249..155250278,+!0.85!6.01!EN2;;chr17:80797886..80797906,-!p1@ZNF750!0.85!6.01!ZNF750;;chr20:46130672..46130686,+!p2@NCOA3!0.83!27.47!NCOA3;;chr14:69262789..69262822,-!p2@ZFP36L1!0.82!15.45!ZFP36L1;;chr19:44764031..44764072,+!p1@ZNF233!0.81!6.87!ZNF233;;chr19:49140609..49140643,-!p1@DBP!0.80!32.62!DBP;;chr12:80084737..80084763,-!p3@PAWR!0.80!21.46!PAWR;;chr1:149871171..149871192,+!p4@BOLA1!0.80!12.88!BOLA1;;chr16:29818132..29818144,+!p12@MAZ!0.80!11.16!MAZ;;chr17:61919812..61919833,-!p6@SMARCD2!0.80!6.87!SMARCD2;;chr20:39317868..39317884,-!p1@MAFB!0.79!66.96!MAFB;;chr20:55205791..55205817,+!p3@TFAP2C!0.79!5.15!TFAP2C;;chr10:135122868..135122893,+!p3@ZNF511!0.79!5.15!ZNF511;;chr14:38064536..38064550,-!p7@FOXA1!0.79!5.15!FOXA1;;chr3:181429741..181429767,+!p2@SOX2!0.79!5.15!SOX2;;chr6:135502472..135502489,+!p3@MYB!0.79!5.15!MYB;;chr6:152011695..152011709,+!p6@ESR1!0.79!5.15!ESR1;;chr6:34524025..34524045,-!p3@SPDEF!0.79!5.15!SPDEF;;chr3:150126101..150126118,+!p6@TSC22D2!0.78!8.58!TSC22D2;;chr19:17356189..17356221,-!p2@NR2F6!0.78!8.58!NR2F6;;chr1:154975258..154975330,+!p1@ZBTB7B!0.77!19.75!ZBTB7B;;chr17:7388010..7388017,-!p5@ZBTB4!0.77!8.58!ZBTB4;;chr6:10412600..10412637,-!p1@TFAP2A!0.77!8.58!TFAP2A;;chr1:41827095..41827155,+!p1@FOXO6!0.77!6.87!FOXO6;;chr11:120107344..120107351,+!p1@POU2F3!0.77!6.01!POU2F3;;chr2:172967621..172967637,-!p1@DLX2!0.76!13.74!DLX2;;chr17:38465413..38465438,+!p5@RARA!0.75!7.73!RARA;;chr8:81397820..81397836,+!p2@ZBTB10!0.75!6.01!ZBTB10;;chr8:81397846..81397860,+!p3@ZBTB10!0.75!6.01!ZBTB10;;chr8:37553261..37553282,+!p2@ZNF703!0.74!37.77!ZNF703;;chr2:239148671..239148686,-!p1@HES6!0.74!18.03!HES6;;chr6:41040923..41040952,+!p2@NFYA!0.74!12.88!NFYA;;chr1:151254738..151254787,+!p1@ZNF687!0.73!45.50!ZNF687;;chr14:64971288..64971316,-!p2@ZBTB25!0.73!14.59!ZBTB25;;chr9:137217986..137218049,+!p3@RXRA!0.73!13.74!RXRA;;chr18:3449330..3449344,+!p10@TGIF1!0.73!6.01!TGIF1;;chr17:48072574..48072597,-!p1@DLX3!0.72!4.29!DLX3;;chr9:126774018..126774055,+!p1@LHX2!0.72!4.29!LHX2;;chr3:181429704..181429722,+!p1@SOX2!0.72!4.29!SOX2;;chr6:126070748..126070768,+!p2@HEY2!0.72!4.29!HEY2;;chr6:135513595..135513617,+!p4@MYB!0.72!4.29!MYB;;chr10:8100452..8100463,+!p20@GATA3!0.72!4.29!GATA3;;chr11:101000445..101000465,-!p5@PGR!0.72!4.29!PGR;;chr11:129245526..129245553,+!p1@BARX2!0.72!4.29!BARX2;;chr1:10856694..10856715,-!p3@CASZ1!0.72!4.29!CASZ1;;chr1:151804244..151804310,-!p1@RORC!0.72!4.29!RORC;;chr1:154975229..154975247,+!p6@ZBTB7B!0.72!4.29!ZBTB7B;;chr20:18037473..18037494,-!p3@OVOL2!0.72!4.29!OVOL2;;chr20:55205825..55205847,+!p2@TFAP2C!0.72!4.29!TFAP2C;;chr20:62601243..62601291,-!p1@ZNF512B!0.71!45.50!ZNF512B;;chr6:20402102..20402152,+!p1@E2F3!0.71!18.89!E2F3;;chr11:47270436..47270464,+!p2@NR1H3!0.71!9.44!NR1H3;;chr17:42299455..42299485,-!p12@UBTF!0.71!6.01!UBTF;;chr11:62521614..62521646,-!p1@ZBTB3!0.70!23.18!ZBTB3;;chr19:12721513..12721572,-!p1@ZNF490!0.70!18.89!ZNF490;;chr19:12551785..12551823,-!p1@ZNF443!0.70!6.87!ZNF443;;chr15:96876966..96877017,+!p12@NR2F2!0.70!6.01!NR2F2;;chr17:38465441..38465481,+!p6@RARA!0.70!5.15!RARA;;chr1:202777535..202777556,-!p1@KDM5B!0.68!146.80!KDM5B;;chr13:41593425..41593480,-!p1@ELF1!0.68!27.47!ELF1;;chr8:67525443..67525459,-!p2@MYBL1!0.68!6.01!MYBL1;;chr16:88519669..88519726,+!p1@ZFPM1!0.67!37.77!ZFPM1;;chr19:12551824..12551846,-!p2@ZNF443!0.67!5.15!ZNF443;;chr20:46130727..46130734,+!p4@NCOA3!0.67!5.15!NCOA3;;chr2:10091815..10091864,+!p1@GRHL1!0.67!5.15!GRHL1;;chr22:31742303..31742350,-!p1@PATZ1!0.66!45.50!PATZ1;;chr6:15246200..15246214,+!p2@JARID2!0.66!11.16!JARID2;;chr6:135502408..135502459,+!p2@MYB!0.66!4.29!MYB;;chr6:21593973..21593988,+!p1@SOX4!0.65!145.08!SOX4;;chr20:48807875..48807982,+!p2@CEBPB!0.65!89.28!CEBPB;;chr19:42580274..42580375,+!p1@ZNF574!0.65!46.36!ZNF574;;chr12:2986275..2986363,-!p1@FOXM1!0.65!40.35!FOXM1;;chr20:32274179..32274213,-!p1@E2F1!0.65!26.61!E2F1;;chr19:12146483..12146546,-!p1@ZNF433!0.65!14.59!ZNF433;;chr8:145669791..145669834,-!p1@TONSL!0.65!11.16!TONSL;;chr5:169532896..169532904,+!p1@FOXI1!0.65!3.43!FOXI1;;chr6:152129265..152129276,+!p13@ESR1!0.65!3.43!ESR1;;chr6:152130240..152130274,+!p9@ESR1!0.65!3.43!ESR1;;chr7:101917407..101917443,+!p3@CUX1!0.65!3.43!CUX1;;chr7:101917447..101917479,+!p4@CUX1!0.65!3.43!CUX1;;chr7:27190547..27190591,-!p1@HOXA6!0.65!3.43!HOXA6;;chr7:73038839..73038862,-!p1@MLXIPL!0.65!3.43!MLXIPL;;chr8:144512897..144512903,-!p1@MAFA!0.65!3.43!MAFA;;chr15:96880438..96880445,+!p23@NR2F2!0.65!3.43!NR2F2;;chr17:80797863..80797874,-!p2@ZNF750!0.65!3.43!ZNF750;;chr19:3574330..3574393,+!p2@HMG20B!0.65!3.43!HMG20B;;chr1:3569072..3569093,+!p1@TP73!0.65!3.43!TP73;;chr1:3569135..3569150,+!p3@TP73!0.65!3.43!TP73;;chr20:18038486..18038520,-!p2@OVOL2!0.65!3.43!OVOL2;;chr21:38071430..38071456,+!p1@SIM2!0.65!3.43!SIM2;;chr10:8097357..8097368,+!p15@GATA3!0.65!3.43!GATA3;;chr11:101000537..101000553,-!p1@PGR!0.65!3.43!PGR;;chr12:53625846..53625861,-!p6@RARG!0.65!3.43!RARG;;chr12:54393880..54393962,+!p1@HOXC9!0.65!3.43!HOXC9;;chr2:238592039..238592054,+!p4@LRRFIP1!0.65!3.43!LRRFIP1;;chr3:128207349..1282073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| |||
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|fonse_cell_line=FF:0100816,FF:0101120 | |fonse_cell_line=FF:0100816,FF:0101120 | ||
|fonse_cell_line_closure=FF:0100816,FF:0101120 | |fonse_cell_line_closure=FF:0100816,FF:0101120 | ||
Line 66: | Line 42: | ||
|fonse_treatment=EFO:0000369,FF:0000330,FF:0000426,FF:13163-141B4 | |fonse_treatment=EFO:0000369,FF:0000330,FF:0000426,FF:13163-141B4 | ||
|fonse_treatment_closure=EFO:0000369,FF:0000330,FF:0000426,FF:13163-141B4 | |fonse_treatment_closure=EFO:0000369,FF:0000330,FF:0000426,FF:13163-141B4 | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/MCF7%2520breast%2520cancer%2520cell%2520line%2520response%2520to%2520EGF1%252c%252000hr00min%252c%2520biol_rep3.CNhs12703.13163-141B4.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/MCF7%2520breast%2520cancer%2520cell%2520line%2520response%2520to%2520EGF1%252c%252000hr00min%252c%2520biol_rep3.CNhs12703.13163-141B4.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/MCF7%2520breast%2520cancer%2520cell%2520line%2520response%2520to%2520EGF1%252c%252000hr00min%252c%2520biol_rep3.CNhs12703.13163-141B4.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.timecourse.hCAGE/MCF7%2520breast%2520cancer%2520cell%2520line%2520response%2520to%2520EGF1%252c%252000hr00min%252c%2520biol_rep3.CNhs12703.13163-141B4.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.timecourse.hCAGE/MCF7%2520breast%2520cancer%2520cell%2520line%2520response%2520to%2520EGF1%252c%252000hr00min%252c%2520biol_rep3.CNhs12703.13163-141B4.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:13163-141B4 | |||
|is_a=EFO:0002091;;FF:0000426 | |||
|is_obsolete= | |||
|library_id=CNhs12703 | |||
|library_id_phase_based=2:CNhs12703 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;13163 | |||
|microRNAs_nonnovel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer/#/human#srna;sample;SRhi10063.GATCAG.13163 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;13163 | |||
|microRNAs_novel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer_novel/#/human#srna;sample;SRhi10063.GATCAG.13163 | |||
|name=MCF7 breast cancer cell line response to EGF1 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs12703,LSID953,release011,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.273767184513731,0.269159331776533,0.46585573801159,0.787537547690514,0,0,0,0,0,0,0,0,0,0,0,0,0,0.115836321428105,0,0,0,0,0,1.62932023107447,0,0,1.03541649780683,0,0,0,0,0,0,0,0,0,0,0,0,0.534666457288012,0.434085214600117,0,0,0,0,0,0,0,0.110364644775432,0,0,0,0.269159331776533,0,0,0,1.49154142494865,0,0,0.33674158738702,0,0,0,0,0,0,0,0,0.269159331776533,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.180402944591253,0,0,0,0.210712504964708,-0.211197402695869,0,0,0,0,-0.0980353512377064,0.390572397482485,0,0,0,0,0,0,0.723655189067339,0,0,0,0,0,0,0,0,0,0,-0.096373593922461,0,0,0,0.3834800694479,0.467611607111075,0,0,0.269159331776533,0,0,0 | |||
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| |||
|rna_box=141 | |||
|rna_catalog_number= | |||
|rna_concentration=0.86 | |||
|rna_extraction_protocol=Repurified by minelute | |||
|rna_lot_number= | |||
|rna_od260/230=1.79 | |||
|rna_od260/280=2.02 | |||
|rna_position=B4 | |||
|rna_rin= | |||
|rna_sample_type= | |||
|rna_tube_id=141B4 | |||
|rna_weight_ug=8.57 | |||
|rnaseq_library_id=SRhi10063.GATCAG | |||
|sample_age= | |||
|sample_category=time courses | |||
|sample_cell_catalog= | |||
|sample_cell_line=MCF7 | |||
|sample_cell_lot= | |||
|sample_cell_type=mammary gland epithelial cell | |||
|sample_collaboration=Mariko Okada Hatakeyama (RIKEN RCAI) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)=rep3 | |||
|sample_ethnicity= | |||
|sample_experimental_condition=MCF7 breast cancer cell line response to Epidermal Growth Factor 1 | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.8335202393372e-245!GO:0043231;intracellular membrane-bound organelle;3.01433145204656e-215!GO:0043227;membrane-bound organelle;4.09133416889602e-215!GO:0043226;organelle;1.52260401992905e-209!GO:0043229;intracellular organelle;5.29858372818803e-209!GO:0005737;cytoplasm;2.27006988823242e-166!GO:0044422;organelle part;1.27401331524055e-147!GO:0044446;intracellular organelle part;2.04599033749516e-146!GO:0044444;cytoplasmic part;1.89285359926928e-127!GO:0032991;macromolecular complex;2.26853410068739e-95!GO:0044237;cellular metabolic process;4.96416444710186e-95!GO:0005634;nucleus;2.52211244804088e-93!GO:0044238;primary metabolic process;3.05773358204433e-91!GO:0030529;ribonucleoprotein complex;1.46310508088769e-83!GO:0043170;macromolecule metabolic process;4.04115760710401e-82!GO:0005739;mitochondrion;9.72870805290754e-77!GO:0044428;nuclear part;5.85208676944962e-76!GO:0043233;organelle lumen;1.78194020388566e-72!GO:0031974;membrane-enclosed lumen;1.78194020388566e-72!GO:0003723;RNA binding;9.99701585048493e-67!GO:0005515;protein binding;1.22340477744511e-62!GO:0005840;ribosome;1.0100645293448e-54!GO:0043283;biopolymer metabolic process;4.02404306878696e-52!GO:0031090;organelle membrane;8.09867562055121e-51!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.05995303349569e-50!GO:0006396;RNA processing;5.01031418363404e-49!GO:0044429;mitochondrial part;5.01031418363404e-49!GO:0003735;structural constituent of ribosome;5.9419737602561e-48!GO:0006412;translation;7.44310182659544e-48!GO:0043234;protein complex;9.77761440443024e-48!GO:0031981;nuclear lumen;1.87477602816928e-46!GO:0010467;gene expression;5.25201415552819e-46!GO:0031967;organelle envelope;6.08156414859604e-45!GO:0031975;envelope;1.49932235218857e-44!GO:0015031;protein transport;5.26174306358508e-42!GO:0033036;macromolecule localization;4.54651429502176e-41!GO:0033279;ribosomal subunit;1.25267533646857e-40!GO:0044249;cellular biosynthetic process;3.13823100896628e-40!GO:0009058;biosynthetic process;5.27121551594412e-40!GO:0016043;cellular component organization and biogenesis;8.3209269437286e-40!GO:0006259;DNA metabolic process;1.34417737321735e-39!GO:0019538;protein metabolic process;2.4316887292008e-38!GO:0008104;protein localization;7.74226946010479e-38!GO:0045184;establishment of protein localization;1.39198704146438e-37!GO:0009059;macromolecule biosynthetic process;7.11484261343888e-37!GO:0016071;mRNA metabolic process;7.58409753365209e-37!GO:0005829;cytosol;4.31121350812537e-35!GO:0044260;cellular macromolecule metabolic process;5.62844454743458e-35!GO:0044267;cellular protein metabolic process;1.72123992631131e-34!GO:0008380;RNA splicing;6.52054441913056e-33!GO:0006397;mRNA processing;1.40947223097168e-32!GO:0065003;macromolecular complex assembly;1.47917357162692e-32!GO:0005740;mitochondrial envelope;1.80255927329894e-32!GO:0043228;non-membrane-bound organelle;2.9317819377395e-32!GO:0043232;intracellular non-membrane-bound organelle;2.9317819377395e-32!GO:0019866;organelle inner membrane;6.73034247995456e-32!GO:0031966;mitochondrial membrane;1.09371479841077e-30!GO:0006996;organelle organization and biogenesis;8.9650403848997e-30!GO:0005743;mitochondrial inner membrane;1.06180909679197e-29!GO:0005654;nucleoplasm;2.02355760018475e-29!GO:0022607;cellular component assembly;3.88668782600029e-28!GO:0005830;cytosolic ribosome (sensu Eukaryota);4.07923909487093e-28!GO:0046907;intracellular transport;5.40266320067395e-28!GO:0003676;nucleic acid binding;7.13931963138247e-28!GO:0022613;ribonucleoprotein complex biogenesis and assembly;6.72087623773102e-27!GO:0007049;cell cycle;5.26909944233885e-26!GO:0006886;intracellular protein transport;5.35164492903361e-26!GO:0044451;nucleoplasm part;3.34865371034245e-24!GO:0005681;spliceosome;8.5615932006021e-24!GO:0006119;oxidative phosphorylation;2.86863268408383e-23!GO:0044445;cytosolic part;6.80894431977934e-23!GO:0015934;large ribosomal subunit;9.37630104361197e-22!GO:0016070;RNA metabolic process;2.19044303038327e-21!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;2.32311786231038e-21!GO:0000166;nucleotide binding;3.030222163075e-21!GO:0016817;hydrolase activity, acting on acid anhydrides;3.13530468449858e-21!GO:0016462;pyrophosphatase activity;3.13530468449858e-21!GO:0006974;response to DNA damage stimulus;3.39000866596285e-21!GO:0031980;mitochondrial lumen;8.50595544692897e-21!GO:0005759;mitochondrial matrix;8.50595544692897e-21!GO:0017111;nucleoside-triphosphatase activity;1.27562916300753e-20!GO:0022402;cell cycle process;2.77264585695789e-20!GO:0044455;mitochondrial membrane part;2.98644670859015e-20!GO:0015935;small ribosomal subunit;5.70115250809296e-20!GO:0012505;endomembrane system;1.16889248188843e-19!GO:0016874;ligase activity;1.30912145384327e-19!GO:0051649;establishment of cellular localization;4.90173051643838e-19!GO:0005694;chromosome;6.88806130659081e-19!GO:0006512;ubiquitin cycle;1.8228651009565e-18!GO:0051641;cellular localization;3.04762812338164e-18!GO:0006281;DNA repair;3.71895290892723e-18!GO:0005730;nucleolus;4.77390429537253e-18!GO:0051186;cofactor metabolic process;8.24786751336116e-18!GO:0044427;chromosomal part;1.0064865208227e-17!GO:0000278;mitotic cell cycle;2.44187495752891e-17!GO:0051276;chromosome organization and biogenesis;2.63552666634002e-17!GO:0005746;mitochondrial respiratory chain;3.06039019975723e-16!GO:0009719;response to endogenous stimulus;3.12902165644345e-16!GO:0044265;cellular macromolecule catabolic process;3.18229398260491e-16!GO:0000502;proteasome complex (sensu Eukaryota);7.64313156121629e-16!GO:0005761;mitochondrial ribosome;1.25149142209868e-15!GO:0000313;organellar ribosome;1.25149142209868e-15!GO:0006457;protein folding;1.73864720539919e-15!GO:0006325;establishment and/or maintenance of chromatin architecture;1.80873817650412e-15!GO:0032553;ribonucleotide binding;2.47453307377884e-15!GO:0032555;purine ribonucleotide binding;2.47453307377884e-15!GO:0043285;biopolymer catabolic process;2.9640879387372e-15!GO:0008134;transcription factor binding;3.54335676471595e-15!GO:0022618;protein-RNA complex assembly;4.29820438868453e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);4.6556417998537e-15!GO:0048770;pigment granule;5.1225848565724e-15!GO:0042470;melanosome;5.1225848565724e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;6.89249428406771e-15!GO:0006323;DNA packaging;9.94934304083676e-15!GO:0016887;ATPase activity;1.08943793812793e-14!GO:0005783;endoplasmic reticulum;1.20266077826535e-14!GO:0008135;translation factor activity, nucleic acid binding;1.20791458916329e-14!GO:0050136;NADH dehydrogenase (quinone) activity;1.32618850388844e-14!GO:0003954;NADH dehydrogenase activity;1.32618850388844e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.32618850388844e-14!GO:0006732;coenzyme metabolic process;1.32759310753736e-14!GO:0044248;cellular catabolic process;1.37194198801135e-14!GO:0017076;purine nucleotide binding;1.37805941055391e-14!GO:0006260;DNA replication;1.63853507751122e-14!GO:0042623;ATPase activity, coupled;1.83065126730782e-14!GO:0044432;endoplasmic reticulum part;2.71687045550337e-14!GO:0009057;macromolecule catabolic process;3.11124264506429e-14!GO:0005524;ATP binding;4.36265804197601e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;5.24381564311176e-14!GO:0032559;adenyl ribonucleotide binding;5.48982640482334e-14!GO:0031965;nuclear membrane;5.98146796877731e-14!GO:0000398;nuclear mRNA splicing, via spliceosome;7.06693902525072e-14!GO:0000375;RNA splicing, via transesterification reactions;7.06693902525072e-14!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;7.06693902525072e-14!GO:0019941;modification-dependent protein catabolic process;7.79776361413023e-14!GO:0043632;modification-dependent macromolecule catabolic process;7.79776361413023e-14!GO:0022403;cell cycle phase;8.96955922645012e-14!GO:0044257;cellular protein catabolic process;9.31639330234525e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.23125499190366e-13!GO:0006511;ubiquitin-dependent protein catabolic process;1.70506998197125e-13!GO:0005635;nuclear envelope;2.17993350211175e-13!GO:0000087;M phase of mitotic cell cycle;3.08188315198021e-13!GO:0007067;mitosis;3.72051828090432e-13!GO:0030554;adenyl nucleotide binding;4.82727930954792e-13!GO:0051082;unfolded protein binding;4.90068672958256e-13!GO:0051301;cell division;5.16858547060701e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;9.80345290740871e-13!GO:0042775;organelle ATP synthesis coupled electron transport;9.88627076326788e-13!GO:0042773;ATP synthesis coupled electron transport;9.88627076326788e-13!GO:0030964;NADH dehydrogenase complex (quinone);1.37372170377071e-12!GO:0045271;respiratory chain complex I;1.37372170377071e-12!GO:0005747;mitochondrial respiratory chain complex I;1.37372170377071e-12!GO:0006333;chromatin assembly or disassembly;1.48669593301012e-12!GO:0065004;protein-DNA complex assembly;1.65142959238365e-12!GO:0006605;protein targeting;3.01122387734522e-12!GO:0042254;ribosome biogenesis and assembly;4.68723656164772e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;4.7719258401164e-12!GO:0016604;nuclear body;7.4149463276786e-12!GO:0042175;nuclear envelope-endoplasmic reticulum network;8.25917435401143e-12!GO:0043412;biopolymer modification;9.72029222614179e-12!GO:0006399;tRNA metabolic process;1.2140076422555e-11!GO:0005789;endoplasmic reticulum membrane;1.28917986996338e-11!GO:0051726;regulation of cell cycle;1.41376798511475e-11!GO:0000785;chromatin;1.46800303785609e-11!GO:0030163;protein catabolic process;1.54344393419588e-11!GO:0044453;nuclear membrane part;1.8827799785762e-11!GO:0000279;M phase;1.94847255957167e-11!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.40899122857202e-11!GO:0000074;regulation of progression through cell cycle;3.34608049209954e-11!GO:0051188;cofactor biosynthetic process;3.89062282167474e-11!GO:0004386;helicase activity;6.92829564908341e-11!GO:0048193;Golgi vesicle transport;9.37666126760332e-11!GO:0006913;nucleocytoplasmic transport;1.9682887450344e-10!GO:0006163;purine nucleotide metabolic process;2.29948954803243e-10!GO:0005794;Golgi apparatus;2.50811834161476e-10!GO:0008026;ATP-dependent helicase activity;2.67671433805995e-10!GO:0016192;vesicle-mediated transport;3.51032267872264e-10!GO:0009259;ribonucleotide metabolic process;3.58279619542085e-10!GO:0003743;translation initiation factor activity;3.94560608166211e-10!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;3.96818784769335e-10!GO:0051169;nuclear transport;5.8309676115788e-10!GO:0003712;transcription cofactor activity;5.96852414662023e-10!GO:0006464;protein modification process;7.42837284962734e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;7.42837284962734e-10!GO:0015986;ATP synthesis coupled proton transport;8.81226173632594e-10!GO:0015985;energy coupled proton transport, down electrochemical gradient;8.81226173632594e-10!GO:0006366;transcription from RNA polymerase II promoter;1.00650574146404e-09!GO:0019829;cation-transporting ATPase activity;1.00650574146404e-09!GO:0006164;purine nucleotide biosynthetic process;1.04430855508259e-09!GO:0006334;nucleosome assembly;1.17985144924306e-09!GO:0009150;purine ribonucleotide metabolic process;1.30280460940571e-09!GO:0005643;nuclear pore;1.38163019675092e-09!GO:0009108;coenzyme biosynthetic process;1.45098285423026e-09!GO:0008639;small protein conjugating enzyme activity;1.53431723846443e-09!GO:0009199;ribonucleoside triphosphate metabolic process;1.68811982535588e-09!GO:0009260;ribonucleotide biosynthetic process;2.2386280542068e-09!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.37336575304538e-09!GO:0009144;purine nucleoside triphosphate metabolic process;2.37336575304538e-09!GO:0009142;nucleoside triphosphate biosynthetic process;2.37336575304538e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.37336575304538e-09!GO:0009141;nucleoside triphosphate metabolic process;2.60309506424094e-09!GO:0019787;small conjugating protein ligase activity;2.68656538484309e-09!GO:0031497;chromatin assembly;2.9748048097921e-09!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;3.34901994349305e-09!GO:0009145;purine nucleoside triphosphate biosynthetic process;3.34901994349305e-09!GO:0006413;translational initiation;3.63237083431557e-09!GO:0004842;ubiquitin-protein ligase activity;4.17384918162839e-09!GO:0012501;programmed cell death;5.42047675510697e-09!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;5.61767224492024e-09!GO:0009152;purine ribonucleotide biosynthetic process;5.72480831541161e-09!GO:0006446;regulation of translational initiation;6.3799553745085e-09!GO:0015078;hydrogen ion transmembrane transporter activity;9.27862477477121e-09!GO:0006915;apoptosis;9.32499710461825e-09!GO:0006754;ATP biosynthetic process;9.44729699449052e-09!GO:0006753;nucleoside phosphate metabolic process;9.44729699449052e-09!GO:0046034;ATP metabolic process;9.68704927064089e-09!GO:0016568;chromatin modification;9.89083377123668e-09!GO:0009055;electron carrier activity;9.92799649521701e-09!GO:0050657;nucleic acid transport;1.02484350556791e-08!GO:0051236;establishment of RNA localization;1.02484350556791e-08!GO:0050658;RNA transport;1.02484350556791e-08!GO:0006403;RNA localization;1.39072522440023e-08!GO:0003697;single-stranded DNA binding;1.44957936172226e-08!GO:0008565;protein transporter activity;1.45520248490252e-08!GO:0043687;post-translational protein modification;2.03793821999841e-08!GO:0006461;protein complex assembly;2.21337261468056e-08!GO:0016779;nucleotidyltransferase activity;2.60442796843862e-08!GO:0065002;intracellular protein transport across a membrane;2.62615831260323e-08!GO:0009056;catabolic process;2.73335877945015e-08!GO:0006364;rRNA processing;2.86043973473903e-08!GO:0016072;rRNA metabolic process;3.90202152112344e-08!GO:0009117;nucleotide metabolic process;4.16581582698087e-08!GO:0016607;nuclear speck;5.05583270272757e-08!GO:0046930;pore complex;5.15838129788319e-08!GO:0009060;aerobic respiration;6.20201398864518e-08!GO:0016881;acid-amino acid ligase activity;6.71534546941643e-08!GO:0008219;cell death;7.09853412265147e-08!GO:0016265;death;7.09853412265147e-08!GO:0016469;proton-transporting two-sector ATPase complex;7.52425666528675e-08!GO:0006261;DNA-dependent DNA replication;7.52425666528675e-08!GO:0005793;ER-Golgi intermediate compartment;9.60984893870555e-08!GO:0007005;mitochondrion organization and biogenesis;1.06603149562189e-07!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.31180428292953e-07!GO:0017038;protein import;1.47505470581039e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.63576568125222e-07!GO:0032446;protein modification by small protein conjugation;1.7235616014186e-07!GO:0043566;structure-specific DNA binding;2.07406606772567e-07!GO:0006752;group transfer coenzyme metabolic process;2.1139655130026e-07!GO:0016787;hydrolase activity;2.46075089198001e-07!GO:0030532;small nuclear ribonucleoprotein complex;2.79023983779197e-07!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;2.98998005542814e-07!GO:0004812;aminoacyl-tRNA ligase activity;2.98998005542814e-07!GO:0016875;ligase activity, forming carbon-oxygen bonds;2.98998005542814e-07!GO:0005667;transcription factor complex;3.09984242889939e-07!GO:0045259;proton-transporting ATP synthase complex;3.54377955507428e-07!GO:0016567;protein ubiquitination;4.12090390931856e-07!GO:0016740;transferase activity;8.52738844751473e-07!GO:0043038;amino acid activation;8.52738844751473e-07!GO:0006418;tRNA aminoacylation for protein translation;8.52738844751473e-07!GO:0043039;tRNA aminoacylation;8.52738844751473e-07!GO:0015077;monovalent inorganic cation transmembrane transporter activity;8.52738844751473e-07!GO:0051028;mRNA transport;8.74794476652724e-07!GO:0045333;cellular respiration;1.00953538874576e-06!GO:0005768;endosome;1.48409796306523e-06!GO:0050794;regulation of cellular process;1.63836953854586e-06!GO:0016564;transcription repressor activity;2.17611930831772e-06!GO:0043623;cellular protein complex assembly;2.40099588722775e-06!GO:0006099;tricarboxylic acid cycle;3.24830371877761e-06!GO:0046356;acetyl-CoA catabolic process;3.24830371877761e-06!GO:0016023;cytoplasmic membrane-bound vesicle;3.82421460941287e-06!GO:0000245;spliceosome assembly;3.93340187296378e-06!GO:0048475;coated membrane;4.11902105298899e-06!GO:0030117;membrane coat;4.11902105298899e-06!GO:0005839;proteasome core complex (sensu Eukaryota);4.6441164534388e-06!GO:0006084;acetyl-CoA metabolic process;5.19493643948287e-06!GO:0031988;membrane-bound vesicle;5.41429519905214e-06!GO:0005762;mitochondrial large ribosomal subunit;5.45428953305141e-06!GO:0000315;organellar large ribosomal subunit;5.45428953305141e-06!GO:0015630;microtubule cytoskeleton;5.88327635379972e-06!GO:0008033;tRNA processing;6.43002640407966e-06!GO:0000786;nucleosome;7.23736335906784e-06!GO:0031324;negative regulation of cellular metabolic process;8.53259352276824e-06!GO:0005819;spindle;9.71214702213951e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.16838919873453e-05!GO:0015992;proton transport;1.25821526713434e-05!GO:0003724;RNA helicase activity;1.44416698529005e-05!GO:0016563;transcription activator activity;1.46655879491186e-05!GO:0044431;Golgi apparatus part;1.47816817016945e-05!GO:0006818;hydrogen transport;1.63773536927388e-05!GO:0009165;nucleotide biosynthetic process;1.68219648078259e-05!GO:0051329;interphase of mitotic cell cycle;1.68219648078259e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.81730804047556e-05!GO:0008094;DNA-dependent ATPase activity;1.8205825942589e-05!GO:0051168;nuclear export;1.85016362593832e-05!GO:0003713;transcription coactivator activity;2.10367434062761e-05!GO:0004298;threonine endopeptidase activity;2.26592659905136e-05!GO:0003899;DNA-directed RNA polymerase activity;2.83735688534209e-05!GO:0051187;cofactor catabolic process;2.84253674982862e-05!GO:0006888;ER to Golgi vesicle-mediated transport;2.85898471055588e-05!GO:0030120;vesicle coat;3.06398387549379e-05!GO:0030662;coated vesicle membrane;3.06398387549379e-05!GO:0051325;interphase;3.06678381653815e-05!GO:0009109;coenzyme catabolic process;3.15364954815784e-05!GO:0051427;hormone receptor binding;3.22141143760421e-05!GO:0019222;regulation of metabolic process;3.42768098991191e-05!GO:0000775;chromosome, pericentric region;3.75437365147388e-05!GO:0031982;vesicle;3.90860886934594e-05!GO:0000314;organellar small ribosomal subunit;3.97636546627824e-05!GO:0005763;mitochondrial small ribosomal subunit;3.97636546627824e-05!GO:0005657;replication fork;4.22386060484411e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;4.25597068236327e-05!GO:0031410;cytoplasmic vesicle;4.44551235811125e-05!GO:0007051;spindle organization and biogenesis;4.76224560478788e-05!GO:0000151;ubiquitin ligase complex;4.88862946745361e-05!GO:0009892;negative regulation of metabolic process;5.00315893156189e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;5.01243154984548e-05!GO:0008654;phospholipid biosynthetic process;5.05131985030883e-05!GO:0006414;translational elongation;5.76772342507647e-05!GO:0016491;oxidoreductase activity;6.12421665132688e-05!GO:0042802;identical protein binding;6.12421665132688e-05!GO:0051170;nuclear import;6.58185586658743e-05!GO:0006091;generation of precursor metabolites and energy;7.28245630820118e-05!GO:0035257;nuclear hormone receptor binding;7.41984037860948e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.62762809880578e-05!GO:0003714;transcription corepressor activity;8.6696227391691e-05!GO:0003924;GTPase activity;8.90282827939309e-05!GO:0043067;regulation of programmed cell death;9.71678346389185e-05!GO:0000075;cell cycle checkpoint;9.79715861683218e-05!GO:0016741;transferase activity, transferring one-carbon groups;9.96438074289363e-05!GO:0042981;regulation of apoptosis;0.00010898005423164!GO:0006606;protein import into nucleus;0.000117536245321287!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000119689003767917!GO:0008168;methyltransferase activity;0.000123694010552321!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000132318108728046!GO:0015399;primary active transmembrane transporter activity;0.000132318108728046!GO:0006613;cotranslational protein targeting to membrane;0.000133975579822494!GO:0005773;vacuole;0.000134104417867807!GO:0051246;regulation of protein metabolic process;0.000142341544511417!GO:0008186;RNA-dependent ATPase activity;0.000151534188154285!GO:0005813;centrosome;0.000154591745608181!GO:0006401;RNA catabolic process;0.000155900744224071!GO:0045786;negative regulation of progression through cell cycle;0.000171643657224278!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00018857146118816!GO:0048523;negative regulation of cellular process;0.000188776143054569!GO:0044440;endosomal part;0.000213326227327077!GO:0010008;endosome membrane;0.000213326227327077!GO:0006402;mRNA catabolic process;0.000218591009655846!GO:0005770;late endosome;0.000229711155475233!GO:0003684;damaged DNA binding;0.000234875215940679!GO:0006793;phosphorus metabolic process;0.000234875215940679!GO:0006796;phosphate metabolic process;0.000234875215940679!GO:0005815;microtubule organizing center;0.00025253646732441!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000329935296085891!GO:0030867;rough endoplasmic reticulum membrane;0.000378053416104147!GO:0004004;ATP-dependent RNA helicase activity;0.000400739222793317!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000439364489378669!GO:0015980;energy derivation by oxidation of organic compounds;0.000442526912038688!GO:0016481;negative regulation of transcription;0.000463374803804883!GO:0005769;early endosome;0.000475251235771903!GO:0005798;Golgi-associated vesicle;0.000582637540725286!GO:0043021;ribonucleoprotein binding;0.000607372485312812!GO:0046474;glycerophospholipid biosynthetic process;0.000614964049875843!GO:0003682;chromatin binding;0.000619317044628783!GO:0006916;anti-apoptosis;0.000627391493988098!GO:0043069;negative regulation of programmed cell death;0.000646566592295322!GO:0016126;sterol biosynthetic process;0.000648407704764642!GO:0005048;signal sequence binding;0.000668931671634762!GO:0033116;ER-Golgi intermediate compartment membrane;0.000688335834155756!GO:0016310;phosphorylation;0.000703073732656824!GO:0000323;lytic vacuole;0.000715812738759711!GO:0005764;lysosome;0.000715812738759711!GO:0003746;translation elongation factor activity;0.000715812738759711!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.000715812738759711!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.000715812738759711!GO:0006839;mitochondrial transport;0.000732341372299871!GO:0003678;DNA helicase activity;0.000743135617611028!GO:0046489;phosphoinositide biosynthetic process;0.00075247385607807!GO:0043492;ATPase activity, coupled to movement of substances;0.000766371652777363!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000769275884571256!GO:0050789;regulation of biological process;0.000796141643897426!GO:0004518;nuclease activity;0.000805167923871757!GO:0043681;protein import into mitochondrion;0.000839897700130378!GO:0051789;response to protein stimulus;0.000843330026235824!GO:0006986;response to unfolded protein;0.000843330026235824!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000845263829903563!GO:0051087;chaperone binding;0.000862540608552484!GO:0043284;biopolymer biosynthetic process;0.00090493444798667!GO:0016853;isomerase activity;0.000936322215523251!GO:0000139;Golgi membrane;0.000936322215523251!GO:0006350;transcription;0.000982981600563257!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000987659905264287!GO:0051920;peroxiredoxin activity;0.00102900805710616!GO:0005684;U2-dependent spliceosome;0.00103766972215082!GO:0032508;DNA duplex unwinding;0.00113057380496291!GO:0032392;DNA geometric change;0.00113057380496291!GO:0019899;enzyme binding;0.00115649227874878!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00115649227874878!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00115649227874878!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00115649227874878!GO:0048471;perinuclear region of cytoplasm;0.00117382919686302!GO:0006695;cholesterol biosynthetic process;0.00120633231140963!GO:0006302;double-strand break repair;0.00123303463999646!GO:0005525;GTP binding;0.00123886450719547!GO:0006405;RNA export from nucleus;0.00124053345676247!GO:0043066;negative regulation of apoptosis;0.00132727740911187!GO:0031323;regulation of cellular metabolic process;0.00133589896690091!GO:0003729;mRNA binding;0.00137489036324924!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00140688353160637!GO:0016363;nuclear matrix;0.00141526223442023!GO:0006352;transcription initiation;0.00142446782267438!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00145604548990358!GO:0005788;endoplasmic reticulum lumen;0.00152622063433219!GO:0003711;transcription elongation regulator activity;0.00156255634781299!GO:0005885;Arp2/3 protein complex;0.00156930570357645!GO:0046983;protein dimerization activity;0.00160563574072677!GO:0006270;DNA replication initiation;0.00180222900370244!GO:0048519;negative regulation of biological process;0.00187282621552277!GO:0006284;base-excision repair;0.00190458394325148!GO:0030176;integral to endoplasmic reticulum membrane;0.00196744470587828!GO:0046483;heterocycle metabolic process;0.00199385107854172!GO:0006383;transcription from RNA polymerase III promoter;0.00199395565737599!GO:0051252;regulation of RNA metabolic process;0.00205343857064461!GO:0008250;oligosaccharyl transferase complex;0.00214630015416125!GO:0031968;organelle outer membrane;0.00232054296292881!GO:0022890;inorganic cation transmembrane transporter activity;0.00232671997954519!GO:0044262;cellular carbohydrate metabolic process;0.00232847712626334!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00232847712626334!GO:0006268;DNA unwinding during replication;0.00236927281753545!GO:0031252;leading edge;0.00245212790732007!GO:0045454;cell redox homeostasis;0.00248610410321769!GO:0065009;regulation of a molecular function;0.00267394733835234!GO:0004527;exonuclease activity;0.0027400384645545!GO:0006612;protein targeting to membrane;0.00275120182567814!GO:0007264;small GTPase mediated signal transduction;0.00280499724639753!GO:0030880;RNA polymerase complex;0.00287868319598316!GO:0006611;protein export from nucleus;0.002881276424153!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.00291879298600236!GO:0001558;regulation of cell growth;0.00293307656051445!GO:0019867;outer membrane;0.00305071467306747!GO:0004576;oligosaccharyl transferase activity;0.00314503130191584!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0032330642719535!GO:0006650;glycerophospholipid metabolic process;0.00339350639612275!GO:0000059;protein import into nucleus, docking;0.00349072733560004!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.00355514649731751!GO:0003690;double-stranded DNA binding;0.00360953540530262!GO:0048487;beta-tubulin binding;0.00361799997881183!GO:0030384;phosphoinositide metabolic process;0.00362021089213251!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00365181441004017!GO:0015002;heme-copper terminal oxidase activity;0.00365181441004017!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00365181441004017!GO:0004129;cytochrome-c oxidase activity;0.00365181441004017!GO:0043488;regulation of mRNA stability;0.00368845197952358!GO:0043487;regulation of RNA stability;0.00368845197952358!GO:0005637;nuclear inner membrane;0.00377234111279549!GO:0006506;GPI anchor biosynthetic process;0.00379537512519546!GO:0005741;mitochondrial outer membrane;0.00419102932567216!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00463795860351161!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.004785775802621!GO:0005905;coated pit;0.00496579417308407!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00496579417308407!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00505277977819977!GO:0007006;mitochondrial membrane organization and biogenesis;0.00505277977819977!GO:0007088;regulation of mitosis;0.00527445249037514!GO:0035258;steroid hormone receptor binding;0.00530064380482762!GO:0043414;biopolymer methylation;0.00535501767357502!GO:0006733;oxidoreduction coenzyme metabolic process;0.0053686606925004!GO:0006595;polyamine metabolic process;0.00541347350705535!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00569272552718018!GO:0006289;nucleotide-excision repair;0.00575148761211742!GO:0006730;one-carbon compound metabolic process;0.00579028496800316!GO:0046519;sphingoid metabolic process;0.00583600384476085!GO:0008287;protein serine/threonine phosphatase complex;0.00585911556329084!GO:0006672;ceramide metabolic process;0.00593171171238273!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00595626423048486!GO:0000428;DNA-directed RNA polymerase complex;0.00595626423048486!GO:0030137;COPI-coated vesicle;0.00595626423048486!GO:0042770;DNA damage response, signal transduction;0.00634021522109841!GO:0043596;nuclear replication fork;0.00641410583967007!GO:0006505;GPI anchor metabolic process;0.00686563819994808!GO:0046467;membrane lipid biosynthetic process;0.00705821169638612!GO:0005853;eukaryotic translation elongation factor 1 complex;0.00710289868817128!GO:0000123;histone acetyltransferase complex;0.00718003342530418!GO:0043189;H4/H2A histone acetyltransferase complex;0.00718003342530418!GO:0000209;protein polyubiquitination;0.00718003342530418!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00718003342530418!GO:0030663;COPI coated vesicle membrane;0.0072498124072019!GO:0030126;COPI vesicle coat;0.0072498124072019!GO:0008139;nuclear localization sequence binding;0.00725774058747146!GO:0016859;cis-trans isomerase activity;0.00741455835296872!GO:0008022;protein C-terminus binding;0.00752808108430588!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.00763101610740028!GO:0030133;transport vesicle;0.00764922640650557!GO:0019318;hexose metabolic process;0.0077421839077453!GO:0044452;nucleolar part;0.00779809402385305!GO:0006626;protein targeting to mitochondrion;0.00784093567029612!GO:0006891;intra-Golgi vesicle-mediated transport;0.00784093567029612!GO:0005774;vacuolar membrane;0.00786022698564814!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00801540348922076!GO:0008610;lipid biosynthetic process;0.0084696912483464!GO:0032561;guanyl ribonucleotide binding;0.00856600731632283!GO:0019001;guanyl nucleotide binding;0.00856600731632283!GO:0004532;exoribonuclease activity;0.00860526632952157!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00860526632952157!GO:0030118;clathrin coat;0.00872446910467082!GO:0032259;methylation;0.00872446910467082!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.00873757578389687!GO:0010468;regulation of gene expression;0.00874037884884494!GO:0005669;transcription factor TFIID complex;0.008781322101935!GO:0016044;membrane organization and biogenesis;0.00885098440542498!GO:0005996;monosaccharide metabolic process;0.00887613511095375!GO:0000030;mannosyltransferase activity;0.00888420250566276!GO:0006310;DNA recombination;0.00890700130182225!GO:0008361;regulation of cell size;0.00911703298770403!GO:0031124;mRNA 3'-end processing;0.00991494670352138!GO:0006082;organic acid metabolic process;0.00998182648009141!GO:0016272;prefoldin complex;0.0100759476085609!GO:0000049;tRNA binding;0.0101821575776168!GO:0031570;DNA integrity checkpoint;0.010378040053287!GO:0007052;mitotic spindle organization and biogenesis;0.0107601195980788!GO:0016049;cell growth;0.0108058912755097!GO:0031072;heat shock protein binding;0.0109598492789266!GO:0008632;apoptotic program;0.0109898208387936!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0112202748218502!GO:0019752;carboxylic acid metabolic process;0.0113324167886598!GO:0047485;protein N-terminus binding;0.0114106955960634!GO:0008637;apoptotic mitochondrial changes;0.0114164984992687!GO:0030659;cytoplasmic vesicle membrane;0.0114975781409134!GO:0015631;tubulin binding;0.0116009208878022!GO:0007050;cell cycle arrest;0.0118367319191089!GO:0005869;dynactin complex;0.0127723420252209!GO:0000781;chromosome, telomeric region;0.0130003062068993!GO:0004860;protein kinase inhibitor activity;0.0130003062068993!GO:0005832;chaperonin-containing T-complex;0.0130407749265724!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.013317856071684!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.0133504736045044!GO:0019843;rRNA binding;0.0134310569568579!GO:0004003;ATP-dependent DNA helicase activity;0.0135752627701816!GO:0050662;coenzyme binding;0.0135932306744998!GO:0035267;NuA4 histone acetyltransferase complex;0.0140398988603655!GO:0006769;nicotinamide metabolic process;0.0141363553929809!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0142187104375679!GO:0040029;regulation of gene expression, epigenetic;0.0144502507889004!GO:0045045;secretory pathway;0.0146707040361656!GO:0006497;protein amino acid lipidation;0.01470773503371!GO:0005791;rough endoplasmic reticulum;0.0149411710633467!GO:0008601;protein phosphatase type 2A regulator activity;0.0155054432491219!GO:0005874;microtubule;0.0155140781637316!GO:0018196;peptidyl-asparagine modification;0.0155456849661149!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0155456849661149!GO:0000082;G1/S transition of mitotic cell cycle;0.0158462648477431!GO:0048500;signal recognition particle;0.0158462648477431!GO:0006767;water-soluble vitamin metabolic process;0.0160103492762634!GO:0044437;vacuolar part;0.0162190536573341!GO:0006509;membrane protein ectodomain proteolysis;0.0164071507106892!GO:0033619;membrane protein proteolysis;0.0164071507106892!GO:0044433;cytoplasmic vesicle part;0.0169160374725326!GO:0000776;kinetochore;0.017040841745514!GO:0007093;mitotic cell cycle checkpoint;0.0176348428229529!GO:0043022;ribosome binding;0.017673720543101!GO:0030658;transport vesicle membrane;0.0177337224006901!GO:0007040;lysosome organization and biogenesis;0.0178120088041359!GO:0006740;NADPH regeneration;0.0178561117659303!GO:0006098;pentose-phosphate shunt;0.0178561117659303!GO:0040008;regulation of growth;0.0184833984671405!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0188054341725078!GO:0032774;RNA biosynthetic process;0.0194582439571841!GO:0046966;thyroid hormone receptor binding;0.0198893201912911!GO:0007346;regulation of progression through mitotic cell cycle;0.0200821591501399!GO:0016251;general RNA polymerase II transcription factor activity;0.0204083009655844!GO:0045792;negative regulation of cell size;0.0206109737176859!GO:0006338;chromatin remodeling;0.0206200445468446!GO:0051052;regulation of DNA metabolic process;0.0206934722129028!GO:0009303;rRNA transcription;0.0214169662987727!GO:0030119;AP-type membrane coat adaptor complex;0.0215028720865546!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0217613082422982!GO:0006351;transcription, DNA-dependent;0.0219572207637871!GO:0008312;7S RNA binding;0.0228368981861811!GO:0031123;RNA 3'-end processing;0.0230277733655345!GO:0006275;regulation of DNA replication;0.0232136568798624!GO:0000077;DNA damage checkpoint;0.0232939815533082!GO:0046426;negative regulation of JAK-STAT cascade;0.0233174669390844!GO:0005777;peroxisome;0.0233964379566394!GO:0042579;microbody;0.0233964379566394!GO:0030132;clathrin coat of coated pit;0.0242139642076171!GO:0008180;signalosome;0.0246049684609288!GO:0000086;G2/M transition of mitotic cell cycle;0.0258068196361365!GO:0008276;protein methyltransferase activity;0.0260298353656239!GO:0032039;integrator complex;0.0263410714770422!GO:0000096;sulfur amino acid metabolic process;0.0264765263468224!GO:0008538;proteasome activator activity;0.0271185283320913!GO:0007021;tubulin folding;0.0271296794259152!GO:0001836;release of cytochrome c from mitochondria;0.0271384977539764!GO:0009112;nucleobase metabolic process;0.0272312967037921!GO:0030308;negative regulation of cell growth;0.0272629410439616!GO:0008408;3'-5' exonuclease activity;0.0275238597891456!GO:0045892;negative regulation of transcription, DNA-dependent;0.0286208815522759!GO:0007033;vacuole organization and biogenesis;0.0288896419842074!GO:0030131;clathrin adaptor complex;0.0296393217785533!GO:0031902;late endosome membrane;0.0298518846708057!GO:0016584;nucleosome positioning;0.0299788589247222!GO:0008286;insulin receptor signaling pathway;0.0300567260940752!GO:0043601;nuclear replisome;0.0306139427894616!GO:0030894;replisome;0.0306139427894616!GO:0019362;pyridine nucleotide metabolic process;0.0306828032468481!GO:0032200;telomere organization and biogenesis;0.0310074581920712!GO:0000723;telomere maintenance;0.0310074581920712!GO:0003677;DNA binding;0.0311643167421318!GO:0006144;purine base metabolic process;0.0314898732325972!GO:0051540;metal cluster binding;0.0320698896207258!GO:0051536;iron-sulfur cluster binding;0.0320698896207258!GO:0005784;translocon complex;0.0321788796464843!GO:0050178;phenylpyruvate tautomerase activity;0.0323817036051555!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0324841386246527!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0327780812110244!GO:0045047;protein targeting to ER;0.0327780812110244!GO:0019887;protein kinase regulator activity;0.0329652959465227!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0330409172208008!GO:0009304;tRNA transcription;0.0335258699558941!GO:0006778;porphyrin metabolic process;0.0335258699558941!GO:0033013;tetrapyrrole metabolic process;0.0335258699558941!GO:0006378;mRNA polyadenylation;0.0338614156741905!GO:0004536;deoxyribonuclease activity;0.0341052691747056!GO:0000175;3'-5'-exoribonuclease activity;0.0341055368624154!GO:0042158;lipoprotein biosynthetic process;0.034145631404567!GO:0044454;nuclear chromosome part;0.034145631404567!GO:0000287;magnesium ion binding;0.034145631404567!GO:0042987;amyloid precursor protein catabolic process;0.0342916946615869!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0353230962781244!GO:0051287;NAD binding;0.0355285408587735!GO:0004549;tRNA-specific ribonuclease activity;0.0355285408587735!GO:0051539;4 iron, 4 sulfur cluster binding;0.0357707600168703!GO:0007059;chromosome segregation;0.0359292845097035!GO:0048037;cofactor binding;0.0362612715719956!GO:0030660;Golgi-associated vesicle membrane;0.0363313239283796!GO:0003887;DNA-directed DNA polymerase activity;0.0363313239283796!GO:0006066;alcohol metabolic process;0.0369357198708419!GO:0030149;sphingolipid catabolic process;0.0369357198708419!GO:0030518;steroid hormone receptor signaling pathway;0.0370335891913678!GO:0000163;protein phosphatase type 1 activity;0.0370719738436352!GO:0006376;mRNA splice site selection;0.0375450379037532!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0375450379037532!GO:0000922;spindle pole;0.0375450379037532!GO:0006308;DNA catabolic process;0.0376751026281521!GO:0012506;vesicle membrane;0.0377767780463306!GO:0004448;isocitrate dehydrogenase activity;0.0377767780463306!GO:0031371;ubiquitin conjugating enzyme complex;0.0379941440701104!GO:0006354;RNA elongation;0.0382413074333569!GO:0000792;heterochromatin;0.0382944921030446!GO:0045941;positive regulation of transcription;0.0384260996552253!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0385281242602463!GO:0030911;TPR domain binding;0.0385737075200774!GO:0017166;vinculin binding;0.0385737075200774!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.03866659482003!GO:0016791;phosphoric monoester hydrolase activity;0.0393125858668179!GO:0006406;mRNA export from nucleus;0.0399748682466356!GO:0000178;exosome (RNase complex);0.0400986644869396!GO:0019207;kinase regulator activity;0.0412599994551327!GO:0000228;nuclear chromosome;0.0412599994551327!GO:0045936;negative regulation of phosphate metabolic process;0.0414211737684696!GO:0004523;ribonuclease H activity;0.0421416738431798!GO:0000118;histone deacetylase complex;0.0425613020919062!GO:0031628;opioid receptor binding;0.0429080156424587!GO:0031852;mu-type opioid receptor binding;0.0429080156424587!GO:0045449;regulation of transcription;0.0432081302283184!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.044340789636869!GO:0007017;microtubule-based process;0.0443555049086086!GO:0050790;regulation of catalytic activity;0.0447017862801722!GO:0019210;kinase inhibitor activity;0.0450397403328427!GO:0051059;NF-kappaB binding;0.0454027994754468!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0462369494814855!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0462369494814855!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0462369494814855!GO:0045926;negative regulation of growth;0.046562971232816!GO:0030134;ER to Golgi transport vesicle;0.0466043999933162!GO:0006367;transcription initiation from RNA polymerase II promoter;0.046659621392568!GO:0005876;spindle microtubule;0.047862357527963!GO:0016717;oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water;0.0482095357234877!GO:0005765;lysosomal membrane;0.0482529732918464!GO:0006779;porphyrin biosynthetic process;0.048810260820332!GO:0033014;tetrapyrrole biosynthetic process;0.048810260820332!GO:0000159;protein phosphatase type 2A complex;0.0490721397124751!GO:0004526;ribonuclease P activity;0.0498922011651672 | |||
|sample_id=13163 | |||
|sample_note= | |||
|sample_sex=female | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=breast | |||
|time=00hr00min | |||
|timecourse=MCF7_response_to_EGF,MCF7_response_to_HRG | |||
|top_motifs=NFY{A,B,C}:2.25627711736;MYOD1:2.14072059027;PBX1:1.98358019162;SNAI1..3:1.89468129673;ZEB1:1.72219074815;POU2F1..3:1.56265137745;XCPE1{core}:1.34864081479;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.30853148682;LMO2:1.30076945423;NANOG:1.28723314418;FOX{F1,F2,J1}:1.21923899467;HOXA9_MEIS1:1.1372669432;ONECUT1,2:1.12573322782;ELK1,4_GABP{A,B1}:1.07653592829;SP1:1.07596191218;LHX3,4:1.03002307607;LEF1_TCF7_TCF7L1,2:1.00157457187;NRF1:0.961322472094;GFI1:0.907467066402;FOXQ1:0.869146722524;PPARG:0.865085648742;STAT1,3:0.859104053448;IKZF1:0.84021936096;YY1:0.776304411583;bHLH_family:0.753338968573;SOX{8,9,10}:0.736927122429;E2F1..5:0.699847785487;TFDP1:0.694964954067;ESRRA:0.67560895559;NR5A1,2:0.657125552338;EGR1..3:0.601313998393;MYB:0.579779500539;TFAP2{A,C}:0.574872349029;ARID5B:0.560331890908;VSX1,2:0.536195553556;HAND1,2:0.436538693583;MED-1{core}:0.398828443912;HIF1A:0.380754163689;ZNF143:0.360842970941;ESR1:0.354999511246;BREu{core}:0.324113491037;FOXN1:0.297854956844;FOXL1:0.280051660903;HOX{A5,B5}:0.267139520849;ZNF148:0.250189079367;RFX1:0.23425393054;HES1:0.229089021794;TBP:0.21421218785;ATF2:0.198637096705;SREBF1,2:0.183228842536;FOX{D1,D2}:0.181056250037;FOXA2:0.164740890584;AR:0.162586655239;RFX2..5_RFXANK_RFXAP:0.160980638536;PAX2:0.15106803048;TP53:0.147383214099;HNF1A:0.136883579147;TFCP2:0.131861205983;RXRA_VDR{dimer}:0.123872239685;ALX1:0.113458618355;HOX{A6,A7,B6,B7}:0.102247856619;OCT4_SOX2{dimer}:0.0925725928739;TEAD1:0.0698896580294;ZNF423:0.067993929674;FOS_FOS{B,L1}_JUN{B,D}:0.0629150425999;PAX1,9:0.0529902499473;NFIL3:0.049739800162;CDX1,2,4:0.030449274606;PAX5:0.0138166863193;EBF1:0.0118063007653;ATF6:0.00528317216995;REST:-0.00804614294254;TBX4,5:-0.0177934833139;TFAP4:-0.0249532903503;STAT5{A,B}:-0.0276934445581;HMX1:-0.0546053637455;HNF4A_NR2F1,2:-0.0584751345792;MTF1:-0.0592103520519;ADNP_IRX_SIX_ZHX:-0.10440617948;RBPJ:-0.111529427015;TLX2:-0.120102550147;FOSL2:-0.122511860407;GTF2A1,2:-0.136585738248;NFE2L2:-0.145945169392;TFAP2B:-0.148772564339;NKX2-3_NKX2-5:-0.157734178034;HIC1:-0.16018389766;FOX{I1,J2}:-0.182563280273;TLX1..3_NFIC{dimer}:-0.19380300743;NFE2:-0.201761415177;NKX6-1,2:-0.209462971053;ELF1,2,4:-0.215331039124;TOPORS:-0.221284628532;CDC5L:-0.23153120477;BACH2:-0.233319650962;RORA:-0.264843761674;MEF2{A,B,C,D}:-0.268782740119;SOX5:-0.285733472361;GATA6:-0.306244411967;ATF5_CREB3:-0.307201108574;PITX1..3:-0.311315586632;NR1H4:-0.322757623455;MAFB:-0.323856509016;POU1F1:-0.327316518356;GZF1:-0.335082685566;RREB1:-0.339306039393;JUN:-0.339311831708;NFKB1_REL_RELA:-0.34797048762;ZIC1..3:-0.358258202671;CREB1:-0.379565746328;ZFP161:-0.381595407219;UFEwm:-0.408345008162;GTF2I:-0.445620177602;SOX2:-0.482028321891;SPIB:-0.483555938581;DBP:-0.496659093201;POU6F1:-0.538596815392;PAX6:-0.539710199223;ZBTB6:-0.554204503847;EN1,2:-0.560794932804;HLF:-0.574167623685;CRX:-0.575584921224;FOXM1:-0.58024003119;NFE2L1:-0.587358299212;ATF4:-0.590104559301;ZNF384:-0.597812956207;EVI1:-0.610521307659;HSF1,2:-0.614562036533;PATZ1:-0.623232250926;TAL1_TCF{3,4,12}:-0.627439609955;RUNX1..3:-0.629228294285;EP300:-0.647388024374;CUX2:-0.657115506487;NHLH1,2:-0.66521860006;POU3F1..4:-0.672388414882;GFI1B:-0.699688133564;MYFfamily:-0.717324221794;ALX4:-0.736379886677;MTE{core}:-0.741008132835;MAZ:-0.742684469383;ETS1,2:-0.769352286865;TGIF1:-0.770999241065;SRF:-0.786996288703;CEBPA,B_DDIT3:-0.795134687266;SPI1:-0.799220572592;PRRX1,2:-0.801629400171;HOX{A4,D4}:-0.803032000513;NKX3-2:-0.820637205819;ZBTB16:-0.824680135223;PAX4:-0.841747891563;STAT2,4,6:-0.848270144368;NKX2-2,8:-0.858985851512;IRF7:-0.866750830644;FOXP3:-0.866767011504;SOX17:-0.869047048701;NANOG{mouse}:-0.872924588026;IKZF2:-0.886704765955;PDX1:-0.908743006738;PAX3,7:-0.946822983692;NR6A1:-0.983454356868;NFATC1..3:-0.988239863411;PAX8:-0.990648934975;TEF:-0.991859867946;IRF1,2:-1.01944958338;FOXO1,3,4:-1.03289489013;FOXD3:-1.0390539938;DMAP1_NCOR{1,2}_SMARC:-1.04848482827;POU5F1:-1.07476198088;AHR_ARNT_ARNT2:-1.07501884586;SMAD1..7,9:-1.09390747416;BPTF:-1.16947365915;NFIX:-1.21823540999;KLF4:-1.29083374087;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.29384477053;ZNF238:-1.30080351645;HBP1_HMGB_SSRP1_UBTF:-1.30443146511;MZF1:-1.31596478553;NKX3-1:-1.31910043876;XBP1:-1.32068711976;NR3C1:-1.40690961063;GATA4:-1.42756941019;AIRE:-1.46161344386;FOXP1:-1.48877261445;GLI1..3:-1.49849720303;SPZ1:-1.65004159502;MYBL2:-1.70370166447;NKX2-1,4:-1.70457238461;GCM1,2:-1.72530339812;PRDM1:-1.77494354179;T:-1.90182248766;RXR{A,B,G}:-2.01157683768;HMGA1,2:-2.08905435235 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:13163-141B4;search_select_hide=table117:FF:13163-141B4 | |||
}} | }} |
Latest revision as of 18:52, 4 June 2020
Name: | MCF7 breast cancer cell line response to EGF1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs12703 |
Sample type: | time courses |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12703
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12703
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.132 |
10 | 10 | 0.545 |
100 | 100 | 0.668 |
101 | 101 | 0.09 |
102 | 102 | 0.263 |
103 | 103 | 0.102 |
104 | 104 | 0.933 |
105 | 105 | 0.346 |
106 | 106 | 0.0153 |
107 | 107 | 0.0313 |
108 | 108 | 0.833 |
109 | 109 | 0.0507 |
11 | 11 | 0.441 |
110 | 110 | 0.688 |
111 | 111 | 0.0163 |
112 | 112 | 0.2 |
113 | 113 | 0.0976 |
114 | 114 | 0.0445 |
115 | 115 | 0.146 |
116 | 116 | 0.338 |
117 | 117 | 0.423 |
118 | 118 | 0.605 |
119 | 119 | 0.38 |
12 | 12 | 0.482 |
120 | 120 | 0.569 |
121 | 121 | 0.891 |
122 | 122 | 0.169 |
123 | 123 | 0.0115 |
124 | 124 | 0.34 |
125 | 125 | 0.345 |
126 | 126 | 0.815 |
127 | 127 | 0.69 |
128 | 128 | 0.0159 |
129 | 129 | 0.945 |
13 | 13 | 0.494 |
130 | 130 | 0.00576 |
131 | 131 | 0.221 |
132 | 132 | 0.511 |
133 | 133 | 0.00803 |
134 | 134 | 0.0719 |
135 | 135 | 0.356 |
136 | 136 | 0.00139 |
137 | 137 | 0.0976 |
138 | 138 | 0.15 |
139 | 139 | 0.133 |
14 | 14 | 0.875 |
140 | 140 | 0.0583 |
141 | 141 | 0.834 |
142 | 142 | 0.253 |
143 | 143 | 0.0932 |
144 | 144 | 0.413 |
145 | 145 | 0.163 |
146 | 146 | 0.57 |
147 | 147 | 0.906 |
148 | 148 | 0.0013 |
149 | 149 | 0.158 |
15 | 15 | 0.369 |
150 | 150 | 0.79 |
151 | 151 | 0.0488 |
152 | 152 | 0.524 |
153 | 153 | 0.105 |
154 | 154 | 0.195 |
155 | 155 | 0.0804 |
156 | 156 | 0.899 |
157 | 157 | 0.271 |
158 | 158 | 0.292 |
159 | 159 | 0.885 |
16 | 16 | 0.482 |
160 | 160 | 0.805 |
161 | 161 | 0.611 |
162 | 162 | 0.943 |
163 | 163 | 0.707 |
164 | 164 | 0.426 |
165 | 165 | 0.178 |
166 | 166 | 0.0752 |
167 | 167 | 0.605 |
168 | 168 | 0.25 |
169 | 169 | 0.701 |
17 | 17 | 0.655 |
18 | 18 | 0.0802 |
19 | 19 | 0.312 |
2 | 2 | 0.553 |
20 | 20 | 0.392 |
21 | 21 | 0.217 |
22 | 22 | 0.598 |
23 | 23 | 0.00221 |
24 | 24 | 0.976 |
25 | 25 | 0.802 |
26 | 26 | 0.438 |
27 | 27 | 0.689 |
28 | 28 | 0.911 |
29 | 29 | 0.714 |
3 | 3 | 0.0659 |
30 | 30 | 0.412 |
31 | 31 | 0.524 |
32 | 32 | 0.091 |
33 | 33 | 0.3 |
34 | 34 | 0.274 |
35 | 35 | 0.0343 |
36 | 36 | 0.394 |
37 | 37 | 0.17 |
38 | 38 | 0.933 |
39 | 39 | 0.333 |
4 | 4 | 0.379 |
40 | 40 | 0.257 |
41 | 41 | 0.22 |
42 | 42 | 0.301 |
43 | 43 | 0.0841 |
44 | 44 | 0.283 |
45 | 45 | 0.766 |
46 | 46 | 0.169 |
47 | 47 | 0.667 |
48 | 48 | 0.974 |
49 | 49 | 0.128 |
5 | 5 | 0.178 |
50 | 50 | 0.515 |
51 | 51 | 0.76 |
52 | 52 | 0.318 |
53 | 53 | 0.112 |
54 | 54 | 0.582 |
55 | 55 | 0.409 |
56 | 56 | 0.701 |
57 | 57 | 0.306 |
58 | 58 | 0.405 |
59 | 59 | 0.539 |
6 | 6 | 0.716 |
60 | 60 | 0.0461 |
61 | 61 | 0.548 |
62 | 62 | 0.142 |
63 | 63 | 0.204 |
64 | 64 | 0.807 |
65 | 65 | 0.158 |
66 | 66 | 0.00301 |
67 | 67 | 0.495 |
68 | 68 | 0.737 |
69 | 69 | 0.327 |
7 | 7 | 0.939 |
70 | 70 | 0.0908 |
71 | 71 | 0.414 |
72 | 72 | 0.519 |
73 | 73 | 0.98 |
74 | 74 | 0.0223 |
75 | 75 | 0.823 |
76 | 76 | 0.69 |
77 | 77 | 0.215 |
78 | 78 | 0.96 |
79 | 79 | 0.262 |
8 | 8 | 0.471 |
80 | 80 | 0.0681 |
81 | 81 | 0.111 |
82 | 82 | 0.287 |
83 | 83 | 0.167 |
84 | 84 | 0.654 |
85 | 85 | 0.0712 |
86 | 86 | 0.572 |
87 | 87 | 0.00198 |
88 | 88 | 0.975 |
89 | 89 | 0.0863 |
9 | 9 | 0.181 |
90 | 90 | 1.81959e-5 |
91 | 91 | 0.0698 |
92 | 92 | 0.0433 |
93 | 93 | 0.578 |
94 | 94 | 0.122 |
95 | 95 | 0.0157 |
96 | 96 | 0.171 |
97 | 97 | 0.898 |
98 | 98 | 0.411 |
99 | 99 | 0.956 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12703
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000426 human MCF7 breast cancer cell line 0min after EGF1 treatment sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
7 (disease of anatomical entity)
5093 (thoracic cancer)
305 (carcinoma)
299 (adenocarcinoma)
1612 (breast cancer)
UBERON: Anatomy
0000468 (multi-cellular organism)
0000310 (breast)
0002100 (trunk)
0000475 (organism subdivision)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0001062 (anatomical entity)
0009569 (subdivision of trunk)
0001443 (chest)
0000915 (thoracic segment of trunk)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0000350 (experimentally modified sample)
0000344 (0 minute sample)
0000330 (EGF1 treatment sample)
0100093 (MCF-7 cell sample)
0100297 (carcinoma cell line sample)
0101912 (breast adenocarcinoma cell line sample)
0101120 (epithelial cell line sample)
0100816 (breast cell line sample)
0100167 (adenocarcinoma cell line sample)
0100356 (breast cancer cell line sample)
0000426 (human MCF7 breast cancer cell line 0min after EGF1 treatment sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
NA