FF:11867-125B4: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005251 | ||
| | |accession_numbers=CAGE;DRX008144;DRR009016;DRZ000441;DRZ001826;DRZ011791;DRZ013176 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000766,CL:0000219,CL:0000325,CL:0000473,CL:0000234,CL:0000738,CL:0002087,CL:0000255,CL:0000576,CL:0000860,CL:0002057 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000625,FF:0000350,FF:0000634,FF:0011105 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr11:47400078..47400106,-!p1@SPI1!2.80!629.67!SPI1;;chr2:68592406..68592424,+!p1@PLEK!2.80!624.96!PLEK;;chr12:54778471..54778528,-!p1@ZNF385A!2.55!356.53!ZNF385A;;chr7:115670804..115670825,-!p1@TFEC!2.27!187.30!TFEC;;chr11:47399947..47399961,-!p3@SPI1!2.12!130.45!SPI1;;chr2:70142232..70142251,+!p1@MXD1!2.09!651.69!MXD1;;chr11:47400062..47400077,-!p2@SPI1!2.05!112.00!SPI1;;chr20:39317868..39317884,-!p1@MAFB!1.97!1024.04!MAFB;;chr1:25256756..25256774,-!p1@RUNX3!1.95!161.51!RUNX3;;chr11:47399996..47400014,-!p4@SPI1!1.90!77.74!SPI1;;chr16:85932760..85932775,+!p1@IRF8!1.87!73.98!IRF8;;chr10:64576105..64576133,-!p1@EGR2!1.85!137.98!EGR2;;chr10:35484053..35484076,+!p1@CREM!1.84!163.58!CREM;;chr11:47400032..47400043,-!p5@SPI1!1.84!68.90!SPI1;;chr21:34442439..34442455,+!p1@OLIG1!1.84!68.90!OLIG1;;chr19:50432132..50432217,+!p2@ATF5!1.80!73.79!ATF5;;chr6:106534192..106534224,+!p1@PRDM1!1.79!166.03!PRDM1;;chr14:35872453..35872485,-!p2@NFKBIA!1.75!132.33!NFKBIA;;chr12:54778351..54778378,-!p6@ZNF385A!1.72!51.39!ZNF385A;;chr19:45971246..45971265,+!p1@FOSB!1.71!872.50!FOSB;;chr2:145277640..145277771,-!p1@ZEB2!1.71!632.49!ZEB2;;chr10:31288398..31288455,-!p2@ZNF438!1.69!54.97!ZNF438;;chr12:72056800..72056834,+!p1@THAP2!1.68!62.12!THAP2;;chr10:31288370..31288393,-!p3@ZNF438!1.60!38.59!ZNF438;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.57!35.95!ZBED1;;chr2:157189180..157189290,-!p1@NR4A2!1.55!170.92!NR4A2;;chr6:106534230..106534254,+!p2@PRDM1!1.54!81.51!PRDM1;;chr11:47400045..47400060,-!p6@SPI1!1.53!32.94!SPI1;;chr2:145275162..145275202,-!p2@ZEB2!1.52!183.72!ZEB2;;chr9:102584262..102584276,+!p1@NR4A3!1.51!68.33!NR4A3;;chr6:44233252..44233296,-!p1@NFKBIE!1.50!288.39!NFKBIE;;chr10:51572408..51572454,+!p3@NCOA4!1.50!172.99!NCOA4;;chr20:48599506..48599526,+!p1@SNAI1!1.48!181.84!SNAI1;;chr7:128577972..128578047,+!p1@IRF5!1.46!43.30!IRF5;;chr14:35873947..35873965,-!p1@NFKBIA!1.45!1657.29!NFKBIA;;chr7:50344289..50344323,+!p1@IKZF1!1.45!27.30!IKZF1;;chr10:51572339..51572376,+!p4@NCOA4!1.44!58.92!NCOA4;;chr12:72056749..72056767,+!p6@THAP2!1.44!29.37!THAP2;;chr19:45252008..45252024,+!p2@BCL3!1.43!83.58!BCL3;;chr9:102584159..102584174,+!p2@NR4A3!1.43!45.93!NR4A3;;chr21:36260295..36260310,-!p3@RUNX1!1.43!40.85!RUNX1;;chr16:31885093..31885165,+!p1@ZNF267!1.42!374.98!ZNF267;;chr12:52445218..52445237,+!p1@NR4A1!1.42!306.65!NR4A1;;chr13:41593425..41593480,-!p1@ELF1!1.40!149.65!ELF1;;chr12:72056773..72056796,+!p3@THAP2!1.39!30.31!THAP2;;chr6:144385698..144385742,-!p2@PLAGL1!1.39!28.80!PLAGL1;;chrX:129244454..129244488,-!p1@ELF4!1.38!159.25!ELF4;;chr11:47399920..47399931,-!p7@SPI1!1.37!22.21!SPI1;;chr14:35872962..35873025,-!p3@NFKBIA!1.36!54.40!NFKBIA;;chr2:145277882..145277967,-!p3@ZEB2!1.35!36.71!ZEB2;;chr2:70167296..70167306,+!p3@MXD1!1.35!32.38!MXD1;;chr12:48298765..48298783,-!p2@VDR!1.33!41.60!VDR;;chr20:48807351..48807384,+!p1@CEBPB!1.32!1964.50!CEBPB;;chr19:36391434..36391450,-!p1@NFKBID!1.32!38.21!NFKBID;;chr9:102584128..102584144,+!p3@NR4A3!1.32!37.65!NR4A3;;chr19:13213662..13213686,-!p1@LYL1!1.31!28.24!LYL1;;chr18:3449720..3449749,+!p2@TGIF1!1.30!39.91!TGIF1;;chr2:70314240..70314256,+!p4@PCBP1!1.30!38.59!PCBP1;;chr2:28618532..28618610,+!p4@FOSL2!1.30!31.81!FOSL2;;chr2:61108695..61108753,+!p1@REL!1.29!124.62!REL;;chr10:104155480..104155534,+!p2@NFKB2!1.29!116.90!NFKB2;;chr19:45250948..45250998,+!p3@BCL3!1.29!46.31!BCL3;;chr10:104155659..104155676,+!p4@NFKB2!1.29!22.78!NFKB2;;chr2:68592394..68592405,+!p2@PLEK!1.28!18.26!PLEK;;chr10:104154246..104154347,+!p3@NFKB2!1.27!106.73!NFKB2;;chr8:22550982..22550999,-!p1@EGR3!1.27!49.51!EGR3;;chr17:38497662..38497713,+!p4@RARA!1.27!20.52!RARA;;chr1:25256439..25256476,-!p3@RUNX3!1.27!17.51!RUNX3;;chr12:48298785..48298828,-!p1@VDR!1.26!89.23!VDR;;chr1:212782094..212782109,+!p1@ATF3!1.25!447.64!ATF3;;chr9:117150254..117150271,-!p1@AKNA!1.24!43.86!AKNA;;chr19:45251395..45251432,+!p8@BCL3!1.24!16.38!BCL3;;chr4:106068026..106068084,+!p1@TET2!1.23!141.37!TET2;;chr1:156470515..156470542,-!p2@MEF2D!1.23!81.89!MEF2D;;chr6:15246200..15246214,+!p2@JARID2!1.23!43.67!JARID2;;chr10:35484090..35484104,+!p6@CREM!1.23!15.81!CREM;;chr21:30671690..30671762,+!p2@BACH1!1.22!52.14!BACH1;;chr20:48807615..48807644,+!p6@CEBPB!1.22!25.79!CEBPB;;chr2:28615716..28615733,+!p1@FOSL2!1.21!705.34!FOSL2;;chr21:30671235..30671253,+!p1@BACH1!1.21!191.07!BACH1;;chr1:37940170..37940190,+!p1@ZC3H12A!1.21!182.41!ZC3H12A;;chrX:129244430..129244442,-!p5@ELF4!1.21!15.25!ELF4;;chr1:157108130..157108173,-!p1@ETV3!1.20!106.17!ETV3;;chr4:103422499..103422632,+!p1@NFKB1!1.19!295.54!NFKB1;;chr12:11802753..11802834,+!p2@ETV6!1.18!69.27!ETV6;;chr6:391743..391759,+!p1@IRF4!1.18!14.31!IRF4;;chr2:97202480..97202499,+!p1@ARID5A!1.17!137.04!ARID5A;;chr12:96588219..96588263,+!p2@ELK3!1.17!98.07!ELK3;;chr12:96588279..96588299,+!p4@ELK3!1.17!64.57!ELK3;;chrX:153305787..153305807,-!p3@MECP2!1.17!13.93!MECP2;;chr21:36421535..36421610,-!p2@RUNX1!1.16!47.44!RUNX1;;chr19:19496539..19496576,+!p8@GATAD2A!1.16!23.53!GATAD2A;;chr18:3449618..3449634,+!p13@TGIF1!1.16!16.75!TGIF1;;chr7:115670792..115670797,-!p2@TFEC!1.16!13.55!TFEC;;chr2:238600998..238601013,+!p5@LRRFIP1!1.16!13.37!LRRFIP1;;chr2:238600933..238600985,+!p3@LRRFIP1!1.15!71.53!LRRFIP1;;chr14:35872926..35872951,-!p4@NFKBIA!1.15!18.45!NFKBIA;;chr21:34398234..34398250,+!p1@OLIG2!1.15!13.18!OLIG2;;chr14:35872494..35872511,-!p5@NFKBIA!1.14!17.13!NFKBIA;;chr19:45254529..45254561,+!p10@BCL3!1.13!16.94!BCL3;;chr14:35872414..35872425,-!p7@NFKBIA!1.13!13.93!NFKBIA;;chr19:45251943..45252006,+!p1@BCL3!1.12!316.44!BCL3;;chr3:12329397..12329433,+!p2@PPARG!1.12!27.67!PPARG;;chr4:81104895..81104920,+!p2@PRDM8!1.12!18.45!PRDM8;;chr1:156470494..156470505,-!p3@MEF2D!1.12!17.69!MEF2D;;chr6:106535598..106535637,+!p7@PRDM1!1.12!12.24!PRDM1;;chr10:64018918..64018936,+!p2@ZNF365!1.11!11.86!ZNF365;;chr19:50432104..50432126,+!p6@ATF5!1.10!11.67!ATF5;;chr11:65430554..65430579,-!p3@RELA!1.09!28.80!RELA;;chr18:3449527..3449582,+!p6@TGIF1!1.09!21.46!TGIF1;;chr9:102584241..102584261,+!p4@NR4A3!1.09!17.51!NR4A3;;chr12:54694758..54694805,-!p1@NFE2!1.09!13.55!NFE2;;chr3:12330560..12330579,+!p1@PPARG!1.09!12.99!PPARG;;chr19:33793430..33793447,-!p1@CEBPA!1.08!46.87!CEBPA;;chr12:54785074..54785122,-!p2@ZNF385A!1.08!16.94!ZNF385A;;chr10:31288329..31288353,-!p7@ZNF438!1.08!11.11!ZNF438;;chr19:54058073..54058088,+!p1@ZNF331!1.08!11.11!ZNF331;;chr7:137620684..137620711,-!p4@CREB3L2!1.08!10.92!CREB3L2;;chr3:170075436..170075520,+!p1@SKIL!1.07!232.67!SKIL;;chr14:62162285..62162296,+!p3@HIF1A!1.07!56.47!HIF1A;;chr18:3449586..3449617,+!p8@TGIF1!1.07!17.51!TGIF1;;chr8:53373491..53373506,-!p4@ST18!1.07!10.73!ST18;;chr9:129567282..129567353,+!p1@ZBTB43!1.06!138.92!ZBTB43;;chr7:149470641..149470694,-!p1@ZNF467!1.06!48.00!ZNF467;;chr19:13213954..13214021,-!p4@LYL1!1.06!10.54!LYL1;;chr10:104155455..104155479,+!p1@NFKB2!1.05!150.59!NFKB2;;chr5:88178983..88179012,-!p1@MEF2C!1.05!80.00!MEF2C;;chr2:70142189..70142223,+!p2@MXD1!1.05!74.36!MXD1;;chr10:35484804..35484902,+!p2@CREM!1.05!39.53!CREM;;chr9:3525727..3525828,-!p2@RFX3!1.05!26.17!RFX3;;chr20:48807171..48807234,+!p4@CEBPB!1.05!22.59!CEBPB;;chr20:48807456..48807475,+!p3@CEBPB!1.05!19.95!CEBPB;;chr21:30672433..30672464,+!p6@BACH1!1.05!10.17!BACH1;;chr2:145277589..145277612,-!p12@ZEB2!1.05!10.17!ZEB2;;chr6:15246261..15246312,+!p1@JARID2!1.04!243.02!JARID2;;chr17:38498402..38498445,+!p3@RARA!1.04!36.52!RARA;;chr22:38597987..38598021,+!p2@MAFF!1.03!60.61!MAFF;;chr20:48807143..48807165,+!p11@CEBPB!1.03!14.68!CEBPB;;chr13:41593392..41593403,-!p7@ELF1!1.03!9.60!ELF1;;chr17:38474489..38474548,+!p1@RARA!1.02!304.39!RARA;;chr9:110252035..110252057,-!p1@KLF4!1.02!153.79!KLF4;;chr12:124873852..124873881,-!p3@NCOR2!1.02!57.79!NCOR2;;chr20:48807648..48807671,+!p9@CEBPB!1.02!13.93!CEBPB;;chr1:38325227..38325246,-!p2@MTF1!1.02!12.99!MTF1;;chr2:208394817..208394834,+!p3@CREB1!1.01!38.02!CREB1;;chr12:96588368..96588394,+!p3@ELK3!1.01!25.04!ELK3;;chr8:71316428..71316459,-!p2@NCOA2!1.01!15.81!NCOA2;;chr4:185395633..185395651,-!p2@IRF2!1.01!14.87!IRF2;;chr18:3449695..3449712,+!p9@TGIF1!1.01!14.49!TGIF1;;chr2:231090471..231090504,+!p2@SP140!1.01!9.22!SP140;;chr9:88969303..88969335,-!p1@ZCCHC6!1.00!86.03!ZCCHC6;;chr17:38498594..38498661,+!p2@RARA!1.00!30.50!RARA;;chr9:137217986..137218049,+!p3@RXRA!1.00!25.98!RXRA;;chr11:615942..615957,-!p1@IRF7!0.99!84.90!IRF7;;chr9:88969287..88969297,-!p3@ZCCHC6!0.99!12.05!ZCCHC6;;chr9:110250697..110250738,-!p2@KLF4!0.99!10.35!KLF4;;chr2:70166156..70166179,+!p4@MXD1!0.99!8.85!MXD1;;chr2:70166258..70166288,+!p5@MXD1!0.99!8.85!MXD1;;chr19:12902289..12902307,+!p1@JUNB!0.98!1987.09!JUNB;;chr8:116681123..116681143,-!p4@TRPS1!0.98!16.94!TRPS1;;chr2:185463247..185463263,+!p1@ZNF804A!0.98!15.44!ZNF804A;;chr2:145275228..145275241,-!p11@ZEB2!0.98!10.54!ZEB2;;chr2:145271342..145271377,-!p5@ZEB2!0.98!8.66!ZEB2;;chr21:34442540..34442560,+!p2@OLIG1!0.98!8.66!OLIG1;;chr3:39195037..39195069,-!p2@CSRNP1!0.97!53.46!CSRNP1;;chr7:17338324..17338341,+!p3@AHR!0.97!28.80!AHR;;chr14:35872542..35872553,-!p10@NFKBIA!0.97!8.28!NFKBIA;;chr7:17338266..17338282,+!p1@AHR!0.96!91.11!AHR;;chr19:45504688..45504782,+!p1@RELB!0.96!50.83!RELB;;chr18:3448455..3448480,+!p5@TGIF1!0.96!15.25!TGIF1;;chr2:231090433..231090469,+!p1@SP140!0.96!8.09!SP140;;chr21:36260343..36260402,-!p6@RUNX1!0.95!12.99!RUNX1;;chr19:45261992..45262010,+!p9@BCL3!0.95!11.29!BCL3;;chr12:54785054..54785072,-!p4@ZNF385A!0.95!9.04!ZNF385A;;chr19:45254508..45254528,+!p12@BCL3!0.95!8.66!BCL3;;chr14:75745523..75745537,+!p1@FOS!0.94!949.87!FOS;;chr7:150974206..150974255,-!p1@SMARCD3!0.94!50.07!SMARCD3;;chr19:6110474..6110551,-!p1@RFX2!0.94!49.13!RFX2;;chr19:19496624..19496660,+!p3@GATAD2A!0.94!36.14!GATAD2A;;chrX:106960180..106960197,-!p2@TSC22D3!0.94!30.50!TSC22D3;;chr14:62203595..62203676,+!p4@HIF1A!0.94!14.87!HIF1A;;chr2:231280954..231280965,+!p2@SP100!0.94!14.68!SP100;;chr14:62162258..62162269,+!p2@HIF1A!0.93!75.86!HIF1A;;chr19:42636586..42636607,-!p1@POU2F2!0.93!21.65!POU2F2;;chr15:90544532..90544563,+!p1@ZNF710!0.93!15.25!ZNF710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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000234;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000576;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000763;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000766;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000860;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002405 | |||
|ffid_belonging_in_development=CL:0000049,CL:0000134,CL:0002057 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment=FF:0000625,FF:0000634,FF:0011105,FF:11867-125B4 | |fonse_treatment=FF:0000625,FF:0000634,FF:0011105,FF:11867-125B4 | ||
|fonse_treatment_closure=FF:0000625,FF:0000634,FF:0011105,FF:11867-125B4 | |fonse_treatment_closure=FF:0000625,FF:0000634,FF:0011105,FF:11867-125B4 | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Cryptococcus%252c%2520donor1.CNhs13472.11867-125B4.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Cryptococcus%252c%2520donor1.CNhs13472.11867-125B4.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Cryptococcus%252c%2520donor1.CNhs13472.11867-125B4.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Cryptococcus%252c%2520donor1.CNhs13472.11867-125B4.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Cryptococcus%252c%2520donor1.CNhs13472.11867-125B4.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11867-125B4 | |||
|is_a=EFO:0002091;;FF:0011105 | |||
|is_obsolete= | |||
|library_id=CNhs13472 | |||
|library_id_phase_based=2:CNhs13472 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11867 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11867 | |||
|name=CD14+ monocytes - treated with Cryptococcus, donor1 | |||
|namespace= | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13472,LSID1024,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=125 | |||
|rna_catalog_number= | |||
|rna_concentration=0.83959 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=D3-8 | |||
|rna_od260/230=1.34 | |||
|rna_od260/280=2 | |||
|rna_position=B4 | |||
|rna_rin=9 | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=125B4 | |||
|rna_weight_ug=4.19795 | |||
|sample_age=69 | |||
|sample_category=primary cells | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=monocyte | |||
|sample_collaboration=Christine Wells (University of Queensland) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)=donor1 | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.35620307848797e-262!GO:0005737;cytoplasm;8.59179046685623e-130!GO:0043227;membrane-bound organelle;1.62981594284293e-123!GO:0043231;intracellular membrane-bound organelle;3.62670034388883e-123!GO:0043226;organelle;1.00179652560376e-114!GO:0043229;intracellular organelle;7.14433733136988e-114!GO:0044444;cytoplasmic part;1.33018355317257e-84!GO:0044422;organelle part;5.84386234552956e-72!GO:0005515;protein binding;2.03055724887678e-70!GO:0044446;intracellular organelle part;2.47602960638482e-70!GO:0044237;cellular metabolic process;6.90119917593132e-67!GO:0044238;primary metabolic process;5.39917365674445e-66!GO:0043170;macromolecule metabolic process;1.07926558960246e-64!GO:0032991;macromolecular complex;3.16283499833629e-58!GO:0003723;RNA binding;7.40864643358014e-53!GO:0005634;nucleus;1.17005246923755e-50!GO:0030529;ribonucleoprotein complex;4.50351323362777e-50!GO:0044428;nuclear part;1.45685368010743e-47!GO:0019538;protein metabolic process;2.01736261342098e-46!GO:0033036;macromolecule localization;5.31668152812643e-44!GO:0015031;protein transport;1.60505988246657e-43!GO:0045184;establishment of protein localization;1.98084188131753e-43!GO:0044267;cellular protein metabolic process;3.49276087787423e-43!GO:0044260;cellular macromolecule metabolic process;5.92783637855903e-43!GO:0008104;protein localization;4.5307794279131e-41!GO:0006412;translation;4.3243293913731e-39!GO:0043233;organelle lumen;1.46092227822969e-38!GO:0031974;membrane-enclosed lumen;1.46092227822969e-38!GO:0043283;biopolymer metabolic process;2.39178944913225e-36!GO:0005829;cytosol;4.66351520224409e-35!GO:0010467;gene expression;7.99169969825963e-35!GO:0031090;organelle membrane;3.72473356568051e-34!GO:0016071;mRNA metabolic process;4.42728727123587e-32!GO:0031981;nuclear lumen;2.82328564999084e-30!GO:0006396;RNA processing;5.01519022701926e-30!GO:0006915;apoptosis;9.21475616760116e-30!GO:0012501;programmed cell death;9.6881202420593e-30!GO:0009059;macromolecule biosynthetic process;1.12526368101524e-29!GO:0043234;protein complex;1.41550480056358e-29!GO:0046907;intracellular transport;3.24678233875037e-29!GO:0016043;cellular component organization and biogenesis;3.9039056548167e-29!GO:0006886;intracellular protein transport;4.56750027809032e-29!GO:0008380;RNA splicing;1.95024017178219e-28!GO:0008219;cell death;5.07649321868749e-28!GO:0016265;death;5.07649321868749e-28!GO:0006397;mRNA processing;1.46899376292853e-27!GO:0009058;biosynthetic process;1.58361321798218e-27!GO:0044249;cellular biosynthetic process;2.34218899531909e-27!GO:0005739;mitochondrion;4.93570622344211e-27!GO:0005840;ribosome;1.64982842348252e-26!GO:0031967;organelle envelope;1.95444028766986e-25!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.00778453602539e-25!GO:0031975;envelope;3.67837502376635e-25!GO:0003735;structural constituent of ribosome;1.512676405022e-24!GO:0033279;ribosomal subunit;2.17053391961139e-23!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.38346372464779e-23!GO:0051649;establishment of cellular localization;1.08742542458304e-22!GO:0005654;nucleoplasm;2.184692866103e-22!GO:0065003;macromolecular complex assembly;5.52965776649611e-22!GO:0051641;cellular localization;7.04381608219079e-22!GO:0044445;cytosolic part;1.37978584374092e-21!GO:0005681;spliceosome;9.78010896700675e-21!GO:0008134;transcription factor binding;1.81716281298581e-20!GO:0044429;mitochondrial part;4.06498382325341e-20!GO:0016192;vesicle-mediated transport;8.11723916077919e-20!GO:0000166;nucleotide binding;1.49584537346788e-19!GO:0042981;regulation of apoptosis;1.88402902695922e-19!GO:0043067;regulation of programmed cell death;3.844048106505e-19!GO:0044451;nucleoplasm part;7.17744029845969e-19!GO:0022607;cellular component assembly;9.64183906469929e-19!GO:0043412;biopolymer modification;2.60897136641427e-17!GO:0007243;protein kinase cascade;3.94803284735521e-17!GO:0044265;cellular macromolecule catabolic process;6.8742551746905e-17!GO:0006119;oxidative phosphorylation;9.14145700996313e-17!GO:0006512;ubiquitin cycle;1.15356814533155e-16!GO:0048770;pigment granule;1.2047277836361e-16!GO:0042470;melanosome;1.2047277836361e-16!GO:0005740;mitochondrial envelope;1.52992574377586e-16!GO:0005773;vacuole;2.35482622028234e-16!GO:0006464;protein modification process;3.33161070807433e-16!GO:0031966;mitochondrial membrane;4.87617777250875e-16!GO:0022613;ribonucleoprotein complex biogenesis and assembly;5.50394153103071e-16!GO:0016070;RNA metabolic process;7.33533581976181e-16!GO:0048523;negative regulation of cellular process;1.68055106849711e-15!GO:0003676;nucleic acid binding;2.07207411991765e-15!GO:0043687;post-translational protein modification;2.19724292867061e-15!GO:0019866;organelle inner membrane;3.97453754603227e-15!GO:0050794;regulation of cellular process;5.49930690986889e-15!GO:0007242;intracellular signaling cascade;6.49082684033858e-15!GO:0007249;I-kappaB kinase/NF-kappaB cascade;7.40298708282687e-15!GO:0006996;organelle organization and biogenesis;7.40298708282687e-15!GO:0022618;protein-RNA complex assembly;7.98453333947777e-15!GO:0000323;lytic vacuole;1.10827152742769e-14!GO:0005764;lysosome;1.10827152742769e-14!GO:0006605;protein targeting;1.19111930246649e-14!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.46677593251252e-14!GO:0016462;pyrophosphatase activity;1.68317725649866e-14!GO:0016817;hydrolase activity, acting on acid anhydrides;1.90165192636673e-14!GO:0016604;nuclear body;1.90165192636673e-14!GO:0017111;nucleoside-triphosphatase activity;2.44919124577067e-14!GO:0048519;negative regulation of biological process;4.4425217038809e-14!GO:0032553;ribonucleotide binding;5.79992900979283e-14!GO:0032555;purine ribonucleotide binding;5.79992900979283e-14!GO:0043285;biopolymer catabolic process;7.40201239880782e-14!GO:0019941;modification-dependent protein catabolic process;9.12005767433514e-14!GO:0043632;modification-dependent macromolecule catabolic process;9.12005767433514e-14!GO:0006511;ubiquitin-dependent protein catabolic process;1.1595483763223e-13!GO:0051603;proteolysis involved in cellular protein catabolic process;1.19870315868429e-13!GO:0044257;cellular protein catabolic process;1.37964351974623e-13!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.2638543506963e-13!GO:0009057;macromolecule catabolic process;2.55052952684204e-13!GO:0017076;purine nucleotide binding;2.84857703942916e-13!GO:0003712;transcription cofactor activity;4.18192969404877e-13!GO:0043069;negative regulation of programmed cell death;4.45464380653729e-13!GO:0005794;Golgi apparatus;4.74150253025581e-13!GO:0043066;negative regulation of apoptosis;5.3141114563198e-13!GO:0006913;nucleocytoplasmic transport;5.68337096502045e-13!GO:0015934;large ribosomal subunit;8.39510792387972e-13!GO:0044248;cellular catabolic process;9.04576790424839e-13!GO:0006793;phosphorus metabolic process;9.04576790424839e-13!GO:0006796;phosphate metabolic process;9.04576790424839e-13!GO:0065009;regulation of a molecular function;1.02815306054124e-12!GO:0051169;nuclear transport;1.08173658297135e-12!GO:0016874;ligase activity;1.15582414157986e-12!GO:0005743;mitochondrial inner membrane;1.17474009942077e-12!GO:0016607;nuclear speck;1.240521395384e-12!GO:0012505;endomembrane system;1.93952286240297e-12!GO:0005768;endosome;2.06927755750392e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.1114026752439e-12!GO:0008135;translation factor activity, nucleic acid binding;2.46058638616962e-12!GO:0000502;proteasome complex (sensu Eukaryota);3.74142875867471e-12!GO:0044455;mitochondrial membrane part;5.35039128199011e-12!GO:0051246;regulation of protein metabolic process;5.96155611515337e-12!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;7.09830527506939e-12!GO:0050789;regulation of biological process;7.49230401818406e-12!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);9.40757189374017e-12!GO:0006366;transcription from RNA polymerase II promoter;1.55813868917967e-11!GO:0015935;small ribosomal subunit;1.68530984415434e-11!GO:0016310;phosphorylation;2.1500591153293e-11!GO:0006457;protein folding;2.52480999846355e-11!GO:0003743;translation initiation factor activity;4.21359458243997e-11!GO:0002376;immune system process;4.27474897624241e-11!GO:0006259;DNA metabolic process;6.3485537606572e-11!GO:0030163;protein catabolic process;8.76321266679537e-11!GO:0006916;anti-apoptosis;9.94930615975388e-11!GO:0065007;biological regulation;2.04474166376544e-10!GO:0006950;response to stress;2.09959010440257e-10!GO:0006413;translational initiation;3.14195996106697e-10!GO:0005524;ATP binding;7.08348793447269e-10!GO:0051186;cofactor metabolic process;7.38719488125999e-10!GO:0006446;regulation of translational initiation;7.62710189483399e-10!GO:0031324;negative regulation of cellular metabolic process;8.10425672867609e-10!GO:0048193;Golgi vesicle transport;8.53228252336508e-10!GO:0032559;adenyl ribonucleotide binding;1.28510249257021e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.47926035022353e-09!GO:0005746;mitochondrial respiratory chain;1.5033602285131e-09!GO:0008639;small protein conjugating enzyme activity;2.66052832317604e-09!GO:0005783;endoplasmic reticulum;3.30002388627244e-09!GO:0019787;small conjugating protein ligase activity;3.51097417687954e-09!GO:0050790;regulation of catalytic activity;3.89476240212107e-09!GO:0005635;nuclear envelope;4.25439509474611e-09!GO:0000398;nuclear mRNA splicing, via spliceosome;4.927001657069e-09!GO:0000375;RNA splicing, via transesterification reactions;4.927001657069e-09!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;4.927001657069e-09!GO:0048522;positive regulation of cellular process;5.22833863022857e-09!GO:0004842;ubiquitin-protein ligase activity;5.53187056948718e-09!GO:0030554;adenyl nucleotide binding;6.21196401891028e-09!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;6.39220532000836e-09!GO:0019829;cation-transporting ATPase activity;7.02603135385709e-09!GO:0051082;unfolded protein binding;7.16556730261684e-09!GO:0050136;NADH dehydrogenase (quinone) activity;7.73188856080965e-09!GO:0003954;NADH dehydrogenase activity;7.73188856080965e-09!GO:0008137;NADH dehydrogenase (ubiquinone) activity;7.73188856080965e-09!GO:0006732;coenzyme metabolic process;7.73188856080965e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;8.03366005697755e-09!GO:0016787;hydrolase activity;1.04270402887623e-08!GO:0019222;regulation of metabolic process;1.12902888892708e-08!GO:0017038;protein import;1.1865413718012e-08!GO:0015986;ATP synthesis coupled proton transport;1.28405932899864e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.28405932899864e-08!GO:0006955;immune response;1.45669541263722e-08!GO:0005770;late endosome;1.71429265817773e-08!GO:0003713;transcription coactivator activity;1.87423771174875e-08!GO:0006417;regulation of translation;1.87423771174875e-08!GO:0009892;negative regulation of metabolic process;2.18366403516764e-08!GO:0009056;catabolic process;3.07436712959833e-08!GO:0007264;small GTPase mediated signal transduction;3.3632252769293e-08!GO:0048518;positive regulation of biological process;3.38862471332848e-08!GO:0009967;positive regulation of signal transduction;3.67116012240573e-08!GO:0051170;nuclear import;4.04634767583514e-08!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.45523610252552e-08!GO:0008047;enzyme activator activity;4.45523610252552e-08!GO:0016564;transcription repressor activity;4.46805863870641e-08!GO:0016481;negative regulation of transcription;4.60156295566389e-08!GO:0005730;nucleolus;5.67461247571156e-08!GO:0009152;purine ribonucleotide biosynthetic process;6.60143790412511e-08!GO:0016881;acid-amino acid ligase activity;7.29222142192267e-08!GO:0043065;positive regulation of apoptosis;7.30117409703027e-08!GO:0019899;enzyme binding;7.68846782512846e-08!GO:0008565;protein transporter activity;7.94165461265419e-08!GO:0005774;vacuolar membrane;7.94165461265419e-08!GO:0009150;purine ribonucleotide metabolic process;8.54456576660367e-08!GO:0006606;protein import into nucleus;9.21810406371831e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;9.98944397142419e-08!GO:0043068;positive regulation of programmed cell death;9.98944397142419e-08!GO:0042775;organelle ATP synthesis coupled electron transport;9.99112117645922e-08!GO:0042773;ATP synthesis coupled electron transport;9.99112117645922e-08!GO:0044440;endosomal part;1.03791009545014e-07!GO:0010008;endosome membrane;1.03791009545014e-07!GO:0007049;cell cycle;1.10086013305544e-07!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.35361978739971e-07!GO:0006164;purine nucleotide biosynthetic process;1.40765827413311e-07!GO:0031965;nuclear membrane;1.47252708973118e-07!GO:0006163;purine nucleotide metabolic process;1.5883240906425e-07!GO:0003924;GTPase activity;1.6339821902361e-07!GO:0044432;endoplasmic reticulum part;1.63681417811148e-07!GO:0006754;ATP biosynthetic process;1.63681417811148e-07!GO:0006753;nucleoside phosphate metabolic process;1.63681417811148e-07!GO:0016568;chromatin modification;1.65176413144304e-07!GO:0030964;NADH dehydrogenase complex (quinone);1.77775124523992e-07!GO:0045271;respiratory chain complex I;1.77775124523992e-07!GO:0005747;mitochondrial respiratory chain complex I;1.77775124523992e-07!GO:0006325;establishment and/or maintenance of chromatin architecture;1.92225315081034e-07!GO:0009259;ribonucleotide metabolic process;2.1659741033505e-07!GO:0016469;proton-transporting two-sector ATPase complex;2.17685863736377e-07!GO:0006461;protein complex assembly;2.29400329668859e-07!GO:0005525;GTP binding;2.30701953400545e-07!GO:0015078;hydrogen ion transmembrane transporter activity;2.49114650822857e-07!GO:0044453;nuclear membrane part;2.56840448566915e-07!GO:0043228;non-membrane-bound organelle;2.87231391617785e-07!GO:0043232;intracellular non-membrane-bound organelle;2.87231391617785e-07!GO:0016887;ATPase activity;3.38460877971071e-07!GO:0005793;ER-Golgi intermediate compartment;3.41441963006745e-07!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;3.68901421649288e-07!GO:0009260;ribonucleotide biosynthetic process;3.95919270984353e-07!GO:0042623;ATPase activity, coupled;4.26424207656704e-07!GO:0044437;vacuolar part;4.26424207656704e-07!GO:0009889;regulation of biosynthetic process;4.28443954212597e-07!GO:0005765;lysosomal membrane;5.53723336905144e-07!GO:0051726;regulation of cell cycle;5.58111803498202e-07!GO:0031326;regulation of cellular biosynthetic process;5.74868902587537e-07!GO:0006323;DNA packaging;5.88223367483855e-07!GO:0016044;membrane organization and biogenesis;5.91397339927288e-07!GO:0016563;transcription activator activity;6.66508169840106e-07!GO:0009966;regulation of signal transduction;6.90256525420763e-07!GO:0048468;cell development;7.05107980078799e-07!GO:0009055;electron carrier activity;7.17571654067092e-07!GO:0045786;negative regulation of progression through cell cycle;7.50137281865338e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;7.54196185510221e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;7.54196185510221e-07!GO:0000074;regulation of progression through cell cycle;8.79644394303426e-07!GO:0009615;response to virus;9.4635962885916e-07!GO:0009142;nucleoside triphosphate biosynthetic process;1.05474749168415e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.05474749168415e-06!GO:0046034;ATP metabolic process;1.10345566429019e-06!GO:0006917;induction of apoptosis;1.31520239533928e-06!GO:0051188;cofactor biosynthetic process;1.72257130875482e-06!GO:0031323;regulation of cellular metabolic process;1.72899691621572e-06!GO:0012502;induction of programmed cell death;2.15189915006153e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.47302337079862e-06!GO:0009144;purine nucleoside triphosphate metabolic process;2.47302337079862e-06!GO:0032446;protein modification by small protein conjugation;2.55263018671889e-06!GO:0006752;group transfer coenzyme metabolic process;2.86856777263346e-06!GO:0050657;nucleic acid transport;2.94924050435253e-06!GO:0051236;establishment of RNA localization;2.94924050435253e-06!GO:0050658;RNA transport;2.94924050435253e-06!GO:0009199;ribonucleoside triphosphate metabolic process;3.18204365221371e-06!GO:0031982;vesicle;3.34834233988816e-06!GO:0009108;coenzyme biosynthetic process;3.39077420517611e-06!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;3.90502916060846e-06!GO:0006403;RNA localization;4.10472489579312e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;4.39305804252017e-06!GO:0005839;proteasome core complex (sensu Eukaryota);4.5202229326858e-06!GO:0005789;endoplasmic reticulum membrane;4.65042061078292e-06!GO:0042175;nuclear envelope-endoplasmic reticulum network;4.65086899236579e-06!GO:0032561;guanyl ribonucleotide binding;4.76277174256454e-06!GO:0019001;guanyl nucleotide binding;4.76277174256454e-06!GO:0016567;protein ubiquitination;4.76277174256454e-06!GO:0048475;coated membrane;5.15209985788274e-06!GO:0030117;membrane coat;5.15209985788274e-06!GO:0009607;response to biotic stimulus;5.69468527030845e-06!GO:0006888;ER to Golgi vesicle-mediated transport;6.54684479766924e-06!GO:0003714;transcription corepressor activity;7.60467070254792e-06!GO:0016197;endosome transport;7.67156259819259e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;8.08079161372808e-06!GO:0005096;GTPase activator activity;8.12259419362398e-06!GO:0009141;nucleoside triphosphate metabolic process;8.57460525110486e-06!GO:0030695;GTPase regulator activity;8.80845669475967e-06!GO:0005643;nuclear pore;9.10719193553274e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;9.13927542318766e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;9.94408048174045e-06!GO:0051336;regulation of hydrolase activity;1.02240118754648e-05!GO:0030120;vesicle coat;1.21563834031818e-05!GO:0030662;coated vesicle membrane;1.21563834031818e-05!GO:0031252;leading edge;1.37024753210933e-05!GO:0006897;endocytosis;1.43393270808689e-05!GO:0010324;membrane invagination;1.43393270808689e-05!GO:0031980;mitochondrial lumen;1.67319179343972e-05!GO:0005759;mitochondrial matrix;1.67319179343972e-05!GO:0051276;chromosome organization and biogenesis;1.78018386004673e-05!GO:0005769;early endosome;1.94648618780043e-05!GO:0031410;cytoplasmic vesicle;2.28868195860659e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;2.42521408865772e-05!GO:0015399;primary active transmembrane transporter activity;2.42521408865772e-05!GO:0004298;threonine endopeptidase activity;2.46013693021139e-05!GO:0010468;regulation of gene expression;2.822347242858e-05!GO:0031902;late endosome membrane;2.95118408544306e-05!GO:0006974;response to DNA damage stimulus;3.44727587443953e-05!GO:0031988;membrane-bound vesicle;3.70460667474104e-05!GO:0051028;mRNA transport;3.90553571757656e-05!GO:0008632;apoptotic program;4.45360831057949e-05!GO:0008026;ATP-dependent helicase activity;4.492745571991e-05!GO:0006401;RNA catabolic process;5.34062565299726e-05!GO:0004674;protein serine/threonine kinase activity;6.29037904387226e-05!GO:0030036;actin cytoskeleton organization and biogenesis;6.46065169223142e-05!GO:0004386;helicase activity;6.66600867814064e-05!GO:0045259;proton-transporting ATP synthase complex;7.09176961972185e-05!GO:0001816;cytokine production;7.18918058737256e-05!GO:0051168;nuclear export;7.20661104537992e-05!GO:0006613;cotranslational protein targeting to membrane;7.22796438284034e-05!GO:0009060;aerobic respiration;9.29733308903778e-05!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;9.29733308903778e-05!GO:0022402;cell cycle process;9.41992236695573e-05!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;9.7593704575715e-05!GO:0045892;negative regulation of transcription, DNA-dependent;0.000100861418349998!GO:0046822;regulation of nucleocytoplasmic transport;0.000105609639189277!GO:0046930;pore complex;0.00010694256557635!GO:0032940;secretion by cell;0.000110252149216376!GO:0065002;intracellular protein transport across a membrane;0.000117953629045843!GO:0005083;small GTPase regulator activity;0.000120937787085649!GO:0016023;cytoplasmic membrane-bound vesicle;0.000124289318996814!GO:0007265;Ras protein signal transduction;0.000126064122777769!GO:0016740;transferase activity;0.000134958131907186!GO:0043566;structure-specific DNA binding;0.000149473424768699!GO:0005057;receptor signaling protein activity;0.0001601613104076!GO:0044431;Golgi apparatus part;0.000170727567699018!GO:0009893;positive regulation of metabolic process;0.000179869108707291!GO:0005798;Golgi-associated vesicle;0.000183773319131946!GO:0000151;ubiquitin ligase complex;0.000190303357768007!GO:0051427;hormone receptor binding;0.000192781751927554!GO:0003724;RNA helicase activity;0.000193861479262474!GO:0005885;Arp2/3 protein complex;0.000228801835011264!GO:0008234;cysteine-type peptidase activity;0.000236443321655963!GO:0051338;regulation of transferase activity;0.00024210326942613!GO:0000245;spliceosome assembly;0.000265068141481095!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.000265092624939466!GO:0006350;transcription;0.000269710737521578!GO:0007050;cell cycle arrest;0.000289887718328286!GO:0006818;hydrogen transport;0.000290028492277361!GO:0035257;nuclear hormone receptor binding;0.000314143918261387!GO:0046519;sphingoid metabolic process;0.000337874255152908!GO:0043492;ATPase activity, coupled to movement of substances;0.000338795155281929!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000341163312189717!GO:0045333;cellular respiration;0.000358234102703653!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.000368383026703002!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000372739480903412!GO:0030532;small nuclear ribonucleoprotein complex;0.000384027755896423!GO:0030099;myeloid cell differentiation;0.000392830445217234!GO:0015992;proton transport;0.000409825896545329!GO:0007040;lysosome organization and biogenesis;0.000409825896545329!GO:0006281;DNA repair;0.000425567753325247!GO:0008654;phospholipid biosynthetic process;0.000432362519169052!GO:0003729;mRNA binding;0.000443425959730279!GO:0006402;mRNA catabolic process;0.000466593086362383!GO:0006672;ceramide metabolic process;0.000490843312285764!GO:0007005;mitochondrion organization and biogenesis;0.000500553133936997!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000512660277080894!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000516841769497647!GO:0043085;positive regulation of catalytic activity;0.000530532332280072!GO:0022890;inorganic cation transmembrane transporter activity;0.00053410002672727!GO:0003697;single-stranded DNA binding;0.000534777219301394!GO:0007034;vacuolar transport;0.000534777219301394!GO:0043549;regulation of kinase activity;0.000553337544825142!GO:0006643;membrane lipid metabolic process;0.000568955084379556!GO:0001726;ruffle;0.00057489340192326!GO:0051223;regulation of protein transport;0.000596851327405833!GO:0060090;molecular adaptor activity;0.000619858522973112!GO:0051789;response to protein stimulus;0.000670130593056444!GO:0006986;response to unfolded protein;0.000670130593056444!GO:0030029;actin filament-based process;0.000708229615726925!GO:0016301;kinase activity;0.000708229615726925!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.000728365814282703!GO:0045941;positive regulation of transcription;0.00076682703833088!GO:0005741;mitochondrial outer membrane;0.000773043033738474!GO:0005667;transcription factor complex;0.000775950340495889!GO:0002757;immune response-activating signal transduction;0.000776169435954176!GO:0009117;nucleotide metabolic process;0.000796789666658556!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000810536426411206!GO:0044262;cellular carbohydrate metabolic process;0.000851754699299812!GO:0046983;protein dimerization activity;0.00086528956888839!GO:0006612;protein targeting to membrane;0.000880551919907149!GO:0045859;regulation of protein kinase activity;0.000897970641408872!GO:0007033;vacuole organization and biogenesis;0.000897970641408872!GO:0043087;regulation of GTPase activity;0.000922715798380839!GO:0033157;regulation of intracellular protein transport;0.00094078712190189!GO:0042306;regulation of protein import into nucleus;0.00094078712190189!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000961310173903089!GO:0045893;positive regulation of transcription, DNA-dependent;0.000971675184583544!GO:0051090;regulation of transcription factor activity;0.00100999161682381!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00107335851033766!GO:0005099;Ras GTPase activator activity;0.00107492227628797!GO:0065004;protein-DNA complex assembly;0.00107738225819431!GO:0042254;ribosome biogenesis and assembly;0.00114254497693888!GO:0030149;sphingolipid catabolic process;0.0011668730259313!GO:0005761;mitochondrial ribosome;0.00118877844550723!GO:0000313;organellar ribosome;0.00118877844550723!GO:0006954;inflammatory response;0.00121484736584169!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00121484736584169!GO:0043281;regulation of caspase activity;0.00122277705330888!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00126861039048856!GO:0033116;ER-Golgi intermediate compartment membrane;0.00131236464056352!GO:0005637;nuclear inner membrane;0.00135239702974592!GO:0007041;lysosomal transport;0.00149878418607918!GO:0043623;cellular protein complex assembly;0.00149907054752171!GO:0006919;caspase activation;0.00153220463082118!GO:0031325;positive regulation of cellular metabolic process;0.00161292320043492!GO:0045637;regulation of myeloid cell differentiation;0.00164864034951255!GO:0043280;positive regulation of caspase activity;0.00179125860589365!GO:0002764;immune response-regulating signal transduction;0.00184027044177012!GO:0008186;RNA-dependent ATPase activity;0.00193486803046624!GO:0019904;protein domain specific binding;0.00201113020143474!GO:0002274;myeloid leukocyte activation;0.00207099518201872!GO:0022415;viral reproductive process;0.00211671893335056!GO:0009719;response to endogenous stimulus;0.00220552560736993!GO:0006468;protein amino acid phosphorylation;0.00225935832733552!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00229897444200976!GO:0019867;outer membrane;0.00236600192291939!GO:0030041;actin filament polymerization;0.00242891013401872!GO:0006333;chromatin assembly or disassembly;0.00257593016715235!GO:0019221;cytokine and chemokine mediated signaling pathway;0.0025894222075826!GO:0016251;general RNA polymerase II transcription factor activity;0.0025894222075826!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00262757581243554!GO:0042990;regulation of transcription factor import into nucleus;0.00264351968150201!GO:0042991;transcription factor import into nucleus;0.00264351968150201!GO:0031968;organelle outer membrane;0.00287030146724638!GO:0048487;beta-tubulin binding;0.00291818812460147!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.00294000962542962!GO:0004812;aminoacyl-tRNA ligase activity;0.00294000962542962!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.00294000962542962!GO:0006099;tricarboxylic acid cycle;0.00309917557475639!GO:0046356;acetyl-CoA catabolic process;0.00309917557475639!GO:0051707;response to other organism;0.00309917557475639!GO:0016363;nuclear matrix;0.00316271347522586!GO:0045045;secretory pathway;0.00351940171763344!GO:0031901;early endosome membrane;0.00359893534900474!GO:0045321;leukocyte activation;0.00382172628367848!GO:0046966;thyroid hormone receptor binding;0.0039244299704428!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.00397813562150062!GO:0045454;cell redox homeostasis;0.00412409179310161!GO:0051187;cofactor catabolic process;0.00415339701341073!GO:0000139;Golgi membrane;0.00430637523386835!GO:0001817;regulation of cytokine production;0.00433643342080158!GO:0030097;hemopoiesis;0.00433643342080158!GO:0006891;intra-Golgi vesicle-mediated transport;0.00468616703369189!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00477170995158586!GO:0043021;ribonucleoprotein binding;0.00479910765346389!GO:0031072;heat shock protein binding;0.00479910765346389!GO:0018193;peptidyl-amino acid modification;0.00481430638097091!GO:0043038;amino acid activation;0.00484322736582817!GO:0006418;tRNA aminoacylation for protein translation;0.00484322736582817!GO:0043039;tRNA aminoacylation;0.00484322736582817!GO:0006352;transcription initiation;0.00485688211700096!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00489939315192617!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00489939315192617!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00489939315192617!GO:0004004;ATP-dependent RNA helicase activity;0.0050906944421524!GO:0006399;tRNA metabolic process;0.00510873249771556!GO:0005070;SH3/SH2 adaptor activity;0.00525238930727893!GO:0032318;regulation of Ras GTPase activity;0.00525238930727893!GO:0004197;cysteine-type endopeptidase activity;0.00529278203409704!GO:0045449;regulation of transcription;0.00554566335327268!GO:0004185;serine carboxypeptidase activity;0.0056094245937488!GO:0005813;centrosome;0.00565232514880702!GO:0030658;transport vesicle membrane;0.00577870695254859!GO:0006084;acetyl-CoA metabolic process;0.00579467834058781!GO:0019377;glycolipid catabolic process;0.00615389760104372!GO:0051252;regulation of RNA metabolic process;0.00622280686501211!GO:0005484;SNAP receptor activity;0.00645545024848586!GO:0033367;protein localization in mast cell secretory granule;0.00645545024848586!GO:0033365;protein localization in organelle;0.00645545024848586!GO:0033371;T cell secretory granule organization and biogenesis;0.00645545024848586!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.00645545024848586!GO:0033375;protease localization in T cell secretory granule;0.00645545024848586!GO:0042629;mast cell granule;0.00645545024848586!GO:0033377;maintenance of protein localization in T cell secretory granule;0.00645545024848586!GO:0033364;mast cell secretory granule organization and biogenesis;0.00645545024848586!GO:0033380;granzyme B localization in T cell secretory granule;0.00645545024848586!GO:0033379;maintenance of protease localization in T cell secretory granule;0.00645545024848586!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.00645545024848586!GO:0033368;protease localization in mast cell secretory granule;0.00645545024848586!GO:0033366;protein localization in secretory granule;0.00645545024848586!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.00645545024848586!GO:0033374;protein localization in T cell secretory granule;0.00645545024848586!GO:0051345;positive regulation of hydrolase activity;0.0066101331179384!GO:0007259;JAK-STAT cascade;0.00691089674814093!GO:0006611;protein export from nucleus;0.00752198777955941!GO:0043433;negative regulation of transcription factor activity;0.00781331271620143!GO:0030867;rough endoplasmic reticulum membrane;0.00786297549230085!GO:0008383;manganese superoxide dismutase activity;0.007912930779394!GO:0001315;age-dependent response to reactive oxygen species;0.007912930779394!GO:0006351;transcription, DNA-dependent;0.00808702685680967!GO:0009165;nucleotide biosynthetic process;0.00808702685680967!GO:0006952;defense response;0.00821877677996953!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.00840284164223025!GO:0042802;identical protein binding;0.00844581916436961!GO:0032774;RNA biosynthetic process;0.00862705594717097!GO:0000785;chromatin;0.00880411022847664!GO:0006665;sphingolipid metabolic process;0.00906037374926164!GO:0032386;regulation of intracellular transport;0.00937631806858522!GO:0006458;'de novo' protein folding;0.00938253128605286!GO:0051084;'de novo' posttranslational protein folding;0.00938253128605286!GO:0019318;hexose metabolic process;0.00962028766012481!GO:0030118;clathrin coat;0.00977465935543093!GO:0008624;induction of apoptosis by extracellular signals;0.0098367862513916!GO:0015631;tubulin binding;0.00988282825952335!GO:0031625;ubiquitin protein ligase binding;0.00992183610835758!GO:0003690;double-stranded DNA binding;0.010038221879352!GO:0048471;perinuclear region of cytoplasm;0.0104476643579168!GO:0009109;coenzyme catabolic process;0.0105884037707906!GO:0030134;ER to Golgi transport vesicle;0.0114564842608473!GO:0006607;NLS-bearing substrate import into nucleus;0.0114835944369096!GO:0030127;COPII vesicle coat;0.0115278899877531!GO:0012507;ER to Golgi transport vesicle membrane;0.0115278899877531!GO:0046467;membrane lipid biosynthetic process;0.0116805463317213!GO:0048500;signal recognition particle;0.0118107826998381!GO:0030518;steroid hormone receptor signaling pathway;0.0121451401977561!GO:0005996;monosaccharide metabolic process;0.0121587762798491!GO:0051092;activation of NF-kappaB transcription factor;0.0121587762798491!GO:0046479;glycosphingolipid catabolic process;0.0121587762798491!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.012188439237858!GO:0006091;generation of precursor metabolites and energy;0.0123023831108063!GO:0000082;G1/S transition of mitotic cell cycle;0.0123023831108063!GO:0019079;viral genome replication;0.0123801268918397!GO:0016779;nucleotidyltransferase activity;0.0124135401739962!GO:0030218;erythrocyte differentiation;0.0126286336917384!GO:0046466;membrane lipid catabolic process;0.0132081020920939!GO:0006354;RNA elongation;0.0132554774693385!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0134141492730479!GO:0016791;phosphoric monoester hydrolase activity;0.0135243309907197!GO:0019882;antigen processing and presentation;0.0135243309907197!GO:0030027;lamellipodium;0.0135491950262501!GO:0006650;glycerophospholipid metabolic process;0.0137847051008818!GO:0030660;Golgi-associated vesicle membrane;0.0141529569786057!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0145902675705466!GO:0001819;positive regulation of cytokine production;0.014721094016247!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0152256099795036!GO:0002819;regulation of adaptive immune response;0.0152256099795036!GO:0043621;protein self-association;0.0156353380862834!GO:0005048;signal sequence binding;0.0157641416819097!GO:0005905;coated pit;0.0158955868890592!GO:0050811;GABA receptor binding;0.0159404808038086!GO:0043488;regulation of mRNA stability;0.0160613575189692!GO:0043487;regulation of RNA stability;0.0160613575189692!GO:0030176;integral to endoplasmic reticulum membrane;0.0164180156125642!GO:0016072;rRNA metabolic process;0.0164429795752381!GO:0050851;antigen receptor-mediated signaling pathway;0.0167238832936849!GO:0030663;COPI coated vesicle membrane;0.0172386143890497!GO:0030126;COPI vesicle coat;0.0172386143890497!GO:0005815;microtubule organizing center;0.0173447897667601!GO:0032763;regulation of mast cell cytokine production;0.01749213181786!GO:0032762;mast cell cytokine production;0.01749213181786!GO:0004177;aminopeptidase activity;0.0176729105518739!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0180887656438787!GO:0045047;protein targeting to ER;0.0180887656438787!GO:0002440;production of molecular mediator of immune response;0.0181648824592206!GO:0006914;autophagy;0.0183816197656386!GO:0005694;chromosome;0.0184839942050527!GO:0006644;phospholipid metabolic process;0.018590066988331!GO:0008154;actin polymerization and/or depolymerization;0.0188247082444104!GO:0033673;negative regulation of kinase activity;0.0189349188718319!GO:0006469;negative regulation of protein kinase activity;0.0189349188718319!GO:0019883;antigen processing and presentation of endogenous antigen;0.0189349188718319!GO:0008637;apoptotic mitochondrial changes;0.0190336659925715!GO:0000209;protein polyubiquitination;0.0190336659925715!GO:0030521;androgen receptor signaling pathway;0.0193787676630485!GO:0043022;ribosome binding;0.0196549490971561!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0196647992333265!GO:0006364;rRNA processing;0.0198542376247064!GO:0030503;regulation of cell redox homeostasis;0.0200090818712486!GO:0030137;COPI-coated vesicle;0.0200783835856031!GO:0000287;magnesium ion binding;0.0200783835856031!GO:0008139;nuclear localization sequence binding;0.0202608349109869!GO:0006516;glycoprotein catabolic process;0.0203963578342659!GO:0042613;MHC class II protein complex;0.0205441459803608!GO:0002224;toll-like receptor signaling pathway;0.021234369570524!GO:0002221;pattern recognition receptor signaling pathway;0.021234369570524!GO:0004860;protein kinase inhibitor activity;0.0213771793140001!GO:0030133;transport vesicle;0.0215641108394861!GO:0009611;response to wounding;0.0216446674710258!GO:0002467;germinal center formation;0.0216446674710258!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0217868287107478!GO:0035035;histone acetyltransferase binding;0.0217902011275619!GO:0003702;RNA polymerase II transcription factor activity;0.0226042596486809!GO:0048002;antigen processing and presentation of peptide antigen;0.0226335804647404!GO:0002444;myeloid leukocyte mediated immunity;0.0236266275474493!GO:0051348;negative regulation of transferase activity;0.0237161519648598!GO:0051098;regulation of binding;0.0238576110301867!GO:0017166;vinculin binding;0.0241858275161033!GO:0045792;negative regulation of cell size;0.0246108387559905!GO:0050900;leukocyte migration;0.024886280056985!GO:0008625;induction of apoptosis via death domain receptors;0.0249627935202626!GO:0003746;translation elongation factor activity;0.0250690684932063!GO:0006414;translational elongation;0.0252171009719784!GO:0019843;rRNA binding;0.0252696842654472!GO:0051059;NF-kappaB binding;0.0252828179699126!GO:0043300;regulation of leukocyte degranulation;0.02577879434953!GO:0046578;regulation of Ras protein signal transduction;0.0260146017203829!GO:0051085;chaperone cofactor-dependent protein folding;0.0265256288095131!GO:0030100;regulation of endocytosis;0.0265737142331137!GO:0033033;negative regulation of myeloid cell apoptosis;0.0265737142331137!GO:0001803;regulation of type III hypersensitivity;0.0265737142331137!GO:0032733;positive regulation of interleukin-10 production;0.0265737142331137!GO:0033025;regulation of mast cell apoptosis;0.0265737142331137!GO:0001805;positive regulation of type III hypersensitivity;0.0265737142331137!GO:0033023;mast cell homeostasis;0.0265737142331137!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.0265737142331137!GO:0033032;regulation of myeloid cell apoptosis;0.0265737142331137!GO:0001802;type III hypersensitivity;0.0265737142331137!GO:0033028;myeloid cell apoptosis;0.0265737142331137!GO:0042590;antigen processing and presentation of exogenous peptide antigen via MHC class I;0.0265737142331137!GO:0033026;negative regulation of mast cell apoptosis;0.0265737142331137!GO:0033024;mast cell apoptosis;0.0265737142331137!GO:0030384;phosphoinositide metabolic process;0.0266377144110971!GO:0045646;regulation of erythrocyte differentiation;0.0267313733869953!GO:0051091;positive regulation of transcription factor activity;0.0267313733869953!GO:0019220;regulation of phosphate metabolic process;0.0268059302983078!GO:0051174;regulation of phosphorus metabolic process;0.0268059302983078!GO:0051056;regulation of small GTPase mediated signal transduction;0.0269817360410756!GO:0000339;RNA cap binding;0.0271457618449631!GO:0006405;RNA export from nucleus;0.0274386120605475!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0276718815795975!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0276718815795975!GO:0015923;mannosidase activity;0.0279982889684838!GO:0051049;regulation of transport;0.0288630964201875!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0289027485513178!GO:0000165;MAPKKK cascade;0.0289934835145556!GO:0005869;dynactin complex;0.0290134117067456!GO:0045576;mast cell activation;0.0294723299231446!GO:0051101;regulation of DNA binding;0.0296583236339871!GO:0002718;regulation of cytokine production during immune response;0.0297347824709091!GO:0002367;cytokine production during immune response;0.0297347824709091!GO:0002700;regulation of production of molecular mediator of immune response;0.0297347824709091!GO:0006749;glutathione metabolic process;0.0297347824709091!GO:0006007;glucose catabolic process;0.0297347824709091!GO:0030308;negative regulation of cell growth;0.0299087299942569!GO:0030258;lipid modification;0.0303749377334092!GO:0030119;AP-type membrane coat adaptor complex;0.0304403997179471!GO:0051045;negative regulation of membrane protein ectodomain proteolysis;0.0304403997179471!GO:0051043;regulation of membrane protein ectodomain proteolysis;0.0304403997179471!GO:0008286;insulin receptor signaling pathway;0.0309784195846659!GO:0002237;response to molecule of bacterial origin;0.0310003985310272!GO:0032640;tumor necrosis factor production;0.0310003985310272!GO:0015036;disulfide oxidoreductase activity;0.0310842548866694!GO:0045603;positive regulation of endothelial cell differentiation;0.0314392535053356!GO:0006376;mRNA splice site selection;0.0315255420037063!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0315255420037063!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0321537010859372!GO:0002520;immune system development;0.0321537010859372!GO:0045113;regulation of integrin biosynthetic process;0.0322977397319875!GO:0045112;integrin biosynthetic process;0.0322977397319875!GO:0051235;maintenance of localization;0.0325449129433488!GO:0000278;mitotic cell cycle;0.032681518007725!GO:0032760;positive regulation of tumor necrosis factor production;0.0327082468576283!GO:0016311;dephosphorylation;0.0328614584165542!GO:0008312;7S RNA binding;0.0329265927945102!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0329520050813073!GO:0006689;ganglioside catabolic process;0.0329891096244534!GO:0008656;caspase activator activity;0.0330241777209544!GO:0042110;T cell activation;0.0338863983593515!GO:0004722;protein serine/threonine phosphatase activity;0.0339760528724822!GO:0017091;AU-rich element binding;0.0340582251724406!GO:0050779;RNA destabilization;0.0340582251724406!GO:0000289;poly(A) tail shortening;0.0340582251724406!GO:0001775;cell activation;0.0340801595997141!GO:0003725;double-stranded RNA binding;0.0341741740286322!GO:0008287;protein serine/threonine phosphatase complex;0.0346985240644881!GO:0051347;positive regulation of transferase activity;0.0348119880601468!GO:0045639;positive regulation of myeloid cell differentiation;0.0351463797771075!GO:0046474;glycerophospholipid biosynthetic process;0.0351874730142439!GO:0043299;leukocyte degranulation;0.0353753566992223!GO:0004563;beta-N-acetylhexosaminidase activity;0.0354890853193319!GO:0005788;endoplasmic reticulum lumen;0.035519694918954!GO:0046649;lymphocyte activation;0.0359277589366619!GO:0008017;microtubule binding;0.0359904786072956!GO:0004672;protein kinase activity;0.0361312050029125!GO:0008270;zinc ion binding;0.0372103910348799!GO:0006509;membrane protein ectodomain proteolysis;0.0372548838087269!GO:0033619;membrane protein proteolysis;0.0372548838087269!GO:0019210;kinase inhibitor activity;0.0372752318949971!GO:0005669;transcription factor TFIID complex;0.0376813230681392!GO:0004218;cathepsin S activity;0.0386338935789485!GO:0002521;leukocyte differentiation;0.0398267037829564!GO:0009306;protein secretion;0.0399169237168921!GO:0008361;regulation of cell size;0.0399169237168921!GO:0002252;immune effector process;0.0401768916720876!GO:0048534;hemopoietic or lymphoid organ development;0.0403286660536737!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0404242580824161!GO:0044255;cellular lipid metabolic process;0.0407292524813038!GO:0042611;MHC protein complex;0.0410720205432179!GO:0000118;histone deacetylase complex;0.041350098133579!GO:0042348;NF-kappaB import into nucleus;0.0415890070246129!GO:0042345;regulation of NF-kappaB import into nucleus;0.0415890070246129!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0418224794532239!GO:0030374;ligand-dependent nuclear receptor transcription coactivator activity;0.0418224794532239!GO:0003711;transcription elongation regulator activity;0.0418224794532239!GO:0015980;energy derivation by oxidation of organic compounds;0.0422396119494958!GO:0006355;regulation of transcription, DNA-dependent;0.0423888570833658!GO:0048146;positive regulation of fibroblast proliferation;0.0426095195609811!GO:0030522;intracellular receptor-mediated signaling pathway;0.0427788058125165!GO:0030131;clathrin adaptor complex;0.0427788058125165!GO:0045309;protein phosphorylated amino acid binding;0.04322794019199!GO:0008538;proteasome activator activity;0.0435922681698514!GO:0031327;negative regulation of cellular biosynthetic process;0.0437804245652626!GO:0004702;receptor signaling protein serine/threonine kinase activity;0.0439934992394983!GO:0006006;glucose metabolic process;0.0441240183620599!GO:0005791;rough endoplasmic reticulum;0.0447068508962795!GO:0004704;NF-kappaB-inducing kinase activity;0.0452423752366545!GO:0048144;fibroblast proliferation;0.0452423752366545!GO:0048145;regulation of fibroblast proliferation;0.0452423752366545!GO:0006979;response to oxidative stress;0.0454476243421449!GO:0045920;negative regulation of exocytosis;0.0454476243421449!GO:0043301;negative regulation of leukocyte degranulation;0.0454476243421449!GO:0043305;negative regulation of mast cell degranulation;0.0454476243421449!GO:0008320;protein transmembrane transporter activity;0.0454659069487593!GO:0005975;carbohydrate metabolic process;0.0460299200507127!GO:0019901;protein kinase binding;0.04786392409446!GO:0032507;maintenance of cellular protein localization;0.0481682845212295!GO:0046489;phosphoinositide biosynthetic process;0.0482613349837768!GO:0045746;negative regulation of Notch signaling pathway;0.04912501961108!GO:0002824;positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0493641273639124!GO:0002821;positive regulation of adaptive immune response;0.0493641273639124!GO:0019058;viral infectious cycle;0.0494807996371358!GO:0051920;peroxiredoxin activity;0.049924525318057 | |||
|sample_id=11867 | |||
|sample_note= | |||
|sample_sex=female | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue= | |||
|top_motifs=NFE2L2:3.05565922334;NFE2:2.92374304945;BACH2:2.76063540988;SPI1:2.7302077956;SREBF1,2:2.72290143794;CEBPA,B_DDIT3:2.71356017814;FOSL2:2.66910252537;SPIB:2.64666754326;EP300:2.56269659627;PAX2:2.53174746634;FOS_FOS{B,L1}_JUN{B,D}:2.50855572793;FOXP3:2.40863558322;NANOG{mouse}:2.30801396218;ETS1,2:2.18676015995;HLF:2.1732758532;NFE2L1:2.08000935595;ATF5_CREB3:1.97869973617;DMAP1_NCOR{1,2}_SMARC:1.96893427901;NFIL3:1.90414403473;NR1H4:1.86070886273;FOXN1:1.80729264399;ATF4:1.77864271789;RUNX1..3:1.76712680517;NFKB1_REL_RELA:1.70412806705;RXRA_VDR{dimer}:1.61274054066;FOXD3:1.57537995714;ELF1,2,4:1.52144325648;ATF6:1.51887729897;HMX1:1.3847005452;ESRRA:1.27230272643;IRF1,2:1.22990238642;PPARG:1.21301977377;MAFB:1.1516079885;HES1:1.13083988556;SMAD1..7,9:1.09701222705;CREB1:1.09344169022;JUN:1.01192570477;PDX1:0.999952151332;PITX1..3:0.999772515729;TFCP2:0.977243212317;GLI1..3:0.864300680472;NR6A1:0.841662093732;BPTF:0.788812813411;ESR1:0.778287907605;TGIF1:0.764816766595;HIF1A:0.733505977248;TLX2:0.728442784487;FOXO1,3,4:0.722125113801;CDX1,2,4:0.644081547484;ALX4:0.615370526605;SPZ1:0.595505822371;STAT2,4,6:0.586307341386;IRF7:0.552314768722;ZBTB16:0.488040575416;HMGA1,2:0.450531316998;ATF2:0.433364057585;PAX4:0.377510054695;FOX{F1,F2,J1}:0.352824147595;IKZF2:0.328203306135;PAX1,9:0.232739292859;ALX1:0.222855662653;NANOG:0.15155972878;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.14035877931;RFX2..5_RFXANK_RFXAP:0.136860023115;RREB1:0.136552242401;PRDM1:0.113998735482;FOX{D1,D2}:0.104486732295;XBP1:0.09963515171;HBP1_HMGB_SSRP1_UBTF:0.0882506057854;GATA4:0.0745941883237;EN1,2:0.0596442360634;FOXP1:0.0500697953098;PAX3,7:0.00330525678802;NFATC1..3:-0.0294524269776;HSF1,2:-0.0681488028041;MYB:-0.0802509472538;HOX{A5,B5}:-0.0848420759494;PAX8:-0.0996186676607;RXR{A,B,G}:-0.114587101411;TFAP4:-0.119606301513;FOXL1:-0.19029099805;NKX2-2,8:-0.198725861833;ZBTB6:-0.226027069954;ZIC1..3:-0.244795529832;NFIX:-0.279325124138;AHR_ARNT_ARNT2:-0.303786185168;SRF:-0.317570001184;TBP:-0.321632069357;NKX3-1:-0.409196402533;HNF4A_NR2F1,2:-0.432479185005;MZF1:-0.438701877648;NKX3-2:-0.448688845932;ZNF148:-0.453303182414;MYFfamily:-0.473785340338;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.474348461677;DBP:-0.479228284889;PATZ1:-0.494089446635;OCT4_SOX2{dimer}:-0.533086788093;TAL1_TCF{3,4,12}:-0.541611894787;STAT5{A,B}:-0.554327536987;EGR1..3:-0.576778075649;MEF2{A,B,C,D}:-0.635236298257;FOXM1:-0.646277252744;TOPORS:-0.647550815144;REST:-0.678412931108;HNF1A:-0.704624747319;AIRE:-0.725917908148;NKX6-1,2:-0.728978270944;T:-0.730040996543;UFEwm:-0.747128128775;TBX4,5:-0.749089539209;ZNF238:-0.756993941223;IKZF1:-0.775530481961;HOXA9_MEIS1:-0.779002424681;GCM1,2:-0.795351854282;POU5F1:-0.854176032421;EVI1:-0.891274721094;MED-1{core}:-0.906393969074;NHLH1,2:-0.952061290181;PRRX1,2:-0.95249028043;VSX1,2:-0.987333101336;TFAP2{A,C}:-0.999765610143;POU2F1..3:-1.00578683313;GZF1:-1.03659385002;KLF4:-1.07069364487;EBF1:-1.07408172245;FOXA2:-1.11889077399;SOX2:-1.1202073302;MTF1:-1.12224852771;ZFP161:-1.12295594319;GATA6:-1.13039831377;POU6F1:-1.13263846438;ZNF423:-1.13615033361;CUX2:-1.1446824169;MYOD1:-1.14754483395;MTE{core}:-1.17913989299;TEF:-1.21820806619;TLX1..3_NFIC{dimer}:-1.21966897837;SOX5:-1.22029826619;RFX1:-1.22151757912;GTF2A1,2:-1.24283578014;PAX6:-1.28613710641;SP1:-1.29793126724;GTF2I:-1.33778443634;TFAP2B:-1.33976379606;TP53:-1.3421385196;STAT1,3:-1.35498915138;RBPJ:-1.3609628613;NKX2-1,4:-1.37191153709;LMO2:-1.38494530645;TEAD1:-1.39709788421;MAZ:-1.41078430852;ZEB1:-1.41863075546;PAX5:-1.4310636884;ARID5B:-1.45227222573;ZNF384:-1.47100761452;SOX{8,9,10}:-1.50455646929;RORA:-1.52225389223;TFDP1:-1.53935818916;HIC1:-1.54609064802;ONECUT1,2:-1.54894613006;XCPE1{core}:-1.58594981351;E2F1..5:-1.59725678739;ELK1,4_GABP{A,B1}:-1.59908004565;SNAI1..3:-1.6059675099;BREu{core}:-1.62774945351;CRX:-1.65488232999;NKX2-3_NKX2-5:-1.66210185436;AR:-1.7027976308;HOX{A4,D4}:-1.71379455024;NR3C1:-1.72241267987;HAND1,2:-1.74091825246;ADNP_IRX_SIX_ZHX:-1.76927710371;NR5A1,2:-1.77738258832;MYBL2:-1.93111928713;HOX{A6,A7,B6,B7}:-1.93336574963;FOXQ1:-1.97847317459;YY1:-2.00377121914;POU1F1:-2.04665307311;FOX{I1,J2}:-2.08200939946;GFI1B:-2.42783276087;POU3F1..4:-2.43552202255;bHLH_family:-2.44740387168;NFY{A,B,C}:-2.46981492723;SOX17:-2.4872280973;LHX3,4:-2.54382363259;PBX1:-2.6250133259;NRF1:-2.68226632333;GFI1:-2.83715091918;CDC5L:-2.84598560704;ZNF143:-3.0233602643;LEF1_TCF7_TCF7L1,2:-3.07748302585 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11867-125B4;search_select_hide=table117:FF:11867-125B4 | |||
}} | }} |
Latest revision as of 18:24, 4 June 2020
Name: | CD14+ monocytes - treated with Cryptococcus, donor1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13472 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13472
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13472
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0921 |
10 | 10 | 0.0236 |
100 | 100 | 0.816 |
101 | 101 | 0.87 |
102 | 102 | 0.523 |
103 | 103 | 0.275 |
104 | 104 | 0.564 |
105 | 105 | 0.254 |
106 | 106 | 5.59661e-4 |
107 | 107 | 0.164 |
108 | 108 | 0.868 |
109 | 109 | 0.201 |
11 | 11 | 0.115 |
110 | 110 | 0.256 |
111 | 111 | 0.0201 |
112 | 112 | 0.242 |
113 | 113 | 0.586 |
114 | 114 | 0.011 |
115 | 115 | 0.427 |
116 | 116 | 0.717 |
117 | 117 | 0.0461 |
118 | 118 | 0.174 |
119 | 119 | 0.142 |
12 | 12 | 0.352 |
120 | 120 | 0.985 |
121 | 121 | 0.496 |
122 | 122 | 0.736 |
123 | 123 | 0.0857 |
124 | 124 | 0.53 |
125 | 125 | 0.395 |
126 | 126 | 0.218 |
127 | 127 | 0.295 |
128 | 128 | 0.0164 |
129 | 129 | 0.524 |
13 | 13 | 0.18 |
130 | 130 | 0.124 |
131 | 131 | 0.656 |
132 | 132 | 0.108 |
133 | 133 | 0.699 |
134 | 134 | 0.536 |
135 | 135 | 0.331 |
136 | 136 | 0.836 |
137 | 137 | 0.00948 |
138 | 138 | 0.192 |
139 | 139 | 0.018 |
14 | 14 | 0.467 |
140 | 140 | 0.0946 |
141 | 141 | 0.341 |
142 | 142 | 0.462 |
143 | 143 | 0.0171 |
144 | 144 | 0.684 |
145 | 145 | 0.4 |
146 | 146 | 0.439 |
147 | 147 | 0.423 |
148 | 148 | 0.00773 |
149 | 149 | 0.581 |
15 | 15 | 0.135 |
150 | 150 | 0.474 |
151 | 151 | 0.306 |
152 | 152 | 0.139 |
153 | 153 | 0.509 |
154 | 154 | 0.58 |
155 | 155 | 0.326 |
156 | 156 | 0.792 |
157 | 157 | 0.285 |
158 | 158 | 0.0556 |
159 | 159 | 0.918 |
16 | 16 | 0.303 |
160 | 160 | 0.356 |
161 | 161 | 0.474 |
162 | 162 | 0.531 |
163 | 163 | 0.188 |
164 | 164 | 0.0862 |
165 | 165 | 0.162 |
166 | 166 | 0.52 |
167 | 167 | 0.214 |
168 | 168 | 0.34 |
169 | 169 | 0.0073 |
17 | 17 | 0.165 |
18 | 18 | 0.11 |
19 | 19 | 0.272 |
2 | 2 | 0.974 |
20 | 20 | 0.336 |
21 | 21 | 0.349 |
22 | 22 | 0.219 |
23 | 23 | 0.0406 |
24 | 24 | 0.369 |
25 | 25 | 0.41 |
26 | 26 | 0.0328 |
27 | 27 | 0.974 |
28 | 28 | 0.494 |
29 | 29 | 0.274 |
3 | 3 | 0.0895 |
30 | 30 | 0.529 |
31 | 31 | 0.743 |
32 | 32 | 0.875 |
33 | 33 | 0.407 |
34 | 34 | 0.471 |
35 | 35 | 0.132 |
36 | 36 | 0.148 |
37 | 37 | 0.0717 |
38 | 38 | 0.331 |
39 | 39 | 0.682 |
4 | 4 | 0.851 |
40 | 40 | 0.184 |
41 | 41 | 0.0124 |
42 | 42 | 0.375 |
43 | 43 | 0.0332 |
44 | 44 | 0.757 |
45 | 45 | 0.698 |
46 | 46 | 0.118 |
47 | 47 | 0.456 |
48 | 48 | 0.398 |
49 | 49 | 0.0917 |
5 | 5 | 0.234 |
50 | 50 | 0.992 |
51 | 51 | 0.333 |
52 | 52 | 0.29 |
53 | 53 | 0.361 |
54 | 54 | 0.295 |
55 | 55 | 0.482 |
56 | 56 | 0.647 |
57 | 57 | 0.751 |
58 | 58 | 0.135 |
59 | 59 | 0.107 |
6 | 6 | 0.514 |
60 | 60 | 0.0379 |
61 | 61 | 0.49 |
62 | 62 | 0.049 |
63 | 63 | 0.434 |
64 | 64 | 0.396 |
65 | 65 | 0.184 |
66 | 66 | 0.193 |
67 | 67 | 0.444 |
68 | 68 | 0.639 |
69 | 69 | 0.888 |
7 | 7 | 0.266 |
70 | 70 | 0.0114 |
71 | 71 | 0.0318 |
72 | 72 | 0.251 |
73 | 73 | 0.13 |
74 | 74 | 0.101 |
75 | 75 | 0.0846 |
76 | 76 | 0.26 |
77 | 77 | 0.359 |
78 | 78 | 0.0685 |
79 | 79 | 0.0537 |
8 | 8 | 0.287 |
80 | 80 | 0.27 |
81 | 81 | 0.367 |
82 | 82 | 0.0732 |
83 | 83 | 0.26 |
84 | 84 | 0.423 |
85 | 85 | 0.00693 |
86 | 86 | 0.0626 |
87 | 87 | 0.496 |
88 | 88 | 0.614 |
89 | 89 | 0.175 |
9 | 9 | 0.319 |
90 | 90 | 0.0651 |
91 | 91 | 0.283 |
92 | 92 | 0.172 |
93 | 93 | 0.413 |
94 | 94 | 0.0301 |
95 | 95 | 0.31 |
96 | 96 | 0.377 |
97 | 97 | 0.914 |
98 | 98 | 0.127 |
99 | 99 | 0.168 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13472
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011105 human CD14-positive monocytes - treated with Cryptococcus sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0000219 (motile cell)
0000325 (stuff accumulating cell)
0000473 (defensive cell)
0000234 (phagocyte)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0000255 (eukaryotic cell)
0000576 (monocyte)
0000860 (classical monocyte)
0002057 (CD14-positive, CD16-negative classical monocyte)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000625 (experimental infection sample)
0000350 (experimentally modified sample)
0000634 (Cryptococcus treatment sample)
0011105 (human CD14-positive monocytes - treated with Cryptococcus sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
CL:0002057 (CD14-positive, CD16-negative classical monocyte)