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Coexpression cluster:C1673: Difference between revisions

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|full_id=C1673_salivary_Corneal_Keratinocyte_Sebocyte_Small_Bronchial_tongue
|full_id=C1673_salivary_Corneal_Keratinocyte_Sebocyte_Small_Bronchial_tongue
|id=C1673
|id=C1673
|ontology_enrichment_celltype=CL:0002076!2.83e-30!43;CL:0000223!2.58e-21!59;CL:0002251!3.60e-18!21;CL:0002368!4.35e-18!13;CL:0000066!5.51e-18!254;CL:0002159!2.12e-15!13;CL:0000622!2.27e-11!5;CL:0002202!5.64e-11!9;CL:0002632!5.64e-11!9;CL:0000154!2.27e-09!6;CL:0002077!4.18e-09!33;CL:0000076!9.51e-09!62;CL:0000244!1.04e-08!4;CL:0000731!1.04e-08!4;CL:0002328!1.17e-07!3;CL:0002623!1.25e-07!3;CL:0002621!2.70e-07!3;CL:0000068!3.06e-07!3;CL:0000069!3.06e-07!3;CL:0000307!3.06e-07!3;CL:0000377!3.06e-07!3;CL:0002166!5.98e-07!3;CL:0000362!6.19e-07!8
|ontology_enrichment_celltype=CL:0002076!2.34e-36!42;CL:0000223!6.91e-27!58;CL:0002368!3.06e-24!13;CL:0002251!4.09e-18!20;CL:0000066!8.37e-18!253;CL:0002159!7.66e-15!14;CL:0002202!2.69e-13!9;CL:0002632!2.69e-13!9;CL:0000622!8.74e-12!5;CL:0002328!2.06e-11!3;CL:0002623!2.21e-11!3;CL:0002621!8.46e-11!3;CL:0000068!1.22e-10!3;CL:0000069!1.22e-10!3;CL:0000307!1.22e-10!3;CL:0000377!1.22e-10!3;CL:0000154!8.19e-10!6;CL:0000240!1.25e-09!6;CL:0000311!1.25e-09!6;CL:0000079!1.25e-09!6;CL:0000237!1.25e-09!6;CL:0000036!1.25e-09!6;CL:0000357!1.25e-09!6;CL:0000114!1.25e-09!6;CL:0000575!2.34e-08!2;CL:0000076!2.91e-08!63;CL:0000244!3.94e-08!4;CL:0000731!3.94e-08!4;CL:0002327!7.91e-08!4;CL:0000312!5.46e-07!5;CL:0002321!6.90e-07!250
|ontology_enrichment_disease=DOID:1749!4.57e-17!14
|ontology_enrichment_disease=DOID:1749!6.03e-13!14
|ontology_enrichment_uberon=UBERON:0000166!6.47e-21!21;UBERON:0001004!1.63e-19!72;UBERON:0000165!9.77e-19!28;UBERON:0000930!9.77e-19!28;UBERON:0004119!1.07e-18!169;UBERON:0000925!1.07e-18!169;UBERON:0006595!1.07e-18!169;UBERON:0000161!1.98e-17!35;UBERON:0003102!7.19e-13!95;UBERON:0001044!6.13e-12!6;UBERON:0003293!6.13e-12!6;UBERON:0003294!6.13e-12!6;UBERON:0010047!6.13e-12!6;UBERON:0000167!6.13e-12!6;UBERON:0005631!8.01e-12!14;UBERON:0000158!8.01e-12!14;UBERON:0001444!1.24e-11!48;UBERON:0003408!4.04e-11!10;UBERON:0000078!4.46e-11!18;UBERON:0007196!1.86e-10!14;UBERON:0001558!1.86e-10!14;UBERON:0001007!3.15e-10!155;UBERON:0001555!3.15e-10!155;UBERON:0007026!3.15e-10!155;UBERON:0000365!5.98e-10!5;UBERON:0003729!9.46e-10!5;UBERON:0000065!1.02e-09!53;UBERON:0000077!3.19e-09!130;UBERON:0003124!3.96e-09!7;UBERON:0005910!3.29e-08!6;UBERON:0000974!6.12e-08!10;UBERON:0001987!6.66e-08!4;UBERON:0004340!6.66e-08!4;UBERON:0003343!7.05e-08!4;UBERON:0004785!7.05e-08!4;UBERON:0002530!8.07e-08!59;UBERON:0004815!1.17e-07!3;UBERON:0002031!1.17e-07!3;UBERON:0001949!2.70e-07!3;UBERON:0006562!2.74e-07!11;UBERON:0001041!3.38e-07!98;UBERON:0003126!4.03e-07!7;UBERON:0001005!4.03e-07!7;UBERON:0000072!6.66e-07!46;UBERON:0000344!8.24e-07!12;UBERON:0001723!8.55e-07!3;UBERON:0001033!8.55e-07!3;UBERON:0010056!8.55e-07!3
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826,0.12998,0.123097,0.254847,0.300809,0.0898207,0.126545,0.0918749,0.0686325,0.0569043,0.0639461,0.387306,0.267408,0.312064,0.080156,0.274185,0.0433679,0.0545112,0.510703,0.33844,0.0649137,0.0974216,0.0137454,0.195675,0.174786,0.176557,0.396547,0.0472148,0.735114,0.229138,0.0639045,0.141461,0.0900204,0.228387,0.385962,0.334921,0.296227,0.208788,0.566117,0.36304,0.430936,0.123626,0.270619,0.132705,0.285556,0.493429,0.233835,0.224471,0.262929,0.223204,0.143824,0.127678,0.431098,0.0775891,0.153079,0.62577,0.211515,0.125701,0.175283,0.204954,0.0236242,0.576888,0.261552,0.084895,0.0135632,0.0819954,0.10091,0.122658,0.151161,0.228398,0.056055,0.120552,0.41771,0.893893,0.830533,0.0637856,0.111864,0.0194612,0.299739,0.278645,0.148202,0.0940982,0.0780533,0.564811,0.0993772,0.274769,0.448923,0.11602,0.344528,0.113233,0.0585992,8.73122e-05,0.0416714,0.911136,0.943187,0.319826,0.0643195,0.173868,0.109708,0.174594,0.0809806,0.154589,0.318794,0.122767,0.0749261,0.176858,0.114361,0.347759,0.242462,0.0620267,0.211111,0.0738743,0.0882327,0.183058,0.150073,0.270522,0.16872,0.341388,0.0934526,0.0739908,0.123404,0.430769,0.240825,0.3033,0.336623,0.163542,0.483244,0.27134,0.154031,0.0313367,0.10226,0.29809,0.235147,0.689826,0.0330886,0.116923,0.148426,0.0983658,0.0284215,0.238223,0.156976,0.0327573,0.267391,0.301441,0.21807,0.350528,0.0850129,0.432408,0.190404,0.135865,0.488841,0.18137,0.180609,0.0472724,0.273972,0.153023,0.0152397,0.0834173,0.22307,0.160699,0.391307,0.166736,0.181253,0.0422294,0.263877,0.146486,0.183121,0.262486,0.0482841,0.131936,0.288826,0.246621,0.0254386,0.119485,0.0965376,0.0822869,0.279263,0.00849138,0.35463,0.581771,0.800557,0.0594155,0.222245,0.208795,0.0713793,0.00190502,0.594469,0.0429502,0.629713,0.0583216,0.355154,0.377285,0.251388,0.180545,0.236988,0.261576,0.306963,0.0538109,0.526495,0.580285,0.550495,0.764863,0.513029,0.610475,0.629179,0.561689,0.306829,0.685628,0.623136,0.349408,0.96913,0.0590455,0.349068,0.344004,0.217481,0.196345,0.108354,0.689998,0.0469865,0.371114,0.111685,0.258394,0.277222,0.432123,0.759415,0.661773,0.494975,0.0903515,0.392155,0.626931,0.371758,0.91821,0.562417,0.64845,0.85279,0.254547,0.673352,0.51445,0.680843,0.931136,0.541378,0.922893,0.29416,0.723387,0.401389,0.705225,0.315485,0.311289,0.318577,0.120474,0.389888,0.603509,0.511254,0.553178,0.246387,0.224252,0.22199,0.155054,0.131605,0.518234,0.257848,0.353942,0.192234,0.000282574,0.0512135,0.131598,0.283682,0.10662,0.919825,0.474058,0.218352,0.341421,0.477016,0.0349115,0.498956,0.209091,0.55798,0.708394,0.932831,0.139363,0.34194,0.226858,0.592314,0.0869207,0.0254154,0.423117,0.0567843,0.265627,0.220564,0.556368,0.262394,0.307462,0.135076,0.469588,0.298027,0.274593,0.490712,0.541363,0.350314,0.218812,0.176255,0.364391,0.562305,0.528646,0.361524,0.31558,0.412744,0.54408,0.259136,0.513592,0.415367,0.815658,0.124718,0.36864,0.538745,0.125335,0.453004,0.0289228,0.557093,0.330982,0.0130321,0.553161,0.0841037,0.0313098,0.339393,0.694478,0.0525779,0.298354,0.0214465,0.784543,0.457741,0.0206327,0.0189513,0.401917,0.0931042,0.572661,0.412586,0.534679,0.41502,0.55475,0.294859,0.0394248,0.499347,0.00628815,0.790204,0.049727,0.0310988,0.714189,0.119992,0.0897597,0.0571105,0.276338,0.126433,0.417412,0.318174,0.0555558,0.295666,0.00174232,0.0480884,0.116969,0.0941346,0.0359836,0.297663,0.256708,0.0650385,0.322052,0.145568,0.153833,0.261242,0.38389,0.54721,0.00164979,0.321362,0.627637,0.280757,0.301366,0.340343,0.343265,0.00566245,0.000457423,0.336254,0.308589,0.291523,0.19697,0.0538978,0.0537285,0.15063,0.198077,0.281455,0.00956309,0.104001,0.138495,0.208834,0.0587417,0.377566,0.342366,0.109684,0.322704,0.403482,0.181288,0.230841,0.352328,0.255358,0.351665,0.0387391,0.0633313,0.10772,0.0854747,0.0747609,0.406458,0.312881,0.00088495,0.244656,0.192188,0.158985,0.174153,0.0972854,0.00822058,0.249919,0.0655592,0.0516568,0.198326,0.394084,0.458518,0.282501,0.252005,0.0889203,0.238377,0.334983,0.197875,0.287909,0.289389,0.117618,0.392533,1.08084e-06,0.0562195,0.330317,0.000691958,0.225079,0.300542,0.379651,0.185715,0.345505,0.000130543,0.271405,0.311201,0.221943,0.306427,0.0114324,0.246925,0.208775,0.390438,0.343014,0.270094,0.0424726,0.156279,0.055329,0.128336,0.422872,0.00848325,0.13327,0.313545,0.17149,0.0877361,0.0880065,0.238969,0.126615,0.0669467,0.0879453,0.136111,0.396935,0.326779,0.0478203,0.358198,0.29552,0.131776,0.158116,0.104606,0.194814,0.104167,0.168186,0.108081,0.123829,0.205215,0.175247,0.0724304,0.109077,0.144842,0.0604892,0.214671,0.316879,0.442567,0.109896,0.00605341,0.224871,0.398887,0.389061,0.310732,0.00964357,0.0221952,0.385709,0.0045314,0.426488,0.400591,0.209809,0.253154,0.319519,0.309489,0.430805,0.362154,0.140472,0.185476,0.00847033,0.344469,0.184651,0.303359,0.0494743,0.42392,0.425912,0.380826,0.259046,0.345068,0.151046,0.0047298,0.0687784,0.321735,0.0126239,0.13907,0.470121,0.0400826,0.250466,0.0165533,0.115686,0.0164276,0.162633,0.0090162,0.27567,0.0337021,0.33299,0.0133264,0.319112,0.172492
}}
}}

Revision as of 11:34, 19 October 2012


Full id: C1673_salivary_Corneal_Keratinocyte_Sebocyte_Small_Bronchial_tongue



Phase1 CAGE Peaks

Hg19::chr12:52908631..52908640,-p@chr12:52908631..52908640
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Hg19::chr12:52908986..52908996,-p@chr12:52908986..52908996
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Hg19::chr12:52909007..52909012,-p@chr12:52909007..52909012
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Hg19::chr17:39740615..39740628,-p7@KRT14
Hg19::chr17:39741249..39741272,-p@chr17:39741249..39741272
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen
endo-epithelial cell2.34e-3642
endodermal cell6.91e-2758
respiratory epithelial cell3.06e-2413
epithelial cell of alimentary canal4.09e-1820
epithelial cell8.37e-18253
general ecto-epithelial cell7.66e-1514
epithelial cell of tracheobronchial tree2.69e-139
epithelial cell of lower respiratory tract2.69e-139
acinar cell8.74e-125
bronchial epithelial cell2.06e-113
acinar cell of salivary gland2.21e-113
gingival epithelial cell8.46e-113
duct epithelial cell1.22e-103
branched duct epithelial cell1.22e-103
tracheal epithelial cell1.22e-103
tracheoblast1.22e-103
protein secreting cell8.19e-106
stratified squamous epithelial cell1.25e-096
keratin accumulating cell1.25e-096
stratified epithelial cell1.25e-096
keratinizing barrier epithelial cell1.25e-096
epithelial fate stem cell1.25e-096
stratified epithelial stem cell1.25e-096
surface ectodermal cell1.25e-096
corneal epithelial cell2.34e-082
squamous epithelial cell2.91e-0863
transitional epithelial cell3.94e-084
urothelial cell3.94e-084
mammary gland epithelial cell7.91e-084
keratinocyte5.46e-075
embryonic cell6.90e-07250
Uber Anatomy
Ontology termp-valuen
oral opening2.79e-2222
respiratory system3.04e-2174
mouth6.18e-1929
stomodeum6.18e-1929
orifice8.48e-1736
endoderm-derived structure4.56e-16160
endoderm4.56e-16160
presumptive endoderm4.56e-16160
head1.25e-1456
surface structure1.45e-1499
anterior region of body2.39e-1462
craniocervical region2.39e-1462
subdivision of head1.88e-1349
tracheobronchial tree6.93e-1315
lower respiratory tract6.93e-1315
respiratory tract1.68e-1154
mouth mucosa1.95e-1113
lower respiratory tract epithelium2.06e-113
epithelium of bronchus2.06e-113
trachea3.61e-117
respiratory airway3.61e-117
gingival epithelium8.46e-113
tongue4.57e-103
gustatory system4.57e-103
future tongue4.57e-103
saliva-secreting gland2.15e-096
gland of oral region2.15e-096
gland of foregut2.15e-096
oral gland2.15e-096
oral cavity2.15e-096
mucosa4.71e-0920
digestive system1.41e-08145
digestive tract1.41e-08145
primitive gut1.41e-08145
mammary gland7.91e-084
mammary bud7.91e-084
mammary ridge7.91e-084
mammary placode7.91e-084
foregut8.41e-0887
thoracic cavity element8.66e-0834
thoracic cavity8.66e-0834
mucosa of oral region1.24e-074
respiratory system mucosa1.24e-074
thoracic segment organ1.64e-0735
segment of respiratory tract2.63e-0747
bronchus5.57e-075
open tracheal system trachea8.19e-072
Disease
Ontology termp-valuen
squamous cell carcinoma6.03e-1314


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.