FF:11319-117D5: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005857 | ||
| | |DRA_sample_Accession_RNASeq=sRNA-Seq@SAMD00005857 | ||
| | |accession_numbers=CAGE;DRX008275;DRR009147;DRZ000572;DRZ001957;DRZ011922;DRZ013307 | ||
| | |accession_numbers_RNASeq=sRNA-Seq;DRX037044;DRR041410;DRZ007052 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002384,UBERON:0000033,UBERON:0000479,UBERON:0001007,UBERON:0004121,UBERON:0004119,UBERON:0010314,UBERON:0011216,UBERON:0000475,UBERON:0000061,UBERON:0000465,UBERON:0000481,UBERON:0001444,UBERON:0000477,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0000075,UBERON:0010317,UBERON:0001555,UBERON:0001758,UBERON:0000153,UBERON:0007811,UBERON:0002204,UBERON:0001434,UBERON:0000165,UBERON:0003672,UBERON:0011137,UBERON:0010323,UBERON:0003129 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0002320,CL:0002371,CL:0000255,CL:0000057,CL:0002556 | |||
| | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000057,FF:0000001,FF:0000067 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr6:34204921..34204939,+!p3@HMGA1!2.02!2932.78!HMGA1;;chr1:170632285..170632309,+!p1@PRRX1!1.87!82.70!PRRX1;;chr12:66218255..66218304,+!p3@HMGA2!1.83!170.41!HMGA2;;chr1:170633348..170633399,+!p2@PRRX1!1.76!75.82!PRRX1;;chr14:37131058..37131139,+!p1@PAX9!1.74!53.43!PAX9;;chr14:61116183..61116208,-!p1@SIX1!1.73!192.18!SIX1;;chr16:86544113..86544145,+!p1@FOXF1!1.68!57.18!FOXF1;;chr4:174451370..174451387,-!p1@HAND2!1.67!45.42!HAND2;;chr6:1389789..1389821,+!p1@FOXF2!1.60!52.30!FOXF2;;chr12:66218212..66218244,+!p5@HMGA2!1.57!52.05!HMGA2;;chr12:66218598..66218645,+!p2@HMGA2!1.55!154.65!HMGA2;;chr15:57511609..57511651,+!p2@TCF12!1.51!51.55!TCF12;;chr12:66218183..66218209,+!p4@HMGA2!1.50!57.55!HMGA2;;chr7:19157248..19157268,-!p1@TWIST1!1.46!74.95!TWIST1;;chr4:4861385..4861398,+!p1@MSX1!1.40!70.44!MSX1;;chr20:55204351..55204377,+!p1@TFAP2C!1.34!26.65!TFAP2C;;chr16:86600426..86600441,+!p1@FOXC2!1.32!48.92!FOXC2;;chr2:200322654..200322707,-!p2@SATB2!1.32!29.03!SATB2;;chr1:170633262..170633285,+!p3@PRRX1!1.29!20.89!PRRX1;;chr2:223163706..223163730,-!p1@PAX3!1.26!17.27!PAX3;;chr17:59477233..59477263,+!p1@TBX2!1.24!49.67!TBX2;;chr12:115122318..115122331,-!p2@TBX3!1.24!16.52!TBX3;;chr2:239756671..239756732,+!p1@TWIST2!1.23!50.42!TWIST2;;chr2:45236540..45236577,-!p1@SIX2!1.21!15.26!SIX2;;chr14:37126765..37126799,+!p2@PAX9!1.20!15.01!PAX9;;chr11:65667884..65667895,-!p2@FOSL1!1.17!53.68!FOSL1;;chr10:28034739..28034756,-!p1@MKX!1.16!13.51!MKX;;chr9:96717629..96717644,-!p1@BARX1!1.15!13.26!BARX1;;chr2:102091566..102091581,-!p1@RFX8!1.15!13.14!RFX8;;chr12:66218573..66218596,+!p7@HMGA2!1.08!16.39!HMGA2;;chr1:54204818..54204870,-!p@chr1:54204818..54204870,-!1.07!11.51!GLIS1;;chr19:46801639..46801699,+!p1@HIF3A!1.07!10.64!HIF3A;;chr1:170632250..170632277,+!p7@PRRX1!1.06!10.51!PRRX1;;chr2:5832508..5832524,+!p1@SOX11!1.06!10.51!SOX11;;chr20:42543441..42543497,+!p1@TOX2!1.05!46.17!TOX2;;chr1:170632477..170632506,+!p6@PRRX1!1.05!10.13!PRRX1;;chr9:132427883..132427951,+!p2@PRRX2!1.05!10.13!PRRX2;;chr9:132427972..132428056,+!p1@PRRX2!1.04!13.26!PRRX2;;chr6:10412600..10412637,-!p1@TFAP2A!1.02!16.14!TFAP2A;;chr12:85673977..85674015,+!p1@ALX1!1.01!9.13!ALX1;;chr15:83953397..83953425,-!p1@BNC1!1.00!10.26!BNC1;;chr6:1389824..1389840,+!p3@FOXF2!1.00!9.01!FOXF2;;chr2:239756739..239756755,+!p2@TWIST2!0.99!15.14!TWIST2;;chr12:66218378..66218401,+!p6@HMGA2!0.98!13.39!HMGA2;;chr14:61116168..61116180,-!p2@SIX1!0.98!9.76!SIX1;;chr12:66218420..66218439,+!p12@HMGA2!0.98!8.51!HMGA2;;chr2:19558373..19558392,-!p1@OSR1!0.97!23.15!OSR1;;chr12:66218443..66218461,+!p8@HMGA2!0.97!10.89!HMGA2;;chr11:46299539..46299620,+!p2@CREB3L1!0.95!13.64!CREB3L1;;chr17:41622765..41622821,-!p2@ETV4!0.95!12.14!ETV4;;chr12:115122303..115122314,-!p6@TBX3!0.95!8.01!TBX3;;chr1:170632439..170632465,+!p11@PRRX1!0.95!7.88!PRRX1;;chr12:66218152..66218174,+!p10@HMGA2!0.94!8.38!HMGA2;;chr7:14029283..14029311,-!p1@ETV1!0.93!41.29!ETV1;;chr11:65686732..65686756,+!p2@DRAP1!0.92!32.28!DRAP1;;chr6:10415276..10415341,-!p2@TFAP2A!0.92!9.13!TFAP2A;;chr4:174450089..174450153,-!p2@HAND2!0.92!7.26!HAND2;;chr4:299227..299272,-!p1@ZNF732!0.91!7.13!ZNF732;;chr11:46299199..46299233,+!p1@CREB3L1!0.90!37.16!CREB3L1;;chr11:65667846..65667868,-!p1@FOSL1!0.89!188.30!FOSL1;;chr5:321810..321877,+!p1@AHRR!0.89!22.40!AHRR;;chr17:59477197..59477212,+!p2@TBX2!0.89!11.89!TBX2;;chr17:41623009..41623053,-!p4@ETV4!0.89!11.26!ETV4;;chr8:60031682..60031710,-!p2@TOX!0.89!11.14!TOX;;chr20:42543506..42543549,+!p2@TOX2!0.88!16.52!TOX2;;chr2:200323414..200323455,-!p1@SATB2!0.88!14.76!SATB2;;chr12:2986206..2986258,-!p2@FOXM1!0.87!41.16!FOXM1;;chr11:65686802..65686818,+!p6@DRAP1!0.86!11.14!DRAP1;;chr6:45296048..45296082,+!p1@RUNX2!0.86!7.26!RUNX2;;chr1:170632137..170632172,+!p10@PRRX1!0.86!6.26!PRRX1;;chr12:2986275..2986363,-!p1@FOXM1!0.85!65.44!FOXM1;;chr5:176738887..176738934,-!p1@MXD3!0.84!41.91!MXD3;;chr17:41623692..41623715,-!p1@ETV4!0.84!27.15!ETV4;;chr1:170632310..170632321,+!p15@PRRX1!0.84!5.88!PRRX1;;chr1:170632723..170632739,+!p8@PRRX1!0.84!5.88!PRRX1;;chr17:41277372..41277418,-!p1@BRCA1!0.83!22.40!BRCA1;;chr4:26322267..26322334,+!p3@RBPJ!0.83!14.51!RBPJ;;chr17:59477275..59477286,+!p3@TBX2!0.83!7.88!TBX2;;chr14:37126814..37126834,+!p4@PAX9!0.83!5.76!PAX9;;chr6:34204973..34204990,+!p4@HMGA1!0.82!80.08!HMGA1;;chr1:170632115..170632136,+!p9@PRRX1!0.82!5.63!PRRX1;;chr5:134369905..134369972,-!p1@PITX1!0.81!8.63!PITX1;;chr9:77112244..77112262,+!p1@RORB!0.81!6.13!RORB;;chr6:34204672..34204692,+!p1@HMGA1!0.80!643.99!HMGA1;;chr8:60031619..60031676,-!p1@TOX!0.80!12.14!TOX;;chr7:96654133..96654150,-!p1@DLX5!0.80!5.38!DLX5;;chr8:93074803..93074845,-!p1@RUNX1T1!0.80!5.38!RUNX1T1;;chr4:174451350..174451363,-!p3@HAND2!0.80!5.38!HAND2;;chr7:19157043..19157088,-!p2@TWIST1!0.79!13.89!TWIST1;;chr16:86600870..86600921,+!p2@FOXC2!0.79!5.13!FOXC2;;chr12:66218836..66218888,+!p1@HMGA2!0.78!51.42!HMGA2;;chr15:57511589..57511608,+!p4@TCF12!0.78!5.00!TCF12;;chr7:44143925..44143970,+!p1@AEBP1!0.77!120.24!AEBP1;;chr12:115121962..115121987,-!p1@TBX3!0.77!44.92!TBX3;;chr6:45390025..45390076,+!p2@RUNX2!0.76!12.14!RUNX2;;chr8:93074848..93074871,-!p3@RUNX1T1!0.76!4.75!RUNX1T1;;chr7:14029312..14029325,-!p4@ETV1!0.75!5.88!ETV1;;chr12:85673868..85673881,+!p2@ALX1!0.75!4.63!ALX1;;chr2:105470562..105470582,+!p@chr2:105470562..105470582,+!0.75!4.63!POU3F3;;chr2:121493425..121493474,+!p1@GLI2!0.74!10.51!GLI2;;chr17:17726907..17726958,-!p2@SREBF1!0.73!30.15!SREBF1;;chr9:102584262..102584276,+!p1@NR4A3!0.73!10.51!NR4A3;;chr17:41622731..41622764,-!p5@ETV4!0.73!4.38!ETV4;;chr2:95963052..95963106,+!p1@KCNIP3!0.73!4.38!KCNIP3;;chr5:158526917..158526932,-!p1@EBF1!0.72!11.51!EBF1;;chr12:66218003..66218018,+!p9@HMGA2!0.72!5.38!HMGA2;;chr6:31126291..31126399,+!p1@TCF19!0.71!44.29!TCF19;;chr3:12329358..12329393,+!p3@PPARG!0.71!11.01!PPARG;;chr1:170632959..170632987,+!p4@PRRX1!0.71!4.63!PRRX1;;chr12:66358080..66358094,+!p15@HMGA2!0.71!4.13!HMGA2;;chr5:72744594..72744609,-!p1@FOXD1!0.70!20.64!FOXD1;;chr18:22932080..22932170,-!p1@ZNF521!0.70!19.14!ZNF521;;chr8:60031809..60031835,-!p4@TOX!0.70!5.25!TOX;;chr18:52969844..52969895,-!p27@TCF4!0.70!4.00!TCF4;;chr2:172949484..172949522,+!p1@DLX1!0.70!4.00!DLX1;;chr9:102584159..102584174,+!p2@NR4A3!0.69!7.51!NR4A3;;chr12:85674018..85674039,+!p3@ALX1!0.69!3.88!ALX1;;chr12:115121770..115121781,-!p4@TBX3!0.67!3.63!TBX3;;chr5:134369879..134369898,-!p2@PITX1!0.67!3.63!PITX1;;chr20:42295713..42295738,+!p2@MYBL2!0.66!24.52!MYBL2;;chrX:66763856..66763896,+!p1@AR!0.66!5.51!AR;;chr8:67525473..67525518,-!p1@MYBL1!0.65!8.76!MYBL1;;chr9:16870710..16870763,-!p1@BNC2!0.65!6.51!BNC2;;chrX:66763815..66763854,+!p2@AR!0.65!4.75!AR;;chr12:115122005..115122016,-!p3@TBX3!0.65!4.25!TBX3;;chr12:115122262..115122271,-!p7@TBX3!0.65!3.50!TBX3;;chr12:66357214..66357233,+!p13@HMGA2!0.65!3.50!HMGA2;;chr19:57352087..57352102,-!p1@PEG3,p1@ZIM2!0.65!3.50!PEG3;;chr1:170632762..170632786,+!p13@PRRX1!0.65!3.50!PRRX1;;chr2:102091144..102091183,-!p2@RFX8!0.65!3.50!RFX8;;chr2:45236579..45236596,-!p2@SIX2!0.65!3.50!SIX2;;chr2:96012397..96012417,+!p3@KCNIP3!0.65!3.50!KCNIP3;;chr12:96588143..96588185,+!p1@ELK3!0.64!48.30!ELK3;;chr11:113930291..113930339,+!p2@ZBTB16!0.64!6.01!ZBTB16;;chr7:14028488..14028516,-!p2@ETV1!0.64!3.75!ETV1;;chr8:25902876..25902936,-!p1@EBF2!0.64!3.38!EBF2;;chr12:66218469..66218477,+!p16@HMGA2!0.64!3.38!HMGA2;;chr1:47779762..47779827,-!p1@STIL,p1@TAL1!0.63!17.14!TAL1;;chr4:26322419..26322479,+!p2@RBPJ!0.62!46.04!RBPJ;;chr6:85474299..85474324,-!p1@TBX18!0.62!6.26!TBX18;;chr1:170633245..170633256,+!p14@PRRX1!0.62!3.13!PRRX1;;chr14:55493763..55493824,-!p1@WDHD1!0.61!27.40!WDHD1;;chr20:31350184..31350200,+!p1@DNMT3B!0.61!7.26!DNMT3B;;chr19:13134772..13134822,+!p2@NFIX!0.61!4.88!NFIX;;chr17:41622925..41622976,-!p3@ETV4!0.60!4.88!ETV4;;chr16:86600458..86600461,+!p3@FOXC2!0.60!3.00!FOXC2;;chr16:86612320..86612394,+!p1@FOXL1!0.60!3.00!FOXL1;;chr8:60031840..60031869,-!p5@TOX!0.60!3.00!TOX;;chr20:55205825..55205847,+!p2@TFAP2C!0.60!3.00!TFAP2C;;chr11:44331576..44331650,-!p1@ALX4!0.60!3.00!ALX4;;chr7:42276787..42276815,-!p1@GLI3!0.59!8.88!GLI3;;chr1:75600067..75600094,+!p2@LHX8!0.59!2.88!LHX8;;chr8:49833978..49833996,-!p1@SNAI2!0.58!70.44!SNAI2;;chr8:77593474..77593612,+!p1@ZFHX4!0.58!14.01!ZFHX4;;chr8:60031762..60031803,-!p3@TOX!0.58!4.38!TOX;;chr6:20402102..20402152,+!p1@E2F3!0.57!13.26!E2F3;;chr5:150284532..150284549,-!p1@ZNF300!0.57!6.51!ZNF300;;chr1:247171347..247171366,-!p2@ZNF695!0.57!5.63!ZNF695;;chr1:110613276..110613299,-!p2@ALX3!0.57!2.75!ALX3;;chr1:75602043..75602093,+!p1@LHX8!0.57!2.75!LHX8;;chr18:52969674..52969685,-!p24@TCF4!0.57!2.75!TCF4;;chr8:116673894..116673913,-!p12@TRPS1!0.57!2.75!TRPS1;;chr7:42276822..42276895,-!p2@GLI3!0.56!9.38!GLI3;;chr1:61547894..61547968,+!p2@NFIA!0.56!9.01!NFIA;;chr3:157823517..157823562,-!p1@SHOX2!0.56!2.88!SHOX2;;chr2:5832493..5832507,+!p2@SOX11!0.56!2.63!SOX11;;chr19:57352109..57352153,-!p2@ZIM2!0.56!2.63!ZIM2;;chr20:42602000..42602034,+!p5@TOX2!0.56!2.63!TOX2;;chr6:1389871..1389876,+!p4@FOXF2!0.56!2.63!FOXF2;;chr7:96654026..96654061,-!p2@DLX5!0.56!2.63!DLX5;;chr8:60031934..60031986,-!p6@TOX!0.56!2.63!TOX;;chr4:1873100..1873152,+!p1@WHSC1!0.55!24.15!WHSC1;;chr21:47063625..47063658,+!p1@PCBP3!0.55!13.76!PCBP3;;chr7:44143978..44143989,+!p2@AEBP1!0.55!5.25!AEBP1;;chr6:45390002..45390023,+!p6@RUNX2!0.55!4.88!RUNX2;;chr3:141121847..141121868,+!p5@ZBTB38!0.55!4.25!ZBTB38;;chr19:10305581..10305646,-!p1@DNMT1!0.54!109.60!DNMT1;;chr6:35464817..35464894,-!p1@TEAD3!0.54!47.92!TEAD3;;chr19:23433144..23433204,-!p1@ZNF724P!0.54!13.51!ZNF724P;;chr5:178368186..178368238,+!p1@ZNF454!0.54!5.00!ZNF454;;chr5:72744445..72744466,-!p2@FOXD1!0.54!4.63!FOXD1;;chr17:41622834..41622883,-!p6@ETV4!0.54!3.13!ETV4;;chr1:170632051..170632081,+!p16@PRRX1!0.54!2.50!PRRX1;;chr1:170632647..170632659,+!p17@PRRX1!0.54!2.50!PRRX1;;chr1:170633058..170633084,+!p5@PRRX1!0.54!2.50!PRRX1;;chr2:172950227..172950249,+!p2@DLX1!0.54!2.50!DLX1;;chr19:3366570..3366619,+!p1@NFIC!0.53!98.09!NFIC;;chr7:148581360..148581425,-!p1@EZ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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000057;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0002556;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0000075;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0000165;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0001007;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0010323;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0011137 | |||
|ffid_belonging_in_development=CL:0000134 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 43: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Periodontal%2520Ligament%252c%2520donor2.CNhs11962.11319-117D5.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Periodontal%2520Ligament%252c%2520donor2.CNhs11962.11319-117D5.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Periodontal%2520Ligament%252c%2520donor2.CNhs11962.11319-117D5.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Periodontal%2520Ligament%252c%2520donor2.CNhs11962.11319-117D5.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Periodontal%2520Ligament%252c%2520donor2.CNhs11962.11319-117D5.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11319-117D5 | |||
|is_a=EFO:0002091;;FF:0000067 | |||
|is_obsolete= | |||
|library_id=CNhs11962 | |||
|library_id_phase_based=2:CNhs11962 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11319 | |||
|microRNAs_nonnovel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer/#/human#srna;sample;SRhi10004.AGTTCC.11319 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11319 | |||
|microRNAs_novel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer_novel/#/human#srna;sample;SRhi10004.AGTTCC.11319 | |||
|name=Fibroblast - Periodontal Ligament, donor2 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11962,LSID836,release011,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=SRhi10004,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=117 | |||
|rna_catalog_number=SC2635 | |||
|rna_concentration=0.665 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-isopropanol-v1.0 | |||
|rna_lot_number=1847 | |||
|rna_od260/230= | |||
|rna_od260/280= | |||
|rna_position=D5 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=117D5 | |||
|rna_weight_ug=10 | |||
|rnaseq_library_id=SRhi10004.AGTTCC | |||
|sample_age=fetal | |||
|sample_category=primary cells | |||
|sample_cell_catalog=N/A | |||
|sample_cell_line= | |||
|sample_cell_lot=N/A | |||
|sample_cell_type=fibroblast | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=Sciencell/3H | |||
|sample_description= | |||
|sample_dev_stage=fetus | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.30714214882084e-288!GO:0043226;organelle;4.06932740219762e-237!GO:0043229;intracellular organelle;7.26946487626488e-237!GO:0043231;intracellular membrane-bound organelle;1.11316858472462e-228!GO:0043227;membrane-bound organelle;1.88282554268671e-228!GO:0005737;cytoplasm;9.4642736845912e-188!GO:0044422;organelle part;2.1199286804586e-171!GO:0044446;intracellular organelle part;7.98772865028374e-170!GO:0044444;cytoplasmic part;5.95521306534994e-127!GO:0032991;macromolecular complex;2.97519487907435e-115!GO:0005634;nucleus;8.38711797863542e-114!GO:0044238;primary metabolic process;1.85302334881107e-105!GO:0044237;cellular metabolic process;1.78973645341611e-104!GO:0043170;macromolecule metabolic process;2.71251917188462e-99!GO:0030529;ribonucleoprotein complex;3.5254846575473e-92!GO:0044428;nuclear part;1.06972089852812e-91!GO:0043233;organelle lumen;8.14567723757612e-84!GO:0031974;membrane-enclosed lumen;8.14567723757612e-84!GO:0005515;protein binding;3.45965496684103e-79!GO:0003723;RNA binding;2.79186384242144e-75!GO:0005739;mitochondrion;4.35635092000935e-67!GO:0043283;biopolymer metabolic process;9.37110368820561e-65!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.28987162864308e-60!GO:0043234;protein complex;1.25514664409464e-59!GO:0016043;cellular component organization and biogenesis;1.80399025914061e-59!GO:0010467;gene expression;1.70034789980911e-54!GO:0006396;RNA processing;1.70037288292004e-54!GO:0005840;ribosome;3.74801875760974e-53!GO:0031981;nuclear lumen;1.13853091194997e-52!GO:0043228;non-membrane-bound organelle;7.5930839785326e-52!GO:0043232;intracellular non-membrane-bound organelle;7.5930839785326e-52!GO:0006412;translation;2.54779204998514e-48!GO:0031090;organelle membrane;1.12273622234646e-47!GO:0019538;protein metabolic process;1.20562977888985e-46!GO:0006996;organelle organization and biogenesis;1.92892417548787e-45!GO:0006259;DNA metabolic process;2.21873413884297e-45!GO:0044429;mitochondrial part;3.26208807628202e-45!GO:0003735;structural constituent of ribosome;3.89965544676286e-45!GO:0031967;organelle envelope;2.87239682240465e-44!GO:0031975;envelope;6.00642355931836e-44!GO:0016071;mRNA metabolic process;1.09845320483672e-43!GO:0033036;macromolecule localization;6.64942181828922e-42!GO:0015031;protein transport;1.14487671845541e-41!GO:0044260;cellular macromolecule metabolic process;1.65553437453858e-41!GO:0044267;cellular protein metabolic process;7.3375469698944e-41!GO:0008380;RNA splicing;7.67710177779469e-41!GO:0009058;biosynthetic process;1.24405515180179e-39!GO:0033279;ribosomal subunit;1.76499895428588e-38!GO:0003676;nucleic acid binding;2.64369388998379e-38!GO:0065003;macromolecular complex assembly;4.26030851565499e-38!GO:0008104;protein localization;7.65060121477154e-38!GO:0045184;establishment of protein localization;1.08386603056654e-37!GO:0007049;cell cycle;1.10785514778554e-37!GO:0006397;mRNA processing;2.16212252177354e-37!GO:0046907;intracellular transport;2.52186425773936e-37!GO:0044249;cellular biosynthetic process;7.52501867211218e-37!GO:0005829;cytosol;2.11169833347954e-36!GO:0009059;macromolecule biosynthetic process;4.26980237505706e-36!GO:0022607;cellular component assembly;2.63430212582045e-35!GO:0005654;nucleoplasm;3.82415347163783e-34!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.4271239345893e-32!GO:0006886;intracellular protein transport;9.55151211405216e-30!GO:0000166;nucleotide binding;1.30818900149081e-29!GO:0000278;mitotic cell cycle;2.23282503949316e-29!GO:0005694;chromosome;2.7496456117333e-29!GO:0022402;cell cycle process;3.15011461213592e-29!GO:0005681;spliceosome;4.25981892903986e-29!GO:0005740;mitochondrial envelope;2.11024769582054e-28!GO:0005830;cytosolic ribosome (sensu Eukaryota);6.16930614257183e-28!GO:0016070;RNA metabolic process;6.55909821813834e-28!GO:0044451;nucleoplasm part;1.85032881791171e-27!GO:0031966;mitochondrial membrane;2.1534687681046e-26!GO:0019866;organelle inner membrane;5.19117438984185e-26!GO:0044427;chromosomal part;5.21141261568179e-26!GO:0006974;response to DNA damage stimulus;1.02723376112774e-24!GO:0022403;cell cycle phase;2.21266758611191e-24!GO:0000087;M phase of mitotic cell cycle;2.42057108849492e-24!GO:0007067;mitosis;6.70500360599194e-24!GO:0005743;mitochondrial inner membrane;9.78785417908806e-24!GO:0051649;establishment of cellular localization;1.31631027252556e-23!GO:0051641;cellular localization;1.47568230662614e-23!GO:0016462;pyrophosphatase activity;8.46277384198627e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.35700711019369e-22!GO:0051276;chromosome organization and biogenesis;1.79521021062945e-22!GO:0016817;hydrolase activity, acting on acid anhydrides;2.31218810386706e-22!GO:0017111;nucleoside-triphosphatase activity;4.68916216481107e-22!GO:0044445;cytosolic part;6.52463145298188e-22!GO:0051301;cell division;9.72120173850835e-22!GO:0000279;M phase;3.57624073826355e-21!GO:0006281;DNA repair;4.57352704893984e-21!GO:0032553;ribonucleotide binding;1.43731425235093e-20!GO:0032555;purine ribonucleotide binding;1.43731425235093e-20!GO:0031980;mitochondrial lumen;1.61534631789448e-20!GO:0005759;mitochondrial matrix;1.61534631789448e-20!GO:0017076;purine nucleotide binding;1.93683132558096e-20!GO:0012505;endomembrane system;2.07022562461611e-20!GO:0015934;large ribosomal subunit;2.83864178116578e-20!GO:0016874;ligase activity;3.77131940995544e-20!GO:0006119;oxidative phosphorylation;8.02246669973727e-20!GO:0006457;protein folding;9.86600749109363e-20!GO:0015935;small ribosomal subunit;2.80064813537472e-19!GO:0005730;nucleolus;4.95022240787542e-19!GO:0022618;protein-RNA complex assembly;5.83359928320141e-19!GO:0044455;mitochondrial membrane part;6.78656532995455e-19!GO:0006512;ubiquitin cycle;1.59526943864607e-18!GO:0005524;ATP binding;1.59526943864607e-18!GO:0006260;DNA replication;1.60538116730568e-18!GO:0032559;adenyl ribonucleotide binding;4.27780177965281e-18!GO:0009719;response to endogenous stimulus;6.69865073569589e-18!GO:0030554;adenyl nucleotide binding;8.87179826376137e-18!GO:0048770;pigment granule;2.10712893374081e-17!GO:0042470;melanosome;2.10712893374081e-17!GO:0006325;establishment and/or maintenance of chromatin architecture;6.04379826660189e-17!GO:0044265;cellular macromolecule catabolic process;6.2515538846491e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;1.16220395475223e-16!GO:0005635;nuclear envelope;1.26232294216184e-16!GO:0006511;ubiquitin-dependent protein catabolic process;1.5304071658632e-16!GO:0019941;modification-dependent protein catabolic process;1.84646553290567e-16!GO:0043632;modification-dependent macromolecule catabolic process;1.84646553290567e-16!GO:0043285;biopolymer catabolic process;2.45586947644189e-16!GO:0006323;DNA packaging;3.15486262507219e-16!GO:0008134;transcription factor binding;3.80920129161588e-16!GO:0044257;cellular protein catabolic process;3.87386967814597e-16!GO:0031965;nuclear membrane;5.68514056633976e-16!GO:0008135;translation factor activity, nucleic acid binding;6.01053076891003e-16!GO:0005746;mitochondrial respiratory chain;1.19983770922524e-15!GO:0044453;nuclear membrane part;1.31946941410568e-15!GO:0006605;protein targeting;1.42856756139842e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.59260002677741e-15!GO:0005783;endoplasmic reticulum;3.07995076785517e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;3.81674665389905e-15!GO:0000375;RNA splicing, via transesterification reactions;3.81674665389905e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;3.81674665389905e-15!GO:0005761;mitochondrial ribosome;3.90259249964875e-15!GO:0000313;organellar ribosome;3.90259249964875e-15!GO:0051186;cofactor metabolic process;5.1921820432832e-15!GO:0000502;proteasome complex (sensu Eukaryota);5.1921820432832e-15!GO:0009057;macromolecule catabolic process;1.09583574075261e-14!GO:0042254;ribosome biogenesis and assembly;2.48536584548173e-14!GO:0050136;NADH dehydrogenase (quinone) activity;2.9821176824199e-14!GO:0003954;NADH dehydrogenase activity;2.9821176824199e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.9821176824199e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);3.58023585176275e-14!GO:0043412;biopolymer modification;4.74930881966636e-14!GO:0030163;protein catabolic process;4.98714398474778e-14!GO:0005794;Golgi apparatus;5.91707421489275e-14!GO:0016604;nuclear body;6.70928283715803e-14!GO:0000785;chromatin;7.6561900852141e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);7.68439465490633e-14!GO:0044432;endoplasmic reticulum part;8.74526146204969e-14!GO:0048193;Golgi vesicle transport;1.29240936347243e-13!GO:0065004;protein-DNA complex assembly;1.4392129105643e-13!GO:0006333;chromatin assembly or disassembly;1.85482149056548e-13!GO:0044248;cellular catabolic process;2.8789449880257e-13!GO:0015630;microtubule cytoskeleton;3.78947967469456e-13!GO:0005643;nuclear pore;4.54883803434954e-13!GO:0051726;regulation of cell cycle;7.39643957747436e-13!GO:0000074;regulation of progression through cell cycle;9.17564181882723e-13!GO:0042775;organelle ATP synthesis coupled electron transport;1.23536462929851e-12!GO:0042773;ATP synthesis coupled electron transport;1.23536462929851e-12!GO:0051082;unfolded protein binding;1.49845992952535e-12!GO:0003743;translation initiation factor activity;1.55338524035227e-12!GO:0030964;NADH dehydrogenase complex (quinone);2.07161715811113e-12!GO:0045271;respiratory chain complex I;2.07161715811113e-12!GO:0005747;mitochondrial respiratory chain complex I;2.07161715811113e-12!GO:0006913;nucleocytoplasmic transport;3.15699696337419e-12!GO:0006464;protein modification process;3.74764345201237e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;5.01994644169384e-12!GO:0050794;regulation of cellular process;5.85088751635783e-12!GO:0016887;ATPase activity;6.14298513293884e-12!GO:0004386;helicase activity;6.34846290722142e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;7.0496073434551e-12!GO:0006413;translational initiation;7.0496073434551e-12!GO:0051169;nuclear transport;8.19206562478766e-12!GO:0042623;ATPase activity, coupled;1.23367266183137e-11!GO:0006732;coenzyme metabolic process;1.26561956818063e-11!GO:0006403;RNA localization;2.68604008269228e-11!GO:0050657;nucleic acid transport;2.72844773268892e-11!GO:0051236;establishment of RNA localization;2.72844773268892e-11!GO:0050658;RNA transport;2.72844773268892e-11!GO:0005793;ER-Golgi intermediate compartment;3.01927240211718e-11!GO:0006366;transcription from RNA polymerase II promoter;3.41531068781418e-11!GO:0006334;nucleosome assembly;4.80712814750523e-11!GO:0003712;transcription cofactor activity;4.81880365625884e-11!GO:0065002;intracellular protein transport across a membrane;5.00218414691749e-11!GO:0006399;tRNA metabolic process;5.37888063838153e-11!GO:0006446;regulation of translational initiation;6.31940431752823e-11!GO:0016607;nuclear speck;6.43523775793006e-11!GO:0043687;post-translational protein modification;6.58632298206329e-11!GO:0016192;vesicle-mediated transport;7.3854605505627e-11!GO:0000775;chromosome, pericentric region;7.39687522088968e-11!GO:0046930;pore complex;7.69323063555334e-11!GO:0005819;spindle;1.28016689998521e-10!GO:0031497;chromatin assembly;2.46431727378812e-10!GO:0009259;ribonucleotide metabolic process;3.60906621556058e-10!GO:0008565;protein transporter activity;3.86619783321618e-10!GO:0008639;small protein conjugating enzyme activity;3.96420367316518e-10!GO:0006461;protein complex assembly;3.99324746102523e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;4.30489963685727e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;6.1562395817815e-10!GO:0004812;aminoacyl-tRNA ligase activity;6.1562395817815e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;6.1562395817815e-10!GO:0009055;electron carrier activity;6.40040349726707e-10!GO:0006163;purine nucleotide metabolic process;8.42074179896335e-10!GO:0004842;ubiquitin-protein ligase activity;8.71875428344308e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;8.90386182419633e-10!GO:0043038;amino acid activation;1.26355711362573e-09!GO:0006418;tRNA aminoacylation for protein translation;1.26355711362573e-09!GO:0043039;tRNA aminoacylation;1.26355711362573e-09!GO:0043566;structure-specific DNA binding;1.30987977917171e-09!GO:0019787;small conjugating protein ligase activity;1.50686996814216e-09!GO:0006364;rRNA processing;1.55113480973098e-09!GO:0008026;ATP-dependent helicase activity;1.58022905717499e-09!GO:0003697;single-stranded DNA binding;1.69194591277153e-09!GO:0051028;mRNA transport;1.96437006723045e-09!GO:0005789;endoplasmic reticulum membrane;2.33988120590945e-09!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.62578834204576e-09!GO:0005813;centrosome;3.67474480155526e-09!GO:0009150;purine ribonucleotide metabolic process;3.87485572402995e-09!GO:0016072;rRNA metabolic process;5.13964020664565e-09!GO:0017038;protein import;5.32117833977528e-09!GO:0016568;chromatin modification;6.08143940188508e-09!GO:0005815;microtubule organizing center;9.40596798402917e-09!GO:0030532;small nuclear ribonucleoprotein complex;1.02037233576028e-08!GO:0009060;aerobic respiration;1.03641830770188e-08!GO:0016881;acid-amino acid ligase activity;1.06687398534409e-08!GO:0006261;DNA-dependent DNA replication;1.08510325533692e-08!GO:0006164;purine nucleotide biosynthetic process;1.10101981317211e-08!GO:0050789;regulation of biological process;1.2708844859989e-08!GO:0009260;ribonucleotide biosynthetic process;1.3649146557764e-08!GO:0019222;regulation of metabolic process;1.69796655037789e-08!GO:0006888;ER to Golgi vesicle-mediated transport;1.7151744431959e-08!GO:0045333;cellular respiration;2.01544191282953e-08!GO:0012501;programmed cell death;2.01544191282953e-08!GO:0005667;transcription factor complex;2.30685457935355e-08!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.87481366672378e-08!GO:0006915;apoptosis;3.58079107375282e-08!GO:0016740;transferase activity;5.08850130919119e-08!GO:0009152;purine ribonucleotide biosynthetic process;5.1370647757409e-08!GO:0009141;nucleoside triphosphate metabolic process;5.20601291782013e-08!GO:0009199;ribonucleoside triphosphate metabolic process;5.34461993593084e-08!GO:0048523;negative regulation of cellular process;5.39498093682365e-08!GO:0007051;spindle organization and biogenesis;5.39498093682365e-08!GO:0030120;vesicle coat;7.79981098977835e-08!GO:0030662;coated vesicle membrane;7.79981098977835e-08!GO:0051329;interphase of mitotic cell cycle;9.28076989285785e-08!GO:0016779;nucleotidyltransferase activity;1.08549556895169e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.16107683081332e-07!GO:0009144;purine nucleoside triphosphate metabolic process;1.16107683081332e-07!GO:0031324;negative regulation of cellular metabolic process;1.21301513986278e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.39350389411116e-07!GO:0051188;cofactor biosynthetic process;1.40395945613621e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.59429739082387e-07!GO:0048475;coated membrane;1.60146635931084e-07!GO:0030117;membrane coat;1.60146635931084e-07!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.66262634500156e-07!GO:0008219;cell death;1.73937998215475e-07!GO:0016265;death;1.73937998215475e-07!GO:0009056;catabolic process;2.07116153073963e-07!GO:0003924;GTPase activity;2.20991118933334e-07!GO:0007010;cytoskeleton organization and biogenesis;2.28492897065877e-07!GO:0006099;tricarboxylic acid cycle;2.31365783624983e-07!GO:0046356;acetyl-CoA catabolic process;2.31365783624983e-07!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.55726491905155e-07!GO:0008094;DNA-dependent ATPase activity;3.02788488779653e-07!GO:0005657;replication fork;3.02788488779653e-07!GO:0032446;protein modification by small protein conjugation;3.23130082194966e-07!GO:0051325;interphase;3.6254846661774e-07!GO:0000151;ubiquitin ligase complex;4.03041640767327e-07!GO:0006084;acetyl-CoA metabolic process;4.19666033101873e-07!GO:0000245;spliceosome assembly;4.51776735111982e-07!GO:0000075;cell cycle checkpoint;5.63443765494395e-07!GO:0046034;ATP metabolic process;5.84517591241663e-07!GO:0007005;mitochondrion organization and biogenesis;6.22355618241892e-07!GO:0016567;protein ubiquitination;6.63833750833286e-07!GO:0016563;transcription activator activity;6.66094401547551e-07!GO:0009109;coenzyme catabolic process;6.66094401547551e-07!GO:0003713;transcription coactivator activity;7.39700472421845e-07!GO:0051246;regulation of protein metabolic process;7.91142760876742e-07!GO:0015986;ATP synthesis coupled proton transport;9.55549643730392e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;9.55549643730392e-07!GO:0009142;nucleoside triphosphate biosynthetic process;1.02840406560529e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.02840406560529e-06!GO:0051170;nuclear import;1.05397639434055e-06!GO:0044431;Golgi apparatus part;1.07112202224414e-06!GO:0043623;cellular protein complex assembly;1.21171468996087e-06!GO:0005788;endoplasmic reticulum lumen;1.21701098150863e-06!GO:0009892;negative regulation of metabolic process;1.24028663713291e-06!GO:0019829;cation-transporting ATPase activity;1.32048852979577e-06!GO:0051187;cofactor catabolic process;1.57810206317528e-06!GO:0006606;protein import into nucleus;1.66462309660119e-06!GO:0015078;hydrogen ion transmembrane transporter activity;1.66739236561183e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.84202202254561e-06!GO:0016469;proton-transporting two-sector ATPase complex;1.84813843582623e-06!GO:0016481;negative regulation of transcription;1.96334266208919e-06!GO:0007059;chromosome segregation;1.96963447623737e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.17644696842312e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.17644696842312e-06!GO:0048519;negative regulation of biological process;2.24507157205165e-06!GO:0045259;proton-transporting ATP synthase complex;2.5434703349526e-06!GO:0009117;nucleotide metabolic process;2.92235378472799e-06!GO:0003724;RNA helicase activity;3.52169961942999e-06!GO:0005768;endosome;3.56657026166374e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;3.57904525829465e-06!GO:0031323;regulation of cellular metabolic process;4.13085482516751e-06!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;4.69618370557969e-06!GO:0006793;phosphorus metabolic process;5.50242231862063e-06!GO:0006796;phosphate metabolic process;5.50242231862063e-06!GO:0009108;coenzyme biosynthetic process;5.81074464675059e-06!GO:0006613;cotranslational protein targeting to membrane;5.81074464675059e-06!GO:0016564;transcription repressor activity;6.50805387632561e-06!GO:0000776;kinetochore;6.88096504720186e-06!GO:0000786;nucleosome;6.95238436063556e-06!GO:0005762;mitochondrial large ribosomal subunit;8.16202207326128e-06!GO:0000315;organellar large ribosomal subunit;8.16202207326128e-06!GO:0003899;DNA-directed RNA polymerase activity;8.24917622599878e-06!GO:0016859;cis-trans isomerase activity;8.29203837979605e-06!GO:0005798;Golgi-associated vesicle;8.39031689540534e-06!GO:0006350;transcription;8.99733974691129e-06!GO:0006754;ATP biosynthetic process;1.11119666018918e-05!GO:0006753;nucleoside phosphate metabolic process;1.11119666018918e-05!GO:0016853;isomerase activity;1.11171043387471e-05!GO:0003682;chromatin binding;1.14642669352829e-05!GO:0045786;negative regulation of progression through cell cycle;1.2376058739919e-05!GO:0031252;leading edge;1.24499741038322e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;1.41683099268332e-05!GO:0051427;hormone receptor binding;1.50000666271546e-05!GO:0006752;group transfer coenzyme metabolic process;1.80457165050185e-05!GO:0008654;phospholipid biosynthetic process;1.89980544077323e-05!GO:0005874;microtubule;2.23216486279668e-05!GO:0005839;proteasome core complex (sensu Eukaryota);2.23608943851597e-05!GO:0016126;sterol biosynthetic process;2.3738064281612e-05!GO:0019899;enzyme binding;2.60740154748097e-05!GO:0044440;endosomal part;2.60740154748097e-05!GO:0010008;endosome membrane;2.60740154748097e-05!GO:0015980;energy derivation by oxidation of organic compounds;2.75867434852516e-05!GO:0005525;GTP binding;2.9862355215197e-05!GO:0006302;double-strand break repair;3.19790760160329e-05!GO:0000139;Golgi membrane;3.27761525183119e-05!GO:0035257;nuclear hormone receptor binding;3.33184116644806e-05!GO:0016310;phosphorylation;3.39084584195503e-05!GO:0043021;ribonucleoprotein binding;3.86716762165546e-05!GO:0031988;membrane-bound vesicle;4.64232640662632e-05!GO:0006310;DNA recombination;4.77933534784163e-05!GO:0051168;nuclear export;4.78724170124137e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;5.28229398384979e-05!GO:0045454;cell redox homeostasis;5.28229398384979e-05!GO:0030867;rough endoplasmic reticulum membrane;5.55390778158314e-05!GO:0016023;cytoplasmic membrane-bound vesicle;5.58771870608555e-05!GO:0000059;protein import into nucleus, docking;6.65765697177944e-05!GO:0030036;actin cytoskeleton organization and biogenesis;7.10872498803585e-05!GO:0010468;regulation of gene expression;7.34587970848526e-05!GO:0031968;organelle outer membrane;7.6562495134957e-05!GO:0003690;double-stranded DNA binding;8.09969932676626e-05!GO:0003684;damaged DNA binding;8.19436736608632e-05!GO:0019867;outer membrane;8.25625654937364e-05!GO:0051252;regulation of RNA metabolic process;8.73699536232238e-05!GO:0031982;vesicle;8.80949108540301e-05!GO:0016363;nuclear matrix;8.85826827119808e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;9.28859703593336e-05!GO:0051052;regulation of DNA metabolic process;9.70089287015487e-05!GO:0006916;anti-apoptosis;0.000100933063337714!GO:0016787;hydrolase activity;0.000109908269926226!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000114977539362483!GO:0031410;cytoplasmic vesicle;0.000115369902906008!GO:0004298;threonine endopeptidase activity;0.000122177155854486!GO:0000314;organellar small ribosomal subunit;0.000123303605838675!GO:0005763;mitochondrial small ribosomal subunit;0.000123303605838675!GO:0005905;coated pit;0.000128401942241462!GO:0016491;oxidoreductase activity;0.000134025846834548!GO:0007052;mitotic spindle organization and biogenesis;0.00014191846667278!GO:0008186;RNA-dependent ATPase activity;0.000145289784838755!GO:0065007;biological regulation;0.000151449502476671!GO:0006695;cholesterol biosynthetic process;0.000153924777776188!GO:0030133;transport vesicle;0.00017740487937059!GO:0000228;nuclear chromosome;0.000177764184781234!GO:0032561;guanyl ribonucleotide binding;0.000181789365503895!GO:0019001;guanyl nucleotide binding;0.000181789365503895!GO:0007017;microtubule-based process;0.000185053995279267!GO:0005770;late endosome;0.000195847826983582!GO:0007093;mitotic cell cycle checkpoint;0.000213760695521662!GO:0005048;signal sequence binding;0.000221665396056284!GO:0008092;cytoskeletal protein binding;0.00024658512390054!GO:0007088;regulation of mitosis;0.000246600067083926!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.000258297465066695!GO:0030029;actin filament-based process;0.000262482238117961!GO:0005769;early endosome;0.000271498049338177!GO:0042981;regulation of apoptosis;0.000277780803766035!GO:0005741;mitochondrial outer membrane;0.000289764286446425!GO:0008361;regulation of cell size;0.0002905771323261!GO:0043067;regulation of programmed cell death;0.000316193976643928!GO:0003678;DNA helicase activity;0.000323009417319973!GO:0003729;mRNA binding;0.00033402011338161!GO:0003714;transcription corepressor activity;0.000349528094423572!GO:0016049;cell growth;0.000352089840882804!GO:0006383;transcription from RNA polymerase III promoter;0.000369792331365551!GO:0005885;Arp2/3 protein complex;0.000378967105236617!GO:0043069;negative regulation of programmed cell death;0.000407993818579565!GO:0006626;protein targeting to mitochondrion;0.000417141388666442!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000418893026599787!GO:0004004;ATP-dependent RNA helicase activity;0.000429477266368405!GO:0006402;mRNA catabolic process;0.000431695444611637!GO:0006091;generation of precursor metabolites and energy;0.00044191144588525!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.000504666860507605!GO:0043066;negative regulation of apoptosis;0.000505405297945322!GO:0006612;protein targeting to membrane;0.000512436845815846!GO:0008250;oligosaccharyl transferase complex;0.000534208529946636!GO:0000922;spindle pole;0.000545555212398934!GO:0032774;RNA biosynthetic process;0.000547901612306571!GO:0004674;protein serine/threonine kinase activity;0.000571204983771836!GO:0005876;spindle microtubule;0.000627988319516206!GO:0005791;rough endoplasmic reticulum;0.000628777759672414!GO:0043681;protein import into mitochondrion;0.000631838599119718!GO:0003677;DNA binding;0.000631838599119718!GO:0045892;negative regulation of transcription, DNA-dependent;0.00063606977739639!GO:0046474;glycerophospholipid biosynthetic process;0.000636220116648805!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000655241677891965!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000671346027674485!GO:0006414;translational elongation;0.000691873704138886!GO:0016741;transferase activity, transferring one-carbon groups;0.000702742127708882!GO:0006351;transcription, DNA-dependent;0.000711708522070232!GO:0008168;methyltransferase activity;0.00074969525613968!GO:0008610;lipid biosynthetic process;0.000753189867421094!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000816708894131474!GO:0004576;oligosaccharyl transferase activity;0.00082300110405373!GO:0015631;tubulin binding;0.000855404095533274!GO:0043488;regulation of mRNA stability;0.000858365120508243!GO:0043487;regulation of RNA stability;0.000858365120508243!GO:0042802;identical protein binding;0.000870672920676427!GO:0051789;response to protein stimulus;0.000890899994686119!GO:0006986;response to unfolded protein;0.000890899994686119!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000919531689860462!GO:0033116;ER-Golgi intermediate compartment membrane;0.000927998928872973!GO:0006352;transcription initiation;0.000964658353599781!GO:0035258;steroid hormone receptor binding;0.0010141161303215!GO:0030663;COPI coated vesicle membrane;0.00103402184392343!GO:0030126;COPI vesicle coat;0.00103402184392343!GO:0006839;mitochondrial transport;0.00107875594195165!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00110032280252897!GO:0048471;perinuclear region of cytoplasm;0.0011014097421824!GO:0032508;DNA duplex unwinding;0.00111571577765999!GO:0032392;DNA geometric change;0.00111571577765999!GO:0051920;peroxiredoxin activity;0.00111786453550178!GO:0001558;regulation of cell growth;0.00114095311066952!GO:0048500;signal recognition particle;0.00116924037286079!GO:0008047;enzyme activator activity;0.00118060620649579!GO:0005096;GTPase activator activity;0.00119553961433687!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.00119562489229366!GO:0005684;U2-dependent spliceosome;0.0012021809905049!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00120817888110261!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00120817888110261!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00120817888110261!GO:0000082;G1/S transition of mitotic cell cycle;0.00120884410361063!GO:0031072;heat shock protein binding;0.00128385065295934!GO:0006401;RNA catabolic process;0.00135214412145326!GO:0030134;ER to Golgi transport vesicle;0.00140484110584395!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00143148802250767!GO:0018196;peptidyl-asparagine modification;0.00146229682048607!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00146229682048607!GO:0006268;DNA unwinding during replication;0.00149576911322744!GO:0030658;transport vesicle membrane;0.00153387738609722!GO:0004527;exonuclease activity;0.00155270363022339!GO:0009165;nucleotide biosynthetic process;0.00168089035650985!GO:0007006;mitochondrial membrane organization and biogenesis;0.00172682713676198!GO:0030521;androgen receptor signaling pathway;0.00180056979341484!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00181185270734541!GO:0046467;membrane lipid biosynthetic process;0.00183513156776708!GO:0000910;cytokinesis;0.00183532758585255!GO:0008312;7S RNA binding;0.00186874144923336!GO:0019843;rRNA binding;0.00187383241405129!GO:0045449;regulation of transcription;0.00203479246169707!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.00205952405173379!GO:0006891;intra-Golgi vesicle-mediated transport;0.00207176675259651!GO:0030880;RNA polymerase complex;0.00210870932153838!GO:0006275;regulation of DNA replication;0.00221411954271765!GO:0008033;tRNA processing;0.00222353256166142!GO:0005637;nuclear inner membrane;0.00228684548140201!GO:0030127;COPII vesicle coat;0.00229159178153063!GO:0012507;ER to Golgi transport vesicle membrane;0.00229159178153063!GO:0030137;COPI-coated vesicle;0.00241404748940939!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00241404748940939!GO:0000819;sister chromatid segregation;0.00241404748940939!GO:0030027;lamellipodium;0.00243478222339241!GO:0051540;metal cluster binding;0.00246596954976212!GO:0051536;iron-sulfur cluster binding;0.00246596954976212!GO:0000792;heterochromatin;0.00249554519279091!GO:0008180;signalosome;0.002736284124217!GO:0043596;nuclear replication fork;0.00276208381658731!GO:0030132;clathrin coat of coated pit;0.00278064082394073!GO:0006289;nucleotide-excision repair;0.00280519098708878!GO:0000070;mitotic sister chromatid segregation;0.00288416947836569!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00305012510625151!GO:0045047;protein targeting to ER;0.00305012510625151!GO:0031124;mRNA 3'-end processing;0.00319425984554203!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00320190521952186!GO:0044452;nucleolar part;0.0032998159080014!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00333225166361203!GO:0031570;DNA integrity checkpoint;0.00334095421002166!GO:0051287;NAD binding;0.00344303537768764!GO:0006338;chromatin remodeling;0.00345486170624785!GO:0051087;chaperone binding;0.00349846402970493!GO:0030118;clathrin coat;0.00352716669705903!GO:0045941;positive regulation of transcription;0.00370893690412251!GO:0006405;RNA export from nucleus;0.00371871206395072!GO:0043284;biopolymer biosynthetic process;0.0037220319013594!GO:0045893;positive regulation of transcription, DNA-dependent;0.00379144035085137!GO:0017166;vinculin binding;0.00381197290918864!GO:0008139;nuclear localization sequence binding;0.00381688469048467!GO:0006595;polyamine metabolic process;0.00382209898983845!GO:0032984;macromolecular complex disassembly;0.00389261501443175!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00408945573759345!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00429505199514516!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00429505199514516!GO:0000049;tRNA binding;0.00441425019663792!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00443351341163898!GO:0000428;DNA-directed RNA polymerase complex;0.00443351341163898!GO:0006284;base-excision repair;0.00446533804446989!GO:0006611;protein export from nucleus;0.00467153831036662!GO:0030660;Golgi-associated vesicle membrane;0.00492986258669526!GO:0031901;early endosome membrane;0.004935613395911!GO:0050662;coenzyme binding;0.00551907376416695!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00563545435011205!GO:0005856;cytoskeleton;0.00563545435011205!GO:0046489;phosphoinositide biosynthetic process;0.00571491512103088!GO:0016251;general RNA polymerase II transcription factor activity;0.0057475368931129!GO:0000793;condensed chromosome;0.00611253104699762!GO:0003711;transcription elongation regulator activity;0.00653210430944946!GO:0043624;cellular protein complex disassembly;0.00656948131923326!GO:0008022;protein C-terminus binding;0.00658816807412261!GO:0051128;regulation of cellular component organization and biogenesis;0.00685523541443446!GO:0000725;recombinational repair;0.00690702906401349!GO:0000724;double-strand break repair via homologous recombination;0.00690702906401349!GO:0004003;ATP-dependent DNA helicase activity;0.00710859125351485!GO:0043241;protein complex disassembly;0.00728368054134691!GO:0016584;nucleosome positioning;0.00735935216720296!GO:0009112;nucleobase metabolic process;0.00757384795383848!GO:0042770;DNA damage response, signal transduction;0.0078647026175525!GO:0016044;membrane organization and biogenesis;0.00788460319206632!GO:0042393;histone binding;0.00791922336983986!GO:0007264;small GTPase mediated signal transduction;0.00822128905330104!GO:0048522;positive regulation of cellular process;0.00829840378490482!GO:0050681;androgen receptor binding;0.00863408808221371!GO:0005669;transcription factor TFIID complex;0.00884724550110256!GO:0001726;ruffle;0.00902970981673616!GO:0040029;regulation of gene expression, epigenetic;0.00910375872835385!GO:0044454;nuclear chromosome part;0.00928463290038077!GO:0006144;purine base metabolic process;0.00931561772066557!GO:0005832;chaperonin-containing T-complex;0.00932472229267517!GO:0005758;mitochondrial intermembrane space;0.00942758549400945!GO:0031123;RNA 3'-end processing;0.00946624361857775!GO:0051539;4 iron, 4 sulfur cluster binding;0.00950057861940454!GO:0006220;pyrimidine nucleotide metabolic process;0.0095522752927521!GO:0003746;translation elongation factor activity;0.0097111701691654!GO:0000339;RNA cap binding;0.00976213458569356!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00996096727618371!GO:0006270;DNA replication initiation;0.0101920293499862!GO:0030176;integral to endoplasmic reticulum membrane;0.0109882225162279!GO:0043022;ribosome binding;0.0110847853132958!GO:0007050;cell cycle arrest;0.0114631582577577!GO:0016408;C-acyltransferase activity;0.0114787511212939!GO:0043601;nuclear replisome;0.0115642813988707!GO:0030894;replisome;0.0115642813988707!GO:0030041;actin filament polymerization;0.0115642813988707!GO:0019752;carboxylic acid metabolic process;0.0117196981230473!GO:0016407;acetyltransferase activity;0.0120605213263092!GO:0005869;dynactin complex;0.0123078075410268!GO:0006520;amino acid metabolic process;0.0123078075410268!GO:0006082;organic acid metabolic process;0.0123156262808635!GO:0005862;muscle thin filament tropomyosin;0.0125695479571684!GO:0005100;Rho GTPase activator activity;0.0126414909968034!GO:0005773;vacuole;0.0126855343209938!GO:0004177;aminopeptidase activity;0.0127981392340741!GO:0007243;protein kinase cascade;0.0128726620337489!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.012958595982598!GO:0030119;AP-type membrane coat adaptor complex;0.0129906643573553!GO:0030518;steroid hormone receptor signaling pathway;0.013270041716169!GO:0016197;endosome transport;0.0135810540744321!GO:0065009;regulation of a molecular function;0.0136344456751689!GO:0004518;nuclease activity;0.0136788967522357!GO:0000077;DNA damage checkpoint;0.0137150905559459!GO:0048487;beta-tubulin binding;0.0142611438063734!GO:0006355;regulation of transcription, DNA-dependent;0.0143470191597599!GO:0032200;telomere organization and biogenesis;0.0143592849241271!GO:0000723;telomere maintenance;0.0143592849241271!GO:0000152;nuclear ubiquitin ligase complex;0.0144826253352018!GO:0007346;regulation of progression through mitotic cell cycle;0.0147610138447091!GO:0008154;actin polymerization and/or depolymerization;0.0147610138447091!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0148753462301452!GO:0009303;rRNA transcription;0.0150028255310017!GO:0019206;nucleoside kinase activity;0.0151035067850182!GO:0006650;glycerophospholipid metabolic process;0.0158400317789994!GO:0007021;tubulin folding;0.0158593333051286!GO:0046483;heterocycle metabolic process;0.0158593333051286!GO:0006376;mRNA splice site selection;0.0159092250123188!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0159092250123188!GO:0009116;nucleoside metabolic process;0.016243858673098!GO:0008629;induction of apoptosis by intracellular signals;0.0165118371282459!GO:0032259;methylation;0.0169106042540646!GO:0000209;protein polyubiquitination;0.0173749261194618!GO:0006740;NADPH regeneration;0.0174600583474204!GO:0006098;pentose-phosphate shunt;0.0174600583474204!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0178905983274481!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0180563636745738!GO:0000096;sulfur amino acid metabolic process;0.0181266649930813!GO:0031625;ubiquitin protein ligase binding;0.0183631272063558!GO:0006607;NLS-bearing substrate import into nucleus;0.0183631272063558!GO:0017015;regulation of transforming growth factor beta receptor signaling pathway;0.0184112039263143!GO:0016272;prefoldin complex;0.0186438813051915!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0189438527696595!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0189777454904301!GO:0007569;cell aging;0.0190195160776764!GO:0019783;small conjugating protein-specific protease activity;0.0192951711229206!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0194196156684101!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0194733954296382!GO:0015002;heme-copper terminal oxidase activity;0.0194733954296382!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0194733954296382!GO:0004129;cytochrome-c oxidase activity;0.0194733954296382!GO:0033673;negative regulation of kinase activity;0.0194733954296382!GO:0006469;negative regulation of protein kinase activity;0.0194733954296382!GO:0031577;spindle checkpoint;0.0202469653620805!GO:0048037;cofactor binding;0.0203957055557361!GO:0000178;exosome (RNase complex);0.020443114760409!GO:0043189;H4/H2A histone acetyltransferase complex;0.020443114760409!GO:0043414;biopolymer methylation;0.0206241461749636!GO:0031970;organelle envelope lumen;0.0207182825100523!GO:0008276;protein methyltransferase activity;0.0209774604830861!GO:0030131;clathrin adaptor complex;0.021047360290498!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0215176072337258!GO:0004843;ubiquitin-specific protease activity;0.0216242074014736!GO:0008299;isoprenoid biosynthetic process;0.0216400522183917!GO:0000323;lytic vacuole;0.0216400522183917!GO:0005764;lysosome;0.0216400522183917!GO:0031529;ruffle organization and biogenesis;0.0216400522183917!GO:0003702;RNA polymerase II transcription factor activity;0.0216400522183917!GO:0006950;response to stress;0.0216559077187365!GO:0000287;magnesium ion binding;0.021868614679741!GO:0030659;cytoplasmic vesicle membrane;0.0221888262646506!GO:0006541;glutamine metabolic process;0.0221888262646506!GO:0006378;mRNA polyadenylation;0.0224546423863672!GO:0051348;negative regulation of transferase activity;0.0227543150864133!GO:0045045;secretory pathway;0.0229164694070056!GO:0000084;S phase of mitotic cell cycle;0.0232440895176935!GO:0016301;kinase activity;0.0232440895176935!GO:0000781;chromosome, telomeric region;0.0233727027013546!GO:0030496;midbody;0.0233727027013546!GO:0035267;NuA4 histone acetyltransferase complex;0.0236957624874706!GO:0030125;clathrin vesicle coat;0.0240123789926364!GO:0030665;clathrin coated vesicle membrane;0.0240123789926364!GO:0015992;proton transport;0.0245957429596354!GO:0047485;protein N-terminus binding;0.0247340407740163!GO:0051053;negative regulation of DNA metabolic process;0.0247340407740163!GO:0006818;hydrogen transport;0.0262297986903693!GO:0005663;DNA replication factor C complex;0.026462257839709!GO:0009124;nucleoside monophosphate biosynthetic process;0.0265005605528551!GO:0009123;nucleoside monophosphate metabolic process;0.0265005605528551!GO:0006509;membrane protein ectodomain proteolysis;0.0266032777449982!GO:0033619;membrane protein proteolysis;0.0266032777449982!GO:0005083;small GTPase regulator activity;0.0271198335833995!GO:0006497;protein amino acid lipidation;0.0271437501582438!GO:0008632;apoptotic program;0.0274904607442548!GO:0016790;thiolester hydrolase activity;0.0279621430219632!GO:0030695;GTPase regulator activity;0.0282045220666826!GO:0008652;amino acid biosynthetic process;0.0284717499774393!GO:0000123;histone acetyltransferase complex;0.0292271316165876!GO:0031371;ubiquitin conjugating enzyme complex;0.029274738961494!GO:0006984;ER-nuclear signaling pathway;0.0292910017596119!GO:0004221;ubiquitin thiolesterase activity;0.0297144597742343!GO:0022411;cellular component disassembly;0.0298064153504943!GO:0051656;establishment of organelle localization;0.0298924566011!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0299967077222589!GO:0015399;primary active transmembrane transporter activity;0.0299967077222589!GO:0000118;histone deacetylase complex;0.0306050310459689!GO:0004722;protein serine/threonine phosphatase activity;0.0307719607495585!GO:0007265;Ras protein signal transduction;0.0308999654435134!GO:0044262;cellular carbohydrate metabolic process;0.0314714180743469!GO:0003756;protein disulfide isomerase activity;0.0322988328834134!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0322988328834134!GO:0007004;telomere maintenance via telomerase;0.0324288468020798!GO:0008536;Ran GTPase binding;0.0325112655107527!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0325163049089605!GO:0046128;purine ribonucleoside metabolic process;0.0325163049089605!GO:0042278;purine nucleoside metabolic process;0.0325163049089605!GO:0030145;manganese ion binding;0.0326234756437304!GO:0005099;Ras GTPase activator activity;0.0328779177426677!GO:0040008;regulation of growth;0.0330026629496854!GO:0004523;ribonuclease H activity;0.0330026629496854!GO:0006892;post-Golgi vesicle-mediated transport;0.0331305901975798!GO:0005784;translocon complex;0.0340854377969471!GO:0006979;response to oxidative stress;0.0344848186946265!GO:0004448;isocitrate dehydrogenase activity;0.0345953903326544!GO:0051098;regulation of binding;0.0346330806478059!GO:0008234;cysteine-type peptidase activity;0.0349220173628181!GO:0030911;TPR domain binding;0.0352146247439785!GO:0030508;thiol-disulfide exchange intermediate activity;0.0353778079960203!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0354285917066237!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0355097829770964!GO:0006779;porphyrin biosynthetic process;0.0367172252023926!GO:0033014;tetrapyrrole biosynthetic process;0.0367172252023926!GO:0005875;microtubule associated complex;0.0369049956250257!GO:0031902;late endosome membrane;0.0370053360801744!GO:0046112;nucleobase biosynthetic process;0.0374016052297702!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0383337041590226!GO:0042026;protein refolding;0.0383337041590226!GO:0008017;microtubule binding;0.0383337041590226!GO:0006778;porphyrin metabolic process;0.0384447015148716!GO:0033013;tetrapyrrole metabolic process;0.0384447015148716!GO:0051101;regulation of DNA binding;0.0386410685737175!GO:0017134;fibroblast growth factor binding;0.0389206661531711!GO:0008287;protein serine/threonine phosphatase complex;0.0391199675995377!GO:0030384;phosphoinositide metabolic process;0.0394556646680168!GO:0016581;NuRD complex;0.0396736632397163!GO:0008097;5S rRNA binding;0.0397324280622293!GO:0043130;ubiquitin binding;0.040047782966197!GO:0032182;small conjugating protein binding;0.040047782966197!GO:0051320;S phase;0.0400964111931065!GO:0005881;cytoplasmic microtubule;0.0403839497427893!GO:0016125;sterol metabolic process;0.0403839497427893!GO:0003985;acetyl-CoA C-acetyltransferase activity;0.0403839497427893!GO:0022415;viral reproductive process;0.0405301395747373!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0407316268589684!GO:0008286;insulin receptor signaling pathway;0.0408377412344823!GO:0000726;non-recombinational repair;0.0410472032234636!GO:0003887;DNA-directed DNA polymerase activity;0.0414474117667084!GO:0008408;3'-5' exonuclease activity;0.0415313180457489!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0415676966707039!GO:0046966;thyroid hormone receptor binding;0.0419221857644208!GO:0009451;RNA modification;0.0428158058487959!GO:0006739;NADP metabolic process;0.0428650827423483!GO:0005680;anaphase-promoting complex;0.0429620282344086!GO:0006506;GPI anchor biosynthetic process;0.0429620282344086!GO:0044433;cytoplasmic vesicle part;0.0429620282344086!GO:0006730;one-carbon compound metabolic process;0.0430305456353088!GO:0030032;lamellipodium biogenesis;0.0431073601304092!GO:0006007;glucose catabolic process;0.0435180770877086!GO:0004680;casein kinase activity;0.0435180770877086!GO:0030522;intracellular receptor-mediated signaling pathway;0.0435180770877086!GO:0043550;regulation of lipid kinase activity;0.0452906553434116!GO:0050178;phenylpyruvate tautomerase activity;0.0454361563571986!GO:0030833;regulation of actin filament polymerization;0.046184453668401!GO:0051493;regulation of cytoskeleton organization and biogenesis;0.0465793891027262!GO:0033043;regulation of organelle organization and biogenesis;0.0465793891027262!GO:0006596;polyamine biosynthetic process;0.0466060829951848!GO:0016585;chromatin remodeling complex;0.0466939406753178!GO:0012506;vesicle membrane;0.046786593189788!GO:0004532;exoribonuclease activity;0.0470157639598759!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0470157639598759!GO:0003779;actin binding;0.0474998575843667!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0481361917447144!GO:0042158;lipoprotein biosynthetic process;0.0484989291995416!GO:0032153;cell division site;0.0498321574716169!GO:0032155;cell division site part;0.0498321574716169!GO:0006505;GPI anchor metabolic process;0.0499614645770342!GO:0050000;chromosome localization;0.0499614645770342!GO:0051303;establishment of chromosome localization;0.0499614645770342!GO:0004239;methionyl aminopeptidase activity;0.0499614645770342 | |||
|sample_id=11319 | |||
|sample_note= | |||
|sample_sex=unknown | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=periodontal ligament | |||
|top_motifs=TFDP1:1.77608075549;TOPORS:1.5157380392;GFI1:1.41981338001;E2F1..5:1.38507585312;ALX4:1.30409372567;NFY{A,B,C}:1.19689032998;PAX8:1.10197064252;NKX2-2,8:1.06818837438;ZIC1..3:1.05663375165;AIRE:1.03664935076;MYB:0.940038947204;PDX1:0.896639836915;ZNF238:0.835869823999;EN1,2:0.813507164028;FOXD3:0.784660858093;PAX4:0.780982418356;ZNF143:0.773597665991;POU3F1..4:0.734778716458;NR3C1:0.689437289074;NR1H4:0.685048612429;RXR{A,B,G}:0.674166432679;MZF1:0.674070411014;TFAP4:0.659771997513;GZF1:0.654395106532;NRF1:0.609006644214;NKX3-1:0.589446480472;NKX6-1,2:0.586051214085;UFEwm:0.584271398741;TFAP2{A,C}:0.580765347849;SOX17:0.566055678021;GTF2A1,2:0.565399501245;TEF:0.561764581093;XCPE1{core}:0.536162849451;YY1:0.498458294043;PBX1:0.475165924939;NFIX:0.472684371182;PRDM1:0.456517521373;PATZ1:0.452862521748;STAT1,3:0.45108629787;KLF4:0.450813542539;LHX3,4:0.447866395575;PITX1..3:0.430902097822;CDC5L:0.429746482877;FOXQ1:0.416958907747;GTF2I:0.388710716893;NANOG{mouse}:0.384970119093;TEAD1:0.382977118054;T:0.379972363452;PAX5:0.366881258706;HOX{A5,B5}:0.359663430167;MYBL2:0.342013615666;EVI1:0.341275102878;ONECUT1,2:0.338174684377;POU1F1:0.323476519291;GATA4:0.294603130971;TLX1..3_NFIC{dimer}:0.288451684838;ZFP161:0.288219853334;STAT5{A,B}:0.282762352356;GFI1B:0.274212868033;SPZ1:0.27051411934;HES1:0.250506562088;HIC1:0.245572163924;SP1:0.240246053833;AR:0.24003013512;TAL1_TCF{3,4,12}:0.238799409708;HOXA9_MEIS1:0.218811653935;EGR1..3:0.207643247877;BACH2:0.204207723058;EBF1:0.193693998299;ELK1,4_GABP{A,B1}:0.188398737144;POU2F1..3:0.187951377141;NKX2-3_NKX2-5:0.185168963761;MAZ:0.178286114592;NFATC1..3:0.177557330584;HAND1,2:0.147702237517;ESR1:0.13852905237;BREu{core}:0.124126603485;FOXP1:0.118216560581;TGIF1:0.109131452639;PAX3,7:0.093047757221;PAX1,9:0.0806177618024;NKX2-1,4:0.0708106432331;SOX{8,9,10}:0.0687871662136;XBP1:0.0652266615512;FOS_FOS{B,L1}_JUN{B,D}:0.0487965446664;TFAP2B:0.0399755841136;ALX1:0.0392571477971;LEF1_TCF7_TCF7L1,2:0.0383536469336;NFE2L2:0.0238017505965;HOX{A4,D4}:0.00904317530301;MED-1{core}:-0.00635047676443;GLI1..3:-0.0129053319401;ARID5B:-0.0175139857031;AHR_ARNT_ARNT2:-0.0246341969589;MTE{core}:-0.0343150873806;TFCP2:-0.0388114520502;ZBTB6:-0.0399332653266;FOSL2:-0.0446808294881;FOXO1,3,4:-0.0463512349008;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.0515639501902;CDX1,2,4:-0.0657409790052;HNF4A_NR2F1,2:-0.0744354596697;HBP1_HMGB_SSRP1_UBTF:-0.0770511407049;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.0835674141001;ZBTB16:-0.092693768617;ZNF423:-0.102373291133;RREB1:-0.115037652108;PPARG:-0.115480814009;NANOG:-0.118570424581;SOX5:-0.128641552888;HNF1A:-0.135871118979;TBX4,5:-0.137656041224;HLF:-0.145071020217;TP53:-0.148920931047;HSF1,2:-0.150495567618;SRF:-0.164130605494;PRRX1,2:-0.181715313192;RFX1:-0.191944352592;FOXM1:-0.192135110391;FOX{F1,F2,J1}:-0.198194760499;PAX6:-0.202333116193;RBPJ:-0.205315151969;CREB1:-0.210246295081;NFE2:-0.217381266054;CEBPA,B_DDIT3:-0.221497331343;MYFfamily:-0.225665797196;IKZF1:-0.23033348362;FOX{I1,J2}:-0.233980278854;ELF1,2,4:-0.239541446654;SOX2:-0.241544272033;POU5F1:-0.242196026373;RFX2..5_RFXANK_RFXAP:-0.262753929438;CUX2:-0.279151290554;ATF6:-0.303718471653;MTF1:-0.310945320008;GCM1,2:-0.312101432126;RUNX1..3:-0.338533671741;NR5A1,2:-0.342927348395;FOXA2:-0.35597178131;MEF2{A,B,C,D}:-0.359333899071;JUN:-0.38025012207;CRX:-0.384373948403;NR6A1:-0.388512084801;BPTF:-0.401907101427;NHLH1,2:-0.402306927959;ZNF148:-0.415993138762;ESRRA:-0.418413299441;GATA6:-0.451711349412;SPI1:-0.454715260926;NFKB1_REL_RELA:-0.455976694334;FOXN1:-0.460356831491;FOXP3:-0.464919514116;bHLH_family:-0.467469997646;HMGA1,2:-0.471044716553;DMAP1_NCOR{1,2}_SMARC:-0.473843951591;IRF7:-0.481256507876;TBP:-0.491013577399;SPIB:-0.497423801917;REST:-0.524439931518;HOX{A6,A7,B6,B7}:-0.525802877125;ZNF384:-0.534192057309;OCT4_SOX2{dimer}:-0.560032222845;RXRA_VDR{dimer}:-0.564616993872;IRF1,2:-0.572685666181;NFIL3:-0.578035162301;NFE2L1:-0.584262184237;ATF4:-0.584307312929;ATF5_CREB3:-0.589534368542;IKZF2:-0.591236481849;ADNP_IRX_SIX_ZHX:-0.596571589128;ETS1,2:-0.60258327953;SMAD1..7,9:-0.620914226317;SNAI1..3:-0.638285973988;HMX1:-0.673832017309;RORA:-0.765943825669;VSX1,2:-0.77049651252;MYOD1:-0.776196937529;NKX3-2:-0.785853404734;MAFB:-0.788009169757;POU6F1:-0.789966318911;STAT2,4,6:-0.8206483194;EP300:-0.86795885305;PAX2:-0.884372527909;FOXL1:-0.8855241496;ZEB1:-0.942101661359;ATF2:-0.949280287919;LMO2:-0.952669480575;HIF1A:-0.974516251619;FOX{D1,D2}:-0.990594345423;SREBF1,2:-1.00036881172;DBP:-1.03247887502;TLX2:-1.36610531701 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11319-117D5;search_select_hide=table117:FF:11319-117D5 | |||
}} | }} |
Latest revision as of 16:33, 3 June 2020
Name: | Fibroblast - Periodontal Ligament, donor2 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11962 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11962
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11962
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.263 |
10 | 10 | 0.988 |
100 | 100 | 0.839 |
101 | 101 | 0.542 |
102 | 102 | 0.936 |
103 | 103 | 0.0786 |
104 | 104 | 0.843 |
105 | 105 | 0.464 |
106 | 106 | 0.00116 |
107 | 107 | 0.286 |
108 | 108 | 0.481 |
109 | 109 | 0.373 |
11 | 11 | 0.454 |
110 | 110 | 0.577 |
111 | 111 | 0.683 |
112 | 112 | 0.0446 |
113 | 113 | 0.102 |
114 | 114 | 0.0407 |
115 | 115 | 0.707 |
116 | 116 | 0.791 |
117 | 117 | 0.814 |
118 | 118 | 0.643 |
119 | 119 | 0.2 |
12 | 12 | 0.968 |
120 | 120 | 0.3 |
121 | 121 | 0.832 |
122 | 122 | 0.0603 |
123 | 123 | 0.0525 |
124 | 124 | 0.425 |
125 | 125 | 0.771 |
126 | 126 | 0.695 |
127 | 127 | 0.519 |
128 | 128 | 0.106 |
129 | 129 | 0.208 |
13 | 13 | 0.486 |
130 | 130 | 0.0135 |
131 | 131 | 0.226 |
132 | 132 | 0.883 |
133 | 133 | 0.313 |
134 | 134 | 0.306 |
135 | 135 | 0.00135 |
136 | 136 | 0.464 |
137 | 137 | 0.199 |
138 | 138 | 0.116 |
139 | 139 | 5.99888e-5 |
14 | 14 | 0.163 |
140 | 140 | 0.943 |
141 | 141 | 0.535 |
142 | 142 | 0.963 |
143 | 143 | 0.0717 |
144 | 144 | 0.666 |
145 | 145 | 0.936 |
146 | 146 | 0.881 |
147 | 147 | 0.72 |
148 | 148 | 0.114 |
149 | 149 | 0.254 |
15 | 15 | 0.181 |
150 | 150 | 0.784 |
151 | 151 | 0.179 |
152 | 152 | 0.0471 |
153 | 153 | 0.877 |
154 | 154 | 0.979 |
155 | 155 | 0.188 |
156 | 156 | 0.589 |
157 | 157 | 0.101 |
158 | 158 | 0.0204 |
159 | 159 | 0.188 |
16 | 16 | 0.615 |
160 | 160 | 0.744 |
161 | 161 | 0.571 |
162 | 162 | 0.206 |
163 | 163 | 0.802 |
164 | 164 | 0.593 |
165 | 165 | 0.275 |
166 | 166 | 0.993 |
167 | 167 | 0.26 |
168 | 168 | 0.287 |
169 | 169 | 0.0421 |
17 | 17 | 0.22 |
18 | 18 | 0.567 |
19 | 19 | 0.992 |
2 | 2 | 0.66 |
20 | 20 | 0.578 |
21 | 21 | 0.298 |
22 | 22 | 0.597 |
23 | 23 | 0.0545 |
24 | 24 | 0.954 |
25 | 25 | 0.336 |
26 | 26 | 0.756 |
27 | 27 | 0.247 |
28 | 28 | 0.476 |
29 | 29 | 0.57 |
3 | 3 | 0.355 |
30 | 30 | 0.933 |
31 | 31 | 0.497 |
32 | 32 | 0.96 |
33 | 33 | 0.921 |
34 | 34 | 0.444 |
35 | 35 | 0.245 |
36 | 36 | 0.0882 |
37 | 37 | 0.132 |
38 | 38 | 0.402 |
39 | 39 | 0.794 |
4 | 4 | 0.457 |
40 | 40 | 0.172 |
41 | 41 | 0.0452 |
42 | 42 | 0.732 |
43 | 43 | 0.22 |
44 | 44 | 0.38 |
45 | 45 | 0.274 |
46 | 46 | 0.382 |
47 | 47 | 0.43 |
48 | 48 | 0.59 |
49 | 49 | 0.19 |
5 | 5 | 0.1 |
50 | 50 | 0.546 |
51 | 51 | 0.552 |
52 | 52 | 0.184 |
53 | 53 | 0.361 |
54 | 54 | 0.728 |
55 | 55 | 0.934 |
56 | 56 | 0.888 |
57 | 57 | 0.785 |
58 | 58 | 0.0491 |
59 | 59 | 0.471 |
6 | 6 | 0.932 |
60 | 60 | 0.00905 |
61 | 61 | 0.678 |
62 | 62 | 0.0486 |
63 | 63 | 0.735 |
64 | 64 | 0.514 |
65 | 65 | 0.13 |
66 | 66 | 0.0884 |
67 | 67 | 0.519 |
68 | 68 | 0.54 |
69 | 69 | 0.478 |
7 | 7 | 0.155 |
70 | 70 | 0.0308 |
71 | 71 | 0.233 |
72 | 72 | 0.249 |
73 | 73 | 0.11 |
74 | 74 | 0.957 |
75 | 75 | 0.244 |
76 | 76 | 0.766 |
77 | 77 | 0.329 |
78 | 78 | 0.631 |
79 | 79 | 0.842 |
8 | 8 | 0.512 |
80 | 80 | 0.00708 |
81 | 81 | 0.415 |
82 | 82 | 0.00592 |
83 | 83 | 0.381 |
84 | 84 | 0.937 |
85 | 85 | 0.00226 |
86 | 86 | 0.285 |
87 | 87 | 0.339 |
88 | 88 | 0.461 |
89 | 89 | 0.0601 |
9 | 9 | 0.461 |
90 | 90 | 0.279 |
91 | 91 | 0.866 |
92 | 92 | 0.105 |
93 | 93 | 0.752 |
94 | 94 | 0.311 |
95 | 95 | 0.347 |
96 | 96 | 0.284 |
97 | 97 | 0.966 |
98 | 98 | 0.102 |
99 | 99 | 0.0264 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11962
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000067 human fibroblast of periodontium sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0002320 (connective tissue cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
0000057 (fibroblast)
0002556 (fibroblast of periodontium)
UBERON: Anatomy
0000468 (multi-cellular organism)
0002384 (connective tissue)
0000033 (head)
0000479 (tissue)
0001007 (digestive system)
0004121 (ectoderm-derived structure)
0004119 (endoderm-derived structure)
0010314 (structure with developmental contribution from neural crest)
0011216 (organ system subdivision)
0000475 (organism subdivision)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000481 (multi-tissue structure)
0001444 (subdivision of head)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0000075 (subdivision of skeletal system)
0010317 (germ layer / neural crest derived structure)
0001555 (digestive tract)
0001758 (periodontium)
0000153 (anterior region of body)
0007811 (craniocervical region)
0002204 (musculoskeletal system)
0001434 (skeletal system)
0000165 (mouth)
0003672 (dentition)
0011137 (axial skeletal system)
0010323 (cranial skeletal system)
0003129 (skull)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000057 (fibroblast sample)
0000001 (sample)
0000067 (human fibroblast of periodontium sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)